Nadav Ahituv, PhD

Title(s)Professor, Bioengineering
SchoolSchool of Pharmacy
Address1550 Fourth Street, #584C
San Francisco CA 94158
Phone415-476-1838
ORCID ORCID Icon0000-0002-7434-8144 Additional info
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    Collapse Biography 
    Collapse Awards and Honors
    Tel-Aviv University2002  - 2002Ph.D. with distinction
    The American Society for Clinical Pharmacology and Therapeutics2014  - 2014ASCPT Leon I. Goldberg young investigator award

    Collapse Overview 
    Collapse Overview
    The Ahituv lab is focused on identifying gene regulatory elements and linking nucleotide variation within them to various phenotypes including morphological differences between species, drug response and human disease. In addition, our lab is developing massively parallel reporter assays (MPRAs) that allow for high-throughput functional characterization of gene regulatory elements and the use of gene regulatory elements as therapeutic targets or disease diagnostic markers.

    Collapse Research 
    Collapse Research Activities and Funding
    Massively parallel characterization of variants and elements impacting transcriptional regulation in dynamic cellular systems
    NIH UM1HG011966Sep 1, 2021 - May 31, 2026
    Role: Co-Principal Investigator
    From Obesity GWAS to therapeutic targets
    NIH R01DK124769Jul 1, 2020 - Jun 30, 2025
    Role: Co-Principal Investigator
    Technologies for simultaneous characterization of regulatory activity and protein binding
    NIH R21HG010683Aug 16, 2019 - Jul 31, 2021
    Role: Principal Investigator
    Genetic Etiology of Abdominal Hernia Susceptibility
    NIH R01DK116738Sep 15, 2018 - Aug 31, 2021
    Role: Co-Principal Investigator
    Massively parallel characterization of psychiatric disease associated regulatory elements in defined cell types
    NIH U01MH116438Jul 6, 2018 - Mar 31, 2023
    Role: Principal Investigator
    Development of massively parallel reporter assays that use cognate promoters
    NIH R21HG010065May 1, 2018 - Apr 30, 2020
    Role: Co-Principal Investigator
    Massively parallel reporter assays and genome editing of ENCODE predicted regulatory elements
    NIH UM1HG009408Feb 1, 2017 - Jan 31, 2022
    Role: Principal Investigator
    Developmental Mechanisms of Human Idiopathic Scoliosis
    NIH P01HD084387Sep 1, 2016 - Jun 30, 2021
    Role: Co-Principal Investigator
    Massively parallel dissection of psychiatric regulatory networks
    NIH R01MH109907May 1, 2016 - Feb 28, 2021
    Role: Co-Principal Investigator
    The Airway Functional Genomics of Bronchodilator Drug Response in Minority Children with Asthma
    NIH R01HL117004Aug 1, 2013 - Jun 30, 2023
    Role: Co-Principal Investigator
    Identification & functional characterization of SIM1 obesity-associated variants
    NIH R01DK090382May 1, 2012 - Mar 31, 2016
    Role: Co-Principal Investigator
    Massively parallel, in vivo functional testing of regulatory elements
    NIH R01HG006768Apr 24, 2012 - Jun 30, 2015
    Role: Co-Principal Investigator
    Characterization of neuronal gene regulatory elements associated with epilepsy
    NIH R01NS079231Apr 1, 2012 - Mar 31, 2016
    Role: Principal Investigator
    Computational & Functional Annotation of the Zebrafish Genome Regulatory Toolbox
    NIH R01HG005058Sep 29, 2009 - Jul 31, 2014
    Role: Co-Principal Investigator
    Characterization of regulatory elements leading to human limb malformations
    NIH R01HD059862Apr 1, 2009 - Mar 31, 2015
    Role: Principal Investigator
    Pharmacogenomics of Membrane Transporters
    NIH U19GM061390Apr 1, 2000 - Jun 30, 2015
    Role: Co-Investigator
    Pharmaceutical Sciences and Pharmacogenomics
    NIH T32GM007175Jul 1, 1982 - Jun 30, 2022
    Role: Co-Principal Investigator

    Collapse ORNG Applications 
    Collapse Academic Senate

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Multiplex, single-cell CRISPRa screening for cell type specific regulatory elements. Nat Commun. 2024 Sep 18; 15(1):8209. Chardon FM, McDiarmid TA, Page NF, Daza RM, Martin BK, Domcke S, Regalado SG, Lalanne JB, Calderon D, Li X, Starita LM, Sanders SJ, Ahituv N, Shendure J. PMID: 39294132; PMCID: PMC11411074.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    2. Comprehensive network modeling approaches unravel dynamic enhancer-promoter interactions across neural differentiation. Genome Biol. 2024 Aug 14; 25(1):221. DeGroat W, Inoue F, Ashuach T, Yosef N, Ahituv N, Kreimer A. PMID: 39143563; PMCID: PMC11323586.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    3. Deletion of an evolutionarily conserved TAD boundary compromises spermatogenesis in mice. bioRxiv. 2024 Jul 10. Lima AC, Okhovat M, Stendahl AM, VanCampen J, Nevonen KA, Herrera J, Li W, Harshman L, Yang R, Fedorov LM, Vigh-Conrad KA, Ahituv N, Conrad DF, Carbone L. PMID: 39026739; PMCID: PMC11257473.
