David Killilea, PhD

Title(s)MLK Core Manager, Vice Chanc Research
Address5700 Martin Luther King Jr Way, #2708
Oakland CA 94609
ORCID ORCID Icon0000-0002-8929-6527 Additional info
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    Collapse Biography 
    Collapse Education and Training
    Rhodes CollegeB.S.1994Molecular and Cellular Biology
    University of South AlabamaPh.D.2000Pharmacology
    University of California, BerkeleyPost-doctoral2003Molecular and Cellular Biology
    Lawrence Livermore National Laboratory2008Participating Guest Scientist
    University of California, Berkeley2011Visiting Scholar
    University of California, San Francisco, CA2022Diversity, Equity, and Inclusion Champion Training

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Summer Training for Underrepresented and Diverse Youth in STEM (STUDY STEM)
    Doris Duke Charitable Foundation 2023-0361Jan 1, 2024 - Jan 31, 2025
    Role: Co-Investigator
    Supporting Underrepresented Students Adapting to Change: Summer Program to Accelerate Regenerative Medicine Knowledge (SUSTAIN-a-SPARK)
    California Institute for Regenerative Medicine EDUC3-13114Jan 1, 2022 - Dec 31, 2026
    Role: Co-PI
    STIMULUS – Science Technology Immersion for Underrepresented Learners in the US
    NIH/NHLBI 2 R25 HL125451Apr 1, 2021 - Mar 31, 2025
    Role: Co-Investigator
    SSRP Supporting Underrepresented STEM Adapting to Change (SUSTAIN)
    Doris Duke Charitable Foundation 2020241Jan 1, 2021 - Dec 31, 2023
    Role: Co-Investigator
    Determining Optimal Blood Processing and Handling Parameters
    Bill & Melinda Gates Foundation OPP1178834Nov 1, 2018 - Jun 30, 2020
    Role: Principal Investigator
    Clinical Research Continuum: High School to College
    Doris Duke Charitable Foundation 2016143Jan 1, 2017 - Dec 31, 2020
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Increasing STEM Skills, Knowledge and Interest Among Diverse Students: Results from an Intensive Summer Research Program at the University of California, San Francisco. Innovative Higher Education. 2024. Galvez G, Killilea DW, Berry S, Narayanaswami V, and Fung E. View Publication.
    2. Pre-analytical variables influence zinc measurement in blood samples. PLoS One. 2023; 18(9):e0286073. Killilea DW, Schultz K. PMID: 37713369; PMCID: PMC10503700.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    3. Change in Metabolomic Profile Associated with an Average Increase in Plain Water Intake of >+ 1 L/Day, Sustained Over 4 Weeks, in Healthy Young Men with Initial Total Water Intake Below 2 L/Day. Paracelsus Proc Exp Med. 2023; 2(1):41-66. Stookey JD, Paulweber B, Felder TK, Lang F, Häussinger D, Killilea DW, Kuypers FA, Ritter M. PMID: 37304678; PMCID: PMC10253256.
      View in: PubMed   Mentions: 2  
    4. Nutritional Anemia. Nutrition and Health. The Role of Zinc in the Etiology of Anemia. 2022; 187-194. Killilea DW, Siekmann JH. View Publication.
    5. Blood draw site and analytic device influence hemoglobin measurements. PLoS One. 2022; 17(11):e0278350. Killilea DW, Kuypers FA, Larkin SK, Schultz K. PMID: 36449486.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansPHPublic Health
    6. Kidney Stones in Transfusion-Dependent Thalassemia: Prevalence and Risk Factors. Open Journal of Urology. 2022; (12):209-227. Sayani FA, Lal A, Tasian GE, Al Mukaddam M, Killilea DW, Wasserstein A, and Fung EB. View Publication.
