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Linda Giudice, MD, PhD

TitleProfessor
InstitutionUniversity of California San Francisco
DepartmentOb/Gyn, Reproductive Sciences
Address513 Parnassus Ave
San Francisco CA 94143
Phone415-502-2637
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    Other Positions
    TitleObstetrics, Gynecology and Reproductive Sciences


    Collapse Biography 
    Collapse Education and Training
    Stanford UniversityM.D.1982School of Medicine

    Collapse Overview 
    Collapse Overview
    Linda C. Giudice, MD, PhD is Distinguished Professor, Chair Emerita, and the Robert B. Jaffe MD Endowed Professor in the Reproductive Sciences in the Department of Obstetrics, Gynecology and Reproductive Sciences at the University of California, San Francisco (UCSF). She is a biochemist and reproductive endocrinologist specializing in endometriosis and infertility. Her research focuses on human endometrial function and regeneration, genetics and epigenetics of endometriosis, placental-uterine interactions relevant to pregnancy outcomes, and evaluating the evidence of environmental impacts on reproductive health and human development. She has mentored over 250 students, fellows and faculty, authored > 300 peer-reviewed publications, and is co-editor of 6 textbooks on women’s health, reproductive environmental health, endocrinology, endometrium and endometriosis. She is Past-President of the American Society for Reproductive Medicine, the Society for Gynecologic Investigation, President of the World Endometriosis Society, President-elect of the International Federation of Fertility Societies, and Chair of the FIGO (International Federation of Gynecology and Obstetrics) Reproductive and Developmental Environmental Health Working Group. Dr. Giudice is on the UCSF Steering Committee on Women’s Precision Medicine, the March of Dimes Scientific Advisory Council, and is an elected member of the U.S. National Academy of Medicine and the U.S. National Academy of Inventors.


    Collapse Research 
    Collapse Research Activities and Funding
    Integrative Analysis of Genomic, Epigenomic and Phenotypic Data for Disease Stratification of Endometriosis
    NIH/NICHD R01HD089511Sep 26, 2016 - Apr 30, 2021
    Role: Principal Investigator
    Exploring HIV-Host Interactions in the Female Reproductive Tract
    NIH/NIAID P01AI083050Sep 1, 2009 - Aug 31, 2014
    Role: Co-Principal Investigator
    Origins and Biological Consequences of Human Infertility
    NIH/NICHD U54HD055764May 3, 2007 - Mar 31, 2017
    Role: Principal Investigator
    Center for Research, Innovation and Training in Reproduction and Infertility
    NIH/NICHD P50HD055764Apr 1, 2007 - Mar 31, 2023
    Role: Principal Investigator
    Summit on Environmental Challenges to Reproductive Health and Fertility
    NIH/NIEHS R13ES015427Sep 15, 2006 - Aug 31, 2007
    Role: Principal Investigator
    Mentoring &Interdisciplinary Research in Women's Health
    NIH/NICHD K12HD043452Sep 27, 2002 - Dec 31, 2008
    Role: Co-Principal Investigator
    Gordon Research Conference on Reproductive Tract Biology
    NIH/NICHD R13HD042663Jun 19, 2002 - May 31, 2003
    Role: Principal Investigator
    Federally Registered Human Embryonic Stem Cell Center
    NIH/NCRR R24RR017498May 1, 2002 - Jul 31, 2007
    Role: Principal Investigator
    Role of IGF-II in Human Trophoblast-Decidua Interactions
    NIH/NICHD U01HD042298Apr 1, 2002 - Mar 31, 2008
    Role: Principal Investigator
    HYPOXIA, IGFBP-1, AND HUMAN FETAL GROWTH
    NIH/NICHD R01HD036732Mar 1, 2000 - Aug 31, 2004
    Role: Principal Investigator
    Women's Reproductive Health Research
    NIH/NICHD K12HD001262Sep 30, 1998 - Jun 30, 2020
