-
Evidence Against Use of Nitrogen for the Death Penalty. JAMA. 2024 06 25; 331(24):2075-2076.
Bickler PE, Lipnick MS. PMID: 38809524.
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PubMed Mentions: Fields:
Translation:
Humans
-
The performance of 11 fingertip pulse oximeters during hypoxemia in healthy human participants with varied, quantified skin pigment. EBioMedicine. 2024 Apr; 102:105051.
Leeb G, Auchus I, Law T, Bickler P, Feiner J, Hashi S, Monk E, Igaga E, Bernstein M, Chou YC, Hughes C, Schornack D, Lester J, Moore K, Okunlola O, Fernandez J, Shmuylovich L, Lipnick M. PMID: 38458110; PMCID: PMC10943300.
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PubMed Mentions:
2 Fields:
Translation:
Humans
-
Low Perfusion and Missed Diagnosis of Hypoxemia by Pulse Oximetry in Darkly Pigmented Skin: A Prospective Study. Anesth Analg. 2024 Mar 01; 138(3):552-561.
Gudelunas MK, Lipnick M, Hendrickson C, Vanderburg S, Okunlola B, Auchus I, Feiner JR, Bickler PE. PMID: 38109495.
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PubMed Mentions:
1 Fields:
Translation:
Humans
-
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Mismatched opioid prescription in patients discharged after neurological surgeries: a retrospective cohort study. Pain. 2023 Nov 01; 164(11):2615-2621.
Campbell LJ, Mummaneni PV, Letchuman V, Langnas E, Agarwal N, Guan LS, Croci R, Vargas E, Reisner L, Bickler P, Chou D, Chang E, Guan Z. PMID: 37326642.
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PubMed Mentions: Fields:
-
Quantifying pulse oximeter accuracy during hypoxemia and severe anemia using an in vitro circulation system. J Clin Monit Comput. 2023 12; 37(6):1441-1449.
Gylys R, Feiner J, Pologe J, Delianides T, Sutter S, Bickler P, Lipnick MS. PMID: 37266710; PMCID: PMC10651532.
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PubMed Mentions: Fields:
Translation:
Humans
-
Neuromuscular Weakness and Paralysis Produced by Snakebite Envenoming: Mechanisms and Proposed Standards for Clinical Assessment. Toxins (Basel). 2023 01 06; 15(1).
Bickler PE, Abouyannis M, Bhalla A, Lewin MR. PMID: 36668869; PMCID: PMC9861841.
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PubMed Mentions:
3 Fields:
Translation:
Humans
-
Bilateral Superficial Trigeminal Nerve Blocks are not More Effective than a Placebo in Abolishing Post-operative Headache Pain in Pituitary Transsphenoidal Neurosurgery: A Prospective, Randomized, Doubleblinded Clinical Trial. Rev Recent Clin Trials. 2023; 18(3):228-237.
Srejic U, Litonius E, Gandhi S, Talke P, Maties O, Siegmueller C, Magsaysay A, Hasen D, Kunwar S, Seth R, Gibson L, Bickler P. PMID: 36843368; PMCID: PMC10514508.
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PubMed Mentions: Fields:
Translation:
HumansCTClinical Trials
-
Pulse Oximeter Bias and Inequities in Retrospective Studies--Now What? Respir Care. 2022 12; 67(12):1633-1636.
Moore KL, Gudelunas K, Lipnick MS, Bickler PE, Hendrickson CM. PMID: 36442988.
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PubMed Mentions:
2 Fields:
Translation:
Humans
-
Varespladib in the Treatment of Snakebite Envenoming: Development History and Preclinical Evidence Supporting Advancement to Clinical Trials in Patients Bitten by Venomous Snakes. Toxins (Basel). 2022 11 11; 14(11).
Lewin MR, Carter RW, Matteo IA, Samuel SP, Rao S, Fry BG, Bickler PE. PMID: 36422958; PMCID: PMC9695340.
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PubMed Mentions:
12 Fields:
Translation:
Humans
-
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
-
The Pulse Oximeter Is Amazing, but Not Perfect. Anesthesiology. 2022 05 01; 136(5):670-671.
Bickler P, Tremper KK. PMID: 35303063.
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PubMed Mentions:
1 Fields:
-
Neuroanatomical Basis for the Orexinergic Modulation of Anesthesia Arousal and Pain Control. Front Cell Neurosci. 2022; 16:891631.
Xiang X, Chen Y, Li KX, Fang J, Bickler PE, Guan Z, Zhou W. PMID: 35558876; PMCID: PMC9090436.
View in:
PubMed Mentions:
2
-
Pulse Oximeter Performance, Racial Inequity, and the Work Ahead. Respir Care. 2022 02; 67(2):252-257.
Okunlola OE, Lipnick MS, Batchelder PB, Bernstein M, Feiner JR, Bickler PE. PMID: 34772785.
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PubMed Mentions:
25 Fields:
Translation:
Humans
-
John W. Severinghaus, M.D., 1922 to 2021. Anesthesiology. 2021 10 01; 135(4):555-557.
Bickler PE, Hornbein T, Saidman LJ. PMID: 34499145.
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PubMed Mentions:
1 Fields:
Translation:
Humans
-
Association between tissue oxygenation and myocardial injury in patients undergoing major spine surgery: a prospective cohort study. BMJ Open. 2021 09 17; 11(9):e044342.
Bernholm KF, Meyhoff CS, Bickler P. PMID: 34535471; PMCID: PMC8451303.
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PubMed Mentions: Fields:
Translation:
Humans
-
Extremes of age are associated with differences in the expression of selected pattern recognition receptor genes and ACE2, the receptor for SARS-CoV-2: implications for the epidemiology of COVID-19 disease. BMC Med Genomics. 2021 05 24; 14(1):138.
