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Aras Mattis, MD, PhD

Title(s)Assistant Professor, Pathology
SchoolSchool of Medicine
Address513 Parnassus Ave, HSW
San Francisco CA 94143
Phone415-514-3165
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    Regulation of Lipid Metabolism by miR-29a within Hepatocytes
    NIH/NIDDK K08DK098270Sep 1, 2013 - Jul 31, 2018
    Role: Principal Investigator

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    Collapse In The News

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Targeting acid ceramidase inhibits YAP/TAZ signaling to reduce fibrosis in mice. Sci Transl Med. 2020 Aug 19; 12(557). Alsamman S, Christenson SA, Yu A, Ayad NME, Mooring MS, Segal JM, Hu JK, Schaub JR, Ho SS, Rao V, Marlow MM, Turner SM, Sedki M, Pantano L, Ghoshal S, Ferreira DDS, Ma HY, Duwaerts CC, Espanol-Suner R, Wei L, Newcomb B, Mileva I, Canals D, Hannun YA, Chung RT, Mattis AN, Fuchs BC, Tager AM, Yimlamai D, Weaver VM, Mullen AC, Sheppard D, Chen JY. PMID: 32817366.
      View in: PubMed   Mentions:    Fields:    
    2. Ly6cLo non-classical monocytes promote resolution of rhesus rotavirus-mediated perinatal hepatic inflammation. Sci Rep. 2020 Apr 28; 10(1):7165. Alkhani A, Levy CS, Tsui M, Rosenberg KA, Polovina K, Mattis AN, Mack M, Van Dyken S, Wang BM, Maher JJ, Nijagal A. PMID: 32346042.
      View in: PubMed   Mentions:    Fields:    
    3. Utility of DNA flow cytometry in distinguishing between malignant and benign intrahepatic biliary lesions. Virchows Arch. 2020 Apr 15. Wen KW, Rabinovitch PS, Wang D, Mattis AN, Ferrell LD, Choi WT. PMID: 32296928.
      View in: PubMed   Mentions:    Fields:    
    4. DNA flow cytometric analysis of paraffin-embedded tissue for the diagnosis of malignancy in bile duct biopsies. Hum Pathol. 2020 May; 99:80-87. Lee H, Rabinovitch PS, Mattis AN, Kakar S, Choi WT. PMID: 32272125.
      View in: PubMed   Mentions:    Fields:    
    5. De novo somatic mutations and KRAS amplification are associated with cholangiocarcinoma in a patient with a history of choledochal cyst. J Pediatr Surg. 2020 Mar 24. Schwab ME, Song H, Mattis A, Phelps A, Vu LT, Huang FW, Nijagal A. PMID: 32295706.
      View in: PubMed   Mentions:    Fields:    
    6. Adipocyte JAK2 mediates spontaneous metabolic liver disease and hepatocellular carcinoma. JCI Insight. 2019 08 08; 5. Corbit KC, Wilson CG, Lowe D, Tran JL, Vera NB, Clasquin M, Mattis AN, Weiss EJ. PMID: 31393852.
      View in: PubMed   Mentions:    Fields:    
    7. Diagnosis, risk stratification, and management of ampullary dysplasia by DNA flow cytometric analysis of paraffin-embedded tissue. Mod Pathol. 2019 09; 32(9):1291-1302. Wen KW, Kim GE, Rabinovitch PS, Wang D, Mattis AN, Choi WT. PMID: 30976103.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Evaluation of commonly used ectoderm markers in iPSC trilineage differentiation. Stem Cell Res. 2019 05; 37:101434. Kuang YL, Munoz A, Nalula G, Santostefano KE, Sanghez V, Sanchez G, Terada N, Mattis AN, Iacovino M, Iribarren C, Krauss RM, Medina MW. PMID: 30999275.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    9. Utility of DNA Flow Cytometric Analysis of Paraffin-embedded Tissue in the Risk Stratification and Management of 'Indefinite for dysplasia' in Patients With Inflammatory Bowel Disease. J Crohns Colitis. 2019 Mar 30; 13(4):472-481. Wen KW, Rabinovitch PS, Wang D, Huang D, Mattis AN, Choi WT. PMID: 30423034.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    10. Depletion of murine fetal hematopoietic stem cells with c-Kit receptor and CD47 blockade improves neonatal engraftment. Blood Adv. 2018 12 26; 2(24):3602-3607. Witt RG, Wang B, Nguyen QH, Eikani C, Mattis AN, MacKenzie TC. PMID: 30567724.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    11. DNA content analysis of colorectal serrated lesions detects an aneuploid subset of inflammatory bowel disease-associated serrated epithelial change and traditional serrated adenomas. Histopathology. 2018 Sep; 73(3):464-472. Choi WT, Wen KW, Rabinovitch PS, Huang D, Mattis AN, Gill RM. PMID: 29772067.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Use of DNA flow cytometry in the diagnosis, risk stratification, and management of gastric epithelial dysplasia. Mod Pathol. 2018 10; 31(10):1578-1587. Wen KW, Rabinovitch PS, Huang D, Mattis AN, Lauwers GY, Choi WT. PMID: 29789650.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. De novo formation of the biliary system by TGFß-mediated hepatocyte transdifferentiation. Nature. 2018 05; 557(7704):247-251. Schaub JR, Huppert KA, Kurial SNT, Hsu BY, Cast AE, Donnelly B, Karns RA, Chen F, Rezvani M, Luu HY, Mattis AN, Rougemont AL, Rosenthal P, Huppert SS, Willenbring H. PMID: 29720662.