    Role: Co-Principal Investigator
    Gonadal and Endometrial Function in Human Reproduction
    NIH/NICHD U54HD031398Apr 7, 1997 - Mar 31, 2008
    Role: Co-Principal Investigator
    ROLE OF IGF IN HUMAN OVARY
    NIH/NICHD R01HD031579May 1, 1994 - Sep 30, 2008
    Role: Principal Investigator
    INSULIN-LIKE GROWTH FACTOR SYSTEM IN OVIDUCT
    NIH/NICHD R03HD028079May 1, 1991 - Apr 30, 1993
    Role: Principal Investigator
    IGF BINDING PROTEINS AND HUMAN ENDOMETRIUM
    NIH/NICHD R01HD025220Apr 1, 1990 - Jul 31, 2002
    Role: Principal Investigator
    GENE EXPRESSION IN ENDOMETRIUM
    NIH/NICHD R29HD025220Apr 1, 1990 - Mar 31, 1996
    Role: Principal Investigator
    General Clinical Research Center
    NIH M01RR000070Dec 1, 1978 - Nov 30, 2011
    Role: Co-Investigator

    Collapse ORNG Applications 
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    Collapse In The News

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Niederberger C, Pellicer A, Cohen J, Gardner DK, Palermo GD, O'Neill CL, Chow S, Rosenwaks Z, Cobo A, Swain JE, Schoolcraft WB, Frydman R, Bishop LA, Aharon D, Gordon C, New E, Decherney A, Tan SL, Paulson RJ, Goldfarb JM, Brännström M, Donnez J, Silber S, Dolmans MM, Simpson JL, Handyside AH, Munné S, Eguizabal C, Montserrat N, Izpisua Belmonte JC, Trounson A, Simon C, Tulandi T, Giudice LC, Norman RJ, Hsueh AJ, Sun Y, Laufer N, Kochman R, Eldar-Geva T, Lunenfeld B, Ezcurra D, D'Hooghe T, Fauser BCJM, Tarlatzis BC, Meldrum DR, Casper RF, Fatemi HM, Devroey P, Galliano D, Wikland M, Sigman M, Schoor RA, Goldstein M, Lipshultz LI, Schlegel PN, Hussein A, Oates RD, Brannigan RE, Ross HE, Pennings G, Klock SC, Brown S, Van Steirteghem A, Rebar RW, LaBarbera AR. Forty years of IVF. Fertil Steril. 2018 Jul 15; 110(2):185-324.e5. PMID: 30053940.
      View in: PubMed
    2. Surrey E, Taylor HS, Giudice L, Lessey BA, Abrao MS, Archer DF, Diamond MP, Johnson NP, Watts NB, Gallagher JC, Simon JA, Carr BR, Dmowski WP, Leyland N, Singh SS, Rechberger T, Agarwal SK, Duan WR, Schwefel B, Thomas JW, Peloso PM, Ng J, Soliman AM, Chwalisz K. Long-Term Outcomes of Elagolix in Women With Endometriosis: Results From Two Extension Studies. Obstet Gynecol. 2018 Jun 06. PMID: 29889764.
      View in: PubMed
    3. Barnhart K, Giudice L, Young S, Thomas T, Diamond MP, Segars J, Youssef WA, Krawetz S, Santoro N, Eisenberg E, Zhang H. Evaluation, validation and refinement of noninvasive diagnostic biomarkers for endometriosis (ENDOmarker): A protocol to phenotype bio-specimens for discovery and validation. Contemp Clin Trials. 2018 Mar 07; 68:1-6. PMID: 29524590.
      View in: PubMed
    4. Martin JW, Chen JC, Neidleman J, Tatsumi K, Hu J, Giudice LC, Greene WC, Roan NR. Potent and rapid activation of tropomyosin-receptor kinase A in endometrial stromal fibroblasts by seminal plasma. Biol Reprod. 2018 Mar 06. PMID: 29518187.
      View in: PubMed
    5. Aghajanova L, Houshdaran S, Balayan S, Manvelyan E, Irwin JC, Huddleston HG, Giudice LC. In vitro evidence that platelet-rich plasma stimulates cellular processes involved in endometrial regeneration. J Assist Reprod Genet. 2018 Feb 05. PMID: 29404863.
      View in: PubMed
    6. Aghajanova L, Houshdaran S, Irwin JC, Giudice LC. Effects of noncavity-distorting fibroids on endometrial gene expression and function. Biol Reprod. 2017 Oct 01; 97(4):564-576. PMID: 29025102.
      View in: PubMed
    7. Erikson DW, Barragan F, Piltonen TT, Chen JC, Balayan S, Irwin JC, Giudice LC. Stromal fibroblasts from perimenopausal endometrium exhibit a different transcriptome than those from the premenopausal endometrium. Biol Reprod. 2017 Sep 01; 97(3):387-399. PMID: 29024986.