      View in: PubMed   Mentions:
    4. Genetic regulation of cell type-specific chromatin accessibility shapes brain disease etiology. Science. 2024 May 24; 384(6698):eadh4265. Zeng B, Bendl J, Deng C, Lee D, Misir R, Reach SM, Kleopoulos SP, Auluck P, Marenco S, Lewis DA, Haroutunian V, Ahituv N, Fullard JF, Hoffman GE, Roussos P. PMID: 38781378.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    5. Massively parallel characterization of regulatory elements in the developing human cortex. Science. 2024 May 24; 384(6698):eadh0559. Deng C, Whalen S, Steyert M, Ziffra R, Przytycki PF, Inoue F, Pereira DA, Capauto D, Norton S, Vaccarino FM, PsychENCODE Consortium‡, Pollen AA, Nowakowski TJ, Ahituv N, Pollard KS, PsychENCODE Consortium. PMID: 38781390.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    6. Comprehensive network modeling approaches unravel dynamic enhancer-promoter interactions across neural differentiation. bioRxiv. 2024 May 23. DeGroat W, Inoue F, Ashuach T, Yosef N, Ahituv N, Kreimer A. PMID: 38826254; PMCID: PMC11142193.
      View in: PubMed   Mentions:
    7. Multiplex, single-cell CRISPRa screening for cell type specific regulatory elements. bioRxiv. 2024 Apr 30. Chardon FM, McDiarmid TA, Page NF, Daza RM, Martin B, Domcke S, Regalado SG, Lalanne JB, Calderon D, Li X, Starita LM, Sanders SJ, Ahituv N, Shendure J. PMID: 37034704; PMCID: PMC10081248.
      View in: PubMed   Mentions:
    8. Massively parallel reporter assays and mouse transgenic assays provide complementary information about neuronal enhancer activity. bioRxiv. 2024 Apr 23. Kosicki M, Cintrón DL, Page NF, Georgakopoulos-Soares I, Akiyama JA, Plajzer-Frick I, Novak CS, Kato M, Hunter RD, von Maydell K, Barton S, Godfrey P, Beckman E, Sanders SJ, Pennacchio LA, Ahituv N. PMID: 38712228; PMCID: PMC11071441.
      View in: PubMed   Mentions:
    9. Massively parallel jumping assay decodes Alu retrotransposition activity. bioRxiv. 2024 Apr 19. Matharu N, Zhao J, Sohota A, Deng L, Hung Y, Li Z, Sims J, Rattanasopha S, Meyer J, Carbone L, Kircher M, Ahituv N. PMID: 38659854; PMCID: PMC11042287.
      View in: PubMed   Mentions:
    10. Deletion of Pax1 scoliosis-associated regulatory elements leads to a female-biased tail abnormality. Cell Rep. 2024 Mar 26; 43(3):113907. Ushiki A, Sheng RR, Zhang Y, Zhao J, Nobuhara M, Murray E, Ruan X, Rios JJ, Wise CA, Ahituv N. PMID: 38461417; PMCID: PMC11005513.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    11. Author Correction: Genomic and epigenomic mapping of leptin-responsive neuronal populations involved in body weight regulation. Nat Metab. 2024 Mar; 6(3):598. Inoue F, Eckalbar WL, Wang Y, Murphy KK, Matharu N, Vaisse C, Ahituv N. PMID: 38429391.