    7. Mineral requirements for mitochondrial function: A connection to redox balance and cellular differentiation. Free Radic Biol Med. 2022 03; 182:182-191. Killilea DW, Killilea AN. PMID: 35218912.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    8. Success of Distance Learning During 2020 COVID-19 Restrictions: A Report from Five STEM Training Programs for Underrepresented High School and Undergraduate Learners. J STEM Outreach. 2021; 4(3). Fung EB, Frey MR, Valmont ME, Caffey-Fleming DE, Fraser M, Williams J, Killilea DW, Bogenmann E, Livshits S, Boone DN. PMID: 35252781; PMCID: PMC8896852.
      View in: PubMed   Mentions: 2  
    9. Zinc deficiency and its association with treatment-related toxicity in children with cancer. Pediatr Blood Cancer. 2021 09; 68(9):e29104. Chung JH, Phalke N, Hastings C, Killilea DW, Feusner JH, Fung EB. PMID: 34061438.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Zinc supplementation improves markers of glucose homeostasis in thalassaemia. Br J Haematol. 2020 08; 190(3):e162-e166. Fung EB, Ahmad T, Killilea DW, Hussain R, Lal A. PMID: 32488893.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    11. Plasma and Nail Zinc Concentrations, But Not Hair Zinc, Respond Positively to Two Different Forms of Preventive Zinc Supplementation in Young Laotian Children: a Randomized Controlled Trial. Biol Trace Elem Res. 2021 Feb; 199(2):442-452. Wessells KR, Brown KH, Arnold CD, Barffour MA, Hinnouho GM, Killilea DW, Kounnavong S, Hess SY. PMID: 32356207; PMCID: PMC7746564.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    12. Wheat germ agglutinin is a biomarker of whole grain content in wheat flour and pasta. J Food Sci. 2020 Mar; 85(3):808-815. Killilea DW, McQueen R, Abegania JR. PMID: 32017102.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    13. Oligodendrocyte Death in Pelizaeus-Merzbacher Disease Is Rescued by Iron Chelation. Cell Stem Cell. 2019 Oct 03; 25(4):531-541.e6. Nobuta H, Yang N, Ng YH, Marro SG, Sabeur K, Chavali M, Stockley JH, Killilea DW, Walter PB, Zhao C, Huie P, Goldman SA, Kriegstein AR, Franklin RJM, Rowitch DH, Wernig M. PMID: 31585094; PMCID: PMC8282124.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    14. A conserved role of the insulin-like signaling pathway in diet-dependent uric acid pathologies in Drosophila melanogaster. PLoS Genet. 2019 08; 15(8):e1008318. Lang S, Hilsabeck TA, Wilson KA, Sharma A, Bose N, Brackman DJ, Beck JN, Chen L, Watson MA, Killilea DW, Ho S, Kahn A, Giacomini K, Stoller ML, Chi T, Kapahi P. PMID: 31415568; PMCID: PMC6695094.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    15. Monitoring of the National Oil and Wheat Flour Fortification Program in Cameroon Using a Program Impact Pathway Approach. Curr Dev Nutr. 2019 Aug; 3(8):nzz076. Mark HE, Assiene JG, Luo H, Nankap M, Ndjebayi A, Ngnie-Teta I, Tarini A, Pattar A, Killilea DW, Brown KH, Engle-Stone R. PMID: 31367692; PMCID: PMC6660062.
      View in: PubMed   Mentions: 5  
    16. Early maturing spring wheat in Nordic wildtype NAM-B1 germplasm for short-duration alternative wheat producing regions. Plant Genetic Resources. 2019; 17(4):1-10. Econopouly BF, Van Veldhuizen BM, Lyon SR, Killilea DW, Zhang M, and Jones SS. View Publication.
    17. Potassium restriction boosts vacuolar acidity and extends lifespan in yeast. Exp Gerontol. 2019 06; 120:101-106. Sasikumar AN, Killilea DW, Kennedy BK, Brem RB. PMID: 30742903; PMCID: PMC6568319.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    18. Editorial: Metal Biology Takes Flight: The Study of Metal Homeostasis and Detoxification in Insects. Front Genet. 2018; 9:221. Mohr SE, Killilea DW. PMID: 29971094; PMCID: PMC6018387.