      View in: PubMed
    8. Altmäe S, Koel M, Võsa U, Adler P, Suhorutšenko M, Laisk-Podar T, Kukushkina V, Saare M, Velthut-Meikas A, Krjutškov K, Aghajanova L, Lalitkumar PG, Gemzell-Danielsson K, Giudice L, Simón C, Salumets A. Meta-signature of human endometrial receptivity: a meta-analysis and validation study of transcriptomic biomarkers. Sci Rep. 2017 Aug 30; 7(1):10077. PMID: 28855728.
      View in: PubMed
    9. Taylor HS, Giudice LC, Lessey BA, Abrao MS, Kotarski J, Archer DF, Diamond MP, Surrey E, Johnson NP, Watts NB, Gallagher JC, Simon JA, Carr BR, Dmowski WP, Leyland N, Rowan JP, Duan WR, Ng J, Schwefel B, Thomas JW, Jain RI, Chwalisz K. Treatment of Endometriosis-Associated Pain with Elagolix, an Oral GnRH Antagonist. N Engl J Med. 2017 07 06; 377(1):28-40. PMID: 28525302.
      View in: PubMed
    10. Montgomery GW, Giudice LC. New Lessons about Endometriosis - Somatic Mutations and Disease Heterogeneity. N Engl J Med. 2017 05 11; 376(19):1881-1882. PMID: 28489997.
      View in: PubMed
    11. Neidleman JA, Chen JC, Kohgadai N, Müller JA, Laustsen A, Thavachelvam K, Jang KS, Stürzel CM, Jones JJ, Ochsenbauer C, Chitre A, Somsouk M, Garcia MM, Smith JF, Greenblatt RM, Münch J, Jakobsen MR, Giudice LC, Greene WC, Roan NR. Mucosal stromal fibroblasts markedly enhance HIV infection of CD4+ T cells. PLoS Pathog. 2017 Feb; 13(2):e1006163. PMID: 28207890.
      View in: PubMed
    12. Johnson NP, Hummelshoj L, Adamson GD, Keckstein J, Taylor HS, Abrao MS, Bush D, Kiesel L, Tamimi R, Sharpe-Timms KL, Rombauts L, Giudice LC. World Endometriosis Society consensus on the classification of endometriosis. Hum Reprod. 2017 02; 32(2):315-324. PMID: 27920089.
      View in: PubMed
    13. Arora R, Fries A, Oelerich K, Marchuk K, Sabeur K, Giudice LC, Laird DJ. Insights from imaging the implanting embryo and the uterine environment in three dimensions. Development. 2016 12 15; 143(24):4749-4754. PMID: 27836961.
      View in: PubMed
    14. Giudice LC. Challenging dogma: the endometrium has a microbiome with functional consequences! Am J Obstet Gynecol. 2016 12; 215(6):682-683. PMID: 27725136.
      View in: PubMed
    15. Rogers PA, Adamson GD, Al-Jefout M, Becker CM, D'Hooghe TM, Dunselman GA, Fazleabas A, Giudice LC, Horne AW, Hull ML, Hummelshoj L, Missmer SA, Montgomery GW, Stratton P, Taylor RN, Rombauts L, Saunders PT, Vincent K, Zondervan KT. Research Priorities for Endometriosis. Reprod Sci. 2017 02; 24(2):202-226. PMID: 27368878.
      View in: PubMed
    16. Giudice LC. Environmental toxicants: hidden players on the reproductive stage. Fertil Steril. 2016 Sep 15; 106(4):791-4. PMID: 27545021.
      View in: PubMed
    17. Houshdaran S, Nezhat CR, Vo KC, Zelenko Z, Irwin JC, Giudice LC. Aberrant Endometrial DNA Methylome and Associated Gene Expression in Women with Endometriosis. Biol Reprod. 2016 11; 95(5):93. PMID: 27535958.
      View in: PubMed
    18. Shanmugasundaram U, Hilton JF, Critchfield JW, Greenblatt RM, Giudice LC, Averbach S, Seidman D, Shacklett BL, Smith-McCune K. Effects of the levonorgestrel-releasing intrauterine device on the immune microenvironment of the human cervix and endometrium. Am J Reprod Immunol. 2016 08; 76(2):137-48. PMID: 27401588.
      View in: PubMed
    19. Aghajanova L, Altmäe S, Kasvandik S, Salumets A, Stavreus-Evers A, Giudice LC. Stanniocalcin-1 expression in normal human endometrium and dysregulation in endometriosis. Fertil Steril. 2016 Sep 01; 106(3):681-691.e1. PMID: 27322879; PMCID: PMC5010972 [Available on 09/01/17].
