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Christopher Pilcher

Title(s)Professor Emeritus, Medicine
SchoolSchool of Medicine
Address1001 Potrero Ave
San Francisco CA 94110
Phone415-476-4082 ext. 403
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    Collapse Biography 
    Collapse Education and Training
    Harvard UniversityAB1986Biology
    University of Vermont College of MedicineMD1993Medicine
    Oxford University John Radcliffe HospitalSenior House Officer1996Paediatrics
    Duke University Medical CenterResidency1997Internal Medicine and Pediatrics
    University of North Carolina at Chapel HillFellowship2000Infectious Diseases

    Collapse Overview 
    Collapse Overview
    Dr. Christopher D. Pilcher is Professor in the Department of Medicine, Division of HIV, Infectious Diseases and Global Medicine, at UCSF and Zuckerberg SF General Hospital. He trained at the University of Vermont, Duke University and the University of North Carolina at Chapel Hill; he is board certified in Internal Medicine, Pediatrics and Infectious Diseases, and has been caring for adults with HIV infection since 1993.
    As a research scientist, Dr. Pilcher has authored over a hundred scholarly articles, book chapters and commentaries. He is a recognized authority on using infectious disease diagnostic tests for clinical decision making and surveillance of incidence. His work has focused on diagnosis of acute HIV infection; the same-day initiation of antiretroviral treatment; and the biology of infectivity in both acute and chronic HIV infection.
    Dr. Pilcher developed and led cohort studies in the US, Malawi and Brazil to facilitate clinical research, and most recently worked to develop the international CEPHIA 2 cohort for incidence test evaluation. In work with public health programs in North Carolina he developed the STAT program for acute HIV testing and immediate treatment; from 2012 in San Francisco he led the UCSF Options cohort, and in 2013 he began the RAPID program for same-day antiretroviral treatment at Zuckerberg SF General Hospital.
    Dr. Pilcher retired in 2019 but remains actively engaged in clinical research.

    Collapse Research 
    Collapse Research Activities and Funding
    A Pilot of Intervention to Promote Acute HIV Testing by Ambulatory Care Providers
    NIH/NIMH R34MH096606Sep 7, 2012 - Jun 30, 2015
    Role: Principal Investigator
    Host Factors Influencing HIV Viral Load and Infectivity in Semen
    NIH/NICHD R01HD074511Jul 25, 2012 - May 31, 2017
    Role: Principal Investigator
    Targeting Acute HIV
    NIH/NIMH R01MH068686Sep 19, 2003 - Oct 31, 2006
    Role: Principal Investigator
    CYTOREDUCTIVE CHEMOTHERAPY TARGETING HIV RESERVOIRS
    NIH/NIAID K23AI001781Jul 1, 2000 - Jun 30, 2005
    Role: Principal Investigator
    General Clinical Research Center
    NIH M01RR000046Oct 1, 1974 - May 31, 2008
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Global Health

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Group Testing for Severe Acute Respiratory Syndrome- Coronavirus 2 to Enable Rapid Scale-up of Testing and Real-Time Surveillance of Incidence. J Infect Dis. 2020 08 17; 222(6):903-909. Pilcher CD, Westreich D, Hudgens MG. PMID: 32592581.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsPHPublic Health
    2. Seminal Plasma-Derived Extracellular-Vesicle Fractions from HIV-Infected Men Exhibit Unique MicroRNA Signatures and Induce a Proinflammatory Response in Cells Isolated from the Female Reproductive Tract. J Virol. 2020 Jul 30; 94(16). Marques de Menezes EG, Jang K, George AF, Nyegaard M, Neidleman J, Inglis HC, Danesh A, Deng X, Afshari A, Kim YH, Billaud JN, Marson K, Pilcher CD, Pillai SK, Norris PJ, Roan NR. PMID: 32434889.
      View in: PubMed   Mentions:    Fields:    
    3. Semen virome of men with HIV on or off antiretroviral treatment. AIDS. 2020 05 01; 34(6):827-832. Li Y, Altan E, Pilcher C, Hartogensis W, Hecht FM, Deng X, Delwart E. PMID: 32271249.
      View in: PubMed   Mentions:    Fields:    
    4. Seminal plasma promotes decidualization of endometrial stromal fibroblasts in vitro from women with and without inflammatory disorders in a manner dependent on interleukin-11 signaling. Hum Reprod. 2020 Mar 27; 35(3):617-640. George AF, Jang KS, Nyegaard M, Neidleman J, Spitzer TL, Xie G, Chen JC, Herzig E, Laustsen A, Marques de Menezes EG, Houshdaran S, Pilcher CD, Norris PJ, Jakobsen MR, Greene WC, Giudice LC, Roan NR. PMID: 32219408.
      View in: PubMed   Mentions:    Fields:    
    5. Clinical and Immunologic Outcomes after Immediate or Deferred Antiretroviral Therapy Initiation during Primary HIV Infection: The Sabes Randomized Clinical Study. Clin Infect Dis. 2020 Feb 28. Lama JR, Ignacio RAB, Alfaro R, Rios J, Cartagena JG, Valdez R, Bain C, Barbarán KS, Villaran MV, Pilcher CD, Gonzales P, Sanchez J, Duerr A. PMID: 32107526.
