Michael Burgess | UCSF Profiles

Michael Burgess, MD, PhD

Title	Assistant Clinical Professor
Institution	University of California San Francisco
Department	Medicine
Address	995 Potrero Ave WARD 86 San Francisco CA 94110
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Biography

Education and Training

University of California, San Francisco	Fellowship	2012	Hematology and Medical Oncology
University of California, San Francisco	Residency	2009	Internal Medicine
David Geffen School of Medicine at UCLA	M.D.	2007	Medicine
University of California, Los Angeles	Ph.D.	2005	Molecular Biology
University of California, Berkeley	B.A.	1997	Molecular and Cell Biology

Overview

Interests

Acute Myeloid Leukemia, Myelodysplastic Syndromes, Early Clinical Development, Biomarker Discovery

Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.

List All | Timeline

An N, Khan S, Imgruet MK, Gurbuxani SK, Konecki SN, Burgess M, McNerney ME. Gene dosage effect of CUX1 in a murine model disrupts HSC homeostasis and controls the severity and mortality of MDS. Blood. 2018 Mar 28. PMID: 29592892.

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Burgess M, Hwang E, Mroue R, Bielski CM, Wandler AM, Huang BJ, Firestone AJ, Young A, Lacap JA, Crocker L, Asthana S, Davis EM, Xu J, Akagi K, Le Beau MM, Li Q, Haley B, Stokoe D, Sampath D, Taylor BS, Evangelista M, Shannon K. KRAS Allelic Imbalance Enhances Fitness and Modulates MAP Kinase Dependence in Cancer. Cell. 2017 Feb 23; 168(5):817-829.e15. PMID: 28215705.

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Fenouille N, Bassil CF, Ben-Sahra I, Benajiba L, Alexe G, Ramos A, Pikman Y, Conway AS, Burgess M, Li Q, Luciano F, Auberger P, Galinsky I, DeAngelo DJ, Stone RM, Zhang Y, Perkins AS, Shannon K, Hemann MT, Puissant A, Stegmaier K. The creatine kinase pathway is a metabolic vulnerability in EVI1-positive acute myeloid leukemia. Nat Med. 2017 Mar; 23(3):301-313. PMID: 28191887.

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Wong JC, Weinfurtner KM, Alzamora Mdel P, Kogan SC, Burgess M, Zhang Y, Nakitandwe J, Ma J, Cheng J, Chen SC, Ho TT, Flach J, Reynaud D, Passegué E, Downing JR, Shannon K. Functional evidence implicating chromosome 7q22 haploinsufficiency in myelodysplastic syndrome pathogenesis. Elife. 2015 Jul 20; 4. PMID: 26193121; PMCID: PMC4569895.

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Burgess M, Hwang E, Firestone AJ, Huang T, Xu J, Zuber J, Bohin N, Wen T, Kogan SC, Haigis KM, Sampath D, Lowe S, Shannon K, Li Q. Preclinical efficacy of MEK inhibition in Nras-mutant AML. Blood. 2014 Dec 18; 124(26):3947-55. PMID: 25361812; PMCID: PMC4271180.

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Balbas MD, Burgess M, Murali R, Wongvipat J, Skaggs BJ, Mundel P, Weins A, Sawyers CL. MAGI-2 scaffold protein is critical for kidney barrier function. Proc Natl Acad Sci U S A. 2014 Oct 14; 111(41):14876-81. PMID: 25271328; PMCID: PMC4205655.

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Diaz-Flores E, Goldschmidt H, Depeille P, Ng V, Akutagawa J, Krisman K, Crone M, Burgess M, Williams O, Houseman B, Shokat K, Sampath D, Bollag G, Roose JP, Braun BS, Shannon K. PLC-? and PI3K link cytokines to ERK activation in hematopoietic cells with normal and oncogenic Kras. Sci Signal. 2013 Dec 03; 6(304):ra105. PMID: 24300897; PMCID: PMC4117477.

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Skaggs BJ, Gorre ME, Ryvkin A, Burgess M, Xie Y, Han Y, Komisopoulou E, Brown LM, Loo JA, Landaw EM, Sawyers CL, Graeber TG. Phosphorylation of the ATP-binding loop directs oncogenicity of drug-resistant BCR-ABL mutants. Proc Natl Acad Sci U S A. 2006 Dec 19; 103(51):19466-71. PMID: 17164333; PMCID: PMC1698443.

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Burgess M, Sawyers CL. Treating imatinib-resistant leukemia: the next generation targeted therapies. ScientificWorldJournal. 2006 Aug 11; 6:918-30. PMID: 16906325.

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Burgess M, Skaggs BJ, Shah NP, Lee FY, Sawyers CL. Comparative analysis of two clinically active BCR-ABL kinase inhibitors reveals the role of conformation-specific binding in resistance. Proc Natl Acad Sci U S A. 2005 Mar 01; 102(9):3395-400. PMID: 15705718; PMCID: PMC552942.

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