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Bilateral Superficial Trigeminal Nerve Blocks are not more Effective than a Placebo in Abolishing Post-operative Headache in Pituitary Transsphenoidal Neurosurgery: A Prospective, Randomized, Double-blinded Clinical Trial. Rev Recent Clin Trials. 2023 Feb 27.
Srejic U, Litonius E, Gandhi S, Talke P, Maties O, Siegmueller C, Magsaysay A, Hasen D, Kunwar S, Seth R, Gibson L, Bickler P. PMID: 36843368.
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CTClinical Trials
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Electroencephalographic Arousal Patterns Under Dexmedetomidine Sedation. Anesth Analg. 2018 10; 127(4):951-959.
Sleigh JW, Vacas S, Flexman AM, Talke PO. PMID: 29933272.
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PubMed Mentions:
7 Fields:
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HumansCTClinical Trials
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Pharmacokinetics and pharmacodynamics of dexmedetomidine-induced vasoconstriction in healthy volunteers. Br J Clin Pharmacol. 2018 06; 84(6):1364-1372.
Talke P, Anderson BJ. PMID: 29495085; PMCID: PMC5980451.
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PubMed Mentions:
15 Fields:
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Humans
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The Effect of Tracheal Intubation-Induced Autonomic Response on Photoplethysmography. Anesthesiol Res Pract. 2017; 2017:7646541.
Talke P. PMID: 28469670; PMCID: PMC5392400.
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Republished: Society for Neuroscience in Anesthesiology and Critical Care expert consensus statement: Anesthetic management of endovascular treatment for acute ischemic stroke. Stroke. 2014 Aug; 45(8):e138-50.
Talke PO, Sharma D, Heyer EJ, Bergese SD, Blackham KA, Stevens RD. PMID: 25070964.
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22 Fields:
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Enzyme-inducing anticonvulsants increase plasma clearance of dexmedetomidine: a pharmacokinetic and pharmacodynamic study. Anesthesiology. 2014 May; 120(5):1118-25.
Flexman AM, Wong H, Riggs KW, Shih T, Garcia PA, Vacas S, Talke PO. PMID: 24487703.
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PubMed Mentions:
4 Fields:
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HumansCTClinical Trials
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Society for Neuroscience in Anesthesiology and Critical Care Expert consensus statement: anesthetic management of endovascular treatment for acute ischemic stroke*: endorsed by the Society of NeuroInterventional Surgery and the Neurocritical Care Society. J Neurosurg Anesthesiol. 2014 Apr; 26(2):95-108.
Talke PO, Sharma D, Heyer EJ, Bergese SD, Blackham KA, Stevens RD. PMID: 24594652.
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32 Fields:
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Humans
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The time when hypotension occurs may be important in the management of intraarterial thrombolysis for stroke. Anesthesiology. 2012 Sep; 117(3):683-4; author reply 684.
Gelb AW, Talke PO. PMID: 22914722.
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Humans
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Hemodynamic stability after intraarterial injection of verapamil for cerebral vasospasm. Anesth Analg. 2012 Jun; 114(6):1292-6.
Flexman AM, Ryerson CJ, Talke PO. PMID: 22451596.
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PubMed Mentions:
4 Fields:
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Humans
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Effect of pain on autonomic nervous system indices derived from photoplethysmography in healthy volunteers. Br J Anaesth. 2012 May; 108(5):838-44.
Hamunen K, Kontinen V, Hakala E, Talke P, Paloheimo M, Kalso E. PMID: 22369767.
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PubMed Mentions:
24 Fields:
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Humans
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The effects of sympathectomy on finger photoplethysmography and temperature measurements in healthy subjects. Anesth Analg. 2011 Jul; 113(1):78-83.
Talke P, Snapir A, Huiku M. PMID: 21519049.
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PubMed Mentions:
4 Fields:
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Humans
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Photoplethysmographic waveform: what do the numbers mean? Acta Anaesthesiol Scand. 2010 Aug; 54(7):900; author reply 900.
Talke P. PMID: 20649517.
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Humans
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Subthalamic nucleus deep brain stimulator placement using high-field interventional magnetic resonance imaging and a skull-mounted aiming device: technique and application accuracy. J Neurosurg. 2010 Mar; 112(3):479-90.
Starr PA, Martin AJ, Ostrem JL, Talke P, Levesque N, Larson PS. PMID: 19681683; PMCID: PMC2866526.
