I am a hematologist at UCSF Benioff Children’s Hospital Oakland, Director of Clinical Hematology, and Director of the Comprehensive Thalassemia Center and Iron Disorders Program. I spend 50% time in clinic and 50% in research. My long-term academic and clinical interests are thalassemia, iron overload, and nutrition. The Thalassemia Program in Oakland is the largest clinical program in the country managing over 300 active patients. My research portfolio extends from natural history studies, molecular diagnostics, iron quantification, micronutrient deficiencies, to clinical trials in iron chelation, new disease-modifying agents, and gene therapy for beta thalassemia. My center is supported by HRSA and CDC to study the prevalence and complications of thalassemia in the U.S. and to develop evidence-based standards care for thalassemia. I am the coordinator of the Thalassemia Western Consortium, an association of twelve academic hematology programs in the western states, to improve training and management of thalassemia care. Alpha thalassemia is a special emphasis area where we have delineated the genotype-phenotype relationship in alpha thalassemia, published international guidelines for managing HbH disease, postnatal care of alpha thalassemia major. I am invested in the development of gene therapy approaches to severe forms of thalassemia. I provide consultation and care for complex iron overload in non-hematological conditions in children and adults.