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Linda Giudice, MD, PhD

Title(s)Professor, Ob/Gyn, Reproductive Sciences
SchoolSchool of Medicine
Address513 Parnassus Ave, HSE
San Francisco CA 94143
Phone415-502-4742
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    Other Positions
    Title(s)Obstetrics, Gynecology and Reproductive Sciences


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    Stanford UniversityM.D.1982School of Medicine

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    Linda C. Giudice, MD, PhD is Distinguished Professor, Chair Emerita, and the Robert B. Jaffe MD Endowed Professor in the Reproductive Sciences in the Department of Obstetrics, Gynecology and Reproductive Sciences at the University of California, San Francisco (UCSF). She is a biochemist and reproductive endocrinologist specializing in endometriosis and infertility. Her research focuses on human endometrial function and regeneration, genetics and epigenetics of endometriosis, placental-uterine interactions relevant to pregnancy outcomes, and evaluating the evidence of environmental impacts on reproductive health and human development. She has mentored over 250 students, fellows and faculty, authored > 300 peer-reviewed publications, and is co-editor of 6 textbooks on women’s health, reproductive environmental health, endocrinology, endometrium and endometriosis. She is Past-President of the American Society for Reproductive Medicine, the Society for Gynecologic Investigation, President of the World Endometriosis Society, President-elect of the International Federation of Fertility Societies, and Chair of the FIGO (International Federation of Gynecology and Obstetrics) Reproductive and Developmental Environmental Health Working Group. Dr. Giudice is on the UCSF Steering Committee on Women’s Precision Medicine, the March of Dimes Scientific Advisory Council, and is an elected member of the U.S. National Academy of Medicine and the U.S. National Academy of Inventors.

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    Collapse Research Activities and Funding
    Integrative Analysis of Genomic, Epigenomic and Phenotypic Data for Disease Stratification of Endometriosis
    NIH/NICHD R01HD089511Sep 26, 2016 - Apr 30, 2021
    Role: Principal Investigator
    Exploring HIV-Host Interactions in the Female Reproductive Tract
    NIH/NIAID P01AI083050Sep 1, 2009 - Aug 31, 2014
    Role: Co-Principal Investigator
    Origins and Biological Consequences of Human Infertility
    NIH/NICHD U54HD055764May 3, 2007 - Sep 29, 2011
    Role: Principal Investigator
    Center for Research, Innovation and Training in Reproduction and Infertility
    NIH/NICHD P50HD055764Apr 1, 2007 - Mar 31, 2023
    Role: Principal Investigator
    Summit on Environmental Challenges to Reproductive Health and Fertility
    NIH/NIEHS R13ES015427Sep 15, 2006 - Aug 31, 2007
    Role: Principal Investigator
    Mentoring &Interdisciplinary Research in Women's Health
    NIH/NICHD K12HD043452Sep 27, 2002 - Jul 31, 2007
    Role: Co-Principal Investigator
    Gordon Research Conference on Reproductive Tract Biology
    NIH/NICHD R13HD042663Jun 19, 2002 - May 31, 2003
    Role: Principal Investigator
    Federally Registered Human Embryonic Stem Cell Center
    NIH/NCRR R24RR017498May 1, 2002 - Jul 31, 2007
    Role: Principal Investigator
    Role of IGF-II in Human Trophoblast-Decidua Interactions
    NIH/NICHD U01HD042298Apr 1, 2002 - Sep 30, 2005
    Role: Principal Investigator
    HYPOXIA, IGFBP-1, AND HUMAN FETAL GROWTH
    NIH/NICHD R01HD036732Mar 1, 2000 - Feb 28, 2004
    Role: Principal Investigator
    Women's Reproductive Health Research
    NIH/NICHD K12HD001262Sep 30, 1998 - Sep 29, 2009
    Role: Co-Principal Investigator
    Gonadal and Endometrial Function in Human Reproduction
    NIH/NICHD U54HD031398Apr 1, 1998 - Mar 31, 2008
    Role: Co-Principal Investigator
    ROLE OF IGF IN HUMAN OVARY
    NIH/NICHD R01HD031579May 1, 1994 - Sep 30, 2008
    Role: Principal Investigator
    INSULIN-LIKE GROWTH FACTOR SYSTEM IN OVIDUCT
    NIH/NICHD R03HD028079May 1, 1991 - Apr 30, 1993
    Role: Principal Investigator
    IGF BINDING PROTEINS AND HUMAN ENDOMETRIUM
    NIH/NICHD R01HD025220Apr 1, 1990 - Jul 31, 2002
    Role: Principal Investigator
    GENE EXPRESSION IN ENDOMETRIUM
    NIH/NICHD R29HD025220Apr 1, 1990 - Mar 31, 1996
    Role: Principal Investigator
    General Clinical Research Center
    NIH M01RR000070Dec 1, 1978 - Nov 30, 2011
    Role: Co-Investigator

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Cytotrophoblast extracellular vesicles enhance decidual cell secretion of immune modulators via TNF-alpha. Development. 2020 Aug 03. Taylor SK, Houshdaran S, Robinson JF, Gormley MJ, Kwan EY, Kapidzic M, Schilling B, Giudice LC, Fisher SJ. PMID: 32747437.
      View in: PubMed   Mentions:    Fields:    
    2. m6A RNA Methylation Regulators Contribute to Eutopic Endometrium and Myometrium Dysfunction in Adenomyosis. Front Genet. 2020; 11:716. Zhai J, Li S, Sen S, Opoku-Anane J, Du Y, Chen ZJ, Giudice LC. PMID: 32719721.
      View in: PubMed   Mentions:
    3. Steroid hormones regulate genome-wide epigenetic programming and gene transcription in human endometrial cells with marked aberrancies in endometriosis. PLoS Genet. 2020 06; 16(6):e1008601. Houshdaran S, Oke AB, Fung JC, Vo KC, Nezhat C, Giudice LC. PMID: 32555663.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    4. A Clarion Warning About Pregnancy Outcomes and the Climate Crisis. JAMA Netw Open. 2020 Jun 01; 3(6):e208811. Giudice LC. PMID: 32556255.
      View in: PubMed   Mentions:    Fields:    
    5. HIV efficiently infects T cells from the endometrium and remodels them to promote systemic viral spread. Elife. 2020 May 26; 9. Ma T, Luo X, George AF, Mukherjee G, Sen N, Spitzer TL, Giudice LC, Greene WC, Roan NR. PMID: 32452381.
      View in: PubMed   Mentions: 1     Fields:    
    6. Parallel studies of mucosal immunity in the reproductive and gastrointestinal mucosa of HIV-infected women. Am J Reprod Immunol. 2020 Jul; 84(1):e13246. Shanmugasundaram U, Critchfield JW, Giudice LC, Smith-McCune K, Greenblatt RM, Shacklett BL. PMID: 32301548.
