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Aleksandar Rajkovic, PhD, MD

Title(s)Professor, Pathology
SchoolSchool of Medicine
Address513 Parnassus Ave, HSE
San Francisco CA 94143
Phone415-502-4961
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    Collapse Biography 
    Collapse Education and Training
    Johns Hopkins University, Baltimore, MarylandBS1985Chemistry
    Case Western Reserve University, Cleveland, OhioMD/PhD1992Medicine/Molecular Biology
    Metrohealth Medical Center, Cleveland, OhioInternship, General Medicine1993Internal Medicine
    Metrohealth Medical Center, Cleveland, OhioResidency1997Obstetrics and Gynecology
    Metrohealth Medical Cente, Cleveland, OhioFellowship1997Maternal Fetal Medicine
    Baylor College of Medicine, Houston, TexasMedical Genetic Residency1999Medical Genetics

    Collapse Overview 
    Collapse Overview
    Aleksandar Rajkovic is a Professor of Pathology and Obstetrics/Gynecology and Reproductive Sciences. He is a Stuart Lindsay Distinguished Professor in Experimental Pathology I. He serves as the UCSF Chief Genomics Officer and is the Medical Director and Chief of the Center for Genetic and Genomic Medicine (CGGM) that organizes, coordinates and oversees Clinical Genetics and Genomics Services across the entire UCSF Health System. He also serves as the Director of the Genomic Medicine Initiative.

    Rajkovic lab investigates the genetic underpinnings of the formation and differentiation of gametes and reproductive tract, their role of these genes in human disease, embryo lethality and origin of heritable human disorders. The lab studies transcriptional regulation of ovarian follicle activation and oocyte survival and how these processes are essential to produce healthy egg. Early stages of ovarian follicle formation, beginning with the breakdown of germ cell cysts, formation of primordial follicles and transition to primary and secondary follicles, are critical in determining the reproductive life span and fertility. Transcription of numerous germ cell specific genes, necessary and essential for follicular development, is initiated during these early stages of follicle formation. With mouse models, his laboratory discovered numerous transcriptional regulators such as Sohlh1, Sohlh2, Lhx8, and Nobox that regulate gamete development and reproductive tract development. These transcription factors are necessary to drive oocyte growth, and synthesis of maternal effect genes that are essential for early embryogenesis and are likely involved in setting of epigenetic marks. Mutations in these oocyte-specific transcriptional regulators associate with human condition of premature ovarian insufficiency and infertility, emphasizing the importance of these pathways to women’s health. Recent epidemiologic studies have suggested that reproductive tract development abnormalities and associated pathologies such as infertility, ovarian insufficiency and premature menopause are associated with higher mortality and morbidity. Whole genome human studies in his laboratory discovered that DNA damage repair genes such as MCM8 and MCM9 are mutated in women with infertility and the lab is exploring the link between DNA damage repair genes with infertility phenotypes and accelerated overall aging, as well as the effect of these genes on the overall health of offspring and genesis of structural birth defects. These and other studies indicate that many of the reproductive disorders are developmental in origin.

    The lab is also investigating the genetic underpinnings of uterine leiomyomas, better known as fibroid tumors. Fibroid tumors are clinically apparent in nearly 25% of women by age 45, and they cause major morbidity in American women. We have discovered numerous genomic rearrangements that associate with this tumor and we also discovered that 70% of American women harbor mutations within one gene, MED12, regardless of the karyotype abnormality of the tumors. We are currently investigating the mechanisms of MED12 action in leiomyomas and therapies directed towards eliminating such tumors in symptomatic women.

    The lab has also been at the forefront of applying cutting edge OMICS technologies to diagnosing infertility, gonadal dysgenesis, and prenatal disorders. The lab made significant contributions to non-invasive diagnosis of submicroscopic deletions, design and utility of dense X chromosome arrays, and utility of genomewide detection of copy number variants in prenatal diagnosis among others. The lab is currently investigating non-invasive OMICS both prior and post-implantation to predict and prevent human disorders.

    Collapse Research 
    Collapse Research Activities and Funding
    The Origin and cellular heterogeneity of uterine leiomyomas
    NICHD P50 HD098580 01Apr 1, 2019 - Mar 31, 2024
    Role: Principal Investigator
    Project 2 PI: The Origin and Cellular Heterogeneity of Uterine Leiomyomas
    P50 HD098580-01Apr 1, 2019 - Mar 31, 2024
    Small molecule GPR10 antagonists for the treatment of uterine fibroids
    NIH/NICHD R01HD094373Aug 8, 2018 - Jul 31, 2020
    Role: Co-Principal Investigator
    Med12 mechanisms of uterine leiomyoma formation
    NIH/NICHD R01HD088629Jul 1, 2017 - Jun 30, 2022
    Role: Principal Investigator
    Genomic integrity of the X chromosome &Ovary-Specific Autosomal Genes
    NIH/NICHD R21HD074278May 1, 2014 - Apr 30, 2016
    Role: Principal Investigator
    Genomic Basis of Premature Ovarian Insufficiency
    NIH/NICHD R01HD070647Apr 1, 2012 - Jan 31, 2017
    Role: Principal Investigator
    LIM Homeodomain Regulated Genetic Pathways in Oogenesis and Ovarian Failure
    NIH/NICHD R01HD056351Sep 30, 2009 - Aug 31, 2012
    Role: Principal Investigator
    THE ROLE OF HORMAD1 IN GERM CELL DEVELOPMENT AND MEIOSIS
    NIH/NICHD R03HD054829Sep 4, 2009 - Jul 31, 2011
    Role: Principal Investigator
    Genetics of Human Ovarian Failure
    NIH/NICHD R21HD058125Apr 11, 2008 - May 1, 2010
    Role: Principal Investigator
    The role of Obox in mammalian oogenesis
    NIH/NICHD R03HD047514Aug 1, 2004 - Jul 31, 2006
    Role: Principal Investigator
    Transcriptional Regulation of Early Folliculogenesis
    NIH/NICHD R01HD044858Apr 1, 2004 - Mar 31, 2010
    Role: Principal Investigator

    Collapse ORNG Applications 
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    Collapse In The News

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Female reproductive tract has low concentration of SARS-CoV2 receptors. bioRxiv. 2020 Jun 22. Goad J, Rudolph J, Rajkovic A. PMID: 32607512.