      View in: PubMed   Mentions:    Fields:    
    12. Optimizing sequence design strategies for perturbation MPRAs: a computational evaluation framework. Nucleic Acids Res. 2024 Feb 28; 52(4):1613-1627. Liu J, Ashuach T, Inoue F, Ahituv N, Yosef N, Kreimer A. PMID: 38296821; PMCID: PMC10939410.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    13. Author Correction: Integrative single-cell characterization of a frugivorous and an insectivorous bat kidney and pancreas. Nat Commun. 2024 Feb 27; 15(1):1777. Gordon WE, Baek S, Nguyen HP, Kuo YM, Bradley R, Fong SL, Kim N, Galazyuk A, Lee I, Ingala MR, Simmons NB, Schountz T, Cooper LN, Georgakopoulos-Soares I, Hemberg M, Ahituv N. PMID: 38413559; PMCID: PMC10899600.
      View in: PubMed   Mentions:    Fields:    
    14. Impaired cerebellar plasticity hypersensitizes sensory reflexes in SCN2A-associated ASD. Neuron. 2024 May 01; 112(9):1444-1455.e5. Wang C, Derderian KD, Hamada E, Zhou X, Nelson AD, Kyoung H, Ahituv N, Bouvier G, Bender KJ. PMID: 38412857; PMCID: PMC11065582.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    15. Characterization of enhancer activity in early human neurodevelopment using Massively Parallel Reporter Assay (MPRA) and forebrain organoids. Sci Rep. 2024 02 16; 14(1):3936. Capauto D, Wang Y, Wu F, Norton S, Mariani J, Inoue F, Crawford GE, Ahituv N, Abyzov A, Vaccarino FM. PMID: 38365907; PMCID: PMC10873509.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    16. Association of genetic variation in COL11A1 with adolescent idiopathic scoliosis. Elife. 2024 Jan 26; 12. Yu H, Khanshour AM, Ushiki A, Otomo N, Koike Y, Einarsdottir E, Fan Y, Antunes L, Kidane YH, Cornelia R, Sheng RR, Zhang Y, Pei J, Grishin NV, Evers BM, Cheung JPY, Herring JA, Terao C, Song YQ, Gurnett CA, Gerdhem P, Ikegawa S, Rios JJ, Ahituv N, Wise CA. PMID: 38277211; PMCID: PMC10945706.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    17. Association of genetic variation in COL11A1 with adolescent idiopathic scoliosis. eLife. 2024 Jan 26; 12. Yu YH, Khanshour KA, Ushiki UA, Otomo ON, Koike KY, Einarsdottir EE, Fan FY, Antunes AL, Kidane KY, Cornelia CR, Sheng SR, Zhang ZY, Pei PJ, Grishin GN, Evers EB, Cheung CJ, Herring HJ, Terao TC, Song SY, Gurnett GC, Gerdhem GP, Ikegawa IS, Rios RJ, Ahituv AN, Wise WC. .
      View in: Publisher Site   Mentions:
    18. Integrative functional genomic analyses identify genetic variants influencing skin pigmentation in Africans. Nat Genet. 2024 Feb; 56(2):258-272. Feng Y, Xie N, Inoue F, Fan S, Saskin J, Zhang C, Zhang F, Hansen MEB, Nyambo T, Mpoloka SW, Mokone GG, Fokunang C, Belay G, Njamnshi AK, Marks MS, Oancea E, Ahituv N, Tishkoff SA. PMID: 38200130; PMCID: PMC11005318.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    19. Integrative single-cell characterization of a frugivorous and an insectivorous bat kidney and pancreas. Nat Commun. 2024 01 09; 15(1):12. Gordon WE, Baek S, Nguyen HP, Kuo YM, Bradley R, Fong SL, Kim N, Galazyuk A, Lee I, Ingala MR, Simmons NB, Schountz T, Cooper LN, Georgakopoulos-Soares I, Hemberg M, Ahituv N. PMID: 38195585; PMCID: PMC10776631.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    20. TAD evolutionary and functional characterization reveals diversity in mammalian TAD boundary properties and function. Nat Commun. 2023 Dec 07; 14(1):8111. Okhovat M, VanCampen J, Nevonen KA, Harshman L, Li W, Layman CE, Ward S, Herrera J, Wells J, Sheng RR, Mao Y, Ndjamen B, Lima AC, Vigh-Conrad KA, Stendahl AM, Yang R, Fedorov L, Matthews IR, Easow SA, Chan DK, Jan TA, Eichler EE, Rugonyi S, Conrad DF, Ahituv N, Carbone L. PMID: 38062027; PMCID: PMC10703881.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    21. Author Correction: Chromatin compartmentalization regulates the response to DNA damage. Nature. 2023 Dec; 624(7990):E1. Arnould C, Rocher V, Saur F, Bader AS, Muzzopappa F, Collins S, Lesage E, Le Bozec B, Puget N, Clouaire T, Mangeat T, Mourad R, Ahituv N, Noordermeer D, Erdel F, Bushell M, Marnef A, Legube G. PMID: 37974007; PMCID: PMC10700127.