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PubMed Mentions:
50 Fields:
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Humans
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Recent advances in pulse oximetry. F1000 Med Rep. 2009 Aug 26; 1.
Cannesson M, Talke P. PMID: 20948714; PMCID: PMC2948314.
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6
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It's hot to be cool. Anesthesiology. 2009 Jul; 111(1):10-1.
Talke PO. PMID: 19512865.
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HumansAnimals
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Effects of nitric oxide synthase inhibition on dexmedetomidine-induced vasoconstriction in healthy human volunteers. Br J Anaesth. 2009 Jan; 102(1):38-46.
Snapir A, Talke P, Posti J, Huiku M, Kentala E, Scheinin M. PMID: 18987056.
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PubMed Mentions:
10 Fields:
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Humans
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Expecting the unexpected. Anesth Analg. 2008 Jun; 106(6):1605-6.
Talke PO, Maze M. PMID: 18499586.
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PubMed Mentions:
1 Fields:
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Humans
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Dexmedetomidine does not reduce epileptiform discharges in adults with epilepsy. J Neurosurg Anesthesiol. 2007 Jul; 19(3):195-9.
Talke P, Stapelfeldt C, Garcia P. PMID: 17592352.
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PubMed Mentions:
5 Fields:
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HumansCTClinical Trials
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Effect of peripheral vasoconstriction on pulse oximetry. J Clin Monit Comput. 2006 Oct; 20(5):305-9.
Talke P, Stapelfeldt C. PMID: 16841243.
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14 Fields:
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Humans
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Positive end-expiratory pressure ventilation increases extravascular lung water due to a decrease in lung lymph flow. Anaesth Intensive Care. 2006 Jun; 34(3):329-33.
Maybauer DM, Talke PO, Westphal M, Maybauer MO, Traber LD, Enkhbaatar P, Morita N, Traber DL. PMID: 16802485.
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PubMed Mentions:
8 Fields:
Translation:
Animals
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Placement of deep brain stimulator electrodes using real-time high-field interventional magnetic resonance imaging. Magn Reson Med. 2005 Nov; 54(5):1107-14.
Martin AJ, Larson PS, Ostrem JL, Keith Sootsman W, Talke P, Weber OM, Levesque N, Myers J, Starr PA. PMID: 16206144.
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PubMed Mentions:
23 Fields:
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HumansCTClinical Trials
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Intraoperative clonidine administration to neurosurgical patients. Anesth Analg. 2005 Sep; 101(3):923.
Talke PO, Lobo EP, Stapelfeldt C, Brown R. PMID: 16116018.
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Humans
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Alpha-2B adrenoceptor polymorphism and peripheral vasoconstriction. Pharmacogenet Genomics. 2005 May; 15(5):357-63.
Talke P, Stapelfeldt C, Lobo E, Brown R, Scheinin M, Snapir A. PMID: 15864138.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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Postcraniotomy pain remains a real headache! Eur J Anaesthesiol. 2005 May; 22(5):325-7.
Talke PO, Gelb AW. PMID: 15918377.
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PubMed Mentions:
11 Fields:
Translation:
Humans
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Effect of alpha2B-adrenoceptor polymorphism on peripheral vasoconstriction in healthy volunteers. Anesthesiology. 2005 Mar; 102(3):536-42.
Talke P, Stapelfeldt C, Lobo E, Brown R, Scheinin M, Snapir A. PMID: 15731590.
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PubMed Mentions:
11 Fields:
Translation:
Humans
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Intraoperative clonidine administration to neurosurgical patients. Anesth Analg. 2005 Jan; 100(1):226-232.
Stapelfeldt C, Lobo EP, Brown R, Talke PO. PMID: 15616082.
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PubMed Mentions:
4 Fields:
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HumansCTClinical Trials
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Intracranial vascular surgery. Curr Opin Anaesthesiol. 2004 Oct; 17(5):357-61.
Talke P. PMID: 17023890.
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Systemically administered alpha2-agonist-induced peripheral vasoconstriction in humans. Anesthesiology. 2003 Jul; 99(1):65-70.
Talke P, Lobo E, Brown R. PMID: 12826844.
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PubMed Mentions:
52 Fields:
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HumansCTClinical Trials
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Effects of intrathecally administered dexmedetomidine, MPV-2426 and tizanidine on EMG in rats. Acta Anaesthesiol Scand. 2003 Mar; 47(3):347-54.
Talke P, Xu M, Paloheimo M, Kalso E. PMID: 12648203.
