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Nadav Ahituv, PhD

Title(s)Professor, Bioengineering
SchoolSchool of Pharmacy
Address1550 Fourth St
San Francisco CA 94158
Phone415-476-1838
ORCID ORCID Icon0000-0002-7434-8144 Additional info
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    Collapse Biography 
    Collapse Awards and Honors
    Tel-Aviv University2002  - 2002Ph.D. with distinction
    The American Society for Clinical Pharmacology and Therapeutics2014  - 2014ASCPT Leon I. Goldberg young investigator award

    Collapse Overview 
    Collapse Overview
    The Ahituv lab is focused on understanding the role of regulatory sequences in human biology and disease. Through a combination of comparative genomic strategies, biochemical assays, regulatory element analysis, human patient samples, mouse and fish genetic engineering technologies, and massively parallel reporter assays they are working to elucidate mechanisms whereby genetic variation within these sequences lead to changes in human phenotypes.

    Collapse Research 
    Collapse Research Activities and Funding
    From Obesity GWAS to therapeutic targets
    NIH/NIDDK R01DK124769Jul 1, 2020 - Jun 30, 2025
    Role: Co-Principal Investigator
    Technologies for simultaneous characterization of regulatory activity and protein binding
    NIH/NHGRI R21HG010683Aug 16, 2019 - Jul 31, 2021
    Role: Principal Investigator
    Genetic Etiology of Abdominal Hernia Susceptibility
    NIH/NIDDK R01DK116738Sep 15, 2018 - Aug 31, 2021
    Role: Co-Principal Investigator
    Massively parallel reporter assays and genome editing of ENCODE predicted regulatory elements
    NIH/NHGRI UM1HG009408Aug 14, 2018 - Jan 31, 2021
    Role: Principal Investigator
    Massively parallel characterization of psychiatric disease associated regulatory elements in defined cell types
    NIH/NIMH U01MH116438Jul 6, 2018 - Mar 31, 2023
    Role: Principal Investigator
    Development of massively parallel reporter assays that use cognate promoters
    NIH/NHGRI R21HG010065May 1, 2018 - Apr 30, 2020
    Role: Co-Principal Investigator
    Developmental Mechanisms of Human Idiopathic Scoliosis
    NIH/NICHD P01HD084387Sep 1, 2016 - Jun 30, 2021
    Role: Co-Principal Investigator
    Massively parallel dissection of psychiatric regulatory networks
    NIH/NIMH R01MH109907May 1, 2016 - Feb 28, 2021
    Role: Co-Principal Investigator
    The Airway Functional Genomics of Bronchodilator Drug Response in Minority Children with Asthma
    NIH/NHLBI R01HL117004Aug 1, 2013 - Jun 30, 2023
    Role: Co-Principal Investigator
    Identification &functional characterization of SIM1 obesity-associated variants
    NIH/NIDDK R01DK090382May 1, 2012 - Mar 31, 2016
    Role: Co-Principal Investigator
    Massively parallel, in vivo functional testing of regulatory elements
    NIH/NHGRI R01HG006768Apr 24, 2012 - Feb 28, 2015
    Role: Co-Principal Investigator
    Characterization of neuronal gene regulatory elements associated with epilepsy
    NIH/NINDS R01NS079231Apr 1, 2012 - Mar 31, 2016
    Role: Principal Investigator
    Computational &Functional Annotation of the Zebrafish Genome Regulatory Toolbox
    NIH/NHGRI R01HG005058Sep 29, 2009 - Jul 31, 2014
    Role: Co-Principal Investigator
    Characterization of regulatory elements leading to human limb malformations
    NIH/NICHD R01HD059862Apr 1, 2009 - Mar 31, 2014
    Role: Principal Investigator
    Pharmacogenomics of Membrane Transporters
    NIH U19GM061390Apr 1, 2000 - Jun 30, 2015
    Role: Co-Investigator
    Pharmaceutical Sciences and Pharmacogenomics
    NIH/NIGMS T32GM007175Jul 1, 1982 - Jun 30, 2022
    Role: Co-Principal Investigator

    Collapse ORNG Applications 
    Collapse Websites
    Collapse Student Projects
    Collapse Academic Senate

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Co-option of the lineage-specific LAVA retrotransposon in the gibbon genome. Proc Natl Acad Sci U S A. 2020 Jul 20. Okhovat M, Nevonen KA, Davis BA, Michener P, Ward S, Milhaven M, Harshman L, Sohota A, Fernandes JD, Salama SR, O'Neill RJ, Ahituv N, Veeramah KR, Carbone L. PMID: 32690705.