    20. Herndon CN, Aghajanova L, Balayan S, Erikson D, Barragan F, Goldfien G, Vo KC, Hawkins S, Giudice LC. Global Transcriptome Abnormalities of the Eutopic Endometrium From Women With Adenomyosis. Reprod Sci. 2016 10; 23(10):1289-303. PMID: 27233751.
      View in: PubMed
    21. Sutton PM, Giudice LC, Woodruff TJ. Moving from awareness to action on preventing patient exposure to toxic environmental chemicals. Am J Obstet Gynecol. 2016 05; 214(5):555-8. PMID: 27126615.
      View in: PubMed
    22. Barragan F, Irwin JC, Balayan S, Erikson DW, Chen JC, Houshdaran S, Piltonen TT, Spitzer TL, George A, Rabban JT, Nezhat C, Giudice LC. Human Endometrial Fibroblasts Derived from Mesenchymal Progenitors Inherit Progesterone Resistance and Acquire an Inflammatory Phenotype in the Endometrial Niche in Endometriosis. Biol Reprod. 2016 05; 94(5):118. PMID: 27075616.
      View in: PubMed
    23. Chen JC, Hoffman JR, Arora R, Perrone LA, Gonzalez-Gomez CJ, Vo KC, Laird DJ, Irwin JC, Giudice LC. Cryopreservation and recovery of human endometrial epithelial cells with high viability, purity, and functional fidelity. Fertil Steril. 2016 Feb; 105(2):501-10.e1. PMID: 26515378; PMCID: PMC4744114 [Available on 02/01/17].
    24. Di Renzo GC, Conry JA, Blake J, DeFrancesco MS, DeNicola N, Martin JN, McCue KA, Richmond D, Shah A, Sutton P, Woodruff TJ, van der Poel SZ, Giudice LC. International Federation of Gynecology and Obstetrics opinion on reproductive health impacts of exposure to toxic environmental chemicals. Int J Gynaecol Obstet. 2015 Dec; 131(3):219-25. PMID: 26433469.
      View in: PubMed
    25. Vannuccini S, Clifton VL, Fraser IS, Taylor HS, Critchley H, Giudice LC, Petraglia F. Infertility and reproductive disorders: impact of hormonal and inflammatory mechanisms on pregnancy outcome. Hum Reprod Update. 2016 Jan-Feb; 22(1):104-15. PMID: 26395640.
      View in: PubMed
    26. Bergman Å, Becher G, Blumberg B, Bjerregaard P, Bornman R, Brandt I, Casey SC, Frouin H, Giudice LC, Heindel JJ, Iguchi T, Jobling S, Kidd KA, Kortenkamp A, Lind PM, Muir D, Ochieng R, Ropstad E, Ross PS, Skakkebaek NE, Toppari J, Vandenberg LN, Woodruff TJ, Zoeller RT. Manufacturing doubt about endocrine disrupter science--A rebuttal of industry-sponsored critical comments on the UNEP/WHO report "State of the Science of Endocrine Disrupting Chemicals 2012". Regul Toxicol Pharmacol. 2015 Dec; 73(3):1007-17. PMID: 26239693.
      View in: PubMed
    27. Smith-McCune K, Chen JC, Greenblatt RM, Shanmugasundaram U, Shacklett BL, Hilton JF, Johnson B, Irwin JC, Giudice LC. Unexpected Inflammatory Effects of Intravaginal Gels (Universal Placebo Gel and Nonoxynol-9) on the Upper Female Reproductive Tract: A Randomized Crossover Study. PLoS One. 2015; 10(7):e0129769. PMID: 26177352; PMCID: PMC4503751.
    28. Fassbender A, Burney RO, O DF, D'Hooghe T, Giudice L. Update on Biomarkers for the Detection of Endometriosis. Biomed Res Int. 2015; 2015:130854. PMID: 26240814; PMCID: PMC4512573.
    29. Vercellini P, Giudice LC, Evers JL, Abrao MS. Reducing low-value care in endometriosis between limited evidence and unresolved issues: a proposal. Hum Reprod. 2015 Sep; 30(9):1996-2004. PMID: 26141710.
