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John Witte, PhD, MS

Title(s)Professor, Epidemiology & Biostatistics
SchoolSchool of Medicine
Address1450 Third St
San Francisco CA 94158
Phone415-514-8114
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    Collapse Biography 
    Collapse Education and Training
    UC Santa BarbaraBS6/1986Mathematical Sciences
    UC BerkeleyMS5/1988Engineering
    UC Los AngelesPhD6/1994Epidemiology
    Univ. Southern California, Los AngelesPost-doc10/1995Biostatistics

    Collapse Overview 
    Collapse Overview
    I have extensive experience in the design and statistical analysis of genetic epidemiologic projects. My research program encompasses a synthesis of methodological and applied genetic epidemiology, with the overall aim of deciphering the mechanisms underlying complex diseases and traits. I have developed widely used methods and software for studying rare genetic variants, pathways, interactions, and genome-wide association studies. I am applying these methods to studies of cancer, birth defects, and pharmacogenomics. Current projects in my lab include developing methods for effectively evaluating pleiotropy, determining the germline and somatic basis of prostate cancer risk and aggressiveness, and detecting genes that impact drug / treatment response. We have also recently been evaluating the use of cell free DNA (liquid biopsies) for prediction of prostate cancer risk and progression. In addition, I direct an NIH-Funded post-Doctoral training grant in Genetic Cancer Epidemiology, and have mentored over 40 pre- and post-doctoral fellows.

    Collapse Research 
    Collapse Research Activities and Funding
    Precision Prostate Cancer Screening with Genetically Adjusted Prostate-Specific Antigen Levels
    NIH/NCI R01CA241410Apr 1, 2020 - Mar 31, 2024
    Role: Principal Investigator
    Genome-wide Pleiotropy Scan across Multiple Cancers
    NIH/NCI R01CA201358Aug 1, 2016 - Jul 31, 2020
    Role: Principal Investigator
    Genomewide Association Study of Prostate Cancer
    NIH/NCI U01CA127298Sep 18, 2008 - Aug 31, 2014
    Role: Principal Investigator
    Training in the Molecular & Genetic Epidemiology of Cancer
    NIH/NCI T32CA112355Dec 1, 2004 - Jun 30, 2025
    Role: Principal Investigator
    Training in Molecular& Genetic Epidemiology of Cancer
    NIH/NCI R25CA112355Dec 1, 2004 - Aug 31, 2019
    Role: Principal Investigator
    Androgen Pathway Factors and Prostate Cancer
    NIH/NCI R01CA094211Jul 15, 2002 - Jun 30, 2007
    Role: Principal Investigator
    Computational Genomic Epidemiology of Cancer (CoGEC) Training Program
    NIH/NCI R25CA094186Dec 1, 2001 - Jul 31, 2017
    Role: Co-Principal Investigator
    Genetic Epidemiology of Prostate Cancer Risk and Progression
    NIH/NCI R01CA088164Sep 1, 2000 - Nov 30, 2011
    Role: Principal Investigator
    Pharmacogenomics of Membrane Transporters
    NIH U19GM061390Apr 1, 2000 - Jun 30, 2015
    Role: Co-Investigator
    Cancer Center Support Grant
    NIH/NCI P30CA082103Aug 5, 1999 - Sep 29, 2012
    Role: Co-Investigator
    HIERARCHICAL MODELING IN CANCER RESEARCH
    NIH/NCI R29CA073270Jul 1, 1996 - Jun 30, 2001
    Role: Principal Investigator
    Human Genetic Analysis Resource
    NIH P41RR003655Sep 30, 1987 - Jul 31, 2012
    Role: Co-Investigator

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    Collapse In The News
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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts. Nat Commun. 2020 Sep 04; 11(1):4423. Rashkin SR, Graff RE, Kachuri L, Thai KK, Alexeeff SE, Blatchins MA, Cavazos TB, Corley DA, Emami NC, Hoffman JD, Jorgenson E, Kushi LH, Meyers TJ, Van Den Eeden SK, Ziv E, Habel LA, Hoffmann TJ, Sakoda LC, Witte JS. PMID: 32887889.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    2. The competing risk of death and selective survival cannot fully explain the inverse cancer-dementia association. Alzheimers Dement. 2020 Sep 03. Hayes-Larson E, Ackley SF, Zimmerman SC, Ospina-Romero M, Glymour MM, Graff RE, Witte JS, Kobayashi LC, Mayeda ER. PMID: 32881307.
      View in: PubMed   Mentions:    Fields:    
    3. A machine learning approach to optimizing cell-free DNA sequencing panels: with an application to prostate cancer. BMC Cancer. 2020 Aug 28; 20(1):820. Cario CL, Chen E, Leong L, Emami NC, Lopez K, Tenggara I, Simko JP, Friedlander TW, Li PS, Paris PL, Carroll PR, Witte JS. PMID: 32859160.
      View in: PubMed   Mentions:    Fields:    
    4. Congenital diaphragmatic hernia and maternal dietary nutrient pathways and diet quality. Birth Defects Res. 2020 Aug 03. Carmichael SL, Ma C, Witte JS, Yang W, Rasmussen SA, Brunelli L, Nestoridi E, Shaw GM, Feldkamp ML. PMID: 32744808.
      View in: PubMed   Mentions:    Fields:    
    5. Age-of-onset information helps identify 76 genetic variants associated with allergic disease. PLoS Genet. 2020 06; 16(6):e1008725. Ferreira MAR, Vonk JM, Baurecht H, Marenholz I, Tian C, Hoffman JD, Helmer Q, Tillander A, Ullemar V, Lu Y, Grosche S, Rüschendorf F, Granell R, Brumpton BM, Fritsche LG, Bhatta L, Gabrielsen ME, Nielsen JB, Zhou W, Hveem K, Langhammer A, Holmen OL, Løset M, Abecasis GR, Willer CJ, Emami NC, Cavazos TB, Witte JS, Szwajda A, Hinds DA, Hübner N, Weidinger S, Magnusson PK, Jorgenson E, Karlsson R, Paternoster L, Boomsma DI, Almqvist C, Lee YA, Koppelman GH. PMID: 32603359.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Genomewide Meta-Analysis Validates a Role for S1PR1 in Microtubule Targeting Agent-Induced Sensory Peripheral Neuropathy. Clin Pharmacol Ther. 2020 Jun 20. Chua KC, Xiong C, Ho C, Mushiroda T, Jiang C, Mulkey F, Lai D, Schneider BP, Rashkin SR, Witte JS, Friedman PN, Ratain MJ, McLeod HL, Rugo HS, Shulman LN, Kubo M, Owzar K, Kroetz DL. PMID: 32562552.
      View in: PubMed   Mentions:    Fields:    
    7. The Association Between Cancer and Spousal Rate of Memory Decline: A Negative Control Study to Evaluate (Unmeasured) Social Confounding of the Cancer-memory Relationship. Alzheimer Dis Assoc Disord. 2020 Jun 19. Ospina-Romero M, Brenowitz WD, Glymour MM, Mayeda ER, Graff RE, Witte JS, Ackley SF, Lu KP, Kobayashi LC. PMID: 32568784.
      View in: PubMed   Mentions:    Fields:    
    8. The landscape of host genetic factors involved in infection to common viruses and SARS-CoV-2. medRxiv. 2020 May 30. Kachuri L, Francis SS, Morrison M, Bossé Y, Cavazos TB, Rashkin SR, Ziv E, Witte JS. PMID: 32511533.
      View in: PubMed   Mentions:
    9. Association between inflammatory bowel disease and prostate cancer: A large-scale, prospective, population-based study. Int J Cancer. 2020 Nov 15; 147(10):2735-2742. Meyers TJ, Weiner AB, Graff RE, Desai AS, Cooley LF, Catalona WJ, Hanauer SB, Wu JD, Schaeffer EM, Abdulkadir SA, Kundu SD, Witte JS. PMID: 32399975.
      View in: PubMed   Mentions:    Fields:    
    10. Efficient Estimation and Applications of Cross-Validated Genetic Predictions to Polygenic Risk Scores and Linear Mixed Models. J Comput Biol. 2020 Apr; 27(4):599-612. Mefford J, Park D, Zheng Z, Ko A, Ala-Korpela M, Laakso M, Pajukanta P, Yang J, Witte J, Zaitlen N. PMID: 32077750.
      View in: PubMed   Mentions: 2     Fields:    
    11. A meta-analysis of genome-wide association studies of multiple myeloma among men and women of African ancestry. Blood Adv. 2020 Jan 14; 4(1):181-190. Du Z, Weinhold N, Song GC, Rand KA, Van Den Berg DJ, Hwang AE, Sheng X, Hom V, Ailawadhi S, Nooka AK, Singhal S, Pawlish K, Peters ES, Bock C, Mohrbacher A, Stram A, Berndt SI, Blot WJ, Casey G, Stevens VL, Kittles R, Goodman PJ, Diver WR, Hennis A, Nemesure B, Klein EA, Rybicki BA, Stanford JL, Witte JS, Signorello L, John EM, Bernstein L, Stroup AM, Stephens OW, Zangari M, Van Rhee F, Olshan A, Zheng W, Hu JJ, Ziegler R, Nyante SJ, Ingles SA, Press MF, Carpten JD, Chanock SJ, Mehta J, Colditz GA, Wolf J, Martin TG, Tomasson M, Fiala MA, Terebelo H, Janakiraman N, Kolonel L, Anderson KC, Le Marchand L, Auclair D, Chiu BC, Ziv E, Stram D, Vij R, Bernal-Mizrachi L, Morgan GJ, Zonder JA, Huff CA, Lonial S, Orlowski RZ, Conti DV, Haiman CA, Cozen W. PMID: 31935283.
      View in: PubMed   Mentions:    Fields:    
    12. Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility. Nat Commun. 2020 01 07; 11(1):27. Kachuri L, Johansson M, Rashkin SR, Graff RE, Bossé Y, Manem V, Caporaso NE, Landi MT, Christiani DC, Vineis P, Liu G, Scelo G, Zaridze D, Shete SS, Albanes D, Aldrich MC, Tardón A, Rennert G, Chen C, Goodman GE, Doherty JA, Bickeböller H, Field JK, Davies MP, Dawn Teare M, Kiemeney LA, Bojesen SE, Haugen A, Zienolddiny S, Lam S, Le Marchand L, Cheng I, Schabath MB, Duell EJ, Andrew AS, Manjer J, Lazarus P, Arnold S, McKay JD, Emami NC, Warkentin MT, Brhane Y, Obeidat M, Martin RM, Relton C, Davey Smith G, Haycock PC, Amos CI, Brennan P, Witte JS, Hung RJ. PMID: 31911640.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. Development and pilot evaluation of a personalized decision support intervention for low risk prostate cancer patients. Cancer Med. 2020 01; 9(1):125-132. Belkora J, Chan JM, Cooperberg MR, Neuhaus J, Stupar L, Weinberg T, Broering JM, Tenggara I, Cowan JE, Rosenfeld S, Kenfield SA, Van Blarigan EL, Simko JP, Witte J, Carroll PR. PMID: 31714037.
      View in: PubMed   Mentions:    Fields:    
    14. Germline testing in those at risk of prostate cancer. Can J Urol. 2019 Oct; 26(5 Suppl 2):31-33. Carroll PR, Witte JS, Parsons JK. PMID: 31629425.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. Author Correction: Association of imputed prostate cancer transcriptome with disease risk reveals novel mechanisms. Nat Commun. 2019 Aug 28; 10(1):3948. Emami NC, Kachuri L, Meyers TJ, Das R, Hoffman JD, Hoffmann TJ, Hu D, Shan J, Feng FY, Ziv E, Van Den Eeden SK, Witte JS. PMID: 31462633.
      View in: PubMed   Mentions:    Fields:    
    16. Association of imputed prostate cancer transcriptome with disease risk reveals novel mechanisms. Nat Commun. 2019 07 15; 10(1):3107. Emami NC, Kachuri L, Meyers TJ, Das R, Hoffman JD, Hoffmann TJ, Hu D, Shan J, Feng FY, Ziv E, Van Den Eeden SK, Witte JS. PMID: 31308362.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    17. A genome-wide association study of prostate cancer in Latinos. Int J Cancer. 2020 04 01; 146(7):1819-1826. Du Z, Hopp H, Ingles SA, Huff C, Sheng X, Weaver B, Stern M, Hoffmann TJ, John EM, Van Den Eeden SK, Strom S, Leach RJ, Thompson IM, Witte JS, Conti DV, Haiman CA. PMID: 31226226.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    18. Methods for measuring financial toxicity after cancer diagnosis and treatment: a systematic review and its implications. Ann Oncol. 2019 07 01; 30(7):1061-1070. Witte J, Mehlis K, Surmann B, Lingnau R, Damm O, Greiner W, Winkler EC. PMID: 31046080.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    19. Identification of Novel Susceptibility Loci and Genes for Prostate Cancer Risk: A Transcriptome-Wide Association Study in Over 140,000 European Descendants. Cancer Res. 2019 07 01; 79(13):3192-3204. Wu L, Wang J, Cai Q, Cavazos TB, Emami NC, Long J, Shu XO, Lu Y, Guo X, Bauer JA, Pasaniuc B, Penney KL, Freedman ML, Kote-Jarai Z, Witte JS, Haiman CA, Eeles RA, Zheng W. PMID: 31101764.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    20. Samasy: an automated system for sample selection and robotic transfer. Biotechniques. 2018 12; 65(6):357-360. Cario CL, Witte JS. PMID: 30477330.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    21. A Pharmacogenetic Prediction Model of Progression-Free Survival in Breast Cancer using Genome-Wide Genotyping Data from CALGB 40502 (Alliance). Clin Pharmacol Ther. 2019 03; 105(3):738-745. Rashkin SR, Chua KC, Ho C, Mulkey F, Jiang C, Mushiroda T, Kubo M, Friedman PN, Rugo HS, McLeod HL, Ratain MJ, Castillos F, Naughton M, Overmoyer B, Toppmeyer D, Witte JS, Owzar K, Kroetz DL. PMID: 30260474.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCTClinical Trials
    22. Newborn Metabolic Profile Associated with Hyperbilirubinemia With and Without Kernicterus. Clin Transl Sci. 2019 01; 12(1):28-38. McCarthy ME, Oltman SP, Baer RJ, Ryckman KK, Rogers EE, Steurer-Muller MA, Witte JS, Jelliffe-Pawlowski LL. PMID: 30369069.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    23. Personalized Prostate Cancer Screening Based on a Single Midlife Prostate-specific Antigen Measurement. Eur Urol. 2019 03; 75(3):408-409. Graff RE, Kachuri L, Witte JS. PMID: 30268658.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    24. Detecting Rare Mutations with Heterogeneous Effects Using a Family-Based Genetic Random Field Method. Genetics. 2018 10; 210(2):463-476. Li M, He Z, Tong X, Witte JS, Lu Q. PMID: 30104420.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    25. Two HLA Class II Gene Variants Are Independently Associated with Pediatric Osteosarcoma Risk. Cancer Epidemiol Biomarkers Prev. 2018 10; 27(10):1151-1158. Zhang C, Wiemels JL, Hansen HM, Gonzalez-Maya J, Endicott AA, de Smith AJ, Smirnov IV, Witte JS, Morimoto LM, Metayer C, Walsh KM. PMID: 30038050.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    26. Quantitative Spatial Profiling of PD-1/PD-L1 Interaction and HLA-DR/IDO-1 Predicts Improved Outcomes of Anti-PD-1 Therapies in Metastatic Melanoma. Clin Cancer Res. 2018 11 01; 24(21):5250-5260. Johnson DB, Bordeaux J, Kim JY, Vaupel C, Rimm DL, Ho TH, Joseph RW, Daud AI, Conry RM, Gaughan EM, Hernandez-Aya LF, Dimou A, Funchain P, Smithy J, Witte JS, McKee SB, Ko J, Wrangle JM, Dabbas B, Tangri S, Lameh J, Hall J, Markowitz J, Balko JM, Dakappagari N. PMID: 30021908.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    27. Orchid: a novel management, annotation and machine learning framework for analyzing cancer mutations. Bioinformatics. 2018 03 15; 34(6):936-942. Cario CL, Witte JS. PMID: 29106441.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    28. An efficient Bayesian meta-analysis approach for studying cross-phenotype genetic associations. PLoS Genet. 2018 02; 14(2):e1007139. Majumdar A, Haldar T, Bhattacharya S, Witte JS. PMID: 29432419.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    29. A Canadian genome-wide association study and meta-analysis confirm HLA as a risk factor for peanut allergy independent of asthma. J Allergy Clin Immunol. 2018 04; 141(4):1513-1516. Asai Y, Eslami A, van Ginkel CD, Akhabir L, Wan M, Yin D, Ellis G, Ben-Shoshan M, Marenholz I, Martino D, Ferreira MA, Allen K, Mazer B, de Groot H, de Jong NW, Gerth van Wijk R, Dubois AEJ, Grosche S, Ashley S, Rüschendorf F, Kalb B, Beyer K, Nöthen MM, Lee YA, Chin R, Cheuk S, Hoffman J, Jorgensen E, Witte JS, Melles RB, Hong X, Wang X, Hui J, Musk AWB, Hunter M, James AL, Koppelman GH, Sandford AJ, Clarke AE, Daley D. PMID: 29325868.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    30. Identification of Pleiotropic Cancer Susceptibility Variants from Genome-Wide Association Studies Reveals Functional Characteristics. Cancer Epidemiol Biomarkers Prev. 2018 01; 27(1):75-85. Wu YH, Graff RE, Passarelli MN, Hoffman JD, Ziv E, Hoffmann TJ, Witte JS. PMID: 29150481.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    31. Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology. Nat Genet. 2017 Dec; 49(12):1752-1757. Ferreira MA, Vonk JM, Baurecht H, Marenholz I, Tian C, Hoffman JD, Helmer Q, Tillander A, Ullemar V, van Dongen J, Lu Y, Rüschendorf F, Esparza-Gordillo J, Medway CW, Mountjoy E, Burrows K, Hummel O, Grosche S, Brumpton BM, Witte JS, Hottenga JJ, Willemsen G, Zheng J, Rodríguez E, Hotze M, Franke A, Revez JA, Beesley J, Matheson MC, Dharmage SC, Bain LM, Fritsche LG, Gabrielsen ME, Balliu B, Nielsen JB, Zhou W, Hveem K, Langhammer A, Holmen OL, Løset M, Abecasis GR, Willer CJ, Arnold A, Homuth G, Schmidt CO, Thompson PJ, Martin NG, Duffy DL, Novak N, Schulz H, Karrasch S, Gieger C, Strauch K, Melles RB, Hinds DA, Hübner N, Weidinger S, Magnusson PKE, Jansen R, Jorgenson E, Lee YA, Boomsma DI, Almqvist C, Karlsson R, Koppelman GH, Paternoster L. PMID: 29083406.