      View in: PubMed   Mentions:    Fields:    
    2. lentiMPRA and MPRAflow for high-throughput functional characterization of gene regulatory elements. Nat Protoc. 2020 Jul 08. Gordon MG, Inoue F, Martin B, Schubach M, Agarwal V, Whalen S, Feng S, Zhao J, Ashuach T, Ziffra R, Kreimer A, Georgakopoulous-Soares I, Yosef N, Ye CJ, Pollard KS, Shendure J, Kircher M, Ahituv N. PMID: 32641802.
      View in: PubMed   Mentions:    Fields:    
    3. Noncoding SNPs associated with increased GDF15 levels located in a metformin-activated enhancer region upstream of GDF15. Pharmacogenomics. 2020 06; 21(8):509-520. Linhares ND, Pereira DA, Conceição IM, Franco GR, Eckalbar WL, Ahituv N, Luizon MR. PMID: 32427048.
      View in: PubMed   Mentions:    Fields:    
    4. The cartilage matrisome in adolescent idiopathic scoliosis. Bone Res. 2020; 8:13. Wise CA, Sepich D, Ushiki A, Khanshour AM, Kidane YH, Makki N, Gurnett CA, Gray RS, Rios JJ, Ahituv N, Solnica-Krezel L. PMID: 32195011.
      View in: PubMed   Mentions:
    5. Characterization of functional transposable element enhancers in acute myeloid leukemia. Sci China Life Sci. 2020 May; 63(5):675-687. Zeng Y, Cao Y, Halevy RS, Nguyen P, Liu D, Zhang X, Ahituv N, Han JJ. PMID: 32170627.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    6. Comparative Genomic Characterization of the Multimammate Mouse Mastomys coucha. Mol Biol Evol. 2019 12 01; 36(12):2805-2812. Hardin A, Nevonen KA, Eckalbar WL, Carbone L, Ahituv N. PMID: 31424545.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    7. Dysregulation of STAT3 signaling is associated with endplate-oriented herniations of the intervertebral disc in Adgrg6 mutant mice. PLoS Genet. 2019 10; 15(10):e1008096. Liu Z, Easson GWD, Zhao J, Makki N, Ahituv N, Hilton MJ, Tang SY, Gray RS. PMID: 31652254.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    8. Identification and Massively Parallel Characterization of Regulatory Elements Driving Neural Induction. Cell Stem Cell. 2019 Nov 07; 25(5):713-727.e10. Inoue F, Kreimer A, Ashuach T, Ahituv N, Yosef N. PMID: 31631012.
      View in: PubMed   Mentions: 1     Fields:    
    9. MPRAnalyze: statistical framework for massively parallel reporter assays. Genome Biol. 2019 09 02; 20(1):183. Ashuach T, Fischer DS, Kreimer A, Ahituv N, Theis FJ, Yosef N. PMID: 31477158.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    10. A novel ZRS variant causes preaxial polydactyly type I by increased sonic hedgehog expression in the developing limb bud. Genet Med. 2020 01; 22(1):189-198. Xu C, Yang X, Zhou H, Li Y, Xing C, Zhou T, Zhong D, Lian C, Yan M, Chen T, Liao Z, Gao B, Su D, Wang T, Sharma S, Mohan C, Ahituv N, Malik S, Li QZ, Su P. PMID: 31395945.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    11. Saturation mutagenesis of twenty disease-associated regulatory elements at single base-pair resolution. Nat Commun. 2019 08 08; 10(1):3583. Kircher M, Xiong C, Martin B, Schubach M, Inoue F, Bell RJA, Costello JF, Shendure J, Ahituv N. PMID: 31395865.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    12. Integration of multiple epigenomic marks improves prediction of variant impact in saturation mutagenesis reporter assay. Hum Mutat. 2019 09; 40(9):1280-1291. Shigaki D, Adato O, Adhikari AN, Dong S, Hawkins-Hooker A, Inoue F, Juven-Gershon T, Kenlay H, Martin B, Patra A, Penzar DD, Schubach M, Xiong C, Yan Z, Boyle AP, Kreimer A, Kulakovskiy IV, Reid J, Unger R, Yosef N, Shendure J, Ahituv N, Kircher M, Beer MA. PMID: 31106481.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    13. Meta-analysis of massively parallel reporter assays enables prediction of regulatory function across cell types. Hum Mutat. 2019 09; 40(9):1299-1313. Kreimer A, Yan Z, Ahituv N, Yosef N. PMID: 31131957.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    14. Genomic and epigenomic mapping of leptin-responsive neuronal populations involved in body weight regulation. Nat Metab. 2019 Apr; 1(4):475-484. Inoue F, Eckalbar WL, Wang Y, Murphy KK, Matharu N, Vaisse C, Ahituv N. PMID: 31535083.
