Jacqueline Leung, MD, MPH

Title(s)Professor, Anesthesia
SchoolSchool of Medicine
Address521 Parnassus Avenue
San Francisco CA 94117
Phone415-476-0711
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    Collapse Biography 
    Collapse Education and Training
    University of California, San Francisco Clinical Fellowship Cardiology
    University of California, San FranciscoResidency
    Stanford UniversityM.D.1984School of Medicine

    Collapse Overview 
    Collapse Overview
    Dr. Leung is the director of the Perioperative Medicine Research Group based at UCSF Medical Center. The group conducts outcomes research in older surgical patients. Our recent work focuses on identifying the pathophysiology of postoperative delirium and cognitive decline, and also the mechanism between sleep disruption and ICU delirium.

    Collapse Research 
    Collapse Research Activities and Funding
    The role of genomics in postoperative delirium and sedation
    NIH R01NR017622Sep 24, 2019 - Jul 31, 2022
    Role: Principal Investigator
    Acute preoperative sleep disruption and postoperative delirium
    NIH R21AG053715Mar 1, 2017 - Feb 29, 2020
    Role: Principal Investigator
    The Effects of Light vs Deep Anesthesia on Postoperative Cognitive Outcomes
    NIH R21AG048456Jun 1, 2015 - May 31, 2018
    Role: Principal Investigator
    Pathophysiology of postoperative delirium in older patients
    NIH R01AG031795Sep 15, 2009 - Jul 31, 2015
    Role: Principal Investigator
    AGING AND PERIOPERATIVE OUTCOMES
    NIH K24AG000948Mar 1, 2001 - Feb 28, 2006
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials
    Collapse Faculty Mentoring
    Collapse Student Projects
    Collapse Academic Senate

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Midazolam Premedication Immediately Before Surgery Is Not Associated With Early Postoperative Delirium. Anesth Analg. 2021 Mar 15. Wang ML, Min J, Sands LP, Leung JM, Perioperative Medicine Research Group . PMID: 33721875.
      View in: PubMed   Mentions:    Fields:    
    2. Prion-induced photoreceptor degeneration begins with misfolded prion protein accumulation in cones at two distinct sites: cilia and ribbon synapses. Acta Neuropathol Commun. 2021 01 29; 9(1):17. Striebel JF, Race B, Leung JM, Schwartz C, Chesebro B. PMID: 33509294.
      View in: PubMed   Mentions:    Fields:    
    3. Does postoperative delirium following elective noncardiac surgery predict long-term mortality? Age Ageing. 2020 10 23; 49(6):1020-1027. Ziman N, Sands LP, Tang C, Zhu J, Leung JM. PMID: 32232435.
      View in: PubMed   Mentions:    Fields:    
    4. ADAPT-2: A Randomized Clinical Trial to Reduce Intraoperative EEG Suppression in Older Surgical Patients Undergoing Major Noncardiac Surgery. Anesth Analg. 2020 10; 131(4):1228-1236. Tang CJ, Jin Z, Sands LP, Pleasants D, Tabatabai S, Hong Y, Leung JM. PMID: 32925344.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    5. American Society for Enhanced Recovery and Perioperative Quality Initiative Joint Consensus Statement on Postoperative Delirium Prevention. Anesth Analg. 2020 06; 130(6):1572-1590. Hughes CG, Boncyk CS, Culley DJ, Fleisher LA, Leung JM, McDonagh DL, Gan TJ, McEvoy MD, Miller TE, Perioperative Quality Initiative (POQI) 6 Workgroup . PMID: 32022748.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    6. ADAPT-2: A Randomized Clinical Trial to Reduce Intraoperative EEG Suppression in Older Surgical Patients Undergoing Major Noncardiac Surgery. Anesth Analg. 2020 Mar 09. Tang CJ, Jin Z, Sands LP, Pleasants D, Tabatabai S, Hong Y, Leung JM. PMID: 32167975.
      View in: PubMed   Mentions:    Fields:    
    7. Adherence to recommended practices for perioperative anesthesia care for older adults among US anesthesiologists: results from the ASA Committee on Geriatric Anesthesia-Perioperative Brain Health Initiative ASA member survey. Perioper Med (Lond). 2020; 9:6. Deiner S, Fleisher LA, Leung JM, Peden C, Miller T, Neuman MD, ASA Committee on Geriatric Anesthesia and the ASA Perioperative Brain Health Initiative . PMID: 32123562.