      View in: PubMed   Mentions: 49     Fields:    Translation:Humans
    32. Genome-wide association study and meta-analysis in multiple populations identifies new loci for peanut allergy and establishes C11orf30/EMSY as a genetic risk factor for food allergy. J Allergy Clin Immunol. 2018 03; 141(3):991-1001. Asai Y, Eslami A, van Ginkel CD, Akhabir L, Wan M, Ellis G, Ben-Shoshan M, Martino D, Ferreira MA, Allen K, Mazer B, de Groot H, de Jong NW, Gerth van Wijk RN, Dubois AEJ, Chin R, Cheuk S, Hoffman J, Jorgensen E, Witte JS, Melles RB, Hong X, Wang X, Hui J, Musk AWB, Hunter M, James AL, Koppelman GH, Sandford AJ, Clarke AE, Daley D. PMID: 29030101.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    33. Update on the State of the Science for Analytical Methods for Gene-Environment Interactions. Am J Epidemiol. 2017 Oct 01; 186(7):762-770. Gauderman WJ, Mukherjee B, Aschard H, Hsu L, Lewinger JP, Patel CJ, Witte JS, Amos C, Tai CG, Conti D, Torgerson DG, Lee S, Chatterjee N. PMID: 28978192.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    34. Current Challenges and New Opportunities for Gene-Environment Interaction Studies of Complex Diseases. Am J Epidemiol. 2017 Oct 01; 186(7):753-761. McAllister K, Mechanic LE, Amos C, Aschard H, Blair IA, Chatterjee N, Conti D, Gauderman WJ, Hsu L, Hutter CM, Jankowska MM, Kerr J, Kraft P, Montgomery SB, Mukherjee B, Papanicolaou GJ, Patel CJ, Ritchie MD, Ritz BR, Thomas DC, Wei P, Witte JS. PMID: 28978193.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    35. Up For A Challenge (U4C): Stimulating innovation in breast cancer genetic epidemiology. PLoS Genet. 2017 09; 13(9):e1006945. Mechanic LE, Lindström S, Daily KM, Sieberts SK, Amos CI, Chen HS, Cox NJ, Dathe M, Feuer EJ, Guertin MJ, Hoffman J, Liu Y, Moore JH, Myers CL, Ritchie MD, Schildkraut J, Schumacher F, Witte JS, Wang W, Williams SM, Gillanders EM. PMID: 28957327.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    36. Two Novel Susceptibility Loci for Prostate Cancer in Men of African Ancestry. J Natl Cancer Inst. 2017 08 01; 109(8). Conti DV, Wang K, Sheng X, Bensen JT, Hazelett DJ, Cook MB, Ingles SA, Kittles RA, Strom SS, Rybicki BA, Nemesure B, Isaacs WB, Stanford JL, Zheng W, Sanderson M, John EM, Park JY, Xu J, Stevens VL, Berndt SI, Huff CD, Wang Z, Yeboah ED, Tettey Y, Biritwum RB, Adjei AA, Tay E, Truelove A, Niwa S, Sellers TA, Yamoah K, Murphy AB, Crawford DC, Gapstur SM, Bush WS, Aldrich MC, Cussenot O, Petrovics G, Cullen J, Neslund-Dudas C, Stern MC, Jarai ZK, Govindasami K, Chokkalingam AP, Hsing AW, Goodman PJ, Hoffmann T, Drake BF, Hu JJ, Clark PE, Van Den Eeden SK, Blanchet P, Fowke JH, Casey G, Hennis AJM, Han Y, Lubwama A, Thompson IM, Leach R, Easton DF, Schumacher F, Van den Berg DJ, Gundell SM, Stram A, Wan P, Xia L, Pooler LC, Mohler JL, Fontham ETH, Smith GJ, Taylor JA, Srivastava S, Eeles RA, Carpten J, Kibel AS, Multigner L, Parent ME, Menegaux F, Cancel-Tassin G, Klein EA, Brureau L, Stram DO, Watya S, Chanock SJ, Witte JS, Blot WJ, Henderson BE, Haiman CA. PMID: 29117387.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    37. Non-additive and epistatic effects of HLA polymorphisms contributing to risk of adult glioma. J Neurooncol. 2017 Nov; 135(2):237-244. Zhang C, de Smith AJ, Smirnov IV, Wiencke JK, Wiemels JL, Witte JS, Walsh KM. PMID: 28721485.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    38. Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium. PLoS Genet. 2017 Apr; 13(4):e1006719. Ng MCY, Graff M, Lu Y, Justice AE, Mudgal P, Liu CT, Young K, Yanek LR, Feitosa MF, Wojczynski MK, Rand K, Brody JA, Cade BE, Dimitrov L, Duan Q, Guo X, Lange LA, Nalls MA, Okut H, Tajuddin SM, Tayo BO, Vedantam S, Bradfield JP, Chen G, Chen WM, Chesi A, Irvin MR, Padhukasahasram B, Smith JA, Zheng W, Allison MA, Ambrosone CB, Bandera EV, Bartz TM, Berndt SI, Bernstein L, Blot WJ, Bottinger EP, Carpten J, Chanock SJ, Chen YI, Conti DV, Cooper RS, Fornage M, Freedman BI, Garcia M, Goodman PJ, Hsu YH, Hu J, Huff CD, Ingles SA, John EM, Kittles R, Klein E, Li J, McKnight B, Nayak U, Nemesure B, Ogunniyi A, Olshan A, Press MF, Rohde R, Rybicki BA, Salako B, Sanderson M, Shao Y, Siscovick DS, Stanford JL, Stevens VL, Stram A, Strom SS, Vaidya D, Witte JS, Yao J, Zhu X, Ziegler RG, Zonderman AB, Adeyemo A, Ambs S, Cushman M, Faul JD, Hakonarson H, Levin AM, Nathanson KL, Ware EB, Weir DR, Zhao W, Zhi D, Arnett DK, Grant SFA, Kardia SLR, Oloapde OI, Rao DC, Rotimi CN, Sale MM, Williams LK, Zemel BS, Becker DM, Borecki IB, Evans MK, Harris TB, Hirschhorn JN, Li Y, Patel SR, Psaty BM, Rotter JI, Wilson JG, Bowden DW, Cupples LA, Haiman CA, Loos RJF, North KE. PMID: 28430825.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    39. Investigating the Genetic Architecture of the PR Interval Using Clinical Phenotypes. Circ Cardiovasc Genet. 2017 Apr; 10(2). Mosley JD, Shoemaker MB, Wells QS, Darbar D, Shaffer CM, Edwards TL, Bastarache L, McCarty CA, Thompson W, Chute CG, Jarvik GP, Crosslin DR, Larson EB, Kullo IJ, Pacheco JA, Peissig PL, Brilliant MH, Linneman JG, Witte JS, Denny JC, Roden DM. PMID: 28416512.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    40. Cis-eQTL-based trans-ethnic meta-analysis reveals novel genes associated with breast cancer risk. PLoS Genet. 2017 Mar; 13(3):e1006690. Hoffman JD, Graff RE, Emami NC, Tai CG, Passarelli MN, Hu D, Huntsman S, Hadley D, Leong L, Majumdar A, Zaitlen N, Ziv E, Witte JS. PMID: 28362817.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    41. Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer. Nat Commun. 2017 01 31; 8:14248. Hoffmann TJ, Passarelli MN, Graff RE, Emami NC, Sakoda LC, Jorgenson E, Habel LA, Shan J, Ranatunga DK, Quesenberry CP, Chao CR, Ghai NR, Aaronson D, Presti J, Nordström T, Wang Z, Berndt SI, Chanock SJ, Mosley JD, Klein RJ, Middha M, Lilja H, Melander O, Kvale MN, Kwok PY, Schaefer C, Risch N, Van Den Eeden SK, Witte JS. PMID: 28139693.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    42. Familial Risk and Heritability of Colorectal Cancer in the Nordic Twin Study of Cancer. Clin Gastroenterol Hepatol. 2017 Aug; 15(8):1256-1264. Graff RE, Möller S, Passarelli MN, Witte JS, Skytthe A, Christensen K, Tan Q, Adami HO, Czene K, Harris JR, Pukkala E, Kaprio J, Giovannucci EL, Mucci LA, Hjelmborg JB. PMID: 28130150.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    43. Tissue Sources for Accurate Measurement of Germline DNA Genotypes in Prostate Cancer Patients Treated With Radical Prostatectomy. Prostate. 2017 03; 77(4):425-434. Emami NC, Leong L, Wan E, Van Blarigan EL, Cooperberg MR, Tenggara I, Carroll PR, Chan JM, Witte JS, Simko JP. PMID: 27900799.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    44. Sequence variation in folate pathway genes and risks of human cleft lip with or without cleft palate. . 2016 11; 170(11):2777-2787. Marini NJ, Yang W, Asrani K, Witte JS, Rine J, Lammer EJ, Shaw GM. PMID: 27604992.
      View in: PubMed   Mentions:
    45. Telomere structure and maintenance gene variants and risk of five cancer types. Int J Cancer. 2016 Dec 15; 139(12):2655-2670. Karami S, Han Y, Pande M, Cheng I, Rudd J, Pierce BL, Nutter EL, Schumacher FR, Kote-Jarai Z, Lindstrom S, Witte JS, Fang S, Han J, Kraft P, Hunter DJ, Song F, Hung RJ, McKay J, Gruber SB, Chanock SJ, Risch A, Shen H, Haiman CA, Boardman L, Ulrich CM, Casey G, Peters U, Amin Al Olama A, Berchuck A, Berndt SI, Bezieau S, Brennan P, Brenner H, Brinton L, Caporaso N, Chan AT, Chang-Claude J, Christiani DC, Cunningham JM, Easton D, Eeles RA, Eisen T, Gala M, Gallinger SJ, Gayther SA, Goode EL, Grönberg H, Henderson BE, Houlston R, Joshi AD, Küry S, Landi MT, Le Marchand L, Muir K, Newcomb PA, Permuth-Wey J, Pharoah P, Phelan C, Potter JD, Ramus SJ, Risch H, Schildkraut J, Slattery ML, Song H, Wentzensen N, White E, Wiklund F, Zanke BW, Sellers TA, Zheng W, Chatterjee N, Amos CI, Doherty JA. PMID: 27459707.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    46. A Meta-analysis of Multiple Myeloma Risk Regions in African and European Ancestry Populations Identifies Putatively Functional Loci. Cancer Epidemiol Biomarkers Prev. 2016 12; 25(12):1609-1618. Rand KA, Song C, Dean E, Serie DJ, Curtin K, Sheng X, Hu D, Huff CA, Bernal-Mizrachi L, Tomasson MH, Ailawadhi S, Singhal S, Pawlish K, Peters ES, Bock CH, Stram A, Van Den Berg DJ, Edlund CK, Conti DV, Zimmerman T, Hwang AE, Huntsman S, Graff J, Nooka A, Kong Y, Pregja SL, Berndt SI, Blot WJ, Carpten J, Casey G, Chu L, Diver WR, Stevens VL, Lieber MR, Goodman PJ, Hennis AJ, Hsing AW, Mehta J, Kittles RA, Kolb S, Klein EA, Leske C, Murphy AB, Nemesure B, Neslund-Dudas C, Strom SS, Vij R, Rybicki BA, Stanford JL, Signorello LB, Witte JS, Ambrosone CB, Bhatti P, John EM, Bernstein L, Zheng W, Olshan AF, Hu JJ, Ziegler RG, Nyante SJ, Bandera EV, Birmann BM, Ingles SA, Press MF, Atanackovic D, Glenn MJ, Cannon-Albright LA, Jones B, Tricot G, Martin TG, Kumar SK, Wolf JL, Deming Halverson SL, Rothman N, Brooks-Wilson AR, Rajkumar SV, Kolonel LN, Chanock SJ, Slager SL, Severson RK, Janakiraman N, Terebelo HR, Brown EE, De Roos AJ, Mohrbacher AF, Colditz GA, Giles GG, Spinelli JJ, Chiu BC, Munshi NC, Anderson KC, Levy J, Zonder JA, Orlowski RZ, Lonial S, Camp NJ, Vachon CM, Ziv E, Stram DO, Hazelett DJ, Haiman CA, Cozen W. PMID: 27587788.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    47. Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin. Nat Genet. 2016 09; 48(9):1055-1059. Zhou K, Yee SW, Seiser EL, van Leeuwen N, Tavendale R, Bennett AJ, Groves CJ, Coleman RL, van der Heijden AA, Beulens JW, de Keyser CE, Zaharenko L, Rotroff DM, Out M, Jablonski KA, Chen L, Javorský M, Židzik J, Levin AM, Williams LK, Dujic T, Semiz S, Kubo M, Chien HC, Maeda S, Witte JS, Wu L, Tkác I, Kooy A, van Schaik RHN, Stehouwer CDA, Logie L, Sutherland C, Klovins J, Pirags V, Hofman A, Stricker BH, Motsinger-Reif AA, Wagner MJ, Innocenti F, 't Hart LM, Holman RR, McCarthy MI, Hedderson MM, Palmer CNA, Florez JC, Giacomini KM, Pearson ER. PMID: 27500523.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    48. Erratum to: Hierarchical modeling identifies novel lung cancer susceptibility variants in inflammation pathways among 10,140 cases and 11,012 controls. Hum Genet. 2016 08; 135(8):963. Brenner DR, Brennan P, Boffetta P, Amos CI, Spitz MR, Chen C, Goodman G, Heinrich J, Bickeböller H, Rosenberger A, Risch A, Muley T, McLaughlin JR, Benhamou S, Bouchardy C, Lewinger JP, Witte JS, Chen G, Bull S, Hung RJ. PMID: 27264937.