      View in: PubMed   Mentions: 1  
    19. Change in hydration indices associated with an increase in total water intake of more than 0.5 L/day, sustained over 4 weeks, in healthy young men with initial total water intake below 2 L/day. Physiol Rep. 2017 Nov; 5(22). Stookey JD, Hamer J, Killilea DW. PMID: 29150589; PMCID: PMC5704074.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    20. Iron, Zinc, Folate, and Vitamin B-12 Status Increased among Women and Children in Yaoundé and Douala, Cameroon, 1 Year after Introducing Fortified Wheat Flour. J Nutr. 2017 07; 147(7):1426-1436. Engle-Stone R, Nankap M, Ndjebayi AO, Allen LH, Shahab-Ferdows S, Hampel D, Killilea DW, Gimou MM, Houghton LA, Friedman A, Tarini A, Stamm RA, Brown KH. PMID: 28592513; PMCID: PMC5483962.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    21. Flame retardant tris(1,3-dichloro-2-propyl)phosphate (TDCPP) toxicity is attenuated by N-acetylcysteine in human kidney cells. Toxicol Rep. 2017; 4:260-264. Killilea DW, Chow D, Xiao SQ, Li C, Stoller ML. PMID: 28959647; PMCID: PMC5615114.
      View in: PubMed   Mentions: 3  
    22. Identification of a Hemolysis Threshold That Increases Plasma and Serum Zinc Concentration. J Nutr. 2017 06; 147(6):1218-1225. Killilea DW, Rohner F, Ghosh S, Otoo GE, Smith L, Siekmann JH, King JC. PMID: 28490675; PMCID: PMC5443468.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    23. α-Lipoic acid treatment prevents cystine urolithiasis in a mouse model of cystinuria. Nat Med. 2017 Mar; 23(3):288-290. Zee T, Bose N, Zee J, Beck JN, Yang S, Parihar J, Yang M, Damodar S, Hall D, O'Leary MN, Ramanathan A, Gerona RR, Killilea DW, Chi T, Tischfield J, Sahota A, Kahn A, Stoller ML, Kapahi P. PMID: 28165480; PMCID: PMC5656064.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    24. A moderate increase in dietary zinc reduces DNA strand breaks in leukocytes and alters plasma proteins without changing plasma zinc concentrations. Am J Clin Nutr. 2017 02; 105(2):343-351. Zyba SJ, Shenvi SV, Killilea DW, Holland TC, Kim E, Moy A, Sutherland B, Gildengorin V, Shigenaga MK, King JC. PMID: 28003206; PMCID: PMC5267297.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    25. A genome-wide screen of bacterial mutants that enhance dauer formation in C. elegans. Sci Rep. 2016 12 13; 6:38764. Khanna A, Kumar J, Vargas MA, Barrett L, Katewa S, Li P, McCloskey T, Sharma A, Naudé N, Nelson C, Brem R, Killilea DW, Mooney SD, Gill M, Kapahi P. PMID: 27958277; PMCID: PMC5153853.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    26. Dietary Zinc and Incident Calcium Kidney Stones in Adolescence. J Urol. 2017 05; 197(5):1342-1348. Tasian GE, Ross ME, Song L, Grundmeier RW, Massey J, Denburg MR, Copelovitch L, Warner S, Chi T, Killilea DW, Stoller ML, Furth SL. PMID: 27889417; PMCID: PMC5438256.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    27. Zinc Levels Modulate Lifespan through Multiple Longevity Pathways in Caenorhabditis elegans. PLoS One. 2016; 11(4):e0153513. Kumar J, Barhydt T, Awasthi A, Lithgow GJ, Killilea DW, Kapahi P. PMID: 27078872; PMCID: PMC4831763.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    28. Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates ATF4-dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models. Sci Transl Med. 2016 Mar 02; 8(328):328ra29. Karuppagounder SS, Alim I, Khim SJ, Bourassa MW, Sleiman SF, John R, Thinnes CC, Yeh TL, Demetriades M, Neitemeier S, Cruz D, Gazaryan I, Killilea DW, Morgenstern L, Xi G, Keep RF, Schallert T, Tappero RV, Zhong J, Cho S, Maxfield FR, Holman TR, Culmsee C, Fong GH, Su Y, Ming GL, Song H, Cave JW, Schofield CJ, Colbourne F, Coppola G, Ratan RR. PMID: 26936506; PMCID: PMC5341138.