      View in: PubMed   Mentions:    Fields:    
    7. Authors' Reply. J Minim Invasive Gynecol. 2020 Sep - Oct; 27(6):1427. Montgomery GW, Mortlock S, Giudice LC. PMID: 32339756.
      View in: PubMed   Mentions:    Fields:    
    8. Differential Effects of the Hormonal and Copper Intrauterine Device on the Endometrial Transcriptome. Sci Rep. 2020 Apr 23; 10(1):6888. Smith-McCune K, Thomas R, Averbach S, Seidman D, Takeda M, Houshdaran S, Giudice LC. PMID: 32327684.
      View in: PubMed   Mentions:    Fields:    
    9. Progestins Related to Progesterone and Testosterone Elicit Divergent Human Endometrial Transcriptomes and Biofunctions. Int J Mol Sci. 2020 Apr 09; 21(7). Houshdaran S, Chen JC, Vallvé-Juanico J, Balayan S, Vo KC, Smith-McCune K, Greenblatt RM, Irwin JC, Giudice LC. PMID: 32283828.
      View in: PubMed   Mentions:    Fields:    
    10. Seminal plasma promotes decidualization of endometrial stromal fibroblasts in vitro from women with and without inflammatory disorders in a manner dependent on interleukin-11 signaling. Hum Reprod. 2020 Mar 27; 35(3):617-640. George AF, Jang KS, Nyegaard M, Neidleman J, Spitzer TL, Xie G, Chen JC, Herzig E, Laustsen A, Marques de Menezes EG, Houshdaran S, Pilcher CD, Norris PJ, Jakobsen MR, Greene WC, Giudice LC, Roan NR. PMID: 32219408.
      View in: PubMed   Mentions:    Fields:    
    11. A Pilot Cancer-Phenome Biobanking System in a Low-Resource Southeast Asian Setting: The Philippine General Hospital Biobank Experience. Biopreserv Biobank. 2020 Jun; 18(3):180-188. Sajo MEJV, Teves JMY, Corachea AJM, Diaz LA, Chan AFO, Valparaiso AP, Dy Echo AVV, Macalindong SS, Uy GLB, Dofitas RB, Habana MAE, Gerona RR, Irwin JC, Giudice LC, Velarde MC. PMID: 32202927.
      View in: PubMed   Mentions:    Fields:    
    12. Macrophages display proinflammatory phenotypes in the eutopic endometrium of women with endometriosis with relevance to an infectious etiology of the disease. Fertil Steril. 2019 12; 112(6):1118-1128. Vallvé-Juanico J, Santamaria X, Vo KC, Houshdaran S, Giudice LC. PMID: 31843088.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    13. Should Genetics Now Be Considered the Pre-eminent Etiologic Factor in Endometriosis? J Minim Invasive Gynecol. 2020 02; 27(2):280-286. Montgomery GW, Mortlock S, Giudice LC. PMID: 31683028.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    14. Before the beginning: environmental exposures and reproductive and obstetrical outcomes. Fertil Steril. 2019 10; 112(4):613-621. Segal TR, Giudice LC. PMID: 31561863.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    15. Reprint of: Pathogenesis and pathophysiology of endometriosis. Fertil Steril. 2019 10; 112(4 Suppl1):e153-e161. Burney RO, Giudice LC. PMID: 31623726.
      View in: PubMed   Mentions:    Fields:    
    16. 25 historic papers: an ASRM 75th birthday gift from Fertility and Sterility. Fertil Steril. 2019 10; 112(4 Suppl1):e2-e27. Niederberger C, Pellicer A, Simon C, Kathrins M, Goldstein M, Sigman M, Schlegel PN, Munné S, Gardner DK, Cobo A, Coutifaris C, Donnez J, Taylor HS, Giudice LC, Fauser BCJM, Lindheim SR, Rosenwaks Z, Casper RF, de Ziegler D, Gibbons WE, Paulson RJ, Laufer N, Klock SC, Mendola P, Sauer MV. PMID: 31623734.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    17. The endometrial immune environment of women with endometriosis. Hum Reprod Update. 2019 09 11; 25(5):564-591. Vallvé-Juanico J, Houshdaran S, Giudice LC. PMID: 31424502.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    18. Assessing research gaps and unmet needs in endometriosis. Am J Obstet Gynecol. 2019 08; 221(2):86-94. As-Sanie S, Black R, Giudice LC, Gray Valbrun T, Gupta J, Jones B, Laufer MR, Milspaw AT, Missmer SA, Norman A, Taylor RN, Wallace K, Williams Z, Yong PJ, Nebel RA. PMID: 30790565.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    19. Clinical diagnosis of endometriosis: a call to action. Am J Obstet Gynecol. 2019 04; 220(4):354.e1-354.e12. Agarwal SK, Chapron C, Giudice LC, Laufer MR, Leyland N, Missmer SA, Singh SS, Taylor HS. PMID: 30625295.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    20. Establishing the global working group on Reproductive and Developmental Environmental Health (RDEH): practicum of a global resource. Glob Reprod Health. 2018 Sep; 3(3). Power AM, Woodruff TJ, Conry JA, Giudice LC. PMID: 31245658.
