Sarah Kaufman, MD, PhD

Title(s)Assistant Professor, Neurology
SchoolSchool of Medicine
Address35 Medical Center Way, #435
San Francisco CA 94143
Phone415-353-2273
PronounsShe/Her/Hers
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    Other Positions
    Title(s)UCSF Weill Institute for Neurosciences


    Collapse Research 
    Collapse research activities and funding
    Investigating the Propagation and Pattern of Spread of Unique Tau Strains
    NIH F30AG048653Jun 1, 2014 - May 31, 2018
    Role: Principal Investigator

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. β-Amyloid Induces Microglial Expression of GPC4 and APOE Leading to Increased Neuronal Tau Pathology and Toxicity. bioRxiv. 2025 Feb 25. Holmes BB, Weigel TK, Chung JM, Kaufman SK, Apresa BI, Byrnes JR, Kumru KS, Vaquer-Alicea J, Gupta A, Rose IVL, Zhang Y, Nana AL, Alter D, Grinberg LT, Spina S, Leung KK, Condello C, Kampmann M, Seeley WW, Coutinho-Budd JC, Wells JA. PMID: 40060520; PMCID: PMC11888210.
      View in: PubMed   Mentions:
    2. Early CA2 Tau Inclusions Do Not Distinguish an Age-Related Tauopathy from Early Alzheimer's Disease. J Alzheimers Dis. 2024; 101(4):1333-1353. Del Tredici K, Schön M, Feldengut S, Ghebremedhin E, Kaufman SK, Wiesner D, Roselli F, Mayer B, Amunts K, Braak H. PMID: 39302368.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    3. Tau seeding in chronic traumatic encephalopathy parallels disease severity. Acta Neuropathol. 2021 12; 142(6):951-960. Kaufman SK, Svirsky S, Cherry JD, McKee AC, Diamond MI. PMID: 34626223; PMCID: PMC8763021.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    4. Rebuttal to Drs. Grinberg and Heinsen. Acta Neuropathol. 2018 11; 136(5):819. Kaufman SK, Del Tredici K, Braak H, Diamond MI. PMID: 30284035; PMCID: PMC6311124.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    5. Tau seeding activity begins in the transentorhinal/entorhinal regions and anticipates phospho-tau pathology in Alzheimer's disease and PART. Acta Neuropathol. 2018 07; 136(1):57-67. Kaufman SK, Del Tredici K, Thomas TL, Braak H, Diamond MI. PMID: 29752551; PMCID: PMC6015098.
      View in: PubMed   Mentions: 127     Fields:    Translation:HumansAnimalsCells
    6. Characterization of tau prion seeding activity and strains from formaldehyde-fixed tissue. Acta Neuropathol Commun. 2017 06 07; 5(1):41. Kaufman SK, Thomas TL, Del Tredici K, Braak H, Diamond MI. PMID: 28587664; PMCID: PMC5461712.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    7. Tau Prion Strains Dictate Patterns of Cell Pathology, Progression Rate, and Regional Vulnerability In Vivo. Neuron. 2016 Nov 23; 92(4):796-812. Kaufman SK, Sanders DW, Thomas TL, Ruchinskas AJ, Vaquer-Alicea J, Sharma AM, Miller TM, Diamond MI. PMID: 27974162; PMCID: PMC5392364.
      View in: PubMed   Mentions: 228     Fields:    Translation:HumansAnimalsCells
    8. Prions and Protein Assemblies that Convey Biological Information in Health and Disease. Neuron. 2016 Feb 03; 89(3):433-48. Sanders DW, Kaufman SK, Holmes BB, Diamond MI. PMID: 26844828; PMCID: PMC4748384.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimals
    9. Distinct tau prion strains propagate in cells and mice and define different tauopathies. Neuron. 2014 Jun 18; 82(6):1271-88. Sanders DW, Kaufman SK, DeVos SL, Sharma AM, Mirbaha H, Li A, Barker SJ, Foley AC, Thorpe JR, Serpell LC, Miller TM, Grinberg LT, Seeley WW, Diamond MI. PMID: 24857020; PMCID: PMC4171396.
      View in: PubMed   Mentions: 473     Fields:    
    10. Prion-like propagation of protein aggregation and related therapeutic strategies. Neurotherapeutics. 2013 Jul; 10(3):371-82. Kaufman SK, Diamond MI. PMID: 23801258; PMCID: PMC3701767.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    11. Effects of sildenafil on nigrostriatal dopamine neurons in a murine model of Parkinson's disease. J Alzheimers Dis. 2008 Sep; 15(1):97-107. Janis KL, Brennan RT, Drolet RE, Behrouz B, Kaufman SK, Lookingland KJ, Goudreau JL. PMID: 18780970.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
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