      View in: PubMed
    30. Heard ME, Velarde MC, Giudice LC, Simmen FA, Simmen RC. Krüppel-Like Factor 13 Deficiency in Uterine Endometrial Cells Contributes to Defective Steroid Hormone Receptor Signaling but Not Lesion Establishment in a Mouse Model of Endometriosis. Biol Reprod. 2015 Jun; 92(6):140. PMID: 25904015; PMCID: PMC4652611.
    31. Goldfien GA, Barragan F, Chen J, Takeda M, Irwin JC, Perry J, Greenblatt RM, Smith-McCune KK, Giudice LC. Progestin-Containing Contraceptives Alter Expression of Host Defense-Related Genes of the Endometrium and Cervix. Reprod Sci. 2015 Jul; 22(7):814-28. PMID: 25634912; PMCID: PMC4565478.
    32. Williams KE, Miroshnychenko O, Johansen EB, Niles RK, Sundaram R, Kannan K, Albertolle M, Zhou Y, Prasad N, Drake PM, Giudice LC, Hall SC, Witkowska HE, Buck Louis GM, Fisher SJ. Urine, peritoneal fluid and omental fat proteomes of reproductive age women: Endometriosis-related changes and associations with endocrine disrupting chemicals. J Proteomics. 2015 Jan 15; 113:194-205. PMID: 25284053; PMCID: PMC4467531.
    33. Rahmioglu N, Fassbender A, Vitonis AF, Tworoger SS, Hummelshoj L, D'Hooghe TM, Adamson GD, Giudice LC, Becker CM, Zondervan KT, Missmer SA. World Endometriosis Research Foundation Endometriosis Phenome and Biobanking Harmonization Project: III. Fluid biospecimen collection, processing, and storage in endometriosis research. Fertil Steril. 2014 Nov; 102(5):1233-43. PMID: 25256929.
      View in: PubMed
    34. Vitonis AF, Vincent K, Rahmioglu N, Fassbender A, Buck Louis GM, Hummelshoj L, Giudice LC, Stratton P, Adamson GD, Becker CM, Zondervan KT, Missmer SA. World Endometriosis Research Foundation Endometriosis Phenome and Biobanking Harmonization Project: II. Clinical and covariate phenotype data collection in endometriosis research. Fertil Steril. 2014 Nov; 102(5):1223-32. PMID: 25256930.
      View in: PubMed
    35. Tamaresis JS, Irwin JC, Goldfien GA, Rabban JT, Burney RO, Nezhat C, DePaolo LV, Giudice LC. Molecular classification of endometriosis and disease stage using high-dimensional genomic data. Endocrinology. 2014 Dec; 155(12):4986-99. PMID: 25243856; PMCID: PMC4239429.
    36. Fassbender A, Rahmioglu N, Vitonis AF, Viganò P, Giudice LC, D'Hooghe TM, Hummelshoj L, Adamson GD, Becker CM, Missmer SA, Zondervan KT. World Endometriosis Research Foundation Endometriosis Phenome and Biobanking Harmonisation Project: IV. Tissue collection, processing, and storage in endometriosis research. Fertil Steril. 2014 Nov; 102(5):1244-53. PMID: 25256928.
      View in: PubMed
    37. Houshdaran S, Zelenko Z, Irwin JC, Giudice LC. Human endometrial DNA methylome is cycle-dependent and is associated with gene expression regulation. Mol Endocrinol. 2014 Jul; 28(7):1118-35. PMID: 24877562; PMCID: PMC4075160.
    38. Chen JC, Johnson BA, Erikson DW, Piltonen TT, Barragan F, Chu S, Kohgadai N, Irwin JC, Greene WC, Giudice LC, Roan NR. Seminal plasma induces global transcriptomic changes associated with cell migration, proliferation and viability in endometrial epithelial cells and stromal fibroblasts. Hum Reprod. 2014 Jun; 29(6):1255-70. PMID: 24626806; PMCID: PMC4017943.
    39. Shanmugasundaram U, Critchfield JW, Pannell J, Perry J, Giudice LC, Smith-McCune K, Greenblatt RM, Shacklett BL. Phenotype and functionality of CD4+ and CD8+ T cells in the upper reproductive tract of healthy premenopausal women. Am J Reprod Immunol. 2014 Feb; 71(2):95-108. PMID: 24313954; PMCID: PMC3947236.
