Slyvia Singer, MD

Title(s)Professor, Pediatrics
SchoolSchool of Medicine
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    Collapse Research 
    Collapse Research Activities and Funding
    Development of a Clinical Hemoglobin Modulator
    NIH R33HL147845Jun 1, 2020 - May 31, 2023
    Role: Co-Principal Investigator
    Pulmonary Hypertension in Thalassemia
    NIH K23HL077409Aug 1, 2005 - Jul 31, 2010
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Fertility and Pregnancy in Women with Transfusion-Dependent Thalassemia. Hematol Oncol Clin North Am. 2023 04; 37(2):393-411. Sayani FA, Singer ST, Carlberg KT, Vichinsky EP. PMID: 36907611.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Anterior Pituitary Volume in Patients with Transfusion Dependent Anemias: Volumetric Approaches and Relation to Pituitary MRI‑R2. Clin Neuroradiol. 2022 Mar; 32(1):259-267. Berliner C, Wang ZJ, Singer ST, Grosse R, McDonough RV, Padua E, Yuan Q, Weyhmiller M, James E, Vichinsky E, Adam G, Yamamura J, Bannas P, Fischer R, Schoennagel BP. PMID: 34709410; PMCID: PMC8894216.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    3. Primary HBB gene mutation severity and long-term outcomes in a global cohort of β-thalassaemia. Br J Haematol. 2022 01; 196(2):414-423. Musallam KM, Vitrano A, Meloni A, Addario Pollina S, Di Marco V, Hussain Ansari S, Filosa A, Ricchi P, Ceci A, Daar S, Vlachaki E, Singer ST, Naserullah ZA, Pepe A, Scondotto S, Dardanoni G, Karimi M, El-Beshlawy A, Hajipour M, Bonifazi F, Vichinsky E, Taher AT, Sankaran VG, Maggio A, International Working Group on Thalassemia (IWG-THAL). PMID: 34697800.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansPHPublic Health
    4. Pituitary iron and factors predictive of fertility status in transfusion dependent thalassemia. Haematologica. 2021 06 01; 106(6):1740-1744. Singer ST, Fischer R, Allen I, Lal A, Vichinsky E, Yuan Q, Wang ZJ. PMID: 33121232; PMCID: PMC8168491.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    5. Fertility and Pregnancy in Women with Transfusion-Dependent Thalassemia. Hematol Oncol Clin North Am. 2018 04; 32(2):297-315. Carlberg KT, Singer ST, Vichinsky EP. PMID: 29458733.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    6. Favorable outcomes after in utero transfusion in fetuses with alpha thalassemia major: a case series and review of the literature. Prenat Diagn. 2016 Dec; 36(13):1242-1249. Kreger EM, Singer ST, Witt RG, Sweeters N, Lianoglou B, Lal A, Mackenzie TC, Vichinsky E. PMID: 27862048.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    7. Fertility in transfusion-dependent thalassemia men: effects of iron burden on the reproductive axis. Am J Hematol. 2015 Sep; 90(9):E190-2. Singer ST, Killilea D, Suh JH, Wang ZJ, Yuan Q, Ivani K, Evans P, Vichinsky E, Fischer R, Smith JF. PMID: 26044409; PMCID: PMC4676944.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    8. Elevated tricuspid regurgitant jet velocity in subgroups of thalassemia patients: insight into pathophysiology and the effect of splenectomy. Ann Hematol. 2014 Jul; 93(7):1139-48. Singer ST, Kuypers F, Fineman J, Gildengorin G, Larkin S, Sweeters N, Rosenfeld H, Kurio G, Higa A, Jeng M, Huang J, Vichinsky EP. PMID: 24577514; PMCID: PMC4467727.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    9. Pregnancy outcomes in women with thalassemia in North America and the United Kingdom. Am J Hematol. 2013 Sep; 88(9):771-3. Thompson AA, Kim HY, Singer ST, Vichinsky E, Eile J, Yamashita R, Giardina PJ, Olivieri N, Parmar N, Trachtenberg F, Neufeld EJ, Kwiatkowski JL, Thalassemia Clinical Research Network. PMID: 23757266; PMCID: PMC4106126.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    10. Sildenafil therapy in thalassemia patients with Doppler-defined risk of pulmonary hypertension. Haematologica. 2013 Sep; 98(9):1359-67. Morris CR, Kim HY, Wood J, Porter JB, Klings ES, Trachtenberg FL, Sweeters N, Olivieri NF, Kwiatkowski JL, Virzi L, Singer ST, Taher A, Neufeld EJ, Thompson AA, Sachdev V, Larkin S, Suh JH, Kuypers FA, Vichinsky EP, Thalassemia Clinical Research Network. PMID: 23585527; PMCID: PMC3762091.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCTClinical Trials
