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Aras Mattis, MD, PhD

TitleAssistant Professor
InstitutionUniversity of California San Francisco
DepartmentPathology
Address513 Parnassus Ave
San Francisco CA 94143
Phone415-514-3062
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    Collapse Research 
    Collapse Research Activities and Funding
    Regulation of Lipid Metabolism by miR-29a within Hepatocytes
    NIH/NIDDK K08DK098270Sep 1, 2013 - Jul 31, 2018
    Role: Principal Investigator

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    Collapse In The News

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Wen KW, Rabinovitch PS, Wang D, Huang D, Mattis AN, Choi WT. Utility of DNA Flow Cytometric Analysis of Paraffin-Embedded Tissue in the Risk Stratification and Management of "Indefinite for Dysplasia" in Patients with Inflammatory Bowel Disease. J Crohns Colitis. 2018 Nov 13. PMID: 30423034.
      View in: PubMed
    2. Wen KW, Rabinovitch PS, Huang D, Mattis AN, Lauwers GY, Choi WT. Use of DNA flow cytometry in the diagnosis, risk stratification, and management of gastric epithelial dysplasia. Mod Pathol. 2018 May 22. PMID: 29789650.
      View in: PubMed
    3. Choi WT, Wen KW, Rabinovitch PS, Huang D, Mattis AN, Gill RM. DNA Content Analysis of Colorectal Serrated Lesions Detects an Aneuploid Subset of Inflammatory Bowel Disease-Associated Serrated Epithelial Change and Traditional Serrated Adenomas. Histopathology. 2018 May 17. PMID: 29772067.
      View in: PubMed
    4. Schaub JR, Huppert KA, Kurial SNT, Hsu BY, Cast AE, Donnelly B, Karns RA, Chen F, Rezvani M, Luu HY, Mattis AN, Rougemont AL, Rosenthal P, Huppert SS, Willenbring H. De novo formation of the biliary system by TGFß-mediated hepatocyte transdifferentiation. Nature. 2018 May 02. PMID: 29720662.
      View in: PubMed
    5. Pierce AA, Duwaerts CC, Siao K, Mattis AN, Goodsell A, Baron JL, Maher JJ. CD18 deficiency improves liver injury in the MCD model of steatohepatitis. PLoS One. 2017; 12(9):e0183912. PMID: 28873429.
      View in: PubMed
    6. Tsai JH, Rabinovitch PS, Huang D, Small T, Mattis AN, Kakar S, Choi WT. Association of Aneuploidy and Flat Dysplasia With Development of High-Grade Dysplasia or Colorectal Cancer in Patients With Inflammatory Bowel Disease. Gastroenterology. 2017 12; 153(6):1492-1495.e4. PMID: 28843957.
      View in: PubMed
    7. Choi WT, Tsai JH, Rabinovitch PS, Small T, Huang D, Mattis AN, Kakar S. Diagnosis and risk stratification of Barrett's dysplasia by flow cytometric DNA analysis of paraffin-embedded tissue. Gut. 2017 Jun 22. PMID: 28642331.
      View in: PubMed
    8. Marco-Rius I, Gordon JW, Mattis AN, Bok R, Delos Santos R, Sukumar S, Larson PEZ, Vigneron DB, Ohliger MA. Diffusion-weighted imaging of hyperpolarized [13 C]urea in mouse liver. J Magn Reson Imaging. 2018 Jan; 47(1):141-151. PMID: 28419644.
      View in: PubMed
    9. Spangler B, Fontaine SD, Shi Y, Sambucetti L, Mattis AN, Hann B, Wells JA, Renslo AR. A Novel Tumor-Activated Prodrug Strategy Targeting Ferrous Iron Is Effective in Multiple Preclinical Cancer Models. J Med Chem. 2016 Dec 22; 59(24):11161-11170. PMID: 27936709.
      View in: PubMed
    10. Frascoli M, Jeanty C, Fleck S, Moradi PW, Keating S, Mattis AN, Tang Q, MacKenzie TC. Heightened Immune Activation in Fetuses with Gastroschisis May Be Blocked by Targeting IL-5. J Immunol. 2016 06 15; 196(12):4957-66. PMID: 27183609; PMCID: PMC4977025 [Available on 06/15/17].
    11. Zdravkovic T, Nazor KL, Larocque N, Gormley M, Donne M, Hunkapillar N, Giritharan G, Bernstein HS, Wei G, Hebrok M, Zeng X, Genbacev O, Mattis A, McMaster MT, Krtolica A, Valbuena D, Simón C, Laurent LC, Loring JF, Fisher SJ. Human stem cells from single blastomeres reveal pathways of embryonic or trophoblast fate specification. Development. 2015 Dec 01; 142(23):4010-25. PMID: 26483210; PMCID: PMC4712832.
    12. Mattis AN, Song G, Hitchner K, Kim RY, Lee AY, Sharma AD, Malato Y, McManus MT, Esau CC, Koller E, Koliwad S, Lim LP, Maher JJ, Raffai RL, Willenbring H. A screen in mice uncovers repression of lipoprotein lipase by microRNA-29a as a mechanism for lipid distribution away from the liver. Hepatology. 2015 Jan; 61(1):141-52. PMID: 25131933; PMCID: PMC4465779.
    13. Zhu S, Rezvani M, Harbell J, Mattis AN, Wolfe AR, Benet LZ, Willenbring H, Ding S. Mouse liver repopulation with hepatocytes generated from human fibroblasts. Nature. 2014 Apr 03; 508(7494):93-7. PMID: 24572354; PMCID: PMC4161230.
    14. Mattis AN, Willenbring H. A ZFN/piggyBac step closer to autologous liver cell therapy. Hepatology. 2012 Jun; 55(6):2033-5. PMID: 22422378.
      View in: PubMed
    15. Levy M, Trivedi A, Zhang J, Miles L, Mattis AN, Kim GE, Lassman C, Anders RA, Misdraji J, Yerian LM, Xu H, Dhall D, Wang HL. Expression of glypican-3 in undifferentiated embryonal sarcoma and mesenchymal hamartoma of the liver. Hum Pathol. 2012 May; 43(5):695-701. PMID: 21937079; PMCID: PMC3568522.
    16. Baker-LePain JC, Stone DH, Mattis AN, Nakamura MC, Fye KH. Clinical diagnosis of segmental arterial mediolysis: differentiation from vasculitis and other mimics. Arthritis Care Res (Hoboken). 2010 Nov; 62(11):1655-60. PMID: 20662047; PMCID: PMC2974779.
    17. Mattis AN, Gumport RI, Gardner JF. Purification and characterization of bacteriophage P22 Xis protein. J Bacteriol. 2008 Sep; 190(17):5781-96. PMID: 18502866; PMCID: PMC2519534.
    18. Dichiara JM, Mattis AN, Gardner JF. IntDOT interactions with core- and arm-type sites of the conjugative transposon CTnDOT. J Bacteriol. 2007 Apr; 189(7):2692-701. PMID: 17277054; PMCID: PMC1855790.
    19. Lynch TW, Read EK, Mattis AN, Gardner JF, Rice PA. Integration host factor: putting a twist on protein-DNA recognition. J Mol Biol. 2003 Jul 11; 330(3):493-502. PMID: 12842466.
      View in: PubMed