      View in: PubMed   Mentions:
    8. Processed Electroencephalogram Monitoring and Postoperative Delirium: A Systematic Review and Meta-analysis. Anesthesiology. 2018 09; 129(3):417-427. MacKenzie KK, Britt-Spells AM, Sands LP, Leung JM. PMID: 29912008.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    9. Volatile anaesthetics and postoperative delirium in older surgical patients-A secondary analysis of prospective cohort studies. Acta Anaesthesiol Scand. 2019 01; 63(1):18-26. Kinjo S, Lim E, Magsaysay MV, Sands LP, Leung JM, Perioperative Medicine Research Group . PMID: 30051465.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    10. Perioperative Gabapentin Does Not Reduce Postoperative Delirium in Older Surgical Patients: A Randomized Clinical Trial. Anesthesiology. 2017 10; 127(4):633-644. Leung JM, Sands LP, Chen N, Ames C, Berven S, Bozic K, Burch S, Chou D, Covinsky K, Deviren V, Kinjo S, Kramer JH, Ries M, Tay B, Vail T, Weinstein P, Chang S, Meckler G, Newman S, Tsai T, Voss V, Youngblom E, Perioperative Medicine Research Group . PMID: 28727581.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    11. Validation of a Nurse-Based Delirium-Screening Tool for Hospitalized Patients. Psychosomatics. 2017 Nov - Dec; 58(6):594-603. Hargrave A, Bastiaens J, Bourgeois JA, Neuhaus J, Josephson SA, Chinn J, Lee M, Leung J, Douglas V. PMID: 28750835.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansPHPublic Health
    12. Burst-suppression ratio underestimates absolute duration of electroencephalogram suppression compared with visual analysis of intraoperative electroencephalogram. Br J Anaesth. 2017 May 01; 118(5):755-761. Muhlhofer WG, Zak R, Kamal T, Rizvi B, Sands LP, Yuan M, Zhang X, Leung JM. PMID: 28486575.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    13. The Feasibility and Utility of Continuous Sleep Monitoring in Critically Ill Patients Using a Portable Electroencephalography Monitor. Anesth Analg. 2016 07; 123(1):206-12. Vacas S, McInrue E, Gropper MA, Maze M, Zak R, Lim E, Leung JM. PMID: 27159066.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    14. Preoperative Sleep Disruption and Postoperative Delirium. J Clin Sleep Med. 2015 Aug 15; 11(8):907-13. Leung JM, Sands LP, Newman S, Meckler G, Xie Y, Gay C, Lee K. PMID: 25979094.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    15. Prognostic Significance of Postoperative Subsyndromal Delirium. Psychosomatics. 2015 Nov-Dec; 56(6):644-51. Shim J, DePalma G, Sands LP, Leung JM. PMID: 26198571.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    16. Impact of intraoperative hypotension and blood pressure fluctuations on early postoperative delirium after non-cardiac surgery. Br J Anaesth. 2015 Sep; 115(3):418-26. Hirsch J, DePalma G, Tsai TT, Sands LP, Leung JM. PMID: 25616677.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    17. Sensitivity and specificity of the animal fluency test for predicting postoperative delirium. Can J Anaesth. 2015 Jun; 62(6):603-8. Long LS, Wolpaw JT, Leung JM. PMID: 25537737.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    18. American Geriatrics Society abstracted clinical practice guideline for postoperative delirium in older adults. J Am Geriatr Soc. 2015 Jan; 63(1):142-50. American Geriatrics Society Expert Panel on Postoperative Delirium in Older Adults . PMID: 25495432.
      View in: PubMed   Mentions: 66     Fields:    Translation:Humans
    19. Postoperative delirium in older adults: best practice statement from the American Geriatrics Society. J Am Coll Surg. 2015 Feb; 220(2):136-48.e1. American Geriatrics Society Expert Panel on Postoperative Delirium in Older Adults . PMID: 25535170.