      View in: PubMed   Mentions:
    2. Testis formation in XX individuals resulting from novel pathogenic variants in Wilms' tumor 1 (WT1) gene. Proc Natl Acad Sci U S A. 2020 Jun 03. Eozenou C, Gonen N, Touzon MS, Jorgensen A, Yatsenko SA, Fusee L, Kamel AK, Gellen B, Guercio G, Singh P, Witchel S, Berman AJ, Mainpal R, Totonchi M, Mohseni Meybodi A, Askari M, Merel-Chali T, Bignon-Topalovic J, Migale R, Costanzo M, Marino R, Ramirez P, Perez Garrido N, Berensztein E, Mekkawy MK, Schimenti JC, Bertalan R, Mazen I, McElreavey K, Belgorosky A, Lovell-Badge R, Rajkovic A, Bashamboo A. PMID: 32493750.
      View in: PubMed   Mentions:    Fields:    
    3. Loss of Cx43 in Murine Sertoli Cells Leads to Altered Prepubertal Sertoli Cell Maturation and Impairment of the Mitosis-Meiosis Switch. Cells. 2020 Mar 10; 9(3). Hilbold E, Distl O, Hoedemaker M, Wilkening S, Behr R, Rajkovic A, Langeheine M, Rode K, Jung K, Metzger J, Brehm RHJ. PMID: 32164318.
      View in: PubMed   Mentions:    Fields:    
    4. Genetics of human female infertility†. Biol Reprod. 2019 09 01; 101(3):549-566. Yatsenko SA, Rajkovic A. PMID: 31077289.
      View in: PubMed   Mentions:    Fields:    
    5. A high-resolution X chromosome copy-number variation map in fertile females and women with primary ovarian insufficiency. Genet Med. 2019 10; 21(10):2275-2284. Yatsenko SA, Wood-Trageser M, Chu T, Jiang H, Rajkovic A. PMID: 30948856.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    6. Cell-Free DNA Screening During Pregnancy. JAMA. 2019 01 22; 321(3):308-309. Gregg AR, Rajkovic A. PMID: 30667496.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Gene variants identified by whole-exome sequencing in 33 French women with premature ovarian insufficiency. J Assist Reprod Genet. 2019 Jan; 36(1):39-45. Yang X, Touraine P, Desai S, Humphreys G, Jiang H, Yatsenko A, Rajkovic A. PMID: 30406445.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. X-linked ADGRG2 mutation and obstructive azoospermia in a large Pakistani family. Sci Rep. 2018 11 02; 8(1):16280. Khan MJ, Pollock N, Jiang H, Castro C, Nazli R, Ahmed J, Basit S, Rajkovic A, Yatsenko AN. PMID: 30389958.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    9. Autism spectrum disorder in females with ARHGEF9 alterations and a random pattern of X chromosome inactivation. Eur J Med Genet. 2019 Apr; 62(4):239-242. Aarabi M, Kessler E, Madan-Khetarpal S, Surti U, Bellissimo D, Rajkovic A, Yatsenko SA. PMID: 30048823.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    10. Mutations involving the SRY-related gene SOX8 are associated with a spectrum of human reproductive anomalies. Hum Mol Genet. 2018 04 01; 27(7):1228-1240. Portnoi MF, Dumargne MC, Rojo S, Witchel SF, Duncan AJ, Eozenou C, Bignon-Topalovic J, Yatsenko SA, Rajkovic A, Reyes-Mugica M, Almstrup K, Fusee L, Srivastava Y, Chantot-Bastaraud S, Hyon C, Louis-Sylvestre C, Validire P, de Malleray Pichard C, Ravel C, Christin-Maitre S, Brauner R, Rossetti R, Persani L, Charreau EH, Dain L, Chiauzzi VA, Mazen I, Rouba H, Schluth-Bolard C, MacGowan S, McLean WHI, Patin E, Rajpert-De Meyts E, Jauch R, Achermann JC, Siffroi JP, McElreavey K, Bashamboo A. PMID: 29373757.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCTClinical Trials
    11. Chromosomal instability in women with primary ovarian insufficiency. Hum Reprod. 2018 03 01; 33(3):531-538. Katari S, Aarabi M, Kintigh A, Mann S, Yatsenko SA, Sanfilippo JS, Zeleznik AJ, Rajkovic A. PMID: 29425284.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Synchronous Bilateral Tubal Serous Carcinomas in a Patient With Exon 13 Duplication and Loss of Function of BRCA1. Int J Gynecol Pathol. 2018 Mar; 37(2):117-122. Gurda GT, Serdy KM, Yatsenko SA, Rajkovic A, Carter NJ, Ahmed R, Olawaiye AB, Bhargava R, Elishaev E. PMID: 28463906.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    13. Importance of complete phenotyping in prenatal whole exome sequencing. Hum Genet. 2018 Feb; 137(2):175-181. Aarabi M, Sniezek O, Jiang H, Saller DN, Bellissimo D, Yatsenko SA, Rajkovic A. PMID: 29392406.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    14. Ovarian Follicular Theca Cell Recruitment, Differentiation, and Impact on Fertility: 2017 Update. Endocr Rev. 2018 02 01; 39(1):1-20. Richards JS, Ren YA, Candelaria N, Adams JE, Rajkovic A. PMID: 29028960.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    15. Functional study of a novel missense single-nucleotide variant of NUP107 in two daughters of Mexican origin with premature ovarian insufficiency. Mol Genet Genomic Med. 2018 03; 6(2):276-281. Ren Y, Diao F, Katari S, Yatsenko S, Jiang H, Wood-Trageser MA, Rajkovic A. PMID: 29363275.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    16. Beyond Down syndrome phenotype: Paternally derived isodicentric chromosome 21 with partial monosomy 21q22.3. Am J Med Genet A. 2017 Dec; 173(12):3153-3157. Putra M, Surti U, Hu J, Steele D, Clemens M, Saller DN, Yatsenko SA, Rajkovic A. PMID: 29048729.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    17. Ovary as a Biomarker of Health and Longevity: Insights from Genetics. Semin Reprod Med. 2017 05; 35(3):231-240. Rajkovic A, Pangas S. PMID: 28658706.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    18. Transcription factors SOHLH1 and SOHLH2 coordinate oocyte differentiation without affecting meiosis I. J Clin Invest. 2017 Jun 01; 127(6):2106-2117. Shin YH, Ren Y, Suzuki H, Golnoski KJ, Ahn HW, Mico V, Rajkovic A. PMID: 28504655.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    19. Female-to-male sex reversal associated with unique Xp21.2 deletion disrupting genomic regulatory architecture of the dosage-sensitive sex reversal region. J Med Genet. 2017 10; 54(10):705-709. Dangle P, Touzon MS, Reyes-Múgica M, Witchel SF, Rajkovic A, Schneck FX, Yatsenko SA. PMID: 28483799.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    20. Genetics of Reproductive Aging from Gonadal Dysgenesis through Menopause. Semin Reprod Med. 2017 03; 35(2):147-159. Desai S, Rajkovic A. PMID: 28278532.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    21. MCM8 and MCM9 Nucleotide Variants in Women With Primary Ovarian Insufficiency. J Clin Endocrinol Metab. 2017 02 01; 102(2):576-582. Desai S, Wood-Trageser M, Matic J, Chipkin J, Jiang H, Bachelot A, Dulon J, Sala C, Barbieri C, Cocca M, Toniolo D, Touraine P, Witchel S, Rajkovic A. PMID: 27802094.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    22. Med12 regulates ovarian steroidogenesis, uterine development and maternal effects in the mammalian egg. Biol Reprod. 