      View in: PubMed   Mentions:    Fields:    
    49. Host genetic predictors of the kynurenine pathway of tryptophan catabolism among treated HIV-infected Ugandans. AIDS. 2016 07 17; 30(11):1807-15. Lee SA, Mefford JA, Huang Y, Witte JS, Martin JN, Haas DW, Mclaren PJ, Mushiroda T, Kubo M, Byakwaga H, Hunt PW, Kroetz DL. PMID: 27088321.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    50. Determining Which Phenotypes Underlie a Pleiotropic Signal. Genet Epidemiol. 2016 07; 40(5):366-81. Majumdar A, Haldar T, Witte JS. PMID: 27238845.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    51. Association of common genetic variation in the protein C pathway genes with clinical outcomes in acute respiratory distress syndrome. Crit Care. 2016 May 23; 20(1):151. Sapru A, Liu KD, Wiemels J, Hansen H, Pawlikowska L, Poon A, Jorgenson E, Witte JS, Calfee CS, Ware LB, Matthay MA. PMID: 27215212.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    52. Selection and explosive growth alter genetic architecture and hamper the detection of causal rare variants. Genome Res. 2016 07; 26(7):863-73. Uricchio LH, Zaitlen NA, Ye CJ, Witte JS, Hernandez RD. PMID: 27197206.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    53. Identifying genetically driven clinical phenotypes using linear mixed models. Nat Commun. 2016 04 25; 7:11433. Mosley JD, Witte JS, Larkin EK, Bastarache L, Shaffer CM, Karnes JH, Stein CM, Phillips E, Hebbring SJ, Brilliant MH, Mayer J, Ye Z, Roden DM, Denny JC. PMID: 27109359.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    54. Joint effects of genetic variants and residential proximity to pesticide applications on hypospadias risk. Birth Defects Res A Clin Mol Teratol. 2016 Aug; 106(8):653-8. Carmichael SL, Yang W, Ma C, Roberts E, Kegley S, English P, Lammer EJ, Witte JS, Shaw GM. PMID: 27098078.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    55. Testing Allele Transmission of an SNP Set Using a Family-Based Generalized Genetic Random Field Method. Genet Epidemiol. 2016 May; 40(4):341-51. Li M, Li J, He Z, Lu Q, Witte JS, Macleod SL, Hobbs CA, Cleves MA. PMID: 27061818.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    56. Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation. Nat Commun. 2016 Apr 07; 7:10979. Gusev A, Shi H, Kichaev G, Pomerantz M, Li F, Long HW, Ingles SA, Kittles RA, Strom SS, Rybicki BA, Nemesure B, Isaacs WB, Zheng W, Pettaway CA, Yeboah ED, Tettey Y, Biritwum RB, Adjei AA, Tay E, Truelove A, Niwa S, Chokkalingam AP, John EM, Murphy AB, Signorello LB, Carpten J, Leske MC, Wu SY, Hennis AJ, Neslund-Dudas C, Hsing AW, Chu L, Goodman PJ, Klein EA, Witte JS, Casey G, Kaggwa S, Cook MB, Stram DO, Blot WJ, Eeles RA, Easton D, Kote-Jarai Z, Al Olama AA, Benlloch S, Muir K, Giles GG, Southey MC, Fitzgerald LM, Gronberg H, Wiklund F, Aly M, Henderson BE, Schleutker J, Wahlfors T, Tammela TL, Nordestgaard BG, Key TJ, Travis RC, Neal DE, Donovan JL, Hamdy FC, Pharoah P, Pashayan N, Khaw KT, Stanford JL, Thibodeau SN, McDonnell SK, Schaid DJ, Maier C, Vogel W, Luedeke M, Herkommer K, Kibel AS, Cybulski C, Wokolorczyk D, Kluzniak W, Cannon-Albright L, Teerlink C, Brenner H, Dieffenbach AK, Arndt V, Park JY, Sellers TA, Lin HY, Slavov C, Kaneva R, Mitev V, Batra J, Spurdle A, Clements JA, Teixeira MR, Pandha H, Michael A, Paulo P, Maia S, Kierzek A, Conti DV, Albanes D, Berg C, Berndt SI, Campa D, Crawford ED, Diver WR, Gapstur SM, Gaziano JM, Giovannucci E, Hoover R, Hunter DJ, Johansson M, Kraft P, Le Marchand L, Lindström S, Navarro C, Overvad K, Riboli E, Siddiq A, Stevens VL, Trichopoulos D, Vineis P, Yeager M, Trynka G, Raychaudhuri S, Schumacher FR, Price AL, Freedman ML, Haiman CA, Pasaniuc B. PMID: 27052111.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    57. Mutational Landscape of Aggressive Prostate Tumors in African American Men. Cancer Res. 2016 04 01; 76(7):1860-8. Lindquist KJ, Paris PL, Hoffmann TJ, Cardin NJ, Kazma R, Mefford JA, Simko JP, Ngo V, Chen Y, Levin AM, Chitale D, Helfand BT, Catalona WJ, Rybicki BA, Witte JS. PMID: 26921337.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    58. Prostate Cancer Susceptibility in Men of African Ancestry at 8q24. J Natl Cancer Inst. 2016 Jul; 108(7). Han Y, Rand KA, Hazelett DJ, Ingles SA, Kittles RA, Strom SS, Rybicki BA, Nemesure B, Isaacs WB, Stanford JL, Zheng W, Schumacher FR, Berndt SI, Wang Z, Xu J, Rohland N, Reich D, Tandon A, Pasaniuc B, Allen A, Quinque D, Mallick S, Notani D, Rosenfeld MG, Jayani RS, Kolb S, Gapstur SM, Stevens VL, Pettaway CA, Yeboah ED, Tettey Y, Biritwum RB, Adjei AA, Tay E, Truelove A, Niwa S, Chokkalingam AP, John EM, Murphy AB, Signorello LB, Carpten J, Leske MC, Wu SY, Hennis AJM, Neslund-Dudas C, Hsing AW, Chu L, Goodman PJ, Klein EA, Zheng SL, Witte JS, Casey G, Lubwama A, Pooler LC, Sheng X, Coetzee GA, Cook MB, Chanock SJ, Stram DO, Watya S, Blot WJ, Conti DV, Henderson BE, Haiman CA. PMID: 26823525.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    59. A Cross-Cancer Genetic Association Analysis of the DNA Repair and DNA Damage Signaling Pathways for Lung, Ovary, Prostate, Breast, and Colorectal Cancer. Cancer Epidemiol Biomarkers Prev. 2016 Jan; 25(1):193-200. Scarbrough PM, Weber RP, Iversen ES, Brhane Y, Amos CI, Kraft P, Hung RJ, Sellers TA, Witte JS, Pharoah P, Henderson BE, Gruber SB, Hunter DJ, Garber JE, Joshi AD, McDonnell K, Easton DF, Eeles R, Kote-Jarai Z, Muir K, Doherty JA, Schildkraut JM. PMID: 26637267.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    60. Semiparametric Allelic Tests for Mapping Multiple Phenotypes: Binomial Regression and Mahalanobis Distance. Genet Epidemiol. 2015 Dec; 39(8):635-50. Majumdar A, Witte JS, Ghosh S. PMID: 26493781.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    61. MDS-associated somatic mutations and clonal hematopoiesis are common in idiopathic cytopenias of undetermined significance. Blood. 2015 Nov 19; 126(21):2355-61. Kwok B, Hall JM, Witte JS, Xu Y, Reddy P, Lin K, Flamholz R, Dabbas B, Yung A, Al-Hafidh J, Balmert E, Vaupel C, El Hader C, McGinniss MJ, Nahas SA, Kines J, Bejar R. PMID: 26429975.
      View in: PubMed   Mentions: 56     Fields:    Translation:Humans
    62. Strategies for Imputing and Analyzing Rare Variants in Association Studies. Trends Genet. 2015 Oct; 31(10):556-563. Hoffmann TJ, Witte JS. PMID: 26450338.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    63. Cross Cancer Genomic Investigation of Inflammation Pathway for Five Common Cancers: Lung, Ovary, Prostate, Breast, and Colorectal Cancer. J Natl Cancer Inst. 2015 Nov; 107(11). Hung RJ, Ulrich CM, Goode EL, Brhane Y, Muir K, Chan AT, Marchand LL, Schildkraut J, Witte JS, Eeles R, Boffetta P, Spitz MR, Poirier JG, Rider DN, Fridley BL, Chen Z, Haiman C, Schumacher F, Easton DF, Landi MT, Brennan P, Houlston R, Christiani DC, Field JK, Bickeböller H, Risch A, Kote-Jarai Z, Wiklund F, Grönberg H, Chanock S, Berndt SI, Kraft P, Lindström S, Al Olama AA, Song H, Phelan C, Wentzensen N, Peters U, Slattery ML, Sellers TA, Casey G, Gruber SB, Hunter DJ, Amos CI, Henderson B. PMID: 26319099.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    64. Integration of multiethnic fine-mapping and genomic annotation to prioritize candidate functional SNPs at prostate cancer susceptibility regions. Hum Mol Genet. 2015 Oct 01; 24(19):5603-18. Han Y, Hazelett DJ, Wiklund F, Schumacher FR, Stram DO, Berndt SI, Wang Z, Rand KA, Hoover RN, Machiela MJ, Yeager M, Burdette L, Chung CC, Hutchinson A, Yu K, Xu J, Travis RC, Key TJ, Siddiq A, Canzian F, Takahashi A, Kubo M, Stanford JL, Kolb S, Gapstur SM, Diver WR, Stevens VL, Strom SS, Pettaway CA, Al Olama AA, Kote-Jarai Z, Eeles RA, Yeboah ED, Tettey Y, Biritwum RB, Adjei AA, Tay E, Truelove A, Niwa S, Chokkalingam AP, Isaacs WB, Chen C, Lindstrom S, Le Marchand L, Giovannucci EL, Pomerantz M, Long H, Li F, Ma J, Stampfer M, John EM, Ingles SA, Kittles RA, Murphy AB, Blot WJ, Signorello LB, Zheng W, Albanes D, Virtamo J, Weinstein S, Nemesure B, Carpten J, Leske MC, Wu SY, Hennis AJ, Rybicki BA, Neslund-Dudas C, Hsing AW, Chu L, Goodman PJ, Klein EA, Zheng SL, Witte JS, Casey G, Riboli E, Li Q, Freedman ML, Hunter DJ, Gronberg H, Cook MB, Nakagawa H, Kraft P, Chanock SJ, Easton DF, Henderson BE, Coetzee GA, Conti DV, Haiman CA. PMID: 26162851.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    65. Methodological Considerations in Estimation of Phenotype Heritability Using Genome-Wide SNP Data, Illustrated by an Analysis of the Heritability of Height in a Large Sample of African Ancestry Adults. PLoS One. 2015; 10(6):e0131106. Chen F, He J, Zhang J, Chen GK, Thomas V, Ambrosone CB, Bandera EV, Berndt SI, Bernstein L, Blot WJ, Cai Q, Carpten J, Casey G, Chanock SJ, Cheng I, Chu L, Deming SL, Driver WR, Goodman P, Hayes RB, Hennis AJ, Hsing AW, Hu JJ, Ingles SA, John EM, Kittles RA, Kolb S, Leske MC, Millikan RC, Monroe KR, Murphy A, Nemesure B, Neslund-Dudas C, Nyante S, Ostrander EA, Press MF, Rodriguez-Gil JL, Rybicki BA, Schumacher F, Stanford JL, Signorello LB, Strom SS, Stevens V, Van Den Berg D, Wang Z, Witte JS, Wu SY, Yamamura Y, Zheng W, Ziegler RG, Stram AH, Kolonel LN, Le Marchand L, Henderson BE, Haiman CA, Stram DO. PMID: 26125186.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    66. A large multiethnic genome-wide association study of prostate cancer identifies novel risk variants and substantial ethnic differences. Cancer Discov. 2015 Aug; 5(8):878-91. Hoffmann TJ, Van Den Eeden SK, Sakoda LC, Jorgenson E, Habel LA, Graff RE, Passarelli MN, Cario CL, Emami NC, Chao CR, Ghai NR, Shan J, Ranatunga DK, Quesenberry CP, Aaronson D, Presti J, Wang Z, Berndt SI, Chanock SJ, McDonnell SK, French AJ, Schaid DJ, Thibodeau SN, Li Q, Freedman ML, Penney KL, Mucci LA, Haiman CA, Henderson BE, Seminara D, Kvale MN, Kwok PY, Schaefer C, Risch N, Witte JS. PMID: 26034056.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    67. Developments in our understanding of the genetic basis of birth defects. Birth Defects Res A Clin Mol Teratol. 2015 Aug; 103(8):680-91. Webber DM, MacLeod SL, Bamshad MJ, Shaw GM, Finnell RH, Shete SS, Witte JS, Erickson SW, Murphy LD, Hobbs C. PMID: 26033863.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    68. Detecting gene-environment interactions in human birth defects: Study designs and statistical methods. Birth Defects Res A Clin Mol Teratol. 2015 Aug; 103(8):692-702. Tai CG, Graff RE, Liu J, Passarelli MN, Mefford JA, Shaw GM, Hoffmann TJ, Witte JS. PMID: 26010994.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    69. Replication and heritability of prostate cancer risk variants: impact of population-specific factors. Cancer Epidemiol Biomarkers Prev. 2015 Jun; 24(6):938-43. Virlogeux V, Graff RE, Hoffmann TJ, Witte JS. PMID: 25809866.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    70. Associations of prostate cancer risk variants with disease aggressiveness: results of the NCI-SPORE Genetics Working Group analysis of 18,343 cases. Hum Genet. 2015 Apr; 134(4):439-50. Helfand BT, Roehl KA, Cooper PR, McGuire BB, Fitzgerald LM, Cancel-Tassin G, Cornu JN, Bauer S, Van Blarigan EL, Chen X, Duggan D, Ostrander EA, Gwo-Shu M, Zhang ZF, Chang SC, Jeong S, Fontham ET, Smith G, Mohler JL, Berndt SI, McDonnell SK, Kittles R, Rybicki BA, Freedman M, Kantoff PW, Pomerantz M, Breyer JP, Smith JR, Rebbeck TR, Mercola D, Isaacs WB, Wiklund F, Cussenot O, Thibodeau SN, Schaid DJ, Cannon-Albright L, Cooney KA, Chanock SJ, Stanford JL, Chan JM, Witte J, Xu J, Bensen JT, Taylor JA, Catalona WJ. PMID: 25715684.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    71. Imputation of the rare HOXB13 G84E mutation and cancer risk in a large population-based cohort. PLoS Genet. 2015 Jan; 11(1):e1004930. Hoffmann TJ, Sakoda LC, Shen L, Jorgenson E, Habel LA, Liu J, Kvale MN, Asgari MM, Banda Y, Corley D, Kushi LH, Quesenberry CP, Schaefer C, Van Den Eeden SK, Risch N, Witte JS. PMID: 25629170.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    72. Population genetic simulations of complex phenotypes with implications for rare variant association tests. Genet Epidemiol. 2015 Jan; 39(1):35-44. Uricchio LH, Torres R, Witte JS, Hernandez RD. PMID: 25417809.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    73. Genetic polymorphisms in ESR1 and ESR2 genes, and risk of hypospadias in a multiethnic study population. J Urol. 2015 May; 193(5):1625-31. Choudhry S, Baskin LS, Lammer EJ, Witte JS, Dasgupta S, Ma C, Surampalli A, Shen J, Shaw GM, Carmichael SL. PMID: 25463985.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    74. Leveraging population admixture to characterize the heritability of complex traits. Nat Genet. 2014 Dec; 46(12):1356-62. Zaitlen N, Pasaniuc B, Sankararaman S, Bhatia G, Zhang J, Gusev A, Young T, Tandon A, Pollack S, Vilhjálmsson BJ, Assimes TL, Berndt SI, Blot WJ, Chanock S, Franceschini N, Goodman PG, He J, Hennis AJ, Hsing A, Ingles SA, Isaacs W, Kittles RA, Klein EA, Lange LA, Nemesure B, Patterson N, Reich D, Rybicki BA, Stanford JL, Stevens VL, Strom SS, Whitsel EA, Witte JS, Xu J, Haiman C, Wilson JG, Kooperberg C, Stram D, Reiner AP, Tang H, Price AL. PMID: 25383972.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    75. Genetic simulation tools for post-genome wide association studies of complex diseases. Genet Epidemiol. 2015 Jan; 39(1):11-19. Chen HS, Hutter CM, Mechanic LE, Amos CI, Bafna V, Hauser ER, Hernandez RD, Li C, Liberles DA, McAllister K, Moore JH, Paltoo DN, Papanicolaou GJ, Peng B, Ritchie MD, Rosenfeld G, Witte JS, Gillanders EM, Feuer EJ. PMID: 25371374.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    76. Polymorphisms of an innate immune gene, toll-like receptor 4, and aggressive prostate cancer risk: a systematic review and meta-analysis. PLoS One. 2014; 9(10):e110569. Weng PH, Huang YL, Page JH, Chen JH, Xu J, Koutros S, Berndt S, Chanock S, Yeager M, Witte JS, Eeles RA, Easton DF, Neal DE, Donovan J, Hamdy FC, Muir KR, Giles G, Severi G, Smith JR, Balistreri CR, Shui IM, Chen YC. PMID: 25360682.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    77. Selenoprotein and antioxidant genes and the risk of high-grade prostate cancer and prostate cancer recurrence. Prostate. 2015 Jan; 75(1):60-9. Gerstenberger JP, Bauer SR, Van Blarigan EL, Sosa E, Song X, Witte JS, Carroll PR, Chan JM. PMID: 25284284.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    78. Genome-wide scan of 29,141 African Americans finds no evidence of directional selection since admixture. Am J Hum Genet. 2014 Oct 02; 95(4):437-44. Bhatia G, Tandon A, Patterson N, Aldrich MC, Ambrosone CB, Amos C, Bandera EV, Berndt SI, Bernstein L, Blot WJ, Bock CH, Caporaso N, Casey G, Deming SL, Diver WR, Gapstur SM, Gillanders EM, Harris CC, Henderson BE, Ingles SA, Isaacs W, De Jager PL, John EM, Kittles RA, Larkin E, McNeill LH, Millikan RC, Murphy A, Neslund-Dudas C, Nyante S, Press MF, Rodriguez-Gil JL, Rybicki BA, Schwartz AG, Signorello LB, Spitz M, Strom SS, Tucker MA, Wiencke JK, Witte JS, Wu X, Yamamura Y, Zanetti KA, Zheng W, Ziegler RG, Chanock SJ, Haiman CA, Reich D, Price AL. PMID: 25242497.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    79. The contribution of genetic variants to disease depends on the ruler. Nat Rev Genet. 2014 11; 15(11):765-76. Witte JS, Visscher PM, Wray NR. PMID: 25223781.