      View in: PubMed   Mentions: 64     Fields:    Translation:AnimalsCells
    29. Acute changes in cellular zinc alters zinc uptake rates prior to zinc transporter gene expression in Jurkat cells. Biometals. 2015 Dec; 28(6):987-96. Holland TC, Killilea DW, Shenvi SV, King JC. PMID: 26420239.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    30. The elementome of calcium-based urinary stones and its role in urolithiasis. Nat Rev Urol. 2015 Oct; 12(10):543-57. Ramaswamy K, Killilea DW, Kapahi P, Kahn AJ, Chi T, Stoller ML. PMID: 26334088; PMCID: PMC4875766.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    31. Fertility in transfusion-dependent thalassemia men: effects of iron burden on the reproductive axis. Am J Hematol. 2015 Sep; 90(9):E190-2. Singer ST, Killilea D, Suh JH, Wang ZJ, Yuan Q, Ivani K, Evans P, Vichinsky E, Fischer R, Smith JF. PMID: 26044409; PMCID: PMC4676944.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    32. Changes in Mineral Micronutrient Status During and After Pulmonary Exacerbation in Adults With Cystic Fibrosis. Nutr Clin Pract. 2015 Dec; 30(6):838-43. Lee MJ, Alvarez JA, Smith EM, Killilea DW, Chmiel JF, Joseph PM, Grossmann RE, Gaggar A, Ziegler TR, Tangpricha V, Vitamin D for Enhancing the Immune System in Cystic Fibrosis Investigators. PMID: 26078287; PMCID: PMC4701694.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    33. Elemental Content of Calcium Oxalate Stones from a Canine Model of Urinary Stone Disease. PLoS One. 2015; 10(6):e0128374. Killilea DW, Westropp JL, Shiraki R, Mellema M, Larsen J, Kahn AJ, Kapahi P, Chi T, Stoller ML. PMID: 26066810; PMCID: PMC4466234.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    34. A Drosophila model identifies a critical role for zinc in mineralization for kidney stone disease. PLoS One. 2015; 10(5):e0124150. Chi T, Kim MS, Lang S, Bose N, Kahn A, Flechner L, Blaschko SD, Zee T, Muteliefu G, Bond N, Kolipinski M, Fakra SC, Mandel N, Miller J, Ramanathan A, Killilea DW, Brückner K, Kapahi P, Stoller ML. PMID: 25970330; PMCID: PMC4430225.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimals
    35. Iron promotes protein insolubility and aging in C. elegans. Aging (Albany NY). 2014 Nov; 6(11):975-91. Klang IM, Schilling B, Sorensen DJ, Sahu AK, Kapahi P, Andersen JK, Swoboda P, Killilea DW, Gibson BW, Lithgow GJ. PMID: 25554795; PMCID: PMC4276790.