2017 01 01; 97(6):822-834. Wang X, Mittal P, Castro CA, Rajkovic G, Rajkovic A. PMID: 29126187.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    23. Highly heterogeneous genomic landscape of uterine leiomyomas by whole exome sequencing and genome-wide arrays. Fertil Steril. 2017 02; 107(2):457-466.e9. Yatsenko SA, Mittal P, Wood-Trageser MA, Jones MW, Surti U, Edwards RP, Sood AK, Rajkovic A. PMID: 27889101.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    24. A design thinking approach to primary ovarian insufficiency. Panminerva Med. 2017 Mar; 59(1):15-32. Martin LA, Porter AG, Pelligrini VA, Schnatz PF, Jiang X, Kleinstreuer N, Hall JE, Verbiest S, Olmstead J, Fair R, Falorni A, Persani L, Rajkovic A, Mehta K, Nelson LM. PMID: 27827529.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    25. Subpallial Enhancer Transgenic Lines: a Data and Tool Resource to Study Transcriptional Regulation of GABAergic Cell Fate. Neuron. 2016 Oct 05; 92(1):59-74. Silberberg SN, Taher L, Lindtner S, Sandberg M, Nord AS, Vogt D, Mckinsey GL, Hoch R, Pattabiraman K, Zhang D, Ferran JL, Rajkovic A, Golonzhka O, Kim C, Zeng H, Puelles L, Visel A, Rubenstein JLR. PMID: 27710791.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    26. Familial deletion of the HOXA gene cluster associated with Hand-Foot-Genital syndrome and phenotypic variability. Am J Med Genet A. 2017 Jan; 173(1):221-224. Tas E, Sebastian J, Madan-Khetarpal S, Sweet P, Yatsenko AN, Pollock N, Rajkovic A, Schneck FX, Yatsenko SA, Witchel SF. PMID: 27649277.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    27. TAF4b Regulates Oocyte-Specific Genes Essential for Meiosis. PLoS Genet. 2016 06; 12(6):e1006128. Grive KJ, Gustafson EA, Seymour KA, Baddoo M, Schorl C, Golnoski K, Rajkovic A, Brodsky AS, Freiman RN. PMID: 27341508.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    28. Genotype-phenotype correlation and pregnancy outcomes of partial trisomy 14q: A systematic review. Am J Med Genet A. 2016 09; 170(9):2365-71. Bregand-White J, Saller DN, Clemens M, Surti U, Yatsenko SA, Rajkovic A. PMID: 27286879.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    29. Expansion of phenotype and genotypic data in CRB2-related syndrome. Eur J Hum Genet. 2016 10; 24(10):1436-44. Lamont RE, Tan WH, Innes AM, Parboosingh JS, Schneidman-Duhovny D, Rajkovic A, Pappas J, Altschwager P, DeWard S, Fulton A, Gray KJ, Krall M, Mehta L, Rodan LH, Saller DN, Steele D, Stein D, Yatsenko SA, Bernier FP, Slavotinek AM. PMID: 27004616.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    30. Response to Sahoo et al. Genet Med. 2016 Mar; 18(3):277. Yatsenko SA, Peters DG, Rajkovic A. PMID: 26795591.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    31. Integration of microarray analysis into the clinical diagnosis of hematological malignancies: How much can we improve cytogenetic testing? Oncotarget. 2015 Aug 07; 6(22):18845-62. Peterson JF, Aggarwal N, Smith CA, Gollin SM, Surti U, Rajkovic A, Swerdlow SH, Yatsenko SA. PMID: 26299921.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    32. Med12 gain-of-function mutation causes leiomyomas and genomic instability. J Clin Invest. 2015 Aug 03; 125(8):3280-4. Mittal P, Shin YH, Yatsenko SA, Castro CA, Surti U, Rajkovic A. PMID: 26193636.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimals
    33. Prenatal whole-exome sequencing: parental attitudes. Prenat Diagn. 2015 Oct; 35(10):1030-6. Kalynchuk EJ, Althouse A, Parker LS, Saller DN, Rajkovic A. PMID: 26151551.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    34. Reproductive aging and MCM8/9. Oncotarget. 2015 Jun 30; 6(18):15750-1. Yatsenko SA, Rajkovic A. PMID: 26119146.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    35. Lhx8 regulates primordial follicle activation and postnatal folliculogenesis. BMC Biol. 2015 Jun 16; 13:39. Ren Y, Suzuki H, Jagarlamudi K, Golnoski K, McGuire M, Lopes R, Pachnis V, Rajkovic A. PMID: 26076587.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    36. X-linked TEX11 mutations, meiotic arrest, and azoospermia in infertile men. N Engl J Med. 2015 May 28; 372(22):2097-107. Yatsenko AN, Georgiadis AP, Röpke A, Berman AJ, Jaffe T, Olszewska M, Westernströer B, Sanfilippo J, Kurpisz M, Rajkovic A, Yatsenko SA, Kliesch S, Schlatt S, Tüttelmann F. PMID: 25970010.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    37. Craniofacial abnormalities and developmental delay in two families with overlapping 22q12.1 microdeletions involving the MN1 gene. Am J Med Genet A. 2015 May; 167A(5):1047-53. Beck M, Peterson JF, McConnell J, McGuire M, Asato M, Losee JE, Surti U, Madan-Khetarpal S, Rajkovic A, Yatsenko SA. PMID: 25810350.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    38. Cell-free nucleic acids as non-invasive biomarkers of gynecological disorders, fetal aneuploidy and constitutional maternal chromosomal mosaicism. Hum Reprod Update. 2015 Sep-Oct; 21(5):690-2. Chu T, Yeniterzi S, Yatsenko SA, Dunkel M, Rajkovic A, Hogge WA, Peters DG. PMID: 25765864.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    39. Maternal cell-free DNA-based screening for fetal microdeletion and the importance of careful diagnostic follow-up. Genet Med. 2015 Oct; 17(10):836-8. Yatsenko SA, Peters DG, Saller DN, Chu T, Clemens M, Rajkovic A. PMID: 25569438.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    40. MCM9 mutations are associated with ovarian failure, short stature, and chromosomal instability. Am J Hum Genet. 2014 Dec 04; 95(6):754-62. Wood-Trageser MA, Gurbuz F, Yatsenko SA, Jeffries EP, Kotan LD, Surti U, Ketterer DM, Matic J, Chipkin J, Jiang H, Trakselis MA, Topaloglu AK, Rajkovic A. PMID: 25480036.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    41. Exome sequencing reveals MCM8 mutation underlies ovarian failure and chromosomal instability. J Clin Invest. 2015 Jan; 125(1):258-62. AlAsiri S, Basit S, Wood-Trageser MA, Yatsenko SA, Jeffries EP, Surti U, Ketterer DM, Afzal S, Ramzan K, Faiyaz-Ul Haque M, Jiang H, Trakselis MA, Rajkovic A. PMID: 25437880.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    42. Recent advances of genomic testing in perinatal medicine. Semin Perinatol. 2015 Feb; 39(1):44-54. Peters DG, Yatsenko SA, Surti U, Rajkovic A. PMID: 25444417.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    43. Prenatal diagnosis of trisomy 6q25.3-qter and monosomy 10q26.12-qter by array CGH in a fetus with an apparently normal karyotype. Clin Case Rep. 2015 Feb; 3(2):92-5. Marinescu PS, Saller DN, Parks WT, Yatsenko SA, Rajkovic A. PMID: 25767704.