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PubMed Mentions:
7 Fields:
Translation:
Animals
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Autonomic nervous system responses during sedative infusions of dexmedetomidine. Anesthesiology. 2002 Sep; 97(3):592-8.
Hogue CW, Talke P, Stein PK, Richardson C, Domitrovich PP, Sessler DI. PMID: 12218525.
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21 Fields:
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HumansCellsCTClinical Trials
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A comparison of three anesthetic techniques in patients undergoing craniotomy for supratentorial intracranial surgery. Anesth Analg. 2002 Aug; 95(2):430-5, table of contents.
Talke P, Caldwell JE, Brown R, Dodson B, Howley J, Richardson CA. PMID: 12145066.
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12 Fields:
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HumansCTClinical Trials
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Effect of dexmedetomidine, an alpha2-adrenoceptor agonist, on human pupillary reflexes during general anaesthesia. Br J Clin Pharmacol. 2001 Jan; 51(1):27-33.
Larson MD, Talke PO. PMID: 11167662; PMCID: PMC2014430.
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PubMed Mentions:
13 Fields:
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HumansCTClinical Trials
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The effects of clonidine on human digital vasculature. Anesth Analg. 2000 Oct; 91(4):793-7.
Talke PO, Caldwell JE, Richardson CA, Heier T. PMID: 11004028.
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PubMed Mentions:
2 Fields:
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HumansCTClinical Trials
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The effect of alpha(2) agonist-induced sedation and its reversal with an alpha(2) antagonist on organ blood flow in sheep. Anesth Analg. 2000 May; 90(5):1060-6.
Talke PO, Traber DL, Richardson CA, Harper DD, Traber LD. PMID: 10781453.
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PubMed Mentions:
2 Fields:
Translation:
Animals
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The hemodynamic and adrenergic effects of perioperative dexmedetomidine infusion after vascular surgery. Anesth Analg. 2000 Apr; 90(4):834-9.
Talke P, Chen R, Thomas B, Aggarwall A, Gottlieb A, Thorborg P, Heard S, Cheung A, Son SL, Kallio A. PMID: 10735784.
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PubMed Mentions:
70 Fields:
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HumansCTClinical Trials
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Sevoflurane increases lumbar cerebrospinal fluid pressure in normocapnic patients undergoing transsphenoidal hypophysectomy. Anesthesiology. 1999 Jul; 91(1):127-30.
Talke P, Caldwell JE, Richardson CA. PMID: 10422937.
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PubMed Mentions:
11 Fields:
Translation:
HumansCTClinical Trials
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Amount of air infused to patient increases as fluid flow rates decrease when using the Hotline HL-90 fluid warmer. J Clin Monit Comput. 1999 May; 15(3-4):149-52.
Woon S, Talke P. PMID: 12568165.
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PubMed Mentions:
1 Fields:
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Humans
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The effects of dexmedetomidine on neuromuscular blockade in human volunteers. Anesth Analg. 1999 Mar; 88(3):633-9.
Talke PO, Caldwell JE, Richardson CA, Kirkegaard-Nielsen H, Stafford M. PMID: 10072019.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Concept for easy fiberoptic intubation via a laryngeal airway mask. Anesth Analg. 1999 Jan; 88(1):228-9.
Talke PO, Nguyen H. PMID: 9895100.
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Humans
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Receptor-specific reversible sedation: beginning of new era of anesthesia? Anesthesiology. 1998 Sep; 89(3):560-1.
Talke P. PMID: 9743390.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Postoperative pharmacokinetics and sympatholytic effects of dexmedetomidine. Anesth Analg. 1997 Nov; 85(5):1136-42.
Talke P, Richardson CA, Scheinin M, Fisher DM. PMID: 9356115.
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PubMed Mentions:
64 Fields:
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HumansCTClinical Trials
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Dexmedetomidine does not alter the sweating threshold, but comparably and linearly decreases the vasoconstriction and shivering thresholds. Anesthesiology. 1997 Oct; 87(4):835-41.
Talke P, Tayefeh F, Sessler DI, Jeffrey R, Noursalehi M, Richardson C. PMID: 9357885.
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PubMed Mentions:
57 Fields:
Translation:
HumansCTClinical Trials
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The effect of clonidine on cerebral blood flow velocity, carbon dioxide cerebral vasoreactivity, and response to increased arterial pressure in human volunteers. Anesthesiology. 1997 Sep; 87(3):553-8.
