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Michael Dae, MD

TitleProfessor Emeritus
SchoolUCSF School of Medicine
DepartmentRadiology
Address185 Berry Street
San Francisco CA 94143
Phone415-353-9473
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoClinical Fellowship Radiology
    University of California, San Francisco Residency School of Medicine
    Duke UniversityM.D.1976School of Medicine
    Collapse Awards and Honors
    American College of Cardiology2003Fellow Award
    Best Doctors in America2003Cardiovascular Diseases, Nuclear Medicine
    NIH1988  - 1993First Award
    niversity of California, San Francisco1988Pre-Tenure Award
    University of California, San Francisco1987Academic Senate Faculty Development Award
    PHS1978Research Training Grant

    Collapse Overview 
    Collapse Overview
    Michael Dae, MD, is a Professor in Residence in Nuclear Medicine Section at the University of California, San Francisco. Dr. Dae obtained his medical degree in Medicine from Duke University in Durham, North Carolina in 1976, and completed his residency in Pediatrics at the Children’s Hospital in Boston, Massachusetts in 1978, followed by a fellowship in Pediatric Cardiology and Nuclear Cardiology from UCSF. Currently, he leads an initiative to increase clinical utilization of cardiac positron emission tomographic imaging (PET) for patients to provide better diagnostic imaging with less radiation exposure, and greater patient experience.

    As a research focus, Dr. Dae and his colleagues have developed extensive experience with radionuclide assessment of myocardial sympathetic innervation. They evaluate the ability of MIBG to map sympathetic innervation in various experimental models of cardiac disease, and have characterized the physiologic and electro physiologic consequences of abdominal uptake and distribution of the tracer. Also, Dr. Dae and his colleagues have extensive experience in the pre-clinical and clinical assessment of new medical devices in cardiovascular medicine, ranging from assessment of prototypes to the completion of GLP studies for FDA submissions.

    Dr. Dae has published and written 93 articles, 27 book chapters, and 6 significant publications. He is responsible for conceiving studies, assisting with trail designs, supervising performances, and designing imaging aspects of the experiments.

    Expertise:
    Nuclear Medicine

    Specialty:
    Nuclear cardiology

    Professional Interests:
    Development of a noninvasive approach to treat acute and chronic kidney disease

    Education and Training:
    • Medical School: Duke University, Durham, North Carolina - Medicine
    • Internship: Children’s Hospital, Boston, Massachusetts - Pediatrics
    • Residency: Children’s Hospital, Boston, Massachusetts - Pediatrics
    • Residency: University of California, San Francisco - Nuclear Medicine, Chief Resident
    • Fellowship: University of California, San Francisco - Pediatric Cardiology
    • Fellowship: University of California, San Francisco - Nuclear Cardiology
    • Master of Business Administration: University of San Francisco - Business
    • Diplomate, National Board of Medical Examiners
    • California License
    • American Board of Pediatrics
    • American Board of Nuclear Medicine
    • Certified - Advanced Cardiac Life Support
    • Certified - Basic Life Support
    • Level 2 Certification for Competency in Cardiac CT
    • Certificate of Proficiency - PET/CT - American College of Radiology
    • Certified - Advanced Cardiac Life Support


    Collapse Research 
    Collapse Research Activities and Funding
    NERVE AND REPOLARIZATION IMAGING IN SUDDEN CARDIAC DEATH
    NIH/NHLBI R01HL064961Jun 1, 2000 - May 31, 2005
    Role: Principal Investigator
    RADIONUCLIDE IMAGING USING I 125 MIBG IN NEWBORN HEARTS
    NIH/NHLBI R01HL055234Mar 1, 1996 - Feb 29, 2000
    Role: Principal Investigator
    NONINVASIVE ASSESSMENT OF CARDIAC ADRENERGIC INNERVATION
    NIH/NHLBI R29HL038105Apr 1, 1988 - Mar 31, 1994
    Role: Principal Investigator
    MYOCARDIAL ISCHEMIA
    NIH P01HL025847Jun 1, 1980 - Dec 31, 1999
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Mateos-Pérez JM, Desco M, Dae M, García-Villalba C, Cussó L, Vaquero JJ. Automatic TAC extraction from dynamic cardiac PET imaging using iterative correlation from a population template. Comput Methods Programs Biomed. 2013 Aug; 111(2):308-14. PMID: 23693137.