Bickler SW, Cauvi DM, Fisch KM, Prieto JM, Sykes AG, Thangarajah H, Lazar DA, Ignacio RC, Gerstmann DR, Ryan AF, Bickler PE, De Maio A. PMID: 34030677; PMCID: PMC8142073.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
-
Accuracy of Samsung Smartphone Integrated Pulse Oximetry Meets Full FDA Clearance Standards for Clinical Use. medRxiv. 2021 Feb 18.
Browne SH, Bernstein M, Bickler PE. PMID: 33619504; PMCID: PMC7899474.
View in:
PubMed Mentions:
2
-
"Silent" Presentation of Hypoxemia and Cardiorespiratory Compensation in COVID-19. Anesthesiology. 2021 02 01; 134(2):262-269.
Bickler PE, Feiner JR, Lipnick MS, McKleroy W. PMID: 32970134; PMCID: PMC7523476.
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PubMed Mentions:
22 Fields:
Translation:
HumansCells
-
Amplification of Snake Venom Toxicity by Endogenous Signaling Pathways. Toxins (Basel). 2020 01 22; 12(2).
Bickler PE. PMID: 31979014; PMCID: PMC7076764.
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PubMed Mentions:
29 Fields:
Translation:
HumansAnimalsCells
-
Intraoperative physiological ranges associated with improved outcomes after major spine surgery: an observational study. BMJ Open. 2019 05 28; 9(5):e025337.
Li G, Lin L, Xiao J, Rosenbaum S, Bickler P, Meng L. PMID: 31142521; PMCID: PMC6549674.
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PubMed Mentions:
1 Fields:
Translation:
Humans
-
Delayed LY333013 (Oral) and LY315920 (Intravenous) Reverse Severe Neurotoxicity and Rescue Juvenile Pigs from Lethal Doses of Micrurus fulvius (Eastern Coral Snake) Venom. Toxins (Basel). 2018 Nov 17; 10(11).
Lewin MR, Gilliam LL, Gilliam J, Samuel SP, Bulfone TC, Bickler PE, Gutiérrez JM. PMID: 30453607; PMCID: PMC6265968.
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PubMed Mentions:
31 Fields:
Translation:
Animals
-
Activation of orexin system facilitates anesthesia emergence and pain control. Proc Natl Acad Sci U S A. 2018 11 06; 115(45):E10740-E10747.
Zhou W, Cheung K, Kyu S, Wang L, Guan Z, Kurien PA, Bickler PE, Jan LY. PMID: 30348769; PMCID: PMC6233126.
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PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
-
Delayed Oral LY333013 Rescues Mice from Highly Neurotoxic, Lethal Doses of Papuan Taipan (Oxyuranus scutellatus) Venom. Toxins (Basel). 2018 09 20; 10(10).
Lewin MR, Gutiérrez JM, Samuel SP, Herrera M, Bryan-Quirós W, Lomonte B, Bickler PE, Bulfone TC, Williams DJ. PMID: 30241297; PMCID: PMC6215158.
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PubMed Mentions:
32 Fields:
Translation:
Animals
-
Response to Burtscher re: "Increased Cytokines at High Altitude: Lack of Effect of Ibuprofen on Acute Mountain Sickness, Physiological Variables, or Cytokine Levels". High Alt Med Biol. 2018 09; 19(3):304-305.
Bickler P, Feiner JR, Lundeberg J. PMID: 30239230.
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PubMed Mentions: Fields:
Translation:
Humans
-
Developing Small Molecule Therapeutics for the Initial and Adjunctive Treatment of Snakebite. J Trop Med. 2018; 2018:4320175.
Bulfone TC, Samuel SP, Bickler PE, Lewin MR. PMID: 30154870; PMCID: PMC6091453.
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PubMed Mentions:
30
-
Increased Cytokines at High Altitude: Lack of Effect of Ibuprofen on Acute Mountain Sickness, Physiological Variables, or Cytokine Levels. High Alt Med Biol. 2018 Sep; 19(3):249-258.
Lundeberg J, Feiner JR, Schober A, Sall JW, Eilers H, Bickler PE. PMID: 29924642.
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PubMed Mentions:
16 Fields:
Translation:
Humans
-
Four Types of Pulse Oximeters Accurately Detect Hypoxia during Low Perfusion and Motion. Anesthesiology. 2018 03; 128(3):520-530.
Louie A, Feiner JR, Bickler PE, Rhodes L, Bernstein M, Lucero J. PMID: 29200008.
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PubMed Mentions:
32 Fields:
Translation:
Humans
-
Comparison of Transcranial Doppler and Ultrasound-Tagged Near Infrared Spectroscopy for Measuring Relative Changes in Cerebral Blood Flow in Human Subjects. Anesth Analg. 2018 02; 126(2):579-587.
Lipnick MS, Cahill EA, Feiner JR, Bickler PE. PMID: 29189269.
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PubMed Mentions:
2 Fields:
Translation:
Humans
-
Effects of Changes in Arterial Carbon Dioxide and Oxygen Partial Pressures on Cerebral Oximeter Performance. Anesthesiology. 2018 01; 128(1):97-108.
Schober A, Feiner JR, Bickler PE, Rollins MD. PMID: 29084012.
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PubMed Mentions:
7 Fields:
Translation:
Humans
-
Reduction in N-methyl-D-aspartate Receptor-mediated Cell Death in Hippocampal Neurons by Glucose Reduction Preconditioning. J Neurosurg Anesthesiol. 2017 Oct; 29(4):448-457.