      View in: PubMed   Mentions: 46     Fields:    Translation:Humans
    80. A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer. Nat Genet. 2014 Oct; 46(10):1103-9. Al Olama AA, Kote-Jarai Z, Berndt SI, Conti DV, Schumacher F, Han Y, Benlloch S, Hazelett DJ, Wang Z, Saunders E, Leongamornlert D, Lindstrom S, Jugurnauth-Little S, Dadaev T, Tymrakiewicz M, Stram DO, Rand K, Wan P, Stram A, Sheng X, Pooler LC, Park K, Xia L, Tyrer J, Kolonel LN, Le Marchand L, Hoover RN, Machiela MJ, Yeager M, Burdette L, Chung CC, Hutchinson A, Yu K, Goh C, Ahmed M, Govindasami K, Guy M, Tammela TL, Auvinen A, Wahlfors T, Schleutker J, Visakorpi T, Leinonen KA, Xu J, Aly M, Donovan J, Travis RC, Key TJ, Siddiq A, Canzian F, Khaw KT, Takahashi A, Kubo M, Pharoah P, Pashayan N, Weischer M, Nordestgaard BG, Nielsen SF, Klarskov P, Røder MA, Iversen P, Thibodeau SN, McDonnell SK, Schaid DJ, Stanford JL, Kolb S, Holt S, Knudsen B, Coll AH, Gapstur SM, Diver WR, Stevens VL, Maier C, Luedeke M, Herkommer K, Rinckleb AE, Strom SS, Pettaway C, Yeboah ED, Tettey Y, Biritwum RB, Adjei AA, Tay E, Truelove A, Niwa S, Chokkalingam AP, Cannon-Albright L, Cybulski C, Wokolorczyk D, Kluzniak W, Park J, Sellers T, Lin HY, Isaacs WB, Partin AW, Brenner H, Dieffenbach AK, Stegmaier C, Chen C, Giovannucci EL, Ma J, Stampfer M, Penney KL, Mucci L, John EM, Ingles SA, Kittles RA, Murphy AB, Pandha H, Michael A, Kierzek AM, Blot W, Signorello LB, Zheng W, Albanes D, Virtamo J, Weinstein S, Nemesure B, Carpten J, Leske C, Wu SY, Hennis A, Kibel AS, Rybicki BA, Neslund-Dudas C, Hsing AW, Chu L, Goodman PJ, Klein EA, Zheng SL, Batra J, Clements J, Spurdle A, Teixeira MR, Paulo P, Maia S, Slavov C, Kaneva R, Mitev V, Witte JS, Casey G, Gillanders EM, Seminara D, Riboli E, Hamdy FC, Coetzee GA, Li Q, Freedman ML, Hunter DJ, Muir K, Gronberg H, Neal DE, Southey M, Giles GG, Severi G, Cook MB, Nakagawa H, Wiklund F, Kraft P, Chanock SJ, Henderson BE, Easton DF, Eeles RA, Haiman CA. PMID: 25217961.
      View in: PubMed   Mentions: 158     Fields:    Translation:Humans
    81. Radiogenomics: radiobiology enters the era of big data and team science. Int J Radiat Oncol Biol Phys. 2014 Jul 15; 89(4):709-13. Rosenstein BS, West CM, Bentzen SM, Alsner J, Andreassen CN, Azria D, Barnett GC, Baumann M, Burnet N, Chang-Claude J, Chuang EY, Coles CE, Dekker A, De Ruyck K, De Ruysscher D, Drumea K, Dunning AM, Easton D, Eeles R, Fachal L, Gutiérrez-Enríquez S, Haustermans K, Henríquez-Hernández LA, Imai T, Jones GD, Kerns SL, Liao Z, Onel K, Ostrer H, Parliament M, Pharoah PD, Rebbeck TR, Talbot CJ, Thierens H, Vega A, Witte JS, Wong P, Zenhausern F. PMID: 24969789.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansPHPublic Health
    82. Generalizability of established prostate cancer risk variants in men of African ancestry. Int J Cancer. 2015 Mar 01; 136(5):1210-7. Han Y, Signorello LB, Strom SS, Kittles RA, Rybicki BA, Stanford JL, Goodman PJ, Berndt SI, Carpten J, Casey G, Chu L, Conti DV, Rand KA, Diver WR, Hennis AJ, John EM, Kibel AS, Klein EA, Kolb S, Le Marchand L, Leske MC, Murphy AB, Neslund-Dudas C, Park JY, Pettaway C, Rebbeck TR, Gapstur SM, Zheng SL, Wu SY, Witte JS, Xu J, Isaacs W, Ingles SA, Hsing A, Easton DF, Eeles RA, Schumacher FR, Chanock S, Nemesure B, Blot WJ, Stram DO, Henderson BE, Haiman CA. PMID: 25044450.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    83. Copy number variation in bronchopulmonary dysplasia. . 2014 Oct; 164A(10):2672-5. Hoffmann TJ, Shaw GM, Stevenson DK, Wang H, Quaintance CC, Oehlert J, Jelliffe-Pawlowski LL, Gould JB, Witte JS, O'Brodovich HM. PMID: 24975634.
      View in: PubMed   Mentions:
    84. Performance of the Genomic Evaluators of Metastatic Prostate Cancer (GEMCaP) tumor biomarker for identifying recurrent disease in African American patients. Cancer Epidemiol Biomarkers Prev. 2014 Aug; 23(8):1677-82. Levin AM, Lindquist KJ, Avila A, Witte JS, Paris PL, Rybicki BA. PMID: 24891551.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    85. Genetic variants in transcription factors are associated with the pharmacokinetics and pharmacodynamics of metformin. Clin Pharmacol Ther. 2014 Sep; 96(3):370-9. Goswami S, Yee SW, Stocker S, Mosley JD, Kubo M, Castro R, Mefford JA, Wen C, Liang X, Witte J, Brett C, Maeda S, Simpson MD, Hedderson MM, Davis RL, Roden DM, Giacomini KM, Savic RM. PMID: 24853734.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    86. Plasma antioxidants, genetic variation in SOD2, CAT, GPX1, GPX4, and prostate cancer survival. Cancer Epidemiol Biomarkers Prev. 2014 Jun; 23(6):1037-46. Van Blarigan EL, Ma J, Kenfield SA, Stampfer MJ, Sesso HD, Giovannucci EL, Witte JS, Erdman JW, Chan JM, Penney KL. PMID: 24711484.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    87. Genetic epidemiology and nonsyndromic structural birth defects: from candidate genes to epigenetics. JAMA Pediatr. 2014 Apr; 168(4):371-7. Hobbs CA, Chowdhury S, Cleves MA, Erickson S, MacLeod SL, Shaw GM, Shete S, Witte JS, Tycko B. PMID: 24515445.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    88. Maternal smoking, xenobiotic metabolizing enzyme gene variants, and gastroschisis risk. . 2014 Jun; 164A(6):1454-63. Jenkins MM, Reefhuis J, Gallagher ML, Mulle JG, Hoffmann TJ, Koontz DA, Sturchio C, Rasmussen SA, Witte JS, Richter P, Honein MA. PMID: 24668907.
      View in: PubMed   Mentions:
    89. Polygenic inheritance of paclitaxel-induced sensory peripheral neuropathy driven by axon outgrowth gene sets in CALGB 40101 (Alliance). Pharmacogenomics J. 2014 Aug; 14(4):336-42. Chhibber A, Mefford J, Stahl EA, Pendergrass SA, Baldwin RM, Owzar K, Li M, Winer EP, Hudis CA, Zembutsu H, Kubo M, Nakamura Y, McLeod HL, Ratain MJ, Shulman LN, Ritchie MD, Plenge RM, Witte JS, Kroetz DL. PMID: 24513692.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCellsCTClinical Trials
    90. Encapsulation status of papillary thyroid microcarcinomas is associated with the risk of lymph node metastases and tumor multifocality. Horm Metab Res. 2014 Feb; 46(2):138-44. Cupisti K, Lehwald N, Anlauf M, Riemer J, Werner TA, Krieg A, Witte J, Chanab A, Baldus SE, Krausch M, Raffel A, Herdter C, Schott M, Knoefel WT. PMID: 24356791.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    91. Mechanistic phenotypes: an aggregative phenotyping strategy to identify disease mechanisms using GWAS data. PLoS One. 2013; 8(12):e81503. Mosley JD, Van Driest SL, Larkin EK, Weeke PE, Witte JS, Wells QS, Karnes JH, Guo Y, Bastarache L, Olson LM, McCarty CA, Pacheco JA, Jarvik GP, Carrell DS, Larson EB, Crosslin DR, Kullo IJ, Tromp G, Kuivaniemi H, Carey DJ, Ritchie MD, Denny JC, Roden DM. PMID: 24349080.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    92. Hypospadias and variants in genes related to sex hormone biosynthesis and metabolism. Andrology. 2014 Jan; 2(1):130-7. Carmichael SL, Witte JS, Ma C, Lammer EJ, Shaw GM. PMID: 24281767.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    93. Antioxidant and vitamin E transport genes and risk of high-grade prostate cancer and prostate cancer recurrence. Prostate. 2013 Dec; 73(16):1786-95. Bauer SR, Richman EL, Sosa E, Weinberg V, Song X, Witte JS, Carroll PR, Chan JM. PMID: 24038157.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    94. Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet. 2013 Sep; 45(9):984-94. Lee SH, Ripke S, Neale BM, Faraone SV, Purcell SM, Perlis RH, Mowry BJ, Thapar A, Goddard ME, Witte JS, Absher D, Agartz I, Akil H, Amin F, Andreassen OA, Anjorin A, Anney R, Anttila V, Arking DE, Asherson P, Azevedo MH, Backlund L, Badner JA, Bailey AJ, Banaschewski T, Barchas JD, Barnes MR, Barrett TB, Bass N, Battaglia A, Bauer M, Bayés M, Bellivier F, Bergen SE, Berrettini W, Betancur C, Bettecken T, Biederman J, Binder EB, Black DW, Blackwood DH, Bloss CS, Boehnke M, Boomsma DI, Breen G, Breuer R, Bruggeman R, Cormican P, Buccola NG, Buitelaar JK, Bunney WE, Buxbaum JD, Byerley WF, Byrne EM, Caesar S, Cahn W, Cantor RM, Casas M, Chakravarti A, Chambert K, Choudhury K, Cichon S, Cloninger CR, Collier DA, Cook EH, Coon H, Cormand B, Corvin A, Coryell WH, Craig DW, Craig IW, Crosbie J, Cuccaro ML, Curtis D, Czamara D, Datta S, Dawson G, Day R, De Geus EJ, Degenhardt F, Djurovic S, Donohoe GJ, Doyle AE, Duan J, Dudbridge F, Duketis E, Ebstein RP, Edenberg HJ, Elia J, Ennis S, Etain B, Fanous A, Farmer AE, Ferrier IN, Flickinger M, Fombonne E, Foroud T, Frank J, Franke B, Fraser C, Freedman R, Freimer NB, Freitag CM, Friedl M, Frisén L, Gallagher L, Gejman PV, Georgieva L, Gershon ES, Geschwind DH, Giegling I, Gill M, Gordon SD, Gordon-Smith K, Green EK, Greenwood TA, Grice DE, Gross M, Grozeva D, Guan W, Gurling H, De Haan L, Haines JL, Hakonarson H, Hallmayer J, Hamilton SP, Hamshere ML, Hansen TF, Hartmann AM, Hautzinger M, Heath AC, Henders AK, Herms S, Hickie IB, Hipolito M, Hoefels S, Holmans PA, Holsboer F, Hoogendijk WJ, Hottenga JJ, Hultman CM, Hus V, Ingason A, Ising M, Jamain S, Jones EG, Jones I, Jones L, Tzeng JY, Kähler AK, Kahn RS, Kandaswamy R, Keller MC, Kennedy JL, Kenny E, Kent L, Kim Y, Kirov GK, Klauck SM, Klei L, Knowles JA, Kohli MA, Koller DL, Konte B, Korszun A, Krabbendam L, Krasucki R, Kuntsi J, Kwan P, Landén M, Långström N, Lathrop M, Lawrence J, Lawson WB, Leboyer M, Ledbetter DH, Lee PH, Lencz T, Lesch KP, Levinson DF, Lewis CM, Li J, Lichtenstein P, Lieberman JA, Lin DY, Linszen DH, Liu C, Lohoff FW, Loo SK, Lord C, Lowe JK, Lucae S, MacIntyre DJ, Madden PA, Maestrini E, Magnusson PK, Mahon PB, Maier W, Malhotra AK, Mane SM, Martin CL, Martin NG, Mattheisen M, Matthews K, Mattingsdal M, McCarroll SA, McGhee KA, McGough JJ, McGrath PJ, McGuffin P, McInnis MG, McIntosh A, McKinney R, McLean AW, McMahon FJ, McMahon WM, McQuillin A, Medeiros H, Medland SE, Meier S, Melle I, Meng F, Meyer J, Middeldorp CM, Middleton L, Milanova V, Miranda A, Monaco AP, Montgomery GW, Moran JL, Moreno-De-Luca D, Morken G, Morris DW, Morrow EM, Moskvina V, Muglia P, Mühleisen TW, Muir WJ, Müller-Myhsok B, Murtha M, Myers RM, Myin-Germeys I, Neale MC, Nelson SF, Nievergelt CM, Nikolov I, Nimgaonkar V, Nolen WA, Nöthen MM, Nurnberger JI, Nwulia EA, Nyholt DR, O'Dushlaine C, Oades RD, Olincy A, Oliveira G, Olsen L, Ophoff RA, Osby U, Owen MJ, Palotie A, Parr JR, Paterson AD, Pato CN, Pato MT, Penninx BW, Pergadia ML, Pericak-Vance MA, Pickard BS, Pimm J, Piven J, Posthuma D, Potash JB, Poustka F, Propping P, Puri V, Quested DJ, Quinn EM, Ramos-Quiroga JA, Rasmussen HB, Raychaudhuri S, Rehnström K, Reif A, Ribasés M, Rice JP, Rietschel M, Roeder K, Roeyers H, Rossin L, Rothenberger A, Rouleau G, Ruderfer D, Rujescu D, Sanders AR, Sanders SJ, Santangelo SL, Sergeant JA, Schachar R, Schalling M, Schatzberg AF, Scheftner WA, Schellenberg GD, Scherer SW, Schork NJ, Schulze TG, Schumacher J, Schwarz M, Scolnick E, Scott LJ, Shi J, Shilling PD, Shyn SI, Silverman JM, Slager SL, Smalley SL, Smit JH, Smith EN, Sonuga-Barke EJ, St Clair D, State M, Steffens M, Steinhausen HC, Strauss JS, Strohmaier J, Stroup TS, Sutcliffe JS, Szatmari P, Szelinger S, Thirumalai S, Thompson RC, Todorov AA, Tozzi F, Treutlein J, Uhr M, van den Oord EJ, Van Grootheest G, Van Os J, Vicente AM, Vieland VJ, Vincent JB, Visscher PM, Walsh CA, Wassink TH, Watson SJ, Weissman MM, Werge T, Wienker TF, Wijsman EM, Willemsen G, Williams N, et al. PMID: 23933821.
