Steinunn Baekkeskov, PhD

Title(s)Professor Emeritus, Diabetes Center
SchoolSchool of Medicine
AddressLocation Required, #001
ORCID ORCID Icon0000-0003-0878-3188 Additional info
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    Collapse Research Activities and Funding
    NIH R21DK055977Sep 30, 1999 - Aug 31, 2002
    Role: Principal Investigator
    NIH R01DK047043Apr 1, 1994 - Mar 31, 2003
    Role: Principal Investigator
    NIH R55DK041567Sep 30, 1991 - Sep 29, 1993
    Role: Principal Investigator
    NIH P01DK041822Aug 1, 1989 - Jul 31, 2001
    Role: Co-Investigator
    NIH M01RR001271Dec 1, 1981 - Mar 31, 2007
    Role: Co-Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Mechanism and effects of pulsatile GABA secretion from cytosolic pools in the human beta cell. Nat Metab. 2019 11; 1(11):1110-1126. Menegaz D, Hagan DW, Almaça J, Cianciaruso C, Rodriguez-Diaz R, Molina J, Dolan RM, Becker MW, Schwalie PC, Nano R, Lebreton F, Kang C, Sah R, Gaisano HY, Berggren PO, Baekkeskov S, Caicedo A, Phelps EA. PMID: 32432213; PMCID: PMC7236889.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    2. Bioengineering strategies for inducing tolerance in autoimmune diabetes. Adv Drug Deliv Rev. 2017 05 15; 114:256-265. Baekkeskov S, Hubbell JA, Phelps EA. PMID: 28625830.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    3. Corrigendum: Advances in pancreatic islet monolayer culture on glass surfaces enable super-resolution microscopy and insights into beta cell ciliogenesis and proliferation. Sci Rep. 2017 05 09; 7:46801. Phelps EA, Cianciaruso C, Santo-Domingo J, Pasquier M, Galliverti G, Piemonti L, Berishvili E, Burri O, Wiederkehr A, Hubbell JA, Baekkeskov S. PMID: 28485397; PMCID: PMC5422918.
      View in: PubMed   Mentions:    Fields:    
    4. Advances in pancreatic islet monolayer culture on glass surfaces enable super-resolution microscopy and insights into beta cell ciliogenesis and proliferation. Sci Rep. 2017 04 12; 7:45961. Phelps EA, Cianciaruso C, Santo-Domingo J, Pasquier M, Galliverti G, Piemonti L, Berishvili E, Burri O, Wiederkehr A, Hubbell JA, Baekkeskov S. PMID: 28401888; PMCID: PMC5388888.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    5. Primary Human and Rat β-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity. Diabetes. 2017 02; 66(2):460-473. Cianciaruso C, Phelps EA, Pasquier M, Hamelin R, Demurtas D, Alibashe Ahmed M, Piemonti L, Hirosue S, Swartz MA, De Palma M, Hubbell JA, Baekkeskov S. PMID: 27872147.
      View in: PubMed   Mentions: 90     Fields:    Translation:HumansAnimalsCells
    6. Aberrant Accumulation of the Diabetes Autoantigen GAD65 in Golgi Membranes in Conditions of ER Stress and Autoimmunity. Diabetes. 2016 09; 65(9):2686-99. Phelps EA, Cianciaruso C, Michael IP, Pasquier M, Kanaani J, Nano R, Lavallard V, Billestrup N, Hubbell JA, Baekkeskov S. PMID: 27284108; PMCID: PMC5001175.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    7. Compartmentalization of GABA synthesis by GAD67 differs between pancreatic beta cells and neurons. PLoS One. 2015; 10(2):e0117130. Kanaani J, Cianciaruso C, Phelps EA, Pasquier M, Brioudes E, Billestrup N, Baekkeskov S. PMID: 25647668; PMCID: PMC4315522.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    8. Two distinct mechanisms target GAD67 to vesicular pathways and presynaptic clusters. J Cell Biol. 2010 Sep 06; 190(5):911-25. Kanaani J, Kolibachuk J, Martinez H, Baekkeskov S. PMID: 20805323; PMCID: PMC2935578.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    9. Homing of GAD65 specific autoimmunity and development of insulitis requires expression of both DQ8 and human GAD65 in transgenic mice. J Autoimmun. 2009 Aug; 33(1):50-7. Elagin RB, Balijepalli S, Diacovo MJ, Baekkeskov S, Jaume JC. PMID: 19289270; PMCID: PMC2705176.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    10. Palmitoylation cycles and regulation of protein function (Review). Mol Membr Biol. 2009 Jan; 26(1):42-54. Baekkeskov S, Kanaani J. PMID: 19169934.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansCells
    11. A palmitoylation cycle dynamically regulates partitioning of the GABA-synthesizing enzyme GAD65 between ER-Golgi and post-Golgi membranes. J Cell Sci. 2008 Feb 15; 121(Pt 4):437-49. Kanaani J, Patterson G, Schaufele F, Lippincott-Schwartz J, Baekkeskov S. PMID: 18230651.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    12. Recombinant prion protein induces rapid polarization and development of synapses in embryonic rat hippocampal neurons in vitro. J Neurochem. 2005 Dec; 95(5):1373-86. Kanaani J, Prusiner SB, Diacovo J, Baekkeskov S, Legname G. PMID: 16313516.
      View in: PubMed   Mentions: 79     Fields:    Translation:AnimalsCells
    13. Palmitoylation controls trafficking of GAD65 from Golgi membranes to axon-specific endosomes and a Rab5a-dependent pathway to presynaptic clusters. J Cell Sci. 2004 Apr 15; 117(Pt 10):2001-13. Kanaani J, Diacovo MJ, El-Husseini Ael-D, Bredt DS, Baekkeskov S. PMID: 15039456.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    14. A combination of three distinct trafficking signals mediates axonal targeting and presynaptic clustering of GAD65. J Cell Biol. 2002 Sep 30; 158(7):1229-38. Kanaani J, el-Husseini Ael-D, Aguilera-Moreno A, Diacovo JM, Bredt DS, Baekkeskov S. PMID: 12356867; PMCID: PMC2173248.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    15. Isolation and characterization of human monoclonal autoantibodies to glutamic acid decarboxylase. Autoimmunity. 2002 Aug; 35(5):343-55. Hayakawa N, Premawardhana LD, Powell M, Masuda M, Arnold C, Sanders J, Evans M, Chen S, Jaume JC, Baekkeskov S, Smith BR, Furmaniak J. PMID: 12515289.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    16. Suppressive effect of glutamic acid decarboxylase 65-specific autoimmune B lymphocytes on processing of T cell determinants located within the antibody epitope. J Immunol. 2002 Jul 15; 169(2):665-72. Jaume JC, Parry SL, Madec AM, Sønderstrup G, Baekkeskov S. PMID: 12097368.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    17. Endogenous expression levels of autoantigens influence success or failure of DNA immunizations to prevent type 1 diabetes: addition of IL-4 increases safety. Eur J Immunol. 2002 01; 32(1):113-21. Wolfe T, Bot A, Hughes A, Möhrle U, Rodrigo E, Jaume JC, Baekkeskov S, von Herrath M. PMID: 11754351.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    18. Does GAD have a unique role in triggering IDDM? J Autoimmun. 2000 Nov; 15(3):279-86. Baekkeskov S, Kanaani J, Jaume JC, Kash S. PMID: 11040068.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    19. Increased expression of GAD65 and GABA in pancreatic beta-cells impairs first-phase insulin secretion. Am J Physiol Endocrinol Metab. 2000 Sep; 279(3):E684-94. Shi Y, Kanaani J, Menard-Rose V, Ma YH, Chang PY, Hanahan D, Tobin A, Grodsky G, Baekkeskov S. PMID: 10950838.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    20. A non-cleavable mutant of Fas ligand does not prevent neutrophilic destruction of islet transplants. Transplantation. 2000 May 15; 69(9):1813-7. Kang SM, Braat D, Schneider DB, O'Rourke RW, Lin Z, Ascher NL, Dichek DA, Baekkeskov S, Stock PG. PMID: 10830216.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    21. Peptide mapping and characterisation of glycation patterns of the glima 38 antigen recognised by autoantibodies in Type I diabetic patients. Diabetologia. 2000 May; 43(5):598-608. Roll U, Turck CW, Gitelman SE, Rosenthal SM, Nolte MS, Masharani U, Ziegler AG, Baekkeskov S. PMID: 10855535.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    22. A dendritic cell line genetically modified to express CTLA4-IG as a means to prolong islet allograft survival. Transplantation. 2000 Apr 15; 69(7):1440-6. O'Rourke RW, Kang SM, Lower JA, Feng S, Ascher NL, Baekkeskov S, Stock PG. PMID: 10798768.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    23. The hydrophilic isoform of glutamate decarboxylase, GAD67, is targeted to membranes and nerve terminals independent of dimerization with the hydrophobic membrane-anchored isoform, GAD65. J Biol Chem. 1999 Dec 24; 274(52):37200-9. Kanaani J, Lissin D, Kash SF, Baekkeskov S. PMID: 10601283.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    24. The role of the synthetic enzyme GAD65 in the control of neuronal gamma-aminobutyric acid release. Proc Natl Acad Sci U S A. 1999 Oct 26; 96(22):12911-6. Tian N, Petersen C, Kash S, Baekkeskov S, Copenhagen D, Nicoll R. PMID: 10536022; PMCID: PMC23160.
      View in: PubMed   Mentions: 93     Fields:    Translation:AnimalsCells
    25. Glutamate decarboxylase and GABA in pancreatic islets: lessons from knock-out mice. Horm Metab Res. 1999 May; 31(5):340-4. Kash SF, Condie BG, Baekkeskov S. PMID: 10422732.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimals
    26. High-resolution autoreactive epitope mapping and structural modeling of the 65 kDa form of human glutamic acid decarboxylase. J Mol Biol. 1999 Apr 16; 287(5):983-99. Schwartz HL, Chandonia JM, Kash SF, Kanaani J, Tunnell E, Domingo A, Cohen FE, Banga JP, Madec AM, Richter W, Baekkeskov S. PMID: 10222205.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    27. Increased anxiety and altered responses to anxiolytics in mice deficient in the 65-kDa isoform of glutamic acid decarboxylase. Proc Natl Acad Sci U S A. 1999 Feb 16; 96(4):1698-703. Kash SF, Tecott LH, Hodge C, Baekkeskov S. PMID: 9990087; PMCID: PMC15565.
      View in: PubMed   Mentions: 70     Fields:    Translation:Animals
    28. Differential protection in two transgenic lines of NOD/Lt mice hyperexpressing the autoantigen GAD65 in pancreatic beta-cells. Diabetes. 1998 Dec; 47(12):1848-56. Bridgett M, Cetkovic-Cvrlje M, O'Rourke R, Shi Y, Narayanswami S, Lambert J, Ramiya V, Baekkeskov S, Leiter EH. PMID: 9836515.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    29. Local GABA circuit control of experience-dependent plasticity in developing visual cortex. Science. 1998 Nov 20; 282(5393):1504-8. Hensch TK, Fagiolini M, Mataga N, Stryker MP, Baekkeskov S, Kash SF. PMID: 9822384; PMCID: PMC2851625.
      View in: PubMed   Mentions: 379     Fields:    Translation:AnimalsCells
    30. Epilepsy in mice deficient in the 65-kDa isoform of glutamic acid decarboxylase. Proc Natl Acad Sci U S A. 1997 Dec 09; 94(25):14060-5. Kash SF, Johnson RS, Tecott LH, Noebels JL, Mayfield RD, Hanahan D, Baekkeskov S. PMID: 9391152; PMCID: PMC28432.
      View in: PubMed   Mentions: 115     Fields:    Translation:Animals
    31. Fas ligand expression in islets of Langerhans does not confer immune privilege and instead targets them for rapid destruction. Nat Med. 1997 Jul; 3(7):738-43. Kang SM, Schneider DB, Lin Z, Hanahan D, Dichek DA, Stock PG, Baekkeskov S. PMID: 9212099.
      View in: PubMed   Mentions: 75     Fields:    Translation:AnimalsCells
    32. Phosphorylation of serine residues 3, 6, 10, and 13 distinguishes membrane anchored from soluble glutamic acid decarboxylase 65 and is restricted to glutamic acid decarboxylase 65alpha. J Biol Chem. 1997 Jan 17; 272(3):1548-57. Namchuk M, Lindsay L, Turck CW, Kanaani J, Baekkeskov S. PMID: 8999827.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    33. Immune reactivity of diabetes-associated human monoclonal autoantibodies defines multiple epitopes and detects two domain boundaries in glutamate decarboxylase. J Immunol. 1996 Dec 01; 157(11):5208-14. Syren K, Lindsay L, Stoehrer B, Jury K, Lühder F, Baekkeskov S, Richter W. PMID: 8943434.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    34. Identification and characterization of glima 38, a glycosylated islet cell membrane antigen, which together with GAD65 and IA2 marks the early phases of autoimmune response in type 1 diabetes. J Clin Invest. 1996 Jun 15; 97(12):2772-83. Aanstoot HJ, Kang SM, Kim J, Lindsay LA, Roll U, Knip M, Atkinson M, Mose-Larsen P, Fey S, Ludvigsson J, Landin L, Bruining J, Maclaren N, Akerblom HK, Baekkeskov S. PMID: 8675688; PMCID: PMC507370.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    35. Value of antibodies to GAD65 combined with islet cell cytoplasmic antibodies for predicting IDDM in a childhood population. Diabetologia. 1994 Sep; 37(9):917-24. Aanstoot HJ, Sigurdsson E, Jaffe M, Shi Y, Christgau S, Grobbee D, Bruining GJ, Molenaar JL, Hofman A, Baekkeskov S. PMID: 7806022.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    36. Higher autoantibody levels and recognition of a linear NH2-terminal epitope in the autoantigen GAD65, distinguish stiff-man syndrome from insulin-dependent diabetes mellitus. J Exp Med. 1994 Aug 01; 180(2):595-606. Kim J, Namchuk M, Bugawan T, Fu Q, Jaffe M, Shi Y, Aanstoot HJ, Turck CW, Erlich H, Lennon V, Baekkeskov S. PMID: 7519242; PMCID: PMC2191592.
      View in: PubMed   Mentions: 46     Fields:    Translation:Humans
    37. Amino acid residues 24-31 but not palmitoylation of cysteines 30 and 45 are required for membrane anchoring of glutamic acid decarboxylase, GAD65. J Cell Biol. 1994 Mar; 124(6):927-34. Shi Y, Veit B, Baekkeskov S. PMID: 8132714; PMCID: PMC2119982.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    38. Differential expression of GAD65 and GAD67 in human, rat, and mouse pancreatic islets. Diabetes. 1993 Dec; 42(12):1799-808. Kim J, Richter W, Aanstoot HJ, Shi Y, Fu Q, Rajotte R, Warnock G, Baekkeskov S. PMID: 8243826.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansAnimalsCells
    39. Pancreatic beta cells cultured from individual preneoplastic foci in a multistage tumorigenesis pathway: a potentially general technique for isolating physiologically representative cell lines. Mol Cell Biol. 1993 Jul; 13(7):4223-32. Radvanyi F, Christgau S, Baekkeskov S, Jolicoeur C, Hanahan D. PMID: 8391634; PMCID: PMC359972.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    40. Transfer of type 1 (insulin-dependent) diabetes mellitus associated autoimmunity to mice with severe combined immunodeficiency (SCID). Diabetologia. 1993 Jun; 36(6):510-5. Petersen JS, Marshall MO, Baekkeskov S, Hejnaes KR, Høier-Madsen M, Dyrberg T. PMID: 8335172.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    41. Autoreactive epitopes defined by diabetes-associated human monoclonal antibodies are localized in the middle and C-terminal domains of the smaller form of glutamate decarboxylase. Proc Natl Acad Sci U S A. 1993 Apr 01; 90(7):2832-6. Richter W, Shi Y, Baekkeskov S. PMID: 7681990; PMCID: PMC46190.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    42. The glutamate decarboxylase and 38KD autoantigens in type 1 diabetes: aspects of structure and epitope recognition. Autoimmunity. 1993; 15 Suppl:24-6. Baekkeskov S, Aanstoot HJ, Fu Q, Jaffe M, Kim J, Quan J, Richter W, Shi Y. PMID: 7692998.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    43. Differential expression of neural cell adhesion molecule and cadherins in pancreatic islets, glucagonomas, and insulinomas. Mol Endocrinol. 1992 Aug; 6(8):1332-42. Møller CJ, Christgau S, Williamson MR, Madsen OD, Niu ZP, Bock E, Baekkeskov S. PMID: 1406710.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    44. Membrane anchoring of the autoantigen GAD65 to microvesicles in pancreatic beta-cells by palmitoylation in the NH2-terminal domain. J Cell Biol. 1992 Jul; 118(2):309-20. Christgau S, Aanstoot HJ, Schierbeck H, Begley K, Tullin S, Hejnaes K, Baekkeskov S. PMID: 1321158; PMCID: PMC2290048.
      View in: PubMed   Mentions: 61     Fields:    Translation:AnimalsCells
    45. Pancreatic beta cells express two autoantigenic forms of glutamic acid decarboxylase, a 65-kDa hydrophilic form and a 64-kDa amphiphilic form which can be both membrane-bound and soluble. J Biol Chem. 1991 Dec 05; 266(34):23516. Christgau S, Schierbeck H, Aanstoot HJ, Aagaard L, Begley K, Kofod H, Hejnaes K, Baekkeskov S. PMID: 1744145.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    46. Pancreatic beta cells express two autoantigenic forms of glutamic acid decarboxylase, a 65-kDa hydrophilic form and a 64-kDa amphiphilic form which can be both membrane-bound and soluble. J Biol Chem. 1991 Nov 05; 266(31):21257-64. Christgau S, Schierbeck H, Aanstoot HJ, Aagaard L, Begley K, Kofod H, Hejnaes K, Baekkeskov S. PMID: 1939164.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    47. Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase. Nature. 1990 Sep 13; 347(6289):151-6. Baekkeskov S, Aanstoot HJ, Christgau S, Reetz A, Solimena M, Cascalho M, Folli F, Richter-Olesen H, De Camilli P, Camilli PD. PMID: 1697648.
      View in: PubMed   Mentions: 412     Fields:    Translation:Animals
    48. Cellular and subcellular localization of an Mr 64,000 protein autoantigen in insulin-dependent diabetes. J Biol Chem. 1990 Jan 05; 265(1):376-81. Christie MR, Pipeleers DG, Lernmark A, Baekkeskov S. PMID: 2403561.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    49. The 64-kDa beta cell membrane autoantigen and other target molecules of humoral autoimmunity in insulin-dependent diabetes mellitus. Curr Top Microbiol Immunol. 1990; 164:143-68. Sigurdsson E, Baekkeskov S. PMID: 2073783.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    50. Revelation of specificity of 64K autoantibodies in IDDM serums by high-resolution 2-D gel electrophoresis. Unambiguous identification of 64K target antigen. Diabetes. 1989 Sep; 38(9):1133-41. Baekkeskov S, Warnock G, Christie M, Rajotte RV, Larsen PM, Fey S. PMID: 2670643.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimals
    51. Preclinical and manifest diabetes mellitus in young patients with Friedreich's ataxia: no evidence of immune process behind the islet cell destruction. Diabetologia. 1989 Jun; 32(6):378-81. Schoenle EJ, Boltshauser EJ, Baekkeskov S, Landin Olsson M, Torresani T, von Felten A. PMID: 2668085.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    52. Supravital dithizone staining in the isolation of human and rat pancreatic islets. Diabetes Res. 1989 Feb; 10(2):53-7. Hansen WA, Christie MR, Kahn R, Norgaard A, Abel I, Petersen AM, Jorgensen DW, Baekkeskov S, Nielsen JH, Lernmark A, et al. PMID: 2545405.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    53. Beta-cell lines derived from transgenic mice expressing a hybrid insulin gene-oncogene. Proc Natl Acad Sci U S A. 1988 Dec; 85(23):9037-41. Efrat S, Linde S, Kofod H, Spector D, Delannoy M, Grant S, Hanahan D, Baekkeskov S. PMID: 2848253; PMCID: PMC282658.
      View in: PubMed   Mentions: 162     Fields:    Translation:AnimalsCells
    54. Antibodies to a Mr-64,000 islet cell protein in Swedish children with newly diagnosed type 1 (insulin-dependent) diabetes. Diabetologia. 1988 Aug; 31(8):597-602. Christie M, Landin-Olsson M, Sundkvist G, Dahlquist G, Lernmark A, Baekkeskov S. PMID: 3065114.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimals
    55. Studies of the isolation and viability of human islets of Langerhans. Transplantation. 1988 May; 45(5):957-63. Warnock GL, Ellis D, Rajotte RV, Dawidson I, Baekkeskov S, Egebjerg J. PMID: 2835843.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    56. [Spontaneous diabetes and diabetes induced by streptozotocin in the rat and mouse]. Journ Annu Diabetol Hotel Dieu. 1988; 15-31. Lernmark A, Markholst H, Laursen H, Contreas G, Altieri M, Baekkeskov S, Herold R, Kastern W, Madsen OD. PMID: 2971832.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    57. Islet-specific immune mechanisms. Diabetes Metab Rev. 1987 Oct; 3(4):959-80. Lernmark A, Li S, Baekkeskov S, Christie M, Michelsen B, Ursing J, Olsson ML, Sundkvist G. PMID: 3315527.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    58. Coordinate expression of the endogenous p53 gene in beta cells of transgenic mice expressing hybrid insulin-SV40 T antigen genes. EMBO J. 1987 Sep; 6(9):2699-704. Efrat S, Baekkeskov S, Lane D, Hanahan D. PMID: 2824189; PMCID: PMC553692.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    59. Antibodies to a 64,000 Mr human islet cell antigen precede the clinical onset of insulin-dependent diabetes. J Clin Invest. 1987 Mar; 79(3):926-34. Baekkeskov S, Landin M, Kristensen JK, Srikanta S, Bruining GJ, Mandrup-Poulsen T, de Beaufort C, Soeldner JS, Eisenbarth G, Lindgren F, et al. PMID: 3546382; PMCID: PMC424239.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansCells
    60. Islet cell and 64K autoantibodies are associated with plasma IgG in newly diagnosed insulin-dependent diabetic children. J Immunol. 1986 Dec 15; 137(12):3782-5. Gerling I, Baekkeskov S, Lernmark A. PMID: 3537124.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    61. Immunoreactivity to a 64,000 Mr human islet cell antigen in sera from insulin-dependent diabetes mellitus patients and individuals with abnormal glucose tolerance. Mol Biol Med. 1986 Apr; 3(2):137-42. Baekkeskov S. PMID: 3526081.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    62. Immunological aspects of type 1 and 2 diabetes mellitus. Adv Exp Med Biol. 1985; 189:107-27. Lernmark A, Baekkeskov S, Gerling I, Kastern W, Knutson C, Michelsen B. PMID: 4036712.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    63. [Mechanism and genetic control of the autoimmune response directed against beta-pancreatic cells in insulin-dependent diabetes]. Journ Annu Diabetol Hotel Dieu. 1985; 171-82. Michelsen B, Baekkeskov S, Deufel T, Kastern W, Kofod H, Lernmark A, Vissing H. PMID: 2577960.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    64. A beta-cell glycoprotein of Mr 40 000 is the major rat islet cell immunogen following xenogenic immunisation. Diabetologia. 1984 Jul; 27 Suppl:70-3. Baekkeskov S, Lernmark A. PMID: 6383923.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsPHPublic Health
    65. Autoantibodies to a 64-kilodalton islet cell protein precede the onset of spontaneous diabetes in the BB rat. Science. 1984 Jun 22; 224(4655):1348-50. Baekkeskov S, Dyrberg T, Lernmark A. PMID: 6374896.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimals
    66. Glucose stimulates the biosynthesis of a human pancreatic islet cell protein detected by an antiserum against the human erythrocyte glucose transporter. FEBS Lett. 1983 Jul 04; 157(2):331-5. Baekkeskov S, Lernmark A. PMID: 6190679.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    67. Immunoglobulin from insulin-dependent diabetic children inhibits glucose-induced insulin release. Diabetes. 1983 Jun; 32(6):520-4. Kanatsuna T, Baekkeskov S, Lernmark A, Ludvigsson J. PMID: 6354781.
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    68. Role of islet cell antibodies in the pathogenesis of type I diabetes. Curr Probl Clin Biochem. 1983; 12:65-85. Brogren CH, Baekkeskov S, Dyrberg T, Lernmark A, Marner B, Nerup J, Papadopoulos GK. PMID: 6360543.
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    69. Specific pancreatic beta-cell surface antigens recognized by a xenogenic antiserum. J Cell Biol. 1982 Aug; 94(2):472-7. Dyrberg T, Baekkeskov S, Lernmark A. PMID: 7050130; PMCID: PMC2112876.
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    70. Autoantibodies in newly diagnosed diabetic children immunoprecipitate human pancreatic islet cell proteins. Nature. 1982 Jul 08; 298(5870):167-9. Baekkeskov S, Nielsen JH, Marner B, Bilde T, Ludvigsson J, Lernmark A. PMID: 7045690.
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    71. Islet cell surface antibodies and lymphocyte antibodies in the spontaneously diabetic BB Wistar rat. Diabetes. 1982 Mar; 31(3):278-81. Dyrberg T, Nakhooda AF, Baekkeskov S, Lernmark A, Poussier P, Marliss EB. PMID: 6759244.
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    72. Rodent islet cell antigens recognized by antibodies in sera from diabetic patients. Acta Biol Med Ger. 1982; 41(12):1111-5. Baekkeskov S, Lernmark A. PMID: 6765152.
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    73. Islet cell antibodies-theoretical and practical implications. Diabetologia. 1981 Nov; 21(5):431-5. Lernmark A, Baekkeskov S. PMID: 7028555.
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    74. Expression of major histocompatibility antigens on pancreatic islet cells. Proc Natl Acad Sci U S A. 1981 Oct; 78(10):6456-60. Baekkeskov S, Kanatsuna T, Klareskog L, Nielsen DA, Peterson PA, Rubenstein AH, Steiner DF, Lernmark A. PMID: 7031653; PMCID: PMC349058.
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    75. Islet transplantation in mice differing in the I and S subregions of the H-2 complex. Transplantation. 1981 Jun; 31(6):476-9. Steffes MW, Nielsen O, Dyrberg T, Baekkeskov S, Scott J, Lernmark A. PMID: 6789509.
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    76. Sub-cellular fractionation of Trypanosoma brucei. Isolation and characterization of plasma membranes. Parasitology. 1980 Jun; 80(3):507-24. Rovis L, Baekkeskov S. PMID: 6248830.
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