      View in: PubMed   Mentions:
    21. Potent and rapid activation of tropomyosin-receptor kinase A in endometrial stromal fibroblasts by seminal plasma. Biol Reprod. 2018 08 01; 99(2):336-348. Martin JW, Chen JC, Neidleman J, Tatsumi K, Hu J, Giudice LC, Greene WC, Roan NR. PMID: 29518187.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    22. Forty years of IVF. Fertil Steril. 2018 07 15; 110(2):185-324.e5. Niederberger C, Pellicer A, Cohen J, Gardner DK, Palermo GD, O'Neill CL, Chow S, Rosenwaks Z, Cobo A, Swain JE, Schoolcraft WB, Frydman R, Bishop LA, Aharon D, Gordon C, New E, Decherney A, Tan SL, Paulson RJ, Goldfarb JM, Brännström M, Donnez J, Silber S, Dolmans MM, Simpson JL, Handyside AH, Munné S, Eguizabal C, Montserrat N, Izpisua Belmonte JC, Trounson A, Simon C, Tulandi T, Giudice LC, Norman RJ, Hsueh AJ, Sun Y, Laufer N, Kochman R, Eldar-Geva T, Lunenfeld B, Ezcurra D, D'Hooghe T, Fauser BCJM, Tarlatzis BC, Meldrum DR, Casper RF, Fatemi HM, Devroey P, Galliano D, Wikland M, Sigman M, Schoor RA, Goldstein M, Lipshultz LI, Schlegel PN, Hussein A, Oates RD, Brannigan RE, Ross HE, Pennings G, Klock SC, Brown S, Van Steirteghem A, Rebar RW, LaBarbera AR. PMID: 30053940.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    23. Long-Term Outcomes of Elagolix in Women With Endometriosis: Results From Two Extension Studies. Obstet Gynecol. 2018 07; 132(1):147-160. Surrey E, Taylor HS, Giudice L, Lessey BA, Abrao MS, Archer DF, Diamond MP, Johnson NP, Watts NB, Gallagher JC, Simon JA, Carr BR, Dmowski WP, Leyland N, Singh SS, Rechberger T, Agarwal SK, Duan WR, Schwefel B, Thomas JW, Peloso PM, Ng J, Soliman AM, Chwalisz K. PMID: 29889764.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCTClinical Trials
    24. Evaluation, validation and refinement of noninvasive diagnostic biomarkers for endometriosis (ENDOmarker): A protocol to phenotype bio-specimens for discovery and validation. Contemp Clin Trials. 2018 05; 68:1-6. Barnhart K, Giudice L, Young S, Thomas T, Diamond MP, Segars J, Youssef WA, Krawetz S, Santoro N, Eisenberg E, Zhang H. PMID: 29524590.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    25. In vitro evidence that platelet-rich plasma stimulates cellular processes involved in endometrial regeneration. J Assist Reprod Genet. 2018 May; 35(5):757-770. Aghajanova L, Houshdaran S, Balayan S, Manvelyan E, Irwin JC, Huddleston HG, Giudice LC. PMID: 29404863.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    26. Effects of noncavity-distorting fibroids on endometrial gene expression and function. Biol Reprod. 2017 Oct 01; 97(4):564-576. Aghajanova L, Houshdaran S, Irwin JC, Giudice LC. PMID: 29025102.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    27. Stromal fibroblasts from perimenopausal endometrium exhibit a different transcriptome than those from the premenopausal endometrium. Biol Reprod. 2017 Sep 01; 97(3):387-399. Erikson DW, Barragan F, Piltonen TT, Chen JC, Balayan S, Irwin JC, Giudice LC. PMID: 29024986.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    28. Meta-signature of human endometrial receptivity: a meta-analysis and validation study of transcriptomic biomarkers. Sci Rep. 2017 08 30; 7(1):10077. Altmäe S, Koel M, Võsa U, Adler P, Suhorutšenko M, Laisk-Podar T, Kukushkina V, Saare M, Velthut-Meikas A, Krjutškov K, Aghajanova L, Lalitkumar PG, Gemzell-Danielsson K, Giudice L, Simón C, Salumets A. PMID: 28855728.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    29. Treatment of Endometriosis-Associated Pain with Elagolix, an Oral GnRH Antagonist. N Engl J Med. 2017 07 06; 377(1):28-40. Taylor HS, Giudice LC, Lessey BA, Abrao MS, Kotarski J, Archer DF, Diamond MP, Surrey E, Johnson NP, Watts NB, Gallagher JC, Simon JA, Carr BR, Dmowski WP, Leyland N, Rowan JP, Duan WR, Ng J, Schwefel B, Thomas JW, Jain RI, Chwalisz K. PMID: 28525302.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCTClinical Trials
    30. New Lessons about Endometriosis - Somatic Mutations and Disease Heterogeneity. N Engl J Med. 2017 05 11; 376(19):1881-1882. Montgomery GW, Giudice LC. PMID: 28489997.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    31. Mucosal stromal fibroblasts markedly enhance HIV infection of CD4+ T cells. PLoS Pathog. 2017 02; 13(2):e1006163. Neidleman JA, Chen JC, Kohgadai N, Müller JA, Laustsen A, Thavachelvam K, Jang KS, Stürzel CM, Jones JJ, Ochsenbauer C, Chitre A, Somsouk M, Garcia MM, Smith JF, Greenblatt RM, Münch J, Jakobsen MR, Giudice LC, Greene WC, Roan NR. PMID: 28207890.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    32. Effects of depot-medroxyprogesterone acetate on the immune microenvironment of the human cervix and endometrium: implications for HIV susceptibility. Mucosal Immunol. 2017 09; 10(5):1270-1278. Smith-McCune KK, Hilton JF, Shanmugasundaram U, Critchfield JW, Greenblatt RM, Seidman D, Averbach S, Giudice LC, Shacklett BL. PMID: 28051087.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    33. World Endometriosis Society consensus on the classification of endometriosis. Hum Reprod. 2017 02; 32(2):315-324. Johnson NP, Hummelshoj L, Adamson GD, Keckstein J, Taylor HS, Abrao MS, Bush D, Kiesel L, Tamimi R, Sharpe-Timms KL, Rombauts L, Giudice LC. PMID: 27920089.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    34. Insights from imaging the implanting embryo and the uterine environment in three dimensions. Development. 2016 12 15; 143(24):4749-4754. Arora R, Fries A, Oelerich K, Marchuk K, Sabeur K, Giudice LC, Laird DJ. PMID: 27836961.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    35. Challenging dogma: the endometrium has a microbiome with functional consequences! Am J Obstet Gynecol. 2016 12; 215(6):682-683. Giudice LC. PMID: 27725136.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    36. Research Priorities for Endometriosis. Reprod Sci. 2017 02; 24(2):202-226. Rogers PA, Adamson GD, Al-Jefout M, Becker CM, D'Hooghe TM, Dunselman GA, Fazleabas A, Giudice LC, Horne AW, Hull ML, Hummelshoj L, Missmer SA, Montgomery GW, Stratton P, Taylor RN, Rombauts L, Saunders PT, Vincent K, Zondervan KT. PMID: 27368878.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    37. Environmental toxicants: hidden players on the reproductive stage. Fertil Steril. 2016 Sep 15; 106(4):791-4. Giudice LC. PMID: 27545021.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansPHPublic Health
    38. Aberrant Endometrial DNA Methylome and Associated Gene Expression in Women with Endometriosis. Biol Reprod. 2016 11; 95(5):93. Houshdaran S, Nezhat CR, Vo KC, Zelenko Z, Irwin JC, Giudice LC. PMID: 27535958.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    39. Effects of the levonorgestrel-releasing intrauterine device on the immune microenvironment of the human cervix and endometrium. Am J Reprod Immunol. 2016 08; 76(2):137-48. Shanmugasundaram U, Hilton JF, Critchfield JW, Greenblatt RM, Giudice LC, Averbach S, Seidman D, Shacklett BL, Smith-McCune K. PMID: 27401588.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCellsCTClinical Trials
