Paola Betancur * UCSF Profiles

Paola Betancur, PhD

Title(s)	Assistant Professor, Radiation Oncology
School	School of Medicine
Phone	415-514-1084
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Research

Research Activities and Funding

Identification of Novel Gene Regulatory Interactions Driving the Immune Evasion Program Through Transcriptional Activation of CD47 in Cancer
NIH/NCI K22CA226365Sep 1, 2019 - Aug 31, 2022
Role: Principal Investigator

Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.

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Betancur PA, Abraham BJ, Yiu YY, Willingham SB, Khameneh F, Zarnegar M, Kuo AH, McKenna K, Kojima Y, Leeper NJ, Ho P, Gip P, Swigut T, Sherwood RI, Clarke MF, Somlo G, Young RA, Weissman IL. A CD47-associated super-enhancer links pro-inflammatory signalling to CD47 upregulation in breast cancer. Nat Commun. 2017 04 05; 8:14802. PMID: 28378740.

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Kojima Y, Volkmer JP, McKenna K, Civelek M, Lusis AJ, Miller CL, Direnzo D, Nanda V, Ye J, Connolly AJ, Schadt EE, Quertermous T, Betancur P, Maegdefessel L, Matic LP, Hedin U, Weissman IL, Leeper NJ. CD47-blocking antibodies restore phagocytosis and prevent atherosclerosis. Nature. 2016 08 04; 536(7614):86-90. PMID: 27437576.

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Betancur P, Simões-Costa M, Sauka-Spengler T, Bronner ME. Expression and function of transcription factor cMyb during cranial neural crest development. Mech Dev. 2014 May; 132:38-43. PMID: 24509349.

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Betancur P, Sauka-Spengler T, Bronner M. A Sox10 enhancer element common to the otic placode and neural crest is activated by tissue-specific paralogs. Development. 2011 Sep; 138(17):3689-98. PMID: 21775416.

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Betancur P, Bronner-Fraser M, Sauka-Spengler T. Genomic code for Sox10 activation reveals a key regulatory enhancer for cranial neural crest. Proc Natl Acad Sci U S A. 2010 Feb 23; 107(8):3570-5. PMID: 20139305.

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Betancur P, Bronner-Fraser M, Sauka-Spengler T. Assembling neural crest regulatory circuits into a gene regulatory network. Annu Rev Cell Dev Biol. 2010; 26:581-603. PMID: 19575671.

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Paola A. Betancur, Tatjana Sauka-Spengler, Marianne Bronner-Fraser. c-Myb, Ets-1 and Sox9 directly activate a Sox10 core enhancer in delaminating cranial neural crest. Developmental Biology. 2009 Jul 1; 331(2):438.

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