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    14. CD18 deficiency improves liver injury in the MCD model of steatohepatitis. PLoS One. 2017; 12(9):e0183912. Pierce AA, Duwaerts CC, Siao K, Mattis AN, Goodsell A, Baron JL, Maher JJ. PMID: 28873429.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    15. Association of Aneuploidy and Flat Dysplasia With Development of High-Grade Dysplasia or Colorectal Cancer in Patients With Inflammatory Bowel Disease. Gastroenterology. 2017 12; 153(6):1492-1495.e4. Tsai JH, Rabinovitch PS, Huang D, Small T, Mattis AN, Kakar S, Choi WT. PMID: 28843957.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    16. Diagnosis and risk stratification of Barrett's dysplasia by flow cytometric DNA analysis of paraffin-embedded tissue. Gut. 2018 07; 67(7):1229-1238. Choi WT, Tsai JH, Rabinovitch PS, Small T, Huang D, Mattis AN, Kakar S. PMID: 28642331.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    17. Diffusion-weighted imaging of hyperpolarized [13 C]urea in mouse liver. J Magn Reson Imaging. 2018 01; 47(1):141-151. Marco-Rius I, Gordon JW, Mattis AN, Bok R, Delos Santos R, Sukumar S, Larson PEZ, Vigneron DB, Ohliger MA. PMID: 28419644.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    18. A Novel Tumor-Activated Prodrug Strategy Targeting Ferrous Iron Is Effective in Multiple Preclinical Cancer Models. J Med Chem. 2016 12 22; 59(24):11161-11170. Spangler B, Fontaine SD, Shi Y, Sambucetti L, Mattis AN, Hann B, Wells JA, Renslo AR. PMID: 27936709.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    19. Heightened Immune Activation in Fetuses with Gastroschisis May Be Blocked by Targeting IL-5. J Immunol. 2016 06 15; 196(12):4957-66. Frascoli M, Jeanty C, Fleck S, Moradi PW, Keating S, Mattis AN, Tang Q, MacKenzie TC. PMID: 27183609.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    20. Human stem cells from single blastomeres reveal pathways of embryonic or trophoblast fate specification. Development. 2015 Dec 01; 142(23):4010-25. Zdravkovic T, Nazor KL, Larocque N, Gormley M, Donne M, Hunkapillar N, Giritharan G, Bernstein HS, Wei G, Hebrok M, Zeng X, Genbacev O, Mattis A, McMaster MT, Krtolica A, Valbuena D, Simón C, Laurent LC, Loring JF, Fisher SJ. PMID: 26483210.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    21. A screen in mice uncovers repression of lipoprotein lipase by microRNA-29a as a mechanism for lipid distribution away from the liver. Hepatology. 2015 Jan; 61(1):141-52. Mattis AN, Song G, Hitchner K, Kim RY, Lee AY, Sharma AD, Malato Y, McManus MT, Esau CC, Koller E, Koliwad S, Lim LP, Maher JJ, Raffai RL, Willenbring H. PMID: 25131933.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    22. Mouse liver repopulation with hepatocytes generated from human fibroblasts. Nature. 2014 Apr 03; 508(7494):93-7. Zhu S, Rezvani M, Harbell J, Mattis AN, Wolfe AR, Benet LZ, Willenbring H, Ding S. PMID: 24572354.
      View in: PubMed   Mentions: 89     Fields:    Translation:HumansAnimalsCells
    23. A ZFN/piggyBac step closer to autologous liver cell therapy. Hepatology. 2012 Jun; 55(6):2033-5. Mattis AN, Willenbring H. PMID: 22422378.
      View in: PubMed   Mentions: 1     Fields:    
    24. Expression of glypican-3 in undifferentiated embryonal sarcoma and mesenchymal hamartoma of the liver. Hum Pathol. 2012 May; 43(5):695-701. Levy M, Trivedi A, Zhang J, Miles L, Mattis AN, Kim GE, Lassman C, Anders RA, Misdraji J, Yerian LM, Xu H, Dhall D, Wang HL. PMID: 21937079.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    25. Clinical diagnosis of segmental arterial mediolysis: differentiation from vasculitis and other mimics. Arthritis Care Res (Hoboken). 2010 Nov; 62(11):1655-60. Baker-LePain JC, Stone DH, Mattis AN, Nakamura MC, Fye KH. PMID: 20662047.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    26. Purification and characterization of bacteriophage P22 Xis protein. J Bacteriol. 2008 Sep; 190(17):5781-96. Mattis AN, Gumport RI, Gardner JF. PMID: 18502866.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    27. IntDOT interactions with core- and arm-type sites of the conjugative transposon CTnDOT. J Bacteriol. 2007 Apr; 189(7):2692-701. Dichiara JM, Mattis AN, Gardner JF. PMID: 17277054.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    28. Integration host factor: putting a twist on protein-DNA recognition. J Mol Biol. 2003 Jul 11; 330(3):493-502. Lynch TW, Read EK, Mattis AN, Gardner JF, Rice PA. PMID: 12842466.
      View in: PubMed   Mentions: 30     Fields:    Translation:Cells
    29. 20q13.2 amplification in intraductal hyperplasia adjacent to in situ and invasive ductal carcinoma of the breast. Virchows Arch. 1999 Nov; 435(5):469-72. Werner M, Mattis A, Aubele M, Cummings M, Zitzelsberger H, Hutzler P, Höfler H. PMID: 10592049.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
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