    40. Stanniocalcin-1 expression in normal human endometrium and dysregulation in endometriosis. Fertil Steril. 2016 Sep 01; 106(3):681-691.e1. Aghajanova L, Altmäe S, Kasvandik S, Salumets A, Stavreus-Evers A, Giudice LC. PMID: 27322879.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    41. Global Transcriptome Abnormalities of the Eutopic Endometrium From Women With Adenomyosis. Reprod Sci. 2016 10; 23(10):1289-303. Herndon CN, Aghajanova L, Balayan S, Erikson D, Barragan F, Goldfien G, Vo KC, Hawkins S, Giudice LC. PMID: 27233751.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    42. Moving from awareness to action on preventing patient exposure to toxic environmental chemicals. Am J Obstet Gynecol. 2016 05; 214(5):555-8. Sutton PM, Giudice LC, Woodruff TJ. PMID: 27126615.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansPHPublic Health
    43. Human Endometrial Fibroblasts Derived from Mesenchymal Progenitors Inherit Progesterone Resistance and Acquire an Inflammatory Phenotype in the Endometrial Niche in Endometriosis. Biol Reprod. 2016 05; 94(5):118. Barragan F, Irwin JC, Balayan S, Erikson DW, Chen JC, Houshdaran S, Piltonen TT, Spitzer TL, George A, Rabban JT, Nezhat C, Giudice LC. PMID: 27075616.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    44. Cryopreservation and recovery of human endometrial epithelial cells with high viability, purity, and functional fidelity. Fertil Steril. 2016 Feb; 105(2):501-10.e1. Chen JC, Hoffman JR, Arora R, Perrone LA, Gonzalez-Gomez CJ, Vo KC, Laird DJ, Irwin JC, Giudice LC. PMID: 26515378.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    45. International Federation of Gynecology and Obstetrics opinion on reproductive health impacts of exposure to toxic environmental chemicals. Int J Gynaecol Obstet. 2015 Dec; 131(3):219-25. Di Renzo GC, Conry JA, Blake J, DeFrancesco MS, DeNicola N, Martin JN, McCue KA, Richmond D, Shah A, Sutton P, Woodruff TJ, van der Poel SZ, Giudice LC. PMID: 26433469.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansPHPublic Health
    46. Infertility and reproductive disorders: impact of hormonal and inflammatory mechanisms on pregnancy outcome. Hum Reprod Update. 2016 Jan-Feb; 22(1):104-15. Vannuccini S, Clifton VL, Fraser IS, Taylor HS, Critchley H, Giudice LC, Petraglia F. PMID: 26395640.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    47. Manufacturing doubt about endocrine disrupter science--A rebuttal of industry-sponsored critical comments on the UNEP/WHO report "State of the Science of Endocrine Disrupting Chemicals 2012". Regul Toxicol Pharmacol. 2015 Dec; 73(3):1007-17. Bergman Å, Becher G, Blumberg B, Bjerregaard P, Bornman R, Brandt I, Casey SC, Frouin H, Giudice LC, Heindel JJ, Iguchi T, Jobling S, Kidd KA, Kortenkamp A, Lind PM, Muir D, Ochieng R, Ropstad E, Ross PS, Skakkebaek NE, Toppari J, Vandenberg LN, Woodruff TJ, Zoeller RT. PMID: 26239693.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    48. Unexpected Inflammatory Effects of Intravaginal Gels (Universal Placebo Gel and Nonoxynol-9) on the Upper Female Reproductive Tract: A Randomized Crossover Study. PLoS One. 2015; 10(7):e0129769. Smith-McCune K, Chen JC, Greenblatt RM, Shanmugasundaram U, Shacklett BL, Hilton JF, Johnson B, Irwin JC, Giudice LC. PMID: 26177352.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    49. Update on Biomarkers for the Detection of Endometriosis. Biomed Res Int. 2015; 2015:130854. Fassbender A, Burney RO, O DF, D'Hooghe T, Giudice L. PMID: 26240814.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    50. Reducing low-value care in endometriosis between limited evidence and unresolved issues: a proposal. Hum Reprod. 2015 Sep; 30(9):1996-2004. Vercellini P, Giudice LC, Evers JL, Abrao MS. PMID: 26141710.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    51. Krüppel-Like Factor 13 Deficiency in Uterine Endometrial Cells Contributes to Defective Steroid Hormone Receptor Signaling but Not Lesion Establishment in a Mouse Model of Endometriosis. Biol Reprod. 2015 Jun; 92(6):140. Heard ME, Velarde MC, Giudice LC, Simmen FA, Simmen RC. PMID: 25904015.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    52. Endometrial stromal fibroblasts from women with polycystic ovary syndrome have impaired progesterone-mediated decidualization, aberrant cytokine profiles and promote enhanced immune cell migration in vitro. Hum Reprod. 2015 May; 30(5):1203-15. Piltonen TT, Chen JC, Khatun M, Kangasniemi M, Liakka A, Spitzer T, Tran N, Huddleston H, Irwin JC, Giudice LC. PMID: 25750105.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    53. Progestin-Containing Contraceptives Alter Expression of Host Defense-Related Genes of the Endometrium and Cervix. Reprod Sci. 2015 Jul; 22(7):814-28. Goldfien GA, Barragan F, Chen J, Takeda M, Irwin JC, Perry J, Greenblatt RM, Smith-McCune KK, Giudice LC. PMID: 25634912.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    54. Urine, peritoneal fluid and omental fat proteomes of reproductive age women: Endometriosis-related changes and associations with endocrine disrupting chemicals. J Proteomics. 2015 Jan 15; 113:194-205. Williams KE, Miroshnychenko O, Johansen EB, Niles RK, Sundaram R, Kannan K, Albertolle M, Zhou Y, Prasad N, Drake PM, Giudice LC, Hall SC, Witkowska HE, Buck Louis GM, Fisher SJ. PMID: 25284053.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCTClinical Trials
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    128. Controlled ovarian stimulation induces a functional genomic delay of the endometrium with potential clinical implications. J Clin Endocrinol Metab. 2008 Nov; 93(11):4500-10. Horcajadas JA, Mínguez P, Dopazo J, Esteban FJ, Domínguez F, Giudice LC, Pellicer A, Simón C. PMID: 18697870.
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    129. VEGF blockade inhibits angiogenesis and reepithelialization of endometrium. FASEB J. 2008 Oct; 22(10):3571-80. Fan X, Krieg S, Kuo CJ, Wiegand SJ, Rabinovitch M, Druzin ML, Brenner RM, Giudice LC, Nayak NR. PMID: 18606863.
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    130. Endometrial gene expression in early pregnancy: lessons from human ectopic pregnancy. Reprod Sci. 2008 Oct; 15(8):797-816. Savaris RF, Hamilton AE, Lessey BA, Giudice LC. PMID: 18591649.
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    131. Extended-release metformin does not reduce the clomiphene citrate dose required to induce ovulation in polycystic ovary syndrome. J Clin Endocrinol Metab. 2008 Aug; 93(8):3124-7. Cataldo NA, Barnhart HX, Legro RS, Myers ER, Schlaff WD, Carr BR, Diamond MP, Carson SA, Steinkampf MP, Coutifaris C, McGovern PG, Gosman G, Nestler JE, Giudice LC. PMID: 18505764.
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    132. Developmental competence of immature and failed/abnormally fertilized human oocytes in nuclear transfer. Reprod Biomed Online. 2008 May; 16(5):684-93. McElroy SL, Kee K, Tran N, Menses J, Giudice LC, Reijo Pera RA. PMID: 18492373.
