Peter Hwang, PhD

SchoolUCSF School of Medicine
DepartmentBiochemistry and Biophysics
Address600 16th St
San Francisco CA 94158
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Benod C, Villagomez R, Filgueira CS, Hwang P, Leonard PG, Poncet-Montange G, Rajagopalan S, Fletterick RJ, Gustafsson JÅ, Webb P. The human orphan nuclear receptor tailless (TLX, NR2E1) is druggable. PLoS One. 2014; 9(6):e99440. PMID: 24936658; PMCID: PMC4060991.
    2. Capon DJ, Kaneko N, Yoshimori T, Shimada T, Wurm FM, Hwang P, Tong X, Adams SA, Simmons G, Sato TA, Tanaka K. Flexible antibodies with nonprotein hinges. Proc Jpn Acad Ser B Phys Biol Sci. 2011; 87(9):603-16. PMID: 22075761; PMCID: PMC3309923.
    3. Wilbur JD, Hwang P, Ybe JA, Lane M, Sellers BD, Jacobson MP, Fletterick RJ, Brodsky FM. Conformation switching of clathrin light chain regulates clathrin lattice assembly. Dev Cell. 2010 May 18; 18(5):841-8. PMID: 20493816; PMCID: PMC2975025.
    4. Wilbur JD, Hwang P, Brodsky FM, Fletterick RJ. Accommodation of structural rearrangements in the huntingtin-interacting protein 1 coiled-coil domain. Acta Crystallogr D Biol Crystallogr. 2010 Mar; 66(Pt 3):314-8. PMID: 20179344; PMCID: PMC2827350.
    5. Falvo JV, Lin CH, Tsytsykova AV, Hwang P, Thanos D, Goldfeld AE, Maniatis T. A dimer-specific function of the transcription factor NFATp. Proc Natl Acad Sci U S A. 2008 Dec 16; 105(50):19637-42. PMID: 19060202; PMCID: PMC2604938.
    6. Wilbur JD, Chen CY, Manalo V, Hwang P, Fletterick RJ, Brodsky FM. Actin binding by Hip1 (huntingtin-interacting protein 1) and Hip1R (Hip1-related protein) is regulated by clathrin light chain. J Biol Chem. 2008 Nov 21; 283(47):32870-9. PMID: 18790740; PMCID: PMC2583295.
    7. Knuehl C, Chen CY, Manalo V, Hwang P, Ota N, Brodsky FM. Novel binding sites on clathrin and adaptors regulate distinct aspects of coat assembly. Traffic. 2006 Dec; 7(12):1688-700. PMID: 17052248.
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    8. Wilbur JD, Hwang P, Brodsky FM. New faces of the familiar clathrin lattice. Traffic. 2005 Apr; 6(4):346-50. PMID: 15752139.
      View in: PubMed
    9. Wakeham DE, Chen CY, Greene B, Hwang P, Brodsky FM. Clathrin self-assembly involves coordinated weak interactions favorable for cellular regulation. EMBO J. 2003 Oct 01; 22(19):4980-90. PMID: 14517237; PMCID: PMC204494.
    10. Chen CY, Reese ML, Hwang P, Ota N, Agard D, Brodsky FM. Clathrin light and heavy chain interface: alpha-helix binding superhelix loops via critical tryptophans. EMBO J. 2002 Nov 15; 21(22):6072-82. PMID: 12426379; PMCID: PMC137186.
    11. Ybe JA, Wakeham DE, Brodsky FM, Hwang P. Molecular structures of proteins involved in vesicle fusion. Traffic. 2000 Jun; 1(6):474-9. PMID: 11208133.
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    12. Wakeham DE, Ybe JA, Brodsky FM, Hwang P. Molecular structures of proteins involved in vesicle coat formation. Traffic. 2000 May; 1(5):393-8. PMID: 11208125.