Yang N, Gabatto P, Bickler PE. PMID: 28368913.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
-
Little Black Boxes: Noncardiac Implantable Electronic Medical Devices and Their Anesthetic and Surgical Implications. Anesth Analg. 2017 07; 125(1):124-138.
Srejic U, Larson P, Bickler PE. PMID: 28489640.
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PubMed Mentions:
3 Fields:
Translation:
Humans
-
Interaction of Isoflurane, Tumor Necrosis Factor-α and β-Amyloid on Long-term Potentiation in Rat Hippocampal Slices. Anesth Analg. 2017 02; 124(2):582-587.
Zhou R, Bickler P. PMID: 28099324.
View in:
PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
-
Effects of Acute, Profound Hypoxia on Healthy Humans: Implications for Safety of Tests Evaluating Pulse Oximetry or Tissue Oximetry Performance. Anesth Analg. 2017 01; 124(1):146-153.
Bickler PE, Feiner JR, Lipnick MS, Batchelder P, MacLeod DB, Severinghaus JW. PMID: 27529318.
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PubMed Mentions:
30 Fields:
Translation:
HumansAnimals
-
Tissue Oximetry and Clinical Outcomes. Anesth Analg. 2017 01; 124(1):72-82.
Bickler P, Feiner J, Rollins M, Meng L. PMID: 27308951.
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PubMed Mentions:
24 Fields:
Translation:
Humans
-
Trends and Challenges in Clinical Monitoring: Papers From the 2015 IAMPOV Symposium. Anesth Analg. 2017 01; 124(1):2-3.
Bickler PE, Cannesson M, Shelley KH. PMID: 27551739.
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PubMed Mentions:
1 Fields:
Translation:
Humans
-
Varespladib (LY315920) Appears to Be a Potent, Broad-Spectrum, Inhibitor of Snake Venom Phospholipase A2 and a Possible Pre-Referral Treatment for Envenomation. Toxins (Basel). 2016 08 25; 8(9).
Lewin M, Samuel S, Merkel J, Bickler P. PMID: 27571102; PMCID: PMC5037474.
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PubMed Mentions:
87 Fields:
Translation:
Animals
-
The Accuracy of 6 Inexpensive Pulse Oximeters Not Cleared by the Food and Drug Administration: The Possible Global Public Health Implications. Anesth Analg. 2016 08; 123(2):338-45.
Lipnick MS, Feiner JR, Au P, Bernstein M, Bickler PE. PMID: 27089002.
View in:
PubMed Mentions:
44 Fields:
Translation:
HumansPHPublic Health
-
Enough Information to Evaluate Clinical Monitors? Anesth Analg. 2016 07; 123(1):254-5.
Bickler PE. PMID: 27314698.
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PubMed Mentions: Fields:
-
The Accuracy of Pulse Spectroscopy for Detecting Hypoxemia and Coexisting Methemoglobin or Carboxyhemoglobin. Anesth Analg. 2016 06; 122(6):1856-65.
Kulcke A, Feiner J, Menn I, Holmer A, Hayoz J, Bickler P. PMID: 27111642.
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PubMed Mentions:
3 Fields:
Translation:
Humans
-
Hypoxic preconditioning and cell death from oxygen/glucose deprivation co-opt a subset of the unfolded protein response in hippocampal neurons. Neuroscience. 2015 Dec 03; 310:306-21.
Bickler PE, Clark JP, Gabatto P, Brosnan H. PMID: 26404874.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
-
Early Treatment with Intranasal Neostigmine Reduces Mortality in a Mouse Model of Naja naja (Indian Cobra) Envenomation. J Trop Med. 2014; 2014:131835.
Lewin MR, Samuel SP, Wexler DS, Bickler P, Vaiyapuri S, Mensh BD. PMID: 24955095; PMCID: PMC4052076.
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PubMed Mentions:
4
-
Limitations of Mild, Moderate, and Profound Hypothermia in Protecting Developing Hippocampal Neurons After Simulated Ischemia. Ther Hypothermia Temp Manag. 2013 Dec 01; 3(4):178-188.
Gregersen M, Lee DH, Gabatto P, Bickler PE. PMID: 24380031; PMCID: PMC3868300.
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PubMed Mentions:
2 Fields:
-
Factors affecting the performance of 5 cerebral oximeters during hypoxia in healthy volunteers. Anesth Analg. 2013 Oct; 117(4):813-823.
Bickler PE, Feiner JR, Rollins MD. PMID: 24023027.
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PubMed Mentions:
63 Fields:
Translation:
Humans
-
Accuracy of the Lifebox pulse oximeter during hypoxia in healthy volunteers. Anaesthesia. 2013 Dec; 68(12):1220-3.
Dubowitz G, Breyer K, Lipnick M, Sall JW, Feiner J, Ikeda K, MacLeod DB, Bickler PE. PMID: 23992483.
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PubMed Mentions:
11 Fields:
Translation:
Humans
-
Xenon neurotoxicity in rat hippocampal slice cultures is similar to isoflurane and sevoflurane. Anesthesiology. 2013 Aug; 119(2):335-44.
Brosnan H, Bickler PE. PMID: 23591069.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
-
Reversal of experimental paralysis in a human by intranasal neostigmine aerosol suggests a novel approach to the early treatment of neurotoxic envenomation. Clin Case Rep. 2013 Oct; 1(1):7-15.
Lewin MR, Bickler P, Heier T, Feiner J, Montauk L, Mensh B. PMID: 25356201; PMCID: PMC4184533.
View in:
PubMed Mentions:
4
-
Accuracy of carboxyhemoglobin detection by pulse CO-oximetry during hypoxemia. Anesth Analg. 2013 Oct; 117(4):847-858.