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    133. The impact of ovarian stimulation with recombinant FSH in combination with GnRH antagonist on the endometrial transcriptome in the window of implantation. Reprod Sci. 2008 Apr; 15(4):357-65. Macklon NS, van der Gaast MH, Hamilton A, Fauser BC, Giudice LC. PMID: 18497344.
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    134. Proceedings of the Summit on Environmental Challenges to Reproductive Health and Fertility: executive summary. Fertil Steril. 2008 Feb; 89(2 Suppl):e1-e20. Woodruff TJ, Carlson A, Schwartz JM, Giudice LC. PMID: 18308046.
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    135. Proceedings of the Summit on Environmental Challenges to Reproductive Health and Fertility: executive summary. Fertil Steril. 2008 Feb; 89(2):281-300. Woodruff TJ, Carlson A, Schwartz JM, Giudice LC. PMID: 18275883.
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    136. Expression of membrane progesterone receptors on human T lymphocytes and Jurkat cells and activation of G-proteins by progesterone. J Endocrinol. 2008 Jan; 196(1):67-77. Dosiou C, Hamilton AE, Pang Y, Overgaard MT, Tulac S, Dong J, Thomas P, Giudice LC. PMID: 18180318.
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    137. Medication adherence and treatment success in the National Institute of Child Health and Human Development-Reproductive Medicine Network's Pregnancy in Polycystic Ovary Syndrome Trial. Fertil Steril. 2008 Oct; 90(4):1283-6. McGovern PG, Carson SA, Barnhart HX, Myers ER, Legro RS, Diamond MP, Carr BR, Schlaff WD, Coutifaris C, Cataldo NA, Steinkampf MP, Nestler JE, Gosman G, Leppert PC, Giudice LC. PMID: 18082737.
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    138. Ovulatory response to treatment of polycystic ovary syndrome is associated with a polymorphism in the STK11 gene. J Clin Endocrinol Metab. 2008 Mar; 93(3):792-800. Legro RS, Barnhart HX, Schlaff WD, Carr BR, Diamond MP, Carson SA, Steinkampf MP, Coutifaris C, McGovern PG, Cataldo NA, Gosman GG, Nestler JE, Giudice LC, Ewens KG, Spielman RS, Leppert PC, Myers ER. PMID: 18000088.
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    139. The influence of hydrosalpinx on markers of endometrial receptivity. Semin Reprod Med. 2007 Nov; 25(6):476-82. Savaris RF, Giudice LC. PMID: 17960532.
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    140. Uterine receptivity to human embryonic implantation: histology, biomarkers, and transcriptomics. Semin Cell Dev Biol. 2008 Apr; 19(2):204-11. Aghajanova L, Hamilton AE, Giudice LC. PMID: 18035563.
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    141. Gene expression analysis of endometrium reveals progesterone resistance and candidate susceptibility genes in women with endometriosis. Endocrinology. 2007 Aug; 148(8):3814-26. Burney RO, Talbi S, Hamilton AE, Vo KC, Nyegaard M, Nezhat CR, Lessey BA, Giudice LC. PMID: 17510236.
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    142. Clomiphene, metformin, or both for infertility in the polycystic ovary syndrome. N Engl J Med. 2007 Feb 08; 356(6):551-66. Legro RS, Barnhart HX, Schlaff WD, Carr BR, Diamond MP, Carson SA, Steinkampf MP, Coutifaris C, McGovern PG, Cataldo NA, Gosman GG, Nestler JE, Giudice LC, Leppert PC, Myers ER. PMID: 17287476.
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    143. Utility of screening for other causes of infertility in women with "known" polycystic ovary syndrome. Fertil Steril. 2007 Feb; 87(2):442-4. McGovern PG, Legro RS, Myers ER, Barnhart HX, Carson SA, Diamond MP, Carr BR, Schlaff WD, Coutifaris C, Steinkampf MP, Nestler JE, Gosman G, Leppert PC, Giudice LC. PMID: 17141768.
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    144. Decidual stromal cell response to paracrine signals from the trophoblast: amplification of immune and angiogenic modulators. Biol Reprod. 2007 Jan; 76(1):102-17. Hess AP, Hamilton AE, Talbi S, Dosiou C, Nyegaard M, Nayak N, Genbecev-Krtolica O, Mavrogianis P, Ferrer K, Kruessel J, Fazleabas AT, Fisher SJ, Giudice LC. PMID: 17021345.
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    145. Cytotrophoblast induction of arterial apoptosis and lymphangiogenesis in an in vivo model of human placentation. J Clin Invest. 2006 Oct; 116(10):2643-52. Red-Horse K, Rivera J, Schanz A, Zhou Y, Winn V, Kapidzic M, Maltepe E, Okazaki K, Kochman R, Vo KC, Giudice L, Erlebacher A, McCune JM, Stoddart CA, Fisher SJ. PMID: 16998586.
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    146. Participation of mitogen-activated protein kinase in luteinizing hormone-induced differential regulation of steroidogenesis and steroidogenic gene expression in mural and cumulus granulosa cells of mouse preovulatory follicles. Biol Reprod. 2006 Dec; 75(6):859-67. Su YQ, Nyegaard M, Overgaard MT, Qiao J, Giudice LC. PMID: 16943367.
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    147. Infertility and the environment: the medical context. Semin Reprod Med. 2006 Jul; 24(3):129-33. Giudice LC. PMID: 16804810.
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    148. A twenty-first century research agenda for polycystic ovary syndrome. Best Pract Res Clin Endocrinol Metab. 2006 Jun; 20(2):331-6. Legro RS, Azziz R, Giudice L. PMID: 16772161.
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    149. Endometrium in PCOS: Implantation and predisposition to endocrine CA. Best Pract Res Clin Endocrinol Metab. 2006 Jun; 20(2):235-44. Giudice LC. PMID: 16772154.
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    150. Dickkopf-1, an inhibitor of Wnt signaling, is regulated by progesterone in human endometrial stromal cells. J Clin Endocrinol Metab. 2006 Apr; 91(4):1453-61. Tulac S, Overgaard MT, Hamilton AE, Jumbe NL, Suchanek E, Giudice LC. PMID: 16449346.
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    151. The science behind 25 years of ovarian stimulation for in vitro fertilization. Endocr Rev. 2006 Apr; 27(2):170-207. Macklon NS, Stouffer RL, Giudice LC, Fauser BC. PMID: 16434510.
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    152. Expression, localization and hormonal control of angiopoietin-1 in the rhesus macaque endometrium: potential role in spiral artery growth. Mol Hum Reprod. 2005 Nov; 11(11):791-9. Nayak NR, Kuo CJ, Desai TA, Wiegand SJ, Lasley BL, Giudice LC, Brenner RM. PMID: 16390855.
