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Exploring antiviral and anti-inflammatory effects of thiol drugs in COVID-19. Am J Physiol Lung Cell Mol Physiol. 2022 09 01; 323(3):L372-L389.
Khanna K, Raymond WW, Jin J, Charbit AR, Gitlin I, Tang M, Werts AD, Barrett EG, Cox JM, Birch SM, Martinelli R, Sperber HS, Franz S, Duff T, Hoffmann M, Healy AM, Oscarson S, Pöhlmann S, Pillai SK, Simmons G, Fahy JV. PMID: 35762590; PMCID: PMC9448286.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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A cytotoxic-skewed immune set point predicts low neutralizing antibody levels after Zika virus infection. Cell Rep. 2022 05 17; 39(7):110815.
McCarthy EE, Odorizzi PM, Lutz E, Smullin CP, Tenvooren I, Stone M, Simmons G, Hunt PW, Feeney ME, Norris PJ, Busch MP, Spitzer MH, Rutishauser RL. PMID: 35584677; PMCID: PMC9151348.
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PubMed Mentions: Fields:
Translation:
HumansCellsPHPublic Health
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Thiol drugs decrease SARS-CoV-2 lung injury in vivo and disrupt SARS-CoV-2 spike complex binding to ACE2 in vitro. bioRxiv. 2021 Nov 11.
Khanna K, Raymond W, Jin J, Charbit AR, Gitlin I, Tang M, Werts AD, Barrett EG, Cox JM, Birch SM, Martinelli R, Sperber HS, Franz S, Pillai S, Healy AM, Duff T, Oscarson S, Hoffmann M, Pöhlmann S, Simmons G, Fahy JV. PMID: 33330868; PMCID: PMC7743076.
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The Specificity of the Persistent IgM Neutralizing Antibody Response in Zika Virus Infections among Individuals with Prior Dengue Virus Exposure. J Clin Microbiol. 2021 07 19; 59(8):e0040021.
Calvert AE, Horiuchi K, Boroughs KL, Ong YT, Anderson KM, Biggerstaff BJ, Stone M, Simmons G, Busch MP, Huang CY. PMID: 33980647; PMCID: PMC8288270.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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Characteristics of High-Titer Convalescent Plasma and Antibody Dynamics After Administration in Patients With Severe Coronavirus Disease 2019. Open Forum Infect Dis. 2021 Aug; 8(8):ofab385.
Bainbridge ED, Hsue PY, Esensten JH, Lynch KL, Hendrickson CM, Doernberg SB, Fung M, Chin-Hong P, Di Germanio C, Norris PJ, Simmons G, Glidden DV, Luetkemeyer AF. PMID: 34405093; PMCID: PMC8344822.
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PubMed Mentions:
3
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Generation of recombinant hyperimmune globulins from diverse B-cell repertoires. Nat Biotechnol. 2021 08; 39(8):989-999.
Keating SM, Mizrahi RA, Adams MS, Asensio MA, Benzie E, Carter KP, Chiang Y, Edgar RC, Gautam BK, Gras A, Leong J, Leong R, Lim YW, Manickam VA, Medina-Cucurella AV, Niedecken AR, Saini J, Simons JF, Spindler MJ, Stadtmiller K, Tinsley B, Wagner EK, Wayham N, Tracy L, Lundberg CV, Büscher D, Terencio JV, Roalfe L, Pearce E, Richardson H, Goldblatt D, Ramjag AT, Carrington CVF, Simmons G, Muench MO, Chamow SM, Monroe B, Olson C, Oguin TH, Lynch H, Jeanfreau R, Mosher RA, Walch MJ, Bartley CR, Ross CA, Meyer EH, Adler AS, Johnson DS. PMID: 33859400; PMCID: PMC8355030.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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Distinct SARS-CoV-2 antibody reactivity patterns in coronavirus convalescent plasma revealed by a coronavirus antigen microarray. Sci Rep. 2021 04 06; 11(1):7554.
Assis R, Jain A, Nakajima R, Jasinskas A, Khan S, Davies H, Corash L, Dumont LJ, Kelly K, Simmons G, Stone M, Di Germanio C, Busch M, Felgner PL. PMID: 33824382; PMCID: PMC8024395.
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PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Selecting COVID-19 convalescent plasma for neutralizing antibody potency using a high-capacity SARS-CoV-2 antibody assay. Transfusion. 2021 04; 61(4):1160-1170.
Goodhue Meyer E, Simmons G, Grebe E, Gannett M, Franz S, Darst O, Di Germanio C, Stone M, Contestable P, Prichard A, Reik R, Vassallo R, Young P, Busch MP, Williamson P, Dumont LJ. PMID: 33554362; PMCID: PMC8013397.
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PubMed Mentions:
20 Fields:
Translation:
HumansCells
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SARS-CoV-2 induces robust germinal center CD4 T follicular helper cell responses in rhesus macaques. Nat Commun. 2021 01 22; 12(1):541.
Shaan Lakshmanappa Y, Elizaldi SR, Roh JW, Schmidt BA, Carroll TD, Weaver KD, Smith JC, Verma A, Deere JD, Dutra J, Stone M, Franz S, Sammak RL, Olstad KJ, Rachel Reader J, Ma ZM, Nguyen NK, Watanabe J, Usachenko J, Immareddy R, Yee JL, Weiskopf D, Sette A, Hartigan-O'Connor D, McSorley SJ, Morrison JH, Tran NK, Simmons G, Busch MP, Kozlowski PA, Van Rompay KKA, Miller CJ, Iyer SS. PMID: 33483492; PMCID: PMC7822826.
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PubMed Mentions:
50 Fields:
Translation:
HumansAnimalsCells
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Analysis of SARS-CoV-2 antibodies in COVID-19 convalescent blood using a coronavirus antigen microarray. Nat Commun. 2021 01 04; 12(1):6.
de Assis RR, Jain A, Nakajima R, Jasinskas A, Felgner J, Obiero JM, Norris PJ, Stone M, Simmons G, Bagri A, Irsch J, Schreiber M, Buser A, Holbro A, Battegay M, Hosimer P, Noesen C, Adenaiye O, Tai S, Hong F, Milton DK, Davies DH, Contestable P, Corash LM, Busch MP, Felgner PL, Khan S. PMID: 33397903; PMCID: PMC7782488.
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PubMed Mentions:
103 Fields:
Translation:
HumansCells
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Bispecific VH/Fab antibodies targeting neutralizing and non-neutralizing Spike epitopes demonstrate enhanced potency against SARS-CoV-2. MAbs. 2021 Jan-Dec; 13(1):1893426.
Lim SA, Gramespacher JA, Pance K, Rettko NJ, Solomon P, Jin J, Lui I, Elledge SK, Liu J, Bracken CJ, Simmons G, Zhou XX, Leung KK, Wells JA. PMID: 33666135; PMCID: PMC7939556.
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PubMed Mentions:
19 Fields:
Translation:
HumansCells
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Antigenicity, stability, and reproducibility of Zika reporter virus particles for long-term applications. PLoS Negl Trop Dis. 2020 11; 14(11):e0008730.