      View in: PubMed   Mentions:    Fields:    
    22. MPRAbase: A Massively Parallel Reporter Assay Database. bioRxiv. 2023 Nov 22. Zhao J, Baltoumas FA, Konnaris MA, Mouratidis I, Liu Z, Sims J, Agarwal V, Pavlopoulos GA, Georgakopoulos-Soares I, Ahituv N. PMID: 38045264; PMCID: PMC10690217.
      View in: PubMed   Mentions:
    23. Association of genetic variation in COL11A1 with adolescent idiopathic scoliosis. bioRxiv. 2023 Nov 22. Yu H, Khanshour AM, Ushiki A, Otomo N, Koike Y, Einarsdottir E, Fan Y, Antunes L, Kidane YH, Cornelia R, Sheng R, Zhang Y, Pei J, Grishin NV, Evers BM, Cheung JPY, Herring JA, Terao C, Song YQ, Gurnett CA, Gerdhem P, Ikegawa S, Rios JJ, Ahituv N, Wise CA. PMID: 37292598; PMCID: PMC10245954.
      View in: PubMed   Mentions:
    24. Chromatin compartmentalization regulates the response to DNA damage. Nature. 2023 Nov; 623(7985):183-192. Arnould C, Rocher V, Saur F, Bader AS, Muzzopappa F, Collins S, Lesage E, Le Bozec B, Puget N, Clouaire T, Mangeat T, Mourad R, Ahituv N, Noordermeer D, Erdel F, Bushell M, Marnef A, Legube G. PMID: 37853125; PMCID: PMC10620078.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    25. Best practices for perturbation MPRA-a computational evaluation framework of sequence design strategies. bioRxiv. 2023 Sep 29. Liu J, Ashuach T, Inoue F, Ahituv N, Yosef N, Kreimer A. PMID: 37808807; PMCID: PMC10557651.
      View in: PubMed   Mentions:
    26. Milk antibody response after 3rd COVID-19 vaccine and SARS-CoV-2 infection and implications for infant protection. iScience. 2023 Oct 20; 26(10):107767. Golan Y, Ilala M, Li L, Gay C, Hunagund S, Lin CY, Cassidy AG, Jigmeddagva U, Matsui Y, Ozarslan N, Asiodu IV, Ahituv N, Flaherman VJ, Gaw SL, Prahl M. PMID: 37731614; PMCID: PMC10507209.
      View in: PubMed   Mentions: 6  
    27. Characterization of enhancer activity in early human neurodevelopment using Massively parallel reporter assay (MPRA) and forebrain organoids. bioRxiv. 2023 Aug 14. Capauto D, Wang Y, Wu F, Norton S, Mariani J, Inoue F, Crawford GE, PsychENCODE Consortium, Ahituv N, Abyzov A, Vaccarino FM. PMID: 37645832; PMCID: PMC10461976.
      View in: PubMed   Mentions:
    28. Impaired cerebellar plasticity hypersensitizes sensory reflexes in SCN2A-associated ASD. bioRxiv. 2023 Jun 07. Wang C, Derderian KD, Hamada E, Zhou X, Nelson AD, Kyoung H, Ahituv N, Bouvier G, Bender KJ. PMID: 37333267; PMCID: PMC10274749.
      View in: PubMed   Mentions:
    29. Three-dimensional genome rewiring in loci with human accelerated regions. Science. 2023 04 28; 380(6643):eabm1696. Keough KC, Whalen S, Inoue F, Przytycki PF, Fair T, Deng C, Steyert M, Ryu H, Lindblad-Toh K, Karlsson E, Zoonomia Consortium§, Nowakowski T, Ahituv N, Pollen A, Pollard KS. PMID: 37104607; PMCID: PMC10999243.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    30. Quasi-prime peptides: identification of the shortest peptide sequences unique to a species. NAR Genom Bioinform. 2023 Jun; 5(2):lqad039. Mouratidis I, Chan CSY, Chantzi N, Tsiatsianis GC, Hemberg M, Ahituv N, Georgakopoulos-Soares I. PMID: 37101657; PMCID: PMC10124967.
