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Linda Giudice, MD, PhD

TitleProfessor
InstitutionUniversity of California San Francisco
DepartmentOb/Gyn, Reproductive Sciences
Address513 Parnassus Ave
San Francisco CA 94143
Phone415-502-2637
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    Other Positions
    TitleObstetrics, Gynecology and Reproductive Sciences


    Collapse Biography 
    Collapse Education and Training
    Stanford UniversityM.D.1982School of Medicine

    Collapse Overview 
    Collapse Overview
    Linda C. Giudice, MD, PhD is Distinguished Professor, Chair Emerita, and the Robert B. Jaffe MD Endowed Professor in the Reproductive Sciences in the Department of Obstetrics, Gynecology and Reproductive Sciences at the University of California, San Francisco (UCSF). She is a biochemist and reproductive endocrinologist specializing in endometriosis and infertility. Her research focuses on human endometrial function and regeneration, genetics and epigenetics of endometriosis, placental-uterine interactions relevant to pregnancy outcomes, and evaluating the evidence of environmental impacts on reproductive health and human development. She has mentored over 250 students, fellows and faculty, authored > 300 peer-reviewed publications, and is co-editor of 6 textbooks on women’s health, reproductive environmental health, endocrinology, endometrium and endometriosis. She is Past-President of the American Society for Reproductive Medicine, the Society for Gynecologic Investigation, President of the World Endometriosis Society, President-elect of the International Federation of Fertility Societies, and Chair of the FIGO (International Federation of Gynecology and Obstetrics) Reproductive and Developmental Environmental Health Working Group. Dr. Giudice is on the UCSF Steering Committee on Women’s Precision Medicine, the March of Dimes Scientific Advisory Council, and is an elected member of the U.S. National Academy of Medicine and the U.S. National Academy of Inventors.


    Collapse Research 
    Collapse Research Activities and Funding
    Integrative Analysis of Genomic, Epigenomic and Phenotypic Data for Disease Stratification of Endometriosis
    NIH/NICHD R01HD089511Sep 26, 2016 - Apr 30, 2021
    Role: Principal Investigator
    Exploring HIV-Host Interactions in the Female Reproductive Tract
    NIH/NIAID P01AI083050Sep 1, 2009 - Aug 31, 2014
    Role: Co-Principal Investigator
    Origins and Biological Consequences of Human Infertility
    NIH/NICHD P50HD055764May 3, 2007 - Mar 31, 2017
    Role: Principal Investigator
    Origins and Biological Consequences of Human Infertility
    NIH/NICHD U54HD055764May 3, 2007 - Mar 31, 2017
    Role: Principal Investigator
    Summit on Environmental Challenges to Reproductive Health and Fertility
    NIH/NIEHS R13ES015427Sep 15, 2006 - Aug 31, 2007
    Role: Principal Investigator
    Mentoring &Interdisciplinary Research in Women's Health
    NIH/NICHD K12HD043452Sep 27, 2002 - Dec 31, 2008
    Role: Co-Principal Investigator
    Gordon Research Conference on Reproductive Tract Biology
    NIH/NICHD R13HD042663Jun 19, 2002 - May 31, 2003
    Role: Principal Investigator
    Federally Registered Human Embryonic Stem Cell Center
    NIH/NCRR R24RR017498May 1, 2002 - Jul 31, 2007
    Role: Principal Investigator
    Role of IGF-II in Human Trophoblast-Decidua Interactions
    NIH/NICHD U01HD042298Apr 1, 2002 - Mar 31, 2008
    Role: Principal Investigator
    HYPOXIA, IGFBP-1, AND HUMAN FETAL GROWTH
    NIH/NICHD R01HD036732Mar 1, 2000 - Aug 31, 2004
    Role: Principal Investigator
    Women's Reproductive Health Research
    NIH/NICHD K12HD001262Sep 30, 1998 - Jun 30, 2020
    Role: Co-Principal Investigator
    Gonadal and Endometrial Function in Human Reproduction
    NIH/NICHD U54HD031398Apr 7, 1997 - Mar 31, 2008
    Role: Co-Principal Investigator
    ROLE OF IGF IN HUMAN OVARY
    NIH/NICHD R01HD031579May 1, 1994 - Sep 30, 2008
    Role: Principal Investigator
    INSULIN-LIKE GROWTH FACTOR SYSTEM IN OVIDUCT
    NIH/NICHD R03HD028079May 1, 1991 - Apr 30, 1993
    Role: Principal Investigator
    IGF BINDING PROTEINS AND HUMAN ENDOMETRIUM
    NIH/NICHD R01HD025220Apr 1, 1990 - Jul 31, 2002
    Role: Principal Investigator
    GENE EXPRESSION IN ENDOMETRIUM
    NIH/NICHD R29HD025220Apr 1, 1990 - Mar 31, 1996
    Role: Principal Investigator
    General Clinical Research Center
    NIH M01RR000070Dec 1, 1978 - Nov 30, 2011
    Role: Co-Investigator

