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Morris Schambelan, MD

TitleProfessor
InstitutionUniversity of California San Francisco
DepartmentMedicine
Address1001 Potrero Ave
San Francisco CA 94110
Phone415-206-3351
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoResidency School of Medicine

    Collapse Research 
    Collapse Research Activities and Funding
    Uridine Supplementation, Mitochondrial Function, and Glucose Metabolism in HIV
    NIH/NCCIH R21AT003374Aug 1, 2006 - Jun 30, 2010
    Role: Principal Investigator
    Can IGF-I/IGFBP-3 Reverse Central Fat Accumulation?
    NIH/NIDDK R21DK069185Jul 2, 2004 - Jun 30, 2008
    Role: Principal Investigator
    Leptin Treatment of HIV-Associated Lipodystrophy
    NIH/NIDDK R01DK063640Sep 30, 2002 - Jul 31, 2008
    Role: Principal Investigator
    Ergogenic Effects of Creatine Supp .in HIV-Assoc.Wasting
    NIH/NCCIH R01AT000491Jul 1, 2000 - Apr 30, 2004
    Role: Principal Investigator
    MITIGATION OF EPISODIC WASTING IN HIV INFECTION
    NIH/NIDDK R01DK052610Sep 6, 1997 - Aug 31, 2003
    Role: Principal Investigator
    ANABOLIC THERAPIES AND THEIR METABOLIC EFFECTS IN AIDS
    NIH/NIDDK R01DK045833Sep 30, 1992 - May 31, 2004
    Role: Principal Investigator
    RENIN, ANGIOTENSIN, STEROIDS, IONS AND BLOOD PRESSURE
    NIH/NHLBI R01HL011046Jan 1, 1977 - Mar 31, 1996
    Role: Principal Investigator
    A Resource for Biomedical Mass Spectrometry
    NIH P41RR000954Jun 1, 1975 - Dec 31, 2014
    Role: Co-Investigator
    General Clinical Research Center
    NIH/NCRR M01RR000083Oct 1, 1974 - Nov 30, 2007
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Lee AP, Mulligan K, Schambelan M, Murphy EJ, Weiss EJ. Growth hormone receptor antagonism with pegvisomant in insulin resistant non-diabetic men: A phase II pilot study. F1000Res. 2017; 6:614. PMID: 28713554.
      View in: PubMed
    2. Schwarz JM, Noworolski SM, Wen MJ, Dyachenko A, Prior JL, Weinberg ME, Herraiz LA, Tai VW, Bergeron N, Bersot TP, Rao MN, Schambelan M, Mulligan K. Effect of a High-Fructose Weight-Maintaining Diet on Lipogenesis and Liver Fat. J Clin Endocrinol Metab. 2015 Jun; 100(6):2434-42. PMID: 25825943; PMCID: PMC4454806.
    3. Rao MN, Neylan TC, Grunfeld C, Mulligan K, Schambelan M, Schwarz JM. Subchronic sleep restriction causes tissue-specific insulin resistance. J Clin Endocrinol Metab. 2015 Apr; 100(4):1664-71. PMID: 25658017; PMCID: PMC4399283.
    4. Khanijow K, Unemori P, Leslie KS, Mulligan K, Schambelan M, Maurer T. Cutis Verticis Gyrata in Men Affected by HIV-Related Lipodystrophy. Dermatol Res Pract. 2013; 2013:941740. PMID: 24159328; PMCID: PMC3789479.
    5. Campos GM, Rabl C, Havel PJ, Rao M, Schwarz JM, Schambelan M, Mulligan K. Changes in post-prandial glucose and pancreatic hormones, and steady-state insulin and free fatty acids after gastric bypass surgery. Surg Obes Relat Dis. 2014 Jan-Feb; 10(1):1-8. PMID: 24209879; PMCID: PMC3896512.