      View in: PubMed   Mentions: 674     Fields:    Translation:Humans
    95. A genome-wide association study (GWAS) for bronchopulmonary dysplasia. Pediatrics. 2013 Aug; 132(2):290-7. Wang H, St Julien KR, Stevenson DK, Hoffmann TJ, Witte JS, Lazzeroni LC, Krasnow MA, Quaintance CC, Oehlert JW, Jelliffe-Pawlowski LL, Gould JB, Shaw GM, O'Brodovich HM. PMID: 23897914.
      View in: PubMed   Mentions: 34     Fields:    Translation:Humans
    96. Association of CYP2C9*2 with bosentan-induced liver injury. Clin Pharmacol Ther. 2013 Dec; 94(6):678-86. Markova SM, De Marco T, Bendjilali N, Kobashigawa EA, Mefford J, Sodhi J, Le H, Zhang C, Halladay J, Rettie AE, Khojasteh C, McGlothlin D, Wu AH, Hsueh WC, Witte JS, Schwartz JB, Kroetz DL. PMID: 23863877.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    97. Hypospadias and genes related to genital tubercle and early urethral development. J Urol. 2013 Nov; 190(5):1884-92. Carmichael SL, Ma C, Choudhry S, Lammer EJ, Witte JS, Shaw GM. PMID: 23727413.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    98. Impact of polymorphisms in drug pathway genes on disease-free survival in adults with acute myeloid leukemia. J Hum Genet. 2013 Jun; 58(6):353-61. Yee SW, Mefford JA, Singh N, Percival ME, Stecula A, Yang K, Witte JS, Takahashi A, Kubo M, Matsuda K, Giacomini KM, Andreadis C. PMID: 23677058.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    99. Influence of hyperoxia and physical exercise on *OH-radical stress in humans as measured by dihydroxylated benzoates (DHB) in urine. Undersea Hyperb Med. 2013 May-Jun; 40(3):231-8. Kähler W, Koch I, Wohlrab C, Kowalski J, Witte J, Koch A. PMID: 23789558.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    100. A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry. Nat Genet. 2013 Jun; 45(6):690-6. Monda KL, Chen GK, Taylor KC, Palmer C, Edwards TL, Lange LA, Ng MC, Adeyemo AA, Allison MA, Bielak LF, Chen G, Graff M, Irvin MR, Rhie SK, Li G, Liu Y, Liu Y, Lu Y, Nalls MA, Sun YV, Wojczynski MK, Yanek LR, Aldrich MC, Ademola A, Amos CI, Bandera EV, Bock CH, Britton A, Broeckel U, Cai Q, Caporaso NE, Carlson CS, Carpten J, Casey G, Chen WM, Chen F, Chen YD, Chiang CW, Coetzee GA, Demerath E, Deming-Halverson SL, Driver RW, Dubbert P, Feitosa MF, Feng Y, Freedman BI, Gillanders EM, Gottesman O, Guo X, Haritunians T, Harris T, Harris CC, Hennis AJ, Hernandez DG, McNeill LH, Howard TD, Howard BV, Howard VJ, Johnson KC, Kang SJ, Keating BJ, Kolb S, Kuller LH, Kutlar A, Langefeld CD, Lettre G, Lohman K, Lotay V, Lyon H, Manson JE, Maixner W, Meng YA, Monroe KR, Morhason-Bello I, Murphy AB, Mychaleckyj JC, Nadukuru R, Nathanson KL, Nayak U, N'diaye A, Nemesure B, Wu SY, Leske MC, Neslund-Dudas C, Neuhouser M, Nyante S, Ochs-Balcom H, Ogunniyi A, Ogundiran TO, Ojengbede O, Olopade OI, Palmer JR, Ruiz-Narvaez EA, Palmer ND, Press MF, Rampersaud E, Rasmussen-Torvik LJ, Rodriguez-Gil JL, Salako B, Schadt EE, Schwartz AG, Shriner DA, Siscovick D, Smith SB, Wassertheil-Smoller S, Speliotes EK, Spitz MR, Sucheston L, Taylor H, Tayo BO, Tucker MA, Van Den Berg DJ, Edwards DR, Wang Z, Wiencke JK, Winkler TW, Witte JS, Wrensch M, Wu X, Yang JJ, Levin AM, Young TR, Zakai NA, Cushman M, Zanetti KA, Zhao JH, Zhao W, Zheng Y, Zhou J, Ziegler RG, Zmuda JM, Fernandes JK, Gilkeson GS, Kamen DL, Hunt KJ, Spruill IJ, Ambrosone CB, Ambs S, Arnett DK, Atwood L, Becker DM, Berndt SI, Bernstein L, Blot WJ, Borecki IB, Bottinger EP, Bowden DW, Burke G, Chanock SJ, Cooper RS, Ding J, Duggan D, Evans MK, Fox C, Garvey WT, Bradfield JP, Hakonarson H, Grant SF, Hsing A, Chu L, Hu JJ, Huo D, Ingles SA, John EM, Jordan JM, Kabagambe EK, Kardia SL, Kittles RA, Goodman PJ, Klein EA, Kolonel LN, Le Marchand L, Liu S, McKnight B, Millikan RC, Mosley TH, Padhukasahasram B, Williams LK, Patel SR, Peters U, Pettaway CA, Peyser PA, Psaty BM, Redline S, Rotimi CN, Rybicki BA, Sale MM, Schreiner PJ, Signorello LB, Singleton AB, Stanford JL, Strom SS, Thun MJ, Vitolins M, Zheng W, Moore JH, Williams SM, Ketkar S, Zhu X, Zonderman AB, Kooperberg C, Papanicolaou GJ, Henderson BE, Reiner AP, Hirschhorn JN, Loos RJ, North KE, Haiman CA. PMID: 23583978.
      View in: PubMed   Mentions: 109     Fields:    Translation:Humans
    101. Does accounting for gene-environment interactions help uncover association between rare variants and complex diseases? Hum Hered. 2012; 74(3-4):205-14. Kazma R, Cardin NJ, Witte JS. PMID: 23594498.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    102. Turning of COGS moves forward findings for hormonally mediated cancers. Nat Genet. 2013 Apr; 45(4):345-8. Sakoda LC, Jorgenson E, Witte JS. PMID: 23535722.
      View in: PubMed   Mentions: 34     Fields:    Translation:Humans
    103. The impact of improved microarray coverage and larger sample sizes on future genome-wide association studies. Genet Epidemiol. 2013 May; 37(4):383-92. Lindquist KJ, Jorgenson E, Hoffmann TJ, Witte JS. PMID: 23529720.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    104. Global patterns of prostate cancer incidence, aggressiveness, and mortality in men of african descent. Prostate Cancer. 2013; 2013:560857. Rebbeck TR, Devesa SS, Chang BL, Bunker CH, Cheng I, Cooney K, Eeles R, Fernandez P, Giri VN, Gueye SM, Haiman CA, Henderson BE, Heyns CF, Hu JJ, Ingles SA, Isaacs W, Jalloh M, John EM, Kibel AS, Kidd LR, Layne P, Leach RJ, Neslund-Dudas C, Okobia MN, Ostrander EA, Park JY, Patrick AL, Phelan CM, Ragin C, Roberts RA, Rybicki BA, Stanford JL, Strom S, Thompson IM, Witte J, Xu J, Yeboah E, Hsing AW, Zeigler-Johnson CM. PMID: 23476788.
      View in: PubMed   Mentions:
    105. HOXB13 mutation and prostate cancer: studies of siblings and aggressive disease. Cancer Epidemiol Biomarkers Prev. 2013 Apr; 22(4):675-80. Witte JS, Mefford J, Plummer SJ, Liu J, Cheng I, Klein EA, Rybicki BA, Casey G. PMID: 23396964.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    106. Hierarchical modeling identifies novel lung cancer susceptibility variants in inflammation pathways among 10,140 cases and 11,012 controls. Hum Genet. 2013 05; 132(5):579-89. Brenner DR, Brennan P, Boffetta P, Amos CI, Spitz MR, Chen C, Goodman G, Heinrich J, Bickeböller H, Rosenberger A, Risch A, Muley T, McLaughlin JR, Benhamou S, Bouchardy C, Lewinger JP, Witte JS, Chen G, Bull S, Hung RJ. PMID: 23370545.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    107. Association of the innate immunity and inflammation pathway with advanced prostate cancer risk. PLoS One. 2012; 7(12):e51680. Kazma R, Mefford JA, Cheng I, Plummer SJ, Levin AM, Rybicki BA, Casey G, Witte JS. PMID: 23272139.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    108. Diacylglycerol kinase K variants impact hypospadias in a California study population. J Urol. 2013 Jan; 189(1):305-11. Carmichael SL, Mohammed N, Ma C, Iovannisci D, Choudhry S, Baskin LS, Witte JS, Shaw GM, Lammer EJ. PMID: 23177175.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    109. The Covariate's Dilemma. PLoS Genet. 2012; 8(11):e1003096. Mefford J, Witte JS. PMID: 23162385.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    110. Reclassify controls at your own risk. Epidemiology. 2012 Nov; 23(6):910-1. Witte JS, Visscher PM. PMID: 23038114.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    111. A genome-wide association study identifies novel loci for paclitaxel-induced sensory peripheral neuropathy in CALGB 40101. Clin Cancer Res. 2012 Sep 15; 18(18):5099-109. Baldwin RM, Owzar K, Zembutsu H, Chhibber A, Kubo M, Jiang C, Watson D, Eclov RJ, Mefford J, McLeod HL, Friedman PN, Hudis CA, Winer EP, Jorgenson EM, Witte JS, Shulman LN, Nakamura Y, Ratain MJ, Kroetz DL. PMID: 22843789.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCells
    112. The future of clinical trials: A panel discussion. Stat Med. 2012 Nov 10; 31(25):3068-72. D'Agostino R, DeMets D, Friedewald W, Goodman S, Witte J, Geller NL. PMID: 22806631.
      View in: PubMed   Mentions:    Fields:    
    113. Joint association testing of common and rare genetic variants using hierarchical modeling. Genet Epidemiol. 2012 Sep; 36(6):642-51. Cardin NJ, Mefford JA, Witte JS. PMID: 22807252.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    114. Rare genetic variants and treatment response: sample size and analysis issues. Stat Med. 2012 Nov 10; 31(25):3041-50. Witte JS. PMID: 22736504.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    115. Genome-wide meta-analyses of smoking behaviors in African Americans. Transl Psychiatry. 2012 May 22; 2:e119. David SP, Hamidovic A, Chen GK, Bergen AW, Wessel J, Kasberger JL, Brown WM, Petruzella S, Thacker EL, Kim Y, Nalls MA, Tranah GJ, Sung YJ, Ambrosone CB, Arnett D, Bandera EV, Becker DM, Becker L, Berndt SI, Bernstein L, Blot WJ, Broeckel U, Buxbaum SG, Caporaso N, Casey G, Chanock SJ, Deming SL, Diver WR, Eaton CB, Evans DS, Evans MK, Fornage M, Franceschini N, Harris TB, Henderson BE, Hernandez DG, Hitsman B, Hu JJ, Hunt SC, Ingles SA, John EM, Kittles R, Kolb S, Kolonel LN, Le Marchand L, Liu Y, Lohman KK, McKnight B, Millikan RC, Murphy A, Neslund-Dudas C, Nyante S, Press M, Psaty BM, Rao DC, Redline S, Rodriguez-Gil JL, Rybicki BA, Signorello LB, Singleton AB, Smoller J, Snively B, Spring B, Stanford JL, Strom SS, Swan GE, Taylor KD, Thun MJ, Wilson AF, Witte JS, Yamamura Y, Yanek LR, Yu K, Zheng W, Ziegler RG, Zonderman AB, Jorgenson E, Haiman CA, Furberg H. PMID: 22832964.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansCells
    116. The association between a Darc gene polymorphism and clinical outcomes in African American patients with acute lung injury. Chest. 2012 May; 141(5):1160-1169. Kangelaris KN, Sapru A, Calfee CS, Liu KD, Pawlikowska L, Witte JS, Vittinghoff E, Zhuo H, Auerbach AD, Ziv E, Matthay MA. PMID: 22207676.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    117. Next generation analytic tools for large scale genetic epidemiology studies of complex diseases. Genet Epidemiol. 2012 Jan; 36(1):22-35. Mechanic LE, Chen HS, Amos CI, Chatterjee N, Cox NJ, Divi RL, Fan R, Harris EL, Jacobs K, Kraft P, Leal SM, McAllister K, Moore JH, Paltoo DN, Province MA, Ramos EM, Ritchie MD, Roeder K, Schaid DJ, Stephens M, Thomas DC, Weinberg CR, Witte JS, Zhang S, Zöllner S, Feuer EJ, Gillanders EM. PMID: 22147673.
      View in: PubMed   Mentions: 34     Fields:    Translation:Humans
    118. A genetic signature of spina bifida risk from pathway-informed comprehensive gene-variant analysis. PLoS One. 2011; 6(11):e28408. Marini NJ, Hoffmann TJ, Lammer EJ, Hardin J, Lazaruk K, Stein JB, Gilbert DA, Wright C, Lipzen A, Pennacchio LA, Carmichael SL, Witte JS, Shaw GM, Rine J. PMID: 22140583.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    119. Use of principal components to aggregate rare variants in case-control and family-based association studies in the presence of multiple covariates. BMC Proc. 2011 Nov 29; 5 Suppl 9:S29. Kazma R, Hoffmann TJ, Witte JS. PMID: 22373382.
      View in: PubMed   Mentions:
    120. Impact of meat consumption, preparation, and mutagens on aggressive prostate cancer. PLoS One. 2011; 6(11):e27711. Punnen S, Hardin J, Cheng I, Klein EA, Witte JS. PMID: 22132129.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    121. Variations in the heme oxygenase-1 microsatellite polymorphism are associated with plasma CD14 and viral load in HIV-infected African-Americans. Genes Immun. 2012 Apr; 13(3):258-67. Seu L, Burt TD, Witte JS, Martin JN, Deeks SG, McCune JM. PMID: 22048453.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    122. Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry. PLoS Genet. 2011 Oct; 7(10):e1002298. N'Diaye A, Chen GK, Palmer CD, Ge B, Tayo B, Mathias RA, Ding J, Nalls MA, Adeyemo A, Adoue V, Ambrosone CB, Atwood L, Bandera EV, Becker LC, Berndt SI, Bernstein L, Blot WJ, Boerwinkle E, Britton A, Casey G, Chanock SJ, Demerath E, Deming SL, Diver WR, Fox C, Harris TB, Hernandez DG, Hu JJ, Ingles SA, John EM, Johnson C, Keating B, Kittles RA, Kolonel LN, Kritchevsky SB, Le Marchand L, Lohman K, Liu J, Millikan RC, Murphy A, Musani S, Neslund-Dudas C, North KE, Nyante S, Ogunniyi A, Ostrander EA, Papanicolaou G, Patel S, Pettaway CA, Press MF, Redline S, Rodriguez-Gil JL, Rotimi C, Rybicki BA, Salako B, Schreiner PJ, Signorello LB, Singleton AB, Stanford JL, Stram AH, Stram DO, Strom SS, Suktitipat B, Thun MJ, Witte JS, Yanek LR, Ziegler RG, Zheng W, Zhu X, Zmuda JM, Zonderman AB, Evans MK, Liu Y, Becker DM, Cooper RS, Pastinen T, Henderson BE, Hirschhorn JN, Lettre G, Haiman CA. PMID: 21998595.