Whitbeck JC, Thomas A, Kadash-Edmondson K, Grinyo-Escuer A, Stafford LJ, Cheng C, Liao GC, Holtsberg FW, Aman MJ, Simmons G, Davidson E, Doranz BJ. PMID: 33206639; PMCID: PMC7673510.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCellsPHPublic Health
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A 3.4-Å cryo-EM structure of the human coronavirus spike trimer computationally derived from vitrified NL63 virus particles. . 2020 Nov 17; 1-15.
Zhang ZK, Li LS, Pintilie PG, Chmielewski CD, Schmid SM, Simmons SG, Jin JJ, Chiu CW. .
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Efficacy of COVID-19 Pathogen Inactivated Convalescent Plasma for Patients with Moderate to Severe Acute COVID-19: A Case Matched Control Study. Blood. 2020 Nov 5; 136(Supplement 1):29-30.
Khanna KN, Weisser WM, Hedstueck HA, Sutter SS, Roesch RS, Battegay BM, Infanti IL, Holbro HA, Busch BM, Simmons SG, Felgner FP, Stone SM, von Goetz vM, de Assis dR, Khan KS, Tsai TJ, Robinson RP, Seftel SD, Bagri BA, Corash CL, Buser BA. .
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Decontamination of SARS-CoV-2 and Other RNA Viruses from N95 Level Meltblown Polypropylene Fabric Using Heat under Different Humidities. ACS Nano. 2020 10 27; 14(10):14017-14025.
Campos RK, Jin J, Rafael GH, Zhao M, Liao L, Simmons G, Chu S, Weaver SC, Chiu W, Cui Y. PMID: 32955847.
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PubMed Mentions:
28 Fields:
Translation:
CellsPHPublic Health
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SARS-CoV-2 seroprevalence and neutralizing activity in donor and patient blood. Nat Commun. 2020 09 17; 11(1):4698.
Ng DL, Goldgof GM, Shy BR, Levine AG, Balcerek J, Bapat SP, Prostko J, Rodgers M, Coller K, Pearce S, Franz S, Du L, Stone M, Pillai SK, Sotomayor-Gonzalez A, Servellita V, Martin CSS, Granados A, Glasner DR, Han LM, Truong K, Akagi N, Nguyen DN, Neumann NM, Qazi D, Hsu E, Gu W, Santos YA, Custer B, Green V, Williamson P, Hills NK, Lu CM, Whitman JD, Stramer SL, Wang C, Reyes K, Hakim JMC, Sujishi K, Alazzeh F, Pham L, Thornborrow E, Oon CY, Miller S, Kurtz T, Simmons G, Hackett J, Busch MP, Chiu CY. PMID: 32943630; PMCID: PMC7499171.
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PubMed Mentions:
124 Fields:
Translation:
HumansCellsPHPublic Health
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Zika virus RNA and IgM persistence in blood compartments and body fluids: a prospective observational study. Lancet Infect Dis. 2020 12; 20(12):1446-1456.
Stone M, Bakkour S, Lanteri MC, Brambilla D, Simmons G, Bruhn R, Kaidarova Z, Lee TH, Orlando Alsina J, Williamson PC, Galel SA, Pate LL, Linnen JM, Kleinman S, Busch MP, NHLBI Recipient Epidemiology Donor Evaluation Study REDS-III Program. PMID: 32673593; PMCID: PMC10029720.
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PubMed Mentions:
24 Fields:
Translation:
HumansCells
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Evolving viral and serological stages of Zika virus RNA-positive blood donors and estimation of incidence of infection during the 2016 Puerto Rican Zika epidemic: an observational cohort study. Lancet Infect Dis. 2020 12; 20(12):1437-1445.
Williamson PC, Biggerstaff BJ, Simmons G, Stone M, Winkelman V, Latoni G, Alsina J, Bakkour S, Newman C, Pate LL, Galel SA, Kleinman S, Busch MP. PMID: 32673594.
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PubMed Mentions:
11 Fields:
Translation:
HumansCellsPHPublic Health
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Seroreactivity against Marburg or related filoviruses in West and Central Africa. Emerg Microbes Infect. 2020; 9(1):124-128.
Steffen I, Lu K, Hoff NA, Mulembakani P, Okitolonda Wemakoy E, Muyembe-Tamfum JJ, Ndembi N, Brennan CA, Hackett J, Switzer WM, Saragosti S, Mbensa GO, Laperche S, Rimoin AW, Simmons G. PMID: 31913767; PMCID: PMC6968259.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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Effects of Chikungunya virus immunity on Mayaro virus disease and epidemic potential. Sci Rep. 2019 12 31; 9(1):20399.
Webb EM, Azar SR, Haller SL, Langsjoen RM, Cuthbert CE, Ramjag AT, Luo H, Plante K, Wang T, Simmons G, Carrington CVF, Weaver SC, Rossi SL, Auguste AJ. PMID: 31892710; PMCID: PMC6938517.
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PubMed Mentions:
31 Fields:
Translation:
AnimalsCellsPHPublic Health
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Guanylate-Binding Proteins 2 and 5 Exert Broad Antiviral Activity by Inhibiting Furin-Mediated Processing of Viral Envelope Proteins. Cell Rep. 2019 05 14; 27(7):2092-2104.e10.
Braun E, Hotter D, Koepke L, Zech F, Groß R, Sparrer KMJ, Müller JA, Pfaller CK, Heusinger E, Wombacher R, Sutter K, Dittmer U, Winkler M, Simmons G, Jakobsen MR, Conzelmann KK, Pöhlmann S, Münch J, Fackler OT, Kirchhoff F, Sauter D. PMID: 31091448.
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PubMed Mentions:
81 Fields:
Translation:
HumansCells
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Serologic Prevalence of Ebola Virus in Equatorial Africa. Emerg Infect Dis. 2019 05; 25(5):911-918.
Steffen I, Lu K, Yamamoto LK, Hoff NA, Mulembakani P, Wemakoy EO, Muyembe-Tamfum JJ, Ndembi N, Brennan CA, Hackett J, Stramer SL, Switzer WM, Saragosti S, Mbensa GO, Laperche S, Rimoin AW, Simmons G. PMID: 31002071; PMCID: PMC6478206.
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PubMed Mentions:
12 Fields:
Translation:
HumansCells
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Antiviral Functions of Monoclonal Antibodies against Chikungunya Virus. Viruses. 2019 03 28; 11(4).
Jin J, Simmons G. PMID: 30925717; PMCID: PMC6520934.
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PubMed Mentions:
26 Fields:
Translation:
HumansAnimalsCells
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Serologic Markers for Ebolavirus Among Healthcare Workers in the Democratic Republic of the Congo. J Infect Dis. 2019 01 29; 219(4):517-525.
Hoff NA, Mukadi P, Doshi RH, Bramble MS, Lu K, Gadoth A, Sinai C, Spencer D, Nicholson BP, Williams R, Mossoko M, Ilunga-Kebela B, Wasiswa J, Okitolonda-Wemakoy E, Alfonso VH, Steffen I, Muyembe-Tamfum JJ, Simmons G, Rimoin AW. PMID: 30239838; PMCID: PMC6350949.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Establishment of an Alphavirus-Specific Neutralization Assay to Distinguish Infections with Different Members of the Semliki Forest complex. Viruses. 2019 01 18; 11(1).