Feiner JR, Rollins MD, Sall JW, Eilers H, Au P, Bickler PE. PMID: 23477959; PMCID: PMC4476500.
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PubMed Mentions:
13 Fields:
Translation:
Humans
-
Propofol at clinically relevant concentrations increases neuronal differentiation but is not toxic to hippocampal neural precursor cells in vitro. Anesthesiology. 2012 Nov; 117(5):1080-90.
Sall JW, Stratmann G, Leong J, Woodward E, Bickler PE. PMID: 23001052; PMCID: PMC3483886.
View in:
PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
-
Anesthetic protection of neurons injured by hypothermia and rewarming: roles of intracellular Ca2+ and excitotoxicity. Anesthesiology. 2012 Aug; 117(2):280-92.
Bickler PE, Warren DE, Clark JP, Gabatto P, Gregersen M, Brosnan H. PMID: 22728782; PMCID: PMC3428020.
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PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
-
Delayed environmental enrichment reverses sevoflurane-induced memory impairment in rats. Anesthesiology. 2012 Mar; 116(3):586-602.
Shih J, May LD, Gonzalez HE, Lee EW, Alvi RS, Sall JW, Rau V, Bickler PE, Lalchandani GR, Yusupova M, Woodward E, Kang H, Wilk AJ, Carlston CM, Mendoza MV, Guggenheim JN, Schaefer M, Rowe AM, Stratmann G. PMID: 22354242; PMCID: PMC4146425.
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PubMed Mentions:
64 Fields:
Translation:
Animals
-
The emergence level of the musculocutaneous nerve from the brachial plexus: implications for infraclavicular nerve blocks. Anesth Analg. 2012 May; 114(5):1131-3.
Pianezza A, Salces y Nedeo A, Chaynes P, Bickler PE, Minville V. PMID: 22312122.
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PubMed Mentions:
5 Fields:
Translation:
Humans
-
Hypothermia and rewarming injury in hippocampal neurons involve intracellular Ca2+ and glutamate excitotoxicity. Neuroscience. 2012 Apr 05; 207:316-25.
Warren DE, Bickler PE, Clark JP, Gregersen M, Brosnan H, McKleroy W, Gabatto P. PMID: 22265728.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
-
Hypoxic preconditioning failure in aging hippocampal neurons: impaired gene expression and rescue with intracellular calcium chelation. J Neurosci Res. 2010 Dec; 88(16):3520-9.
Bickler PE, Fahlman CS, Gray JJ. PMID: 20936695.
View in:
PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
-
Improved accuracy of methemoglobin detection by pulse CO-oximetry during hypoxia. Anesth Analg. 2010 Nov; 111(5):1160-7.
Feiner JR, Bickler PE. PMID: 20841412.
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PubMed Mentions:
13 Fields:
Translation:
Humans
-
Enhanced hypoxic preconditioning by isoflurane: signaling gene expression and requirement of intracellular Ca2+ and inositol triphosphate receptors. Brain Res. 2010 Jun 22; 1340:86-95.
Bickler PE, Fahlman CS. PMID: 20434434; PMCID: PMC3478070.
View in:
PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
-
Antifreeze protein suppresses spontaneous neural activity and protects neurons from hypothermia/re-warming injury. Neurosci Res. 2010 Jul; 67(3):256-9.
Rubinsky L, Raichman N, Lavee J, Frenk H, Ben-Jacob E, Bickler PE. PMID: 20398707.
View in:
PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
-
Isoflurane does not affect brain cell death, hippocampal neurogenesis, or long-term neurocognitive outcome in aged rats. Anesthesiology. 2010 Feb; 112(2):305-15.
Stratmann G, Sall JW, Bell JS, Alvi RS, May Ld, Ku B, Dowlatshahi M, Dai R, Bickler PE, Russell I, Lee MT, Hrubos MW, Chiu C. PMID: 20098132; PMCID: PMC5214622.
View in:
PubMed Mentions:
36 Fields:
Translation:
AnimalsCells
-
Erythropoietin promotes hippocampal neurogenesis in in vitro models of neonatal stroke. Neurobiol Dis. 2010 May; 38(2):259-65.
Osredkar D, Sall JW, Bickler PE, Ferriero DM. PMID: 20117210; PMCID: PMC2854222.
View in:
PubMed Mentions:
33 Fields:
Translation:
AnimalsCells
-
Accuracy of methemoglobin detection by pulse CO-oximetry during hypoxia. Anesth Analg. 2010 Jul; 111(1):143-8.
Feiner JR, Bickler PE, Mannheimer PD. PMID: 20007731.
View in:
PubMed Mentions:
17 Fields:
Translation:
Humans
-
Expression of signal transduction genes differs after hypoxic or isoflurane preconditioning of rat hippocampal slice cultures. Anesthesiology. 2009 Aug; 111(2):258-66.
Bickler PE, Fahlman CS. PMID: 19568165; PMCID: PMC3478094.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
-
Consensus statement: First International Workshop on Anesthetics and Alzheimer's disease. Anesth Analg. 2009 May; 108(5):1627-30.
Baranov D, Bickler PE, Crosby GJ, Culley DJ, Eckenhoff MF, Eckenhoff RG, Hogan KJ, Jevtovic-Todorovic V, Palotás A, Perouansky M, Planel E, Silverstein JH, Wei H, Whittington RA, Xie Z, Zuo Z, First International Workshop on Anesthetics and Alzheimer's Disease. PMID: 19372347; PMCID: PMC2769511.
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PubMed Mentions:
51 Fields:
Translation:
HumansAnimals
-
Inositol 1,4,5-triphosphate receptors and NAD(P)H mediate Ca2+ signaling required for hypoxic preconditioning of hippocampal neurons. Neuroscience. 2009 Apr 21; 160(1):51-60.