      View in: PubMed   Mentions: 7  
    31. Transcription factor binding site orientation and order are major drivers of gene regulatory activity. Nat Commun. 2023 04 22; 14(1):2333. Georgakopoulos-Soares I, Deng C, Agarwal V, Chan CSY, Zhao J, Inoue F, Ahituv N. PMID: 37087538; PMCID: PMC10122648.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    32. Deletion of Pax1 scoliosis-associated regulatory elements leads to a female-biased tail abnormality. bioRxiv. 2023 Apr 13. Ushiki A, Sheng RR, Zhang Y, Zhao J, Nobuhara M, Murray E, Ruan X, Rios JJ, Wise CA, Ahituv N. PMID: 37090618; PMCID: PMC10120660.
      View in: PubMed   Mentions:
    33. Abstract 991: Leveraging sequences missing from the human genome to detect cancer. Cancer Research. 2023 Apr 4; 83(7_Supplement):991-991. Barnea BO, Georgakopoulos-Soares GI, Ahituv AN, Chapman CJ, Hemberg HM, Mouratidis MI, Syrigos SK, Syrigos SN, Vathiotis VI, Mahajan MM, Panagiotou PE, Charpidou CA, Kvale KM, Chan CC, Easterlin ER. .
      View in: Publisher Site   Mentions:
    34. Implantation of engineered adipocytes that outcompete tumors for resources suppresses cancer progression. bioRxiv. 2023 Mar 29. Nguyen HP, Sheng R, Murray E, Ito Y, Bruck M, Biellak C, An K, Lynce F, Dillon DA, Magbanua MJM, Huppert LA, Hammerlindl H, Esserman L, Rosenbluth JM, Ahituv N. PMID: 37034710; PMCID: PMC10081280.
      View in: PubMed   Mentions:
    35. TAD Evolutionary and functional characterization reveals diversity in mammalian TAD boundary properties and function. bioRxiv. 2023 Mar 07. Okhovat M, VanCampen J, Lima AC, Nevonen KA, Layman CE, Ward S, Herrera J, Stendahl AM, Yang R, Harshman L, Li W, Sheng RR, Mao Y, Fedorov L, Ndjamen B, Vigh-Conrad KA, Matthews IR, Easow SA, Chan DK, Jan TA, Eichler EE, Rugonyi S, Conrad DF, Ahituv N, Carbone L. PMID: 36945527; PMCID: PMC10028908.
      View in: PubMed   Mentions:
    36. Massively parallel characterization of transcriptional regulatory elements in three diverse human cell types. bioRxiv. 2023 Mar 06. Agarwal V, Inoue F, Schubach M, Martin BK, Dash PM, Zhang Z, Sohota A, Noble WS, Yardimci GG, Kircher M, Shendure J, Ahituv N. PMID: 36945371; PMCID: PMC10028905.
      View in: PubMed   Mentions:
    37. Genetic regulation of cell-type specific chromatin accessibility shapes the etiology of brain diseases. bioRxiv. 2023 Mar 02. Zeng B, Bendl J, Deng C, Lee D, Misir R, Reach SM, Kleopoulos SP, Auluck P, Marenco S, Lewis DA, Haroutunian V, Ahituv N, Fullard JF, Hoffman GE, Roussos P. PMID: 37090548; PMCID: PMC10120699.
      View in: PubMed   Mentions:
    38. Massively parallel characterization of psychiatric disorder-associated and cell-type-specific regulatory elements in the developing human cortex. bioRxiv. 2023 Feb 16. Deng C, Whalen S, Steyert M, Ziffra R, Przytycki PF, Inoue F, Pereira DA, Capauto D, Norton S, Vaccarino FM, Pollen A, Nowakowski TJ, Ahituv N, Pollard KS. PMID: 36824845; PMCID: PMC9949039.
      View in: PubMed   Mentions:
    39. Integrative single-cell characterization of frugivory adaptations in the bat kidney and pancreas. bioRxiv. 2023 Feb 13. Gordon WE, Baek S, Nguyen HP, Kuo YM, Bradley R, Galazyuk A, Lee I, Ingala MR, Simmons NB, Schountz T, Cooper LN, Georgakopoulos-Soares I, Hemberg M, Ahituv N. PMID: 36824791; PMCID: PMC9949079.
