Loading...

UCSF Coronavirus Response: UCSF is partnering with public agencies to address the rapidly evolving outbreak and protect our communities. The UCSF COVID-19 Resources Website provides guidance and information for our patients, faculty, staff, trainees and learners.

Pekka Talke, MD

Title(s)Professor, Anesthesia
SchoolSchool of Medicine
Phone415-476-8963
vCardDownload vCard

    Collapse ORNG Applications 
    Collapse Clinical Trials

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Sleigh JW, Vacas S, Flexman AM, Talke PO. Electroencephalographic Arousal Patterns Under Dexmedetomidine Sedation. Anesth Analg. 2018 10; 127(4):951-959. PMID: 29933272.
      View in: PubMed
    2. Talke P, Anderson BJ. Pharmacokinetics and pharmacodynamics of dexmedetomidine-induced vasoconstriction in healthy volunteers. Br J Clin Pharmacol. 2018 06; 84(6):1364-1372. PMID: 29495085.
      View in: PubMed
    3. Talke P. The Effect of Tracheal Intubation-Induced Autonomic Response on Photoplethysmography. Anesthesiol Res Pract. 2017; 2017:7646541. PMID: 28469670.
      View in: PubMed
    4. Talke PO, Sharma D, Heyer EJ, Bergese SD, Blackham KA, Stevens RD. Republished: Society for Neuroscience in Anesthesiology and Critical Care expert consensus statement: Anesthetic management of endovascular treatment for acute ischemic stroke. Stroke. 2014 Aug; 45(8):e138-50. PMID: 25070964.
      View in: PubMed
    5. Flexman AM, Wong H, Riggs KW, Shih T, Garcia PA, Vacas S, Talke PO. Enzyme-inducing anticonvulsants increase plasma clearance of dexmedetomidine: a pharmacokinetic and pharmacodynamic study. Anesthesiology. 2014 May; 120(5):1118-25. PMID: 24487703.
      View in: PubMed
    6. Talke PO, Sharma D, Heyer EJ, Bergese SD, Blackham KA, Stevens RD. Society for Neuroscience in Anesthesiology and Critical Care Expert consensus statement: anesthetic management of endovascular treatment for acute ischemic stroke*: endorsed by the Society of NeuroInterventional Surgery and the Neurocritical Care Society. J Neurosurg Anesthesiol. 2014 Apr; 26(2):95-108. PMID: 24594652.
      View in: PubMed
    7. Gelb AW, Talke PO. The time when hypotension occurs may be important in the management of intraarterial thrombolysis for stroke. Anesthesiology. 2012 Sep; 117(3):683-4; author reply 684. PMID: 22914722.
      View in: PubMed
    8. Flexman AM, Ryerson CJ, Talke PO. Hemodynamic stability after intraarterial injection of verapamil for cerebral vasospasm. Anesth Analg. 2012 Jun; 114(6):1292-6. PMID: 22451596.
      View in: PubMed
    9. Hamunen K, Kontinen V, Hakala E, Talke P, Paloheimo M, Kalso E. Effect of pain on autonomic nervous system indices derived from photoplethysmography in healthy volunteers. Br J Anaesth. 2012 May; 108(5):838-44. PMID: 22369767.
      View in: PubMed
    10. Talke P, Snapir A, Huiku M. The effects of sympathectomy on finger photoplethysmography and temperature measurements in healthy subjects. Anesth Analg. 2011 Jul; 113(1):78-83. PMID: 21519049.
      View in: PubMed
    11. Talke P. Photoplethysmographic waveform: what do the numbers mean? Acta Anaesthesiol Scand. 2010 Aug; 54(7):900; author reply 900. PMID: 20649517.
      View in: PubMed
    12. Starr PA, Martin AJ, Ostrem JL, Talke P, Levesque N, Larson PS. Subthalamic nucleus deep brain stimulator placement using high-field interventional magnetic resonance imaging and a skull-mounted aiming device: technique and application accuracy. J Neurosurg. 2010 Mar; 112(3):479-90. PMID: 19681683.