    6. Park-Sigal J, Don BR, Porzig A, Recker R, Griswold V, Sebastian A, Duh QY, Portale AA, Shoback D, Schambelan M. Severe hypercalcemic hyperparathyroidism developing in a patient with hyperaldosteronism and renal resistance to parathyroid hormone. J Bone Miner Res. 2013 Mar; 28(3):700-8. PMID: 23074096.
      View in: PubMed
    7. Rao MN, Schambelan M, Tai VW, Abrams DI, Khatami H, Havel PJ, Sakkas G, Mulligan K. Assessing the Association between Leptin and Bone Mineral Density in HIV-Infected Men. AIDS Res Treat. 2012; 2012:103072. PMID: 22966425; PMCID: PMC3433112.
    8. Morley JE, Abbatecola AM, Argiles JM, Baracos V, Bauer J, Bhasin S, Cederholm T, Coats AJ, Cummings SR, Evans WJ, Fearon K, Ferrucci L, Fielding RA, Guralnik JM, Harris TB, Inui A, Kalantar-Zadeh K, Kirwan BA, Mantovani G, Muscaritoli M, Newman AB, Rossi-Fanelli F, Rosano GM, Roubenoff R, Schambelan M, Sokol GH, Storer TW, Vellas B, von Haehling S, Yeh SS, Anker SD. Sarcopenia with limited mobility: an international consensus. J Am Med Dir Assoc. 2011 Jul; 12(6):403-9. PMID: 21640657.
      View in: PubMed
    9. Winterstein AG, Heckbert SR, Schambelan M. Intensive glucose lowering and cardiovascular outcomes. N Engl J Med. 2011 Jun 09; 364(23):2263; author reply 2264. PMID: 21651404.
      View in: PubMed
    10. Masharani UB, Maddux BA, Li X, Sakkas GK, Mulligan K, Schambelan M, Goldfine ID, Youngren JF. Insulin resistance in non-obese subjects is associated with activation of the JNK pathway and impaired insulin signaling in skeletal muscle. PLoS One. 2011 May 11; 6(5):e19878. PMID: 21589939; PMCID: PMC3092773.
    11. Weinberg ME, Roman MC, Jacob P, Wen M, Cheung P, Walker UA, Mulligan K, Schambelan M. Enhanced uridine bioavailability following administration of a triacetyluridine-rich nutritional supplement. PLoS One. 2011 Feb 17; 6(2):e14709. PMID: 21379380; PMCID: PMC3040752.
    12. Taylor SA, Lee GA, Pao VY, Anthonypillai J, Aweeka FT, Schwarz JM, Mulligan K, Schambelan M, Grunfeld C. Boosting dose ritonavir does not alter peripheral insulin sensitivity in healthy HIV-seronegative volunteers. J Acquir Immune Defic Syndr. 2010 Nov; 55(3):361-4. PMID: 20595906; PMCID: PMC3164483.
    13. Rao MN, Mulligan K, Tai V, Wen MJ, Dyachenko A, Weinberg M, Li X, Lang T, Grunfeld C, Schwarz JM, Schambelan M. Effects of insulin-like growth factor (IGF)-I/IGF-binding protein-3 treatment on glucose metabolism and fat distribution in human immunodeficiency virus-infected patients with abdominal obesity and insulin resistance. J Clin Endocrinol Metab. 2010 Sep; 95(9):4361-6. PMID: 20610601; PMCID: PMC2936071.
    14. Shrestha S, Irvin MR, Taylor KD, Wiener HW, Pajewski NM, Haritunians T, Delaney JA, Schambelan M, Polak JF, Arnett DK, Chen YD, Grunfeld C. A genome-wide association study of carotid atherosclerosis in HIV-infected men. AIDS. 2010 Feb 20; 24(4):583-92. PMID: 20009918; PMCID: PMC3072760.