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    153. Angiopoietin-1 and -2 mRNA and protein expression in mouse preimplantation embryos and uteri suggests a role in angiogenesis during implantation. Reprod Fertil Dev. 2006; 18(5):509-16. Hess AP, Hirchenhain J, Schanz A, Talbi S, Hamilton AE, Giudice LC, Krüssel JS. PMID: 16836957.
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    154. Literature watch. Cytotrophoblast induction of arterial apoptosis and lymphangiogenesis in an in vivo model of human placentation. Lymphat Res Biol. 2006; 4(4):229-42. Red-Horse K, Rivera J, Schanz A, Zhou Y, Winn V, Kapidzic M, Maltepe E, Okazaki K, Kochman R, Vo KC, Giudice L, Erlebacher A, McCune JM, Stoddart CA, Fisher SJ. PMID: 17394406.
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    155. Application of functional genomics to primate endometrium: insights into biological processes. Reprod Biol Endocrinol. 2006; 4 Suppl 1:S4. Giudice LC. PMID: 17118168.
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    156. Role of laparoscopic treatment of endometriosis in patients with failed in vitro fertilization cycles. Fertil Steril. 2005 Dec; 84(6):1574-8. Littman E, Giudice L, Lathi R, Berker B, Milki A, Nezhat C. PMID: 16359945.
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    157. The dilemma of endometriosis: is consensus possible with an enigma? Fertil Steril. 2005 Dec; 84(6):1587-8. Nezhat C, Littman ED, Lathi RB, Berker B, Westphal LM, Giudice LC, Milki AA. PMID: 16359950.
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    158. Molecular phenotyping of human endometrium distinguishes menstrual cycle phases and underlying biological processes in normo-ovulatory women. Endocrinology. 2006 Mar; 147(3):1097-121. Talbi S, Hamilton AE, Vo KC, Tulac S, Overgaard MT, Dosiou C, Le Shay N, Nezhat CN, Kempson R, Lessey BA, Nayak NR, Giudice LC. PMID: 16306079.
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    159. IVF results in de novo DNA methylation and histone methylation at an Igf2-H19 imprinting epigenetic switch. Mol Hum Reprod. 2005 Sep; 11(9):631-40. Li T, Vu TH, Ulaner GA, Littman E, Ling JQ, Chen HL, Hu JF, Behr B, Giudice L, Hoffman AR. PMID: 16219628.
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    160. Metabolic and ovarian effects of rosiglitazone treatment for 12 weeks in insulin-resistant women with polycystic ovary syndrome. Hum Reprod. 2006 Jan; 21(1):109-20. Cataldo NA, Abbasi F, McLaughlin TL, Basina M, Fechner PY, Giudice LC, Reaven GM. PMID: 16155076.
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    161. Decidual differentiation of stromal cells promotes Proprotein Convertase 5/6 expression and lefty processing. Endocrinology. 2005 Dec; 146(12):5313-20. Tang M, Mikhailik A, Pauli I, Giudice LC, Fazelabas AT, Tulac S, Carson DD, Kaufman DG, Barbier C, Creemers JW, Tabibzadeh S. PMID: 16141390.
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    162. Microbes on the human vaginal epithelium. Proc Natl Acad Sci U S A. 2005 May 31; 102(22):7952-7. Hyman RW, Fukushima M, Diamond L, Kumm J, Giudice LC, Davis RW. PMID: 15911771.
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    163. Natural killer cells in pregnancy and recurrent pregnancy loss: endocrine and immunologic perspectives. Endocr Rev. 2005 Feb; 26(1):44-62. Dosiou C, Giudice LC. PMID: 15689572.
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    164. Proteinase inhibition by proform of eosinophil major basic protein (pro-MBP) is a multistep process of intra- and intermolecular disulfide rearrangements. J Biol Chem. 2005 Mar 18; 280(11):9823-32. Glerup S, Boldt HB, Overgaard MT, Sottrup-Jensen L, Giudice LC, Oxvig C. PMID: 15647258.
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    165. Dose-dependent insulin regulation of insulin-like growth factor binding protein-1 in human endometrial stromal cells is mediated by distinct signaling pathways. J Clin Endocrinol Metab. 2005 Mar; 90(3):1599-606. Lathi RB, Hess AP, Tulac S, Nayak NR, Conti M, Giudice LC. PMID: 15613433.
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    166. Cellular expression and hormonal regulation of neuropilin-1 and -2 messenger ribonucleic Acid in the human and rhesus macaque endometrium. J Clin Endocrinol Metab. 2005 Mar; 90(3):1783-90. Germeyer A, Hamilton AE, Laughlin LS, Lasley BL, Brenner RM, Giudice LC, Nayak NR. PMID: 15613413.
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    167. Absence of secretory endometrium after false-positive home urine luteinizing hormone testing. Fertil Steril. 2004 Nov; 82(5):1273-7. McGovern PG, Myers ER, Silva S, Coutifaris C, Carson SA, Legro RS, Schlaff WD, Carr BR, Steinkampf MP, Giudice LC, Leppert PC, Diamond MP. PMID: 15533341.
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    170. Silencing lamin A/C in human endometrial stromal cells: a model to investigate endometrial gene function and regulation. Mol Hum Reprod. 2004 Oct; 10(10):705-11. Tulac S, Dosiou C, Suchanek E, Giudice LC. PMID: 15347737.
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    171. Developmental response to hypoxia. FASEB J. 2004 Sep; 18(12):1348-65. Huang ST, Vo KC, Lyell DJ, Faessen GH, Tulac S, Tibshirani R, Giaccia AJ, Giudice LC. PMID: 15333578.
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    172. The Lin12-notch repeats of pregnancy-associated plasma protein-A bind calcium and determine its proteolytic specificity. J Biol Chem. 2004 Sep 10; 279(37):38525-31. Boldt HB, Kjaer-Sorensen K, Overgaard MT, Weyer K, Poulsen CB, Sottrup-Jensen L, Conover CA, Giudice LC, Oxvig C. PMID: 15262980.
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    173. Interferon-related and other immune genes are downregulated in peripheral blood leukocytes in the luteal phase of the menstrual cycle. J Clin Endocrinol Metab. 2004 May; 89(5):2501-4. Dosiou C, Lathi RB, Tulac S, Huang ST, Giudice LC. PMID: 15126584.
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    174. Cell surface adhesion of pregnancy-associated plasma protein-A is mediated by four clusters of basic residues located in its third and fourth CCP module. Eur J Biochem. 2004 Apr; 271(8):1525-35. Weyer K, Overgaard MT, Laursen LS, Nielsen CG, Schmitz A, Christiansen M, Sottrup-Jensen L, Giudice LC, Oxvig C. PMID: 15066178.
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    175. Role of activin A as a mediator of in vitro endometrial stromal cell decidualization via the cyclic adenosine monophosphate pathway. Fertil Steril. 2004 Mar; 81 Suppl 1:899-903. Tierney EP, Giudice LC. PMID: 15019827.