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    13. Ybe JA, Brodsky FM, Hofmann K, Lin K, Liu SH, Chen L, Earnest TN, Fletterick RJ, Hwang P. Clathrin self-assembly is mediated by a tandemly repeated superhelix. Nature. 1999 May 27; 399(6734):371-5. PMID: 10360576.
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    14. Butte MJ, Hwang P, Mobley WC, Fletterick RJ. Crystal structure of neurotrophin-3 homodimer shows distinct regions are used to bind its receptors. Biochemistry. 1998 Dec 01; 37(48):16846-52. PMID: 9836577.
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    15. Lin K, Hwang P, Fletterick RJ. Distinct phosphorylation signals converge at the catalytic center in glycogen phosphorylases. Structure. 1997 Nov 15; 5(11):1511-23. PMID: 9384566.
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    16. Lin K, Rath VL, Dai SC, Fletterick RJ, Hwang P. A protein phosphorylation switch at the conserved allosteric site in GP. Science. 1996 Sep 13; 273(5281):1539-42. PMID: 8703213.
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    17. Rath VL, Lin K, Hwang P, Fletterick RJ. The evolution of an allosteric site in phosphorylase. Structure. 1996 Apr 15; 4(4):463-73. PMID: 8740368.
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    18. Lin K, Hwang P, Fletterick RJ. Mechanism of regulation in yeast glycogen phosphorylase. J Biol Chem. 1995 Nov 10; 270(45):26833-9. PMID: 7592925.
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    19. Crerar MM, Karlsson O, Fletterick RJ, Hwang P. Chimeric muscle and brain glycogen phosphorylases define protein domains governing isozyme-specific responses to allosteric activation. J Biol Chem. 1995 Jun 09; 270(23):13748-56. PMID: 7775430.
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    20. Browner MF, Hwang P, Fletterick RJ. Cooperative binding is not required for activation of muscle phosphorylase. Biochemistry. 1992 Nov 24; 31(46):11291-6. PMID: 1445866.
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    21. Rath VL, Hwang P, Fletterick RJ. Purification and crystallization of glycogen phosphorylase from Saccharomyces cerevisiae. J Mol Biol. 1992 Jun 20; 225(4):1027-34. PMID: 1613787.
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    22. Hwang P, Tugendreich S, Fletterick RJ. Molecular analysis of GPH1, the gene encoding glycogen phosphorylase in Saccharomyces cerevisiae. Mol Cell Biol. 1989 Apr; 9(4):1659-66. PMID: 2657401; PMCID: PMC362584.
    23. Newgard CB, Hwang P, Fletterick RJ. The family of glycogen phosphorylases: structure and function. Crit Rev Biochem Mol Biol. 1989; 24(1):69-99. PMID: 2667896.
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    24. Newgard CB, Nakano K, Hwang P, Fletterick RJ. Sequence analysis of the cDNA encoding human liver glycogen phosphorylase reveals tissue-specific codon usage. Proc Natl Acad Sci U S A. 1986 Nov; 83(21):8132-6. PMID: 2877458; PMCID: PMC386881.
    25. Hwang P, Fletterick RJ. Convergent and divergent evolution of regulatory sites in eukaryotic phosphorylases. Nature. 1986 Nov 6-12; 324(6092):80-4. PMID: 3537803.
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    26. Nakano K, Hwang P, Fletterick RJ. Complete cDNA sequence for rabbit muscle glycogen phosphorylase. FEBS Lett. 1986 Aug 18; 204(2):283-7. PMID: 3015680.
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    27. Fletterick RJ, Burke JA, Hwang P, Nakano K, Newgard CB. Structural relationships in glycogen phosphorylases. Ann N Y Acad Sci. 1986; 478:220-32. PMID: 3541750.
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    28. Hwang P, See YP, Vincentini AM, Powers MA, Fletterick RJ, Crerar MM. Comparative sequence analysis of rat, rabbit, and human muscle glycogen phosphorylase cDNAs. Eur J Biochem. 1985 Oct 15; 152(2):267-74. PMID: 3840433.
      View in: PubMed
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