    11. Reproductive capacity in iron overloaded women with thalassemia major. Blood. 2011 Sep 08; 118(10):2878-81. Singer ST, Vichinsky EP, Gildengorin G, van Disseldorp J, Rosen M, Cedars MI. PMID: 21757620; PMCID: PMC3172803.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    12. Darbepoetin alfa for the treatment of anaemia in alpha- or beta- thalassaemia intermedia syndromes. Br J Haematol. 2011 Jul; 154(2):281-4. Singer ST, Vichinsky EP, Sweeters N, Rachmilewitz E. PMID: 21496003.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCTClinical Trials
    13. Heterogeneity of hemoglobin H disease in childhood. N Engl J Med. 2011 Feb 24; 364(8):710-8. Lal A, Goldrich ML, Haines DA, Azimi M, Singer ST, Vichinsky EP. PMID: 21345100.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansPHPublic Health
    14. Red cell alloimmunization in a diverse population of transfused patients with thalassaemia. Br J Haematol. 2011 Apr; 153(1):121-8. Thompson AA, Cunningham MJ, Singer ST, Neufeld EJ, Vichinsky E, Yamashita R, Giardina P, Kim HY, Trachtenberg F, Kwiatkowski JL, Thalassemia Clinical Research Network Investigators. PMID: 21323889; PMCID: PMC5728106.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    15. Fertility potential in thalassemia major women: current findings and future diagnostic tools. Ann N Y Acad Sci. 2010 Aug; 1202:226-30. Singer ST, Sweeters N, Vega O, Higa A, Vichinsky E, Cedars M. PMID: 20712797; PMCID: PMC5074539.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    16. Hydroxycarbamide-induced changes in E/beta thalassemia red blood cells. Am J Hematol. 2008 Nov; 83(11):842-5. Singer ST, Vichinsky EP, Larkin S, Olivieri N, Sweeters N, Kuypers FA, E/beta Thalassemia Study Group. PMID: 18821710; PMCID: PMC2881160.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    17. Clinical hemoglobinopathies: iron, lungs and new blood. Curr Opin Hematol. 2006 Nov; 13(6):407-18. Morris CR, Singer ST, Walters MC. PMID: 17053452.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    18. Pulmonary hypertension in thalassemia: association with platelet activation and hypercoagulable state. Am J Hematol. 2006 Sep; 81(9):670-5. Singer ST, Kuypers FA, Styles L, Vichinsky EP, Foote D, Rosenfeld H. PMID: 16795058.
      View in: PubMed   Mentions: 39     Fields:    Translation:Humans
    19. Fetal haemoglobin augmentation in E/beta(0) thalassaemia: clinical and haematological outcome. Br J Haematol. 2005 Nov; 131(3):378-88. Singer ST, Kuypers FA, Olivieri NF, Weatherall DJ, Mignacca R, Coates TD, Davies S, Sweeters N, Vichinsky EP, E/beta Thalassaemia Study Group. PMID: 16225658.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCTClinical Trials
    20. Outcomes of preimplantation genetic diagnosis therapy in treatment of beta-thalassemia: A retrospective analysis. Ann N Y Acad Sci. 2005; 1054:500-3. Qureshi N, Foote D, Walters MC, Singer ST, Quirolo K, Vichinsky EP. PMID: 16339706.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    21. Measuring chromosome breaks in patients with thalassemia. Ann N Y Acad Sci. 2005; 1054:439-44. Offer T, Bhagat A, Lal A, Atamna W, Singer ST, Vichinsky EP, Kuypers FA, Ames BN. PMID: 16339694.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    22. Single and combination drug therapy for fetal hemoglobin augmentation in hemoglobin E-beta 0-thalassemia: Considerations for treatment. Ann N Y Acad Sci. 2005; 1054:250-6. Singer ST, Kuypers FA, Olivieri NF, Weatherall DJ, Mignacca R, Coates TD, Davies S, Sweeters N, Vichinsky EP. PMID: 16339672.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCTClinical Trials
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