Bickler PE, Fahlman CS, Gray J, McKleroy W. PMID: 19217932; PMCID: PMC2684521.
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PubMed Mentions:
21 Fields:
Translation:
AnimalsCells
-
Arctic ground squirrel (Spermophilus parryii) hippocampal neurons tolerate prolonged oxygen-glucose deprivation and maintain baseline ERK1/2 and JNK activation despite drastic ATP loss. J Cereb Blood Flow Metab. 2008 Jul; 28(7):1307-19.
Christian SL, Ross AP, Zhao HW, Kristenson HJ, Zhan X, Rasley BT, Bickler PE, Drew KL. PMID: 18398417; PMCID: PMC2792705.
View in:
PubMed Mentions:
24 Fields:
Translation:
AnimalsCells
-
Dark skin decreases the accuracy of pulse oximeters at low oxygen saturation: the effects of oximeter probe type and gender. Anesth Analg. 2007 Dec; 105(6 Suppl):S18-S23.
Feiner JR, Severinghaus JW, Bickler PE. PMID: 18048893.
View in:
PubMed Mentions:
122 Fields:
Translation:
Humans
-
Hypoxia tolerance in reptiles, amphibians, and fishes: life with variable oxygen availability. Annu Rev Physiol. 2007; 69:145-70.
Bickler PE, Buck LT. PMID: 17037980.
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PubMed Mentions:
171 Fields:
Translation:
Animals
-
Bleeding complications from femoral and sciatic nerve catheters in patients receiving low molecular weight heparin. Anesth Analg. 2006 Oct; 103(4):1036-7.
Bickler P, Brandes J, Lee M, Bozic K, Chesbro B, Claassen J. PMID: 17000826.
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PubMed Mentions:
13 Fields:
Translation:
Humans
-
The inhaled anesthetic, isoflurane, enhances Ca2+-dependent survival signaling in cortical neurons and modulates MAP kinases, apoptosis proteins and transcription factors during hypoxia. Anesth Analg. 2006 Aug; 103(2):419-29, table of contents.
Bickler PE, Fahlman CS. PMID: 16861427.
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PubMed Mentions:
36 Fields:
Translation:
AnimalsCells
-
Isoflurane neuroprotection in rat hippocampal slices decreases with aging: changes in intracellular Ca2+ regulation and N-methyl-D-aspartate receptor-mediated Ca2+ influx. Anesthesiology. 2006 May; 104(5):995-1003.
Zhan X, Fahlman CS, Bickler PE. PMID: 16645452.
View in:
PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
-
Improvised cricothyrotomy provides reliable airway access in an unembalmed human cadaver model. Wilderness Environ Med. 2006; 17(2):81-6.
Platts-Mills TF, Lewin MR, Wells J, Bickler P. PMID: 16805143.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Isoflurane preconditions hippocampal neurons against oxygen-glucose deprivation: role of intracellular Ca2+ and mitogen-activated protein kinase signaling. Anesthesiology. 2005 Sep; 103(3):532-9.
Bickler PE, Zhan X, Fahlman CS. PMID: 16129978.
View in:
PubMed Mentions:
46 Fields:
Translation:
AnimalsCells
-
Effects of skin pigmentation on pulse oximeter accuracy at low saturation. Anesthesiology. 2005 Apr; 102(4):715-9.
Bickler PE, Feiner JR, Severinghaus JW. PMID: 15791098.
View in:
PubMed Mentions:
99 Fields:
Translation:
HumansCTClinical Trials
-
Isoflurane neuroprotection in hypoxic hippocampal slice cultures involves increases in intracellular Ca2+ and mitogen-activated protein kinases. Anesthesiology. 2005 Mar; 102(3):606-15.
Gray JJ, Bickler PE, Fahlman CS, Zhan X, Schuyler JA. PMID: 15731600.
View in:
PubMed Mentions:
37 Fields:
Translation:
AnimalsCells
-
Intracellular calcium and survival of tadpole forebrain cells in anoxia. J Exp Biol. 2005 Feb; 208(Pt 4):681-6.
Hedrick MS, Fahlman CS, Bickler PE. PMID: 15695760.
View in:
PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
-
Protective effects of TASK-3 (KCNK9) and related 2P K channels during cellular stress. Brain Res. 2005 Jan 21; 1031(2):164-73.
Liu C, Cotten JF, Schuyler JA, Fahlman CS, Au JD, Bickler PE, Yost CS. PMID: 15649441.
View in:
PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
-
Mild hypothermia, but not propofol, is neuroprotective in organotypic hippocampal cultures. Anesth Analg. 2005 Jan; 100(1):215-225.
Feiner JR, Bickler PE, Estrada S, Donohoe PH, Fahlman CS, Schuyler JA. PMID: 15616081.
View in:
PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
-
Clinical perspectives: neuroprotection lessons from hypoxia-tolerant organisms. J Exp Biol. 2004 Aug; 207(Pt 18):3243-9.
Bickler PE. PMID: 15299045.
View in:
PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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Falsely low pulse oximetry values in patients receiving docetaxel (Taxotere). Anesth Analg. 2004 Aug; 99(2):622-3.
Paige M, Bickler PE. PMID: 15271755.
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PubMed Mentions:
2 Fields:
Translation:
Humans
-
Hypoxia increases calcium flux through cortical neuron glutamate receptors via protein kinase C. J Neurochem. 2004 Feb; 88(4):878-84.
Bickler PE, Fahlman CS, Ferriero DM. PMID: 14756808.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
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Moderate increases in intracellular calcium activate neuroprotective signals in hippocampal neurons. Neuroscience. 2004; 127(3):673-83.