      View in: PubMed   Mentions: 31     Fields:    Translation:Animals
    36. Manganese disturbs metal and protein homeostasis in Caenorhabditis elegans. Metallomics. 2014 Oct; 6(10):1816-23. Angeli S, Barhydt T, Jacobs R, Killilea DW, Lithgow GJ, Andersen JK. PMID: 25057947; PMCID: PMC4309368.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    37. Accumulation of metals in GOLD4 COPD lungs is associated with decreased CFTR levels. Respir Res. 2014 Jun 23; 15:69. Hassan F, Xu X, Nuovo G, Killilea DW, Tyrrell J, Da Tan C, Tarran R, Diaz P, Jee J, Knoell D, Boyaka PN, Cormet-Boyaka E. PMID: 24957904; PMCID: PMC4106203.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    38. Stunting prevalence, plasma zinc concentrations, and dietary zinc intakes in a nationally representative sample suggest a high risk of zinc deficiency among women and young children in Cameroon. J Nutr. 2014 Mar; 144(3):382-91. Engle-Stone R, Ndjebayi AO, Nankap M, Killilea DW, Brown KH. PMID: 24453129.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    39. Altered transition metal homeostasis in Niemann-Pick disease, type C1. Metallomics. 2014 Mar; 6(3):542-53. Hung YH, Faux NG, Killilea DW, Yanjanin N, Firnkes S, Volitakis I, Ganio G, Walterfang M, Hastings C, Porter FD, Ory DS, Bush AI. PMID: 24343124; PMCID: PMC4178950.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimals
    40. Zinc deficiency augments leptin production and exacerbates macrophage infiltration into adipose tissue in mice fed a high-fat diet. J Nutr. 2013 Jul; 143(7):1036-45. Liu MJ, Bao S, Bolin ER, Burris DL, Xu X, Sun Q, Killilea DW, Shen Q, Ziouzenkova O, Belury MA, Failla ML, Knoell DL. PMID: 23700340; PMCID: PMC3681543.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    41. ZIP8 regulates host defense through zinc-mediated inhibition of NF-κB. Cell Rep. 2013 Feb 21; 3(2):386-400. Liu MJ, Bao S, Gálvez-Peralta M, Pyle CJ, Rudawsky AC, Pavlovicz RE, Killilea DW, Li C, Nebert DW, Wewers MD, Knoell DL. PMID: 23403290; PMCID: PMC3615478.
      View in: PubMed   Mentions: 153     Fields:    Translation:HumansAnimalsCells
    42. Aluminium exposure disrupts elemental homeostasis in Caenorhabditis elegans. Metallomics. 2012 May; 4(5):512-22. Page KE, White KN, McCrohan CR, Killilea DW, Lithgow GJ. PMID: 22534883; PMCID: PMC3589999.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsPHPublic Health
    43. A connection between magnesium deficiency and aging: new insights from cellular studies. Magnes Res. 2008 Jun; 21(2):77-82. Killilea DW, Maier JA. PMID: 18705534; PMCID: PMC2790427.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    44. Magnesium deficiency accelerates cellular senescence in cultured human fibroblasts. Proc Natl Acad Sci U S A. 2008 Apr 15; 105(15):5768-73. Killilea DW, Ames BN. PMID: 18391207; PMCID: PMC2311331.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    45. Lipoic acid and acetyl-carnitine reverse iron-induced oxidative stress in human fibroblasts. Redox Rep. 2008; 13(1):2-10. Lal A, Atamna W, Killilea DW, Suh JH, Ames BN. PMID: 18284845.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    46. Pharmacogenetic analysis of lithium-induced delayed aging in Caenorhabditis elegans. J Biol Chem. 2008 Jan 04; 283(1):350-357. McColl G, Killilea DW, Hubbard AE, Vantipalli MC, Melov S, Lithgow GJ. PMID: 17959600; PMCID: PMC2739662.