      View in: PubMed   Mentions:
    15. A Genome-wide Framework for Mapping Gene Regulation via Cellular Genetic Screens. Cell. 2019 Mar 07; 176(6):1516. Gasperini M, Hill AJ, McFaline-Figueroa JL, Martin B, Kim S, Zhang MD, Jackson D, Leith A, Schreiber J, Noble WS, Trapnell C, Ahituv N, Shendure J. PMID: 30849375.
      View in: PubMed   Mentions: 1     Fields:    
    16. Reply to Liu et al.: Tissue specificity of SIM1 gene expression and erectile dysfunction. Proc Natl Acad Sci U S A. 2019 02 26; 116(9):3349-3350. Jorgenson E, Matharu N, Palmer MR, Yin J, Shan J, Hoffmann TJ, Thai KK, Zhou X, Hotaling JM, Jarvik GP, Ahituv N, Wessells H, Van Den Eeden SK. PMID: 30755537.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    17. A Genome-wide Framework for Mapping Gene Regulation via Cellular Genetic Screens. Cell. 2019 01 10; 176(1-2):377-390.e19. Gasperini M, Hill AJ, McFaline-Figueroa JL, Martin B, Kim S, Zhang MD, Jackson D, Leith A, Schreiber J, Noble WS, Trapnell C, Ahituv N, Shendure J. PMID: 30612741.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    18. Genome-wide de novo risk score implicates promoter variation in autism spectrum disorder. Science. 2018 12 14; 362(6420). An JY, Lin K, Zhu L, Werling DM, Dong S, Brand H, Wang HZ, Zhao X, Schwartz GB, Collins RL, Currall BB, Dastmalchi C, Dea J, Duhn C, Gilson MC, Klei L, Liang L, Markenscoff-Papadimitriou E, Pochareddy S, Ahituv N, Buxbaum JD, Coon H, Daly MJ, Kim YS, Marth GT, Neale BM, Quinlan AR, Rubenstein JL, Sestan N, State MW, Willsey AJ, Talkowski ME, Devlin B, Roeder K, Sanders SJ. PMID: 30545852.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    19. CRISPR-mediated activation of a promoter or enhancer rescues obesity caused by haploinsufficiency. Science. 2019 01 18; 363(6424). Matharu N, Rattanasopha S, Tamura S, Maliskova L, Wang Y, Bernard A, Hardin A, Eckalbar WL, Vaisse C, Ahituv N. PMID: 30545847.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    20. Genome-wide meta-analysis and replication studies in multiple ethnicities identify novel adolescent idiopathic scoliosis susceptibility loci. Hum Mol Genet. 2018 11 15; 27(22):3986-3998. Khanshour AM, Kou I, Fan Y, Einarsdottir E, Makki N, Kidane YH, Kere J, Grauers A, Johnson TA, Paria N, Patel C, Singhania R, Kamiya N, Takeda K, Otomo N, Watanabe K, Luk KDK, Cheung KMC, Herring JA, Rios JJ, Ahituv N, Gerdhem P, Gurnett CA, Song YQ, Ikegawa S, Wise CA. PMID: 30395268.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    21. A multidisciplinary review of triphalangeal thumb. J Hand Surg Eur Vol. 2019 Jan; 44(1):59-68. Potuijt JWP, Galjaard RH, van der Spek PJ, van Nieuwenhoven CA, Ahituv N, Oberg KC, Hovius SER. PMID: 30318985.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    22. Genetic variation in the SIM1 locus is associated with erectile dysfunction. Proc Natl Acad Sci U S A. 2018 10 23; 115(43):11018-11023. Jorgenson E, Matharu N, Palmer MR, Yin J, Shan J, Hoffmann TJ, Thai KK, Zhou X, Hotaling JM, Jarvik GP, Ahituv N, Wessells H, Van Den Eeden SK. PMID: 30297428.