Bickler PE, Fahlman CS. PMID: 15283966.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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gamma-Aminobutyric acid-A receptors contribute to isoflurane neuroprotection in organotypic hippocampal cultures. Anesth Analg. 2003 Aug; 97(2):564-571.
Bickler PE, Warner DS, Stratmann G, Schuyler JA. PMID: 12873954.
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PubMed Mentions:
15 Fields:
Translation:
Animals
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Oxygen sensitivity of NMDA receptors: relationship to NR2 subunit composition and hypoxia tolerance of neonatal neurons. Neuroscience. 2003; 118(1):25-35.
Bickler PE, Fahlman CS, Taylor DM. PMID: 12676134.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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Activation of the neuroprotective ERK signaling pathway by fructose-1,6-bisphosphate during hypoxia involves intracellular Ca2+ and phospholipase C. Brain Res. 2002 Dec 20; 958(1):43-51.
Fahlman CS, Bickler PE, Sullivan B, Gregory GA. PMID: 12468029.
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PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
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Adaptive responses of vertebrate neurons to hypoxia. J Exp Biol. 2002 Dec; 205(Pt 23):3579-86.
Bickler PE, Donohoe PH. PMID: 12409484.
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PubMed Mentions:
29 Fields:
Translation:
AnimalsCells
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Molecular adaptations for survival during anoxia: lessons from lower vertebrates. Neuroscientist. 2002 Jun; 8(3):234-42.
Bickler PE, Donohoe PH, Buck LT. PMID: 12061503.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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Comparison of the effects of cyclosporin a on the metabolism of perfused rat brain slices during normoxia and hypoxia. J Cereb Blood Flow Metab. 2002 Mar; 22(3):342-52.
Serkova N, Donohoe P, Gottschalk S, Hainz C, Niemann CU, Bickler PE, Litt L, Benet LZ, Leibfritz D, Christians U. PMID: 11891440.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Isoflurane prevents delayed cell death in an organotypic slice culture model of cerebral ischemia. Anesthesiology. 2002 Jan; 96(1):189-95.
Sullivan BL, Leu D, Taylor DM, Fahlman CS, Bickler PE. PMID: 11753020.
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PubMed Mentions:
16 Fields:
Translation:
Animals
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Neuroprotection and intracellular Ca2+ modulation with fructose-1,6-bisphosphate during in vitro hypoxia-ischemia involves phospholipase C-dependent signaling. Brain Res. 2001 Nov 02; 917(2):158-66.
Donohoe PH, Fahlman CS, Bickler PE, Vexler ZS, Gregory GA. PMID: 11640901.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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The reversal of fentanyl-induced tolerance by administration of "small-dose" ketamine. Anesth Analg. 2001 Jul; 93(1):213-4.
Eilers H, Philip LA, Bickler PE, McKay WR, Schumacher MA. PMID: 11429368.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Effects of neuroprotective cocktails on hippocampal neuron death in an in vitro model of cerebral ischemia. J Neurosurg Anesthesiol. 2001 Jan; 13(1):19-25.
Liniger R, Popovic R, Sullivan B, Gregory G, Bickler PE. PMID: 11145473.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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Hypoxia-induced silencing of NMDA receptors in turtle neurons. J Neurosci. 2000 May 15; 20(10):3522-8.
Bickler PE, Donohoe PH, Buck LT. PMID: 10804192; PMCID: PMC6772670.
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PubMed Mentions:
31 Fields:
Translation:
AnimalsCells
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Anesthetics and mild hypothermia similarly prevent hippocampal neuron death in an in vitro model of cerebral ischemia. Anesthesiology. 2000 May; 92(5):1343-9.
Popovic R, Liniger R, Bickler PE. PMID: 10781280.
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PubMed Mentions:
21 Fields:
Translation:
AnimalsCells
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Halothane, but not the nonimmobilizers perfluoropentane and 1,2-dichlorohexafluorocyclobutane, depresses synaptic transmission in hippocampal CA1 neurons in rats. Anesth Analg. 1999 Oct; 89(4):1040-5.
Taylor DM, Eger EI, Bickler PE. PMID: 10512287.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Different effects of volatile anesthetics and polyhalogenated alkanes on depolarization-evoked glutamate release in rat cortical brain slices. Anesth Analg. 1999 May; 88(5):1168-74.
Eilers H, Kindler CH, Bickler PE. PMID: 10320189.
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PubMed Mentions:
7 Fields:
Translation:
Animals
-
Volatile anesthetics increase intracellular calcium in cerebrocortical and hippocampal neurons. Anesthesiology. 1999 Apr; 90(4):1137-45.
Kindler CH, Eilers H, Donohoe P, Ozer S, Bickler PE. PMID: 10201687.
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PubMed Mentions:
15 Fields:
Translation:
Animals
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Reversible decreases in ATP and PCr concentrations in anoxic turtle brain. Comp Biochem Physiol A Mol Integr Physiol. 1998 Aug; 120(4):633-9.
Buck L, Espanol M, Litt L, Bickler P. PMID: 9828395.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Reduction of NMDA receptor activity in cerebrocortex of turtles (Chrysemys picta) during 6 wk of anoxia. Am J Physiol. 1998 07; 275(1):R86-91.
Bickler PE. PMID: 9688964.
View in:
PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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Adaptations of vertebrate neurons to hypoxia and anoxia: maintaining critical Ca2+ concentrations. J Exp Biol. 1998 Apr; 201(Pt 8):1141-52.
Bickler PE, Buck LT. PMID: 9510526.