      View in: PubMed   Mentions: 102     Fields:    Translation:HumansAnimalsCells
    47. Zinc deficiency reduces paclitaxel efficacy in LNCaP prostate cancer cells. Cancer Lett. 2007 Dec 08; 258(1):70-9. Killilea AN, Downing KH, Killilea DW. PMID: 17905512.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    48. N-tert-butyl hydroxylamine, a mitochondrial antioxidant, protects human retinal pigment epithelial cells from iron overload: relevance to macular degeneration. FASEB J. 2007 Dec; 21(14):4077-86. Voloboueva LA, Killilea DW, Atamna H, Ames BN. PMID: 17656467; PMCID: PMC2597693.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    49. Steady-state asymmetric nanospray dual ion source for accurate mass determination within a chromatographic separation. Anal Chem. 2007 Aug 01; 79(15):5711-8. Young NL, Sisto MC, Young MN, Grant PG, Killilea DW, LaMotte L, Wu KJ, Lebrilla CB. PMID: 17614364; PMCID: PMC2597711.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    50. Dialyzability of minerals in corn masa gruel (atole) fortified with different iron compounds: effects of ascorbic acid, disodium EDTA, and phytic acid. Food Nutr Bull. 2007 Jun; 28(2):198-205. De-Regil LM, Casanueva E, Killilea DW, Viteri FE. PMID: 24683679.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    51. Oxidative stress and inflammation in iron-overloaded patients with beta-thalassaemia or sickle cell disease. Br J Haematol. 2006 Oct; 135(2):254-63. Walter PB, Fung EB, Killilea DW, Jiang Q, Hudes M, Madden J, Porter J, Evans P, Vichinsky E, Harmatz P. PMID: 17010049; PMCID: PMC2185791.
      View in: PubMed   Mentions: 92     Fields:    Translation:Humans
    52. Mineral and vitamin deficiencies can accelerate the mitochondrial decay of aging. Mol Aspects Med. 2005 Aug-Oct; 26(4-5):363-78. Ames BN, Atamna H, Killilea DW. PMID: 16102804.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    53. Iron accumulation during cellular senescence. Ann N Y Acad Sci. 2004 Jun; 1019:365-7. Killilea DW, Wong SL, Cahaya HS, Atamna H, Ames BN. PMID: 15247045.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    54. Iron accumulation during cellular senescence in human fibroblasts in vitro. Antioxid Redox Signal. 2003 Oct; 5(5):507-16. Killilea DW, Atamna H, Liao C, Ames BN. PMID: 14580305; PMCID: PMC4503765.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    55. Heme deficiency may be a factor in the mitochondrial and neuronal decay of aging. Proc Natl Acad Sci U S A. 2002 Nov 12; 99(23):14807-12. Atamna H, Killilea DW, Killilea AN, Ames BN. PMID: 12417755; PMCID: PMC137500.
      View in: PubMed   Mentions: 71     Fields:    Translation:HumansAnimalsCells
    56. Age-associated mitochondrial oxidative decay: improvement of carnitine acetyltransferase substrate-binding affinity and activity in brain by feeding old rats acetyl-L- carnitine and/or R-alpha -lipoic acid. Proc Natl Acad Sci U S A. 2002 Feb 19; 99(4):1876-81. Liu J, Killilea DW, Ames BN. PMID: 11854488; PMCID: PMC122287.
      View in: PubMed   Mentions: 75     Fields:    Translation:AnimalsCells
    57. Hypoxia promotes oxidative base modifications in the pulmonary artery endothelial cell VEGF gene. FASEB J. 2001 May; 15(7):1267-9. Grishko V, Solomon M, Breit JF, Killilea DW, Ledoux SP, Wilson GL, Gillespie MN. PMID: 11344109.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    58. Free radical production in hypoxic pulmonary artery smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 2000 Aug; 279(2):L408-12. Killilea DW, Hester R, Balczon R, Babal P, Gillespie MN. PMID: 10926565.
      View in: PubMed   Mentions: 30     Fields:    Translation:Animals
    59. Hypoxia causes oxidant lesions in the rat pulmonary artery smooth muscle cell VEGF gene: potential link to VEGF mRNA expression. Chest. 1998 Jul; 114(1 Suppl):45S. Gillespie MN, Killilea DW, Solomon M, Babal P, LeDoux SP, Wilson GL. PMID: 9676623.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    60. Erythro-9-(2-hydroxy-3-nonyl)adenine inhibits cyclic-3',5'-guanosine monophosphate-stimulated phosphodiesterase to reverse hypoxic pulmonary vasoconstriction in the perfused rat lung. J Pharmacol Exp Ther. 1996 Feb; 276(2):752-7. Haynes J, Killilea DW, Peterson PD, Thompson WJ. PMID: 8632346.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
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