    15. Pao VY, Lee GA, Taylor S, Aweeka FT, Schwarz JM, Mulligan K, Schambelan M, Grunfeld C. The protease inhibitor combination lopinavir/ritonavir does not decrease insulin secretion in healthy, HIV-seronegative volunteers. AIDS. 2010 Jan 16; 24(2):265-70. PMID: 19890203.
      View in: PubMed
    16. Sakkas GK, Schambelan M, Mulligan K. Can the use of creatine supplementation attenuate muscle loss in cachexia and wasting? Curr Opin Clin Nutr Metab Care. 2009 Nov; 12(6):623-7. PMID: 19741514; PMCID: PMC2905310.
    17. Campos GM, Rabl C, Peeva S, Ciovica R, Rao M, Schwarz JM, Havel P, Schambelan M, Mulligan K. Improvement in peripheral glucose uptake after gastric bypass surgery is observed only after substantial weight loss has occurred and correlates with the magnitude of weight lost. J Gastrointest Surg. 2010 Jan; 14(1):15-23. PMID: 19838759.
      View in: PubMed
    18. Lee GA, Schwarz JM, Patzek S, Kim S, Dyachenko A, Wen M, Mulligan K, Schambelan M, Grunfeld C. The acute effects of HIV protease inhibitors on insulin suppression of glucose production in healthy HIV-negative men. J Acquir Immune Defic Syndr. 2009 Oct 01; 52(2):246-8. PMID: 19680131; PMCID: PMC3164488.
    19. Sakkas GK, Mulligan K, Dasilva M, Doyle JW, Khatami H, Schleich T, Kent-Braun JA, Schambelan M. Creatine fails to augment the benefits from resistance training in patients with HIV infection: a randomized, double-blind, placebo-controlled study. PLoS One. 2009; 4(2):e4605. PMID: 19242554; PMCID: PMC2646129.
    20. Mulligan K, Khatami H, Schwarz JM, Sakkas GK, DePaoli AM, Tai VW, Wen MJ, Lee GA, Grunfeld C, Schambelan M. The effects of recombinant human leptin on visceral fat, dyslipidemia, and insulin resistance in patients with human immunodeficiency virus-associated lipoatrophy and hypoleptinemia. J Clin Endocrinol Metab. 2009 Apr; 94(4):1137-44. PMID: 19174500; PMCID: PMC2682465.
    21. Schambelan M, Wilson PW, Yarasheski KE, Cade WT, Dávila-Román VG, D'Agostino RB, Helmy TA, Law M, Mondy KE, Nachman S, Peterson LR, Worm SW. Development of appropriate coronary heart disease risk prediction models in HIV-infected patients. Circulation. 2008 Jul 08; 118(2):e48-53. PMID: 18566316; PMCID: PMC2648861.
    22. Grinspoon SK, Grunfeld C, Kotler DP, Currier JS, Lundgren JD, Dubé MP, Lipshultz SE, Hsue PY, Squires K, Schambelan M, Wilson PW, Yarasheski KE, Hadigan CM, Stein JH, Eckel RH. State of the science conference: Initiative to decrease cardiovascular risk and increase quality of care for patients living with HIV/AIDS: executive summary. Circulation. 2008 Jul 08; 118(2):198-210. PMID: 18566320; PMCID: PMC3642216.
    23. Lee GA, Rao M, Mulligan K, Lo JC, Aweeka F, Schwarz JM, Schambelan M, Grunfeld C. Effects of ritonavir and amprenavir on insulin sensitivity in healthy volunteers. AIDS. 2007 Oct 18; 21(16):2183-90. PMID: 18090045; PMCID: PMC3167072.
    24. Li X, Youngren JF, Hyun B, Sakkas GK, Mulligan K, Majumdar S, Masharani UB, Schambelan M, Goldfine ID. Technical evaluation of in vivo abdominal fat and IMCL quantification using MRI and MRSI at 3 T. Magn Reson Imaging. 2008 Feb; 26(2):188-97. PMID: 17683890; PMCID: PMC2713003.
