 Paola Betancur, PhD
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| Title(s) | Assistant Professor, Radiation Oncology |
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| School | School of Medicine |
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| Address | 1600 Divisadero
San Francisco CA 94115
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| Phone | 415-514-1084 |
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| vCard | Download vCard |
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 Biography | University of California San Francisco, CA | | 2020 | Diversity, Equity and Inclusion Champion Training | | Stanford University, CA | Post-doctoral fellowship | 2017 | Cancer Immunology | | California Institute of Technology, CA | PhD | 2010 | Cell Biology | | Stony Brook University, NY | BS | 2003 | Biology |
Overview We are interested in understanding the mechanisms encoded in the DNA by which cancerous cells avoid being detected and destroyed by the host’s immune system. Toward this goal, we examine the interactions between epigenetic modifiers, transcription factors and the genomic enhancers of target genes that in response to inflammation abnormally activate the immune escape program within tumor or damaged cells during aging, after radiation and in response to infectious diseases. To accomplish our goal, we have long lasting collaborations across campus, at Stanford University and other recognized national and international institutions.
With patients in mind, we are a research group dedicated to finding methods for improving the treatment of cancer by analyzing the DNA of individual patients. In the era of personalized medicine, this information is critical for understanding which therapy will be more effective for each patient, and for targeting specific cancer types, including cancer of the breast.
Research ORNG Applications Bibliographic
Altmetrics Details
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media.
(Note that publications are often cited in additional ways that are not shown here.)
Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
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Activation of JUN in fibroblasts promotes pro-fibrotic programme and modulates protective immunity. Nat Commun. 2020 06 03; 11(1):2795.
Cui L, Chen SY, Lerbs T, Lee JW, Domizi P, Gordon S, Kim YH, Nolan G, Betancur P, Wernig G. PMID: 32493933.
View in: PubMed Mentions: 3 Fields: Translation: HumansAnimalsCells
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A CD47-associated super-enhancer links pro-inflammatory signalling to CD47 upregulation in breast cancer. Nat Commun. 2017 04 05; 8:14802.
Betancur PA, Abraham BJ, Yiu YY, Willingham SB, Khameneh F, Zarnegar M, Kuo AH, McKenna K, Kojima Y, Leeper NJ, Ho P, Gip P, Swigut T, Sherwood RI, Clarke MF, Somlo G, Young RA, Weissman IL. PMID: 28378740.
View in: PubMed Mentions: 33 Fields: Translation: HumansAnimalsCells
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CD47-blocking antibodies restore phagocytosis and prevent atherosclerosis. Nature. 2016 08 04; 536(7614):86-90.
Kojima Y, Volkmer JP, McKenna K, Civelek M, Lusis AJ, Miller CL, Direnzo D, Nanda V, Ye J, Connolly AJ, Schadt EE, Quertermous T, Betancur P, Maegdefessel L, Matic LP, Hedin U, Weissman IL, Leeper NJ. PMID: 27437576.
View in: PubMed Mentions: 92 Fields: Translation: HumansAnimalsCells
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Expression and function of transcription factor cMyb during cranial neural crest development. Mech Dev. 2014 May; 132:38-43.
Betancur P, Simões-Costa M, Sauka-Spengler T, Bronner ME. PMID: 24509349.
View in: PubMed Mentions: 3 Fields: Translation: Animals
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A Sox10 enhancer element common to the otic placode and neural crest is activated by tissue-specific paralogs. Development. 2011 Sep; 138(17):3689-98.
Betancur P, Sauka-Spengler T, Bronner M. PMID: 21775416.
View in: PubMed Mentions: 21 Fields: Translation: AnimalsCells
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Genomic code for Sox10 activation reveals a key regulatory enhancer for cranial neural crest. Proc Natl Acad Sci U S A. 2010 Feb 23; 107(8):3570-5.
Betancur P, Bronner-Fraser M, Sauka-Spengler T. PMID: 20139305.
View in: PubMed Mentions: 66 Fields: Translation: HumansAnimalsCells
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Assembling neural crest regulatory circuits into a gene regulatory network. Annu Rev Cell Dev Biol. 2010; 26:581-603.
Betancur P, Bronner-Fraser M, Sauka-Spengler T. PMID: 19575671.
View in: PubMed Mentions: 103 Fields: Translation: Animals
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c-Myb, Ets-1 and Sox9 directly activate a Sox10 core enhancer in delaminating cranial neural crest. Developmental Biology. 2009 Jul 1; 331(2):438.
Paola A. Betancur, Tatjana Sauka-Spengler, Marianne Bronner-Fraser. .
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| Year | Publications |
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| 2009 | 1 | | 2010 | 2 | | 2011 | 1 | | 2014 | 1 | | 2016 | 1 | | 2017 | 1 | | 2020 | 1 |
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This graph shows the number and percent of publications by field.
Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications.
Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written.
To see the data as text, click here.
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