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    Won-Tak Choi, MD, PhD

    TitleAssistant Professor
    SchoolUCSF School of Medicine
    DepartmentPathology
    Address505 Parnassus Avenue
    San Francisco CA 94117
    Phone415-476-1613
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      Collapse Biography 
      Collapse Education and Training
      University of Illinois MD, PhDMedicine 2009
      University of California at San FranciscoResidencyOB/GYN2010
      Scripps Research Institute Post-Doctoral Research FellowImmunology2011
      University of Washington ResidencyPathology2015
      University of California at San Francisco FellowshipPathology2016

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      Collapse Featured Publications

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Choi WT, Cherian S, Soma L. . Significance of CD10-positive clonal B cell populations identified by flow cytometry in histologically benign gastric biopsies. J Hematop. 2016; 9(2):59-66.
      2. Choi WT, Chang TT, Gill RM. Gastrointestinal Zygomycosis Masquerading as Acute Appendicitis. Case Rep Gastroenterol. 2016 Jan-Apr; 10(1):81-7. PMID: 27403107.
        View in: PubMed
      3. Choi WT, Swanson PE, Grieco VS, Wang D, Westerhoff M. The outcomes of "atypical" and "suspicious" bile duct brushings in the identification of pancreaticobiliary tumors: Follow-up analysis of surgical resection specimens. Diagn Cytopathol. 2015 Nov; 43(11):885-91. PMID: 26221777.
        View in: PubMed
      4. Choi WT, Rabinovitch PS, Wang D, Westerhoff M. Outcome of "indefinite for dysplasia" in inflammatory bowel disease: correlation with DNA flow cytometry and other risk factors of colorectal cancer. Hum Pathol. 2015 Jul; 46(7):939-47. PMID: 25962315.
        View in: PubMed
      5. Choi WT, Emond MJ, Rabinovitch PS, Ahn J, Upton MP, Westerhoff M. "Indefinite for Dysplasia" in Barrett's Esophagus: Inflammation and DNA Content Abnormality are Significant Predictors of Early Detection of Neoplasia. Clin Transl Gastroenterol. 2015; 6:e81. PMID: 25761942; PMCID: PMC4459537.
      6. Choi WT, Yang Y, Xu Y, An J. Targeting chemokine receptor CXCR4 for treatment of HIV-1 infection, tumor progression, and metastasis. Curr Top Med Chem. 2014; 14(13):1574-89. PMID: 25159167; PMCID: PMC4372248.
      7. Choi WT, Stetsenko GY, Zhang J, Olerud JE, Argenyi ZB, George E. Cutaneous angiosarcoma clinically presenting as progressive solid facial edema in a 43-year-old male. Dermatol Online J. 2013 Nov; 19(11):20409. PMID: 24314784.
        View in: PubMed
      8. Choi WT, Kumar S, Madani N, Han X, Tian S, Dong CZ, Liu D, Duggineni S, Yuan J, Sodroski JG, Huang Z, An J. A novel synthetic bivalent ligand to probe chemokine receptor CXCR4 dimerization and inhibit HIV-1 entry. Biochemistry. 2012 Sep 11; 51(36):7078-86. PMID: 22897429; PMCID: PMC3476724.
      9. Dong CZ, Tian S, Choi WT, Kumar S, Liu D, Xu Y, Han X, Huang Z, An J. Critical role in CXCR4 signaling and internalization of the polypeptide main chain in the amino terminus of SDF-1a probed by novel N-methylated synthetically and modularly modified chemokine analogues. Biochemistry. 2012 Jul 31; 51(30):5951-7. PMID: 22779681; PMCID: PMC3891921.
      10. Choi WT, Nedellec R, Coetzer M, Colin P, Lagane B, Offord RE, Hartley O, Mosier DE. CCR5 mutations distinguish N-terminal modifications of RANTES (CCL5) with agonist versus antagonist activity. J Virol. 2012 Sep; 86(18):10218-20. PMID: 22787219; PMCID: PMC3446584.
      11. Choi WT, Duggineni S, Xu Y, Huang Z, An J. Drug discovery research targeting the CXC chemokine receptor 4 (CXCR4). J Med Chem. 2012 Feb 9; 55(3):977-94. PMID: 22085380; PMCID: PMC3476736.
      12. Dong CZ, Tian S, Madani N, Choi WT, Kumar S, Liu D, Sodroski JG, Huang Z, An J. Role of CXCR4 internalization in the anti-HIV activity of stromal cell-derived factor-1a probed by a novel synthetically and modularly modified-chemokine analog. Exp Biol Med (Maywood). 2011 Dec; 236(12):1413-9. PMID: 22101518; PMCID: PMC3752462.
      13. Choi WT, An J. Biology and clinical relevance of chemokines and chemokine receptors CXCR4 and CCR5 in human diseases. Exp Biol Med (Maywood). 2011 Jun 1; 236(6):637-47. PMID: 21565895; PMCID: PMC3932662.
      14. Liu D, Madani N, Li Y, Cao R, Choi WT, Kawatkar SP, Lim MY, Kumar S, Dong CZ, Wang J, Russell JD, Lefebure CR, An J, Wilson S, Gao YG, Pallansch LA, Sodroski JG, Huang Z. Crystal structure and structural mechanism of a novel anti-human immunodeficiency virus and D-amino acid-containing chemokine. J Virol. 2007 Oct; 81(20):11489-98. PMID: 17686848; PMCID: PMC2045531.
      15. Choi WT, Kaul M, Kumar S, Wang J, Kumar IM, Dong CZ, An J, Lipton SA, Huang Z. Neuronal apoptotic signaling pathways probed and intervened by synthetically and modularly modified (SMM) chemokines. J Biol Chem. 2007 Mar 9; 282(10):7154-63. PMID: 17218311.
        View in: PubMed
      16. Wang J, Kumar S, Choi WT, Dong C, Huang Z. Design and synthesis of novel chemokine analogs derived from vMIP-II. Protein Pept Lett. 2006; 13(5):499-501. PMID: 16800805.
        View in: PubMed
      17. Kumar S, Choi WT, Dong CZ, Madani N, Tian S, Liu D, Wang Y, Pesavento J, Wang J, Fan X, Yuan J, Fritzsche WR, An J, Sodroski JG, Richman DD, Huang Z. SMM-chemokines: a class of unnatural synthetic molecules as chemical probes of chemokine receptor biology and leads for therapeutic development. Chem Biol. 2006 Jan; 13(1):69-79. PMID: 16426973.
        View in: PubMed
      18. Dong CZ, Kumar S, Choi WT, Madani N, Tian S, An J, Sodroski JG, Huang Z. Different stereochemical requirements for CXCR4 binding and signaling functions as revealed by an anti-HIV, D-amino acid-containing SMM-chemokine ligand. J Med Chem. 2005 Dec 15; 48(25):7923-4. PMID: 16335916.
        View in: PubMed
      19. Choi WT, Tian S, Dong CZ, Kumar S, Liu D, Madani N, An J, Sodroski JG, Huang Z. Unique ligand binding sites on CXCR4 probed by a chemical biology approach: implications for the design of selective human immunodeficiency virus type 1 inhibitors. J Virol. 2005 Dec; 79(24):15398-404. PMID: 16306611; PMCID: PMC1316031.
      20. Tian S, Choi WT, Liu D, Pesavento J, Wang Y, An J, Sodroski JG, Huang Z. Distinct functional sites for human immunodeficiency virus type 1 and stromal cell-derived factor 1alpha on CXCR4 transmembrane helical domains. J Virol. 2005 Oct; 79(20):12667-73. PMID: 16188969; PMCID: PMC1235829.
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