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    23. Whole-Genome Sequencing of Pharmacogenetic Drug Response in Racially Diverse Children with Asthma. Am J Respir Crit Care Med. 2018 06 15; 197(12):1552-1564. Mak ACY, White MJ, Eckalbar WL, Szpiech ZA, Oh SS, Pino-Yanes M, Hu D, Goddard P, Huntsman S, Galanter J, Wu AC, Himes BE, Germer S, Vogel JM, Bunting KL, Eng C, Salazar S, Keys KL, Liberto J, Nuckton TJ, Nguyen TA, Torgerson DG, Kwok PY, Levin AM, Celedón JC, Forno E, Hakonarson H, Sleiman PM, Dahlin A, Tantisira KG, Weiss ST, Serebrisky D, Brigino-Buenaventura E, Farber HJ, Meade K, Lenoir MA, Avila PC, Sen S, Thyne SM, Rodriguez-Cintron W, Winkler CA, Moreno-Estrada A, Sandoval K, Rodriguez-Santana JR, Kumar R, Williams LK, Ahituv N, Ziv E, Seibold MA, Darnell RB, Zaitlen N, Hernandez RD, Burchard EG. PMID: 29509491.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    24. Corrigendum: A systematic comparison reveals substantial differences in chromosomal versus episomal encoding of enhancer activity. Genome Res. 2018 05; 28(5):766.3. Inoue F, Kircher M, Martin B, Cooper GM, Witten DM, McManus MT, Ahituv N, Shendure J. PMID: 29717003.
      View in: PubMed   Mentions:    Fields:    
    25. Mutations in the fourth ß-propeller domain of LRP4 are associated with isolated syndactyly with fusion of the third and fourth fingers. Hum Mutat. 2018 06; 39(6):811-815. Sukenik Halevy R, Chien HC, Heinz B, Bamshad MJ, Nickerson DA, Kircher M, Ahituv N. PMID: 29524275.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    26. A point mutation in the pre-ZRS disrupts sonic hedgehog expression in the limb bud and results in triphalangeal thumb-polysyndactyly syndrome. Genet Med. 2018 11; 20(11):1405-1413. Potuijt JWP, Baas M, Sukenik-Halevy R, Douben H, Nguyen P, Venter DJ, Gallagher R, Swagemakers SM, Hovius SER, van Nieuwenhoven CA, Galjaard RH, van der Spek PJ, Ahituv N, de Klein A. PMID: 29543231.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    27. Rare Variants in the ABCG2 Promoter Modulate In Vivo Activity. Drug Metab Dispos. 2018 05; 46(5):636-642. Eclov RJ, Kim MJ, Smith R, Ahituv N, Kroetz DL. PMID: 29467213.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    28. ABCG2 regulatory single-nucleotide polymorphisms alter in vivo enhancer activity and expression. Pharmacogenet Genomics. 2017 Dec; 27(12):454-463. Eclov RJ, Kim MJ, Chhibber A, Smith RP, Ahituv N, Kroetz DL. PMID: 28930109.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    29. CRISPR-Cas9-mediated functional dissection of 3'-UTRs. Nucleic Acids Res. 2017 Oct 13; 45(18):10800-10810. Zhao W, Siegel D, Biton A, Tonqueze OL, Zaitlen N, Ahituv N, Erle DJ. PMID: 28985357.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    30. Variant Interpretation: Functional Assays to the Rescue. Am J Hum Genet. 2017 Sep 07; 101(3):315-325. Starita LM, Ahituv N, Dunham MJ, Kitzman JO, Roth FP, Seelig G, Shendure J, Fowler DM. PMID: 28886340.