      View in: PubMed   Mentions:
    40. Characterization of De Novo Promoter Variants in Autism Spectrum Disorder with Massively Parallel Reporter Assays. Int J Mol Sci. 2023 Feb 09; 24(4). Koesterich J, An JY, Inoue F, Sohota A, Ahituv N, Sanders SJ, Kreimer A. PMID: 36834916; PMCID: PMC9959321.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    41. Risk scoring based on DNA methylation-driven related DEGs for colorectal cancer prognosis with systematic insights. Life Sci. 2023 Mar 01; 316:121413. Liu Z, Georgakopoulos-Soares I, Ahituv N, Wong KC. PMID: 36682524.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    42. Machine learning dissection of human accelerated regions in primate neurodevelopment. Neuron. 2023 03 15; 111(6):857-873.e8. Whalen S, Inoue F, Ryu H, Fair T, Markenscoff-Papadimitriou E, Keough K, Kircher M, Martin B, Alvarado B, Elor O, Laboy Cintron D, Williams A, Hassan Samee MA, Thomas S, Krencik R, Ullian EM, Kriegstein A, Rubenstein JL, Shendure J, Pollen AA, Ahituv N, Pollard KS. PMID: 36640767; PMCID: PMC10023452.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    43. Milk antibody response after 3rd dose of COVID-19 mRNA vaccine and SARS-CoV-2 breakthrough infection and implications for infant protection. medRxiv. 2022 Dec 14. Golan Y, Ilala M, Gay C, Hunagund S, Lin CY, Cassidy AG, Jigmeddagva U, Li L, Ozarslan N, Asiodu IV, Ahituv N, Flaherman VJ, Gaw SL, Prahl M. PMID: 36561188; PMCID: PMC9774223.
      View in: PubMed   Mentions:
    44. Genomic characterization and therapeutic utilization of IL-13-responsive sequences in asthma. Cell Genom. 2023 Jan 11; 3(1):100229. Koh KD, Bonser LR, Eckalbar WL, Yizhar-Barnea O, Shen J, Zeng X, Hargett KL, Sun DI, Zlock LT, Finkbeiner WE, Ahituv N, Erle DJ. PMID: 36777184; PMCID: PMC9903679.
      View in: PubMed   Mentions: 6     Fields:    
    45. Author Correction: High-throughput techniques enable advances in the roles of DNA and RNA secondary structures in transcriptional and post-transcriptional gene regulation. Genome Biol. 2022 Jul 27; 23(1):164. Georgakopoulos-Soares I, Chan CSY, Ahituv N, Hemberg M. PMID: 35897074; PMCID: PMC9327390.
      View in: PubMed   Mentions:    Fields:    
    46. High-throughput techniques enable advances in the roles of DNA and RNA secondary structures in transcriptional and post-transcriptional gene regulation. Genome Biol. 2022 07 18; 23(1):159. Georgakopoulos-Soares I, Chan CSY, Ahituv N, Hemberg M. PMID: 35851062; PMCID: PMC9290270.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    47. Ancestry- and sex-specific effects underlying inguinal hernia susceptibility identified in a multiethnic genome-wide association study meta-analysis. Hum Mol Genet. 2022 07 07; 31(13):2279-2293. Choquet H, Li W, Yin J, Bradley R, Hoffmann TJ, Nandakumar P, 23 and Me Research Team, Mostaedi R, Tian C, Ahituv N, Jorgenson E. PMID: 35022708; PMCID: PMC9262393.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    48. Cellular and transcriptional diversity over the course of human lactation. Proc Natl Acad Sci U S A. 2022 04 12; 119(15):e2121720119. Nyquist SK, Gao P, Haining TKJ, Retchin MR, Golan Y, Drake RS, Kolb K, Mead BE, Ahituv N, Martinez ME, Shalek AK, Berger B, Goods BA. PMID: 35377806; PMCID: PMC9169737.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    49. Massively parallel reporter perturbation assays uncover temporal regulatory architecture during neural differentiation. Nat Commun. 2022 03 21; 13(1):1504. Kreimer A, Ashuach T, Inoue F, Khodaverdian A, Deng C, Yosef N, Ahituv N. PMID: 35315433; PMCID: PMC8938438.