    40. Altmäe S, Esteban FJ, Stavreus-Evers A, Simón C, Giudice L, Lessey BA, Horcajadas JA, Macklon NS, D'Hooghe T, Campoy C, Fauser BC, Salamonsen LA, Salumets A. Guidelines for the design, analysis and interpretation of 'omics' data: focus on human endometrium. Hum Reprod Update. 2014 Jan-Feb; 20(1):12-28. PMID: 24082038; PMCID: PMC3845681.
    41. Bergman Å, Andersson AM, Becher G, van den Berg M, Blumberg B, Bjerregaard P, Bornehag CG, Bornman R, Brandt I, Brian JV, Casey SC, Fowler PA, Frouin H, Giudice LC, Iguchi T, Hass U, Jobling S, Juul A, Kidd KA, Kortenkamp A, Lind M, Martin OV, Muir D, Ochieng R, Olea N, Norrgren L, Ropstad E, Ross PS, Rudén C, Scheringer M, Skakkebaek NE, Söder O, Sonnenschein C, Soto A, Swan S, Toppari J, Tyler CR, Vandenberg LN, Vinggaard AM, Wiberg K, Zoeller RT. Science and policy on endocrine disrupters must not be mixed: a reply to a "common sense" intervention by toxicology journal editors. Environ Health. 2013 Aug 27; 12:69. PMID: 23981490; PMCID: PMC3765603.
    42. Carr B, Giudice L, Dmowski WP, O'Brien C, Jiang P, Burke J, Jimenez R, Hass S, Fuldeore M, Chwalisz K. Elagolix, an Oral GnRH Antagonist for Endometriosis-Associated Pain: A Randomized Controlled Study. J Endometr Pelvic Pain Disord. 2013 Jul; 5(3):105-115. PMID: 30320043.
      View in: PubMed
    43. Chen JC, Erikson DW, Piltonen TT, Meyer MR, Barragan F, McIntire RH, Tamaresis JS, Vo KC, Giudice LC, Irwin JC. Coculturing human endometrial epithelial cells and stromal fibroblasts alters cell-specific gene expression and cytokine production. Fertil Steril. 2013 Oct; 100(4):1132-43. PMID: 23849844.
      View in: PubMed
    44. Hyman RW, Fukushima M, Jiang H, Fung E, Rand L, Johnson B, Vo KC, Caughey AB, Hilton JF, Davis RW, Giudice LC. Diversity of the vaginal microbiome correlates with preterm birth. Reprod Sci. 2014 Jan; 21(1):32-40. PMID: 23715799; PMCID: PMC3857766.
    45. Fisher SJ, Giudice LC. Retrospective. Robert G. Edwards (1925-2013). Science. 2013 May 17; 340(6134):825. PMID: 23687039.
      View in: PubMed
    46. Buck Louis GM, Peterson CM, Chen Z, Croughan M, Sundaram R, Stanford J, Varner MW, Kennedy A, Giudice L, Fujimoto VY, Sun L, Wang L, Guo Y, Kannan K. Bisphenol A and phthalates and endometriosis: the Endometriosis: Natural History, Diagnosis and Outcomes Study. Fertil Steril. 2013 Jul; 100(1):162-9.e1-2. PMID: 23579005.
      View in: PubMed
    47. Afshar Y, Hastings J, Roqueiro D, Jeong JW, Giudice LC, Fazleabas AT. Changes in eutopic endometrial gene expression during the progression of experimental endometriosis in the baboon, Papio anubis. Biol Reprod. 2013 Feb; 88(2):44. PMID: 23284138; PMCID: PMC3589234.
    48. Rogers PA, D'Hooghe TM, Fazleabas A, Giudice LC, Montgomery GW, Petraglia F, Taylor RN. Defining future directions for endometriosis research: workshop report from the 2011 World Congress of Endometriosis In Montpellier, France. Reprod Sci. 2013 May; 20(5):483-99. PMID: 23427182; PMCID: PMC3635070.
    49. Louis GM, Peterson CM, Chen Z, Hediger ML, Croughan MS, Sundaram R, Stanford JB, Fujimoto VY, Varner MW, Giudice LC, Kennedy A, Sun L, Wu Q, Kannan K. Perfluorochemicals and endometriosis: the ENDO study. Epidemiology. 2012 Nov; 23(6):799-805. PMID: 22992575.
      View in: PubMed
    50. Meldrum DR, Chang RJ, Giudice LC, Balasch J, Barbieri RL. Role of decreased androgens in the ovarian response to stimulation in older women. Fertil Steril. 2013 Jan; 99(1):5-11. PMID: 23122826.
