Zachary Nevin • UCSF Profiles

Zachary Nevin, PhD

Title(s)	Scientist, Business Service Ctr
School	Chancellor/EVC/FAS
Address	555 Mission Bay Blvd South San Francisco CA 94158
ORCID	0000-0003-4987-924X
vCard	Download vCard

Biography

education and training

Gladstone Institutes, San Francisco, CA	Postdoc		Peripheral Neuropathy, iPSCs, CRISPR
Case Western Reserve University School of Medicine, Cleveland, OH	PhD	2018	Genetics and Genome Sciences
Stanford University, Stanford, CA	BS	2009	Biological Sciences

Overview

keywords

Induced Pluripotent Stem Cells, Neurons, Schwann Cells, Genome Engineering, CRISPR, Genetics, Neurogenetic Disease, Neuropathies, Charcot-Marie-Tooth, ALS, Leukodystrophies, Pelizaeus-Merzbacher Disease

webpage

Conklin Lab

Bibliographic

selected publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

Altmetrics Details

PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

Advances and challenges in modeling inherited peripheral neuropathies using iPSCs. Exp Mol Med. 2024 Jun; 56(6):1348-1364. Van Lent J, Prior R, Pérez Siles G, Cutrupi AN, Kennerson ML, Vangansewinkel T, Wolfs E, Mukherjee-Clavin B, Nevin Z, Judge L, Conklin B, Tyynismaa H, Clark AJ, Bennett DL, Van Den Bosch L, Saporta M, Timmerman V. PMID: 38825644; PMCID: PMC11263568.

View in: PubMed Mentions: 1 Fields:
Bio Biochemistry Mol Molecular Biology
Translation:Humans Animals Cells
A reference human induced pluripotent stem cell line for large-scale collaborative studies. Cell Stem Cell. 2022 12 01; 29(12):1685-1702.e22. Pantazis CB, Yang A, Lara E, McDonough JA, Blauwendraat C, Peng L, Oguro H, Kanaujiya J, Zou J, Sebesta D, Pratt G, Cross E, Blockwick J, Buxton P, Kinner-Bibeau L, Medura C, Tompkins C, Hughes S, Santiana M, Faghri F, Nalls MA, Vitale D, Ballard S, Qi YA, Ramos DM, Anderson KM, Stadler J, Narayan P, Papademetriou J, Reilly L, Nelson MP, Aggarwal S, Rosen LU, Kirwan P, Pisupati V, Coon SL, Scholz SW, Priebe T, Öttl M, Dong J, Meijer M, Janssen LJM, Lourenco VS, van der Kant R, Crusius D, Paquet D, Raulin AC, Bu G, Held A, Wainger BJ, Gabriele RMC, Casey JM, Wray S, Abu-Bonsrah D, Parish CL, Beccari MS, Cleveland DW, Li E, Rose IVL, Kampmann M, Calatayud Aristoy C, Verstreken P, Heinrich L, Chen MY, Schüle B, Dou D, Holzbaur ELF, Zanellati MC, Basundra R, Deshmukh M, Cohen S, Khanna R, Raman M, Nevin ZS, Matia M, Van Lent J, Timmerman V, Conklin BR, Johnson Chase K, Zhang K, Funes S, Bosco DA, Erlebach L, Welzer M, Kronenberg-Versteeg D, Lyu G, Arenas E, Coccia E, Sarrafha L, Ahfeldt T, Marioni JC, Skarnes WC, Cookson MR, Ward ME, Merkle FT. PMID: 36459969; PMCID: PMC9782786.

View in: PubMed Mentions: 71 Fields:
Cel Cell Biology
Suppression of proteolipid protein rescues Pelizaeus-Merzbacher disease. Nature. 2020 09; 585(7825):397-403. Elitt MS, Barbar L, Shick HE, Powers BE, Maeno-Hikichi Y, Madhavan M, Allan KC, Nawash BS, Gevorgyan AS, Hung S, Nevin ZS, Olsen HE, Hitomi M, Schlatzer DM, Zhao HT, Swayze A, LePage DF, Jiang W, Conlon RA, Rigo F, Tesar PJ. PMID: 32610343; PMCID: PMC7810164.