Henss L, Yue C, Kandler J, Faddy HM, Simmons G, Panning M, Lewis-Ximenez LL, Baylis SA, Schnierle BS. PMID: 30669393; PMCID: PMC6356848.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCellsPHPublic Health
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Pan-Filovirus Serum Neutralizing Antibodies in a Subset of Congolese Ebolavirus Infection Survivors. J Infect Dis. 2018 11 05; 218(12):1929-1936.
Bramble MS, Hoff N, Gilchuk P, Mukadi P, Lu K, Doshi RH, Steffen I, Nicholson BP, Lipson A, Vashist N, Sinai C, Spencer D, Olinger G, Wemakoy EO, Illunga BK, Pettitt J, Logue J, Marchand J, Varughese J, Bennett RS, Jahrling P, Cavet G, Serafini T, Ollmann Saphire E, Vilain E, Muyembe-Tamfum JJ, Hensely LE, Simmons G, Crowe JE, Rimoin AW. PMID: 30107445; PMCID: PMC6217721.
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PubMed Mentions:
15 Fields:
Translation:
HumansCells
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Susceptibility of Chikungunya Virus to Inactivation by Heat and Commercially and World Health Organization-Recommended Biocides. J Infect Dis. 2018 09 22; 218(9):1507-1510.
Franz S, Friesland M, Passos V, Todt D, Simmons G, Goffinet C, Steinmann E. PMID: 29917109; PMCID: PMC6151073.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Neutralizing Antibodies Inhibit Chikungunya Virus Budding at the Plasma Membrane. Cell Host Microbe. 2018 09 12; 24(3):417-428.e5.
Jin J, Galaz-Montoya JG, Sherman MB, Sun SY, Goldsmith CS, O'Toole ET, Ackerman L, Carlson LA, Weaver SC, Chiu W, Simmons G. PMID: 30146390; PMCID: PMC6137268.
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PubMed Mentions:
44 Fields:
Translation:
HumansCells
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An attenuated replication-competent chikungunya virus with a fluorescently tagged envelope. PLoS Negl Trop Dis. 2018 07; 12(7):e0006693.
Jin J, Sherman MB, Chafets D, Dinglasan N, Lu K, Lee TH, Carlson LA, Muench MO, Simmons G. PMID: 30063703; PMCID: PMC6086482.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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Arbovirus Diagnostics: From Bad to Worse due to Expanding Dengue Virus Vaccination and Zika Virus Epidemics. Clin Infect Dis. 2018 04 03; 66(8):1181-1183.
Simmons G, Stone M, Busch MP. PMID: 29301009; PMCID: PMC6248677.
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PubMed Mentions:
14 Fields:
Translation:
HumansCellsPHPublic Health
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Ebola Virus Neutralizing Antibodies Detectable in Survivors of theYambuku, Zaire Outbreak 40 Years after Infection. J Infect Dis. 2018 01 04; 217(2):223-231.
Rimoin AW, Lu K, Bramble MS, Steffen I, Doshi RH, Hoff NA, Mukadi P, Nicholson BP, Alfonso VH, Olinger G, Sinai C, Yamamoto LK, Ramirez CM, Okitolonda Wemakoy E, Kebela Illunga B, Pettitt J, Logue J, Bennett RS, Jahrling P, Heymann DL, Piot P, Muyembe-Tamfum JJ, Hensley LE, Simmons G. PMID: 29253164; PMCID: PMC5853670.
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PubMed Mentions:
41 Fields:
Translation:
HumansCellsPHPublic Health
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Distinguishing Secondary Dengue Virus Infection From Zika Virus Infection With Previous Dengue by a Combination of 3 Simple Serological Tests. Clin Infect Dis. 2017 Nov 13; 65(11):1829-1836.
Tsai WY, Youn HH, Brites C, Tsai JJ, Tyson J, Pedroso C, Drexler JF, Stone M, Simmons G, Busch MP, Lanteri M, Stramer SL, Balmaseda A, Harris E, Wang WK. PMID: 29020159; PMCID: PMC5850648.
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PubMed Mentions:
39 Fields:
Translation:
HumansCells
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First cases of Zika virus-infected US blood donors outside states with areas of active transmission. Transfusion. 2017 03; 57(3pt2):770-778.
Williamson PC, Linnen JM, Kessler DA, Shaz BH, Kamel H, Vassallo RR, Winkelman V, Gao K, Ziermann R, Menezes J, Thomas S, Holmberg JA, Bakkour S, Stone M, Lu K, Simmons G, Busch MP. PMID: 28229475.
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PubMed Mentions:
23 Fields:
Translation:
HumansCells
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Zika Virus Tissue and Blood Compartmentalization in Acute Infection of Rhesus Macaques. PLoS One. 2017; 12(1):e0171148.
Coffey LL, Pesavento PA, Keesler RI, Singapuri A, Watanabe J, Watanabe R, Yee J, Bliss-Moreau E, Cruzen C, Christe KL, Reader JR, von Morgenland W, Gibbons AM, Allen AM, Linnen J, Gao K, Delwart E, Simmons G, Stone M, Lanteri M, Bakkour S, Busch M, Morrison J, Van Rompay KK. PMID: 28141843; PMCID: PMC5283740.
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PubMed Mentions:
66 Fields:
Translation:
AnimalsCells
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Higher Serum Alanine Transaminase Levels in Male Urokinase-Type Plasminogen Activator-Transgenic Mice Are Associated With Improved Engraftment of Hepatocytes but not Liver Sinusoidal Endothelial Cells. Cell Med. 2017; 9(3):117-125.
Fomin ME, Beyer AI, Publicover J, Lu K, Bakkour S, Simmons G, Muench MO. PMID: 28713641; PMCID: PMC5509021.
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PubMed Mentions:
2
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High Incidence of Chikungunya Virus and Frequency of Viremic Blood Donations during Epidemic, Puerto Rico, USA, 2014. Emerg Infect Dis. 2016 07; 22(7):1221-8.
Simmons G, Brès V, Lu K, Liss NM, Brambilla DJ, Ryff KR, Bruhn R, Velez E, Ocampo D, Linnen JM, Latoni G, Petersen LR, Williamson PC, Busch MP. PMID: 27070192; PMCID: PMC4918147.
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PubMed Mentions:
55 Fields:
Translation:
HumansCellsPHPublic Health
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Inhibitory Antibodies Targeting Emerging Viruses: Advancements and Mechanisms. Clin Vaccine Immunol. 2016 07; 23(7):535-9.
Jin J, Simmons G. PMID: 27226280; PMCID: PMC4933769.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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Duration of Dengue Viremia in Blood Donors and Relationships Between Donor Viremia, Infection Incidence and Clinical Case Reports During a Large Epidemic. J Infect Dis. 2016 07 01; 214(1):49-54.