      View in: PubMed   Mentions: 68     Fields:    Translation:Humans
    20. The temporal relationship between early postoperative delirium and postoperative cognitive dysfunction in older patients: a prospective cohort study. Can J Anaesth. 2014 Dec; 61(12):1084-92. Youngblom E, DePalma G, Sands L, Leung J. PMID: 25287962.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    21. Does preoperative risk for delirium moderate the effects of postoperative pain and opiate use on postoperative delirium? Am J Geriatr Psychiatry. 2013 Oct; 21(10):946-56. Leung JM, Sands LP, Lim E, Tsai TL, Kinjo S. PMID: 23659900.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    22. Association between intraoperative blood transfusions and early postoperative delirium in older adults. J Am Geriatr Soc. 2013 Mar; 61(3):365-70. Behrends M, DePalma G, Sands L, Leung J. PMID: 23496244.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    23. Impact of missing data on analysis of postoperative cognitive decline (POCD). Appl Nurs Res. 2013 May; 26(2):71-5. DeCrane SK, Sands LP, Young KM, DePalma G, Leung JM. PMID: 23290047.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    24. An update on delirium in the postoperative setting: prevention, diagnosis and management. Best Pract Res Clin Anaesthesiol. 2012 Sep; 26(3):327-43. Shim JJ, Leung JM. PMID: 23040284.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    25. A brief review of practical preoperative cognitive screening tools. Can J Anaesth. 2012 Aug; 59(8):798-804. Long LS, Shapiro WA, Leung JM. PMID: 22638676.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansPHPublic Health
    26. Does using a femoral nerve block for total knee replacement decrease postoperative delirium? BMC Anesthesiol. 2012 Mar 10; 12:4. Kinjo S, Lim E, Sands LP, Bozic KJ, Leung JM. PMID: 22405052.
      View in: PubMed   Mentions: 5     Fields:    
    27. Prediction of postoperative pain using path analysis in older patients. J Anesth. 2012 Feb; 26(1):1-8. Kinjo S, Sands LP, Lim E, Paul S, Leung JM. PMID: 22012171.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    28. Perioperative cognitive decline in the aging population. Mayo Clin Proc. 2011 Sep; 86(9):885-93. Terrando N, Brzezinski M, Degos V, Eriksson LI, Kramer JH, Leung JM, Miller BL, Seeley WW, Vacas S, Weiner MW, Yaffe K, Young WL, Xie Z, Maze M. PMID: 21878601.
      View in: PubMed   Mentions: 54     Fields:    Translation:Humans
    29. Factors associated with recovery from early postoperative delirium. J Perianesth Nurs. 2011 Aug; 26(4):231-41. DeCrane SK, Sands L, Ashland M, Lim E, Tsai TL, Paul S, Leung JM. PMID: 21803271.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    30. Brief report: preoperative frailty in older surgical patients is associated with early postoperative delirium. Anesth Analg. 2011 May; 112(5):1199-201. Leung JM, Tsai TL, Sands LP. PMID: 21372278.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    31. Postoperative delirium: are there modifiable risk factors? Eur J Anaesthesiol. 2010 May; 27(5):403-5. Leung JM. PMID: 20386385.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    32. Long-term cognitive decline: is there a link to surgery and anesthesia? Anesthesiology. 2009 Nov; 111(5):931-2. Leung JM, Sands LP. PMID: 19786857.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    33. Does postoperative delirium limit the use of patient-controlled analgesia in older surgical patients? Anesthesiology. 2009 Sep; 111(3):625-31. Leung JM, Sands LP, Paul S, Joseph T, Kinjo S, Tsai T. PMID: 19672166.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    34. Apolipoprotein E e4 allele increases the risk of early postoperative delirium in older patients undergoing noncardiac surgery. Anesthesiology. 2007 Sep; 107(3):406-11. Leung JM, Sands LP, Wang Y, Poon A, Kwok PY, Kane JP, Pullinger CR. PMID: 17721242.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    35. The effects of postoperative pain and its management on postoperative cognitive dysfunction. Am J Geriatr Psychiatry. 2007 Jan; 15(1):50-9. Wang Y, Sands LP, Vaurio L, Mullen EA, Leung JM. PMID: 17194815.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    36. Histologic assessment of right atrial appendage myocardium in patients with atrial fibrillation after coronary artery bypass graft surgery. Cardiology. 2007; 108(2):90-6. Nakai T, Chandy J, Nakai K, Bellows WH, Flachsbart K, Lee RJ, Leung JM. PMID: 17008797.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    37. Pilot clinical trial of gabapentin to decrease postoperative delirium in older patients. Neurology. 2006 Oct 10; 67(7):1251-3. Leung JM, Sands LP, Rico M, Petersen KL, Rowbotham MC, Dahl JB, Ames C, Chou D, Weinstein P. PMID: 16914695.
