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    Mark Ratcliffe, MD

    TitleProfessor in Residence
    SchoolUCSF School of Medicine
    DepartmentSurgery
    Address4150 CLEMENT ST. (112)
    San Francisco CA 94121
    Phone415-750-2057

       Bibliographic 
       Publications
      Publications by year:
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      1. Shimkunas R, Zhang Z, Wenk JF, Soleimani M, Khazalpour M, Acevedo-Bolton G, Wang G, Saloner D, Mishra R, Wallace AW, Ge L, Baker AJ, Guccione JM, Ratcliffe MB. Left Ventricular Myocardial Contractility Is Depressed in the Borderzone After Posterolateral Myocardial Infarction. Ann Thorac Surg. 2013 Mar 20.
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      2. Ratcliffe M, Cambronero N, Ge L. Invited commentary. Ann Thorac Surg. 2013 Jan; 95(1):162.
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      3. Chitsaz S, Wenk JF, Ge L, Wisneski A, Mookhoek A, Ratcliffe MB, Guccione JM, Tseng EE. Material Properties of CorCap Passive Cardiac Support Device. Ann Thorac Surg. 2013 Jan; 95(1):148-54.
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      4. Wenk JF, Ratcliffe MB, Guccione JM. Finite element modeling of mitral leaflet tissue using a layered shell approximation. Med Biol Eng Comput. 2012 Oct; 50(10):1071-9.
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      5. Carrick R, Ge L, Lee LC, Zhang Z, Mishra R, Axel L, Guccione JM, Grossi EA, Ratcliffe MB. Patient-specific finite element-based analysis of ventricular myofiber stress after Coapsys: importance of residual stress. Ann Thorac Surg. 2012 Jun; 93(6):1964-71.
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      6. Zhang Z, Sun K, Saloner DA, Wallace AW, Ge L, Baker AJ, Guccione JM, Ratcliffe MB. The benefit of enhanced contractility in the infarct borderzone: a virtual experiment. Front Physiol. 2012; 3:86.
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      7. Wong VM, Wenk JF, Zhang Z, Cheng G, Acevedo-Bolton G, Burger M, Saloner DA, Wallace AW, Guccione JM, Ratcliffe MB, Ge L. The effect of mitral annuloplasty shape in ischemic mitral regurgitation: a finite element simulation. Ann Thorac Surg. 2012 Mar; 93(3):776-82.
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      8. Wall ST, Guccione JM, Ratcliffe MB, Sundnes JS. Electromechanical feedback with reduced cellular connectivity alters electrical activity in an infarct injured left ventricle: a finite element model study. Am J Physiol Heart Circ Physiol. 2012 Jan 1; 302(1):H206-14.
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      9. Wenk J, Guccione J, Ratcliffe M. Invited commentary. Ann Thorac Surg. 2011 Oct; 92(4):1442-3.
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      10. Soleimani M, Khazalpour M, Cheng G, Zhang Z, Acevedo-Bolton G, Saloner DA, Mishra R, Wallace AW, Guccione JM, Ge L, Ratcliffe MB. Moderate mitral regurgitation accelerates left ventricular remodeling after posterolateral myocardial infarction. Ann Thorac Surg. 2011 Nov; 92(5):1614-20.
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      11. Lee LC, Wenk JF, Klepach D, Zhang Z, Saloner D, Wallace AW, Ge L, Ratcliffe MB, Guccione JM. A novel method for quantifying in-vivo regional left ventricular myocardial contractility in the border zone of a myocardial infarction. J Biomech Eng. 2011 Sep; 133(9):094506.
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      12. Chitsaz S, Jaussaud N, Chau E, Yan KS, Azadani AN, Ratcliffe MB, Tseng EE. Operative risks and survival in veterans with severe aortic stenosis: surgery versus medical therapy. Ann Thorac Surg. 2011 Sep; 92(3):866-72.
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      13. Wenk JF, Eslami P, Zhang Z, Xu C, Kuhl E, Gorman JH, Robb JD, Ratcliffe MB, Gorman RC, Guccione JM. A novel method for quantifying the in-vivo mechanical effect of material injected into a myocardial infarction. Ann Thorac Surg. 2011 Sep; 92(3):935-41.
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      14. Mishra RK, Ratcliffe M. Invited commentary. Ann Thorac Surg. 2011 May; 91(5):1362-3.