Lee HW, Caldwell JE, Dodson B, Talke P, Howley J. PMID: 9316960.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Effect of dexmedetomidine on lumbar cerebrospinal fluid pressure in humans. Anesth Analg. 1997 Aug; 85(2):358-64.
Talke P, Tong C, Lee HW, Caldwell J, Eisenach JC, Richardson CA. PMID: 9249114.
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PubMed Mentions:
7 Fields:
Translation:
HumansCTClinical Trials
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Desflurane and isoflurane increase lumbar cerebrospinal fluid pressure in normocapnic patients undergoing transsphenoidal hypophysectomy. Anesthesiology. 1996 Nov; 85(5):999-1004.
Talke P, Caldwell J, Dodsont B, Richardson CA. PMID: 8916815.
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PubMed Mentions:
7 Fields:
Translation:
HumansCTClinical Trials
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Effects of dexmedetomidine on hypoxia-evoked glutamate release and glutamate receptor activity in hippocampal slices. Anesthesiology. 1996 Sep; 85(3):551-7.
Talke P, Bickler PE. PMID: 8853085.
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PubMed Mentions:
10 Fields:
Translation:
Animals
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Effects of perioperative dexmedetomidine infusion in patients undergoing vascular surgery. The Study of Perioperative Ischemia Research Group. Anesthesiology. 1995 Mar; 82(3):620-33.
Talke P, Li J, Jain U, Leung J, Drasner K, Hollenberg M, Mangano DT. PMID: 7879930.
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PubMed Mentions:
28 Fields:
Translation:
HumansCTClinical Trials
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Dose-response study of oral famotidine for reduction of gastric acidity and volume in outpatients and inpatients. Anesth Analg. 1993 Dec; 77(6):1143-8.
Talke PO, Solanki DR. PMID: 8250305.
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PubMed Mentions:
2 Fields:
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HumansCTClinical Trials
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Treatment of postoperative nausea and vomiting after outpatient surgery with the 5-HT3 antagonist ondansetron. Anesthesiology. 1993 Jan; 78(1):15-20.
Scuderi P, Wetchler B, Sung YF, Mingus M, DuPen S, Claybon L, Leslie J, Talke P, Apfelbaum J, Sharifi-Azad S, et al. PMID: 8424548.
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PubMed Mentions:
13 Fields:
Translation:
HumansCTClinical Trials
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Ondansetron in the treatment of postoperative nausea and vomiting in ambulatory outpatients: a dose-comparative, stratified, multicentre study. Eur J Anaesthesiol Suppl. 1992 Nov; 6:55-62.
Du Pen S, Scuderi P, Wetchler B, Sung YF, Mingus M, Clayborn L, Leslie J, Talke P, Apfelbaum J, Sharifi-Azad S, et al. PMID: 1425626.
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PubMed Mentions:
11 Fields:
Translation:
HumansCTClinical Trials
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Measurement of systolic blood pressure using pulse oximetry during helicopter flight. Crit Care Med. 1991 Jul; 19(7):934-7.
Talke PO. PMID: 2055082.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Monitoring patients during helicopter flight. J Clin Monit. 1990 Apr; 6(2):139-40.
Talke P, Nichols RJ, Traber DL. PMID: 2352001.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Does measurement of systolic blood pressure with a pulse oximeter correlate with conventional methods? J Clin Monit. 1990 Jan; 6(1):5-9.
Talke P, Nichols RJ, Traber DL. PMID: 2295896.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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Effects of allopurinol on smoke inhalation in the ovine model. J Appl Physiol (1985). 1990 Jan; 68(1):228-34.
Ahn SY, Sugi K, Talke P, Theissen JL, Linares HA, Traber LD, Herndon DN, Traber DL. PMID: 2312462.
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PubMed Mentions:
4 Fields:
Translation:
Animals
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A model of ovine endotoxemia characterized by an increased cardiac output. Circ Shock. 1985; 17(2):103-8.
Talke P, Dunn A, Lawlis L, Sziebert L, White A, Herndon D, Flynn JT, Traber D. PMID: 3902275.
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PubMed Mentions:
2 Fields:
Translation:
Animals
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Transcutaneous PO2 measurements in health and peripheral arterial occlusive disease. Surgery. 1982 Feb; 91(2):156-63.
Franzeck UK, Talke P, Bernstein EF, Golbranson FL, Fronek A. PMID: 7058493.
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PubMed Mentions:
15 Fields:
Translation:
Humans