      View in: PubMed   Mentions: 36     Fields:    Translation:Humans
    38. Nitrous oxide does not change the incidence of postoperative delirium or cognitive decline in elderly surgical patients. Br J Anaesth. 2006 Jun; 96(6):754-60. Leung JM, Sands LP, Vaurio LE, Wang Y. PMID: 16670110.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    39. The role of postoperative analgesia in delirium and cognitive decline in elderly patients: a systematic review. Anesth Analg. 2006 Apr; 102(4):1255-66. Fong HK, Sands LP, Leung JM. PMID: 16551934.
      View in: PubMed   Mentions: 63     Fields:    Translation:Humans
    40. Postoperative delirium: the importance of pain and pain management. Anesth Analg. 2006 Apr; 102(4):1267-73. Vaurio LE, Sands LP, Wang Y, Mullen EA, Leung JM. PMID: 16551935.
      View in: PubMed   Mentions: 73     Fields:    Translation:Humans
    41. Are preoperative depressive symptoms associated with postoperative delirium in geriatric surgical patients? J Gerontol A Biol Sci Med Sci. 2005 Dec; 60(12):1563-8. Leung JM, Sands LP, Mullen EA, Wang Y, Vaurio L. PMID: 16424289.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    42. Impairment of left atrial function predicts post-operative atrial fibrillation after coronary artery bypass graft surgery. Eur Heart J. 2004 Oct; 25(20):1836-44. Leung JM, Bellows WH, Schiller NB. PMID: 15474699.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    43. Does intraoperative evaluation of left ventricular contractile reserve predict myocardial viability? A clinical study using dobutamine stress echocardiography in patients undergoing coronary artery bypass graft surgery. Anesth Analg. 2004 Sep; 99(3):647-54, table of contents. Leung JM, Bellows WH, Pastor D. PMID: 15333387.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    44. Increases in P-wave dispersion predict postoperative atrial fibrillation after coronary artery bypass graft surgery. Anesth Analg. 2004 Feb; 98(2):303-10, table of contents. Chandy J, Nakai T, Lee RJ, Bellows WH, Dzankic S, Leung JM. PMID: 14742359.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCTClinical Trials
    45. The prevalence of preoperative diastolic filling abnormalities in geriatric surgical patients. Anesth Analg. 2003 Nov; 97(5):1214-21. Phillip B, Pastor D, Bellows W, Leung JM. PMID: 14570626.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCTClinical Trials
    46. Prognostic significance of postoperative in-hospital complications in elderly patients. I. Long-term survival. Anesth Analg. 2003 Feb; 96(2):583-9, table of contents. Manku K, Bacchetti P, Leung JM. PMID: 12538216.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    47. Prognostic significance of postoperative in-hospital complications in elderly patients. II. Long-term quality of life. Anesth Analg. 2003 Feb; 96(2):590-4, table of contents. Manku K, Leung JM. PMID: 12538217.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    48. Preoperative electrocardiogram abnormalities do not predict postoperative cardiac complications in geriatric surgical patients. J Am Geriatr Soc. 2002 Jul; 50(7):1186-91. Liu LL, Dzankic S, Leung JM. PMID: 12133011.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    49. Comparison of left atrial dimensions by transesophageal and transthoracic echocardiography. J Am Soc Echocardiogr. 2002 Feb; 15(2):143-9. Block M, Hourigan L, Bellows WH, Reeves J, Romson JL, Tran M, Pastor D, Schiller NB, Leung JM. PMID: 11836489.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    50. The relative importance of left atrial function versus dimension in predicting atrial fibrillation after coronary artery bypass graft surgery. Am Heart J. 2002 Jan; 143(1):181-6. Nakai T, Lee RJ, Schiller NB, Bellows WH, Dzankic S, Reeves J, Romson J, Ferguson S, Leung JM. PMID: 11773931.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    51. The prevalence and predictors of the use of alternative medicine in presurgical patients in five California hospitals. Anesth Analg. 2001 Oct; 93(4):1062-8. Leung JM, Dzankic S, Manku K, Yuan S. PMID: 11574384.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    52. Relative importance of preoperative health status versus intraoperative factors in predicting postoperative adverse outcomes in geriatric surgical patients. J Am Geriatr Soc. 2001 Aug; 49(8):1080-5. Leung JM, Dzankic S. PMID: 11555070.
      View in: PubMed   Mentions: 61     Fields:    Translation:Humans
    53. The prevalence and predictive value of abnormal preoperative laboratory tests in elderly surgical patients. Anesth Analg. 2001 Aug; 93(2):301-8, 2nd contents page. Dzankic S, Pastor D, Gonzalez C, Leung JM. PMID: 11473849.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    54. Electrocardiographic ST-segment changes during acute, severe isovolemic hemodilution in humans. Anesthesiology. 2000 Oct; 93(4):1004-10. Leung JM, Weiskopf RB, Feiner J, Hopf HW, Kelley S, Viele M, Lieberman J, Watson J, Noorani M, Pastor D, Yeap H, Ho R, Toy P. PMID: 11020755.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    55. Predicting adverse postoperative outcomes in patients aged 80 years or older. J Am Geriatr Soc. 2000 Apr; 48(4):405-12. Liu LL, Leung JM. PMID: 10798467.
      View in: PubMed   Mentions: 34     Fields:    Translation:Humans
    56. Critical oxygen delivery in conscious humans is less than 7.3 ml O2 x kg(-1) x min(-1). Anesthesiology. 2000 Feb; 92(2):407-13. Lieberman JA, Weiskopf RB, Kelley SD, Feiner J, Noorani M, Leung J, Toy P, Viele M. PMID: 10691227.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCTClinical Trials
    57. Effects of dobutamine on hemodynamics and left ventricular performance after cardiopulmonary bypass in cardiac surgical patients. Anesthesiology. 1999 Nov; 91(5):1318-28. Romson JL, Leung JM, Bellows WH, Bronstein M, Keith F, Moores W, Flachsbart K, Richter R, Pastor D, Fisher DM. PMID: 10551583.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCTClinical Trials
    58. Automated electrocardiograph ST segment trending monitors: accuracy in detecting myocardial ischemia. Anesth Analg. 1998 Jul; 87(1):4-10. Leung JM, Voskanian A, Bellows WH, Pastor D. PMID: 9661536.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCTClinical Trials
    59. Dissociation between haemodynamics and sympathetic activation during anaesthetic induction with desfluranes. Can J Anaesth. 1998 Jun; 45(6):533-40. Leung JM, Pastor DA. PMID: 9669006.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCTClinical Trials
    60. Human cardiovascular and metabolic response to acute, severe isovolemic anemia. JAMA. 1998 Jan 21; 279(3):217-21. Weiskopf RB, Viele MK, Feiner J, Kelley S, Lieberman J, Noorani M, Leung JM, Fisher DM, Murray WR, Toy P, Moore MA. PMID: 9438742.
      View in: PubMed   Mentions: 74     Fields:    Translation:Humans
    61. Transesophageal echocardiography in myocardial revascularization: I. Accuracy of intraoperative real-time interpretation. Anesth Analg. 1996 Jun; 82(6):1132-8. Bergquist BD, Leung JM, Bellows WH. PMID: 8638780.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCTClinical Trials
    62. Transesophageal echocardiography in myocardial revascularization: II. Influence on intraoperative decision making. Anesth Analg. 1996 Jun; 82(6):1139-45. Bergquist BD, Bellows WH, Leung JM. PMID: 8638781.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCTClinical Trials
    63. Effects of acadesine on the incidence of myocardial infarction and adverse cardiac outcomes after coronary artery bypass graft surgery. Multicenter Study of Perioperative Ischemia (McSPI) Research Group. Anesthesiology. 1995 Oct; 83(4):658-73. PMID: 7574044.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCTClinical Trials
    64. Effects of perioperative dexmedetomidine infusion in patients undergoing vascular surgery. The Study of Perioperative Ischemia Research Group. Anesthesiology. 1995 Mar; 82(3):620-33. Talke P, Li J, Jain U, Leung J, Drasner K, Hollenberg M, Mangano DT. PMID: 7879930.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCTClinical Trials
    65. Left ventricular end-systolic cavity obliteration as an estimate of intraoperative hypovolemia. Anesthesiology. 1994 Nov; 81(5):1102-9. Leung JM, Levine EH. PMID: 7978468.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    66. Relationship of the proinflammatory cytokines to myocardial ischemia and dysfunction after uncomplicated coronary revascularization. J Thorac Cardiovasc Surg. 1994 Oct; 108(4):626-35. Hennein HA, Ebba H, Rodriguez JL, Merrick SH, Keith FM, Bronstein MH, Leung JM, Mangano DT, Greenfield LJ, Rankin JS. PMID: 7934095.
      View in: PubMed   Mentions: 51     Fields:    Translation:Humans
    67. Safety and efficacy of intravenous Carbicarb in patients undergoing surgery: comparison with sodium bicarbonate in the treatment of mild metabolic acidosis. SPI Research Group. Study of Perioperative Ischemia. Crit Care Med. 1994 Oct; 22(10):1540-9. Leung JM, Landow L, Franks M, Soja-Strzepa D, Heard SO, Arieff AI, Mangano DT. PMID: 7924363.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCTClinical Trials
    68. An initial multicenter, randomized controlled trial on the safety and efficacy of acadesine in patients undergoing coronary artery bypass graft surgery. SPI Research Group. Anesth Analg. 1994 Mar; 78(3):420-34. Leung JM, Stanley T, Mathew J, Curling P, Barash P, Salmenpera M, Reves JG, Hollenberg M, Mangano DT. PMID: 7818622.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCTClinical Trials
    69. Safety of low-dose intraoperative bicarbonate therapy: a prospective, double-blind, randomized study. The Study of Perioperative Ischemia (SPI) Research Group. Crit Care Med. 1993 May; 21(5):659-65. Mark NH, Leung JM, Arieff AI, Mangano DT. PMID: 8386997.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCTClinical Trials
    70. Clinical evidence of myocardial stunning in patients undergoing CABG surgery. J Card Surg. 1993 Mar; 8(2 Suppl):220-3. Leung JM. PMID: 8461506.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    71. Effects of steal-prone anatomy on intraoperative myocardial ischemia. The SPI Research Group. J Am Coll Cardiol. 1992 Nov 01; 20(5):1205-12. Leung JM, Hollenberg M, O'Kelly BF, Kao A, Mangano DT. PMID: 1401623.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    72. Monitoring for myocardial ischemia during noncardiac surgery. A technology assessment of transesophageal echocardiography and 12-lead electrocardiography. The Study of Perioperative Ischemia Research Group. JAMA. 1992 Jul 08; 268(2):210-6. Eisenberg MJ, London MJ, Leung JM, Browner WS, Hollenberg M, Tubau JF, Tateo IM, Schiller NB, Mangano DT. PMID: 1608139.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    73. The risk of myocardial ischemia in patients receiving desflurane versus sufentanil anesthesia for coronary artery bypass graft surgery. The S.P.I. Research Group. Anesthesiology. 1992 Jul; 77(1):47-62. Helman JD, Leung JM, Bellows WH, Pineda N, Roach GW, Reeves JD, Howse J, McEnany MT, Mangano DT. PMID: 1535185.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    74. Postoperative myocardial ischemia. Therapeutic trials using intensive analgesia following surgery. The Study of Perioperative Ischemia (SPI) Research Group. Anesthesiology. 1992 Mar; 76(3):342-53. Mangano DT, Siliciano D, Hollenberg M, Leung JM, Browner WS, Goehner P, Merrick S, Verrier E. PMID: 1531742.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCTClinical Trials
    75. Ventricular dysrhythmias in patients undergoing coronary artery bypass graft surgery: incidence, characteristics, and prognostic importance. Study of Perioperative Ischemia (SPI) Research Group. Am Heart J. 1992 Jan; 123(1):73-81. Smith RC, Leung JM, Keith FM, Merrick S, Mangano DT. PMID: 1370363.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
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