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    176. Inhibition of proteolysis by the proform of eosinophil major basic protein (proMBP) requires covalent binding to its target proteinase. FEBS Lett. 2004 Feb 27; 560(1-3):147-52. Overgaard MT, Glerup S, Boldt HB, Rodacker V, Olsen IM, Christiansen M, Sottrup-Jensen L, Giudice LC, Oxvig C. PMID: 14988014.
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    177. Microarray expression profiling reveals candidate genes for human uterine receptivity. Am J Pharmacogenomics. 2004; 4(5):299-312. Giudice LC. PMID: 15462608.
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    180. Comparison of the sex ratio with blastocyst transfer and cleavage stage transfer. J Assist Reprod Genet. 2003 Aug; 20(8):323-6. Milki AA, Jun SH, Hinckley MD, Westphal LW, Giudice LC, Behr B. PMID: 12948095.
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    182. Prenatal screening, epidemiology, diagnosis, and management of preeclampsia. Clin Lab Med. 2003 Jun; 23(2):413-42. Lyell DJ, Lambert-Messerlian GM, Giudice LC. PMID: 12848452.
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    185. Comparative biology of the IGF system in endometrium, decidua, and placenta, and clinical implications for foetal growth and implantation disorders. Placenta. 2003 Apr; 24(4):281-96. Nayak NR, Giudice LC. PMID: 14626217.
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    186. Incidence of monozygotic twinning with blastocyst transfer compared to cleavage-stage transfer. Fertil Steril. 2003 Mar; 79(3):503-6. Milki AA, Jun SH, Hinckley MD, Behr B, Giudice LC, Westphal LM. PMID: 12620430.
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    187. Regulation of insulin-like growth factor-I and insulin-like growth factor binding protein-1 concentrations in preterm fetuses. Am J Obstet Gynecol. 2003 Feb; 188(2):485-91. Verhaeghe J, Van Herck E, Billen J, Moerman P, Van Assche FA, Giudice LC. PMID: 12592260.
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    188. Predictors of ovulatory failure in women with epilepsy. Ann Neurol. 2002 Dec; 52(6):704-11. Morrell MJ, Giudice L, Flynn KL, Seale CG, Paulson AJ, Doñe S, Flaster E, Ferin M, Sauer MV. PMID: 12447923.
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    189. Pregnancy-associated plasma protein A proteolytic activity is associated with the human placental trophoblast cell membrane. J Clin Endocrinol Metab. 2002 Nov; 87(11):5235-40. Sun IY, Overgaard MT, Oxvig C, Giudice LC. PMID: 12414897.
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    209. Ovarian follicular concentrations of activin, follistatin, inhibin, insulin-like growth factor I (IGF-I), IGF-II, IGF-binding protein-2 (IGFBP-2), IGFBP-3, and vascular endothelial growth factor in spontaneous menstrual cycles of normal women of advanced reproductive age. J Clin Endocrinol Metab. 2000 Dec; 85(12):4520-5. Klein NA, Battaglia DE, Woodruff TK, Padmanabhan V, Giudice LC, Bremner WJ, Soules MR. PMID: 11134102.
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    212. Regulation of insulin-like growth factor-binding protein-1 by nitric oxide under hypoxic conditions. J Clin Endocrinol Metab. 2000 Aug; 85(8):2714-21. Sugawara J, Suh DS, Faessen GH, Suen LF, Shibata T, Kaper F, Giaccia AJ, Giudice LC. PMID: 10946870.
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    213. Human placental trophoblasts secrete a disintegrin metalloproteinase very similar to the insulin-like growth factor binding protein-3 protease in human pregnancy serum. Endocrinology. 2000 Feb; 141(2):666-74. Irwin JC, Suen LF, Cheng BH, Martin R, Cannon P, Deal CL, Giudice LC. PMID: 10650948.
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    216. Role of the IGF system in trophoblast invasion and pre-eclampsia. Hum Reprod. 1999 Dec; 14 Suppl 2:90-6. Irwin JC, Suen LF, Martina NA, Mark SP, Giudice LC. PMID: 10690804.
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    221. Hypoxia and cAMP stimulate vascular endothelial growth factor (VEGF) in human endometrial stromal cells: potential relevance to menstruation and endometrial regeneration. J Clin Endocrinol Metab. 1999 Jun; 84(6):2245-8. Popovici RM, Irwin JC, Giaccia AJ, Giudice LC. PMID: 10372740.
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    223. Insulin-like growth factor-II mediates the steroidogenic and growth promoting actions of follicle stimulating hormone on human ovarian pre-antral follicles cultured in vitro. J Clin Endocrinol Metab. 1999 Apr; 84(4):1479-82. Yuan W, Giudice LC. PMID: 10199799.
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    224. Genes associated with embryonic attachment and implantation and the role of progesterone. J Reprod Med. 1999 Feb; 44(2 Suppl):165-71. Giudice LC. PMID: 11392027.
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    225. Roles of the insulinlike growth factor family in nonpregnant human endometrium and at the decidual: trophoblast interface. Semin Reprod Endocrinol. 1999; 17(1):13-21. Giudice LC, Irwin JC. PMID: 10406071.
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    232. Human granulosa cells use high density lipoprotein cholesterol for steroidogenesis. J Clin Endocrinol Metab. 1998 Mar; 83(3):983-91. Azhar S, Tsai L, Medicherla S, Chandrasekher Y, Giudice L, Reaven E. PMID: 9506760.
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    282. Local anesthesia with conscious sedation for laparoscopic intrafallopian transfer. Fertil Steril. 1992 Dec; 58(6):1240-2. Milki AA, Hardy RI, el Danasouri I, Giudice LC, Lamb EJ. PMID: 1459278.
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    283. Measurement and characterization of insulin-like growth factor binding protein-3 in human biological fluids: discrepancies between radioimmunoassay and ligand blotting. Endocrinology. 1992 Dec; 131(6):3051-60. Gargosky SE, Pham HM, Wilson KF, Liu F, Giudice LC, Rosenfeld RG. PMID: 1280211.
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    284. Insulin-like growth factors and ovarian follicular development. Endocr Rev. 1992 Nov; 13(4):641-69. Giudice LC. PMID: 1281087.
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    285. Steroid and peptide regulation of insulin-like growth factor-binding proteins secreted by human endometrial stromal cells is dependent on stromal differentiation. J Clin Endocrinol Metab. 1992 Nov; 75(5):1235-41. Giudice LC, Dsupin BA, Irwin JC. PMID: 1385468.
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    286. Prostate-specific antigen (PSA) is an insulin-like growth factor binding protein-3 protease found in seminal plasma. J Clin Endocrinol Metab. 1992 Oct; 75(4):1046-53. Cohen P, Graves HC, Peehl DM, Kamarei M, Giudice LC, Rosenfeld RG. PMID: 1383255.
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    287. Insulin-like growth factor binding protein profiles in human ovarian follicular fluid correlate with follicular functional status. J Clin Endocrinol Metab. 1992 Apr; 74(4):821-9. Cataldo NA, Giudice LC. PMID: 1372322.