Busch MP, Sabino EC, Brambilla D, Lopes ME, Capuani L, Chowdhury D, McClure C, Linnen JM, Prince H, Simmons G, Lee TH, Kleinman S, Custer B, International Component of the NHLBI Recipient Epidemiology and Donor Evaluation Study-III (REDS-III. PMID: 27302934; PMCID: PMC4907419.
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PubMed Mentions:
24 Fields:
Translation:
HumansAnimalsCellsPHPublic Health
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Pseudotyping Viral Vectors With Emerging Virus Envelope Proteins. Curr Gene Ther. 2016; 16(1):47-55.
Steffen I, Simmons G. PMID: 26785737.
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PubMed Mentions:
20 Fields:
Translation:
Cells
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Neutralizing Monoclonal Antibodies Block Chikungunya Virus Entry and Release by Targeting an Epitope Critical to Viral Pathogenesis. Cell Rep. 2015 Dec 22; 13(11):2553-2564.
Jin J, Liss NM, Chen DH, Liao M, Fox JM, Shimak RM, Fong RH, Chafets D, Bakkour S, Keating S, Fomin ME, Muench MO, Sherman MB, Doranz BJ, Diamond MS, Simmons G. PMID: 26686638; PMCID: PMC4720387.
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PubMed Mentions:
62 Fields:
Translation:
HumansAnimalsCells
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Broadly Neutralizing Alphavirus Antibodies Bind an Epitope on E2 and Inhibit Entry and Egress. Cell. 2015 Nov 19; 163(5):1095-1107.
Fox JM, Long F, Edeling MA, Lin H, van Duijl-Richter MKS, Fong RH, Kahle KM, Smit JM, Jin J, Simmons G, Doranz BJ, Crowe JE, Fremont DH, Rossmann MG, Diamond MS. PMID: 26553503; PMCID: PMC4659373.
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PubMed Mentions:
119 Fields:
Translation:
HumansAnimalsCells
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Coronaviruses. eLS. 2015 Jul 15; 1-9.
Steffen SI, Simmons SG. .
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Interferon-Induced Transmembrane Protein-Mediated Inhibition of Host Cell Entry of Ebolaviruses. J Infect Dis. 2015 Oct 01; 212 Suppl 2:S210-8.
Wrensch F, Karsten CB, Gnirß K, Hoffmann M, Lu K, Takada A, Winkler M, Simmons G, Pöhlmann S. PMID: 26034199; PMCID: PMC4564551.
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PubMed Mentions:
50 Fields:
Translation:
HumansCells
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EMERGING RHABDOVIRUSES. Biology and Pathogenesis of Rhabdo- and Filoviruses. 2015 Mar 1; 311-334.
Steffen SI, Simmons SG. .
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Protease inhibitors targeting coronavirus and filovirus entry. Antiviral Res. 2015 Apr; 116:76-84.
Zhou Y, Vedantham P, Lu K, Agudelo J, Carrion R, Nunneley JW, Barnard D, Pöhlmann S, McKerrow JH, Renslo AR, Simmons G. PMID: 25666761; PMCID: PMC4774534.
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PubMed Mentions:
342 Fields:
Translation:
HumansAnimalsCells
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Human keratinocytes restrict chikungunya virus replication at a post-fusion step. Virology. 2015 Feb; 476:1-10.
Bernard E, Hamel R, Neyret A, Ekchariyawat P, Molès JP, Simmons G, Chazal N, Desprès P, Missé D, Briant L. PMID: 25496825.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
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Exposure of epitope residues on the outer face of the chikungunya virus envelope trimer determines antibody neutralizing efficacy. J Virol. 2014 Dec; 88(24):14364-79.
Fong RH, Banik SS, Mattia K, Barnes T, Tucker D, Liss N, Lu K, Selvarajah S, Srinivasan S, Mabila M, Miller A, Muench MO, Michault A, Rucker JB, Paes C, Simmons G, Kahle KM, Doranz BJ. PMID: 25275138; PMCID: PMC4249124.
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PubMed Mentions:
49 Fields:
Translation:
HumansAnimalsCells
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Proteolytic activation of the SARS-coronavirus spike protein: cutting enzymes at the cutting edge of antiviral research. Antiviral Res. 2013 Dec; 100(3):605-14.
Simmons G, Zmora P, Gierer S, Heurich A, Pöhlmann S. PMID: 24121034; PMCID: PMC3889862.
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PubMed Mentions:
225 Fields:
Translation:
HumansCells
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A neutralizing monoclonal antibody targeting the acid-sensitive region in chikungunya virus E2 protects from disease. PLoS Negl Trop Dis. 2013; 7(9):e2423.
Selvarajah S, Sexton NR, Kahle KM, Fong RH, Mattia KA, Gardner J, Lu K, Liss NM, Salvador B, Tucker DF, Barnes T, Mabila M, Zhou X, Rossini G, Rucker JB, Sanders DA, Suhrbier A, Sambri V, Michault A, Muench MO, Doranz BJ, Simmons G. PMID: 24069479; PMCID: PMC3772074.
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PubMed Mentions:
59 Fields:
Translation:
HumansAnimalsCells
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Characterization of the Bas-Congo virus glycoprotein and its function in pseudotyped viruses. J Virol. 2013 Sep; 87(17):9558-68.
Steffen I, Liss NM, Schneider BS, Fair JN, Chiu CY, Simmons G. PMID: 23785218; PMCID: PMC3754090.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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The spike protein of the emerging betacoronavirus EMC uses a novel coronavirus receptor for entry, can be activated by TMPRSS2, and is targeted by neutralizing antibodies. J Virol. 2013 May; 87(10):5502-11.
Gierer S, Bertram S, Kaup F, Wrensch F, Heurich A, Krämer-Kühl A, Welsch K, Winkler M, Meyer B, Drosten C, Dittmer U, von Hahn T, Simmons G, Hofmann H, Pöhlmann S. PMID: 23468491; PMCID: PMC3648152.
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PubMed Mentions:
227 Fields:
Translation:
HumansCells
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Filoviruses utilize glycosaminoglycans for their attachment to target cells. J Virol. 2013 Mar; 87(6):3295-304.
Salvador B, Sexton NR, Carrion R, Nunneley J, Patterson JL, Steffen I, Lu K, Muench MO, Lembo D, Simmons G. PMID: 23302881; PMCID: PMC3592117.
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PubMed Mentions:
38 Fields:
Translation:
HumansAnimalsCells
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Filovirus entry. Adv Exp Med Biol. 2013; 790:83-94.
Simmons G. PMID: 23884587; PMCID: PMC7114988.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Development of novel entry inhibitors targeting emerging viruses. Expert Rev Anti Infect Ther. 2012 Oct; 10(10):1129-38.
Zhou Y, Simmons G. PMID: 23199399; PMCID: PMC3587779.
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PubMed Mentions:
31 Fields:
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A novel rhabdovirus associated with acute hemorrhagic fever in central Africa. PLoS Pathog. 2012 Sep; 8(9):e1002924.
Grard G, Fair JN, Lee D, Slikas E, Steffen I, Muyembe JJ, Sittler T, Veeraraghavan N, Ruby JG, Wang C, Makuwa M, Mulembakani P, Tesh RB, Mazet J, Rimoin AW, Taylor T, Schneider BS, Simmons G, Delwart E, Wolfe ND, Chiu CY, Leroy EM. PMID: 23028323; PMCID: PMC3460624.