      View in: PubMed   Mentions:
    44. High quality RNA in semen and sperm: isolation, analysis and potential application in clinical testing. J Urol. 2015 Jan; 193(1):352-9. Georgiadis AP, Kishore A, Zorrilla M, Jaffe TM, Sanfilippo JS, Volk E, Rajkovic A, Yatsenko AN. PMID: 25088949.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    45. Interstitial 10p11.23-p12.1 microdeletions associated with developmental delay, craniofacial abnormalities, and cryptorchidism. Am J Med Genet A. 2014 Oct; 164A(10):2623-6. Mroczkowski HJ, Arnold G, Schneck FX, Rajkovic A, Yatsenko SA. PMID: 25073539.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    46. Novel Mutation in the PKHD1 Gene Diagnosed Prenatally in a Fetus with Autosomal Recessive Polycystic Kidney Disease. Case Rep Genet. 2014; 2014:517952. Thakur P, Speer P, Rajkovic A. PMID: 25114813.
      View in: PubMed   Mentions:
    47. The transition from stem cell to progenitor spermatogonia and male fertility requires the SHP2 protein tyrosine phosphatase. Stem Cells. 2014 Mar; 32(3):741-53. Puri P, Phillips BT, Suzuki H, Orwig KE, Rajkovic A, Lapinski PE, King PD, Feng GS, Walker WH. PMID: 24123360.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    48. High resolution non-invasive detection of a fetal microdeletion using the GCREM algorithm. Prenat Diagn. 2014 May; 34(5):469-77. Chu T, Yeniterzi S, Rajkovic A, Hogge WA, Dunkel M, Shaw P, Bunce K, Peters DG. PMID: 24452987.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    49. Meta-analysis of loci associated with age at natural menopause in African-American women. Hum Mol Genet. 2014 Jun 15; 23(12):3327-42. Chen CT, Liu CT, Chen GK, Andrews JS, Arnold AM, Dreyfus J, Franceschini N, Garcia ME, Kerr KF, Li G, Lohman KK, Musani SK, Nalls MA, Raffel LJ, Smith J, Ambrosone CB, Bandera EV, Bernstein L, Britton A, Brzyski RG, Cappola A, Carlson CS, Couper D, Deming SL, Goodarzi MO, Heiss G, John EM, Lu X, Le Marchand L, Marciante K, Mcknight B, Millikan R, Nock NL, Olshan AF, Press MF, Vaiyda D, Woods NF, Taylor HA, Zhao W, Zheng W, Evans MK, Harris TB, Henderson BE, Kardia SL, Kooperberg C, Liu Y, Mosley TH, Psaty B, Wellons M, Windham BG, Zonderman AB, Cupples LA, Demerath EW, Haiman C, Murabito JM, Rajkovic A. PMID: 24493794.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    50. Familial microduplication of 17q23.1–q23.2 involving TBX4 is associated with congenital clubfoot and reduced penetrance in females. Am J Med Genet A. 2014 Feb; 164A(2):364-9. Peterson JF, Ghaloul-Gonzalez L, Madan-Khetarpal S, Hartman J, Surti U, Rajkovic A, Yatsenko SA. PMID: 24592505.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    51. Spermatogonial SOHLH1 nucleocytoplasmic shuttling associates with initiation of spermatogenesis in the rhesus monkey (Macaca mulatta). Mol Hum Reprod. 2014 Apr; 20(4):350-7. Ramaswamy S, Razack BS, Roslund RM, Suzuki H, Marshall GR, Rajkovic A, Plant TM. PMID: 24324034.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    52. Genomic markers of ovarian reserve. Semin Reprod Med. 2013 Nov; 31(6):399-415. Wood MA, Rajkovic A. PMID: 24101221.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimals
    53. Mouse HORMAD1 is a meiosis i checkpoint protein that modulates DNA double- strand break repair during female meiosis. Biol Reprod. 2013 Aug; 89(2):29. Shin YH, McGuire MM, Rajkovic A. PMID: 23759310.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    54. Genome-wide association study of age at menarche in African-American women. Hum Mol Genet. 2013 Aug 15; 22(16):3329-46. Demerath EW, Liu CT, Franceschini N, Chen G, Palmer JR, Smith EN, Chen CT, Ambrosone CB, Arnold AM, Bandera EV, Berenson GS, Bernstein L, Britton A, Cappola AR, Carlson CS, Chanock SJ, Chen W, Chen Z, Deming SL, Elks CE, Evans MK, Gajdos Z, Henderson BE, Hu JJ, Ingles S, John EM, Kerr KF, Kolonel LN, Le Marchand L, Lu X, Millikan RC, Musani SK, Nock NL, North K, Nyante S, Press MF, Rodriquez-Gil JL, Ruiz-Narvaez EA, Schork NJ, Srinivasan SR, Woods NF, Zheng W, Ziegler RG, Zonderman A, Heiss G, Gwen Windham B, Wellons M, Murray SS, Nalls M, Pastinen T, Rajkovic A, Hirschhorn J, Adrienne Cupples L, Kooperberg C, Murabito JM, Haiman CA. PMID: 23599027.