    25. Mulligan K, Zackin R, Von Roenn JH, Chesney MA, Egorin MJ, Sattler FR, Benson CA, Liu T, Umbleja T, Shriver S, Auchus RJ, Schambelan M. Testosterone supplementation of megestrol therapy does not enhance lean tissue accrual in men with human immunodeficiency virus-associated weight loss: a randomized, double-blind, placebo-controlled, multicenter trial. J Clin Endocrinol Metab. 2007 Feb; 92(2):563-70. PMID: 17090640.
      View in: PubMed
    26. Lee GA, Lo JC, Aweeka F, Schwarz JM, Mulligan K, Schambelan M, Grunfeld C. Single-dose lopinavir-ritonavir acutely inhibits insulin-mediated glucose disposal in healthy volunteers. Clin Infect Dis. 2006 Sep 01; 43(5):658-60. PMID: 16886163; PMCID: PMC3205942.
    27. Lo JC, Kazemi MR, Hsue PY, Martin JN, Deeks SG, Schambelan M, Mulligan K. The relationship between nucleoside analogue treatment duration, insulin resistance, and fasting arterialized lactate level in patients with HIV infection. Clin Infect Dis. 2005 Nov 01; 41(9):1335-40. PMID: 16206112.
      View in: PubMed
    28. Schwarz JM, Lee GA, Park S, Noor MA, Lee J, Wen M, Lo JC, Mulligan K, Schambelan M, Grunfeld C. Indinavir increases glucose production in healthy HIV-negative men. AIDS. 2004 Sep 03; 18(13):1852-4. PMID: 15316349.
      View in: PubMed
    29. Lo JC, Mulligan K, Noor MA, Lee GA, Schwarz JM, Grunfeld C, Schambelan M. The effects of low-dose growth hormone in HIV-infected men with fat accumulation: a pilot study. Clin Infect Dis. 2004 Sep 01; 39(5):732-5. PMID: 15356790; PMCID: PMC3170406.
    30. Lee GA, Mafong DD, Noor MA, Lo JC, Mulligan K, Schwarz JM, Schambelan M, Grunfeld C. HIV protease inhibitors increase adiponectin levels in HIV-negative men. J Acquir Immune Defic Syndr. 2004 May 01; 36(1):645-7. PMID: 15097312.
      View in: PubMed
    31. Lee GA, Seneviratne T, Noor MA, Lo JC, Schwarz JM, Aweeka FT, Mulligan K, Schambelan M, Grunfeld C. The metabolic effects of lopinavir/ritonavir in HIV-negative men. AIDS. 2004 Mar 05; 18(4):641-9. PMID: 15090769; PMCID: PMC3166345.
    32. Zambon AC, McDearmon EL, Salomonis N, Vranizan KM, Johansen KL, Adey D, Takahashi JS, Schambelan M, Conklin BR. Time- and exercise-dependent gene regulation in human skeletal muscle. Genome Biol. 2003; 4(10):R61. PMID: 14519196; PMCID: PMC328450.
    33. Abrams DI, Hilton JF, Leiser RJ, Shade SB, Elbeik TA, Aweeka FT, Benowitz NL, Bredt BM, Kosel B, Aberg JA, Deeks SG, Mitchell TF, Mulligan K, Bacchetti P, McCune JM, Schambelan M. Short-term effects of cannabinoids in patients with HIV-1 infection: a randomized, placebo-controlled clinical trial. Ann Intern Med. 2003 Aug 19; 139(4):258-66. PMID: 12965981.
      View in: PubMed
    34. Schambelan M, Benson CA, Carr A, Currier JS, Dubé MP, Gerber JG, Grinspoon SK, Grunfeld C, Kotler DP, Mulligan K, Powderly WG, Saag MS. Management of metabolic complications associated with antiretroviral therapy for HIV-1 infection: recommendations of an International AIDS Society-USA panel. J Acquir Immune Defic Syndr. 2002 Nov 01; 31(3):257-75. PMID: 12439201.