-
In-depth investigation of archival and prospectively collected samples reveals no evidence for XMRV infection in prostate cancer. PLoS One. 2012; 7(9):e44954.
Lee D, Das Gupta J, Gaughan C, Steffen I, Tang N, Luk KC, Qiu X, Urisman A, Fischer N, Molinaro R, Broz M, Schochetman G, Klein EA, Ganem D, Derisi JL, Simmons G, Hackett J, Silverman RH, Chiu CY. PMID: 23028701; PMCID: PMC3445615.
View in:
PubMed Mentions:
27 Fields:
Translation:
HumansAnimalsCells
-
Emerging infectious agents and the nation's blood supply: responding to potential threats in the 21st century. Transfusion. 2013 Feb; 53(2):438-54.
Glynn SA, Busch MP, Dodd RY, Katz LM, Stramer SL, Klein HG, Simmons G, Kleinman SH, Shurin SB, NHLBI Emerging Infectious Disease Task Force convened November 7, 2011. PMID: 22690676; PMCID: PMC3644861.
View in:
PubMed Mentions:
18 Fields:
Translation:
HumansAnimalsPHPublic Health
-
Detection of host immune responses in acute phase sera of spontaneous resolution versus persistent hepatitis C virus infection. J Gen Virol. 2012 Aug; 93(Pt 8):1673-1679.
Selvarajah S, Keating S, Heitman J, Lu K, Simmons G, Norris PJ, Operskalski E, Mosley JW, Busch MP. PMID: 22535775; PMCID: PMC3541758.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCells
-
Development and application of a high-throughput microneutralization assay: lack of xenotropic murine leukemia virus-related virus and/or murine leukemia virus detection in blood donors. Transfusion. 2012 Feb; 52(2):332-42.
Zhou Y, Steffen I, Montalvo L, Lee TH, Zemel R, Switzer WM, Tang S, Jia H, Heneine W, Winkelman V, Tailor CS, Ikeda Y, Simmons G. PMID: 22239212; PMCID: PMC3299481.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
-
No evidence of murine leukemia virus-related viruses in live attenuated human vaccines. PLoS One. 2011; 6(12):e29223.
Switzer WM, Zheng H, Simmons G, Zhou Y, Tang S, Shankar A, Kapusinszky B, Delwart EL, Heneine W. PMID: 22216219; PMCID: PMC3245253.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCellsPHPublic Health
-
No evidence for XMRV nucleic acids, infectious virus or anti-XMRV antibodies in Canadian patients with chronic fatigue syndrome. PLoS One. 2011; 6(11):e27870.
Steffen I, Tyrrell DL, Stein E, Montalvo L, Lee TH, Zhou Y, Lu K, Switzer WM, Tang S, Jia H, Hockman D, Santer DM, Logan M, Landi A, Law J, Houghton M, Simmons G. PMID: 22114717; PMCID: PMC3219700.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCells
-
Development of sensitive single-round pol or env RT-PCR assays to screen for XMRV in multiple sample types. J Virol Methods. 2012 Jan; 179(1):127-34.
Tang N, Frank A, Leckie G, Hackett J, Simmons G, Busch M, Abravaya K. PMID: 22057262; PMCID: PMC3573700.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCellsPHPublic Health
-
Cleavage and activation of the severe acute respiratory syndrome coronavirus spike protein by human airway trypsin-like protease. J Virol. 2011 Dec; 85(24):13363-72.
Bertram S, Glowacka I, Müller MA, Lavender H, Gnirss K, Nehlmeier I, Niemeyer D, He Y, Simmons G, Drosten C, Soilleux EJ, Jahn O, Steffen I, Pöhlmann S. PMID: 21994442; PMCID: PMC3233180.
View in:
PubMed Mentions:
189 Fields:
Translation:
HumansCells
-
Failure to confirm XMRV/MLVs in the blood of patients with chronic fatigue syndrome: a multi-laboratory study. Science. 2011 Nov 11; 334(6057):814-7.
Simmons G, Glynn SA, Komaroff AL, Mikovits JA, Tobler LH, Hackett J, Tang N, Switzer WM, Heneine W, Hewlett IK, Zhao J, Lo SC, Alter HJ, Linnen JM, Gao K, Coffin JM, Kearney MF, Ruscetti FW, Pfost MA, Bethel J, Kleinman S, Holmberg JA, Busch MP, Blood XMRV Scientific Research Working Group (SRWG). PMID: 21940862; PMCID: PMC3299483.
View in:
PubMed Mentions:
50 Fields:
Translation:
HumansCells
-
Inhibitors of SARS-CoV entry--identification using an internally-controlled dual envelope pseudovirion assay. Antiviral Res. 2011 Nov; 92(2):187-94.
Zhou Y, Agudelo J, Lu K, Goetz DH, Hansell E, Chen YT, Roush WR, McKerrow J, Craik CS, Amberg SM, Simmons G. PMID: 21820471; PMCID: PMC3205982.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansCells
-
No evidence of murine-like gammaretroviruses in CFS patients previously identified as XMRV-infected. Science. 2011 Jul 01; 333(6038):94-7.
Knox K, Carrigan D, Simmons G, Teque F, Zhou Y, Hackett J, Qiu X, Luk KC, Schochetman G, Knox A, Kogelnik AM, Levy JA. PMID: 21628393.
View in:
PubMed Mentions:
54 Fields:
Translation:
HumansCellsPHPublic Health
-
Different host cell proteases activate the SARS-coronavirus spike-protein for cell-cell and virus-cell fusion. Virology. 2011 May 10; 413(2):265-74.
Simmons G, Bertram S, Glowacka I, Steffen I, Chaipan C, Agudelo J, Lu K, Rennekamp AJ, Hofmann H, Bates P, Pöhlmann S. PMID: 21435673; PMCID: PMC3086175.
View in:
PubMed Mentions:
84 Fields:
Translation:
HumansCells
-
The Blood Xenotropic Murine Leukemia Virus-Related Virus Scientific Research Working Group: mission, progress, and plans. Transfusion. 2011 Mar; 51(3):643-53.
Simmons G, Glynn SA, Holmberg JA, Coffin JM, Hewlett IK, Lo SC, Mikovits JA, Switzer WM, Linnen JM, Busch MP, Blood XMRV Scientific Research Working Group. PMID: 21366602; PMCID: PMC3071162.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansCellsPHPublic Health
-
Inhibition of severe acute respiratory syndrome coronavirus replication in a lethal SARS-CoV BALB/c mouse model by stinging nettle lectin, Urtica dioica agglutinin. Antiviral Res. 2011 Apr; 90(1):22-32.
Kumaki Y, Wandersee MK, Smith AJ, Zhou Y, Simmons G, Nelson NM, Bailey KW, Vest ZG, Li JK, Chan PK, Smee DF, Barnard DL. PMID: 21338626; PMCID: PMC3085190.