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    55. Granulocyte colony-stimulating factor with or without stem cell factor extends time to premature ovarian insufficiency in female mice treated with alkylating chemotherapy. Fertil Steril. 2013 Jun; 99(7):2045-54.e3. Skaznik-Wikiel ME, McGuire MM, Sukhwani M, Donohue J, Chu T, Krivak TC, Rajkovic A, Orwig KE. PMID: 23453120.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    56. Genetic variation and reproductive timing: African American women from the Population Architecture using Genomics and Epidemiology (PAGE) Study. PLoS One. 2013; 8(2):e55258. Spencer KL, Malinowski J, Carty CL, Franceschini N, Fernández-Rhodes L, Young A, Cheng I, Ritchie MD, Haiman CA, Wilkens L, Matise TC, Carlson CS, Brennan K, Park A, Rajkovic A, Hindorff LA, Buyske S, Crawford DC. PMID: 23424626.
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    57. A systematic mapping approach of 16q12.2/FTO and BMI in more than 20,000 African Americans narrows in on the underlying functional variation: results from the Population Architecture using Genomics and Epidemiology (PAGE) study. PLoS Genet. 2013; 9(1):e1003171. Peters U, North KE, Sethupathy P, Buyske S, Haessler J, Jiao S, Fesinmeyer MD, Jackson RD, Kuller LH, Rajkovic A, Lim U, Cheng I, Schumacher F, Wilkens L, Li R, Monda K, Ehret G, Nguyen KD, Cooper R, Lewis CE, Leppert M, Irvin MR, Gu CC, Houston D, Buzkova P, Ritchie M, Matise TC, Le Marchand L, Hindorff LA, Crawford DC, Haiman CA, Kooperberg C. PMID: 23341774.
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    58. Generation of a germ cell-specific mouse transgenic CHERRY reporter, Sohlh1-mCherryFlag. Genesis. 2013 Jan; 51(1):50-8. Suzuki H, Dann CT, Rajkovic A. PMID: 22965810.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    59. Biological significance of HORMA domain containing protein 1 (HORMAD1) in epithelial ovarian carcinoma. Cancer Lett. 2013 Apr 28; 330(2):123-9. Shahzad MM, Shin YH, Matsuo K, Lu C, Nishimura M, Shen DY, Kang Y, Hu W, Mora EM, Rodriguez-Aguayo C, Kapur A, Bottsford-Miller J, Lopez-Berestein G, Rajkovic A, Sood AK. PMID: 22776561.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    60. Prenatal diagnosis of 2q32 deletion syndrome characterized by multiple segmental deletions and complex chromosomal rearrangement involving chromosomes 2, 5 and 7. Fetal Diagn Ther. 2012; 31(3):196-200. Thorson HL, Surti U, Sathanoori M, Kochmar SJ, Torchia B, Rajkovic A. PMID: 22415219.
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    61. Whole exome sequencing in a random sample of North American women with leiomyomas identifies MED12 mutations in majority of uterine leiomyomas. PLoS One. 2012; 7(3):e33251. McGuire MM, Yatsenko A, Hoffner L, Jones M, Surti U, Rajkovic A. PMID: 22428002.
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    62. Prenatally diagnosed 17q12 microdeletion syndrome with a novel association with congenital diaphragmatic hernia. Fetal Diagn Ther. 2012; 31(2):129-33. Hendrix NW, Clemens M, Canavan TP, Surti U, Rajkovic A. PMID: 22178801.
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    63. Replication of loci influencing ages at menarche and menopause in Hispanic women: the Women's Health Initiative SHARe Study. Hum Mol Genet. 2012 Mar 15; 21(6):1419-32. Chen CT, Fernández-Rhodes L, Brzyski RG, Carlson CS, Chen Z, Heiss G, North KE, Woods NF, Rajkovic A, Kooperberg C, Franceschini N. PMID: 22131368.
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    64. Noninvasive prenatal diagnosis of a fetal microdeletion syndrome. N Engl J Med. 2011 Nov 10; 365(19):1847-8. Peters D, Chu T, Yatsenko SA, Hendrix N, Hogge WA, Surti U, Bunce K, Dunkel M, Shaw P, Rajkovic A. PMID: 22070496.
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    65. SOHLH1 and SOHLH2 coordinate spermatogonial differentiation. Dev Biol. 2012 Jan 15; 361(2):301-12. Suzuki H, Ahn HW, Chu T, Bowden W, Gassei K, Orwig K, Rajkovic A. PMID: 22056784.
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    66. Oogenesis: transcriptional regulators and mouse models. Mol Cell Endocrinol. 2012 Jun 05; 356(1-2):31-9. Jagarlamudi K, Rajkovic A. PMID: 21856374.
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    67. Complex X chromosome rearrangement delineated by array comparative genome hybridization in a woman with premature ovarian insufficiency. Fertil Steril. 2011 Jun; 95(7):2433.e9-15. Ochalski ME, Engle N, Wakim A, Ravnan BJ, Hoffner L, Rajkovic A, Surti U. PMID: 21530964.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    68. Premature ovarian failure in nobox-deficient mice is caused by defects in somatic cell invasion and germ cell cyst breakdown. J Assist Reprod Genet. 2011 Jul; 28(7):583-9. Lechowska A, Bilinski S, Choi Y, Shin Y, Kloc M, Rajkovic A. PMID: 21369782.
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    69. Genomic analysis using high-resolution single-nucleotide polymorphism arrays reveals novel microdeletions associated with premature ovarian failure. Fertil Steril. 2011 Apr; 95(5):1595-600. McGuire MM, Bowden W, Engel NJ, Ahn HW, Kovanci E, Rajkovic A. PMID: 21256485.
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    70. Body size phenotypes and inflammation in the Women's Health Initiative Observational Study. Obesity (Silver Spring). 2011 Jul; 19(7):1482-91. Wildman RP, Kaplan R, Manson JE, Rajkovic A, Connelly SA, Mackey RH, Tinker LF, Curb JD, Eaton CB, Wassertheil-Smoller S. PMID: 21233809.
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    71. Characterization of the association between 8q24 and colon cancer: gene-environment exploration and meta-analysis. BMC Cancer. 2010 Dec 04; 10:670. Hutter CM, Slattery ML, Duggan DJ, Muehling J, Curtin K, Hsu L, Beresford SA, Rajkovic A, Sarto GE, Marshall JR, Hammad N, Wallace R, Makar KW, Prentice RL, Caan BJ, Potter JD, Peters U. PMID: 21129217.
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    72. Hormad1 mutation disrupts synaptonemal complex formation, recombination, and chromosome segregation in mammalian meiosis. PLoS Genet. 2010 Nov 04; 6(11):e1001190. Shin YH, Choi Y, Erdin SU, Yatsenko SA, Kloc M, Yang F, Wang PJ, Meistrich ML, Rajkovic A. PMID: 21079677.
