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Luke Judge, MD, PhD

TitleAssistant Professor
SchoolUCSF School of Medicine
DepartmentPediatrics
Address550 16th. Street
San Francisco CA 94158
Phone415-476-3716
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoFellowship2014Neonatal-Perinatal Medicine
    University of California, San FranciscoResidency2011Pediatrics
    University of WashingtonM.D.2008Medicine
    University of WashingtonPh.D.2006Molecular and Cellular Biology
    Pomona CollegeB.A.1997Chemistry

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Judge L, Perez-Bermejo JA, Truong A, Ribeiro AJ, Yoo JC, Jensen CL, Mandegar MA, Huebsch N, Kaake RM, So PL, Srivastava D, Pruitt BL, Krogan NJ, Conklin BR. A BAG3 chaperone complex maintains cardiomyocyte function during proteotoxic stress. JCI Insight. 2017 Jul 20; 2(14). PMID: 28724793.
      View in: PubMed
    2. Huebsch N, Loskill P, Deveshwar N, Spencer CI, Judge L, Mandegar MA, B Fox C, Mohamed TM, Ma Z, Mathur A, Sheehan AM, Truong A, Saxton M, Yoo J, Srivastava D, Desai TA, So PL, Healy KE, Conklin BR. Miniaturized iPS-Cell-Derived Cardiac Muscles for Physiologically Relevant Drug Response Analyses. Sci Rep. 2016 Apr 20; 6:24726. PMID: 27095412; PMCID: PMC4837370.
    3. Mandegar MA, Huebsch N, Frolov EB, Shin E, Truong A, Olvera MP, Chan AH, Miyaoka Y, Holmes K, Spencer CI, Judge L, Gordon DE, Eskildsen TV, Villalta JE, Horlbeck MA, Gilbert LA, Krogan NJ, Sheikh SP, Weissman JS, Qi LS, So PL, Conklin BR. CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs. Cell Stem Cell. 2016 Apr 07; 18(4):541-53. PMID: 26971820; PMCID: PMC4830697 [Available on 04/07/17].
    4. Huebsch N, Loskill P, Mandegar MA, Marks NC, Sheehan AS, Ma Z, Mathur A, Nguyen TN, Yoo JC, Judge L, Spencer CI, Chukka AC, Russell CR, So PL, Conklin BR, Healy KE. Automated Video-Based Analysis of Contractility and Calcium Flux in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Cultured over Different Spatial Scales. Tissue Eng Part C Methods. 2015 May; 21(5):467-79. PMID: 25333967; PMCID: PMC4410286.
    5. Miyaoka Y, Chan AH, Judge L, Yoo J, Huang M, Nguyen TD, Lizarraga PP, So PL, Conklin BR. Isolation of single-base genome-edited human iPS cells without antibiotic selection. Nat Methods. 2014 Mar; 11(3):291-3. PMID: 24509632; PMCID: PMC4063274.
    6. Judge L, Arnett AL, Banks GB, Chamberlain JS. Expression of the dystrophin isoform Dp116 preserves functional muscle mass and extends lifespan without preventing dystrophy in severely dystrophic mice. Hum Mol Genet. 2011 Dec 15; 20(24):4978-90. PMID: 21949353; PMCID: PMC3221536.
    7. Banks GB, Judge L, Allen JM, Chamberlain JS. The polyproline site in hinge 2 influences the functional capacity of truncated dystrophins. PLoS Genet. 2010 May 20; 6(5):e1000958. PMID: 20502633; PMCID: PMC2873924.
    8. Li D, Bareja A, Judge L, Yue Y, Lai Y, Fairclough R, Davies KE, Chamberlain JS, Duan D. Sarcolemmal nNOS anchoring reveals a qualitative difference between dystrophin and utrophin. J Cell Sci. 2010 Jun 15; 123(Pt 12):2008-13. PMID: 20483958; PMCID: PMC2880012.
    9. Lai Y, Thomas GD, Yue Y, Yang HT, Li D, Long C, Judge L, Bostick B, Chamberlain JS, Terjung RL, Duan D. Dystrophins carrying spectrin-like repeats 16 and 17 anchor nNOS to the sarcolemma and enhance exercise performance in a mouse model of muscular dystrophy. J Clin Invest. 2009 Mar; 119(3):624-35. PMID: 19229108; PMCID: PMC2648692.
    10. Judge L, Haraguchiln M, Chamberlain JS. Dissecting the signaling and mechanical functions of the dystrophin-glycoprotein complex. J Cell Sci. 2006 Apr 15; 119(Pt 8):1537-46. PMID: 16569668.
      View in: PubMed
    11. Judge L, Chamberlain JS. Gene therapy for Duchenne muscular dystrophy: AAV leads the way. Acta Myol. 2005 Dec; 24(3):184-93. PMID: 16629052.
      View in: PubMed
    12. Andersen HS, Olsen OH, Iversen LF, Sørensen AL, Mortensen SB, Christensen MS, Branner S, Hansen TK, Lau JF, Jeppesen L, Moran EJ, Su J, Bakir F, Judge L, Shahbaz M, Collins T, Vo T, Newman MJ, Ripka WC, Møller NP. Discovery and SAR of a novel selective and orally bioavailable nonpeptide classical competitive inhibitor class of protein-tyrosine phosphatase 1B. J Med Chem. 2002 Sep 26; 45(20):4443-59. PMID: 12238924.
      View in: PubMed
    13. Niswender CM, Ishihara RW, Judge L, Zhang C, Shokat KM, McKnight GS. Protein engineering of protein kinase A catalytic subunits results in the acquisition of novel inhibitor sensitivity. J Biol Chem. 2002 Aug 09; 277(32):28916-22. PMID: 12034735.
      View in: PubMed
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