      View in: PubMed   Mentions: 34     Fields:    Translation:Humans
    31. Use antibiotics in cell culture with caution: genome-wide identification of antibiotic-induced changes in gene expression and regulation. Sci Rep. 2017 08 08; 7(1):7533. Ryu AH, Eckalbar WL, Kreimer A, Yosef N, Ahituv N. PMID: 28790348.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    32. Gene Regulatory Elements, Major Drivers of Human Disease. Annu Rev Genomics Hum Genet. 2017 08 31; 18:45-63. Chatterjee S, Ahituv N. PMID: 28399667.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    33. Limb development: a paradigm of gene regulation. Nat Rev Genet. 2017 04; 18(4):245-258. Petit F, Sears KE, Ahituv N. PMID: 28163321.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    34. Genomic Characterization of Metformin Hepatic Response. PLoS Genet. 2016 Nov; 12(11):e1006449. Luizon MR, Eckalbar WL, Wang Y, Jones SL, Smith RP, Laurance M, Lin L, Gallins PJ, Etheridge AS, Wright F, Zhou Y, Molony C, Innocenti F, Yee SW, Giacomini KM, Ahituv N. PMID: 27902686.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    35. In Vivo Hepatic Enhancer Elements in the Human ABCG2 Locus. Drug Metab Dispos. 2017 02; 45(2):208-215. Eclov RJ, Kim MJ, Smith RP, Liang X, Ahituv N, Kroetz DL. PMID: 27856528.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    36. A systematic comparison reveals substantial differences in chromosomal versus episomal encoding of enhancer activity. Genome Res. 2017 01; 27(1):38-52. Inoue F, Kircher M, Martin B, Cooper GM, Witten DM, McManus MT, Ahituv N, Shendure J. PMID: 27831498.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    37. Bat Accelerated Regions Identify a Bat Forelimb Specific Enhancer in the HoxD Locus. PLoS Genet. 2016 Mar; 12(3):e1005738. Booker BM, Friedrich T, Mason MK, VanderMeer JE, Zhao J, Eckalbar WL, Logan M, Illing N, Pollard KS, Ahituv N. PMID: 27019019.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    38. Transcriptomic and epigenomic characterization of the developing bat wing. Nat Genet. 2016 05; 48(5):528-36. Eckalbar WL, Schlebusch SA, Mason MK, Gill Z, Parker AV, Booker BM, Nishizaki S, Muswamba-Nday C, Terhune E, Nevonen KA, Makki N, Friedrich T, VanderMeer JE, Pollard KS, Carbone L, Wall JD, Illing N, Ahituv N. PMID: 27019111.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    39. Exonic enhancers: proceed with caution in exome and genome sequencing studies. Genome Med. 2016 Feb 08; 8(1):14. Ahituv N. PMID: 26856702.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    40. Prenatal ß-catenin/Brn2/Tbr2 transcriptional cascade regulates adult social and stereotypic behaviors. Mol Psychiatry. 2016 10; 21(10):1417-33. Belinson H, Nakatani J, Babineau BA, Birnbaum RY, Ellegood J, Bershteyn M, McEvilly RJ, Long JM, Willert K, Klein OD, Ahituv N, Lerch JP, Rosenfeld MG, Wynshaw-Boris A. PMID: 26830142.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    41. A genome-wide association study identifies four novel susceptibility loci underlying inguinal hernia. Nat Commun. 2015 Dec 21; 6:10130. Jorgenson E, Makki N, Shen L, Chen DC, Tian C, Eckalbar WL, Hinds D, Ahituv N, Avins A. PMID: 26686553.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimals
    42. Minor Loops in Major Folds: Enhancer-Promoter Looping, Chromatin Restructuring, and Their Association with Transcriptional Regulation and Disease. PLoS Genet. 2015 Dec; 11(12):e1005640. Matharu N, Ahituv N. PMID: 26632825.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    43. The human ARF tumor suppressor senses blastema activity and suppresses epimorphic tissue regeneration. Elife. 2015 Nov 17; 4. Hesse RG, Kouklis GK, Ahituv N, Pomerantz JH. PMID: 26575287.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    44. Uncovering drug-responsive regulatory elements. Pharmacogenomics. 2015 Nov; 16(16):1829-41. Luizon MR, Ahituv N. PMID: 26555224.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    45. Functionally conserved enhancers with divergent sequences in distant vertebrates. BMC Genomics. 