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    73. Characterization of 9p24 risk locus and colorectal adenoma and cancer: gene-environment interaction and meta-analysis. Cancer Epidemiol Biomarkers Prev. 2010 Dec; 19(12):3131-9. Kocarnik JD, Hutter CM, Slattery ML, Berndt SI, Hsu L, Duggan DJ, Muehling J, Caan BJ, Beresford SA, Rajkovic A, Sarto GE, Marshall JR, Hammad N, Wallace RB, Makar KW, Prentice RL, Potter JD, Hayes RB, Peters U. PMID: 20978172.
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    74. Estrogen plus progestin and breast cancer incidence and mortality in postmenopausal women. JAMA. 2010 Oct 20; 304(15):1684-92. Chlebowski RT, Anderson GL, Gass M, Lane DS, Aragaki AK, Kuller LH, Manson JE, Stefanick ML, Ockene J, Sarto GE, Johnson KC, Wactawski-Wende J, Ravdin PM, Schenken R, Hendrix SL, Rajkovic A, Rohan TE, Yasmeen S, Prentice RL. PMID: 20959578.
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    75. Family history of cancer and risk of pancreatic cancer: a pooled analysis from the Pancreatic Cancer Cohort Consortium (PanScan). Int J Cancer. 2010 Sep 01; 127(6):1421-8. Jacobs EJ, Chanock SJ, Fuchs CS, Lacroix A, McWilliams RR, Steplowski E, Stolzenberg-Solomon RZ, Arslan AA, Bueno-de-Mesquita HB, Gross M, Helzlsouer K, Petersen G, Zheng W, Agalliu I, Allen NE, Amundadottir L, Boutron-Ruault MC, Buring JE, Canzian F, Clipp S, Dorronsoro M, Gaziano JM, Giovannucci EL, Hankinson SE, Hartge P, Hoover RN, Hunter DJ, Jacobs KB, Jenab M, Kraft P, Kooperberg C, Lynch SM, Sund M, Mendelsohn JB, Mouw T, Newton CC, Overvad K, Palli D, Peeters PH, Rajkovic A, Shu XO, Thomas G, Tobias GS, Trichopoulos D, Virtamo J, Wactawski-Wende J, Wolpin BM, Yu K, Zeleniuch-Jacquotte A. PMID: 20049842.
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    76. The oocyte-specific transcription factor, Nobox, regulates the expression of Pad6, a peptidylarginine deiminase in the oocyte. FEBS Lett. 2010 Aug 20; 584(16):3629-34. Choi M, Lee OH, Jeon S, Park M, Lee DR, Ko JJ, Yoon TK, Rajkovic A, Choi Y. PMID: 20659469.
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    77. Mutations in SOHLH1 gene associate with nonobstructive azoospermia. Hum Mutat. 2010 Jul; 31(7):788-93. Choi Y, Jeon S, Choi M, Lee MH, Park M, Lee DR, Jun KY, Kwon Y, Lee OH, Song SH, Kim JY, Lee KA, Yoon TK, Rajkovic A, Shim SH. PMID: 20506135.
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    78. The effects of postmenopausal hormone therapy on serum estrogen, progesterone, and sex hormone-binding globulin levels in healthy postmenopausal women. Menopause. 2010 May-Jun; 17(3):622-9. Edlefsen KL, Jackson RD, Prentice RL, Janssen I, Rajkovic A, O'Sullivan MJ, Anderson G. PMID: 20215977.
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    79. MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing. Mol Hum Reprod. 2010 Jul; 16(7):463-71. Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A. PMID: 20215419.
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    80. Low-fat dietary pattern and lipoprotein risk factors: the Women's Health Initiative Dietary Modification Trial. Am J Clin Nutr. 2010 Apr; 91(4):860-74. Howard BV, Curb JD, Eaton CB, Kooperberg C, Ockene J, Kostis JB, Pettinger M, Rajkovic A, Robinson JG, Rossouw J, Sarto G, Shikany JM, Van Horn L. PMID: 20164311.
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    81. Pancreatic cancer risk and ABO blood group alleles: results from the pancreatic cancer cohort consortium. Cancer Res. 2010 Feb 01; 70(3):1015-23. Wolpin BM, Kraft P, Gross M, Helzlsouer K, Bueno-de-Mesquita HB, Steplowski E, Stolzenberg-Solomon RZ, Arslan AA, Jacobs EJ, Lacroix A, Petersen G, Zheng W, Albanes D, Allen NE, Amundadottir L, Anderson G, Boutron-Ruault MC, Buring JE, Canzian F, Chanock SJ, Clipp S, Gaziano JM, Giovannucci EL, Hallmans G, Hankinson SE, Hoover RN, Hunter DJ, Hutchinson A, Jacobs K, Kooperberg C, Lynch SM, Mendelsohn JB, Michaud DS, Overvad K, Patel AV, Rajkovic A, Sanchéz MJ, Shu XO, Slimani N, Thomas G, Tobias GS, Trichopoulos D, Vineis P, Virtamo J, Wactawski-Wende J, Yu K, Zeleniuch-Jacquotte A, Hartge P, Fuchs CS. PMID: 20103627.
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    82. A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33. Nat Genet. 2010 Mar; 42(3):224-8. Petersen GM, Amundadottir L, Fuchs CS, Kraft P, Stolzenberg-Solomon RZ, Jacobs KB, Arslan AA, Bueno-de-Mesquita HB, Gallinger S, Gross M, Helzlsouer K, Holly EA, Jacobs EJ, Klein AP, LaCroix A, Li D, Mandelson MT, Olson SH, Risch HA, Zheng W, Albanes D, Bamlet WR, Berg CD, Boutron-Ruault MC, Buring JE, Bracci PM, Canzian F, Clipp S, Cotterchio M, de Andrade M, Duell EJ, Gaziano JM, Giovannucci EL, Goggins M, Hallmans G, Hankinson SE, Hassan M, Howard B, Hunter DJ, Hutchinson A, Jenab M, Kaaks R, Kooperberg C, Krogh V, Kurtz RC, Lynch SM, McWilliams RR, Mendelsohn JB, Michaud DS, Parikh H, Patel AV, Peeters PH, Rajkovic A, Riboli E, Rodriguez L, Seminara D, Shu XO, Thomas G, Tjønneland A, Tobias GS, Trichopoulos D, Van Den Eeden SK, Virtamo J, Wactawski-Wende J, Wang Z, Wolpin BM, Yu H, Yu K, Zeleniuch-Jacquotte A, Fraumeni JF, Hoover RN, Hartge P, Chanock SJ. PMID: 20101243.