      View in: PubMed
    2. Vaquero JJ, Gao DW, García-Villaba C, Bacharach S, Vanbrocklin H, Fang Q, Desco M, Lee R, Dae M. Approach to assessing myocardial perfusion in rats using static [13N]-ammonia images and a small-animal PET. Mol Imaging Biol. 2012 Oct; 14(5):541-5. PMID: 22278106.
      View in: PubMed
    3. Sayre GA, Bacharach SL, Dae M, Seo Y. Combining dynamic and ECG-gated 8²Rb-PET for practical implementation in the clinic. Nucl Med Commun. 2012 Jan; 33(1):4-13. PMID: 21934541; PMCID: PMC3227790.
    4. Mihardja SS, Gao D, Sievers RE, Fang Q, Feng J, Wang J, Vanbrocklin HF, Larrick JW, Huang M, Dae M, Lee RJ. Targeted in vivo extracellular matrix formation promotes neovascularization in a rodent model of myocardial infarction. PLoS One. 2010 Apr 28; 5(4):e10384. PMID: 20442783; PMCID: PMC2860995.
    5. Nikolic SD, Khairkhahan A, Ryu M, Champsaur G, Breznock E, Dae M. Percutaneous implantation of an intraventricular device for the treatment of heart failure: experimental results and proof of concept. J Card Fail. 2009 Nov; 15(9):790-7. PMID: 19879466.
      View in: PubMed
    6. del Romeral LM, Stillson C, Lesh M, Dae M, Botvinick E. The relationship of myocardial contraction and electrical excitation--the correlation between scintigraphic phase image analysis and electrophysiologic mapping. J Nucl Cardiol. 2009 Sep-Oct; 16(5):792-800. PMID: 19636652; PMCID: PMC2746295.
    7. Botvinick E, Davis J, Dae M, O'Connell J, Schechtmann N, Abbott J, Morady F, Lanzer P, Iskikian J, Scheinman M. Localization of ventricular tachycardia exit site and subsequent contraction sequence and functional effects with bedside radionuclide angiography. JACC Cardiovasc Imaging. 2008 Sep; 1(5):605-13. PMID: 19356489.
      View in: PubMed
    8. Dae M. Pediatric nuclear cardiology. Semin Nucl Med. 2007 Sep; 37(5):382-90. PMID: 17707243.
      View in: PubMed
    9. Seo Y, Gao DW, Hasegawa BH, Dae M, Franc BL. Rodent brain imaging with SPECT/CT. Med Phys. 2007 Apr; 34(4):1217-20. PMID: 17500453.
      View in: PubMed
    10. Banki N, Kopelnik A, Tung P, Lawton MT, Gress D, Drew B, Dae M, Foster E, Parmley W, Zaroff J. Prospective analysis of prevalence, distribution, and rate of recovery of left ventricular systolic dysfunction in patients with subarachnoid hemorrhage. J Neurosurg. 2006 Jul; 105(1):15-20. PMID: 16871878.
      View in: PubMed
    11. Sharkey H, Nikolic S, Khairkhahan A, Dae M. Left ventricular apex occluder. Description of a Ventricular Partitioning Device. EuroIntervention. 2006 May; 2(1):125-7. PMID: 19755248.
      View in: PubMed
    12. Banki NM, Kopelnik A, Dae M, Miss J, Tung P, Lawton MT, Drew BJ, Foster E, Smith W, Parmley WW, Zaroff JG. Acute neurocardiogenic injury after subarachnoid hemorrhage. Circulation. 2005 Nov 22; 112(21):3314-9. PMID: 16286583.
      View in: PubMed
    13. Khush K, Kopelnik A, Tung P, Banki N, Dae M, Lawton M, Smith W, Drew B, Foster E, Zaroff J. Age and aneurysm position predict patterns of left ventricular dysfunction after subarachnoid hemorrhage. J Am Soc Echocardiogr. 2005 Feb; 18(2):168-74. PMID: 15682055.
      View in: PubMed
    14. Frelinger AL, Furman MI, Barnard MR, Krueger LA, Dae M, Michelson AD. Combined effects of mild hypothermia and glycoprotein IIb/IIIa antagonists on platelet-platelet and leukocyte-platelet aggregation. Am J Cardiol. 2003 Nov 01; 92(9):1099-101. PMID: 14583364.