      View in: PubMed   Mentions: 49     Fields:    Translation:Humans
    123. Copy number alterations in prostate tumors and disease aggressiveness. Genes Chromosomes Cancer. 2012 Jan; 51(1):66-76. Cheng I, Levin AM, Tai YC, Plummer S, Chen GK, Neslund-Dudas C, Casey G, Rybicki BA, Witte JS. PMID: 21965145.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    124. A common 5'-UTR variant in MATE2-K is associated with poor response to metformin. Clin Pharmacol Ther. 2011 Nov; 90(5):674-84. Choi JH, Yee SW, Ramirez AH, Morrissey KM, Jang GH, Joski PJ, Mefford JA, Hesselson SE, Schlessinger A, Jenkins G, Castro RA, Johns SJ, Stryke D, Sali A, Ferrin TE, Witte JS, Kwok PY, Roden DM, Wilke RA, McCarty CA, Davis RL, Giacomini KM. PMID: 21956618.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    125. Evaluation of polymorphisms in EWSR1 and risk of Ewing sarcoma: a report from the Childhood Cancer Survivor Study. Pediatr Blood Cancer. 2012 Jul 15; 59(1):52-6. DuBois SG, Goldsby R, Segal M, Woo J, Copren K, Kane JP, Pullinger CR, Matthay KK, Witte J, Lessnick SL, Robison LL, Bhatia S, Strong LC. PMID: 21793187.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCTClinical Trials
    126. The landscape of recombination in African Americans. Nature. 2011 Jul 20; 476(7359):170-5. Hinch AG, Tandon A, Patterson N, Song Y, Rohland N, Palmer CD, Chen GK, Wang K, Buxbaum SG, Akylbekova EL, Aldrich MC, Ambrosone CB, Amos C, Bandera EV, Berndt SI, Bernstein L, Blot WJ, Bock CH, Boerwinkle E, Cai Q, Caporaso N, Casey G, Cupples LA, Deming SL, Diver WR, Divers J, Fornage M, Gillanders EM, Glessner J, Harris CC, Hu JJ, Ingles SA, Isaacs W, John EM, Kao WH, Keating B, Kittles RA, Kolonel LN, Larkin E, Le Marchand L, McNeill LH, Millikan RC, Murphy A, Musani S, Neslund-Dudas C, Nyante S, Papanicolaou GJ, Press MF, Psaty BM, Reiner AP, Rich SS, Rodriguez-Gil JL, Rotter JI, Rybicki BA, Schwartz AG, Signorello LB, Spitz M, Strom SS, Thun MJ, Tucker MA, Wang Z, Wiencke JK, Witte JS, Wrensch M, Wu X, Yamamura Y, Zanetti KA, Zheng W, Ziegler RG, Zhu X, Redline S, Hirschhorn JN, Henderson BE, Taylor HA, Price AL, Hakonarson H, Chanock SJ, Haiman CA, Wilson JG, Reich D, Myers SR. PMID: 21775986.
      View in: PubMed   Mentions: 134     Fields:    Translation:HumansCells
    127. Impact of consumption of vegetable, fruit, grain, and high glycemic index foods on aggressive prostate cancer risk. Nutr Cancer. 2011; 63(6):860-72. Hardin J, Cheng I, Witte JS. PMID: 21774611.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsPHPublic Health
    128. Of models and methods. Cancer Epidemiol Biomarkers Prev. 2011 Jun; 20(6):1059-60. Witte JS. PMID: 21652535.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    129. Characterizing genetic risk at known prostate cancer susceptibility loci in African Americans. PLoS Genet. 2011 May; 7(5):e1001387. Haiman CA, Chen GK, Blot WJ, Strom SS, Berndt SI, Kittles RA, Rybicki BA, Isaacs WB, Ingles SA, Stanford JL, Diver WR, Witte JS, Chanock SJ, Kolb S, Signorello LB, Yamamura Y, Neslund-Dudas C, Thun MJ, Murphy A, Casey G, Sheng X, Wan P, Pooler LC, Monroe KR, Waters KM, Le Marchand L, Kolonel LN, Stram DO, Henderson BE. PMID: 21637779.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansCells
    130. Genome-wide association study of prostate cancer in men of African ancestry identifies a susceptibility locus at 17q21. Nat Genet. 2011 Jun; 43(6):570-3. Haiman CA, Chen GK, Blot WJ, Strom SS, Berndt SI, Kittles RA, Rybicki BA, Isaacs WB, Ingles SA, Stanford JL, Diver WR, Witte JS, Hsing AW, Nemesure B, Rebbeck TR, Cooney KA, Xu J, Kibel AS, Hu JJ, John EM, Gueye SM, Watya S, Signorello LB, Hayes RB, Wang Z, Yeboah E, Tettey Y, Cai Q, Kolb S, Ostrander EA, Zeigler-Johnson C, Yamamura Y, Neslund-Dudas C, Haslag-Minoff J, Wu W, Thomas V, Allen GO, Murphy A, Chang BL, Zheng SL, Leske MC, Wu SY, Ray AM, Hennis AJ, Thun MJ, Carpten J, Casey G, Carter EN, Duarte ER, Xia LY, Sheng X, Wan P, Pooler LC, Cheng I, Monroe KR, Schumacher F, Le Marchand L, Kolonel LN, Chanock SJ, Van Den Berg D, Stram DO, Henderson BE. PMID: 21602798.
      View in: PubMed   Mentions: 105     Fields:    Translation:HumansCells
    131. National Cancer Institute Prostate Cancer Genetics Workshop. Cancer Res. 2011 May 15; 71(10):3442-6. Catalona WJ, Bailey-Wilson JE, Camp NJ, Chanock SJ, Cooney KA, Easton DF, Eeles RA, FitzGerald LM, Freedman ML, Gudmundsson J, Kittles RA, Margulies EH, McGuire BB, Ostrander EA, Rebbeck TR, Stanford JL, Thibodeau SN, Witte JS, Isaacs WB. PMID: 21558387.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    132. Parallel biocomputing. Source Code Biol Med. 2011 Mar 18; 6:4. Kompass KS, Hoffmann TJ, Witte JS. PMID: 21418580.
      View in: PubMed   Mentions:
    133. Polygenic modeling of genome-wide association studies: an application to prostate and breast cancer. OMICS. 2011 Jun; 15(6):393-8. Witte JS, Hoffmann TJ. PMID: 21348634.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    134. Co-regulatory expression quantitative trait loci mapping: method and application to endometrial cancer. BMC Med Genomics. 2011 Jan 12; 4:6. Kompass KS, Witte JS. PMID: 21226949.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    135. Personalized prostate cancer screening: improving PSA tests with genomic information. Sci Transl Med. 2010 Dec 15; 2(62):62ps55. Witte JS. PMID: 21160075.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    136. Validation of genome-wide prostate cancer associations in men of African descent. Cancer Epidemiol Biomarkers Prev. 2011 Jan; 20(1):23-32. Chang BL, Spangler E, Gallagher S, Haiman CA, Henderson B, Isaacs W, Benford ML, Kidd LR, Cooney K, Strom S, Ingles SA, Stern MC, Corral R, Joshi AD, Xu J, Giri VN, Rybicki B, Neslund-Dudas C, Kibel AS, Thompson IM, Leach RJ, Ostrander EA, Stanford JL, Witte J, Casey G, Eeles R, Hsing AW, Chanock S, Hu JJ, John EM, Park J, Stefflova K, Zeigler-Johnson C, Rebbeck TR. PMID: 21071540.
      View in: PubMed   Mentions: 53     Fields:    Translation:Humans
    137. Comprehensive approach to analyzing rare genetic variants. PLoS One. 2010 Nov 03; 5(11):e13584. Hoffmann TJ, Marini NJ, Witte JS. PMID: 21072163.
      View in: PubMed   Mentions: 79     Fields:    Translation:Humans
    138. Fine-mapping of prostate cancer aggressiveness loci on chromosome 7q22-35. Prostate. 2011 May 15; 71(7):682-9. Liu X, Cheng I, Plummer SJ, Suarez BK, Casey G, Catalona WJ, Witte JS. PMID: 20945404.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    139. Non-Steroidal Anti-Inflammatory Drugs, Variation in Inflammatory Genes, and Aggressive Prostate Cancer. Pharmaceuticals (Basel). 2010 Oct 08; 3(10):3127-3142. Reese AC, Hardin J, Cheng I, Casey G, Witte JS. PMID: 24023525.
      View in: PubMed   Mentions:
    140. Segmentation and estimation for SNP microarrays: a Bayesian multiple change-point approach. Biometrics. 2010 Sep; 66(3):675-83. Tai YC, Kvale MN, Witte JS. PMID: 19764955.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    141. Prostate cancer susceptibility variants confer increased risk of disease progression. Cancer Epidemiol Biomarkers Prev. 2010 Sep; 19(9):2124-32. Cheng I, Plummer SJ, Neslund-Dudas C, Klein EA, Casey G, Rybicki BA, Witte JS. PMID: 20651075.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    142. Conference Scene: Lessons learned from the 5th Statistical Analysis Workshop of the Pharmacogenetics Research Network. Pharmacogenomics. 2010 Mar; 11(3):297-303. Atkinson EJ, McDonnell SK, Witte JS, Crawford DC, Fan Y, Fridley B, Li D, Li L, Rodin A, Sadee W, Speed T, Weiss ST, Yang J, Yerges L, Schaid DJ. PMID: 20235785.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    143. Prostatitis, sexually transmitted diseases, and prostate cancer: the California Men's Health Study. PLoS One. 2010 Jan 15; 5(1):e8736. Cheng I, Witte JS, Jacobsen SJ, Haque R, Quinn VP, Quesenberry CP, Caan BJ, Van Den Eeden SK. PMID: 20090948.
      View in: PubMed   Mentions: 39     Fields:    Translation:Humans
    144. Genome-wide association studies and beyond. Annu Rev Public Health. 2010; 31:9-20 4 p following 20. Witte JS. PMID: 20235850.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansPHPublic Health
    145. VALID: visualization of association study results and linkage disequilibrium. Genet Epidemiol. 2009 Nov; 33(7):599-603. Jorgenson E, Kvale M, Witte JS. PMID: 19197947.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    146. Omega-3 fatty acids, genetic variants in COX-2 and prostate cancer. J Nutrigenet Nutrigenomics. 2009; 2(3):149-58. Reese AC, Fradet V, Witte JS. PMID: 19776642.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    147. The Scientific Foundation for personal genomics: recommendations from a National Institutes of Health-Centers for Disease Control and Prevention multidisciplinary workshop. Genet Med. 2009 Aug; 11(8):559-67. Khoury MJ, McBride CM, Schully SD, Ioannidis JP, Feero WG, Janssens AC, Gwinn M, Simons-Morton DG, Bernhardt JM, Cargill M, Chanock SJ, Church GM, Coates RJ, Collins FS, Croyle RT, Davis BR, Downing GJ, Duross A, Friedman S, Gail MH, Ginsburg GS, Green RC, Greene MH, Greenland P, Gulcher JR, Hsu A, Hudson KL, Kardia SL, Kimmel PL, Lauer MS, Miller AM, Offit K, Ransohoff DF, Roberts JS, Rasooly RS, Stefansson K, Terry SF, Teutsch SM, Trepanier A, Wanke KL, Witte JS, Xu J. PMID: 19617843.
      View in: PubMed   Mentions: 82     Fields:    Translation:Humans
    148. Socioeconomic status and prostate cancer incidence and mortality rates among the diverse population of California. Cancer Causes Control. 2009 Oct; 20(8):1431-40. Cheng I, Witte JS, McClure LA, Shema SJ, Cockburn MG, John EM, Clarke CA. PMID: 19526319.
      View in: PubMed   Mentions: 39     Fields:    Translation:Humans
    149. Dietary omega-3 fatty acids, cyclooxygenase-2 genetic variation, and aggressive prostate cancer risk. Clin Cancer Res. 2009 Apr 01; 15(7):2559-66. Fradet V, Cheng I, Casey G, Witte JS. PMID: 19318492.
      View in: PubMed   Mentions: 39     Fields:    Translation:Humans
    150. Carboxypeptidase 4 gene variants and early-onset intermediate-to-high risk prostate cancer. BMC Cancer. 2009 Feb 26; 9:69. Ross PL, Cheng I, Liu X, Cicek MS, Carroll PR, Casey G, Witte JS. PMID: 19245716.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    151. Nutrient pathways and neural tube defects: a semi-Bayesian hierarchical analysis. Epidemiology. 2009 Jan; 20(1):67-73. Carmichael SL, Witte JS, Shaw GM. PMID: 19234400.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansPHPublic Health
    152. Prostate cancer genomics: towards a new understanding. Nat Rev Genet. 2009 Feb; 10(2):77-82. Witte JS. PMID: 19104501.
      View in: PubMed   Mentions: 51     Fields:    Translation:Humans
    153. New classification of chronic GVHD: added clarity from the consensus diagnoses. Bone Marrow Transplant. 2009 Jan; 43(2):149-53. Arora M, Nagaraj S, Witte J, DeFor TE, MacMillan M, Burns LJ, Weisdorf DJ. PMID: 18794869.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    154. The role of genetic variation in Toll-like receptor 4 in prostate cancer susceptibility: a review. Expert Opin Med Diagn. 2008 Feb; 2(2):143-9. Cheng I, Witte JS. PMID: 23485134.
      View in: PubMed   Mentions:    Fields:    
    155. 8q24 and prostate cancer: association with advanced disease and meta-analysis. Eur J Hum Genet. 2008 Apr; 16(4):496-505. Cheng I, Plummer SJ, Jorgenson E, Liu X, Rybicki BA, Casey G, Witte JS. PMID: 18231127.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCells
    156. Genetic Analysis Workshop 15: gene expression analysis and approaches to detecting multiple functional loci. BMC Proc. 2007; 1 Suppl 1:S1. Cordell HJ, de Andrade M, Babron MC, Bartlett CW, Beyene J, Bickeböller H, Culverhouse R, Cupples LA, Daw EW, Dupuis J, Falk CT, Ghosh S, Goddard KA, Goode EL, Hauser ER, Martin LJ, Martinez M, North KE, Saccone NL, Schmidt S, Tapper W, Thomas D, Tritchler D, Vieland VJ, Wijsman EM, Wilcox MA, Witte JS, Yang Q, Ziegler A, Almasy L, Maccluer JW. PMID: 18466438.
      View in: PubMed   Mentions:
    157. An empirical evaluation of the common disease-common variant hypothesis. BMC Proc. 2007; 1 Suppl 1:S5. Chen GK, Jorgenson E, Witte JS. PMID: 18466549.
      View in: PubMed   Mentions:
    158. Genome-wide association studies of cancer. Future Oncol. 2007 Aug; 3(4):419-27. Jorgenson E, Witte JS. PMID: 17661717.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    159. COX2 genetic variation, NSAIDs, and advanced prostate cancer risk. Br J Cancer. 2007 Aug 20; 97(4):557-61. Cheng I, Liu X, Plummer SJ, Krumroy LM, Casey G, Witte JS. PMID: 17609663.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    160. Enriching the analysis of genomewide association studies with hierarchical modeling. Am J Hum Genet. 2007 Aug; 81(2):397-404. Chen GK, Witte JS. PMID: 17668389.
      View in: PubMed   Mentions: 51     Fields:    Translation:Humans
    161. MIC1 and IL1RN genetic variation and advanced prostate cancer risk. Cancer Epidemiol Biomarkers Prev. 2007 Jun; 16(6):1309-11. Cheng I, Krumroy LM, Plummer SJ, Casey G, Witte JS. PMID: 17548705.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    162. Multiple prostate cancer risk variants on 8q24. Nat Genet. 2007 May; 39(5):579-80. Witte JS. PMID: 17460686.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
    163. Dissecting effects of complex mixtures: who's afraid of informative priors? Epidemiology. 2007 Mar; 18(2):186-90. Thomas DC, Witte JS, Greenland S. PMID: 17301703.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    164. Association of testis derived transcript gene variants and prostate cancer risk. J Urol. 2007 Mar; 177(3):894-8. Liu X, Cicek MS, Plummer SJ, Jorgenson E, Casey G, Witte JS. PMID: 17296370.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    165. Toll-like receptor 4 genetic variation and advanced prostate cancer risk. Cancer Epidemiol Biomarkers Prev. 2007 Feb; 16(2):352-5. Cheng I, Plummer SJ, Casey G, Witte JS. PMID: 17301271.
      View in: PubMed   Mentions: 39     Fields:    Translation:Humans
    166. Plasminogen activator inhibitor type-1 (PAI-1) polymorphism 4G/5G is associated with prostate cancer among men with a positive family history. Prostate. 2007 Feb 01; 67(2):172-7. Jorgenson E, Deitcher SR, Cicek M, Liu X, Plummer S, Casey G, Witte JS. PMID: 17044080.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    167. Trans-fatty acid intake and increased risk of advanced prostate cancer: modification by RNASEL R462Q variant. Carcinogenesis. 2007 Jun; 28(6):1232-6. Liu X, Schumacher FR, Plummer SJ, Jorgenson E, Casey G, Witte JS. PMID: 17234723.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    168. Introduction to Genetic Analysis Workshop 15 summaries. Genet Epidemiol. 2007; 31 Suppl 1:S1-6. Witte JS, Schnell AH, Cordell HJ, Spielman RS, Amos CI, Miller MB, Almasy L, MacCluer JW. PMID: 18046756.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    169. Genome-wide association analyses of expression phenotypes. Genet Epidemiol. 2007; 31 Suppl 1:S7-S11. Chen GK, Zheng T, Witte JS, Goode EL, Gao L, Hu P, Suh YJ, Suktitipat B, Szymczak S, Woo JH, Zhang W. PMID: 18046762.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    170. Vitamin D receptor genotypes/haplotypes and prostate cancer risk. Cancer Epidemiol Biomarkers Prev. 2006 Dec; 15(12):2549-52. Cicek MS, Liu X, Schumacher FR, Casey G, Witte JS. PMID: 17164384.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    171. A gene-centric approach to genome-wide association studies. Nat Rev Genet. 2006 Nov; 7(11):885-91. Jorgenson E, Witte JS. PMID: 17047687.
      View in: PubMed   Mentions: 43     Fields:    Translation:Humans
    172. Nonsteroidal antiinflammatory drugs and decreased risk of advanced prostate cancer: modification by lymphotoxin alpha. Am J Epidemiol. 2006 Nov 15; 164(10):984-9. Liu X, Plummer SJ, Nock NL, Casey G, Witte JS. PMID: 16931544.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    173. Novel missense mutations of the Deleted-in-AZoospermia-Like (DAZL) gene in infertile women and men. Reprod Biol Endocrinol. 2006 Aug 02; 4:40. Tung JY, Rosen MP, Nelson LM, Turek PJ, Witte JS, Cramer DW, Cedars MI, Reijo-Pera RA. PMID: 16884537.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    174. Acute lung injury and the coagulation pathway: Potential role of gene polymorphisms in the protein C and fibrinolytic pathways. Intensive Care Med. 2006 Sep; 32(9):1293-303. Sapru A, Wiemels JL, Witte JS, Ware LB, Matthay MA. PMID: 16770611.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    175. Polymorphisms in polycyclic aromatic hydrocarbon metabolism and conjugation genes, interactions with smoking and prostate cancer risk. Cancer Epidemiol Biomarkers Prev. 2006 Apr; 15(4):756-61. Nock NL, Liu X, Cicek MS, Li L, Macarie F, Rybicki BA, Plummer SJ, Maclennan GT, Casey G, Witte JS. PMID: 16614120.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    176. Polymorphisms in estrogen bioactivation, detoxification and oxidative DNA base excision repair genes and prostate cancer risk. Carcinogenesis. 2006 Sep; 27(9):1842-8. Nock NL, Cicek MS, Li L, Liu X, Rybicki BA, Moreira A, Plummer SJ, Casey G, Witte JS. PMID: 16569655.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    177. Coverage and power in genomewide association studies. Am J Hum Genet. 2006 May; 78(5):884-888. Jorgenson E, Witte JS. PMID: 16642443.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    178. Podocalyxin variants and risk of prostate cancer and tumor aggressiveness. Hum Mol Genet. 2006 Mar 01; 15(5):735-41. Casey G, Neville PJ, Liu X, Plummer SJ, Cicek MS, Krumroy LM, Curran AP, McGreevy MR, Catalona WJ, Klein EA, Witte JS. PMID: 16434482.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansCells
    179. Hierarchical modeling in association studies of multiple phenotypes. BMC Genet. 2005 Dec 30; 6 Suppl 1:S104. Liu X, Jorgenson E, Witte JS. PMID: 16451560.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    180. Relationship between body size and prostate cancer in a sibling based case-control study. J Urol. 2005 Dec; 174(6):2169-73. Liu X, Rybicki BA, Casey G, Witte JS. PMID: 16280757.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    181. Variants in Deleted in AZoospermia-Like (DAZL) are correlated with reproductive parameters in men and women. Hum Genet. 2006 Feb; 118(6):730-40. Tung JY, Rosen MP, Nelson LM, Turek PJ, Witte JS, Cramer DW, Cedars MI, Pera RA. PMID: 16328470.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    182. No association between genetic polymorphisms in insulin and insulin receptor substrate-1 and prostate cancer. Cancer Epidemiol Biomarkers Prev. 2005 Oct; 14(10):2462-3. Li L, Cicek MS, Casey G, Witte JS. PMID: 16214935.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    183. Role of androgen metabolism genes CYP1B1, PSA/KLK3, and CYP11alpha in prostate cancer risk and aggressiveness. Cancer Epidemiol Biomarkers Prev. 2005 Sep; 14(9):2173-7. Cicek MS, Liu X, Casey G, Witte JS. PMID: 16172228.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    184. Gene symbol: KCNQ2. Disease: Benign neonatal familial convulsion. Hum Genet. 2005 Jul; 117(2-3):300. Pinto D, de Haan GJ, Carton D, Bader A, Witte J, Peters E, van Erp MG, Vandereyken W, Boezeman EH, Boon P, Halley DJ, Koeleman BP, Lindhout D. PMID: 16156031.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    185. Case-control analyses: Geneopardy! Genet Epidemiol. 2005; 29 Suppl 1:S86-90. Jorgenson E, Liu X, Witte JS. PMID: 16342187.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    186. No association between a tetranucleotide repeat polymorphism of CYP19 and prostate cancer. Cancer Epidemiol Biomarkers Prev. 2004 Dec; 13(12):2280-1. Li L, Cicek MS, Casey G, Witte JS. PMID: 15598794.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    187. Increased power for case-control studies of single nucleotide polymorphisms through incorporation of family history and genetic constraints. Genet Epidemiol. 2004 Nov; 27(3):215-24. Thompson D, Witte JS, Slattery M, Goldgar D. PMID: 15389928.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    188. Relationship between methylenetetrahydrofolate reductase C677T and A1298C genotypes and haplotypes and prostate cancer risk and aggressiveness. Cancer Epidemiol Biomarkers Prev. 2004 Aug; 13(8):1331-6. Cicek MS, Nock NL, Li L, Conti DV, Casey G, Witte JS. PMID: 15298954.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    189. Using hierarchical modeling in genetic association studies with multiple markers: application to a case-control study of bladder cancer. Cancer Epidemiol Biomarkers Prev. 2004 Jun; 13(6):1013-21. Hung RJ, Brennan P, Malaveille C, Porru S, Donato F, Boffetta P, Witte JS. PMID: 15184258.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansPHPublic Health
    190. Association of prostate cancer risk and aggressiveness to androgen pathway genes: SRD5A2, CYP17, and the AR. Prostate. 2004 Apr 01; 59(1):69-76. Cicek MS, Conti DV, Curran A, Neville PJ, Paris PL, Casey G, Witte JS. PMID: 14991867.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    191. Comprehensive evaluation of the association between prostate cancer and genotypes/haplotypes in CYP17A1, CYP3A4, and SRD5A2. Eur J Hum Genet. 2004 Apr; 12(4):321-32. Loukola A, Chadha M, Penn SG, Rank D, Conti DV, Thompson D, Cicek M, Love B, Bivolarevic V, Yang Q, Jiang Y, Hanzel DK, Dains K, Paris PL, Casey G, Witte JS. PMID: 14560315.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    192. Genetic dissection of complex traits with chromosome substitution strains of mice. Science. 2004 Apr 16; 304(5669):445-8. Singer JB, Hill AE, Burrage LC, Olszens KR, Song J, Justice M, O'Brien WE, Conti DV, Witte JS, Lander ES, Nadeau JH. PMID: 15031436.
      View in: PubMed   Mentions: 137     Fields:    Translation:AnimalsCells
    193. No association between genetic polymorphisms in IGF-I and IGFBP-3 and prostate cancer. Cancer Epidemiol Biomarkers Prev. 2004 Mar; 13(3):497-8. Li L, Cicek MS, Casey G, Witte JS. PMID: 15006930.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    194. DNA repair gene XRCC1 and XPD polymorphisms and risk of prostate cancer. Cancer Epidemiol Biomarkers Prev. 2004 Jan; 13(1):23-9. Rybicki BA, Conti DV, Moreira A, Cicek M, Casey G, Witte JS. PMID: 14744728.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    195. Comparison of missing data approaches in linkage analysis. BMC Genet. 2003 Dec 31; 4 Suppl 1:S44. Xing C, Schumacher FR, Conti DV, Witte JS. PMID: 14975112.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    196. Genome-wide scan of brothers: replication and fine mapping of prostate cancer susceptibility and aggressiveness loci. Prostate. 2003 Dec 01; 57(4):298-308. Witte JS, Suarez BK, Thiel B, Lin J, Yu A, Banerjee TK, Burmester JK, Casey G, Catalona WJ. PMID: 14601026.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    197. Relation of serum insulin-like growth factor-I (IGF-I) and IGF binding protein-3 to risk of prostate cancer (United States). Cancer Causes Control. 2003 Oct; 14(8):721-6. Li L, Yu H, Schumacher F, Casey G, Witte JS. PMID: 14674736.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    198. CYP3A4 and CYP3A5 genotypes, haplotypes, and risk of prostate cancer. Cancer Epidemiol Biomarkers Prev. 2003 Sep; 12(9):928-32. Plummer SJ, Conti DV, Paris PL, Curran AP, Casey G, Witte JS. PMID: 14504207.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    199. Prostate cancer aggressiveness locus on chromosome segment 19q12-q13.1 identified by linkage and allelic imbalance studies. Genes Chromosomes Cancer. 2003 Apr; 36(4):332-9. Neville PJ, Conti DV, Krumroy LM, Catalona WJ, Suarez BK, Witte JS, Casey G. PMID: 12619157.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    200. Hierarchical modeling of linkage disequilibrium: genetic structure and spatial relations. Am J Hum Genet. 2003 Feb; 72(2):351-63. Conti DV, Witte JS. PMID: 12525994.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    201. Haplotype tagging single nucleotide polymorphisms and association studies. Hum Hered. 2003; 56(1-3):48-55. Thompson D, Stram D, Goldgar D, Witte JS. PMID: 14614238.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    202. RNASEL Arg462Gln variant is implicated in up to 13% of prostate cancer cases. Nat Genet. 2002 Dec; 32(4):581-3. Casey G, Neville PJ, Plummer SJ, Xiang Y, Krumroy LM, Klein EA, Catalona WJ, Nupponen N, Carpten JD, Trent JM, Silverman RH, Witte JS. PMID: 12415269.
      View in: PubMed   Mentions: 106     Fields:    Translation:Humans
    203. Prostate cancer aggressiveness locus on chromosome 7q32-q33 identified by linkage and allelic imbalance studies. Neoplasia. 2002 Sep-Oct; 4(5):424-31. Neville PJ, Conti DV, Paris PL, Levin H, Catalona WJ, Suarez BK, Witte JS, Casey G. PMID: 12192601.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    204. Analysis of mutational spectra: locating hotspots and clusters of mutations using recursive segmentation. Stat Med. 2002 Jul 15; 21(13):1867-85. Fijal BA, Idury RM, Witte JS. PMID: 12111894.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    205. Point: population stratification: a problem for case-control studies of candidate-gene associations? Cancer Epidemiol Biomarkers Prev. 2002 Jun; 11(6):505-12. Thomas DC, Witte JS. PMID: 12050090.