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    83. Vasomotor symptoms, adoption of a low-fat dietary pattern, and risk of invasive breast cancer: a secondary analysis of the Women's Health Initiative randomized controlled dietary modification trial. J Clin Oncol. 2009 Sep 20; 27(27):4500-7. Caan BJ, Aragaki A, Thomson CA, Stefanick ML, Chlebowski R, Hubbell FA, Tinker L, Vitolins M, Rajkovic A, Bueche M, Ockene J. PMID: 19687338.
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    84. Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer. Nat Genet. 2009 Sep; 41(9):986-90. Amundadottir L, Kraft P, Stolzenberg-Solomon RZ, Fuchs CS, Petersen GM, Arslan AA, Bueno-de-Mesquita HB, Gross M, Helzlsouer K, Jacobs EJ, LaCroix A, Zheng W, Albanes D, Bamlet W, Berg CD, Berrino F, Bingham S, Buring JE, Bracci PM, Canzian F, Clavel-Chapelon F, Clipp S, Cotterchio M, de Andrade M, Duell EJ, Fox JW, Gallinger S, Gaziano JM, Giovannucci EL, Goggins M, González CA, Hallmans G, Hankinson SE, Hassan M, Holly EA, Hunter DJ, Hutchinson A, Jackson R, Jacobs KB, Jenab M, Kaaks R, Klein AP, Kooperberg C, Kurtz RC, Li D, Lynch SM, Mandelson M, McWilliams RR, Mendelsohn JB, Michaud DS, Olson SH, Overvad K, Patel AV, Peeters PH, Rajkovic A, Riboli E, Risch HA, Shu XO, Thomas G, Tobias GS, Trichopoulos D, Van Den Eeden SK, Virtamo J, Wactawski-Wende J, Wolpin BM, Yu H, Yu K, Zeleniuch-Jacquotte A, Chanock SJ, Hartge P, Hoover RN. PMID: 19648918.
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    85. Detection of novel copy number variants in uterine leiomyomas using high-resolution SNP arrays. Mol Hum Reprod. 2009 Sep; 15(9):563-8. Bowden W, Skorupski J, Kovanci E, Rajkovic A. PMID: 19567454.
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    86. Relaxin signaling in uterine fibroids. Ann N Y Acad Sci. 2009 Apr; 1160:374-8. Li Z, Burzawa JK, Troung A, Feng S, Agoulnik IU, Tong X, Anderson ML, Kovanci E, Rajkovic A, Agoulnik AI. PMID: 19416222.
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    87. Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2. Nat Genet. 2009 May; 41(5):585-90. Ahmed S, Thomas G, Ghoussaini M, Healey CS, Humphreys MK, Platte R, Morrison J, Maranian M, Pooley KA, Luben R, Eccles D, Evans DG, Fletcher O, Johnson N, dos Santos Silva I, Peto J, Stratton MR, Rahman N, Jacobs K, Prentice R, Anderson GL, Rajkovic A, Curb JD, Ziegler RG, Berg CD, Buys SS, McCarty CA, Feigelson HS, Calle EE, Thun MJ, Diver WR, Bojesen S, Nordestgaard BG, Flyger H, Dörk T, Schürmann P, Hillemanns P, Karstens JH, Bogdanova NV, Antonenkova NN, Zalutsky IV, Bermisheva M, Fedorova S, Khusnutdinova E, Kang D, Yoo KY, Noh DY, Ahn SH, Devilee P, van Asperen CJ, Tollenaar RA, Seynaeve C, Garcia-Closas M, Lissowska J, Brinton L, Peplonska B, Nevanlinna H, Heikkinen T, Aittomäki K, Blomqvist C, Hopper JL, Southey MC, Smith L, Spurdle AB, Schmidt MK, Broeks A, van Hien RR, Cornelissen S, Milne RL, Ribas G, González-Neira A, Benitez J, Schmutzler RK, Burwinkel B, Bartram CR, Meindl A, Brauch H, Justenhoven C, Hamann U, Chang-Claude J, Hein R, Wang-Gohrke S, Lindblom A, Margolin S, Mannermaa A, Kosma VM, Kataja V, Olson JE, Wang X, Fredericksen Z, Giles GG, Severi G, Baglietto L, English DR, Hankinson SE, Cox DG, Kraft P, Vatten LJ, Hveem K, Kumle M, Sigurdson A, Doody M, Bhatti P, Alexander BH, Hooning MJ, van den Ouweland AM, Oldenburg RA, Schutte M, Hall P, Czene K, Liu J, Li Y, Cox A, Elliott G, Brock I, Reed MW, Shen CY, Yu JC, Hsu GC, Chen ST, Anton-Culver H, Ziogas A, Andrulis IL, Knight JA, Beesley J, Goode EL, Couch F, Chenevix-Trench G, Hoover RN, Ponder BA, Hunter DJ, Pharoah PD, Dunning AM, Chanock SJ, Easton DF. PMID: 19330027.
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    88. Breast cancer after use of estrogen plus progestin in postmenopausal women. N Engl J Med. 2009 Feb 05; 360(6):573-87. Chlebowski RT, Kuller LH, Prentice RL, Stefanick ML, Manson JE, Gass M, Aragaki AK, Ockene JK, Lane DS, Sarto GE, Rajkovic A, Schenken R, Hendrix SL, Ravdin PM, Rohan TE, Yasmeen S, Anderson G. PMID: 19196674.
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    89. MicroRNAs and mammalian ovarian development. Semin Reprod Med. 2008 Nov; 26(6):461-8. Zhao H, Rajkovic A. PMID: 18951328.
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    90. Germ cell-specific transcriptional regulator sohlh2 is essential for early mouse folliculogenesis and oocyte-specific gene expression. Biol Reprod. 2008 Dec; 79(6):1176-82. Choi Y, Yuan D, Rajkovic A. PMID: 18753606.
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    91. Expression and localization of the novel and highly conserved gametocyte-specific factor 1 during oogenesis and spermatogenesis. Fertil Steril. 2009 May; 91(5 Suppl):2020-4. Krotz SP, Ballow DJ, Choi Y, Rajkovic A. PMID: 18706558.
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    92. Lim homeobox gene, lhx8, is essential for mouse oocyte differentiation and survival. Biol Reprod. 2008 Sep; 79(3):442-9. Choi Y, Ballow DJ, Xin Y, Rajkovic A. PMID: 18509161.
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    93. Transcription factor FIGLA is mutated in patients with premature ovarian failure. Am J Hum Genet. 2008 Jun; 82(6):1342-8. Zhao H, Chen ZJ, Qin Y, Shi Y, Wang S, Choi Y, Simpson JL, Rajkovic A. PMID: 18499083.