2015 Oct 30; 16:882. Yang S, Oksenberg N, Takayama S, Heo SJ, Poliakov A, Ahituv N, Dubchak I, Boffelli D. PMID: 26519295.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    46. Identification of novel Fgf enhancers and their role in dental evolution. Evol Dev. 2016 Jan-Feb; 18(1):31-40. Tapaltsyan V, Charles C, Hu J, Mindell D, Ahituv N, Wilson GM, Black BL, Viriot L, Klein OD. PMID: 26086993.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    47. Decoding enhancers using massively parallel reporter assays. Genomics. 2015 Sep; 106(3):159-164. Inoue F, Ahituv N. PMID: 26072433.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    48. A PAX1 enhancer locus is associated with susceptibility to idiopathic scoliosis in females. Nat Commun. 2015 Mar 18; 6:6452. Sharma S, Londono D, Eckalbar WL, Gao X, Zhang D, Mauldin K, Kou I, Takahashi A, Matsumoto M, Kamiya N, Murphy KK, Cornelia R, Herring JA, Burns D, Ahituv N, Ikegawa S, Gordon D, Wise CA. PMID: 25784220.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    49. Systematic dissection of coding exons at single nucleotide resolution supports an additional role in cell-specific transcriptional regulation. PLoS Genet. 2014 Oct; 10(10):e1004592. Birnbaum RY, Patwardhan RP, Kim MJ, Findlay GM, Martin B, Zhao J, Bell RJ, Smith RP, Ku AA, Shendure J, Ahituv N. PMID: 25340400.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    50. Enhancer interaction networks as a means for singular olfactory receptor expression. Cell. 2014 Oct 23; 159(3):543-57. Markenscoff-Papadimitriou E, Allen WE, Colquitt BM, Goh T, Murphy KK, Monahan K, Mosley CP, Ahituv N, Lomvardas S. PMID: 25417106.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    51. Genome-wide discovery of drug-dependent human liver regulatory elements. PLoS Genet. 2014 Oct; 10(10):e1004648. Smith RP, Eckalbar WL, Morrissey KM, Luizon MR, Hoffmann TJ, Sun X, Jones SL, Force Aldred S, Ramamoorthy A, Desta Z, Liu Y, Skaar TC, Trinklein ND, Giacomini KM, Ahituv N. PMID: 25275310.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    52. Genome-wide identification of signaling center enhancers in the developing limb. Development. 2014 Nov; 141(21):4194-8. VanderMeer JE, Smith RP, Jones SL, Ahituv N. PMID: 25273087.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    53. Genome-wide distribution of Auts2 binding localizes with active neurodevelopmental genes. Transl Psychiatry. 2014 Sep 02; 4:e431. Oksenberg N, Haliburton GD, Eckalbar WL, Oren I, Nishizaki S, Murphy K, Pollard KS, Birnbaum RY, Ahituv N. PMID: 25180570.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    54. Integrating diverse datasets improves developmental enhancer prediction. PLoS Comput Biol. 2014 Jun; 10(6):e1003677. Erwin GD, Oksenberg N, Truty RM, Kostka D, Murphy KK, Ahituv N, Pollard KS, Capra JA. PMID: 24967590.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    55. A novel ZRS mutation leads to preaxial polydactyly type 2 in a heterozygous form and Werner mesomelic syndrome in a homozygous form. Hum Mutat. 2014 Aug; 35(8):945-8. VanderMeer JE, Lozano R, Sun M, Xue Y, Daentl D, Jabs EW, Wilcox WR, Ahituv N. PMID: 24777739.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    56. Identification of three novel FGF16 mutations in X-linked recessive fusion of the fourth and fifth metacarpals and possible correlation with heart disease. Mol Genet Genomic Med. 2014 Sep; 2(5):402-11. Laurell T, Nilsson D, Hofmeister W, Lindstrand A, Ahituv N, Vandermeer J, Amilon A, Annerén G, Arner M, Pettersson M, Jäntti N, Rosberg HE, Cattini PA, Nordenskjöld A, Mäkitie O, Grigelioniene G, Nordgren A. PMID: 25333065.
      View in: PubMed   Mentions: 5     Fields:    
    57. Genetic association study of adiposity and melanocortin-4 receptor (MC4R) common variants: replication and functional characterization of non-coding regions. PLoS One. 2014; 9(5):e96805. Evans DS, Calton MA, Kim MJ, Kwok PY, Miljkovic I, Harris T, Koster A, Liu Y, Tranah GJ, Ahituv N, Hsueh WC, Vaisse C. PMID: 24820477.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
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