View in:
PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Hypoxia-tolerant neonatal CA1 neurons: relationship of survival to evoked glutamate release and glutamate receptor-mediated calcium changes in hippocampal slices. Brain Res Dev Brain Res. 1998 Mar 12; 106(1-2):57-69.
Bickler PE, Hansen BM. PMID: 9554954.
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PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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Dual effects of anandamide on NMDA receptor-mediated responses and neurotransmission. J Neurochem. 1998 Feb; 70(2):671-6.
Hampson AJ, Bornheim LM, Scanziani M, Yost CS, Gray AT, Hansen BM, Leonoudakis DJ, Bickler PE. PMID: 9453561.
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PubMed Mentions:
51 Fields:
Translation:
AnimalsCells
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Adenosine and anoxia reduce N-methyl-D-aspartate receptor open probability in turtle cerebrocortex. J Exp Biol. 1998 Jan; 201(Pt 2):289-97.
Buck LT, Bickler PE. PMID: 9405320.
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PubMed Mentions:
20 Fields:
Translation:
Animals
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Functional deactivation of the major neuronal nicotinic receptor caused by nicotine and a protein kinase C-dependent mechanism. Mol Pharmacol. 1997 Dec; 52(6):1105-12.
Eilers H, Schaeffer E, Bickler PE, Forsayeth JR. PMID: 9415721.
View in:
PubMed Mentions:
19 Fields:
Translation:
HumansCells
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Interactive effects of pH and temperature on N-methyl-D-aspartate receptor activity in rat cortical brain slices. J Neurosurg Anesthesiol. 1997 Apr; 9(2):180-7.
Gray AT, Buck LT, Feiner JR, Bickler PE. PMID: 9100191.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
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Effects of fructose-1,6-bisphosphate on glutamate release and ATP loss from rat brain slices during hypoxia. J Neurochem. 1996 Oct; 67(4):1463-8.
Bickler PE, Buck LT. PMID: 8858928.
View in:
PubMed Mentions:
8 Fields:
Translation:
Animals
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Effects of dexmedetomidine on hypoxia-evoked glutamate release and glutamate receptor activity in hippocampal slices. Anesthesiology. 1996 Sep; 85(3):551-7.
Talke P, Bickler PE. PMID: 8853085.
View in:
PubMed Mentions:
13 Fields:
Translation:
Animals
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Hypothermia and isoflurane similarly inhibit glutamate release evoked by chemical anoxia in rat cortical brain slices. Anesthesiology. 1996 Sep; 85(3):600-7.
Eilers H, Bickler PE. PMID: 8853091.
View in:
PubMed Mentions:
8 Fields:
Translation:
Animals
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Pulmonary hemodynamic response to exercise in subjects with prior high-altitude pulmonary edema. J Appl Physiol (1985). 1996 Aug; 81(2):911-21.
Eldridge MW, Podolsky A, Richardson RS, Johnson DH, Knight DR, Johnson EC, Hopkins SR, Michimata H, Grassi B, Feiner J, Kurdak SS, Bickler PE, Wagner PD, Severinghaus JW. PMID: 8872663.
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PubMed Mentions:
21 Fields:
Translation:
HumansCTClinical Trials
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Exercise-induced VA/Q inequality in subjects with prior high-altitude pulmonary edema. J Appl Physiol (1985). 1996 Aug; 81(2):922-32.
Podolsky A, Eldridge MW, Richardson RS, Knight DR, Johnson EC, Hopkins SR, Johnson DH, Michimata H, Grassi B, Feiner J, Kurdak SS, Bickler PE, Severinghaus JW, Wagner PD. PMID: 8872664.
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PubMed Mentions:
19 Fields:
Translation:
HumansCTClinical Trials
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Alpha 2-adrenergic agonists reduce glutamate release and glutamate receptor-mediated calcium changes in hippocampal slices during hypoxia. Neuropharmacology. 1996 Jun; 35(6):679-87.
Bickler PE, Hansen BM. PMID: 8887976.
View in:
PubMed Mentions:
13 Fields:
Translation:
Animals
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Volatile and intravenous anesthetics decrease glutamate release from cortical brain slices during anoxia. Anesthesiology. 1995 Dec; 83(6):1233-40.
Bickler PE, Buck LT, Feiner JR. PMID: 8533916.
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PubMed Mentions:
10 Fields:
Translation:
Animals
-
Role of adenosine in NMDA receptor modulation in the cerebral cortex of an anoxia-tolerant turtle (Chrysemys picta belli). J Exp Biol. 1995 Jul; 198(Pt 7):1621-8.
Buck LT, Bickler PE. PMID: 7658192.
View in:
PubMed Mentions:
4 Fields:
Translation:
Animals
-
Hypoxic ventilatory response predicts the extent of maximal breath-holds in man. Respir Physiol. 1995 Jun; 100(3):213-22.
Feiner JR, Bickler PE, Severinghaus JW. PMID: 7481110.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Causes of calcium accumulation in rat cortical brain slices during hypoxia and ischemia: role of ion channels and membrane damage. Brain Res. 1994 Dec 05; 665(2):269-76.
Bickler PE, Hansen BM. PMID: 7534604.
View in:
PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Effects of isoflurane and hypothermia on glutamate receptor-mediated calcium influx in brain slices. Anesthesiology. 1994 Dec; 81(6):1461-9.
Bickler PE, Buck LT, Hansen BM. PMID: 7992916.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Time course of augmentation and depression of hypoxic ventilatory responses at altitude. J Appl Physiol (1985). 1994 Jul; 77(1):313-6.
Sato M, Severinghaus JW, Bickler P. PMID: 7961252.