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    94. Placenta percreta at 7th week of pregnancy in a woman with previous caesarean section. J Obstet Gynaecol. 2008 Apr; 28(3):338-40. Tanyi JL, Coleman NM, Johnston ND, Ayensu-Coker L, Rajkovic A. PMID: 18569483.
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    95. NOBOX homeobox mutation causes premature ovarian failure. Am J Hum Genet. 2007 Sep; 81(3):576-81. Qin Y, Choi Y, Zhao H, Simpson JL, Chen ZJ, Rajkovic A. PMID: 17701902.
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    96. Analysis of LHX8 mutation in premature ovarian failure. Fertil Steril. 2008 Apr; 89(4):1012-4. Qin Y, Zhao H, Kovanci E, Simpson JL, Chen ZJ, Rajkovic A. PMID: 17624344.
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    97. Analysis of TATA-binding protein 2 (TBP2) and TBP expression suggests different roles for the two proteins in regulation of gene expression during oogenesis and early mouse development. Reproduction. 2007 Jul; 134(1):51-62. Gazdag E, Rajkovic A, Torres-Padilla ME, Tora L. PMID: 17641088.
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    98. Genetics of ovarian failure and development. Semin Reprod Med. 2007 Jul; 25(4):223-4. Rajkovic A. PMID: 17594602.
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    99. Microarray analyses of newborn mouse ovaries lacking Nobox. Biol Reprod. 2007 Aug; 77(2):312-9. Choi Y, Qin Y, Berger MF, Ballow DJ, Bulyk ML, Rajkovic A. PMID: 17494914.
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    100. Analyses of GDF9 mutation in 100 Chinese women with premature ovarian failure. Fertil Steril. 2007 Nov; 88(5):1474-6. Zhao H, Qin Y, Kovanci E, Simpson JL, Chen ZJ, Rajkovic A. PMID: 17482612.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    101. Mutation analysis of NANOS3 in 80 Chinese and 88 Caucasian women with premature ovarian failure. Fertil Steril. 2007 Nov; 88(5):1465-7. Qin Y, Zhao H, Kovanci E, Simpson JL, Chen ZJ, Rajkovic A. PMID: 17418157.
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    102. Candidate genes for premature ovarian failure. Curr Med Chem. 2007; 14(3):353-7. Suzumori N, Pangas SA, Rajkovic A. PMID: 17305537.
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    103. Characterization of NOBOX DNA binding specificity and its regulation of Gdf9 and Pou5f1 promoters. J Biol Chem. 2006 Nov 24; 281(47):35747-56. Choi Y, Rajkovic A. PMID: 16997917.
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    104. Oogenesis requires germ cell-specific transcriptional regulators Sohlh1 and Lhx8. Proc Natl Acad Sci U S A. 2006 May 23; 103(21):8090-5. Pangas SA, Choi Y, Ballow DJ, Zhao Y, Westphal H, Matzuk MM, Rajkovic A. PMID: 16690745.
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    105. Sohlh2 is a germ cell-specific bHLH transcription factor. Gene Expr Patterns. 2006 Oct; 6(8):1014-8. Ballow DJ, Xin Y, Choi Y, Pangas SA, Rajkovic A. PMID: 16765102.
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    106. TEX14 is essential for intercellular bridges and fertility in male mice. Proc Natl Acad Sci U S A. 2006 Mar 28; 103(13):4982-7. Greenbaum MP, Yan W, Wu MH, Lin YN, Agno JE, Sharma M, Braun RE, Rajkovic A, Matzuk MM. PMID: 16549803.
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    107. Transcriptional regulation of early oogenesis: in search of masters. Hum Reprod Update. 2006 Jan-Feb; 12(1):65-76. Pangas SA, Rajkovic A. PMID: 16143663.
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    108. Restricted germ cell expression of a gene encoding a novel mammalian HORMA domain-containing protein. Gene Expr Patterns. 2004 Dec; 5(2):257-63. Pangas SA, Yan W, Matzuk MM, Rajkovic A. PMID: 15567723.
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    109. NOBOX deficiency disrupts early folliculogenesis and oocyte-specific gene expression. Science. 2004 Aug 20; 305(5687):1157-9. Rajkovic A, Pangas SA, Ballow D, Suzumori N, Matzuk MM. PMID: 15326356.
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    110. Identification of expressed sequence tags preferentially expressed in human placentas by in silico subtraction. Prenat Diagn. 2003 May; 23(5):410-9. Miner D, Rajkovic A. PMID: 12749040.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    111. Sequence and expression of testis-expressed gene 14 (Tex14): a gene encoding a protein kinase preferentially expressed during spermatogenesis. Gene Expr Patterns. 2003 May; 3(2):231-6. Wu MH, Rajkovic A, Burns KH, Yan W, Lin YN, Matzuk MM. PMID: 12711554.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    112. Expression of Drosophila neoplastic tumor suppressor genes discslarge, scribble, and lethal giant larvae in the mammalian ovary. Gene Expr Patterns. 2003 Mar; 3(1):3-11. Huang JH, Rajkovic A, Szafranski P, Ochsner S, Richards J, Goode S. PMID: 12609595.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    113. Identification of Gasz, an evolutionarily conserved gene expressed exclusively in germ cells and encoding a protein with four ankyrin repeats, a sterile-alpha motif, and a basic leucine zipper. Mol Endocrinol. 2002 Jun; 16(6):1168-84. Yan W, Rajkovic A, Viveiros MM, Burns KH, Eppig JJ, Matzuk MM. PMID: 12040005.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    114. Obox, a family of homeobox genes preferentially expressed in germ cells. Genomics. 2002 May; 79(5):711-7. Rajkovic A, Yan C, Yan W, Klysik M, Matzuk MM. PMID: 11991721.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    115. The ret finger protein-like 4 gene, Rfpl4, encodes a putative E3 ubiquitin-protein ligase expressed in adult germ cells. Mech Dev. 2002 Mar; 112(1-2):173-7. Rajkovic A, Lee JH, Yan C, Matzuk MM. PMID: 11850190.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    116. Functional analysis of oocyte-expressed genes using transgenic models. Mol Cell Endocrinol. 2002 Feb 22; 187(1-2):5-9. Rajkovic A, Matzuk MM. PMID: 11988305.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    117. Nobox is a homeobox-encoding gene preferentially expressed in primordial and growing oocytes. Mech Dev. 2002 Feb; 111(1-2):137-41. Suzumori N, Yan C, Matzuk MM, Rajkovic A. PMID: 11804785.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
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