      View in: PubMed   Mentions:    Fields:    
    6. Interpreting HIV diagnostic histories into infection time estimates: analytical framework and online tool. BMC Infect Dis. 2019 Oct 26; 19(1):894. Grebe E, Facente SN, Bingham J, Pilcher CD, Powrie A, Gerber J, Priede G, Chibawara T, Busch MP, Murphy G, Kassanjee R, Welte A. PMID: 31655566.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    7. Some Aspects of CD8+ T-Cell Exhaustion Are Associated With Altered T-Cell Mitochondrial Features and ROS Content in HIV Infection. J Acquir Immune Defic Syndr. 2019 10 01; 82(2):211-219. Deguit CDT, Hough M, Hoh R, Krone M, Pilcher CD, Martin JN, Deeks SG, McCune JM, Hunt PW, Rutishauser RL. PMID: 31513075.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    8. Performance comparison of the Maxim and Sedia Limiting Antigen Avidity assays for HIV incidence surveillance. PLoS One. 2019; 14(7):e0220345. Sempa JB, Welte A, Busch MP, Hall J, Hampton D, Facente SN, Keating SM, Marson K, Parkin N, Pilcher CD, Murphy G, Grebe E. PMID: 31348809.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCellsPHPublic Health
    9. Challenges to the performance of current HIV diagnostic assays and the need for centralized specimen archives: a review of the Consortium for the Evaluation and Performance of HIV Incidence Assays (CEPHIA) repository. Gates Open Res. 2019; 3:1511. Facente SN, Busch MP, Grebe E, Pilcher CD, Welte A, Rice B, Murphy G. PMID: 31460496.
      View in: PubMed   Mentions:
    10. A generalizable method for estimating duration of HIV infections using clinical testing history and HIV test results. AIDS. 2019 06 01; 33(7):1231-1240. Pilcher CD, Porco TC, Facente SN, Grebe E, Delaney KP, Masciotra S, Kassanjee R, Busch MP, Murphy G, Owen SM, Welte A. PMID: 30870196.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    11. RAPID antiretroviral therapy: high virologic suppression rates with immediate antiretroviral therapy initiation in a vulnerable urban clinic population. AIDS. 2019 04 01; 33(5):825-832. Coffey S, Bacchetti P, Sachdev D, Bacon O, Jones D, Ospina-Norvell C, Torres S, Lynch E, Camp C, Mercer-Slomoff R, Lee S, Christopoulos K, Pilcher C, Hsu L, Jin C, Scheer S, Havlir D, Gandhi M. PMID: 30882490.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansPHPublic Health
    12. Computational analysis of antibody dynamics identifies recent HIV-1 infection. JCI Insight. 2017 12 21; 2(24). Seaton KE, Vandergrift NA, Deal AW, Rountree W, Bainbridge J, Grebe E, Anderson DA, Sawant S, Shen X, Yates NL, Denny TN, Liao HX, Haynes BF, Robb ML, Parkin N, Santos BR, Garrett N, Price MA, Naniche D, Duerr AC, Keating S, Hampton D, Facente S, Marson K, Welte A, Pilcher CD, Cohen MS, Tomaras GD. PMID: 29263306.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    13. Infection Staging and Incidence Surveillance Applications of High Dynamic Range Diagnostic Immuno-Assay Platforms. J Acquir Immune Defic Syndr. 2017 12 15; 76(5):547-555. Grebe E, Welte A, Hall J, Keating SM, Facente SN, Marson K, Martin JN, Little SJ, Price MA, Kallas EG, Busch MP, Pilcher CD, Murphy G. PMID: 28914669.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCellsPHPublic Health
    14. Anti-HERV-K (HML-2) capsid antibody responses in HIV elite controllers. Retrovirology. 2017 Aug 22; 14(1):41. de Mulder M, SenGupta D, Deeks SG, Martin JN, Pilcher CD, Hecht FM, Sacha JB, Nixon DF, Michaud HA. PMID: 28830571.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    15. HIV Antibody Level as a Marker of HIV Persistence and Low-Level Viral Replication. J Infect Dis. 2017 07 01; 216(1):72-81. Keating SM, Pilcher CD, Jain V, Lebedeva M, Hampton D, Abdel-Mohsen M, Deng X, Murphy G, Welte A, Facente SN, Hecht F, Deeks SG, Pillai SK, Busch MP. PMID: 28498985.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    16. Clinical and public health implications of acute and early HIV detection and treatment: a scoping review. J Int AIDS Soc. 2017 06 28; 20(1):21579. Rutstein SE, Ananworanich J, Fidler S, Johnson C, Sanders EJ, Sued O, Saez-Cirion A, Pilcher CD, Fraser C, Cohen MS, Vitoria M, Doherty M, Tucker JD. PMID: 28691435.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansPHPublic Health
    17. Semen amyloids participate in spermatozoa selection and clearance. Elife. 2017 06 27; 6. Roan NR, Sandi-Monroy N, Kohgadai N, Usmani SM, Hamil KG, Neidleman J, Montano M, Ständker L, Röcker A, Cavrois M, Rosen J, Marson K, Smith JF, Pilcher CD, Gagsteiger F, Sakk O, O'Rand M, Lishko PV, Kirchhoff F, Münch J, Greene WC. PMID: 28653619.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    18. Early and Delayed Antiretroviral Therapy Results in Comparable Reductions in CD8+ T Cell Exhaustion Marker Expression. AIDS Res Hum Retroviruses. 2017 07; 33(7):658-667. Rutishauser RL, Hartogensis W, Deguit CD, Krone M, Hoh R, Hecht FM, Pilcher CD, Bacchetti P, Deeks SG, Hunt PW, McCune JM. PMID: 28335609.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCellsPHPublic Health
    19. Real-world performance of the new US HIV testing algorithm in medical settings. J Clin Virol. 2017 06; 91:73-78. Marson KG, Marlin R, Pham P, Cohen SE, Jones D, Roemer M, Peters PJ, Haller B, Pilcher CD. PMID: 28434809.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansPHPublic Health