      View in: PubMed
    15. Hale SL, Dae M, Kloner RA. Hypothermia during reperfusion limits 'no-reflow' injury in a rabbit model of acute myocardial infarction. Cardiovasc Res. 2003 Sep 01; 59(3):715-22. PMID: 14499873.
      View in: PubMed
    16. Wu MC, Gao DW, Sievers RE, Lee RJ, Hasegawa BH, Dae M. Pinhole single-photon emission computed tomography for myocardial perfusion imaging of mice. J Am Coll Cardiol. 2003 Aug 06; 42(3):576-82. PMID: 12906991.
      View in: PubMed
    17. Dae M, Gao DW, Ursell PC, Stillson CA, Sessler DI. Safety and efficacy of endovascular cooling and rewarming for induction and reversal of hypothermia in human-sized pigs. Stroke. 2003 Mar; 34(3):734-8. PMID: 12624300.
      View in: PubMed
    18. Dixon SR, Whitbourn RJ, Dae M, Grube E, Sherman W, Schaer GL, Jenkins JS, Baim DS, Gibbons RJ, Kuntz RE, Popma JJ, Nguyen TT, O'Neill WW. Induction of mild systemic hypothermia with endovascular cooling during primary percutaneous coronary intervention for acute myocardial infarction. J Am Coll Cardiol. 2002 Dec 04; 40(11):1928-34. PMID: 12475451.
      View in: PubMed
    19. Wu MC, Hasegawa BH, Dae M. Performance evaluation of a pinhole SPECT system for myocardial perfusion imaging of mice. Med Phys. 2002 Dec; 29(12):2830-9. PMID: 12512717.
      View in: PubMed
    20. Dae M, Gao DW, Sessler DI, Chair K, Stillson CA. Effect of endovascular cooling on myocardial temperature, infarct size, and cardiac output in human-sized pigs. Am J Physiol Heart Circ Physiol. 2002 May; 282(5):H1584-91. PMID: 11959619.
      View in: PubMed
    21. Johnson LL, Thambar S, Donahay T, Dae M, Williams DO. Effect of endomyocardial laser channels on regional innervation shown with (125)I-MIBG and autoradiography. J Nucl Med. 2002 Apr; 43(4):551-5. PMID: 11937601.
      View in: PubMed
    22. Mokhtarani M, Mahgoub AN, Morioka N, Doufas AG, Dae M, Shaughnessy TE, Bjorksten AR, Sessler DI. Buspirone and meperidine synergistically reduce the shivering threshold. Anesth Analg. 2001 Nov; 93(5):1233-9. PMID: 11682404.
      View in: PubMed
    23. Gao DW, Talke PO, Dae M. Effects of reduced sympathetic activity on myocardial metaiodobenzylguanidine (MIBG) washout. J Auton Pharmacol. 2001 Jun; 21(3):159-64. PMID: 11844024.
      View in: PubMed
    24. Da Silva AJ, Tang HR, Wong KH, Wu MC, Dae M, Hasegawa BH. Absolute quantification of regional myocardial uptake of 99mTc-sestamibi with SPECT: experimental validation in a porcine model. J Nucl Med. 2001 May; 42(5):772-9. PMID: 11337575.
      View in: PubMed
    25. Arheden H, Saeed M, Higgins CB, Gao DW, Ursell PC, Bremerich J, Wyttenbach R, Dae M, Wendland MF. Reperfused rat myocardium subjected to various durations of ischemia: estimation of the distribution volume of contrast material with echo-planar MR imaging. Radiology. 2000 May; 215(2):520-8. PMID: 10796935.
      View in: PubMed
    26. Redberg RF, Nishino M, McElhinney DB, Dae M, Botvinick EH. Long-term estrogen replacement therapy is associated with improved exercise capacity in postmenopausal women without known coronary artery disease. Am Heart J. 2000 Apr; 139(4):739-44. PMID: 10740161.
      View in: PubMed
    27. Yoshioka K, Gao DW, Chin M, Stillson C, Penades E, Lesh M, O'Connell W, Dae M. Heterogeneous sympathetic innervation influences local myocardial repolarization in normally perfused rabbit hearts. Circulation. 2000 Mar 07; 101(9):1060-6. PMID: 10704175.