      View in: PubMed
    35. Tai VW, Schambelan M, Algren H, Shayevich C, Mulligan K. Effects of recombinant human growth hormone on fat distribution in patients with human immunodeficiency virus-associated wasting. Clin Infect Dis. 2002 Nov 15; 35(10):1258-62. PMID: 12410487.
      View in: PubMed
    36. Mulligan K, Schambelan M. Anabolic treatment with GH, IGF-I, or anabolic steroids in patients with HIV-associated wasting. Int J Cardiol. 2002 Sep; 85(1):151-9. PMID: 12163220.
      View in: PubMed
    37. Napolitano LA, Lo JC, Gotway MB, Mulligan K, Barbour JD, Schmidt D, Grant RM, Halvorsen RA, Schambelan M, McCune JM. Increased thymic mass and circulating naive CD4 T cells in HIV-1-infected adults treated with growth hormone. AIDS. 2002 May 24; 16(8):1103-11. PMID: 12004268.
      View in: PubMed
    38. Noor MA, Seneviratne T, Aweeka FT, Lo JC, Schwarz JM, Mulligan K, Schambelan M, Grunfeld C. Indinavir acutely inhibits insulin-stimulated glucose disposal in humans: a randomized, placebo-controlled study. AIDS. 2002 Mar 29; 16(5):F1-8. PMID: 11964551; PMCID: PMC3166537.
    39. Schwarz JM, Mulligan K, Lee J, Lo JC, Wen M, Noor MA, Grunfeld C, Schambelan M. Effects of recombinant human growth hormone on hepatic lipid and carbohydrate metabolism in HIV-infected patients with fat accumulation. J Clin Endocrinol Metab. 2002 Feb; 87(2):942. PMID: 11836345.
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    40. Shimkets RA, Warnock DG, Bositis CM, Nelson-Williams C, Hansson JH, Schambelan M, Gill JR, Ulick S, Milora RV, Findling JW. Liddle's syndrome: heritable human hypertension caused by mutations in the beta subunit of the epithelial sodium channel. Cell. 1994 Nov 04; 79(3):407-14. PMID: 7954808.
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    41. Lim RC, Nakayama DK, Biglieri EG, Schambelan M, Hunt TK. Primary aldosteronism: changing concepts in diagnosis and management. Am J Surg. 1986 Jul; 152(1):116-21. PMID: 3728804.
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    42. Biglieri EG, Schambelan M. Endocrine hypertension. Clin Endocrinol Metab. 1981 Nov; 10(3):ix-xi. PMID: 7344806.
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    43. Korobkin M, Glickman MG, Schambelan M. Segmental renal vein sampling for renin. Radiology. 1976 Feb; 118(2):307-13. PMID: 1250963.
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    44. Clark OH, Hall AD, Schambelan M. Clinical manifestations of adrenal hemorrhage. Am J Surg. 1974 Aug; 128(2):219-24. PMID: 4846502.
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    45. Golde DW, Schambelan M, Weintraub BD, Rosen SW. Gonadotropin-secreting renal carcinoma. Cancer. 1974 Apr; 33(4):1048-53. PMID: 4819211.
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    46. Eichner HL, Schambelan M, Biglieri EG. Systemic lupus erythematosus with adrenal insufficiency. Am J Med. 1973 Nov; 55(5):700-5. PMID: 4356101.
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    47. Schambelan M, Slaton PE, Murray JF, Biglieri EG. Adrenal insufficiency and inappropriate secretion of antidiuretic hormone. Occurrence in a patient with carcinoma of the lung. Arch Intern Med. 1969 Aug; 124(2):197-201. PMID: 5797078.
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    48. Schambelan M, Sussman S. Encephalitis and purpura with influenza infection. A case report. Am J Dis Child. 1966 Mar; 111(3):302-3. PMID: 5904471.
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