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      15. Wenk JF, Sun K, Zhang Z, Soleimani M, Ge L, Saloner D, Wallace AW, Ratcliffe MB, Guccione JM. Regional left ventricular myocardial contractility and stress in a finite element model of posterobasal myocardial infarction. J Biomech Eng. 2011 Apr; 133(4):044501.
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      16. Zhang Z, Tendulkar A, Sun K, Saloner DA, Wallace AW, Ge L, Guccione JM, Ratcliffe MB. Comparison of the Young-Laplace law and finite element based calculation of ventricular wall stress: implications for postinfarct and surgical ventricular remodeling. Ann Thorac Surg. 2011 Jan; 91(1):150-6.
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      17. Wenk JF, Zhang Z, Cheng G, Malhotra D, Acevedo-Bolton G, Burger M, Suzuki T, Saloner DA, Wallace AW, Guccione JM, Ratcliffe MB. First finite element model of the left ventricle with mitral valve: insights into ischemic mitral regurgitation. Ann Thorac Surg. 2010 May; 89(5):1546-53.
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      18. Sun K, Zhang Z, Suzuki T, Wenk JF, Stander N, Einstein DR, Saloner DA, Wallace AW, Guccione JM, Ratcliffe MB. Dor procedure for dyskinetic anteroapical myocardial infarction fails to improve contractility in the border zone. J Thorac Cardiovasc Surg. 2010 Jul; 140(1):233-9, 239.e1-4.
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      19. Bakaeen FG, Chu D, Ratcliffe M, Gopaldas RR, Blaustein AS, Venkat R, Huh J, LeMaire SA, Coselli JS, Carabello BA. Severe aortic stenosis in a veteran population: treatment considerations and survival. Ann Thorac Surg. 2010 Feb; 89(2):453-8.
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      20. Jhun CS, Wenk JF, Zhang Z, Wall ST, Sun K, Sabbah HN, Ratcliffe MB, Guccione JM. Effect of adjustable passive constraint on the failing left ventricle: a finite-element model study. Ann Thorac Surg. 2010 Jan; 89(1):132-7.
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      21. Wenk JF, Wall ST, Peterson RC, Helgerson SL, Sabbah HN, Burger M, Stander N, Ratcliffe MB, Guccione JM. A method for automatically optimizing medical devices for treating heart failure: designing polymeric injection patterns. J Biomech Eng. 2009 Dec; 131(12):121011.
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      22. Sun K, Stander N, Jhun CS, Zhang Z, Suzuki T, Wang GY, Saeed M, Wallace AW, Tseng EE, Baker AJ, Saloner D, Einstein DR, Ratcliffe MB, Guccione JM. A computationally efficient formal optimization of regional myocardial contractility in a sheep with left ventricular aneurysm. J Biomech Eng. 2009 Nov; 131(11):111001.
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      23. Carson JP, Kuprat AP, Jiao X, Dyedov V, Del Pin F, Guccione JM, Ratcliffe MB, Einstein DR. Adaptive generation of multimaterial grids from imaging data for biomedical Lagrangian fluid-structure simulations. Biomech Model Mechanobiol. 2010 Apr; 9(2):187-201.
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      24. Ge L, Ratcliffe M. The use of computational flow modeling (CFD) to determine the effect of left ventricular shape on blood flow in the left ventricle. Ann Thorac Surg. 2009 Apr; 87(4):993-4.
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      25. Gundiah N, Ratcliffe MB, Pruitt LA. The biomechanics of arterial elastin. J Mech Behav Biomed Mater. 2009 Jul; 2(3):288-96.
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      26. Guy TS, Tseng E, Ratcliffe MB, Azakie A, Karl TR. A simple correction for anomalous coronary arteries in adults. J Thorac Cardiovasc Surg. 2009 Jan; 137(1):e50-1.
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      27. Ratcliffe MB, Howard C, Mann M, del Nido P. National Institutes of Health funding for cardiothoracic surgical research. J Thorac Cardiovasc Surg. 2008 Aug; 136(2):392-7; discussion 398-9.
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      28. Walker JC, Ratcliffe MB, Zhang P, Wallace AW, Hsu EW, Saloner DA, Guccione JM. Magnetic resonance imaging-based finite element stress analysis after linear repair of left ventricular aneurysm. J Thorac Cardiovasc Surg. 2008 May; 135(5):1094-102, 1102.e1-2.
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      29. Gundiah N, Kam K, Matthews PB, Guccione J, Dwyer HA, Saloner D, Chuter TA, Guy TS, Ratcliffe MB, Tseng EE. Asymmetric mechanical properties of porcine aortic sinuses. Ann Thorac Surg. 2008 May; 85(5):1631-8.