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    288. Follicular fluid insulin-like growth factor binding protein profiles in polycystic ovary syndrome. J Clin Endocrinol Metab. 1992 Mar; 74(3):695-7. Cataldo NA, Giudice LC. PMID: 1371292.
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    289. Identification of insulin-like growth factor binding proteins in human oviduct. Fertil Steril. 1992 Feb; 57(2):294-301. Giudice LC, Dsupin BA, Irwin JC, Eckert RL. PMID: 1370941.
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    290. Maternal insulin-like growth factor-binding protein messenger ribonucleic acid during rat pregnancy. Endocrinology. 1991 Dec; 129(6):3359-66. Donovan SM, Giudice LC, Murphy LJ, Hintz RL, Rosenfeld RG. PMID: 1720094.
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    291. Human granulosa contain messenger ribonucleic acids encoding insulin-like growth factor-binding proteins (IGFBPs) and secrete IGFBPs in culture. Fertil Steril. 1991 Sep; 56(3):475-80. Giudice LC, Milki AA, Milkowski DA, el Danasouri I. PMID: 1716597.
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    292. A simple assay for proteolysis of IGFBP-3. J Clin Endocrinol Metab. 1991 Jun; 72(6):1391-3. Lamson G, Giudice LC, Rosenfeld RG. PMID: 1709177.
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    293. Characterization of the steroid-dependence of insulin-like growth factor-binding protein-2 synthesis and mRNA expression in cultured human endometrial stromal cells. Hum Reprod. 1991 May; 6(5):632-40. Giudice LC, Milkowski DA, Fielder PJ, Irwin JC. PMID: 1719019.
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    294. Insulin-like growth factor binding proteins in human endometrium: steroid-dependent messenger ribonucleic acid expression and protein synthesis. J Clin Endocrinol Metab. 1991 Apr; 72(4):779-87. Giudice LC, Milkowski DA, Lamson G, Rosenfeld RG, Irwin JC. PMID: 1706350.
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    295. Insulin-like growth factor-II (IGF-II) and IGF binding proteins in human endometrium. Ann N Y Acad Sci. 1991; 626:295-307. Giudice LC, Lamson G, Rosenfeld RG, Irwin JC. PMID: 1711826.
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    296. Insulin-like growth factor binding proteins: structural and molecular relationships. Growth Factors. 1991; 5(1):19-28. Lamson G, Giudice LC, Rosenfeld RG. PMID: 1722987.
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    297. Clinical aspects of insulin-like growth factor binding proteins. Acta Endocrinol (Copenh). 1991; 124 Suppl 2:74-85. Cohen P, Fielder PJ, Hasegawa Y, Frisch H, Giudice LC, Rosenfeld RG. PMID: 1713010.
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    298. Identification of insulin-like growth factor-binding protein-3 (IGFBP-3) and IGFBP-2 in human follicular fluid. J Clin Endocrinol Metab. 1990 Nov; 71(5):1330-8. Giudice LC, Farrell EM, Pham H, Rosenfeld RG. PMID: 1699963.
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    299. Insulin-like growth factor binding proteins in maternal serum throughout gestation and in the puerperium: effects of a pregnancy-associated serum protease activity. J Clin Endocrinol Metab. 1990 Oct; 71(4):806-16. Giudice LC, Farrell EM, Pham H, Lamson G, Rosenfeld RG. PMID: 1698200.
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    300. Identification of insulin-like growth factor-binding protein-2 (IGF-BP-2) and a low molecular weight IGF-BP in human seminal plasma. J Clin Endocrinol Metab. 1990 Feb; 70(2):551-3. Rosenfeld RG, Pham H, Oh Y, Lamson G, Giudice LC. PMID: 1688870.
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    301. Insulinlike growth factor-binding proteins. Recent Prog Horm Res. 1990; 46:99-159; discussion 159-63. Rosenfeld RG, Lamson G, Pham H, Oh Y, Conover C, De Leon DD, Donovan SM, Ocrant I, Giudice L. PMID: 1704143.
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    302. Expression of two insulin-like growth factor-binding proteins in a human endometrial cancer cell line: structural, immunological, and genetic characterization. J Clin Endocrinol Metab. 1989 Oct; 69(4):852-9. Lamson G, Oh Y, Pham H, Giudice LC, Rosenfeld RG. PMID: 2550507.
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    303. Cryopreservation of embryos and ova. Fertil Steril. 1988 May; 49(5):743-64. Friedler S, Giudice LC, Lamb EJ. PMID: 3282929.
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    304. Angiographic arterial embolization to control hemorrhage in abdominal pregnancy: a case report. Obstet Gynecol. 1988 Mar; 71(3 Pt 2):456-9. Kivikoski AI, Martin C, Weyman P, Picus D, Giudice L. PMID: 3347434.
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    305. Pregnancy following nonsurgical donor ovum transfer to a functionally agonadal woman. Fertil Steril. 1987 Aug; 48(2):324-5. Sauer MV, Macaso TM, Ishida EH, Giudice L, Marshall JR, Buster JE. PMID: 3609344.
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    306. Clinical results of Stanford University's in vitro fertilization and embryo transfer program. J In Vitro Fert Embryo Transf. 1987 Jun; 4(3):188-9. Lamb EJ, Polansky F, Milki A, Giudice LC, Friedler S, Wu T, Shen E, Turner K, Ho L. PMID: 3611930.
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    307. Serum levels of CA-125 in patients with endometriosis: a preliminary report. Fertil Steril. 1986 Jun; 45(6):876-8. Giudice LC, Jacobs A, Pineda J, Bell CE, Lippmann L. PMID: 3458595.
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    308. The function of the common subunit of glycoprotein hormones. Biochem Soc Trans. 1978; 6(1):57-60. Pierce JG, Bloomfield GA, Giudice LC. PMID: 640204.
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    309. Separation of functional and non-functional beta subunits of thyrotropin preparations by polyacrylamide gel electrophoresis. Endocrinology. 1977 Sep; 101(3):776-81. Giudice LC, Pierce JG. PMID: 408127.
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    310. Studies on the disulfide bonds of glycoprotein hormones. Course of reduction of bovine luteinizing hormone, bovine thyroid-stimulating hormone, and their subunits. J Biol Chem. 1976 Oct 25; 251(20):6388-91. Pierce JG, Giudice LC, Reeve JR. PMID: 988020.
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    311. Studies on the disulfide bonds of glycoprotein hormones. Complete reduction and reoxidation of the disulfide bonds of the alpha subunit of bovine luteinizing hormone. J Biol Chem. 1976 Oct 25; 251(20):6392-9. Giudice LC, Pierce JG. PMID: 988021.
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    312. Structure and structure-function relationships in glycoprotein hormones. Ciba Found Symp. 1976; 41:225-50. Pierce JG, Faith MR, Giudice LC, Reeve JR. PMID: 780075.
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