View in: PubMed Mentions: 36 Fields:
Sci Science
Translation:Animals Cells
Cell Type-Specific Intralocus Interactions Reveal Oligodendrocyte Mechanisms in MS. Cell. 2020 04 16; 181(2):382-395.e21. Factor DC, Barbeau AM, Allan KC, Hu LR, Madhavan M, Hoang AT, Hazel KEA, Hall PA, Nisraiyya S, Najm FJ, Miller TE, Nevin ZS, Karl RT, Lima BR, Song Y, Sibert AG, Dhillon GK, Volsko C, Bartels CF, Adams DJ, Dutta R, Gallagher MD, Phu W, Kozlenkov A, Dracheva S, Scacheri PC, Tesar PJ, Corradin O. PMID: 32246942; PMCID: PMC7426147.

View in: PubMed Mentions: 19 Fields:
Cel Cell Biology
Translation:Humans Animals Cells
Chemical Screening Identifies Enhancers of Mutant Oligodendrocyte Survival and Unmasks a Distinct Pathological Phase in Pelizaeus-Merzbacher Disease. Stem Cell Reports. 2018 09 11; 11(3):711-726. Elitt MS, Shick HE, Madhavan M, Allan KC, Clayton BLL, Weng C, Miller TE, Factor DC, Barbar L, Nawash BS, Nevin ZS, Lager AM, Li Y, Jin F, Adams DJ, Tesar PJ. PMID: 30146490; PMCID: PMC6135742.

View in: PubMed Mentions: 20 Fields:
Cel Cell Biology
Translation:Humans Animals Cells
Induction of myelinating oligodendrocytes in human cortical spheroids. Nat Methods. 2018 09; 15(9):700-706. Madhavan M, Nevin ZS, Shick HE, Garrison E, Clarkson-Paredes C, Karl M, Clayton BLL, Factor DC, Allan KC, Barbar L, Jain T, Douvaras P, Fossati V, Miller RH, Tesar PJ. PMID: 30046099; PMCID: PMC6508550.

View in: PubMed Mentions: 170 Fields:
Cli Clinical Laboratory Techniques
Translation:Humans Animals Cells
Accumulation of 8,9-unsaturated sterols drives oligodendrocyte formation and remyelination. Nature. 2018 08; 560(7718):372-376. Hubler Z, Allimuthu D, Bederman I, Elitt MS, Madhavan M, Allan KC, Shick HE, Garrison E, T Karl M, Factor DC, Nevin ZS, Sax JL, Thompson MA, Fedorov Y, Jin J, Wilson WK, Giera M, Bracher F, Miller RH, Tesar PJ, Adams DJ. PMID: 30046109; PMCID: PMC6423962.

View in: PubMed Mentions: 101 Fields:
Sci Science
Translation:Humans Animals Cells
Modeling the Mutational and Phenotypic Landscapes of Pelizaeus-Merzbacher Disease with Human iPSC-Derived Oligodendrocytes. Am J Hum Genet. 2017 Apr 06; 100(4):617-634. Nevin ZS, Factor DC, Karl RT, Douvaras P, Laukka J, Windrem MS, Goldman SA, Fossati V, Hobson GM, Tesar PJ. PMID: 28366443; PMCID: PMC5384098.

View in: PubMed Mentions: 28 Fields:
Gen Genetics
Translation:Humans Cells
Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo. Nature. 2015 Jun 11; 522(7555):216-20. Najm FJ, Madhavan M, Zaremba A, Shick E, Karl RT, Factor DC, Miller TE, Nevin ZS, Kantor C, Sargent A, Quick KL, Schlatzer DM, Tang H, Papoian R, Brimacombe KR, Shen M, Boxer MB, Jadhav A, Robinson AP, Podojil JR, Miller SD, Miller RH, Tesar PJ. PMID: 25896324; PMCID: PMC4528969.

View in: PubMed Mentions: 191 Fields:
Sci Science
Translation:Humans Animals Cells