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      30. Mann M, Tendulkar A, Birger N, Howard C, Ratcliffe MB. National institutes of health funding for surgical research. Ann Surg. 2008 Feb; 247(2):217-21.
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      31. Knapp M, Windmeijer F, Brown J, Kontodimas S, Tzivelekis S, Haro JM, Ratcliffe M, Hong J, Novick D. Cost-utility analysis of treatment with olanzapine compared with other antipsychotic treatments in patients with schizophrenia in the pan-European SOHO study. Pharmacoeconomics. 2008; 26(4):341-58.
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      32. Zhang P, Guccione JM, Nicholas SI, Walker JC, Crawford PC, Shamal A, Acevedo-Bolton G, Guttman MA, Ozturk C, McVeigh ER, Saloner DA, Wallace AW, Ratcliffe MB. Endoventricular patch plasty for dyskinetic anteroapical left ventricular aneurysm increases systolic circumferential shortening in sheep. J Thorac Cardiovasc Surg. 2007 Oct; 134(4):1017-24.
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      33. Ratcliffe MB, Guy TS. The effect of preoperative diastolic dysfunction on outcome after surgical ventricular remodeling. J Thorac Cardiovasc Surg. 2007 Aug; 134(2):280-3.
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      34. Ratcliffe MB. Invited commentary. Ann Thorac Surg. 2007 Jul; 84(1):101-2.
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      35. Jiang Y, Guccione JM, Ratcliffe MB, Hsu EW. Transmural heterogeneity of diffusion anisotropy in the sheep myocardium characterized by MR diffusion tensor imaging. Am J Physiol Heart Circ Physiol. 2007 Oct; 293(4):H2377-84.
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      36. Haro JM, Novick D, Suarez D, Alonso J, Lépine JP, Ratcliffe M. Remission and relapse in the outpatient care of schizophrenia: three-year results from the Schizophrenia Outpatient Health Outcomes study. J Clin Psychopharmacol. 2006 Dec; 26(6):571-8.
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      37. Wall ST, Walker JC, Healy KE, Ratcliffe MB, Guccione JM. Theoretical impact of the injection of material into the myocardium: a finite element model simulation. Circulation. 2006 Dec 12; 114(24):2627-35.
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      38. Ratcliffe MB. The treatment of ischemic heart failure with surgical ventricular restoration (SVR): new evidence of benefit. J Card Fail. 2006 Apr; 12(3):195-8.
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      39. Guccione JM, Walker JC, Beitler JR, Moonly SM, Zhang P, Guttman MA, Ozturk C, McVeigh ER, Wallace AW, Saloner DA, Ratcliffe MB. The effect of anteroapical aneurysm plication on end-systolic three-dimensional strain in the sheep: a magnetic resonance imaging tagging study. J Thorac Cardiovasc Surg. 2006 Mar; 131(3):579-586.e3.
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      40. Zhang P, Guccione JM, Nicholas SI, Walker JC, Crawford PC, Shamal A, Saloner DA, Wallace AW, Ratcliffe MB. Left ventricular volume and function after endoventricular patch plasty for dyskinetic anteroapical left ventricular aneurysm in sheep. J Thorac Cardiovasc Surg. 2005 Oct; 130(4):1032-8.
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      41. Walker JC, Ratcliffe MB, Zhang P, Wallace AW, Fata B, Hsu EW, Saloner D, Guccione JM. MRI-based finite-element analysis of left ventricular aneurysm. Am J Physiol Heart Circ Physiol. 2005 Aug; 289(2):H692-700.
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      42. Mann MJ, Tseng E, Ratcliffe M, Strattman G, De Silva A, Demarco T, Achorn N, Moskalik W, Hoopes C. Use of bivalirudin, a direct thrombin inhibitor, and its reversal with modified ultrafiltration during heart transplantation in a patient with heparin-induced thrombocytopenia. J Heart Lung Transplant. 2005 Feb; 24(2):222-5.
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      43. Walker JC, Guccione JM, Jiang Y, Zhang P, Wallace AW, Hsu EW, Ratcliffe MB. Helical myofiber orientation after myocardial infarction and left ventricular surgical restoration in sheep. J Thorac Cardiovasc Surg. 2005 Feb; 129(2):382-90.
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      44. Dang AB, Guccione JM, Zhang P, Wallace AW, Gorman RC, Gorman JH, Ratcliffe MB. Effect of ventricular size and patch stiffness in surgical anterior ventricular restoration: a finite element model study. Ann Thorac Surg. 2005 Jan; 79(1):185-93.