      View in: PubMed
    28. Oka RK, De Marco T, Haskell WL, Botvinick E, Dae M, Bolen K, Chatterjee K. Impact of a home-based walking and resistance training program on quality of life in patients with heart failure. Am J Cardiol. 2000 Feb 01; 85(3):365-9. PMID: 11078308.
      View in: PubMed
    29. Arheden H, Saeed M, Higgins CB, Gao DW, Bremerich J, Wyttenbach R, Dae M, Wendland MF. Measurement of the distribution volume of gadopentetate dimeglumine at echo-planar MR imaging to quantify myocardial infarction: comparison with 99mTc-DTPA autoradiography in rats. Radiology. 1999 Jun; 211(3):698-708. PMID: 10352594.
      View in: PubMed
    30. Bremerich J, Wendland MF, Arheden H, Wyttenbach R, Gao DW, Huberty JP, Dae M, Higgins CB, Saeed M. Microvascular injury in reperfused infarcted myocardium: noninvasive assessment with contrast-enhanced echoplanar magnetic resonance imaging. J Am Coll Cardiol. 1998 Sep; 32(3):787-93. PMID: 9741528.
      View in: PubMed
    31. Botvinick EH, O'Connell JW, Kadkade PP, Glickman SL, Dae M, Cohen TJ, Abbott J, Krishnan R. Potential added value of three-dimensional reconstruction and display of single photon emission computed tomographic gated blood pool images. J Nucl Cardiol. 1998 May-Jun; 5(3):245-55. PMID: 9669579.
      View in: PubMed
    32. Bobba K, Botvinick EH, Sciammarella MG, Starsken NF, Zhu YY, Lapidus A, Dae M. Is there any advantage to the acquisition of 24-hour thallium images, in the presence of persistent perfusion defects at 4 h after reinjection? Eur J Nucl Med. 1998 May; 25(5):509-14. PMID: 9575247.
      View in: PubMed
    33. Wendland MF, Saeed M, Arheden H, Gao DW, Canet E, Bremerich J, Dae M, Higgins CB. Toward necrotic cell fraction measurement by contrast-enhanced MRI of reperfused ischemically injured myocardium. Acad Radiol. 1998 Apr; 5 Suppl 1:S42-4; discussion S45-6. PMID: 9561040.
      View in: PubMed
    34. DePuey EG, Port S, Wackers FJ, Rozanski A, Botvinick EH, Dae M, Tamaki N. Nonperfusion applications in nuclear cardiology: report of a task force of the American Society of Nuclear Cardiology. J Nucl Cardiol. 1998 Mar-Apr; 5(2):218-31. PMID: 9588675.
      View in: PubMed
    35. Kalki K, Blankespoor SC, Brown JK, Hasegawa BH, Dae M, Chin M, Stillson C. Myocardial perfusion imaging with a combined x-ray CT and SPECT system. J Nucl Med. 1997 Oct; 38(10):1535-40. PMID: 9379188.
      View in: PubMed
    36. Segall GM, Stepp C, Kadkade PP, Dae M, Botvinick EH. Fast acquisition of myocardial SPECT images with Tc-99m sestamibi for the diagnosis of coronary artery disease. J Nucl Cardiol. 1997 Sep-Oct; 4(5):358-63. PMID: 9362011.
      View in: PubMed
    37. Dae M, Lee RJ, Ursell PC, Chin MC, Stillson CA, Moise NS. Heterogeneous sympathetic innervation in German shepherd dogs with inherited ventricular arrhythmia and sudden cardiac death. Circulation. 1997 Aug 19; 96(4):1337-42. PMID: 9286967.
      View in: PubMed
    38. Ellis WS, Eisenberg SJ, Auslander DM, Dae M, Zakhor A, Lesh MD. Deconvolution: a novel signal processing approach for determining activation time from fractionated electrograms and detecting infarcted tissue. Circulation. 1996 Nov 15; 94(10):2633-40. PMID: 8921811.
      View in: PubMed
    39. Dae M, O'Connell JW, Botvinick EH, Chin MC. Acute and chronic effects of transient myocardial ischemia on sympathetic nerve activity, density, and norepinephrine content. Cardiovasc Res. 1995 Aug; 30(2):270-80. PMID: 7585815.