View in:
PubMed Mentions:
47 Fields:
Translation:
AnimalsCells
-
Flexible antibodies with nonprotein hinges. Proc Jpn Acad Ser B Phys Biol Sci. 2011; 87(9):603-16.
Capon DJ, Kaneko N, Yoshimori T, Shimada T, Wurm FM, Hwang PK, Tong X, Adams SA, Simmons G, Sato TA, Tanaka K. PMID: 22075761; PMCID: PMC3309923.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCells
-
Host genetic basis for hepatitis C virus clearance: a role for blood collection centers. Curr Opin Hematol. 2010 Nov; 17(6):550-7.
Selvarajah S, Tobler LH, Simmons G, Busch MP. PMID: 20729732; PMCID: PMC3069808.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCells
-
Absence of evidence of xenotropic murine leukemia virus-related virus infection in persons with chronic fatigue syndrome and healthy controls in the United States. Retrovirology. 2010 Jul 01; 7:57.
Switzer WM, Jia H, Hohn O, Zheng H, Tang S, Shankar A, Bannert N, Simmons G, Hendry RM, Falkenberg VR, Reeves WC, Heneine W. PMID: 20594299; PMCID: PMC2908559.
View in:
PubMed Mentions:
81 Fields:
Translation:
HumansCells
-
A single asparagine-linked glycosylation site of the severe acute respiratory syndrome coronavirus spike glycoprotein facilitates inhibition by mannose-binding lectin through multiple mechanisms. J Virol. 2010 Sep; 84(17):8753-64.
Zhou Y, Lu K, Pfefferle S, Bertram S, Glowacka I, Drosten C, Pöhlmann S, Simmons G. PMID: 20573835; PMCID: PMC2919028.
View in:
PubMed Mentions:
103 Fields:
Translation:
HumansCells
-
Incorporation of podoplanin into HIV released from HEK-293T cells, but not PBMC, is required for efficient binding to the attachment factor CLEC-2. Retrovirology. 2010 May 19; 7:47.
Chaipan C, Steffen I, Tsegaye TS, Bertram S, Glowacka I, Kato Y, Schmökel J, Münch J, Simmons G, Gerardy-Schahn R, Pöhlmann S. PMID: 20482880; PMCID: PMC2885308.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansCells
-
Differential downregulation of ACE2 by the spike proteins of severe acute respiratory syndrome coronavirus and human coronavirus NL63. J Virol. 2010 Jan; 84(2):1198-205.
Glowacka I, Bertram S, Herzog P, Pfefferle S, Steffen I, Muench MO, Simmons G, Hofmann H, Kuri T, Weber F, Eichler J, Drosten C, Pöhlmann S. PMID: 19864379; PMCID: PMC2798380.
View in:
PubMed Mentions:
311 Fields:
Translation:
HumansAnimalsCells
-
Characterization of Chikungunya pseudotyped viruses: Identification of refractory cell lines and demonstration of cellular tropism differences mediated by mutations in E1 glycoprotein. Virology. 2009 Oct 10; 393(1):33-41.
Salvador B, Zhou Y, Michault A, Muench MO, Simmons G. PMID: 19692105; PMCID: PMC2760448.
View in:
PubMed Mentions:
42 Fields:
Translation:
HumansAnimalsCells
-
Proteolysis of the Ebola virus glycoproteins enhances virus binding and infectivity. J Virol. 2007 Dec; 81(24):13378-84.
Kaletsky RL, Simmons G, Bates P. PMID: 17928356; PMCID: PMC2168880.
View in:
PubMed Mentions:
112 Fields:
Translation:
HumansAnimalsCells
-
Highly conserved regions within the spike proteins of human coronaviruses 229E and NL63 determine recognition of their respective cellular receptors. J Virol. 2006 Sep; 80(17):8639-52.
Hofmann H, Simmons G, Rennekamp AJ, Chaipan C, Gramberg T, Heck E, Geier M, Wegele A, Marzi A, Bates P, Pöhlmann S. PMID: 16912312; PMCID: PMC1563880.
View in:
PubMed Mentions:
73 Fields:
Translation:
HumansAnimalsCells
-
The signal peptide of the ebolavirus glycoprotein influences interaction with the cellular lectins DC-SIGN and DC-SIGNR. J Virol. 2006 Jul; 80(13):6305-17.
Marzi A, Akhavan A, Simmons G, Gramberg T, Hofmann H, Bates P, Lingappa VR, Pöhlmann S. PMID: 16775318; PMCID: PMC1488929.
View in:
PubMed Mentions:
37 Fields:
Translation:
HumansCells
-
Endosomal proteolysis by cathepsins is necessary for murine coronavirus mouse hepatitis virus type 2 spike-mediated entry. J Virol. 2006 Jun; 80(12):5768-76.
Qiu Z, Hingley ST, Simmons G, Yu C, Das Sarma J, Bates P, Weiss SR. PMID: 16731916; PMCID: PMC1472567.
View in:
PubMed Mentions:
102 Fields:
Translation:
AnimalsCells
-
Proteolysis of SARS-associated coronavirus spike glycoprotein. Adv Exp Med Biol. 2006; 581:235-40.
Simmons G, Rennekamp AJ, Bates P. PMID: 17037535; PMCID: PMC7123722.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCells
-
Expanded tropism and altered activation of a retroviral glycoprotein resistant to an entry inhibitor peptide. J Virol. 2006 Jan; 80(1):353-9.
Amberg SM, Netter RC, Simmons G, Bates P. PMID: 16352560; PMCID: PMC1317511.
View in:
PubMed Mentions:
10 Fields:
Translation:
Cells
-
Inhibitors of cathepsin L prevent severe acute respiratory syndrome coronavirus entry. Proc Natl Acad Sci U S A. 2005 Aug 16; 102(33):11876-81.
Simmons G, Gosalia DN, Rennekamp AJ, Reeves JD, Diamond SL, Bates P. PMID: 16081529; PMCID: PMC1188015.
View in:
PubMed Mentions:
665 Fields:
Translation:
HumansCells
-
Longitudinally profiling neutralizing antibody response to SARS coronavirus with pseudotypes. Emerg Infect Dis. 2005 Mar; 11(3):411-6.
Temperton NJ, Chan PK, Simmons G, Zambon MC, Tedder RS, Takeuchi Y, Weiss RA. PMID: 15757556; PMCID: PMC3298259.
View in:
PubMed Mentions:
102 Fields:
Translation:
HumansCells
-
DC-SIGN and DC-SIGNR interact with the glycoprotein of Marburg virus and the S protein of severe acute respiratory syndrome coronavirus. J Virol. 2004 Nov; 78(21):12090-5.
Marzi A, Gramberg T, Simmons G, Möller P, Rennekamp AJ, Krumbiegel M, Geier M, Eisemann J, Turza N, Saunier B, Steinkasserer A, Becker S, Bates P, Hofmann H, Pöhlmann S. PMID: 15479853; PMCID: PMC523257.
View in:
PubMed Mentions:
225 Fields:
Translation:
Cells
-
Biological analysis of human immunodeficiency virus type 1 R5 envelopes amplified from brain and lymph node tissues of AIDS patients with neuropathology reveals two distinct tropism phenotypes and identifies envelopes in the brain that confer an enhanced tropism and fusigenicity for macrophages. J Virol. 2004 Jul; 78(13):6915-26.