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      45. Dang AB, Guccione JM, Mishell JM, Zhang P, Wallace AW, Gorman RC, Gorman JH, Ratcliffe MB. Akinetic myocardial infarcts must contain contracting myocytes: finite-element model study. Am J Physiol Heart Circ Physiol. 2005 Apr; 288(4):H1844-50.
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      46. Guccione JM, Salahieh A, Moonly SM, Kortsmit J, Wallace AW, Ratcliffe MB. Myosplint decreases wall stress without depressing function in the failing heart: a finite element model study. Ann Thorac Surg. 2003 Oct; 76(4):1171-80; discussion 1180.
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      47. Quarterman RL, McMillan A, Ratcliffe MB, Block MI. Effect of preoperative delay on prognosis for patients with early stage non-small cell lung cancer. J Thorac Cardiovasc Surg. 2003 Jan; 125(1):108-13; discussion 113-4.
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      48. Quarterman RL, Moonly S, Wallace AW, Guccione J, Ratcliffe MB. A finite element model of left ventricular cellular transplantation in dilated cardiomyopathy. ASAIO J. 2002 Sep-Oct; 48(5):508-13.
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      49. Teerlink JR, Ratcliffe MB. Ventricular remodeling surgery for heart failure: small animals and how to measure an improvement in ventricular function. Ann Thorac Surg. 2002 May; 73(5):1368-70.
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      50. Victal OA, Teerlink JR, Gaxiola E, Wallace AW, Najar S, Camacho DH, Gutierrez A, Herrera G, Zuniga G, Mercado-Rios F, Ratcliffe MB. Left ventricular volume reduction by radiofrequency heating of chronic myocardial infarction in patients with congestive heart failure. Circulation. 2002 Mar 19; 105(11):1317-22.
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      51. Guccione JM, Moonly SM, Wallace AW, Ratcliffe MB. Residual stress produced by ventricular volume reduction surgery has little effect on ventricular function and mechanics: a finite element model study. J Thorac Cardiovasc Surg. 2001 Sep; 122(3):592-9.
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      52. Guccione JM, Moonly SM, Moustakidis P, Costa KD, Moulton MJ, Ratcliffe MB, Pasque MK. Mechanism underlying mechanical dysfunction in the border zone of left ventricular aneurysm: a finite element model study. Ann Thorac Surg. 2001 Feb; 71(2):654-62.
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      53. Ratcliffe M. Batista's operation: what have we learned? J Am Coll Cardiol. 2000 Dec; 36(7):2115-8.
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      54. Wallace AW, Ratcliffe MB, Nosé PS, Bellows W, Moores W, McEnany MT, Flachsbart K, Mangano DT. Effect of induction and reperfusion with warm substrate-enriched cardioplegia on ventricular function. Ann Thorac Surg. 2000 Oct; 70(4):1301-7.
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      55. Ratcliffe MB, Wallace AW, Teerlink JR, Hong J, Salahieh A, Sung SH, Keung EC, Lee RJ. Radio frequency heating of chronic ovine infarct leads to sustained infarct area and ventricular volume reduction. J Thorac Cardiovasc Surg. 2000 Jun; 119(6):1194-204.
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      56. Ratcliffe MB, Khan JH, Magee KM, McElhinney DB, Hubner C. Collection of process data after cardiac surgery: initial implementation with a Java-based intranet applet. Ann Thorac Surg. 2000 Jun; 69(6):1817-21; discussion 1821-2.
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      57. Ratcliffe MB, Hong J, Salahieh A, Wallace AW. The effect of diastolic stiffness on ventricular function after partial ventriculectomy: a finite element simulation. ASAIO J. 2000 Jan-Feb; 46(1):111-6.
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      58. Ratcliffe MB, Wallace AW, Salahieh A, Hong J, Ruch S, Hall TS. Ventricular volume, chamber stiffness, and function after anteroapical aneurysm plication in the sheep. J Thorac Cardiovasc Surg. 2000 Jan; 119(1):115-24.
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      59. Wallace AW, Ratcliffe MB, Galindez D, Kong JS. L-arginine infusion dilates coronary vasculature in patients undergoing coronary bypass surgery. Anesthesiology. 1999 Jun; 90(6):1577-86.
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      60. Ratcliffe MB, Hong J, Salahieh A, Ruch S, Wallace AW. The effect of ventricular volume reduction surgery in the dilated, poorly contractile left ventricle: a simple finite element analysis. J Thorac Cardiovasc Surg. 1998 Oct; 116(4):566-77.