    20. Limitations of using the Lorenz curve framework to understand the distribution of population viral load: authors' reply. AIDS. 2017 03 13; 31(5):742-743. Christopoulos KA, Hartogensis W, Glidden DV, Pilcher CD, Gandhi M, Geng EH. PMID: 28225455.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    21. Comparison of cross-sectional HIV incidence assay results from dried blood spots and plasma. PLoS One. 2017; 12(2):e0172283. Schlusser KE, Pilcher C, Kallas EG, Santos BR, Deeks SG, Facente S, Keating SM, Busch MP, Murphy G, Welte A, Quinn T, Eshleman SH, Laeyendecker O. PMID: 28231277.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    22. The Lorenz curve: a novel method for understanding viral load distribution at the population level. AIDS. 2017 01 14; 31(2):309-310. Christopoulos KA, Hartogensis W, Glidden DV, Pilcher CD, Gandhi M, Geng EH. PMID: 27831945.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    23. The Effect of Same-Day Observed Initiation of Antiretroviral Therapy on HIV Viral Load and Treatment Outcomes in a US Public Health Setting. J Acquir Immune Defic Syndr. 2017 Jan 01; 74(1):44-51. Pilcher CD, Ospina-Norvell C, Dasgupta A, Jones D, Hartogensis W, Torres S, Calderon F, Demicco E, Geng E, Gandhi M, Havlir DV, Hatano H. PMID: 27434707.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    24. Performance of the Bio-Rad Geenius HIV1/2 Supplemental Assay in Detecting "Recent" HIV Infection and Calculating Population Incidence. J Acquir Immune Defic Syndr. 2016 Dec 15; 73(5):581-588. Keating SM, Kassanjee R, Lebedeva M, Facente SN, MacArthur JC, Grebe E, Murphy G, Welte A, Martin JN, Little S, Price MA, Kallas EG, Busch MP, Pilcher CD. PMID: 27509247.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    25. Viral load criteria and threshold optimization to improve HIV incidence assay characteristics. AIDS. 2016 09 24; 30(15):2361-71. Kassanjee R, Pilcher CD, Busch MP, Murphy G, Facente SN, Keating SM, Mckinney E, Marson K, Price MA, Martin JN, Little SJ, Hecht FM, Kallas EG, Welte A. PMID: 27454561.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    26. Editorial Commentary: Timing Is Everything: Shortcomings of Current HIV Diagnostics in the Early Treatment Era. Clin Infect Dis. 2016 08 15; 63(4):562-4. Keating SM, Pilcher CD, Busch MP. PMID: 27317798.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    27. Selection of a potential diagnostic biomarker for HIV infection from a random library of non-biological synthetic peptoid oligomers. J Immunol Methods. 2016 08; 435:85-9. Gearhart TL, Montelaro RC, Schurdak ME, Pilcher CD, Rinaldo CR, Kodadek T, Park Y, Islam K, Yurko R, Marques ET, Burke DS. PMID: 27182050.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    28. Efficient Identification of HIV Serodiscordant Couples by Existing HIV Testing Programs in South Brazil. PLoS One. 2015; 10(11):e0142638. Pilcher CD, Bisol CA, Paganella MP, Vallabhaneni S, da Motta LR, Kato SK, Sperhacke RD, Kallas EG, Hecht FM, Diaz RS. PMID: 26562436.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    29. Gut-Resident Lactobacillus Abundance Associates with IDO1 Inhibition and Th17 Dynamics in SIV-Infected Macaques. Cell Rep. 2015 Nov 24; 13(8):1589-97. Vujkovic-Cvijin I, Swainson LA, Chu SN, Ortiz AM, Santee CA, Petriello A, Dunham RM, Fadrosh DW, Lin DL, Faruqi AA, Huang Y, Apetrei C, Pandrea I, Hecht FM, Pilcher CD, Klatt NR, Brenchley JM, Lynch SV, McCune JM. PMID: 26586432.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    30. Newly Exerted T Cell Pressures on Mutated Epitopes following Transmission Help Maintain Consensus HIV-1 Sequences. PLoS One. 2014; 10(4):e0120787. Eriksson EM, Liegler T, Keh CE, Karlsson AC, Holditch SJ, Pilcher CD, Loeb L, Nixon DF, Hecht FM. PMID: 25919393.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    31. Longitudinal Genetic Characterization Reveals That Cell Proliferation Maintains a Persistent HIV Type 1 DNA Pool During Effective HIV Therapy. J Infect Dis. 2015 Aug 15; 212(4):596-607. von Stockenstrom S, Odevall L, Lee E, Sinclair E, Bacchetti P, Killian M, Epling L, Shao W, Hoh R, Ho T, Faria NR, Lemey P, Albert J, Hunt P, Loeb L, Pilcher C, Poole L, Hatano H, Somsouk M, Douek D, Boritz E, Deeks SG, Hecht FM, Palmer S. PMID: 25712966.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansCells
    32. Select host restriction factors are associated with HIV persistence during antiretroviral therapy. AIDS. 2015 Feb 20; 29(4):411-20. Abdel-Mohsen M, Wang C, Strain MC, Lada SM, Deng X, Cockerham LR, Pilcher CD, Hecht FM, Liegler T, Richman DD, Deeks SG, Pillai SK. PMID: 25602681.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    33. How can we better identify early HIV infections? Curr Opin HIV AIDS. 2015 Jan; 10(1):61-8. Rosenberg NE, Pilcher CD, Busch MP, Cohen MS. PMID: 25389806.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    34. High Transmissibility During Early HIV Infection Among Men Who Have Sex With Men-San Francisco, California. J Infect Dis. 2015 Jun 01; 211(11):1757-60. Hollingsworth TD, Pilcher CD, Hecht FM, Deeks SG, Fraser C. PMID: 25542958.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    35. Independent assessment of candidate HIV incidence assays on specimens in the CEPHIA repository. AIDS. 2014 Oct 23; 28(16):2439-49. Kassanjee R, Pilcher CD, Keating SM, Facente SN, McKinney E, Price MA, Martin JN, Little S, Hecht FM, Kallas EG, Welte A, Busch MP, Murphy G. PMID: 25144218.