Peters PJ, Bhattacharya J, Hibbitts S, Dittmar MT, Simmons G, Bell J, Simmonds P, Clapham PR. PMID: 15194768; PMCID: PMC421670.
View in:
PubMed Mentions:
128 Fields:
Translation:
HumansCells
-
Characterization of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) spike glycoprotein-mediated viral entry. Proc Natl Acad Sci U S A. 2004 Mar 23; 101(12):4240-5.
Simmons G, Reeves JD, Rennekamp AJ, Amberg SM, Piefer AJ, Bates P. PMID: 15010527; PMCID: PMC384725.
View in:
PubMed Mentions:
337 Fields:
Translation:
HumansCells
-
Identification of murine T-cell epitopes in Ebola virus nucleoprotein. Virology. 2004 Jan 05; 318(1):224-30.
Simmons G, Lee A, Rennekamp AJ, Fan X, Bates P, Shen H. PMID: 14972550.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCellsPHPublic Health
-
Folate receptor alpha and caveolae are not required for Ebola virus glycoprotein-mediated viral infection. J Virol. 2003 Dec; 77(24):13433-8.
Simmons G, Rennekamp AJ, Chai N, Vandenberghe LH, Riley JL, Bates P. PMID: 14645601; PMCID: PMC296046.
View in:
PubMed Mentions:
66 Fields:
Translation:
HumansAnimalsCells
-
DC-SIGN and DC-SIGNR bind ebola glycoproteins and enhance infection of macrophages and endothelial cells. Virology. 2003 Jan 05; 305(1):115-23.
Simmons G, Reeves JD, Grogan CC, Vandenberghe LH, Baribaud F, Whitbeck JC, Burke E, Buchmeier MJ, Soilleux EJ, Riley JL, Doms RW, Bates P, Pöhlmann S. PMID: 12504546.
View in:
PubMed Mentions:
199 Fields:
Translation:
HumansCells
-
Differential N-linked glycosylation of human immunodeficiency virus and Ebola virus envelope glycoproteins modulates interactions with DC-SIGN and DC-SIGNR. J Virol. 2003 Jan; 77(2):1337-46.
Lin G, Simmons G, Pöhlmann S, Baribaud F, Ni H, Leslie GJ, Haggarty BS, Bates P, Weissman D, Hoxie JA, Doms RW. PMID: 12502850; PMCID: PMC140807.
View in:
PubMed Mentions:
134 Fields:
Translation:
HumansCells
-
Ebola virus glycoproteins induce global surface protein down-modulation and loss of cell adherence. J Virol. 2002 Mar; 76(5):2518-28.
Simmons G, Wool-Lewis RJ, Baribaud F, Netter RC, Bates P. PMID: 11836430; PMCID: PMC153797.
View in:
PubMed Mentions:
118 Fields:
Translation:
HumansAnimalsCells
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Evidence for a post-entry barrier to R5 HIV-1 infection of CD4 memory T cells. AIDS. 2001 Sep 07; 15(13):1613-26.
Vyakarnam A, Eyeson J, Teo I, Zuckerman M, Babaahmady K, Schuitemaker H, Shaunak S, Rostron T, Rowland-Jones S, Simmons G, Clapham P. PMID: 11546935.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansCells
-
A chimeric MIP-1alpha/RANTES protein demonstrates the use of different regions of the RANTES protein to bind and activate its receptors. J Leukoc Biol. 2001 Jun; 69(6):977-85.
Blanpain C, Buser R, Power CA, Edgerton M, Buchanan C, Mack M, Simmons G, Clapham PR, Parmentier M, Proudfoot AE. PMID: 11404385.
View in:
PubMed Mentions:
19 Fields:
Translation:
Cells
-
Phylogenetic analysis of multiple heterosexual transmission events involving subtype b of HIV type 1. AIDS Res Hum Retroviruses. 2001 May 20; 17(8):689-95.
Hayman A, Moss T, Simmons G, Arnold C, Holmes EC, Naylor-Adamson L, Hawkswell J, Allen K, Radford J, Nguyen-Van-Tam J, Balfe P. PMID: 11429109.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCellsPHPublic Health
-
T-cell line adaptation of human immunodeficiency virus type 1 strain SF162: effects on envelope, vpu and macrophage-tropism. J Gen Virol. 2000 Dec; 81(Pt 12):2899-2904.
Dejucq N, Simmons G, Clapham PR. PMID: 11086121.
View in:
PubMed Mentions:
18 Fields:
Translation:
HumansCells
-
Co-receptor use by HIV and inhibition of HIV infection by chemokine receptor ligands. Immunol Rev. 2000 Oct; 177:112-26.
Simmons G, Reeves JD, Hibbitts S, Stine JT, Gray PW, Proudfoot AE, Clapham PR. PMID: 11138769.
View in:
PubMed Mentions:
38 Fields:
Translation:
HumansCells
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A small molecule antagonist of chemokine receptors CCR1 and CCR3. Potent inhibition of eosinophil function and CCR3-mediated HIV-1 entry. J Biol Chem. 2000 Aug 25; 275(34):25985-92.
Sabroe I, Peck MJ, Van Keulen BJ, Jorritsma A, Simmons G, Clapham PR, Williams TJ, Pease JE. PMID: 10854442.
View in:
PubMed Mentions:
38 Fields:
Translation:
HumansAnimalsCells
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Differential activation of CC chemokine receptors by AOP-RANTES. J Biol Chem. 2000 Mar 17; 275(11):7787-94.
Elsner J, Mack M, Brühl H, Dulkys Y, Kimmig D, Simmons G, Clapham PR, Schlöndorff D, Kapp A, Wells TN, Proudfoot AE. PMID: 10713092.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansCells
-
KSHV-encoded CC chemokine vMIP-III is a CCR4 agonist, stimulates angiogenesis, and selectively chemoattracts TH2 cells. Blood. 2000 Feb 15; 95(4):1151-7.
Stine JT, Wood C, Hill M, Epp A, Raport CJ, Schweickart VL, Endo Y, Sasaki T, Simmons G, Boshoff C, Clapham P, Chang Y, Moore P, Gray PW, Chantry D. PMID: 10666184.
View in:
PubMed Mentions:
68 Fields:
Translation:
HumansAnimalsCells
-
Chemokine inhibition of HIV infection. Methods Mol Biol. 2000; 138:209-22.
Reeves JD, Simmons G. PMID: 10840761.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Primary human immunodeficiency virus type 2 (HIV-2) isolates infect CD4-negative cells via CCR5 and CXCR4: comparison with HIV-1 and simian immunodeficiency virus and relevance to cell tropism in vivo. J Virol. 1999 Sep; 73(9):7795-804.
Reeves JD, Hibbitts S, Simmons G, McKnight A, Azevedo-Pereira JM, Moniz-Pereira J, Clapham PR. PMID: 10438870; PMCID: PMC104307.