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PubMed Mentions:
21 Fields:
Translation:
HumansCellsCTClinical Trials
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Activation of brain acetylcholine receptors by neuromuscular blocking drugs. A possible mechanism of neurotoxicity. Anesthesiology. 1994 May; 80(5):1155-61; discussion 29A.
Cardone C, Szenohradszky J, Yost S, Bickler PE. PMID: 7912481.
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PubMed Mentions:
7 Fields:
Translation:
Animals
-
Influence of pH on calcium influx during hypoxia in rat cortical brain slices. Stroke. 1994 Jan; 25(1):171-7.
O'Donnell BR, Bickler PE. PMID: 8266367.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Developmental changes in intracellular calcium regulation in rat cerebral cortex during hypoxia. J Cereb Blood Flow Metab. 1993 Sep; 13(5):811-9.
Bickler PE, Gallego SM, Hansen BM. PMID: 8103057.
View in:
PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Inhibition of brain calcium channels by plasma proteins from anoxic turtles. Am J Physiol. 1993 Aug; 265(2 Pt 2):R277-81.
Bickler PE, Gallego SM. PMID: 8103641.
View in:
PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Central nervous system effects of intrathecal muscle relaxants in rats. Anesth Analg. 1993 Jun; 76(6):1304-9.
Szenohradszky J, Trevor AJ, Bickler P, Caldwell JE, Sharma ML, Rampil IJ, Miller RD. PMID: 8098920.
View in:
PubMed Mentions:
4 Fields:
Translation:
Animals
-
Cerebral anoxia tolerance in turtles: regulation of intracellular calcium and pH. Am J Physiol. 1992 Dec; 263(6 Pt 2):R1298-302.
Bickler PE. PMID: 1481942.
View in:
PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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Fructose-1,6-bisphosphate stabilizes brain intracellular calcium during hypoxia in rats. Stroke. 1992 Nov; 23(11):1617-22.
Bickler PE, Kelleher JA. PMID: 1440710.
View in:
PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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Regional cerebral blood flow and tissue oxygenation during hypocarbia in geese. Am J Physiol. 1992 Aug; 263(2 Pt 2):R221-5.
Bickler PE, Julian D. PMID: 1510162.
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PubMed Mentions:
3 Fields:
Translation:
Animals
-
Mass spectrometers and infrared gas analyzers interpret bronchodilator propellants as anesthetic gases. Anesth Analg. 1992 Jul; 75(1):142-3.
Bickler PE, Sohn YJ. PMID: 1616143.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Effects of temperature and anoxia on regional cerebral blood flow in turtles. Am J Physiol. 1992 Mar; 262(3 Pt 2):R538-41.
Bickler PE. PMID: 1558224.
View in:
PubMed Mentions:
2 Fields:
Translation:
Animals
-
Intracranial pressure and brain redox balance in rabbits. Can J Anaesth. 1991 Jul; 38(5):654-9.
Bissonnette B, Bickler PE, Gregory GA, Severinghaus JW. PMID: 1934221.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Intralipid solution mistakenly infused into epidural space. Anesth Analg. 1990 Dec; 71(6):712-3.
Bickler P, Spears R, McKay W. PMID: 2240651.
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PubMed Mentions: Fields:
Translation:
Humans
-
Efficiency of airway heat and moisture exchangers in anesthetized humans. Anesth Analg. 1990 Oct; 71(4):415-8.
Bickler PE, Sessler DI. PMID: 2400121.
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PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Acute radial nerve injury from use of an automatic blood pressure monitor. Anesthesiology. 1990 Jul; 73(1):186-8.
Bickler PE, Schapera A, Bainton CR. PMID: 2360731.
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PubMed Mentions:
13 Fields:
Translation:
Humans
-
Diffusion of felt-tip marker pen ink into intravenous bags. Anesth Analg. 1989 Sep; 69(3):412.
Bickler PE, Gold B, Johnson BH. PMID: 2774247.
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PubMed Mentions: Fields:
-
Effects of hypoxia and hypocapnia on brain redox balance in ducks. Am J Physiol. 1989 Jul; 257(1 Pt 2):R132-5.
Bickler PE, Koh SO, Severinghaus JW. PMID: 2502033.
View in:
PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Effects of acetazolamide on cerebral acid-base balance. J Appl Physiol (1985). 1988 Jul; 65(1):422-7.
Bickler PE, Litt L, Banville DL, Severinghaus JW. PMID: 3136134.
View in:
PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
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Effects of acetazolamide on cerebrocortical NADH and blood volume. J Appl Physiol (1985). 1988 Jul; 65(1):428-33.
Bickler PE, Litt L, Severinghaus JW. PMID: 3136135.
View in:
PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Effects of barbiturate anesthesia on functional residual capacity and ribcage/diaphragm contributions to ventilation. Anesthesiology. 1987 Feb; 66(2):147-52.
Bickler PE, Dueck R, Prutow RJ. PMID: 3813077.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
-
Blood respiratory properties in pigeons at high altitudes: effects of acclimation. Am J Physiol. 1985 Dec; 249(6 Pt 2):R765-75.
Weinstein Y, Bernstein MH, Bickler PE, Gonzales DV, Samaniego FC, Escobedo MA. PMID: 3934990.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
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Blood acid-base status of an awake heterothermic rodent, Spermophilus tereticaudus. Respir Physiol. 1984 Sep; 57(3):307-16.
Bickler PE. PMID: 6441212.
View in:
PubMed Mentions:
3 Fields:
Translation:
Animals
-
CO2 balance of a heterothermic rodent: comparison of sleep, torpor, and awake states. Am J Physiol. 1984 Jan; 246(1 Pt 2):R49-55.
Bickler PE. PMID: 6421175.
View in:
PubMed Mentions:
11 Fields:
Translation:
Animals