      View in: PubMed
    13. Cannesson M, Talke P. Recent advances in pulse oximetry. F1000 Med Rep. 2009 Aug 26; 1. PMID: 20948714.
      View in: PubMed
    14. Talke PO. It's hot to be cool. Anesthesiology. 2009 Jul; 111(1):10-1. PMID: 19512865.
      View in: PubMed
    15. Snapir A, Talke P, Posti J, Huiku M, Kentala E, Scheinin M. Effects of nitric oxide synthase inhibition on dexmedetomidine-induced vasoconstriction in healthy human volunteers. Br J Anaesth. 2009 Jan; 102(1):38-46. PMID: 18987056.
      View in: PubMed
    16. Talke PO, Maze M. Expecting the unexpected. Anesth Analg. 2008 Jun; 106(6):1605-6. PMID: 18499586.
      View in: PubMed
    17. Talke P, Stapelfeldt C, Garcia P. Dexmedetomidine does not reduce epileptiform discharges in adults with epilepsy. J Neurosurg Anesthesiol. 2007 Jul; 19(3):195-9. PMID: 17592352.
      View in: PubMed
    18. Talke P, Stapelfeldt C. Effect of peripheral vasoconstriction on pulse oximetry. J Clin Monit Comput. 2006 Oct; 20(5):305-9. PMID: 16841243.
      View in: PubMed
    19. Maybauer DM, Talke PO, Westphal M, Maybauer MO, Traber LD, Enkhbaatar P, Morita N, Traber DL. Positive end-expiratory pressure ventilation increases extravascular lung water due to a decrease in lung lymph flow. Anaesth Intensive Care. 2006 Jun; 34(3):329-33. PMID: 16802485.
      View in: PubMed
    20. Martin AJ, Larson PS, Ostrem JL, Keith Sootsman W, Talke P, Weber OM, Levesque N, Myers J, Starr PA. Placement of deep brain stimulator electrodes using real-time high-field interventional magnetic resonance imaging. Magn Reson Med. 2005 Nov; 54(5):1107-14. PMID: 16206144.
      View in: PubMed
    21. Talke P, Stapelfeldt C, Lobo E, Brown R, Scheinin M, Snapir A. Alpha-2B adrenoceptor polymorphism and peripheral vasoconstriction. Pharmacogenet Genomics. 2005 May; 15(5):357-63. PMID: 15864138.
      View in: PubMed
    22. Talke PO, Gelb AW. Postcraniotomy pain remains a real headache! Eur J Anaesthesiol. 2005 May; 22(5):325-7. PMID: 15918377.
      View in: PubMed
    23. Talke P, Stapelfeldt C, Lobo E, Brown R, Scheinin M, Snapir A. Effect of alpha2B-adrenoceptor polymorphism on peripheral vasoconstriction in healthy volunteers. Anesthesiology. 2005 Mar; 102(3):536-42. PMID: 15731590.
      View in: PubMed
    24. Stapelfeldt C, Lobo EP, Brown R, Talke PO. Intraoperative clonidine administration to neurosurgical patients. Anesth Analg. 2005 Jan; 100(1):226-32. PMID: 15616082.
      View in: PubMed
    25. Talke P. Intracranial vascular surgery. Curr Opin Anaesthesiol. 2004 Oct; 17(5):357-61. PMID: 17023890.
      View in: PubMed
    26. Talke P, Lobo E, Brown R. Systemically administered alpha2-agonist-induced peripheral vasoconstriction in humans. Anesthesiology. 2003 Jul; 99(1):65-70. PMID: 12826844.
      View in: PubMed
    27. Talke P, Xu M, Paloheimo M, Kalso E. Effects of intrathecally administered dexmedetomidine, MPV-2426 and tizanidine on EMG in rats. Acta Anaesthesiol Scand. 2003 Mar; 47(3):347-54. PMID: 12648203.
      View in: PubMed
    28. Hogue CW, Talke P, Stein PK, Richardson C, Domitrovich PP, Sessler DI. Autonomic nervous system responses during sedative infusions of dexmedetomidine. Anesthesiology. 2002 Sep; 97(3):592-8. PMID: 12218525.