      View in: PubMed   Mentions: 21     Fields:    Translation:Cells
    50. High-throughput characterization of the role of non-B DNA motifs on promoter function. Cell Genom. 2022 Apr 13; 2(4). Georgakopoulos-Soares I, Victorino J, Parada GE, Agarwal V, Zhao J, Wong HY, Umar MI, Elor O, Muhwezi A, An JY, Sanders SJ, Kwok CK, Inoue F, Hemberg M, Ahituv N. PMID: 35573091; PMCID: PMC9105345.
      View in: PubMed   Mentions: 17     Fields:    
    51. COVID-19 mRNA Vaccination in Lactation: Assessment of Adverse Events and Vaccine Related Antibodies in Mother-Infant Dyads. Front Immunol. 2021; 12:777103. Golan Y, Prahl M, Cassidy AG, Gay C, Wu AHB, Jigmeddagva U, Lin CY, Gonzalez VJ, Basilio E, Chidboy MA, Warrier L, Buarpung S, Li L, Murtha AP, Asiodu IV, Ahituv N, Flaherman VJ, Gaw SL. PMID: 34804068; PMCID: PMC8595828.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCellsCTClinical Trials
    52. Oestrogen engages brain MC4R signalling to drive physical activity in female mice. Nature. 2021 11; 599(7883):131-135. Krause WC, Rodriguez R, Gegenhuber B, Matharu N, Rodriguez AN, Padilla-Roger AM, Toma K, Herber CB, Correa SM, Duan X, Ahituv N, Tollkuhn J, Ingraham HA. PMID: 34646010; PMCID: PMC9113400.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
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    118. Genome-wide discovery of drug-dependent human liver regulatory elements. PLoS Genet. 2014 Oct; 10(10):e1004648. Smith RP, Eckalbar WL, Morrissey KM, Luizon MR, Hoffmann TJ, Sun X, Jones SL, Force Aldred S, Ramamoorthy A, Desta Z, Liu Y, Skaar TC, Trinklein ND, Giacomini KM, Ahituv N. PMID: 25275310; PMCID: PMC4183418.
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    120. Genome-wide distribution of Auts2 binding localizes with active neurodevelopmental genes. Transl Psychiatry. 2014 Sep 02; 4:e431. Oksenberg N, Haliburton GD, Eckalbar WL, Oren I, Nishizaki S, Murphy K, Pollard KS, Birnbaum RY, Ahituv N. PMID: 25180570; PMCID: PMC4199417.
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    122. A novel ZRS mutation leads to preaxial polydactyly type 2 in a heterozygous form and Werner mesomelic syndrome in a homozygous form. Hum Mutat. 2014 Aug; 35(8):945-8. VanderMeer JE, Lozano R, Sun M, Xue Y, Daentl D, Jabs EW, Wilcox WR, Ahituv N. PMID: 24777739; PMCID: PMC4110103.
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    123. Identification of three novel FGF16 mutations in X-linked recessive fusion of the fourth and fifth metacarpals and possible correlation with heart disease. Mol Genet Genomic Med. 2014 Sep; 2(5):402-11. Laurell T, Nilsson D, Hofmeister W, Lindstrand A, Ahituv N, Vandermeer J, Amilon A, Annerén G, Arner M, Pettersson M, Jäntti N, Rosberg HE, Cattini PA, Nordenskjöld A, Mäkitie O, Grigelioniene G, Nordgren A. PMID: 25333065; PMCID: PMC4190875.
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    128. Classification of topological domains based on gene expression and regulation. Genome. 2013 Jul; 56(7):415-23. Zhao J, Shi H, Ahituv N. PMID: 24099394; PMCID: PMC3873163.
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    129. The role of AUTS2 in neurodevelopment and human evolution. Trends Genet. 2013 Oct; 29(10):600-8. Oksenberg N, Ahituv N. PMID: 24008202; PMCID: PMC3823538.
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    135. Mutations in DMRT3 affect locomotion in horses and spinal circuit function in mice. Nature. 2012 Aug 30; 488(7413):642-6. Andersson LS, Larhammar M, Memic F, Wootz H, Schwochow D, Rubin CJ, Patra K, Arnason T, Wellbring L, Hjälm G, Imsland F, Petersen JL, McCue ME, Mickelson JR, Cothran G, Ahituv N, Roepstorff L, Mikko S, Vallstedt A, Lindgren G, Andersson L, Kullander K. PMID: 22932389; PMCID: PMC3523687.