View in:
PubMed Mentions:
57 Fields:
Translation:
HumansAnimalsCells
-
Expanded tropism of primary human immunodeficiency virus type 1 R5 strains to CD4(+) T-cell lines determined by the capacity to exploit low concentrations of CCR5. J Virol. 1999 Sep; 73(9):7842-7.
Dejucq N, Simmons G, Clapham PR. PMID: 10438877; PMCID: PMC104314.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansCells
-
Coreceptor ligand inhibition of fetal brain cell infection by HIV type 1. AIDS Res Hum Retroviruses. 1999 Jul 20; 15(11):989-1000.
Hibbitts S, Reeves JD, Simmons G, Gray PW, Epstein LG, Schols D, de Clercq E, Wells TN, Proudfoot AE, Clapham PR. PMID: 10445811.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCells
-
HIV coreceptors, cell tropism and inhibition by chemokine receptor ligands. Mol Membr Biol. 1999 Jan-Mar; 16(1):49-55.
Clapham PR, Reeves JD, Simmons G, Dejucq N, Hibbitts S, McKnight A. PMID: 10332737.
View in:
PubMed Mentions:
20 Fields:
Translation:
Humans
-
CXCR4 as a functional coreceptor for human immunodeficiency virus type 1 infection of primary macrophages. J Virol. 1998 Oct; 72(10):8453-7.
Simmons G, Reeves JD, McKnight A, Dejucq N, Hibbitts S, Power CA, Aarons E, Schols D, De Clercq E, Proudfoot AE, Clapham PR. PMID: 9733901; PMCID: PMC110244.
View in:
PubMed Mentions:
62 Fields:
Translation:
HumansCells
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Aminooxypentane-RANTES induces CCR5 internalization but inhibits recycling: a novel inhibitory mechanism of HIV infectivity. J Exp Med. 1998 Apr 20; 187(8):1215-24.
Mack M, Luckow B, Nelson PJ, Cihak J, Simmons G, Clapham PR, Signoret N, Marsh M, Stangassinger M, Borlat F, Wells TN, Schlöndorff D, Proudfoot AE. PMID: 9547333; PMCID: PMC2212227.
View in:
PubMed Mentions:
119 Fields:
Translation:
HumansAnimalsCells
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Langerhans cell tropism of human immunodeficiency virus type 1 subtype A through F isolates derived from different transmission groups. J Virol. 1997 Oct; 71(10):8008-13.
Dittmar MT, Simmons G, Hibbitts S, O'Hare M, Louisirirotchanakul S, Beddows S, Weber J, Clapham PR, Weiss RA. PMID: 9311896; PMCID: PMC192163.
View in:
PubMed Mentions:
20 Fields:
Translation:
HumansCells
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A broad-spectrum chemokine antagonist encoded by Kaposi's sarcoma-associated herpesvirus. Science. 1997 Sep 12; 277(5332):1656-9.
Kledal TN, Rosenkilde MM, Coulin F, Simmons G, Johnsen AH, Alouani S, Power CA, Lüttichau HR, Gerstoft J, Clapham PR, Clark-Lewis I, Wells TN, Schwartz TW. PMID: 9287217.
View in:
PubMed Mentions:
134 Fields:
Translation:
HumansAnimalsCells
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Biological characterization of human immunodeficiency virus type 1 clones derived from different organs of an AIDS patient by long-range PCR. J Virol. 1997 Jul; 71(7):5140-7.
Dittmar MT, Simmons G, Donaldson Y, Simmonds P, Clapham PR, Schulz TF, Weiss RA. PMID: 9188581; PMCID: PMC191749.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCells
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Multiple extracellular domains of CCR-5 contribute to human immunodeficiency virus type 1 entry and fusion. J Virol. 1997 Jul; 71(7):5003-11.
Picard L, Simmons G, Power CA, Meyer A, Weiss RA, Clapham PR. PMID: 9188565; PMCID: PMC191733.
View in:
PubMed Mentions:
46 Fields:
Translation:
HumansAnimalsCells
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CD4-independent infection by HIV-2 (ROD/B): use of the 7-transmembrane receptors CXCR-4, CCR-3, and V28 for entry. Virology. 1997 Apr 28; 231(1):130-4.
Reeves JD, McKnight A, Potempa S, Simmons G, Gray PW, Power CA, Wells T, Weiss RA, Talbot SJ. PMID: 9143311.
View in:
PubMed Mentions:
47 Fields:
Translation:
HumansAnimalsCells
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Potent inhibition of HIV-1 infectivity in macrophages and lymphocytes by a novel CCR5 antagonist. Science. 1997 Apr 11; 276(5310):276-9.
Simmons G, Clapham PR, Picard L, Offord RE, Rosenkilde MM, Schwartz TW, Buser R, Wells TN, Proudfoot AE. PMID: 9092481.
View in:
PubMed Mentions:
154 Fields:
Translation:
HumansAnimalsCells
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HIV-1 tropism and co-receptor use. Nature. 1997 Feb 06; 385(6616):495-6.
Dittmar MT, McKnight A, Simmons G, Clapham PR, Weiss RA, Simmonds P. PMID: 9020356.
View in:
PubMed Mentions:
43 Fields:
Translation:
HumansAnimalsCells
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Inhibition of human immunodeficiency virus fusion by a monoclonal antibody to a coreceptor (CXCR4) is both cell type and virus strain dependent. J Virol. 1997 Feb; 71(2):1692-6.
McKnight A, Wilkinson D, Simmons G, Talbot S, Picard L, Ahuja M, Marsh M, Hoxie JA, Clapham PR. PMID: 8995702; PMCID: PMC191233.
View in:
PubMed Mentions:
67 Fields:
Translation:
HumansAnimalsCells
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Primary, syncytium-inducing human immunodeficiency virus type 1 isolates are dual-tropic and most can use either Lestr or CCR5 as coreceptors for virus entry. J Virol. 1996 Dec; 70(12):8355-60.
Simmons G, Wilkinson D, Reeves JD, Dittmar MT, Beddows S, Weber J, Carnegie G, Desselberger U, Gray PW, Weiss RA, Clapham PR. PMID: 8970955; PMCID: PMC190923.
View in:
PubMed Mentions:
148 Fields:
Translation:
HumansCells
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Location, exposure, and conservation of neutralizing and nonneutralizing epitopes on human immunodeficiency virus type 2 SU glycoprotein. J Virol. 1996 Jul; 70(7):4598-606.
McKnight A, Shotton C, Cordell J, Jones I, Simmons G, Clapham PR. PMID: 8676486; PMCID: PMC190396.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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Cell-to-cell fusion, but not virus entry in macrophages by T-cell line tropic HIV-1 strains: a V3 loop-determined restriction. Virology. 1995 Jun 01; 209(2):696-700.
Simmons G, McKnight A, Takeuchi Y, Hoshino H, Clapham PR. PMID: 7778305.
View in:
PubMed Mentions:
18 Fields:
Translation:
HumansCells
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Is CD4 sufficient for HIV entry? Cell surface molecules involved in HIV infection. Philos Trans R Soc Lond B Biol Sci. 1993 Oct 29; 342(1299):67-73.
Clapham P, McKnight A, Simmons G, Weiss R. PMID: 7904349.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells