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Yiwey Shieh, MD

Photo of Yiwey Shieh, MD
Title(s)Affiliate, Surgery
SchoolSchool of Medicine
AddressLocation Required, #001
ORCID ORCID Icon0000-0002-0159-7748 Additional info
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    Collapse Biography 
    Collapse education and training
    Harvard UniversityAB2006Biology
    University of California, San FranciscoMD2012School of Medicine
    Hospital of the University of PennsylvaniaResidency2015Internal Medicine - Primary Care
    University of California, San FranciscoMAS2017Clinical Research
    Collapse awards and honors
    UCSF Breast Oncology Program2017Best Poster, Epidemiology and Population Science
    Society of General Internal Medicine2017Finalist, Mack Lipkin Sr. Associate Member Scientific Presentation Award
    Society of General Internal Medicine2018Winner, Milton W. Hamolsky Junior Faculty Scientific Presentation Award

    Collapse Overview 
    Collapse overview
    Yiwey Shieh, MD is an Assistant Professor in the Department of Medicine at the University of California, San Francisco (UCSF). Dr. Shieh is a general internist and clinical epidemiologist interested in improving the delivery of breast cancer screening and prevention through the use of risk stratification tools. His current work uses clinical risk factors, breast density, and genetic variants to refine individualized risk assessment, especially as it pertains to disease biology. As a clinician-investigator, he is particularly interested in how such tools can be used to improve clinical decision-making.

    Collapse Research 
    Collapse research activities and funding
    Prediction of interval breast cancer risk using genetic variants
    NIH K08CA237829Jul 1, 2019 - Jun 30, 2024
    Role: Principal Investigator
    UCSF CTSI KL2 Career Development Award
    NIH/NCATS 1KL2TR001870Jun 1, 2018 - Jun 30, 2019
    Role: KL2 Scholar

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Integrating breast cancer polygenic risk scores at scale in the WISDOM Study: a national randomized personalized screening trial. Genome Med. 2025 Aug 28; 17(1):97. Fergus KB, Heise RS, Madlensky L, Fiscalini A, Sabacan L, Theiner S, Kapoor S, Soto IA, Blanco A, Ross K, Goodman-Gruen D, Scheuner M, Hu D, Heditsian D, Brain S, Arasu VA, Kaster A, Chapa L, Olopade OI, Eklund M, Tice JA, Ziv E, van 't Veer L, Esserman LJ, Shieh Y, Athena/WISDOM Network Collaborators and Advocate Partners. PMID: 40877879; PMCID: PMC12395744.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Whole exome sequencing identifies FANCM as a susceptibility gene for estrogen-receptor-negative breast cancer in Hispanic/Latina women. Nat Commun. 2025 Aug 21; 16(1):7816. Nierenberg JL, Adamson AW, Hu D, Huntsman S, Patrick C, Li M, Steele L, Tao S, Ding YC, Tong B, Shieh Y, Fejerman L, Gruber SB, Haiman CA, John EM, Kushi LH, Torres-Mejía G, Ricker C, Weitzel JN, Ziv E, Neuhausen SL. PMID: 40841357; PMCID: PMC12370925.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Ubiquitin-like with phd and ring finger domains 1 as a potential therapeutic target in smoking-associated oral squamous cell carcinoma. J Dent Sci. 2025 Jul; 20(3):1772-1781. Wu JR, Yeh CT, Chien CY, Chen YC, Huang TW, Lin CY, Cheng-Ting Hsieh A, Hung YJ, Shieh YS. PMID: 40654427; PMCID: PMC12254763.
      View in: PubMed   Mentions:
    4. Cytokine and epigenetic regulation of CEACAM6 mediates EGFR-driven signaling and drug response in lung adenocarcinoma. NPJ Precis Oncol. 2025 Apr 22; 9(1):115. Zheng MY, Lin YT, Kuo YS, Lin YJ, Kuo MH, Huang TW, Shieh YS, Huang Y, Chou YT. PMID: 40263546; PMCID: PMC12015248.
      View in: PubMed   Mentions: 1  
    5. Abstract 3582: Lung cancer screening in breast cancer survivors: a comparison of the USPSTF guidelines and risk-based criteria. Cancer Research. 2025 Apr 21; 85(8_Supplement_1):3582-3582. Wang WB, Michael MM, Lee LJ, Shieh SY, Groner GL, Backus BL, Kurian KA, Tamimi TR, Han HS, Choi CE. .
      View in: Publisher Site   Mentions:
    6. Abstract 3376: Real-world cancer treatment patterns and their effects in older adults with lung cancer: a SEER-MHOS analysis. Cancer Research. 2025 Apr 21; 85(8_Supplement_1):3376-3376. Qiu QS, Xu XY, Pinheiro PL, Mao MJ, Shi SY, Shieh SY, Garcia GC, Choi CE. .
      View in: Publisher Site   Mentions:
    7. Abstract 3370: MCC-MELD: A diverse lung cancer registry with detailed molecular and environmental annotation. Cancer Research. 2025 Apr 21; 85(8_Supplement_1):3370-3370. Cui CL, Lee LJ, Abedian AS, Tang TM, Solomon SJ, Crupi CR, Miller MJ, Gao GH, Sholle SE, Garcia GC, Choi CE, Shieh SY. .
      View in: Publisher Site   Mentions:
    8. Abstract 3582: Lung cancer screening in breast cancer survivors: a comparison of the USPSTF guidelines and risk-based criteria. Cancer Research. 2025 Apr 21; 85(8_Supplement_1):3582-3582. Wang WB, Michael MM, Lee LJ, Shieh SY, Groner GL, Backus BL, Kurian KA, Tamimi TR, Han HS, Choi CE. .
      View in: Publisher Site   Mentions:
    9. Abstract 3370: MCC-MELD: A diverse lung cancer registry with detailed molecular and environmental annotation. Cancer Research. 2025 Apr 21; 85(8_Supplement_1):3370-3370. Cui CL, Lee LJ, Abedian AS, Tang TM, Solomon SJ, Crupi CR, Miller MJ, Gao GH, Sholle SE, Garcia GC, Choi CE, Shieh SY. .
      View in: Publisher Site   Mentions:
    10. National yearly cost of breast cancer screening in the USA and projected cost of advocated guidelines: a simulation study with life table modelling. BMJ Open. 2025 Feb 17; 15(2):e089428. Badal K, Staib J, Tice JA, Kim MO, Eklund M, Wilson L, Dacosta Byfield S, Catlett K, Maffey L, Soonavala R, Shieh Y, Esserman LJ. PMID: 39961709; PMCID: PMC11836805.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    11. Validation study of risk-reduction activities after personalized breast cancer education tool in the WISDOM study. NPJ Breast Cancer. 2024 Oct 14; 10(1):90. Wang T, Che M, Huilgol YS, Keane H, Goodman D, Soonavala R, Ozanne E, Shieh Y, Belkora JK, Fiscalini AS, Athena Breast Health Network Investigators and Advocate Partners, Esserman LJ. PMID: 39397069; PMCID: PMC11471852.
      View in: PubMed   Mentions: 1  
    12. P2.07B.09 Real-World Validation for Impact of Sublobar Resection Over Lobectomy on Lung Cancer Survival and Frailty Using SEER-Medicare. Journal of Thoracic Oncology. 2024 Oct 1; 19(10):s238-s239. Choi CE, Su SC, Shi SY, Groner GL, Pua PB, Crupi CR, Mao MJ, Jung JH, Garcia GC, Pinheiro PL, Sholle SE, Shieh SY, Tamimi TR, Sedrakyan SA, Han HS, Altorki AN, Mandelblatt MJ. .
      View in: Publisher Site   Mentions:
    13. P2.07B.09 Real-World Validation for Impact of Sublobar Resection Over Lobectomy on Lung Cancer Survival and Frailty Using SEER-Medicare. Journal of Thoracic Oncology. 2024 Oct 1; 19(10):s238-s239. Choi CE, Su SC, Shi SY, Groner GL, Pua PB, Crupi CR, Mao MJ, Jung JH, Garcia GC, Pinheiro PL, Sholle SE, Shieh SY, Tamimi TR, Sedrakyan SA, Han HS, Altorki AN, Mandelblatt MJ. .
      View in: Publisher Site   Mentions:
    14. Protein inhibitor of activated signal transducer and activator of transcription 2 is an oncoprotein in oral squamous cell carcinoma and related to cigarette smoking - An in vitro study. J Dent Sci. 2024 Oct; 19(4):1983-1990. Chen SY, Chiang CF, Su YF, Lin CY, Hung YJ, Huang TW, Shieh YS. PMID: 39347031; PMCID: PMC11437306.
      View in: PubMed   Mentions:
    15. Association of germline polygenic risk for thyroid autoimmunity with overall survival in the I-SPY2 Trial. Journal of Clinical Oncology. 2024 Jun 1; 42(16_suppl):10600-10600. Fergus FK, Middha MP, Quandt QZ, Shieh SY, Basu BA, Sayaman SR, Pohlmann PP, Yee YD, Shatsky SR, Isaacs IC, Campbell CM, Hirst HG, Brown Swigart BL, van 't Veer vL, Ziv ZE, Esserman EL. .
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    16. MyD88 exacerbates inflammation-induced bone loss by modulating dynamic equilibrium between Th17/Treg cells and subgingival microbiota dysbiosis. J Periodontol. 2024 Aug; 95(8):764-777. Hsiao PY, Huang RY, Huang LW, Chu CL, Dyke TV, Mau LP, Cheng CD, Sung CE, Weng PW, Wu YC, Shieh YS, Cheng WC. PMID: 38523602.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    17. Public cervical cancer screening recommendations from US cancer centers: Assessing adherence to national guidelines. J Med Screen. 2024 Sep; 31(3):201-204. Salingaros S, Shieh Y, Finkel ML, Polaneczky M, Korenstein D, Marti JL. PMID: 38504656.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansPHPublic Health
    18. Nuclear translocation of Axl contributes to the malignancy of oral cancer cells. J Dent Sci. 2024 Jan; 19(1):438-447. Su YF, Shen PC, Huang WY, Hung YJ, Huang TW, Lin CY, Shieh YS. PMID: 38303797; PMCID: PMC10829653.
      View in: PubMed   Mentions:
    19. MiR-34a functions as a tumor suppressor in oral cancer through the inhibition of the Axl/Akt/GSK-3β pathway. J Dent Sci. 2024 Jan; 19(1):428-437. Su YF, Lin CS, Shen PC, Chuang SE, Dai YH, Huang TW, Lin CY, Hung YJ, Shieh YS. PMID: 38303867; PMCID: PMC10829669.
      View in: PubMed   Mentions: 3  
    20. Complement components C3b and C4b as potential reliable site-specific diagnostic biomarkers for periodontitis. J Periodontal Res. 2023 Oct; 58(5):1020-1030. Huang RY, Tseng FY, Cheng CD, Van Dyke TE, Sung CE, You JJ, Weng PW, Shieh YS, Cheng WC. PMID: 37462259.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    21. The referral pattern and treatment modality for peri-implant disease between periodontists and non-periodontist dentists. BMC Oral Health. 2023 06 27; 23(1):427. Cheng CD, Tsai YC, Cheng WC, Lin FG, Weng PW, Chen YW, Huang RY, Chen WL, Shieh YS, Sung CE. PMID: 37370067; PMCID: PMC10303747.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    22. Development and testing of a polygenic risk score for breast cancer aggressiveness. NPJ Precis Oncol. 2023 May 15; 7(1):42. Shieh Y, Roger J, Yau C, Wolf DM, Hirst GL, Swigart LB, Huntsman S, Hu D, Nierenberg JL, Middha P, Heise RS, Shi Y, Kachuri L, Zhu Q, Yao S, Ambrosone CB, Kwan ML, Caan BJ, Witte JS, Kushi LH, 't Veer LV, Esserman LJ, Ziv E. PMID: 37188791; PMCID: PMC10185660.
      View in: PubMed   Mentions: 8  
    23. Validation Study on Risk-Reduction Activities after Exposure to a Personalized Breast Cancer Risk-Assessment Education Tool in High-Risk Women in the WISDOM Study. Res Sq. 2023 May 10. Wang T, Che M, Huilgol YS, Keane H, Goodman D, Soonavala R, Ozanne E, Shieh Y, Belkora JK, Fiscalini AS, Athena Breast Health Network Investigators and Advocate Partners, Esserman LJ. PMID: 37214889; PMCID: PMC10197747.
      View in: PubMed   Mentions:
    24. Mapping out the bibliometric characteristics of classic articles published in a Taiwanese academic journal in dentistry: A scopus-based analysis. J Dent Sci. 2023 Oct; 18(4):1493-1509. Chen MC, Chen SH, Cheng CD, Chung CH, Mau LP, Sung CE, Weng PW, Cathy Tsai YW, Shieh YS, Huang RY, Cheng WC. PMID: 37799889; PMCID: PMC10547996.
      View in: PubMed   Mentions: 5  
    25. Silibinin alleviates inflammation-induced bone loss by modulating biological interaction between human gingival fibroblasts and monocytes. J Periodontol. 2023 07; 94(7):905-918. Huang RY, Chang HY, Chih SM, Dyke TV, Cheng CD, Sung CE, Weng PW, Shieh YS, Cheng WC. PMID: 36716169.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    26. Abstract PD14-07: PD14-07 Associations of Breast Cancer Risk Level and Prediction of Tumor Aggressiveness in the Athena Breast Health Network. Cancer Research. 2023 Mar 1; 83(5_Supplement):pd14-07-pd14-07. Leggat-Barr LK, Lewis LT, Sayaman SR, Warner WP, Malvin MK, Sabacan SL, Tsopurashvili TE, Fiscalini FA, Tice TJ, Kerlikowske KK, Shieh SY, Esserman EL, Van ’t Veer VL. .
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    27. Abstract P5-04-08: Breast cancer screening using ultrasound increases recall, biopsy, and cancer detection rates. Cancer Research. 2023 Mar 1; 83(5_Supplement):p5-04-08-p5-04-08. Staib SJ, Soonavala SR, Byfield BS, Badal BK, Catlett CK, Maffey ML, Kim KM, Wimmer WK, Shieh SY, Esserman EL. .
      View in: Publisher Site   Mentions:
    28. Targeting therapeutic agent against C3b/C4b, SB002, on the inflammation-induced bone loss in experimental periodontitis. J Clin Periodontol. 2023 05; 50(5):657-670. Huang RY, Tseng FY, You JJ, Van Dyke TE, Cheng CD, Sung CE, Weng PW, Shieh YS, Cheng WC. PMID: 36632003.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    29. Whole exome sequencing and replication for breast cancer among Hispanic/Latino women identifies FANCM as a susceptibility gene for estrogen-receptor-negative breast cancer. medRxiv. 2023 Jan 28. Nierenberg JL, Adamson AW, Hu D, Huntsman S, Patrick C, Li M, Steele L, Tong B, Shieh Y, Fejerman L, Gruber SB, Haiman CA, John EM, Kushi LH, Torres-Mejía G, Ricker C, Weitzel JN, Ziv E, Neuhausen SL. PMID: 36747679; PMCID: PMC9901069.
      View in: PubMed   Mentions:
    30. Abstract PR008: Development and testing of a polygenic risk score for breast cancer. Aggressiveness. Cancer Prevention Research. 2023 Jan 1; 16(1_Supplement):pr008-pr008. Shieh SY, Roger RJ, Yau YC, Wolf WD, Hirst HG, Swigart SL, Huntsman HS, Hu HD, Nierenberg NJ, Middha MP, Heise HR, Kachuri KL, Zhu ZQ, Yao YS, Ambrosone AC, Kwan KM, Caan CB, Witte WJ, Kushi KL, Veer VL, Esserman EL, Ziv ZE. .
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    31. PDIA4, a new endoplasmic reticulum stress protein, modulates insulin resistance and inflammation in skeletal muscle. Front Endocrinol (Lausanne). 2022; 13:1053882. Lee CH, Chiang CF, Lin FH, Kuo FC, Su SC, Huang CL, Li PF, Liu JS, Lu CH, Hsieh CH, Hung YJ, Shieh YS. PMID: 36619574; PMCID: PMC9816868.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
    32. Abstract 5883: Development and testing of a polygenic risk score for proliferative breast cancers. Cancer Research. 2022 Jun 15; 82(12_Supplement):5883-5883. Shieh SY, Roger RJ, Huntsman HS, Hu HD, Nierenberg NJ, Kapoor KP, Yau YC, Hirst HG, van 't Veer vL, Esserman EL. .
      View in: Publisher Site   Mentions:
    33. PDIA4, a novel ER stress chaperone, modulates adiponectin expression and inflammation in adipose tissue. Biofactors. 2022 Sep; 48(5):1060-1075. Su SC, Chien CY, Chen YC, Chiang CF, Lin FH, Kuo FC, Huang CL, Li PF, Liu JS, Lu CH, Ho LJ, Hsieh CH, Hung YJ, Shieh YS, Lee CH. PMID: 35674710.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    34. Effectiveness of different root-end filling materials in modern surgical endodontic treatment: A systematic review and network meta-analysis. J Dent Sci. 2022 Oct; 17(4):1731-1743. Chao YC, Chen PH, Su WS, Yeh HW, Su CC, Wu YC, Chiang HS, Jhou HJ, Shieh YS. PMID: 36299320; PMCID: PMC9588816.
      View in: PubMed   Mentions: 6  
    35. Air quality in a hospital dental department. J Dent Sci. 2022 Jul; 17(3):1350-1355. Hsu CT, Hsu SC, Huang SK, Lee CL, Shieh YS. PMID: 35784142; PMCID: PMC9236934.
      View in: PubMed   Mentions: 4  
    36. Abstract P5-19-01: The impact of streamlined processes and patient-directed messaging to improve enrollment in a remote, pragmatic clinical trial. Cancer Research. 2022 Feb 15; 82(4_Supplement):p5-19-01-p5-19-01. Choy CP, Lewis LT, Flores FS, Sabacan SL, Thannickal TH, Goodman GS, Shieh SY, Madlensky ML, Tice TJ, Ziv ZE, Eklund EM, Blanco BA, Tong TB, Goodman GD, Anderson AN, Harvey HH, Fors FS, Park PH, Petruse PA, Stewart SS, Raouf RS, Wernisch WJ, Koenig KB, Kaplan KC, Hiatt HR, Wenger WN, Lee LV, Heditsian HD, Brain BS, Moorehead MD, Parker PB, Borowsky BA, Anton-Culver AH, Naeim NA, Kaster KA, van 't Veer vL, LaCroix LA, Olopade OO, Sheth SD, Garcia GA, Lancaster LR, James JJ, Joseph JG, Study SW, Fiscallini FA, Esserman EL. .
      View in: Publisher Site   Mentions:
    37. Abstract P5-19-04: The WISDOM study: Reducing sequential steps and implementing parallel workflows in pragmatic trials. Cancer Research. 2022 Feb 15; 82(4_Supplement):p5-19-04-p5-19-04. Lewis LT, Flores FS, Sabacan SL, Choy CP, Thannickal TH, Shieh SY, Tice TJ, Ziv ZE, Madlensky ML, Eklund EM, Yau YC, Blanco BA, Tong TB, Goodman GD, Anderson AN, Harvey HH, Fors FS, Park PH, Raouf RS, Stewart SS, Wernisch WJ, Koenig KB, Kaplan KC, Hiatt HR, Wenger WN, Lee LV, Heditsian HD, Brain BS, Moorehead MD, Parker PB, Borowsky BA, Anton-Culver AH, Naeim NA, Kaster KA, van ‘t Veer vL, LaCroix LA, Olopade OO, Sheth SD, Garcia GA, Lancaster LR, Plaza PM, Fiscalini FA, Esserman EL. .
      View in: Publisher Site   Mentions:
    38. Abstract PO-164: Pathogenic variants in breast cancer risk genes in Latinas. Cancer Epidemiology Biomarkers & Prevention. 2022 Jan 1; 31(1_Supplement):po-164-po-164. Nierenberg NJ, Adamson AA, Ding DY, Shieh SY, Hu HD, Huntsman HS, John JE, Torres-Mejia TG, Haiman HC, Kushi KL, Ricker RC, Steele SL, Lee LR, Weitzel WJ, Fejerman FL, Ziv ZE, Neuhausen NS. .
      View in: Publisher Site   Mentions:
    39. A case-case analysis of women with breast cancer: predictors of interval vs screen-detected cancer. Breast Cancer Res Treat. 2022 Feb; 191(3):623-629. Dreher N, Matthys M, Hadeler E, Shieh Y, Acerbi I, McAuley FM, Melisko M, Eklund M, Tice JA, Esserman LJ, Veer LJV. PMID: 34843026; PMCID: PMC9189918.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    40. Dysregulation of the miR-30a/BiP axis by cigarette smoking accelerates oral cancer progression. Cancer Cell Int. 2021 Oct 30; 21(1):578. Chien CY, Chen YC, Lee CH, Wu JR, Huang TW, Huang RY, Cheng WC, Hsieh AC, Shieh YS. PMID: 34717640; PMCID: PMC8557586.
      View in: PubMed   Mentions: 7  
    41. The WISDOM study: a new approach to screening can and should be tested. Breast Cancer Res Treat. 2021 Oct; 189(3):593-598. Esserman L, Eklund M, Veer LV, Shieh Y, Tice J, Ziv E, Blanco A, Kaplan C, Hiatt R, Fiscalini AS, Yau C, Scheuner M, Naeim A, Wenger N, Lee V, Heditsian D, Brain S, Parker BA, LaCroix AZ, Madlensky L, Hogarth M, Borowsky A, Anton-Culver H, Kaster A, Olopade OI, Sheth D, Garcia A, Lancaster R, Plaza M. PMID: 34529196.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansPHPublic Health
    42. Obesity-associated leptin promotes chemoresistance in colorectal cancer through YAP-dependent AXL upregulation. Am J Cancer Res. 2021; 11(9):4220-4240. Chen YC, Chien CY, Hsu CC, Lee CH, Chou YT, Shiah SG, Liu SY, Yen CY, Hsieh AC, Wabitsch M, Shieh YS. PMID: 34659884; PMCID: PMC8493400.
      View in: PubMed   Mentions: 11  
    43. YAP-Dependent BiP Induction Is Involved in Nicotine-Mediated Oral Cancer Malignancy. Cells. 2021 08 13; 10(8). Chien CY, Chen YC, Hsu CC, Chou YT, Shiah SG, Liu SY, Hsieh AC, Yen CY, Lee CH, Shieh YS. PMID: 34440849; PMCID: PMC8392082.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    44. Elevated risk thresholds predict endocrine risk-reducing medication use in the Athena screening registry. NPJ Breast Cancer. 2021 Aug 03; 7(1):102. Huilgol YS, Keane H, Shieh Y, Hiatt RA, Tice JA, Madlensky L, Sabacan L, Fiscalini AS, Ziv E, Acerbi I, Che M, Anton-Culver H, Borowsky AD, Hunt S, Naeim A, Parker BA, van 't Veer LJ, Athena Breast Health Network Investigators and Advocate Partners, Esserman LJ. PMID: 34344894; PMCID: PMC8333106.
      View in: PubMed   Mentions: 3  
    45. Risk assessment of labial bone perforation in the anterior mandibular region: a virtual immediate implant placement study. Int J Implant Dent. 2021 07 26; 7(1):68. Tsai YC, Huang RY, Cheng CD, Cheng WC, Cochran DL, Nguyen TT, Shieh YS, Lin FG, Sung CE. PMID: 34308500; PMCID: PMC8310813.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    46. Development and pilot of an online, personalized risk assessment tool for a breast cancer precision medicine trial. NPJ Breast Cancer. 2021 Jun 17; 7(1):78. Keane H, Huilgol YS, Shieh Y, Tice JA, Belkora J, Sepucha K, Shibley WP, Wang T, Che M, Goodman D, Ozanne E, Fiscalini AS, Esserman LJ. PMID: 34140528; PMCID: PMC8211836.
      View in: PubMed   Mentions: 13  
    47. Long-term maxillary anteroposterior changes following maxillary protraction with or without expansion: A meta-analysis and meta-regression. PLoS One. 2021; 16(2):e0247027. Lee WC, Shieh YS, Liao YF, Lee CH, Huang CS. PMID: 33617540; PMCID: PMC7899359.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    48. Abstract OT-21-01: Personalized breast cancer screening in a population-based study: Women informed to screen depending on measures of risk (WISDOM). Cancer Research. 2021 Feb 15; 81(4_Supplement):ot-21-01-ot-21-01. Acerbi AI, Fiscalini FA, Che CM, Shieh SY, Madlensky ML, Tice TJ, Ziv ZE, Eklund EM, Blanco BA, Tong TB, Goodman GD, Nassereddine NL, Anderson AN, Harvey HH, Fors FS, Park PH, Petruse PA, Stewart SS, Wernisch WJ, Risty RL, Hurley HI, Koenig KB, Kaplan KC, Hiatt HR, Wenger WN, Lee LV, Heditsian HD, Brain BS, Sabacan SL, Wang WT, Parker PB, Borowsky BA, Anton-Culver AH, Naeim NA, Kaster KA, Talley TM, van 't Veer vL, LaCroix LA, Olopade OO, Sheth SD, Garcia GA, Lancaster LR, Esserman EL. .
      View in: Publisher Site   Mentions:
    49. MiR-944/CISH mediated inflammation via STAT3 is involved in oral cancer malignance by cigarette smoking. Neoplasia. 2020 11; 22(11):554-565. Peng HY, Hsiao JR, Chou ST, Hsu YM, Wu GH, Shieh YS, Shiah SG. PMID: 32961483; PMCID: PMC7505767.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    50. Correction to: Gamma synuclein is a novel nicotine responsive protein in oral cancer malignancy. Cancer Cell Int. 2020; 20:410. Hsu CC, Su YF, Tsai KY, Kuo FC, Chiang CF, Chien CY, Chen YC, Lee CH, Wu YC, Wang K, Liu SY, Shieh YS. PMID: 32863769; PMCID: PMC7448332.
      View in: PubMed   Mentions:
    51. Medications for Primary Prevention of Breast Cancer. JAMA. 2020 07 21; 324(3):291-292. Shieh Y, Tice JA. PMID: 32692377; PMCID: PMC8216042.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansPHPublic Health
    52. Gamma synuclein is a novel nicotine responsive protein in oral cancer malignancy. Cancer Cell Int. 2020; 20:300. Hsu CC, Su YF, Tsai KY, Kuo FC, Chiang CF, Chien CY, Chen YC, Lee CH, Wu YC, Wang K, Liu SY, Shieh YS. PMID: 32669976; PMCID: PMC7350738.
      View in: PubMed   Mentions: 7  
    53. Long-term maxillary three dimensional changes following maxillary protraction with or without expansion: A systematic review and meta-analysis. J Dent Sci. 2021 Jan; 16(1):168-177. Lee WC, Shieh YS, Liao YF, Lee CH, Huang CS. PMID: 33384794; PMCID: PMC7770293.
      View in: PubMed   Mentions: 5  
    54. A Polygenic Risk Score for Breast Cancer in US Latinas and Latin American Women. J Natl Cancer Inst. 2020 06 01; 112(6):590-598. Shieh Y, Fejerman L, Lott PC, Marker K, Sawyer SD, Hu D, Huntsman S, Torres J, Echeverry M, Bohórquez ME, Martínez-Chéquer JC, Polanco-Echeverry G, Estrada-Flórez AP, COLUMBUS Consortium, Haiman CA, John EM, Kushi LH, Torres-Mejía G, Vidaurre T, Weitzel JN, Zambrano SC, Carvajal-Carmona LG, Ziv E, Neuhausen SL. PMID: 31553449; PMCID: PMC7301155.
      View in: PubMed   Mentions: 48     Fields:    Translation:Humans
    55. Interval breast cancers - insights into a complex phenotype. Nat Rev Clin Oncol. 2020 03; 17(3):138-139. Shieh Y, Ziv E, Kerlikowske K. PMID: 31965086; PMCID: PMC10365927.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    56. Abstract P5-08-23: Personalized, prevention decision aid developed for breast cancer risk-reducing discussions and interventions in the WISDOM study. Cancer Research. 2020 Feb 15; 80(4_Supplement):p5-08-23-p5-08-23. Keane KH, Huilgol HY, Shibley SW, Shieh SY, Goodman GD, Tice TJ, Belkora BJ, Sepucha SK, Ozzane OE, Fiscalini FA, Esserman EL. .
      View in: Publisher Site   Mentions:
    57. Abstract P5-08-01: Breast cancer risk thresholds as a predictor of chemoprevention uptake in the Athena Breast Health Network. Cancer Research. 2020 Feb 15; 80(4_Supplement):p5-08-01-p5-08-01. Huilgol HY, Keane KH, Shieh SY, Tice TJ, Ziv ZE, Madlensky ML, Sabacan SL, Acerbi AI, Che CM, Fiscalini FA, Anton-Culver AH, Borowsky BA, Hunt HS, Naeim NA, Parker PB, van 't Veer vL. .
      View in: Publisher Site   Mentions:
    58. Abstract P2-10-05: A breast cancer multi-racial/ethnic polygenic risk score for improved personalized breast cancer screening. Cancer Research. 2020 Feb 15; 80(4_Supplement):p2-10-05-p2-10-05. Theiner TS, Hu HD, Huntsman HS, Shieh SY, Fejerman FL, Acerbi AI, Sawyer SS, Kendall KP, Zheng ZW, Huo HD, Olopade OO, Haiman HC, Kerlikowske KK, Cummings CS, John JE, Torres-Mejia TG, Kushi KL, Wolf WD, Tice TJ, Pearce PD, Esserman EL, van ‘t Veer vL, Ziv ZE. .
      View in: Publisher Site   Mentions:
    59. α7-Nicotine acetylcholine receptor mediated nicotine induced cell survival and cisplatin resistance in oral cancer. Arch Oral Biol. 2020 Mar; 111:104653. Hsu CC, Tsai KY, Su YF, Chien CY, Chen YC, Wu YC, Liu SY, Shieh YS. PMID: 31935534.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    60. Abstract 2419: A polygenic risk score predicts breast cancer risk in Latinas. Epidemiology. 2019 Jul 1; 2419-2419. Shieh SY, Fejerman FL, Sawyer SS, Hu HD, Huntsman HS, John JE, Kushi KL, Torres-Mejia TG, Weitzel WJ, Haiman HC, Ziv ZE, Neuhausen NS. .
      View in: Publisher Site   Mentions:
    61. Abstract 3361: A prescription for new trial designs for drug development focused on the neoadjuvant setting: Save lives, resources, and time. Regulatory Science and Policy. 2019 Jul 1; 3361-3361. Karlsson KA, Shieh SY, Dempsey DA, Yau YC, Dmichele DA, Yes YD, Veer VL, Hylton HN, Eklund EM, Esserman EL. .
      View in: Publisher Site   Mentions:
    62. Macrophage phenotypes and Gas6/Axl signaling in apical lesions. J Dent Sci. 2019 Sep; 14(3):281-287. Chen SY, Chiang CF, Chiu KC, Cheng CW, Huang SM, Chen PH, Chen CY, Shieh YS. PMID: 31528256; PMCID: PMC6739459.
      View in: PubMed   Mentions: 14  
    63. Body mass index, mammographic density, and breast cancer risk by estrogen receptor subtype. Breast Cancer Res. 2019 04 03; 21(1):48. Shieh Y, Scott CG, Jensen MR, Norman AD, Bertrand KA, Pankratz VS, Brandt KR, Visscher DW, Shepherd JA, Tamimi RM, Vachon CM, Kerlikowske K. PMID: 30944014; PMCID: PMC6448282.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    64. A response to "Personalised medicine and population health: breast and ovarian cancer". Hum Genet. 2019 Mar; 138(3):287-289. Antoniou A, Anton-Culver H, Borowsky A, Broeders M, Brooks J, Chiarelli A, Chiquette J, Cuzick J, Delaloge S, Devilee P, Dorval M, Easton D, Eisen A, Eklund M, Eloy L, Esserman L, Garcia-Closas M, Goldgar D, Hall P, Knoppers BM, Kraft P, La Croix A, Madalensky L, Mavaddat N, Mittman N, Nabi H, Olopade O, Pashayan N, Schmidt M, Shieh Y, Simard J, Stover-Fiscallini A, Tice JA, Van't Veer L, Wenger N, Wolfson M, Yau C, Ziv E. PMID: 30810870; PMCID: PMC8207533.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    65. OCT4B mediates hypoxia-induced cancer dissemination. Oncogene. 2019 02; 38(7):1093-1105. Lin SC, Chung CH, Chung CH, Kuo MH, Hsieh CH, Chiu YF, Shieh YS, Chou YT, Wu CW. PMID: 30209362.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    66. Relationship of the Incidence of C-shaped Root Canal Configurations of Mandibular First Premolars with Distolingual Roots in Mandibular First Molars in a Taiwanese Population: A Cone-beam Computed Tomographic Study. J Endod. 2018 Oct; 44(10):1492-1499.e1. Wu YC, Cathy Tsai YW, Cheng WC, Weng PW, Su CC, Chiang HS, Chung MP, Chung CH, Shieh YS, Huang RY. PMID: 30144984.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    67. A breast cancer risk model as a predictor of interval cancer rate and tumor characteristics. Journal of Clinical Oncology. 2018 May 20; 36(15_suppl):1506-1506. Dreher DN, Acerbi AI, Hadeler HE, Shieh SY, Melisko MM, Investigators and Advocates IA, Esserman EL, van 't Veer vL. .
      View in: Publisher Site   Mentions:
    68. The Presence of Distolingual Root in Mandibular First Molars Is Correlated with Complicated Root Canal Morphology of Mandibular Central Incisors: A Cone-beam Computed Tomographic Study in a Taiwanese Population. J Endod. 2018 May; 44(5):711-716.e1. Wu YC, Cheng WC, Weng PW, Chung MP, Su CC, Chiang HS, Tsai YC, Chung CH, Shieh YS, Huang RY. PMID: 29499856.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    69. Abstract P3-09-02: Risk stratification using clinical risk factors and genetic variants in a personalized screening trial. Poster Session Abstracts. 2018 Feb 15; p3-09-02-p3-09-02. Shieh SY, Ziv ZE, Eklund EM, Sabacan SL, Firouzian FR, Madlensky ML, Anton-Culver AH, Borowsky BA, LaCroix LA, Naeim NA, Parker PB, van't Veer vL, Esserman EL, Tice TJ. .
      View in: Publisher Site   Mentions:
    70. Periodontal status of tooth adjacent to implant with peri-implantitis. J Dent. 2018 03; 70:104-109. Sung CE, Chiang CY, Chiu HC, Shieh YS, Lin FG, Fu E. PMID: 29326047.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansPHPublic Health
    71. Complicated Root Canal Morphology of Mandibular Lateral Incisors Is Associated with the Presence of Distolingual Root in Mandibular First Molars: A Cone-beam Computed Tomographic Study in a Taiwanese Population. J Endod. 2018 Jan; 44(1):73-79.e1. Wu YC, Cheng WC, Chung MP, Su CC, Weng PW, Cathy Tsai YW, Chiang HS, Yeh HW, Chung CH, Shieh YS, Huang RY. PMID: 29079050.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    72. The WISDOM Study: breaking the deadlock in the breast cancer screening debate. NPJ Breast Cancer. 2017; 3:34. Esserman LJ, WISDOM Study and Athena Investigators. PMID: 28944288; PMCID: PMC5597574.
      View in: PubMed   Mentions: 134  
    73. Joint relative risks for estrogen receptor-positive breast cancer from a clinical model, polygenic risk score, and sex hormones. Breast Cancer Res Treat. 2017 Nov; 166(2):603-612. Shieh Y, Hu D, Ma L, Huntsman S, Gard CC, Leung JWT, Tice JA, Ziv E, Kerlikowske K, Cummings SR. PMID: 28791495; PMCID: PMC5669824.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    74. A novel potential biomarker for metabolic syndrome in Chinese adults: Circulating protein disulfide isomerase family A, member 4. PLoS One. 2017; 12(6):e0179963. Chien CY, Hung YJ, Shieh YS, Hsieh CH, Lu CH, Lin FH, Su SC, Lee CH. PMID: 28650993; PMCID: PMC5484513.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    75. Dental restorative treatment expenditure and resource utilization in patients with chronic kidney disease: A nationwide population-based study. J Dent Sci. 2017 Sep; 12(3):275-282. Huang RY, Lin YF, Kao SY, Shieh YS, Chen JS. PMID: 30895062; PMCID: PMC6400004.
      View in: PubMed   Mentions: 2  
    76. Metformin-treated cancer cells modulate macrophage polarization through AMPK-NF-κB signaling. Oncotarget. 2017 Mar 28; 8(13):20706-20718. Chiang CF, Chao TT, Su YF, Hsu CC, Chien CY, Chiu KC, Shiah SG, Lee CH, Liu SY, Shieh YS. PMID: 28157701; PMCID: PMC5400538.
      View in: PubMed   Mentions: 97     Fields:    Translation:HumansAnimalsCells
    77. Low-Dose CT Scan for Lung Cancer Screening: Clinical and Coding Considerations. Chest. 2017 07; 152(1):204-209. Shieh Y, Bohnenkamp M. PMID: 28336485.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    78. Abstract P5-09-05: A model with polygenic risk score and mammographic density predicts interval cancers. Poster Session Abstracts. 2017 Feb 15; p5-09-05-p5-09-05. Shieh SY, Hu HD, Huntsman HS, Ma ML, Gard GC, Leung LJ, Tice TJ, Cummings CS, Kerlikowske KK, Ziv ZE. .
      View in: Publisher Site   Mentions:
    79. Breast Cancer Screening in the Precision Medicine Era: Risk-Based Screening in a Population-Based Trial. J Natl Cancer Inst. 2017 01; 109(5). Shieh Y, Eklund M, Madlensky L, Sawyer SD, Thompson CK, Stover Fiscalini A, Ziv E, Van't Veer LJ, Esserman LJ, Tice JA, Athena Breast Health Network Investigators. PMID: 28130475.
      View in: PubMed   Mentions: 121     Fields:    Translation:Humans
    80. Parathyroid Hormone-Like Hormone is a Poor Prognosis Marker of Head and Neck Cancer and Promotes Cell Growth via RUNX2 Regulation. Sci Rep. 2017 01 25; 7:41131. Chang WM, Lin YF, Su CY, Peng HY, Chang YC, Hsiao JR, Chen CL, Chang JY, Shieh YS, Hsiao M, Shiah SG. PMID: 28120940; PMCID: PMC5264159.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    81. Dysregulation of RUNX2/Activin-A Axis upon miR-376c Downregulation Promotes Lymph Node Metastasis in Head and Neck Squamous Cell Carcinoma. Cancer Res. 2016 12 15; 76(24):7140-7150. Chang WM, Lin YF, Su CY, Peng HY, Chang YC, Lai TC, Wu GH, Hsu YM, Chi LH, Hsiao JR, Chen CL, Chang JY, Shieh YS, Hsiao M, Shiah SG. PMID: 27760788.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    82. Breast cancer risk prediction using a clinical risk model and polygenic risk score. Breast Cancer Res Treat. 2016 Oct; 159(3):513-25. Shieh Y, Hu D, Ma L, Huntsman S, Gard CC, Leung JW, Tice JA, Vachon CM, Cummings SR, Kerlikowske K, Ziv E. PMID: 27565998; PMCID: PMC5033764.
      View in: PubMed   Mentions: 94     Fields:    Translation:Humans
    83. Population-based screening for cancer: hope and hype. Nat Rev Clin Oncol. 2016 09; 13(9):550-65. Shieh Y, Eklund M, Sawaya GF, Black WC, Kramer BS, Esserman LJ. PMID: 27071351; PMCID: PMC6585415.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansPHPublic Health
    84. Triptolide represses oral cancer cell proliferation, invasion, migration, and angiogenesis in co-inoculation with U937 cells. Clin Oral Investig. 2017 Jan; 21(1):419-427. Yang CY, Lin CK, Lin GJ, Hsieh CC, Huang SH, Ma KH, Shieh YS, Sytwu HK, Chen YW. PMID: 27073100; PMCID: PMC5203829.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    85. Detection of ductal carcinoma in situ and subsequent interval cancers. BMJ. 2016 Feb 01; 352:i551. Shieh Y, Eklund M, Esserman L. PMID: 26834245.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    86. Polarization of tumor-associated macrophages and Gas6/Axl signaling in oral squamous cell carcinoma. Oral Oncol. 2015 Jul; 51(7):683-9. Chiu KC, Lee CH, Liu SY, Chou YT, Huang RY, Huang SM, Shieh YS. PMID: 25910588.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    87. Downregulated miR329 and miR410 promote the proliferation and invasion of oral squamous cell carcinoma by targeting Wnt-7b. Cancer Res. 2014 Dec 15; 74(24):7560-72. Shiah SG, Hsiao JR, Chang WM, Chen YW, Jin YT, Wong TY, Huang JS, Tsai ST, Hsu YM, Chou ST, Yen YC, Jiang SS, Shieh YS, Chang IS, Hsiao M, Chang JY. PMID: 25351956.
      View in: PubMed   Mentions: 84     Fields:    Translation:HumansAnimalsCells
    88. A retrospective case-control analysis of the outpatient expenditures for western medicine and dental treatment modalities in CKD patients in Taiwan. PLoS One. 2014; 9(2):e88418. Huang RY, Lin YF, Kao SY, Shieh YS, Chen JS. PMID: 24533085; PMCID: PMC3922810.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    89. Risk assessment of inferior alveolar nerve injury for immediate implant placement in the posterior mandible: a virtual implant placement study. J Dent. 2014 Mar; 42(3):263-70. Lin MH, Mau LP, Cochran DL, Shieh YS, Huang PH, Huang RY. PMID: 24394585.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    90. Impact of mammographic screening on the detection of good and poor prognosis breast cancers. Breast Cancer Res Treat. 2011 Dec; 130(3):725-34. Esserman LJ, Shieh Y, Rutgers EJ, Knauer M, Retèl VP, Mook S, Glas AM, Moore DH, Linn S, van Leeuwen FE, van 't Veer LJ. PMID: 21892702; PMCID: PMC5646368.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    91. Characterizing the impact of 25 years of DCIS treatment. Breast Cancer Res Treat. 2011 Aug; 129(1):165-73. Ozanne EM, Shieh Y, Barnes J, Bouzan C, Hwang ES, Esserman LJ. PMID: 21390494.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansPHPublic Health
    92. Effect of screening on the detection of good and poor prognosis breast cancers. Journal of Clinical Oncology. 2010 May 20; 28(15_suppl):1520-1520. Shieh SY, Esserman EL, Rutgers RE, Knauer KM, Retel RV, Mook MS, Glas GA, Linn LS, van Leeuwen vF, van't Veer vL. .
      View in: Publisher Site   Mentions:
    93. Rethinking screening for breast cancer and prostate cancer. JAMA. 2009 Oct 21; 302(15):1685-92. Esserman L, Shieh Y, Thompson I. PMID: 19843904.
      View in: PubMed   Mentions: 197     Fields:    Translation:HumansPHPublic Health
    94. A role for biomarkers in the screening and diagnosis of breast cancer in younger women. Expert Rev Mol Diagn. 2007 Sep; 7(5):533-44. Esserman LJ, Shieh Y, Park JW, Ozanne EM. PMID: 17892362.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
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