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Matthew Spinelli, MD, MAS

Title(s)Clinical Fellow, Medicine
SchoolSchool of Medicine
Phone628-206-2400
ORCID ORCID Icon0000-0001-6368-8664 Additional info
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    Collapse Biography 
    Collapse Education and Training
    Columbia UniversityB.A.2008Italian Literature
    Mount Sinai School of MedicineM.D.2013Medicine
    University of California, San FranciscoResidency2016Internal Medicine
    University of California, San FranciscoFellowship2018Infectious Diseases
    University of California, San FranciscoM.A.S.2019Clinical Research & Implementation Science

    Collapse Overview 
    Collapse Overview
    I am interested in HIV/AIDS research with particular interest in HIV prevention, pre-exposure prophylaxis (PrEP) implementation, adherence, and PrEP persistence (remaining on PrEP over time). My research interests focus on factors affecting retention in care and PrEP persistence in domestic populations, particularly examining provider and systems factors that could improve PrEP persistence.

    Collapse Research 
    Collapse Research Activities and Funding
    PrEP Point-of-Care Brief-Intervention for Adherence among Young Men Who Have Sex with Men (PrEP2-BAY Study)
    NIH/NIMH K23MH122286Jan 24, 2020 - Dec 31, 2024
    Role: Principal Investigator

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    Collapse Featured Publications
    Collapse In The News

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Spinelli MA, Rodrigues WC, Wang G, Vincent M, Glidden DV, Okochi H, Stalter R, Defechereux P, Deutsch M, Grant RM, Ngure K, Mugo NR, Baeten JM, Gandhi M. HIGH ACCURACY OF A REAL-TIME URINE ANTIBODY-BASED TENOFOVIR POINT-OF-CARE TEST COMPARED TO LABORATORY-BASED ELISA IN DIVERSE POPULATIONS. J Acquir Immune Defic Syndr. 2020 Mar 10. PMID: 32167963.
      View in: PubMed
    2. Laborde ND, Kinley PM, Spinelli M, Vittinghoff E, Whitacre R, Scott HM, Buchbinder SP. Understanding PrEP Persistence: Provider and Patient Perspectives. AIDS Behav. 2020 Feb 11. PMID: 32048078.
      View in: PubMed
    3. Gandhi M, Wang G, King R, Rodrigues WC, Vincent M, Glidden DV, Cressey TR, Bacchetti P, Spinelli MA, Okochi H, Siriprakaisil O, Klinbuayaem V, Mugo NR, Ngure K, Drain PK, Baeten JM. Development and validation of the first point-of-care assay to objectively monitor adherence to HIV treatment and prevention in real-time in routine settings. AIDS. 2020 Feb 01; 34(2):255-260. PMID: 31634188.
      View in: PubMed
    4. Scott HM, Spinelli M, Vittinghoff E, Morehead-Gee A, Hirozawa A, James C, Hammer H, Liu A, Gandhi M, Buchbinder S. Racial/ethnic and HIV risk category disparities in preexposure prophylaxis discontinuation among patients in publicly funded primary care clinics. AIDS. 2019 Nov 15; 33(14):2189-2195. PMID: 31436610.
      View in: PubMed
    5. Spinelli MA, Buchbinder SP. PrEP Persistence is a Critical Issue in PrEP Implementation. Clin Infect Dis. 2019 Sep 12. PMID: 31509603.
      View in: PubMed
    6. Spinelli MA, Hessol NA, Schwarcz S, Hsu L, Parisi MK, Pipkin S, Scheer S, Havlir D, Buchbinder SP. Homelessness at diagnosis is associated with death among people with HIV in a population-based study of a US city. AIDS. 2019 09 01; 33(11):1789-1794. PMID: 31259765.
      View in: PubMed
    7. Spinelli MA, Glidden DV, Anderson PL, Gandhi M, McMahan VM, Defechereux P, Schechter M, Veloso VG, Chariyalertsak S, Guanira JV, Bekker LG, Buchbinder SP, Grant RM. Impact of Estimated Pre-Exposure Prophylaxis (PrEP) Adherence Patterns on Bone Mineral Density in a Large PrEP Demonstration Project. AIDS Res Hum Retroviruses. 2019 Sep; 35(9):788-793. PMID: 31119944.
      View in: PubMed
    8. Paul Drain, Kenneth Ngure, Nelly Mugo, Matthew Spinelli, Purba Chatterjee, Peter Bacchetti, David Glidden, Jared Baeten, Monica Gandhi. Testing a Real-Time Tenofovir Urine Adherence Assay for Monitoring and Providing Feedback to PrEP in Kenya (the PUMA study): A Pilot Randomized Clinical Trial (Preprint). JMIR Research Protocols. 2019 Jun 13.
      View in: Publisher Site
    9. Spinelli MA, Glidden DV, Anderson PL, Gandhi M, Cohen S, Vittinghoff E, Coleman ME, Scott H, Bacon O, Elion R, Kolber MA, Buchbinder SP, Liu AY. Brief Report: Short-Term Adherence Marker to PrEP Predicts Future Nonretention in a Large PrEP Demo Project: Implications for Point-of-Care Adherence Testing. J Acquir Immune Defic Syndr. 2019 06 01; 81(2):158-162. PMID: 31095005.
      View in: PubMed
    10. Gandhi M, Bacchetti P, Spinelli MA, Okochi H, Baeten JM, Siriprakaisil O, Klinbuayaem V, Rodrigues WC, Wang G, Vincent M, Cressey TR, Drain PK. Brief Report: Validation of a Urine Tenofovir Immunoassay for Adherence Monitoring to PrEP and ART and Establishing the Cutoff for a Point-of-Care Test. J Acquir Immune Defic Syndr. 2019 05 01; 81(1):72-77. PMID: 30664078.
      View in: PubMed
    11. Gandhi M, Spinelli MA, Mayer KH. Addressing the Sexually Transmitted Infection and HIV Syndemic. JAMA. 2019 04 09; 321(14):1356-1358. PMID: 30964514.
      View in: PubMed
    12. Spinelli MA, Glidden DV, Rodrigues WC, Wang G, Vincent M, Okochi H, Kuncze K, Mehrotra M, Defechereux P, Buchbinder SP, Grant RM, Gandhi M. Low tenofovir level in urine by a novel immunoassay is associated with seroconversion in a preexposure prophylaxis demonstration project. AIDS. 2019 04 01; 33(5):867-872. PMID: 30649051.
      View in: PubMed
    13. Spinelli MA, Scott HM, Vittinghoff E, Liu AY, Coleman K, Buchbinder SP. High Interest in Doxycycline for Sexually Transmitted Infection Postexposure Prophylaxis in a Multicity Survey of Men Who Have Sex With Men Using a Social Networking Application. Sex Transm Dis. 2019 04; 46(4):e32-e34. PMID: 30870327.
      View in: PubMed
    14. Spinelli MA, Scott HM, Vittinghoff E, Liu AY, Gonzalez R, Morehead-Gee A, Gandhi M, Buchbinder SP. Missed Visits Associated With Future Preexposure Prophylaxis (PrEP) Discontinuation Among PrEP Users in a Municipal Primary Care Health Network. Open Forum Infect Dis. 2019 Apr; 6(4):ofz101. PMID: 30949540.
      View in: PubMed
    15. Matthew A Spinelli, Hyman Scott, Eric Vittinghoff, Albert Y Liu, Kenneth Coleman, Monica Gandhi, Susan P Buchbinder. 2272. High Interest in Doxycycline for Sexually Transmitted Infection Post-Exposure Prophylaxis (Doxy-PEP) in a Multi-city Survey of Men Having Sex With Men (MSM) Using a Social-Networking App. Open Forum Infectious Diseases. 2018 Nov 26; 5(suppl_1):s672-s673.
      View in: Publisher Site
    16. Spinelli MA, Scott HM, Vittinghoff E, Liu AY, Morehead-Gee A, Gonzalez R, Gandhi M, Buchbinder SP. Brief Report: A Panel Management and Patient Navigation Intervention Is Associated With Earlier PrEP Initiation in a Safety-Net Primary Care Health System. J Acquir Immune Defic Syndr. 2018 11 01; 79(3):347-351. PMID: 30085955.
      View in: PubMed
    17. Gandhi M, Bacchetti P, Rodrigues WC, Spinelli M, Koss CA, Drain PK, Baeten JM, Mugo NR, Ngure K, Benet LZ, Okochi H, Wang G, Vincent M. Development and Validation of an Immunoassay for Tenofovir in Urine as a Real-Time Metric of Antiretroviral Adherence. EClinicalMedicine. 2018 Aug-Sep; 2-3:22-28. PMID: 30906930.
      View in: PubMed
    18. Spinelli MA, Scott HM, Vittinghoff E, Liu AY, Morehead-Gee A, Gonzalez R, Buchbinder SP. Provider Adherence to Pre-exposure Prophylaxis Monitoring Guidelines in a Large Primary Care Network. Open Forum Infect Dis. 2018 Jun; 5(6):ofy099. PMID: 29977959.
      View in: PubMed
    19. Spinelli MA, Frongillo EA, Sheira LA, Palar K, Tien PC, Wilson T, Merenstein D, Cohen M, Adedimeji A, Wentz E, Adimora AA, Metsch LR, Turan JM, Kushel MB, Weiser SD. Food Insecurity is Associated with Poor HIV Outcomes Among Women in the United States. AIDS Behav. 2017 Dec; 21(12):3473-3477. PMID: 29119474.
      View in: PubMed
    20. Spinelli MA, Ponath C, Tieu L, Hurstak EE, Guzman D, Kushel M. Factors associated with substance use in older homeless adults: Results from the HOPE HOME study. Subst Abus. 2017 Jan-Mar; 38(1):88-94. PMID: 27897965.
      View in: PubMed
    21. Papadopulos F, Spinelli M, Valente S, Foroni L, Orrico C, Alviano F, Pasquinelli G. Common tasks in microscopic and ultrastructural image analysis using ImageJ. Ultrastruct Pathol. 2007 Nov-Dec; 31(6):401-7. PMID: 18098058.
      View in: PubMed
    22. Chen P, Hübner W, Spinelli MA, Chen BK. Predominant mode of human immunodeficiency virus transfer between T cells is mediated by sustained Env-dependent neutralization-resistant virological synapses. J Virol. 2007 Nov; 81(22):12582-95. PMID: 17728240.
      View in: PubMed
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