      View in: PubMed
    29. Talke P, Caldwell JE, Brown R, Dodson B, Howley J, Richardson CA. A comparison of three anesthetic techniques in patients undergoing craniotomy for supratentorial intracranial surgery. Anesth Analg. 2002 Aug; 95(2):430-5, table of contents. PMID: 12145066.
      View in: PubMed
    30. Talke PO, Lobo EP, Brown R, Richardson CA. Clonidine-induced vasoconstriction in awake volunteers. Anesth Analg. 2001 Aug; 93(2):271-6, 1st contents page. PMID: 11473842.
      View in: PubMed
    31. Gao DW, Talke PO, Dae MW. Effects of reduced sympathetic activity on myocardial metaiodobenzylguanidine (MIBG) washout. J Auton Pharmacol. 2001 Jun; 21(3):159-64. PMID: 11844024.
      View in: PubMed
    32. Larson MD, Talke PO. Effect of dexmedetomidine, an alpha2-adrenoceptor agonist, on human pupillary reflexes during general anaesthesia. Br J Clin Pharmacol. 2001 Jan; 51(1):27-33. PMID: 11167662.
      View in: PubMed
    33. Talke PO, Caldwell JE, Richardson CA, Heier T. The effects of clonidine on human digital vasculature. Anesth Analg. 2000 Oct; 91(4):793-7. PMID: 11004028.
      View in: PubMed
    34. Talke PO, Traber DL, Richardson CA, Harper DD, Traber LD. The effect of alpha(2) agonist-induced sedation and its reversal with an alpha(2) antagonist on organ blood flow in sheep. Anesth Analg. 2000 May; 90(5):1060-6. PMID: 10781453.
      View in: PubMed
    35. Talke P, Chen R, Thomas B, Aggarwall A, Gottlieb A, Thorborg P, Heard S, Cheung A, Son SL, Kallio A. The hemodynamic and adrenergic effects of perioperative dexmedetomidine infusion after vascular surgery. Anesth Analg. 2000 Apr; 90(4):834-9. PMID: 10735784.
      View in: PubMed
    36. Talke P, Caldwell JE, Richardson CA. Sevoflurane increases lumbar cerebrospinal fluid pressure in normocapnic patients undergoing transsphenoidal hypophysectomy. Anesthesiology. 1999 Jul; 91(1):127-30. PMID: 10422937.
      View in: PubMed
    37. Woon S, Talke P. Amount of air infused to patient increases as fluid flow rates decrease when using the Hotline HL-90 fluid warmer. J Clin Monit Comput. 1999 May; 15(3-4):149-52. PMID: 12568165.
      View in: PubMed
    38. Talke PO, Caldwell JE, Richardson CA, Kirkegaard-Nielsen H, Stafford M. The effects of dexmedetomidine on neuromuscular blockade in human volunteers. Anesth Analg. 1999 Mar; 88(3):633-9. PMID: 10072019.
      View in: PubMed
    39. Talke PO, Nguyen H. Concept for easy fiberoptic intubation via a laryngeal airway mask. Anesth Analg. 1999 Jan; 88(1):228-9. PMID: 9895100.
      View in: PubMed
    40. Talke P. Receptor-specific reversible sedation: beginning of new era of anesthesia? Anesthesiology. 1998 Sep; 89(3):560-1. PMID: 9743390.
      View in: PubMed
    41. Talke P, Richardson CA, Scheinin M, Fisher DM. Postoperative pharmacokinetics and sympatholytic effects of dexmedetomidine. Anesth Analg. 1997 Nov; 85(5):1136-42. PMID: 9356115.
      View in: PubMed
    42. Talke P, Tayefeh F, Sessler DI, Jeffrey R, Noursalehi M, Richardson C. Dexmedetomidine does not alter the sweating threshold, but comparably and linearly decreases the vasoconstriction and shivering thresholds. Anesthesiology. 1997 Oct; 87(4):835-41. PMID: 9357885.