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    136. Functional characterization of tissue-specific enhancers in the DLX5/6 locus. Hum Mol Genet. 2012 Nov 15; 21(22):4930-8. Birnbaum RY, Everman DB, Murphy KK, Gurrieri F, Schwartz CE, Ahituv N. PMID: 22914741; PMCID: PMC3529576.
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    138. A novel ZRS mutation in a Balochi tribal family with triphalangeal thumb, pre-axial polydactyly, post-axial polydactyly, and syndactyly. Am J Med Genet A. 2012 Aug; 158A(8):2031-5. VanderMeer JE, Afzal M, Alyas S, Haque S, Ahituv N, Malik S. PMID: 22786669; PMCID: PMC3402602.
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    142. Coding exons function as tissue-specific enhancers of nearby genes. Genome Res. 2012 Jun; 22(6):1059-68. Birnbaum RY, Clowney EJ, Agamy O, Kim MJ, Zhao J, Yamanaka T, Pappalardo Z, Clarke SL, Wenger AM, Nguyen L, Gurrieri F, Everman DB, Schwartz CE, Birk OS, Bejerano G, Lomvardas S, Ahituv N. PMID: 22442009; PMCID: PMC3371700.
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    150. Identification and characterization of novel polymorphisms in the basal promoter of the human transporter, MATE1. Pharmacogenet Genomics. 2009 Oct; 19(10):770-80. Ha Choi J, Wah Yee S, Kim MJ, Nguyen L, Ho Lee J, Kang JO, Hesselson S, Castro RA, Stryke D, Johns SJ, Kwok PY, Ferrin TE, Goo Lee M, Black BL, Ahituv N, Giacomini KM. PMID: 19745787; PMCID: PMC2976711.
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    151. Identification and characterization of proximal promoter polymorphisms in the human concentrative nucleoside transporter 2 (SLC28A2). J Pharmacol Exp Ther. 2009 Mar; 328(3):699-707. Yee SW, Shima JE, Hesselson S, Nguyen L, De Val S, Lafond RJ, Kawamoto M, Johns SJ, Stryke D, Kwok PY, Ferrin TE, Black BL, Gurwitz D, Ahituv N, Giacomini KM. PMID: 19098160; PMCID: PMC2682268.
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    152. Association of functionally significant Melanocortin-4 but not Melanocortin-3 receptor mutations with severe adult obesity in a large North American case-control study. Hum Mol Genet. 2009 Mar 15; 18(6):1140-7. Calton MA, Ersoy BA, Zhang S, Kane JP, Malloy MJ, Pullinger CR, Bromberg Y, Pennacchio LA, Dent R, McPherson R, Ahituv N, Vaisse C. PMID: 19091795; PMCID: PMC2649015.
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    157. Gain-of-function R225W mutation in human AMPKgamma(3) causing increased glycogen and decreased triglyceride in skeletal muscle. PLoS One. 2007 Sep 19; 2(9):e903. Costford SR, Kavaslar N, Ahituv N, Chaudhry SN, Schackwitz WS, Dent R, Pennacchio LA, McPherson R, Harper ME. PMID: 17878938; PMCID: PMC1964808.
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    160. In vivo enhancer analysis of human conserved non-coding sequences. Nature. 2006 Nov 23; 444(7118):499-502. Pennacchio LA, Ahituv N, Moses AM, Prabhakar S, Nobrega MA, Shoukry M, Minovitsky S, Dubchak I, Holt A, Lewis KD, Plajzer-Frick I, Akiyama J, De Val S, Afzal V, Black BL, Couronne O, Eisen MB, Visel A, Rubin EM. PMID: 17086198.
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    161. A distal enhancer and an ultraconserved exon are derived from a novel retroposon. Nature. 2006 May 04; 441(7089):87-90. Bejerano G, Lowe CB, Ahituv N, King B, Siepel A, Salama SR, Rubin EM, Kent WJ, Haussler D. PMID: 16625209.
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    164. Comparative genomic analysis reveals a distant liver enhancer upstream of the COUP-TFII gene. Mamm Genome. 2005 Feb; 16(2):91-5. Baroukh N, Ahituv N, Chang J, Shoukry M, Afzal V, Rubin EM, Pennacchio LA. PMID: 15859353.
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