      View in: PubMed
    40. Segall GM, Atwood JE, Botvinick EH, Dae M, Lucas JR. Variability of normal coronary anatomy: implications for the interpretation of thallium-SPECT myocardial perfusion images in single-vessel disease. J Nucl Med. 1995 Jun; 36(6):944-51. PMID: 7769450.
      View in: PubMed
    41. Lurie KG, Dae M, Dutton J, Velazquez-Rocha SJ, O'Connell JW. Metaiodobenzylguanidine as an index of atrioventricular nodal adrenergic activity. J Nucl Med. 1995 Jun; 36(6):1096-101. PMID: 7769434.
      View in: PubMed
    42. De Marco T, Dae M, Yuen-Green MS, Kumar S, Sudhir K, Keith F, Amidon TM, Rifkin C, Klinski C, Lau D. Iodine-123 metaiodobenzylguanidine scintigraphic assessment of the transplanted human heart: evidence for late reinnervation. J Am Coll Cardiol. 1995 Mar 15; 25(4):927-31. PMID: 7884099.
      View in: PubMed
    43. Dae M. Scintigraphy of myocardial innervation with metaiodobenzylguanidine (MIBG): is there a clinical application? J Nucl Cardiol. 1995 Mar-Apr; 2(2 Pt 1):151-4. PMID: 9420780.
      View in: PubMed
    44. Foster E, O'Kelly B, LaPidus A, Sandler D, Tucker K, Dae M, Schiller NB, Botvinick EH. Segmental analysis of resting echocardiographic function and stress scintigraphic perfusion: implications for myocardial viability. Am Heart J. 1995 Jan; 129(1):7-14. PMID: 7817927.
      View in: PubMed
    45. Dae M. Myocardial perfusion after repair of transposition: is it worth the switch? J Am Coll Cardiol. 1994 Sep; 24(3):778-9. PMID: 8077552.
      View in: PubMed
    46. Lee MA, Dae M, Langberg JJ, Griffin JC, Chin MC, Finkbeiner WE, O'Connell JW, Botvinick E, Scheinman MM, Rosenqvist M. Effects of long-term right ventricular apical pacing on left ventricular perfusion, innervation, function and histology. J Am Coll Cardiol. 1994 Jul; 24(1):225-32. PMID: 8006270.
      View in: PubMed
    47. Krishnan R, Lu J, Dae M, Botvinick EH. Does myocardial perfusion scintigraphy demonstrate clinical usefulness in patients with markedly positive exercise tests? An assessment of the method in a high-risk subset. Am Heart J. 1994 Apr; 127(4 Pt 1):804-16. PMID: 8154418.
      View in: PubMed
    48. Dae M. Imaging of myocardial sympathetic innervation with metaiodobenzylguanidine. J Nucl Cardiol. 1994 Mar-Apr; 1(2 Pt 2):S23-30. PMID: 9420694.
      View in: PubMed
    49. Dae M, Lesh MD. Radionuclide imaging tools for understanding arrhythmia mechanisms. J Electrocardiol. 1994; 27 Suppl:121-6. PMID: 7884347.
      View in: PubMed
    50. Wolfe CL, O'Connell JW, Sievers RE, Cobb C, Dae M, Botvinick E. Assessment of perfused left ventricular mass in normal, ischemic, and reperfused myocardium by means of single-photon emission computed tomography of technetium-99m isonitrile. Am Heart J. 1993 Dec; 126(6):1275-86. PMID: 8249782.
      View in: PubMed
    51. Newman D, Munoz L, Chin M, Franz M, Herre J, Scheinman MM, Botvinick E, Dae M. Effects of canine myocardial infarction on sympathetic efferent neuronal function: scintigraphic and electrophysiologic correlates. Am Heart J. 1993 Nov; 126(5):1106-12. PMID: 8237752.
      View in: PubMed
    52. Yu KK, Saeed M, Wendland MF, Dae M, Velasquez-Rocha S, Derugin N, Higgins CB. Comparison of T1-enhancing and magnetic susceptibility magnetic resonance contrast agents for demarcation of the jeopardy area in experimental myocardial infarction. Invest Radiol. 1993 Nov; 28(11):1015-23. PMID: 7506243.