      View in: PubMed   Mentions: 113     Fields:    Translation:Humans
    206. Androgen receptor CAG repeats and prostate cancer. Am J Epidemiol. 2002 May 15; 155(10):883-90. Nelson KA, Witte JS. PMID: 11994226.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    207. Relation between tumour necrosis factor polymorphism TNFalpha-308 and risk of asthma. Eur J Hum Genet. 2002 Jan; 10(1):82-5. Witte JS, Palmer LJ, O'Connor RD, Hopkins PJ, Hall JM. PMID: 11896460.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    208. Parametric linkage analysis. Methods Mol Biol. 2002; 195:13-35. Palmer LJ, Schnell AH, Witte JS, Elston RC. PMID: 12070879.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    209. Improvement of perineal wound healing by local administration of gentamicin-impregnated collagen fleeces after abdominoperineal excision of rectal cancer. Am J Surg. 2001 Nov; 182(5):502-9. Gruessner U, Clemens M, Pahlplatz PV, Sperling P, Witte J, Rosen HR. PMID: 11754859.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCellsCTClinical Trials
    210. [Ileus in colorectal carcinoma. Preoperative implantation of self-expanding metal stents and early elective surgery as an alternative to emergency surgery]. Chirurg. 2001 Oct; 72(10):1137-43. Knöpfle E, Mayer H, Wamser G, Bohndorf K, Witte J. PMID: 11715616.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansPHPublic Health
    211. Model-free linkage analysis with covariates confirms linkage of prostate cancer to chromosomes 1 and 4. Am J Hum Genet. 2001 May; 68(5):1197-206. Goddard KA, Witte JS, Suarez BK, Catalona WJ, Olson JM. PMID: 11309685.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    212. Is there any consensus in diagnostic and operative strategy with respect to medullary thyroid cancer? A questionnaire answered by 73 endocrine surgical units. Langenbecks Arch Surg. 2001 Feb; 386(1):47-52. Dotzenrath C, Goretzki PE, Cupisti K, Simon D, Witte J, Yang Q, Ohmann C, Röher HD. PMID: 11405089.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    213. Introduction: analysis of sequence data and population structure. Genet Epidemiol. 2001; 21 Suppl 1:S600-1. Witte JS, Fijal BA. PMID: 11793745.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    214. Predicting quantitative trait levels by modeling SNP interaction. Genet Epidemiol. 2001; 21 Suppl 1:S608-13. Fijal BA, Kim LL, Buxbaum SG, Witte JS. PMID: 11793747.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    215. Hierarchical modeling of the relation between sequence variants and a quantitative trait: addressing multiple comparison and population stratification issues. Genet Epidemiol. 2001; 21 Suppl 1:S668-73. Kim LL, Fijal BA, Witte JS. PMID: 11793759.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    216. Impact of preadjusting a quantitative phenotype prior to sib-pair linkage analysis when gene x environment interaction exists. Genet Epidemiol. 2001; 21 Suppl 1:S837-42. Mosley J, Conti DV, Elston RC, Witte JS. PMID: 11793789.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    217. Surgical treatment of postoperative, incidentally diagnosed small sporadic C-cell carcinomas of the thyroid. Langenbecks Arch Surg. 2000 Dec; 385(8):526-30. Cupisti K, Simon D, Wolf A, Gerharz CD, Goretzki PE, Dotzenrath C, Witte J, Röher HD. PMID: 11201009.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    218. Disease outcome in inflammatory bowel disease: mortality, morbidity and therapeutic management of a 796-person inception cohort in the European Collaborative Study on Inflammatory Bowel Disease (EC-IBD). Scand J Gastroenterol. 2000 Dec; 35(12):1272-7. Witte J, Shivananda S, Lennard-Jones JE, Beltrami M, Politi P, Bonanomi A, Tsianos EV, Mouzas I, Schulz TB, Monteiro E, Clofent J, Odes S, Limonard CB, Stockbrügger RW, Russel MG. PMID: 11199366.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    219. Surgery for Graves' disease: total versus subtotal thyroidectomy-results of a prospective randomized trial. World J Surg. 2000 Nov; 24(11):1303-11. Witte J, Goretzki PE, Dotzenrath C, Simon D, Felis P, Neubauer M, Röher HD. PMID: 11038198.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCTClinical Trials
    220. Multilevel modeling in epidemiology with GLIMMIX. Epidemiology. 2000 Nov; 11(6):684-8. Witte JS, Greenland S, Kim LL, Arab L. PMID: 11055630.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    221. Replication linkage study for prostate cancer susceptibility genes. Prostate. 2000 Oct 01; 45(2):106-14. Suarez BK, Lin J, Witte JS, Conti DV, Resnick MI, Klein EA, Burmester JK, Vaske DA, Banerjee TK, Catalona WJ. PMID: 11027409.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    222. Testing drug response in the presence of genetic information: sampling issues for clinical trials. Pharmacogenetics. 2000 Aug; 10(6):503-10. Cardon LR, Idury RM, Harris TJ, Witte JS, Elston RC. PMID: 10975604.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    223. [The AEP (Appropriateness Evaluation Protocol) procedure for the assessment of inpatient treatment needs. Evaluation from the surgery viewpoint]. Chirurg. 2000 Jul; 71(7):suppl 178-80. Bauer H, Witte J. PMID: 10986613.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    224. Identification and fine mapping of a region showing a high frequency of allelic imbalance on chromosome 16q23.2 that corresponds to a prostate cancer susceptibility locus. Cancer Res. 2000 Jul 01; 60(13):3645-9. Paris PL, Witte JS, Kupelian PA, Levin H, Klein EA, Catalona WJ, Casey G. PMID: 10910080.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    225. CYP3A activity in African American and European American men: population differences and functional effect of the CYP3A4*1B5'-promoter region polymorphism. Clin Pharmacol Ther. 2000 Jul; 68(1):82-91. Wandel C, Witte JS, Hall JM, Stein CM, Wood AJ, Wilkinson GR. PMID: 10945319.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
    226. Genomewide scan for prostate cancer-aggressiveness loci. Am J Hum Genet. 2000 Jul; 67(1):92-9. Witte JS, Goddard KA, Conti DV, Elston RC, Lin J, Suarez BK, Broman KW, Burmester JK, Weber JL, Catalona WJ. PMID: 10825281.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    227. A genome screen of multiplex sibships with prostate cancer. Am J Hum Genet. 2000 Mar; 66(3):933-44. Suarez BK, Lin J, Burmester JK, Broman KW, Weber JL, Banerjee TK, Goddard KA, Witte JS, Elston RC, Catalona WJ. PMID: 10712208.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    228. On the relative sample size required for multiple comparisons. Stat Med. 2000 Feb 15; 19(3):369-72. Witte JS, Elston RC, Cardon LR. PMID: 10649302.
      View in: PubMed   Mentions: 13     Fields:    
    229. Clinical trials in the genomic era: effects of protective genotypes on sample size and duration of trial. Control Clin Trials. 2000 Feb; 21(1):7-20. Fijal BA, Hall JM, Witte JS. PMID: 10660000.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    230. Linkage disequilibrium and allele-frequency distributions for 114 single-nucleotide polymorphisms in five populations. Am J Hum Genet. 2000 Jan; 66(1):216-34. Goddard KA, Hopkins PJ, Hall JM, Witte JS. PMID: 10631153.
      View in: PubMed   Mentions: 53     Fields:    Translation:Humans
    231. [Biatrial pacing as an effective therapy method of paroxysmal atrial fibrillation]. Wien Med Wochenschr. 2000; 150(19-21):419-23. Witte J, Reibis R, Bondke HJ, Baumann G. PMID: 11132436.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    232. Sleep apnea syndrome in patients with cardiac pacemaker. Respiration. 2000; 67(3):268-71. Fietze I, Röttig J, Quispe-Bravo S, Riedel F, Witte J, Baumann G, Witt C. PMID: 10867594.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    233. [Reproducibility of a German scale for assessing the need for inpatient treatment in surgery]. Soz Praventivmed. 2000; 45(6):258-66. Schneeweiss S, Sangha O, Siebert H, Hübner M, Fuhrmann J, Wildner M, Witte J. PMID: 11210596.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    234. Genetic mapping of complex traits. Stat Med. 1999 Nov 15; 18(21):2961-81. Olson JM, Witte JS, Elston RC. PMID: 10523753.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    235. Neonatal screening for hearing disorders in infants at risk: incidence, risk factors, and follow-up. Pediatrics. 1999 Oct; 104(4 Pt 1):900-4. Meyer C, Witte J, Hildmann A, Hennecke KH, Schunck KU, Maul K, Franke U, Fahnenstich H, Rabe H, Rossi R, Hartmann S, Gortner L. PMID: 10506232.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansPHPublic Health
    236. Association between a CYP3A4 genetic variant and clinical presentation in African-American prostate cancer patients. Cancer Epidemiol Biomarkers Prev. 1999 Oct; 8(10):901-5. Paris PL, Kupelian PA, Hall JM, Williams TL, Levin H, Klein EA, Casey G, Witte JS. PMID: 10548319.
      View in: PubMed   Mentions: 38     Fields:    Translation:Humans
    237. The health effects of swimming in ocean water contaminated by storm drain runoff. Epidemiology. 1999 Jul; 10(4):355-63. Haile RW, Witte JS, Gold M, Cressey R, McGee C, Millikan RC, Glasser A, Harawa N, Ervin C, Harmon P, Harper J, Dermand J, Alamillo J, Barrett K, Nides M, Wang G. PMID: 10401868.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCellsPHPublic Health
    238. Re: Biological aggressiveness of hereditary prostate cancer: long-term evaluation following radical prostatectomy. J Urol. 1999 May; 161(5):1585-6. Kupelian PA, Klein EA, Witte JS. PMID: 10210420.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    239. Asymptotic bias and efficiency in case-control studies of candidate genes and gene-environment interactions: basic family designs. Am J Epidemiol. 1999 Apr 15; 149(8):693-705. Witte JS, Gauderman WJ, Thomas DC. PMID: 10206618.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansPHPublic Health
    240. Likelihood-based approach to estimating twin concordance for dichotomous traits. Genet Epidemiol. 1999; 16(3):290-304. Witte JS, Carlin JB, Hopper JL. PMID: 10096691.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCTClinical Trials
    241. Model-based and model-free multipoint genome-wide linkage analysis of alcoholism. Genet Epidemiol. 1999; 17 Suppl 1:S175-80. Jacobs KB, Wedig GC, Schnell AH, Witte JS, Elston RC. PMID: 10597432.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    242. Family-based association studies. J Natl Cancer Inst Monogr. 1999; (26):31-7. Gauderman WJ, Witte JS, Thomas DC. PMID: 10854483.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    243. Does a family history of prostate cancer result in more aggressive disease? Prostate Cancer Prostatic Dis. 1998 Dec; 1(6):297-300. Klein EA, Kupelian PA, Witte JS. PMID: 12496870.
      View in: PubMed   Mentions: 2     Fields:    
    244. Software for hierarchical modeling of epidemiologic data. Epidemiology. 1998 Sep; 9(5):563-6. Witte JS, Greenland S, Kim LL. PMID: 9730038.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    245. Evaluating the performance of a genetic test using information from previous studies in place of a gold standard. Med Care. 1998 Aug; 36(8 Suppl):AS46-56. Fijal BA, Witte JS. PMID: 9708582.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    246. Glutathione transferase null genotype, broccoli, and lower prevalence of colorectal adenomas. Cancer Epidemiol Biomarkers Prev. 1998 Aug; 7(8):647-52. Lin HJ, Probst-Hensch NM, Louie AD, Kau IH, Witte JS, Ingles SA, Frankl HD, Lee ER, Haile RW. PMID: 9718215.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimals
    247. Monoclonal antibody therapy for resected Dukes' C colorectal cancer: seven-year outcome of a multicenter randomized trial. J Clin Oncol. 1998 May; 16(5):1788-94. Riethmüller G, Holz E, Schlimok G, Schmiegel W, Raab R, Höffken K, Gruber R, Funke I, Pichlmaier H, Hirche H, Buggisch P, Witte J, Pichlmayr R. PMID: 9586892.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansCTClinical Trials
    248. Familial prostate cancer: a different disease? J Urol. 1997 Dec; 158(6):2197-201. Kupelian PA, Klein EA, Witte JS, Kupelian VA, Suh JH. PMID: 9366343.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    249. A sigmoidoscopy-based case-control study of polyps: macronutrients, fiber and meat consumption. Int J Cancer. 1997 Nov 14; 73(4):497-502. Haile RW, Witte JS, Longnecker MP, Probst-Hensch N, Chen MJ, Harper J, Frankl HD, Lee ER. PMID: 9389562.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    250. A nested approach to evaluating dose-response and trend. Ann Epidemiol. 1997 Apr; 7(3):188-93. Witte JS, Greenland S. PMID: 9141641.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    251. Family history of prostate cancer in patients with localized prostate cancer: an independent predictor of treatment outcome. J Clin Oncol. 1997 Apr; 15(4):1478-80. Kupelian PA, Kupelian VA, Witte JS, Macklis R, Klein EA. PMID: 9193343.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    252. Plasma carotenoids and the prevalence of adenomatous polyps of the distal colon and rectum. Am J Epidemiol. 1997 Mar 15; 145(6):552-7. Shikany JM, Witte JS, Henning SM, Swendseid ME, Bird CL, Frankl HD, Lee ER, Haile RW. PMID: 9063346.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    253. Meat preparation and colorectal adenomas in a large sigmoidoscopy-based case-control study in California (United States). Cancer Causes Control. 1997 Mar; 8(2):175-83. Probst-Hensch NM, Sinha R, Longnecker MP, Witte JS, Ingles SA, Frankl HD, Lee ER, Haile RW. PMID: 9134241.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
    254. Diet and premenopausal bilateral breast cancer: a case-control study. Breast Cancer Res Treat. 1997 Feb; 42(3):243-51. Witte JS, Ursin G, Siemiatycki J, Thompson WD, Paganini-Hill A, Haile RW. PMID: 9065608.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    255. [Significance of lymph node metastases of differentiated thyroid gland carcinomas and C-cell carcinomas for prognosis--a meta-analysis]. Zentralbl Chir. 1997; 122(4):259-65. Witte J, Schlotmann U, Simon D, Dotzenrath C, Ohmann C, Goretzki PE. PMID: 9221636.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    256. Modeling age of onset and residual familial correlations for the linkage analysis of bipolar disorder. Genet Epidemiol. 1997; 14(6):675-80. Schnell AH, Karunaratne PM, Witte JS, Dawson DV, Elston RC. PMID: 9433562.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    257. Genetic analysis with hierarchical models. Genet Epidemiol. 1997; 14(6):1137-42. Witte JS. PMID: 9433637.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    258. Relation of vegetable, fruit, and grain consumption to colorectal adenomatous polyps. Am J Epidemiol. 1996 Dec 01; 144(11):1015-25. Witte JS, Longnecker MP, Bird CL, Lee ER, Frankl HD, Haile RW. PMID: 8942431.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimals
    259. Incidence of regional recurrence guiding radicality in differentiated thyroid carcinoma. World J Surg. 1996 Sep; 20(7):860-6; discussion 866. Simon D, Goretzki PE, Witte J, Röher HD. PMID: 8678963.
      View in: PubMed   Mentions: 38     Fields:    Translation:Humans
    260. Plasma ferritin, iron intake, and the risk of colorectal polyps. Am J Epidemiol. 1996 Jul 01; 144(1):34-41. Bird CL, Witte JS, Swendseid ME, Shikany JM, Hunt IF, Frankl HD, Lee ER, Longnecker MP, Haile RW. PMID: 8659483.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    261. Agreement in alcohol consumption levels as measured by two different questionnaires. J Stud Alcohol. 1996 Jul; 57(4):406-9. Witte JS, Haile RW. PMID: 8776682.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    262. Transmission of Mycobacterium tuberculosis from tuberculosis patients with HIV infection or AIDS. Am J Epidemiol. 1996 Jul 01; 144(1):69-77. Cauthen GM, Dooley SW, Onorato IM, Ihle WW, Burr JM, Bigler WJ, Witte J, Castro KG. PMID: 8659487.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansPHPublic Health
    263. Simulation study of hierarchical regression. Stat Med. 1996 Jun 15; 15(11):1161-70. Witte JS, Greenland S. PMID: 8804145.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    264. Genetic dissection of complex traits. Nat Genet. 1996 Apr; 12(4):355-6; author reply 357-8. Witte JS, Elston RC, Schork NJ. PMID: 8630483.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    265. Association within twin pairs for a dichotomous trait. Genet Epidemiol. 1996; 13(5):489-99. Olson JM, Witte JS, Elston RC. PMID: 8905395.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    266. A case-control study of reproductive variables, alcohol, and smoking in premenopausal bilateral breast cancer. Breast Cancer Res Treat. 1996; 37(1):49-56. Haile RW, Witte JS, Ursin G, Siemiatycki J, Bertolli J, Douglas Thompson W, Paganini-Hill A. PMID: 8750527.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    267. Red cell and plasma folate, folate consumption, and the risk of colorectal adenomatous polyps. Cancer Epidemiol Biomarkers Prev. 1995 Oct-Nov; 4(7):709-14. Bird CL, Swendseid ME, Witte JS, Shikany JM, Hunt IF, Frankl HD, Lee ER, Longnecker MP, Haile RW. PMID: 8672986.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    268. Re: "A population-based case-cohort evaluation of the efficacy of mammographic screening for breast cancer". Am J Epidemiol. 1995 Aug 15; 142(4):448-50. Langholz B, Thomas DC, Witte J, Peters RK. PMID: 7625412.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    269. Re: "Can energy adjustment separate the effects of energy from those of specific macronutrients?". Am J Epidemiol. 1995 Jul 15; 142(2):225-6. Witte JS, Pike MC. PMID: 7646721.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    270. Re: "Statistical significance testing in the American Journal of Epidemiology, 1970-1990". Am J Epidemiol. 1995 Jul 01; 142(1):101-3. Witte JS, Thomas DC, Langholz B. PMID: 7785668.
      View in: PubMed   Mentions:    Fields:    
    271. Genetic epidemiologic analysis of quantitative phenotypes using Gibbs sampling. Genet Epidemiol. 1995; 12(6):753-8. Gauderman WJ, Witte JS, Faucett CL, Morrison J, Thomas DC. PMID: 8788004.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    272. Hierarchical regression analysis applied to a study of multiple dietary exposures and breast cancer. Epidemiology. 1994 Nov; 5(6):612-21. Witte JS, Greenland S, Haile RW, Bird CL. PMID: 7841243.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    273. [Operative strategy in abdominal surgery in the aged: standard technics and alternatives]. Chirurg. 1984 Feb; 55(2):79-86. Witte J, Demmel N, Wirsching R, Denecke H. PMID: 6714014.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    274. [Physical performance of patients with fixed-frequency pacemaker with reference to hemodynamics, arteriovenous oxygen difference and pulmonary function]. Z Kardiol. 1974 Dec; 63(12):1099-110. Eimer HH, Witte J. PMID: 4458324.
      View in: PubMed   Mentions:    Fields:    Translation:Humans