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    51. Burney RO, Giudice LC. Pathogenesis and pathophysiology of endometriosis. Fertil Steril. 2012 Sep; 98(3):511-9. PMID: 22819144; PMCID: PMC3836682.
    52. Buck Louis GM, Chen Z, Peterson CM, Hediger ML, Croughan MS, Sundaram R, Stanford JB, Varner MW, Fujimoto VY, Giudice LC, Trumble A, Parsons PJ, Kannan K. Persistent lipophilic environmental chemicals and endometriosis: the ENDO Study. Environ Health Perspect. 2012 Jun; 120(6):811-6. PMID: 22417635; PMCID: PMC3385438.
    53. Hyman RW, St Onge RP, Kim H, Tamaresis JS, Miranda M, Aparicio AM, Fukushima M, Pourmand N, Giudice LC, Davis RW. Molecular probe technology detects bacteria without culture. BMC Microbiol. 2012 Mar 09; 12:29. PMID: 22404909; PMCID: PMC3316761.
    54. Sutton P, Woodruff TJ, Perron J, Stotland N, Conry JA, Miller MD, Giudice LC. Toxic environmental chemicals: the role of reproductive health professionals in preventing harmful exposures. Am J Obstet Gynecol. 2012 Sep; 207(3):164-73. PMID: 22405527.
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    55. Spitzer TL, Rojas A, Zelenko Z, Aghajanova L, Erikson DW, Barragan F, Meyer M, Tamaresis JS, Hamilton AE, Irwin JC, Giudice LC. Perivascular human endometrial mesenchymal stem cells express pathways relevant to self-renewal, lineage specification, and functional phenotype. Biol Reprod. 2012 Feb; 86(2):58. PMID: 22075475; PMCID: PMC3290674.
    56. Pabona JM, Simmen FA, Nikiforov MA, Zhuang D, Shankar K, Velarde MC, Zelenko Z, Giudice LC, Simmen RC. Krüppel-like factor 9 and progesterone receptor coregulation of decidualizing endometrial stromal cells: implications for the pathogenesis of endometriosis. J Clin Endocrinol Metab. 2012 Mar; 97(3):E376-92. PMID: 22259059; PMCID: PMC3319212.
    57. Aghajanova L, Shen S, Rojas AM, Fisher SJ, Irwin JC, Giudice LC. Comparative transcriptome analysis of human trophectoderm and embryonic stem cell-derived trophoblasts reveal key participants in early implantation. Biol Reprod. 2012 Jan; 86(1):1-21. PMID: 21865555.
      View in: PubMed
    58. Hyman RW, Herndon CN, Jiang H, Palm C, Fukushima M, Bernstein D, Vo KC, Zelenko Z, Davis RW, Giudice LC. The dynamics of the vaginal microbiome during infertility therapy with in vitro fertilization-embryo transfer. J Assist Reprod Genet. 2012 Feb; 29(2):105-15. PMID: 22222853; PMCID: PMC3270134.
    59. Leach RE, Jessmon P, Coutifaris C, Kruger M, Myers ER, Ali-Fehmi R, Carson SA, Legro RS, Schlaff WD, Carr BR, Steinkampf MP, Silva S, Leppert PC, Giudice L, Diamond MP, Armant DR. High throughput, cell type-specific analysis of key proteins in human endometrial biopsies of women from fertile and infertile couples. Hum Reprod. 2012 Mar; 27(3):814-28. PMID: 22215622; PMCID: PMC3279126.
    60. Zelenko Z, Aghajanova L, Irwin JC, Giudice LC. Nuclear receptor, coregulator signaling, and chromatin remodeling pathways suggest involvement of the epigenome in the steroid hormone response of endometrium and abnormalities in endometriosis. Reprod Sci. 2012 Feb; 19(2):152-62. PMID: 22138541; PMCID: PMC3343132.
    61. White WB, Grady D, Giudice LC, Berry SM, Zborowski J, Snabes MC. A cardiovascular safety study of LibiGel (testosterone gel) in postmenopausal women with elevated cardiovascular risk and hypoactive sexual desire disorder. Am Heart J. 2012 Jan; 163(1):27-32. PMID: 22172433.
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    62. Fisher SJ, Giudice LC. SGK1: a fine balancing act for human pregnancy. Nat Med. 2011 Nov 07; 17(11):1348-9. PMID: 22064410.
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