      View in: PubMed
    53. Botvinick EH, Dae M, Krishnan R, Ewing S. Hypertrophic cardiomyopathy in the young: another form of ischemic cardiomyopathy? J Am Coll Cardiol. 1993 Sep; 22(3):805-7. PMID: 8354815.
      View in: PubMed
    54. Krishnan R, Lu J, Zhu YY, Dae M, Botvinick EH. Myocardial perfusion scintigraphy in left bundle branch block: a perspective on the issue from image analysis in a clinical context. Am Heart J. 1993 Sep; 126(3 Pt 1):578-86. PMID: 8362712.
      View in: PubMed
    55. Lucas JR, Botvinick EH, Dae M. Myocardial viability: evidence provided by the analysis of left ventricular systolic function. Coron Artery Dis. 1993 Jun; 4(6):485-94. PMID: 8261226.
      View in: PubMed
    56. Oka RK, Stotts NA, Dae M, Haskell WL, Gortner SR. Daily physical activity levels in congestive heart failure. Am J Cardiol. 1993 Apr 15; 71(11):921-5. PMID: 8465782.
      View in: PubMed
    57. Starksen NF, O'Connell W, Dae M, Botvinick EH. Basal interventricular septal thallium-201 defects: real or artifact? Clin Nucl Med. 1993 Apr; 18(4):291-7. PMID: 8482025.
      View in: PubMed
    58. Botvinick EH, Zhu YY, O'Connell WJ, Dae M. A quantitative assessment of patient motion and its effect on myocardial perfusion SPECT images. J Nucl Med. 1993 Feb; 34(2):303-10. PMID: 8429354.
      View in: PubMed
    59. Munoz del Romeral L, Dae M, Ports TA, Botvinick EH. Diagnostic and prognostic value of ambulatory electrocardiographic monitoring. Am Heart J. 1992 Nov; 124(5):1213-9. PMID: 1442488.
      View in: PubMed
    60. Fischbein NJ, Dae M, Sandler ED. A unique finding on I-123 MIBG imaging: pericardial effusion. Clin Nucl Med. 1992 Sep; 17(9):745. PMID: 1395354.
      View in: PubMed
    61. Dae M, De Marco T, Botvinick EH, O'Connell JW, Hattner RS, Huberty JP, Yuen-Green MS. Scintigraphic assessment of MIBG uptake in globally denervated human and canine hearts--implications for clinical studies. J Nucl Med. 1992 Aug; 33(8):1444-50. PMID: 1634934.
      View in: PubMed
    62. Botvinick EH, Dae M. Dipyridamole perfusion scintigraphy. Semin Nucl Med. 1991 Jul; 21(3):242-65. PMID: 1948114.
      View in: PubMed
    63. Watters TA, Botvinick EH, Dae M, Cahalan M, Urbanowicz J, Benefiel DJ, Schiller NB, Goldstone G, Reilly L, Stoney RJ. Comparison of the findings on preoperative dipyridamole perfusion scintigraphy and intraoperative transesophageal echocardiography: implications regarding the identification of myocardium at ischemic risk. J Am Coll Cardiol. 1991 Jul; 18(1):93-100. PMID: 2050947.
      View in: PubMed
    64. Oeff M, Scheinman MM, Abbott JA, Botvinick EH, Griffin JC, Herre JM, Dae M. Phase image triangulation of accessory pathways in patients undergoing catheter ablation of posteroseptal pathways. Pacing Clin Electrophysiol. 1991 Jun; 14(6):1072-85. PMID: 1715068.
      View in: PubMed
    65. Dae M, Herre JM, O'Connell JW, Botvinick EH, Newman D, Munoz L. Scintigraphic assessment of sympathetic innervation after transmural versus nontransmural myocardial infarction. J Am Coll Cardiol. 1991 May; 17(6):1416-23. PMID: 2016460.
      View in: PubMed
    66. Rosenqvist M, Isaaz K, Botvinick EH, Dae M, Cockrell J, Abbott JA, Schiller NB, Griffin JC. Relative importance of activation sequence compared to atrioventricular synchrony in left ventricular function. Am J Cardiol. 1991 Jan 15; 67(2):148-56. PMID: 1987716.