      View in: PubMed
    43. Lee HW, Caldwell JE, Dodson B, Talke P, Howley J. The effect of clonidine on cerebral blood flow velocity, carbon dioxide cerebral vasoreactivity, and response to increased arterial pressure in human volunteers. Anesthesiology. 1997 Sep; 87(3):553-8. PMID: 9316960.
      View in: PubMed
    44. Talke P, Tong C, Lee HW, Caldwell J, Eisenach JC, Richardson CA. Effect of dexmedetomidine on lumbar cerebrospinal fluid pressure in humans. Anesth Analg. 1997 Aug; 85(2):358-64. PMID: 9249114.
      View in: PubMed
    45. Talke P, Caldwell J, Dodsont B, Richardson CA. Desflurane and isoflurane increase lumbar cerebrospinal fluid pressure in normocapnic patients undergoing transsphenoidal hypophysectomy. Anesthesiology. 1996 Nov; 85(5):999-1004. PMID: 8916815.
      View in: PubMed
    46. Talke P, Bickler PE. Effects of dexmedetomidine on hypoxia-evoked glutamate release and glutamate receptor activity in hippocampal slices. Anesthesiology. 1996 Sep; 85(3):551-7. PMID: 8853085.
      View in: PubMed
    47. Talke P, Li J, Jain U, Leung J, Drasner K, Hollenberg M, Mangano DT. Effects of perioperative dexmedetomidine infusion in patients undergoing vascular surgery. The Study of Perioperative Ischemia Research Group. Anesthesiology. 1995 Mar; 82(3):620-33. PMID: 7879930.
      View in: PubMed
    48. Talke PO, Solanki DR. Dose-response study of oral famotidine for reduction of gastric acidity and volume in outpatients and inpatients. Anesth Analg. 1993 Dec; 77(6):1143-8. PMID: 8250305.
      View in: PubMed
    49. Scuderi P, Wetchler B, Sung YF, Mingus M, DuPen S, Claybon L, Leslie J, Talke P, Apfelbaum J, Sharifi-Azad S. Treatment of postoperative nausea and vomiting after outpatient surgery with the 5-HT3 antagonist ondansetron. Anesthesiology. 1993 Jan; 78(1):15-20. PMID: 8424548.
      View in: PubMed
    50. Du Pen S, Scuderi P, Wetchler B, Sung YF, Mingus M, Clayborn L, Leslie J, Talke P, Apfelbaum J, Sharifi-Azad S. Ondansetron in the treatment of postoperative nausea and vomiting in ambulatory outpatients: a dose-comparative, stratified, multicentre study. Eur J Anaesthesiol Suppl. 1992 Nov; 6:55-62. PMID: 1425626.
      View in: PubMed
    51. Talke PO. Measurement of systolic blood pressure using pulse oximetry during helicopter flight. Crit Care Med. 1991 Jul; 19(7):934-7. PMID: 2055082.
      View in: PubMed
    52. Talke P, Nichols RJ, Traber DL. Monitoring patients during helicopter flight. J Clin Monit. 1990 Apr; 6(2):139-40. PMID: 2352001.
      View in: PubMed
    53. Ahn SY, Sugi K, Talke P, Theissen JL, Linares HA, Traber LD, Herndon DN, Traber DL. Effects of allopurinol on smoke inhalation in the ovine model. J Appl Physiol (1985). 1990 Jan; 68(1):228-34. PMID: 2312462.
      View in: PubMed
    54. Talke P, Nichols RJ, Traber DL. Does measurement of systolic blood pressure with a pulse oximeter correlate with conventional methods? J Clin Monit. 1990 Jan; 6(1):5-9. PMID: 2295896.
      View in: PubMed
    55. Talke P, Dunn A, Lawlis L, Sziebert L, White A, Herndon D, Flynn JT, Traber D. A model of ovine endotoxemia characterized by an increased cardiac output. Circ Shock. 1985; 17(2):103-8. PMID: 3902275.
      View in: PubMed
    56. Franzeck UK, Talke P, Bernstein EF, Golbranson FL, Fronek A. Transcutaneous PO2 measurements in health and peripheral arterial occlusive disease. Surgery. 1982 Feb; 91(2):156-63. PMID: 7058493.
      View in: PubMed