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      61. Gorman JH, Gupta KB, Streicher JT, Gorman RC, Jackson BM, Ratcliffe MB, Bogen DK, Edmunds LH. Dynamic three-dimensional imaging of the mitral valve and left ventricle by rapid sonomicrometry array localization. J Thorac Cardiovasc Surg. 1996 Sep; 112(3):712-26.
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      62. Ratcliffe MB, Gupta KB, Streicher JT, Savage EB, Bogen DK, Edmunds LH. Use of sonomicrometry and multidimensional scaling to determine the three-dimensional coordinates of multiple cardiac locations: feasibility and initial implementation. IEEE Trans Biomed Eng. 1995 Jun; 42(6):587-98.
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      63. Gorman RC, McCaughan JS, Ratcliffe MB, Gupta KB, Streicher JT, Ferrari VA, St John-Sutton MG, Bogen DK, Edmunds LH. Pathogenesis of acute ischemic mitral regurgitation in three dimensions. J Thorac Cardiovasc Surg. 1995 Apr; 109(4):684-93.
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      64. Lefer DJ, Flynn DM, Phillips ML, Ratcliffe M, Buda AJ. A novel sialyl LewisX analog attenuates neutrophil accumulation and myocardial necrosis after ischemia and reperfusion. Circulation. 1994 Nov; 90(5):2390-401.
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      65. Gupta KB, Ratcliffe MB, Fallert MA, Edmunds LH, Bogen DK. Changes in passive mechanical stiffness of myocardial tissue with aneurysm formation. Circulation. 1994 May; 89(5):2315-26.
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      66. Edmunds LH, Herrmann HC, DiSesa VJ, Ratcliffe MB, Bavaria JE, McCarthy DM. Left ventricular assist without thoracotomy: clinical experience with the Dennis method. Ann Thorac Surg. 1994 Apr; 57(4):880-5.
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      67. Llaneras MR, Nance ML, Streicher JT, Lima JA, Savino JS, Bogen DK, Deac RF, Ratcliffe MB, Edmunds LH. Large animal model of ischemic mitral regurgitation. Ann Thorac Surg. 1994 Feb; 57(2):432-9.
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      68. Savage EB, Downing SW, Ratcliffe MB, Fallert M, Gupta KB, Tyson GS, Bogen DK, Edmunds LH. Repair of left ventricular aneurysm. Changes in ventricular mechanics, hemodynamics, and oxygen consumption. J Thorac Cardiovasc Surg. 1992 Sep; 104(3):752-62.
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      69. Ratcliffe MB, Bavaria JE, Wenger RK, Bogen DK, Edmunds LH. Left ventricular mechanics of ejecting, postischemic hearts during left ventricular circulatory assistance. J Thorac Cardiovasc Surg. 1991 Feb; 101(2):245-55.
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      70. Bavaria JE, Furukawa S, Kreiner G, Ratcliffe MB, Streicher J, Bogen DK, Edmunds LH. Myocardial oxygen utilization after reversible global ischemia. J Thorac Cardiovasc Surg. 1990 Aug; 100(2):210-20.
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      71. Markovitz LJ, Savage EB, Ratcliffe MB, Bavaria JE, Kreiner G, Iozzo RV, Hargrove WC, Bogen DK, Edmunds LH. Large animal model of left ventricular aneurysm. Ann Thorac Surg. 1989 Dec; 48(6):838-45.
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      72. Gupta KB, Bavaria JE, Ratcliffe MB, Edmunds LH, Bogen DK. Measurement of end-systolic pressure-volume relations by intra-aortic balloon occlusion. Circulation. 1989 Oct; 80(4):1016-28.
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      73. Stephenson LW, Hargrove WC, Ratcliffe MB, Edmunds LH. Surgery for left ventricular aneurysm. Early survival with and without endocardial resection. Circulation. 1989 Jun; 79(6 Pt 2):I108-11.
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      74. Wenger RK, Bavaria JE, Ratcliffe MB, Bogen D, Edmunds LH. Flow dynamics of peripheral venous catheters during extracorporeal membrane oxygenation with a centrifugal pump. J Thorac Cardiovasc Surg. 1988 Sep; 96(3):478-84.
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      75. Bavaria JE, Ratcliffe MB, Gupta KB, Wenger RK, Bogen DK, Edmunds LH. Changes in left ventricular systolic wall stress during biventricular circulatory assistance. Ann Thorac Surg. 1988 May; 45(5):526-32.
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