      View in: PubMed
    67. Zhu YY, Chung WS, Botvinick EH, Dae M, Lim AD, Ports TA, Danforth JW, Wolfe CL, Goldschlager N, Chatterjee K. Dipyridamole perfusion scintigraphy: the experience with its application in one hundred seventy patients with known or suspected unstable angina. Am Heart J. 1991 Jan; 121(1 Pt 1):33-43. PMID: 1985375.
      View in: PubMed
    68. Dae M, Botvinick EH. Imaging of the heart using metaiodobenzylguanidine. J Thorac Imaging. 1990 Jul; 5(3):31-6. PMID: 2194039.
      View in: PubMed
    69. Urbanowicz JH, Shaaban MJ, Cohen NH, Cahalan MK, Botvinick EH, Chatterjee K, Schiller NB, Dae M, Matthay MA. Comparison of transesophageal echocardiographic and scintigraphic estimates of left ventricular end-diastolic volume index and ejection fraction in patients following coronary artery bypass grafting. Anesthesiology. 1990 Apr; 72(4):607-12. PMID: 2321775.
      View in: PubMed
    70. Mori H, Pisarri TE, Aldea GS, Husseini WK, Dae M, Stevens MB, Hill AC, Coleridge JC, Coleridge HM, Hoffman JI. Usefulness and limitations of regional cardiac sympathectomy by phenol. Am J Physiol. 1989 Nov; 257(5 Pt 2):H1523-33. PMID: 2574007.
      View in: PubMed
    71. Botvinick EH, Dae M, O'Connell JW. Blood pool scintigraphy. Cardiol Clin. 1989 Aug; 7(3):537-63. PMID: 2670226.
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    72. Verrier ED, Crombleholme TM, Sauer L, Longaker M, Langer JC, Flake AW, Dae M, Brem H, Harrison MR. Neonatal model of heterotopic heart transplantation in pigs. J Thorac Cardiovasc Surg. 1989 Jul; 98(1):127-35; discussion 135-6. PMID: 2661923.
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    73. Dae M, Wen YM, Botvinick EH, Scheinman M. ECG left anterior fascicular block reveals diverse patterns on scintigraphic phase analysis. Am Heart J. 1989 Apr; 117(4):861-9. PMID: 2929402.
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    74. Schechtmann N, Botvinick EH, Dae M, Scheinman MM, O'Connell JW, Davis J, Winston S, Schwartz A, Abbott J. The scintigraphic characteristics of ventricular pre-excitation through Mahaim fibers with the use of phase analysis. J Am Coll Cardiol. 1989 Mar 15; 13(4):882-91. PMID: 2494242.
      View in: PubMed
    75. Dae M, O'Connell JW, Botvinick EH, Ahearn T, Yee E, Huberty JP, Mori H, Chin MC, Hattner RS, Herre JM. Scintigraphic assessment of regional cardiac adrenergic innervation. Circulation. 1989 Mar; 79(3):634-44. PMID: 2783894.
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    76. Zhu YY, Lee W, Botvinick E, Dae M, Chatterjee K, Danforth J, Ports T. The clinical and pathophysiologic implications of pain, ST abnormalities, and scintigraphic changes induced during dipyridamole infusion: their relationships to the peripheral hemodynamic response. Am Heart J. 1988 Oct; 116(4):1071-80. PMID: 3177178.
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    77. Zhu YY, Botvinick E, Dae M, Golden J, Hattner R, Scheinman M. Gallium lung scintigraphy in amiodarone pulmonary toxicity. Chest. 1988 Jun; 93(6):1126-31. PMID: 3371091.
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    78. Botvinick EH, Dae M. Dipyridamole myocardial perfusion scintigraphy. West J Med. 1988 Apr; 148(4):454-5. PMID: 18750408.
      View in: PubMed
    79. Botvinick EH, O'Connell WJ, Dae M, Hattner RS, Schechtmann NM. Analysis of thallium-201 "washout" from parametric color coded images. J Nucl Med. 1988 Mar; 29(3):302-10. PMID: 3346740.
      View in: PubMed
    80. Herre JM, Wetstein L, Lin YL, Mills AS, Dae M, Thames MD. Effect of transmural versus nontransmural myocardial infarction on inducibility of ventricular arrhythmias during sympathetic stimulation in dogs. J Am Coll Cardiol. 1988 Feb; 11(2):414-21. PMID: 3339182.
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    81. Botvinick E, Schechtmann N, Dae M, Scheinman M, Davis J, Herre J, Iskikian T, Abbott J. Augmented preexcitation assessed by scintigraphic phase analysis during atrial pacing. Am Heart J. 1987 Oct; 114(4 Pt 1):738-45. PMID: 3661363.
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    82. Martin GR, Soifer SJ, Silverman NH, Dae M, Stanger P. Effects of activity on ascending aortic velocity in children with valvar aortic stenosis. Am J Cardiol. 1987 Jun 01; 59(15):1386-90. PMID: 3591696.
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    83. Axelrod RJ, De Marco T, Dae M, Botvinick EH, Chatterjee K. Hemodynamic and clinical evaluation of piroximone, a new inotrope-vasodilator agent, in severe congestive heart failure. J Am Coll Cardiol. 1987 May; 9(5):1124-30. PMID: 3571752.
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    84. Blumlein S, Bouchard A, Schiller NB, Dae M, Byrd BF, Ports T, Botvinick EH. Quantitation of mitral regurgitation by Doppler echocardiography. Circulation. 1986 Aug; 74(2):306-14. PMID: 3731421.
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    85. Canhasi B, Dae M, Botvinick E, Lanzer P, Schechtmann N, Faulkner D, O'Connell W, Schiller N. Interaction of "supplementary" scintigraphic indicators of ischemia and stress electrocardiography in the diagnosis of multivessel coronary disease. J Am Coll Cardiol. 1985 Sep; 6(3):581-8. PMID: 4031268.
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    86. Viquerat CE, Hansen RM, Botvinick EH, Dae M, Wiener-Kronish JP, Matthay MA. Undrained bloody pericardial effusion in the early postoperative period after coronary bypass surgery: a prospective blood pool study. Am Heart J. 1985 Aug; 110(2):335-41. PMID: 3875274.
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    87. Wahr DW, Ports TA, Botvinick EH, Dae M, Schechtmann N, Huberty J, Hattner RS, O'Connell JW, Turley K. The effects of coronary angioplasty and reperfusion on distribution of myocardial flow. Circulation. 1985 Aug; 72(2):334-43. PMID: 3159510.
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    88. Dae M, Canhasi B, Botvinick E, Olvera S, Schechtmann N, Engelstad B, Hattner R, Schiller N, O'Connell W, Faulkner D. The etiology and implications of dense cavitary "photopenia" on myocardial perfusion scintigraphy. Invest Radiol. 1985 Jul; 20(4):388-92. PMID: 4044180.
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    89. Carmona RH, Tsao T, Dae M, Trunkey DD. Myocardial dysfunction in septic shock. Arch Surg. 1985 Jan; 120(1):30-5. PMID: 2981522.
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    90. Frais M, Botvinick E, Shosa D, O'Connell W, Pacheco Alvarez J, Dae M, Hattner R, Faulkner D. Phase image characterization of localized and generalized left ventricular contraction abnormalities. J Am Coll Cardiol. 1984 Nov; 4(5):987-98. PMID: 6491089.
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    91. Botvinick E, Frais M, O'Connell W, Faulkner D, Scheinman M, Morady F, Sung R, Shosa D, Dae M. Phase image evaluation of patients with ventricular pre-excitation syndromes. J Am Coll Cardiol. 1984 Mar; 3(3):799-814. PMID: 6693651.
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    92. Dae M, Botvinick EH. Characterization of conduction and concentration abnormalities by scintigraphic phase analysis. Int J Cardiol. 1984 Feb; 5(2):244-53. PMID: 6698652.
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    93. Reuss ML, Rudolph AM, Dae M. Phasic blood flow patterns in the superior and inferior venae cavae and umbilical vein of fetal sheep. Am J Obstet Gynecol. 1983 Jan 01; 145(1):70-8. PMID: 6849346.
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    94. Dae M, Heymann MA, Jones AL. A new technique for perfusion fixation and contrast enhancement of foetal lamb myocardium for electron microscopy. J Microsc. 1982 Sep; 127(Pt 3):301-5. PMID: 6194301.
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