      View in: PubMed   Mentions: 52     Fields:    Translation:Humans
    36. Programmed death-1 expression on CD4? and CD8? T cells in treated and untreated HIV disease. AIDS. 2014 Jul 31; 28(12):1749-58. Cockerham LR, Jain V, Sinclair E, Glidden DV, Hartogenesis W, Hatano H, Hunt PW, Martin JN, Pilcher CD, Sekaly R, McCune JM, Hecht FM, Deeks SG. PMID: 24871455.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    37. Dynamic regulation of host restriction factor expression over the course of HIV-1 infection in vivo. J Virol. 2014 Oct; 88(19):11624-9. Raposo RA, Abdel-Mohsen M, Deng X, Hecht FM, Pilcher CD, Pillai SK, Nixon DF. PMID: 25031350.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    38. Decreased HIV type 1 transcription in CCR5-?32 heterozygotes during suppressive antiretroviral therapy. J Infect Dis. 2014 Dec 01; 210(11):1838-43. Wang C, Abdel-Mohsen M, Strain MC, Lada SM, Yukl S, Cockerham LR, Pilcher CD, Hecht FM, Sinclair E, Liegler T, Richman DD, Deeks SG, Pillai SK. PMID: 24935955.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    39. Longitudinal characterization of depression and mood states beginning in primary HIV infection. AIDS Behav. 2014 Jun; 18(6):1124-32. Gold JA, Grill M, Peterson J, Pilcher C, Lee E, Hecht FM, Fuchs D, Yiannoutsos CT, Price RW, Robertson K, Spudich S. PMID: 24385231.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    40. Direct visualization of HIV-enhancing endogenous amyloid fibrils in human semen. Nat Commun. 2014 Apr 01; 5:3508. Usmani SM, Zirafi O, Müller JA, Sandi-Monroy NL, Yadav JK, Meier C, Weil T, Roan NR, Greene WC, Walther P, Nilsson KP, Hammarström P, Wetzel R, Pilcher CD, Gagsteiger F, Fändrich M, Kirchhoff F, Münch J. PMID: 24691351.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    41. Toward an endgame: finding and engaging people unaware of their HIV-1 infection in treatment and prevention. AIDS Res Hum Retroviruses. 2014 Mar; 30(3):217-24. Burns DN, DeGruttola V, Pilcher CD, Kretzschmar M, Gordon CM, Flanagan EH, Duncombe C, Cohen MS. PMID: 24410300.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    42. Trans-activation, post-transcriptional maturation, and induction of antibodies to HERV-K (HML-2) envelope transmembrane protein in HIV-1 infection. Retrovirology. 2014 Jan 28; 11:10. Michaud HA, de Mulder M, SenGupta D, Deeks SG, Martin JN, Pilcher CD, Hecht FM, Sacha JB, Nixon DF. PMID: 24472118.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    43. Performance of rapid point-of-care and laboratory tests for acute and established HIV infection in San Francisco. PLoS One. 2013; 8(12):e80629. Pilcher CD, Louie B, Facente S, Keating S, Hackett J, Vallari A, Hall C, Dowling T, Busch MP, Klausner JD, Hecht FM, Liska S, Pandori MW. PMID: 24349007.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    44. HIV-1 Vif adaptation to human APOBEC3H haplotypes. Cell Host Microbe. 2013 Oct 16; 14(4):411-21. Ooms M, Brayton B, Letko M, Maio SM, Pilcher CD, Hecht FM, Barbour JD, Simon V. PMID: 24139399.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    45. Activation associated ERK1/2 signaling impairments in CD8+ T cells co-localize with blunted polyclonal and HIV-1 specific effector functions in early untreated HIV-1 infection. PLoS One. 2013; 8(10):e77412. Crawford TQ, Hecht FM, Pilcher CD, Ndhlovu LC, Barbour JD. PMID: 24143233.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    46. HIV-associated disruption of mucosal epithelium facilitates paracellular penetration by human papillomavirus. Virology. 2013 Nov; 446(1-2):378-88. Tugizov SM, Herrera R, Chin-Hong P, Veluppillai P, Greenspan D, Michael Berry J, Pilcher CD, Shiboski CH, Jay N, Rubin M, Chein A, Palefsky JM. PMID: 24074602.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    47. Patient perspectives on the experience of being newly diagnosed with HIV in the emergency department/urgent care clinic of a public hospital. PLoS One. 2013; 8(8):e74199. Christopoulos KA, Massey AD, Lopez AM, Hare CB, Johnson MO, Pilcher CD, Fielding H, Dawson-Rose C. PMID: 23991214.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    48. Antiretroviral therapy initiated within 6 months of HIV infection is associated with lower T-cell activation and smaller HIV reservoir size. J Infect Dis. 2013 Oct 15; 208(8):1202-11. Jain V, Hartogensis W, Bacchetti P, Hunt PW, Hatano H, Sinclair E, Epling L, Lee TH, Busch MP, McCune JM, Pilcher CD, Hecht FM, Deeks SG. PMID: 23852127.
      View in: PubMed   Mentions: 128     Fields:    Translation:HumansCells
    49. Challenges in detecting HIV persistence during potentially curative interventions: a study of the Berlin patient. PLoS Pathog. 2013; 9(5):e1003347. Yukl SA, Boritz E, Busch M, Bentsen C, Chun TW, Douek D, Eisele E, Haase A, Ho YC, Hütter G, Justement JS, Keating S, Lee TH, Li P, Murray D, Palmer S, Pilcher C, Pillai S, Price RW, Rothenberger M, Schacker T, Siliciano J, Siliciano R, Sinclair E, Strain M, Wong J, Richman D, Deeks SG. PMID: 23671416.
      View in: PubMed   Mentions: 113     Fields:    Translation:HumansCellsCTClinical Trials
    50. "Taking a half day at a time:" patient perspectives and the HIV engagement in care continuum. AIDS Patient Care STDS. 2013 Apr; 27(4):223-30. Christopoulos KA, Massey AD, Lopez AM, Geng EH, Johnson MO, Pilcher CD, Fielding H, Dawson-Rose C. PMID: 23565926.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    51. T cells target APOBEC3 proteins in human immunodeficiency virus type 1-infected humans and simian immunodeficiency virus-infected Indian rhesus macaques. J Virol. 2013 Jun; 87(11):6073-80. Champiat S, Garrison KE, Raposo RA, Burwitz BJ, Reed J, Tandon R, York VA, Newman LP, Nimityongskul FA, Wilson NA, Almeida RR, Martin JN, Deeks SG, Rosenberg MG, Wiznia AA, Spotts GE, Pilcher CD, Hecht FM, Ostrowski MA, Sacha JB, Nixon DF. PMID: 23536679.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    52. Changes in seroadaptive practices from before to after diagnosis of recent HIV infection among men who have sex with men. PLoS One. 2013; 8(2):e55397. Vallabhaneni S, McConnell JJ, Loeb L, Hartogensis W, Hecht FM, Grant RM, Pilcher CD. PMID: 23405145.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    53. Leveraging a rapid, round-the-clock HIV testing system to screen for acute HIV infection in a large urban public medical center. J Acquir Immune Defic Syndr. 2013 Feb 01; 62(2):e30-8. Christopoulos KA, Zetola NM, Klausner JD, Haller B, Louie B, Hare CB, Pandori M, Nassos P, Roemer M, Pilcher CD. PMID: 23117503.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    54. Seroadaptive practices: association with HIV acquisition among HIV-negative men who have sex with men. PLoS One. 2012; 7(10):e45718. Vallabhaneni S, Li X, Vittinghoff E, Donnell D, Pilcher CD, Buchbinder SP. PMID: 23056215.
      View in: PubMed   Mentions: 44     Fields:    Translation:Humans
    55. Influence of HAART on alternative reading frame immune responses over the course of HIV-1 infection. PLoS One. 2012; 7(6):e39311. Champiat S, Raposo RA, Maness NJ, Lehman JL, Purtell SE, Hasenkrug AM, Miller JC, Dean H, Koff WC, Hong MA, Martin JN, Deeks SG, Spotts GE, Pilcher CD, Hecht FM, Kallas EG, Garrison KE, Nixon DF. PMID: 22768072.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    56. Adjusting for sampling variability in sparse data: geostatistical approaches to disease mapping. Int J Health Geogr. 2011 Oct 06; 10:54. Hampton KH, Serre ML, Gesink DC, Pilcher CD, Miller WC. PMID: 21978359.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansPHPublic Health
    57. Identifying the early post-HIV antibody seroconversion period. J Infect Dis. 2011 Aug 15; 204(4):526-33. Hecht FM, Wellman R, Busch MP, Pilcher CD, Norris PJ, Margolick JB, Collier AC, Little SJ, Markowitz M, Routy JP, Holte S. PMID: 21791654.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    58. Performance of risk-based criteria for targeting acute HIV screening in San Francisco. PLoS One. 2011; 6(7):e21813. Facente SN, Pilcher CD, Hartogensis WE, Klausner JD, Philip SS, Louie B, Christopoulos KA, Dowling T, Colfax GN. PMID: 21755003.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCellsPHPublic Health
    59. Sexual partnership patterns in malawi: implications for HIV/STI transmission. Sex Transm Dis. 2011 Jul; 38(7):657-66. Powers KA, Hoffman IF, Ghani AC, Hosseinipour MC, Pilcher CD, Price MA, Pettifor AE, Chilongozi DA, Martinson FE, Cohen MS, Miller WC. PMID: 21301383.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    60. Differential persistence of transmitted HIV-1 drug resistance mutation classes. J Infect Dis. 2011 Apr 15; 203(8):1174-81. Jain V, Sucupira MC, Bacchetti P, Hartogensis W, Diaz RS, Kallas EG, Janini LM, Liegler T, Pilcher CD, Grant RM, Cortes R, Deeks SG, Hecht FM. PMID: 21451005.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansCells
    61. Transmitted drug resistance in persons with acute/early HIV-1 in San Francisco, 2002-2009. PLoS One. 2010 Dec 10; 5(12):e15510. Jain V, Liegler T, Vittinghoff E, Hartogensis W, Bacchetti P, Poole L, Loeb L, Pilcher CD, Grant RM, Deeks SG, Hecht FM. PMID: 21170322.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    62. Beyond detuning: 10 years of progress and new challenges in the development and application of assays for HIV incidence estimation. AIDS. 2010 Nov 27; 24(18):2763-71. Busch MP, Pilcher CD, Mastro TD, Kaldor J, Vercauteren G, Rodriguez W, Rousseau C, Rehle TM, Welte A, Averill MD, Garcia Calleja JM. PMID: 20975514.
      View in: PubMed   Mentions: 71     Fields:    Translation:HumansPHPublic Health
    63. PCR-based pooling of dried blood spots for detection of malaria parasites: optimization and application to a cohort of Ugandan children. J Clin Microbiol. 2010 Oct; 48(10):3539-43. Hsiang MS, Lin M, Dokomajilar C, Kemere J, Pilcher CD, Dorsey G, Greenhouse B. PMID: 20686079.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    64. Acute HIV-1 infection is highly prevalent in Ugandan adults with suspected malaria. AIDS. 2010 Jul 31; 24(12):1945-52. Bebell LM, Pilcher CD, Dorsey G, Havlir D, Kamya MR, Busch MP, Dunn Williams J, Nugent CT, Bentsen C, Rosenthal PJ, Charlebois ED. PMID: 20543656.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    65. Public health rationale for rapid nucleic acid or p24 antigen tests for HIV. J Infect Dis. 2010 Apr 15; 201 Suppl 1:S7-15. Pilcher CD, Christopoulos KA, Golden M. PMID: 20225950.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    66. Oral cyclosporin A inhibits CD4 T cell P-glycoprotein activity in HIV-infected adults initiating treatment with nucleoside reverse transcriptase inhibitors. Eur J Clin Pharmacol. 2009 Nov; 65(11):1081-8. Hulgan T, Donahue JP, Smeaton L, Pu M, Wang H, Lederman MM, Smith K, Valdez H, Pilcher C, Haas DW. PMID: 19779705.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    67. Sexually transmitted infections among patients with acute HIV in North Carolina. Sex Transm Dis. 2009 Jun; 36(6):372-4. McCoy SI, Eron JJ, Kuruc JD, Strauss RP, Macdonald PD, Fiscus SA, Barnhart J, Pilcher CD, Leone PA, Miller WC. PMID: 19387421.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    68. Targeted testing for acute HIV infection in North Carolina. AIDS. 2009 Apr 27; 23(7):835-43. Miller WC, Leone PA, McCoy S, Nguyen TQ, Williams DE, Pilcher CD. PMID: 19318909.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCellsPHPublic Health
    69. Transmitted antiretroviral drug resistance among acute and recent HIV infections in North Carolina from 1998 to 2007. Antivir Ther. 2009; 14(5):673-8. Hurt CB, McCoy SI, Kuruc J, Nelson JA, Kerkau M, Fiscus S, McGee K, Sebastian J, Leone P, Pilcher C, Hicks C, Eron J. PMID: 19704170.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCellsPHPublic Health
    70. The deadliest catch: fishing for HIV in new waters. Ann Intern Med. 2008 Aug 05; 149(3):204-5. Pilcher CD, Hare CB. PMID: 18678848.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    71. Optimizing screening for acute human immunodeficiency virus infection with pooled nucleic acid amplification tests. J Clin Microbiol. 2008 May; 46(5):1785-92. Westreich DJ, Hudgens MG, Fiscus SA, Pilcher CD. PMID: 18353930.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCellsPHPublic Health
    72. Inferring HIV transmission dynamics from phylogenetic sequence relationships. PLoS Med. 2008 Mar 18; 5(3):e69. Pilcher CD, Wong JK, Pillai SK. PMID: 18351799.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    73. Clinical presentation and diagnosis of primary HIV-1 infection. Curr Opin HIV AIDS. 2008 Jan; 3(1):10-5. Daar ES, Pilcher CD, Hecht FM. PMID: 19372938.
      View in: PubMed   Mentions: 16     Fields:    
    74. Frequent detection of acute HIV infection in pregnant women. AIDS. 2007 Nov 12; 21(17):2303-8. Patterson KB, Leone PA, Fiscus SA, Kuruc J, McCoy SI, Wolf L, Foust E, Williams D, Eron JJ, Pilcher CD. PMID: 18090278.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCellsPHPublic Health
    75. Improved detection of acute HIV-1 infection in sub-Saharan Africa: development of a risk score algorithm. AIDS. 2007 Oct 18; 21(16):2237-42. Powers KA, Miller WC, Pilcher CD, Mapanje C, Martinson FE, Fiscus SA, Chilongozi DA, Namakhwa D, Price MA, Galvin SR, Hoffman IF, Cohen MS. PMID: 18090052.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    76. Amplified transmission of HIV-1: comparison of HIV-1 concentrations in semen and blood during acute and chronic infection. AIDS. 2007 Aug 20; 21(13):1723-30. Pilcher CD, Joaki G, Hoffman IF, Martinson FE, Mapanje C, Stewart PW, Powers KA, Galvin S, Chilongozi D, Gama S, Price MA, Fiscus SA, Cohen MS. PMID: 17690570.
      View in: PubMed   Mentions: 124     Fields:    Translation:HumansCells
    77. Comparison of group testing algorithms for case identification in the presence of test error. Biometrics. 2007 Dec; 63(4):1152-63. Kim HY, Hudgens MG, Dreyfuss JM, Westreich DJ, Pilcher CD. PMID: 17501946.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansPHPublic Health
    78. Intensification of a triple-nucleoside regimen with tenofovir or efavirenz in HIV-1-infected patients with virological suppression. AIDS. 2007 Apr 23; 21(7):813-23. Gulick RM, Lalama CM, Ribaudo HJ, Shikuma CM, Schackman BR, Schouten J, Squires KE, Koletar SL, Pilcher CD, Reichman RC, Klingman KL, Kuritzkes DR. PMID: 17415036.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    79. Diagnosis and management of acute HIV infection. Infect Dis Clin North Am. 2007 Mar; 21(1):19-48, vii. Zetola NM, Pilcher CD. PMID: 17502228.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    80. Lessons from primary HIV infection. Focus. 2007 Feb; 22(2):1-5. Hecht F, Pilcher C. PMID: 17549830.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    81. Detection of acute HIV infections in an urban HIV counseling and testing population in the United States. J Acquir Immune Defic Syndr. 2007 Feb 01; 44(2):196-202. Priddy FH, Pilcher CD, Moore RH, Tambe P, Park MN, Fiscus SA, Feinberg MB, del Rio C. PMID: 17312561.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    82. Rapid, real-time detection of acute HIV infection in patients in Africa. J Infect Dis. 2007 Feb 01; 195(3):416-24. Fiscus SA, Pilcher CD, Miller WC, Powers KA, Hoffman IF, Price M, Chilongozi DA, Mapanje C, Krysiak R, Gama S, Martinson FE, Cohen MS. PMID: 17205481.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCells
    83. Acute HIV revisited: new opportunities for treatment and prevention. Journal of Clinical Investigation. 2006 Dec 1; 116(12):3292-3292. Christopher D. Pilcher, Joseph J. Eron, Shannon Galvin, Cynthia Gay, Myron S. Cohen. .
      View in: Publisher Site   Mentions:
    84. A randomized, partially blinded phase 2 trial of antiretroviral therapy, HIV-specific immunizations, and interleukin-2 cycles to promote efficient control of viral replication (ACTG A5024). J Infect Dis. 2006 Dec 15; 194(12):1672-6. Kilby JM, Bucy RP, Mildvan D, Fischl M, Santana-Bagur J, Lennox J, Pilcher C, Zolopa A, Lawrence J, Pollard RB, Habib RE, Sahner D, Fox L, Aga E, Bosch RJ, Mitsuyasu R. PMID: 17109338.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
    85. Approaching "HIV elimination": interventions for acute HIV infection. Curr HIV/AIDS Rep. 2006 Nov; 3(4):160-8. Pilcher CD, Eaton L, Kalichman S, Bisol C, de Souza Rda S. PMID: 17032575.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCellsPHPublic Health
    86. Three- vs four-drug antiretroviral regimens for the initial treatment of HIV-1 infection: a randomized controlled trial. JAMA. 2006 Aug 16; 296(7):769-81. Gulick RM, Ribaudo HJ, Shikuma CM, Lalama C, Schackman BR, Meyer WA, Acosta EP, Schouten J, Squires KE, Pilcher CD, Murphy RL, Koletar SL, Carlson M, Reichman RC, Bastow B, Klingman KL, Kuritzkes DR. PMID: 16905783.
      View in: PubMed   Mentions: 80     Fields:    Translation:HumansCells
    87. Amplified HIV Transmission: The Missing Link in the HIV Pandemic?. Retrovirology. 2005 Dec 1; 2(Suppl 1):s57. MS Cohen, C Pilcher, JJ Eron, PA Leone, SA Fiscus, R Swanstrom. .
      View in: Publisher Site   Mentions:
    88. Detection of acute infections during HIV testing in North Carolina. N Engl J Med. 2005 May 05; 352(18):1873-83. Pilcher CD, Fiscus SA, Nguyen TQ, Foust E, Wolf L, Williams D, Ashby R, O'Dowd JO, McPherson JT, Stalzer B, Hightow L, Miller WC, Eron JJ, Cohen MS, Leone PA. PMID: 15872202.
      View in: PubMed   Mentions: 139     Fields:    Translation:HumansCellsPHPublic Health
    89. Surveillance for HIV-1 incidence using tests for recent infection in resource-constrained countries. AIDS. 2005 May; 19 Suppl 2:S25-30. McDougal JS, Pilcher CD, Parekh BS, Gershy-Damet G, Branson BM, Marsh K, Wiktor SZ. PMID: 15930838.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    90. The unexpected movement of the HIV epidemic in the Southeastern United States: transmission among college students. J Acquir Immune Defic Syndr. 2005 Apr 15; 38(5):531-7. Hightow LB, MacDonald PD, Pilcher CD, Kaplan AH, Foust E, Nguyen TQ, Leone PA. PMID: 15793362.
      View in: PubMed   Mentions: 39     Fields:    Translation:Humans
    91. Amplified HIV transmission and new approaches to HIV prevention. J Infect Dis. 2005 May 01; 191(9):1391-3. Cohen MS, Pilcher CD. PMID: 15809893.
      View in: PubMed   Mentions: 42     Fields:    Translation:Humans
    92. Multiple V1/V2 env variants are frequently present during primary infection with human immunodeficiency virus type 1. J Virol. 2004 Oct; 78(20):11208-18. Ritola K, Pilcher CD, Fiscus SA, Hoffman NG, Nelson JA, Kitrinos KM, Hicks CB, Eron JJ, Swanstrom R. PMID: 15452240.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansCells
    93. Triple-nucleoside regimens versus efavirenz-containing regimens for the initial treatment of HIV-1 infection. N Engl J Med. 2004 Apr 29; 350(18):1850-61. Gulick RM, Ribaudo HJ, Shikuma CM, Lustgarten S, Squires KE, Meyer WA, Acosta EP, Schackman BR, Pilcher CD, Murphy RL, Maher WE, Witt MD, Reichman RC, Snyder S, Klingman KL, Kuritzkes DR. PMID: 15115831.
      View in: PubMed   Mentions: 145     Fields:    Translation:HumansCellsCTClinical Trials
    94. Brief but efficient: acute HIV infection and the sexual transmission of HIV. J Infect Dis. 2004 May 15; 189(10):1785-92. Pilcher CD, Tien HC, Eron JJ, Vernazza PL, Leu SY, Stewart PW, Goh LE, Cohen MS. PMID: 15122514.
      View in: PubMed   Mentions: 237     Fields:    Translation:HumansCells
    95. Acute HIV revisited: new opportunities for treatment and prevention. J Clin Invest. 2004 Apr; 113(7):937-45. Pilcher CD, Eron JJ, Galvin S, Gay C, Cohen MS. PMID: 15057296.
      View in: PubMed   Mentions: 53     Fields:    Translation:Humans
    96. Absence of sustained hyperlactatemia in HIV-infected patients with risk factors for mitochondrial toxicity. J Acquir Immune Defic Syndr. 2004 Mar 01; 35(3):274-8. Wohl DA, Pilcher CD, Evans S, Revuelta M, McComsey G, Yang Y, Zackin R, Alston B, Welch S, Basar M, Kashuba A, Kondo P, Martinez A, Giardini J, Quinn J, Littles M, Wingfield H, Koletar SL. PMID: 15076242.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCellsCTClinical Trials
    97. HIV infection: point-of-care testing. Ann Pharmacother. 2004 Apr; 38(4):670-6. Donovan BJ, Rublein JC, Leone PA, Pilcher CD. PMID: 14990775.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    98. Frequent detection of acute primary HIV infection in men in Malawi. AIDS. 2004 Feb 20; 18(3):517-24. Pilcher CD, Price MA, Hoffman IF, Galvin S, Martinson FE, Kazembe PN, Eron JJ, Miller WC, Fiscus SA, Cohen MS. PMID: 15090805.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansCellsPHPublic Health
    99. Envelope diversity, coreceptor usage and syncytium-inducing phenotype of HIV-1 variants in saliva and blood during primary infection. AIDS. 2003 Sep 26; 17(14):2025-33. Freel SA, Fiscus SA, Pilcher CD, Menezes P, Giner J, Patrick E, Lennox JL, Hicks CB, Eron JJ, Shugars DC. PMID: 14502005.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    100. Infrequent diagnosis of primary human immunodeficiency virus infection: missed opportunities in acute care settings. Arch Intern Med. 2003 Sep 22; 163(17):2097-100. Weintrob AC, Giner J, Menezes P, Patrick E, Benjamin DK, Lennox J, Pilcher CD, Eron JJ, Hicks CB. PMID: 14504125.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    101. Real-time, universal screening for acute HIV infection in a routine HIV counseling and testing population. JAMA. 2002 Jul 10; 288(2):216-21. Pilcher CD, McPherson JT, Leone PA, Smurzynski M, Owen-O'Dowd J, Peace-Brewer AL, Harris J, Hicks CB, Eron JJ, Fiscus SA. PMID: 12095386.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCellsPHPublic Health
    102. Diagnosing primary HIV infection. Ann Intern Med. 2002 Mar 19; 136(6):488-9; author reply 488-9. Pilcher CD, Wohl DA, Hicks CB. PMID: 11900505.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    103. HIV antigens can induce TGF-beta(1)-producing immunoregulatory CD8+ T cells. J Immunol. 2002 Mar 01; 168(5):2247-54. Garba ML, Pilcher CD, Bingham AL, Eron J, Frelinger JA. PMID: 11859112.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansCells
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