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    Collapse Global Health
    Collapse Websites
    Collapse In The News

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Barnhart K, Giudice L, Young S, Thomas T, Diamond MP, Segars J, Youssef WA, Krawetz S, Santoro N, Eisenberg E, Zhang H. Evaluation, validation and refinement of noninvasive diagnostic biomarkers for endometriosis (ENDOmarker): A protocol to phenotype bio-specimens for discovery and validation. Contemp Clin Trials. 2018 Mar 07; 68:1-6. PMID: 29524590.
      View in: PubMed
    2. Martin JW, Chen JC, Neidleman J, Tatsumi K, Hu J, Giudice L, Greene WC, Roan NR. Potent and rapid activation of tropomyosin-receptor kinase A in endometrial stromal fibroblasts by seminal plasma. Biol Reprod. 2018 Mar 06. PMID: 29518187.
      View in: PubMed
    3. Aghajanova L, Houshdaran S, Balayan S, Manvelyan E, Irwin JC, Huddleston HG, Giudice L. In vitro evidence that platelet-rich plasma stimulates cellular processes involved in endometrial regeneration. J Assist Reprod Genet. 2018 Feb 05. PMID: 29404863.
      View in: PubMed
    4. Aghajanova L, Houshdaran S, Irwin JC, Giudice L. Effects of noncavity-distorting fibroids on endometrial gene expression and function. Biol Reprod. 2017 Oct 01; 97(4):564-576. PMID: 29025102.
      View in: PubMed
    5. Erikson DW, Barragan F, Piltonen TT, Chen JC, Balayan S, Irwin JC, Giudice L. Stromal fibroblasts from perimenopausal endometrium exhibit a different transcriptome than those from the premenopausal endometrium. Biol Reprod. 2017 Sep 01; 97(3):387-399. PMID: 29024986.
      View in: PubMed
    6. Altmäe S, Koel M, Võsa U, Adler P, Suhorutšenko M, Laisk-Podar T, Kukushkina V, Saare M, Velthut-Meikas A, Krjutškov K, Aghajanova L, Lalitkumar PG, Gemzell-Danielsson K, Giudice L, Simón C, Salumets A. Meta-signature of human endometrial receptivity: a meta-analysis and validation study of transcriptomic biomarkers. Sci Rep. 2017 Aug 30; 7(1):10077. PMID: 28855728.
      View in: PubMed
    7. Taylor HS, Giudice L, Lessey BA, Abrao MS, Kotarski J, Archer DF, Diamond MP, Surrey E, Johnson NP, Watts NB, Gallagher JC, Simon JA, Carr BR, Dmowski WP, Leyland N, Rowan JP, Duan WR, Ng J, Schwefel B, Thomas JW, Jain RI, Chwalisz K. Treatment of Endometriosis-Associated Pain with Elagolix, an Oral GnRH Antagonist. N Engl J Med. 2017 07 06; 377(1):28-40. PMID: 28525302.
      View in: PubMed
    8. Montgomery GW, Giudice L. New Lessons about Endometriosis - Somatic Mutations and Disease Heterogeneity. N Engl J Med. 2017 05 11; 376(19):1881-1882. PMID: 28489997.
      View in: PubMed
    9. Neidleman JA, Chen JC, Kohgadai N, Müller JA, Laustsen A, Thavachelvam K, Jang KS, Stürzel CM, Jones JJ, Ochsenbauer C, Chitre A, Somsouk M, Garcia MM, Smith JF, Greenblatt RM, Münch J, Jakobsen MR, Giudice L, Greene WC, Roan NR. Mucosal stromal fibroblasts markedly enhance HIV infection of CD4+ T cells. PLoS Pathog. 2017 Feb; 13(2):e1006163. PMID: 28207890.
      View in: PubMed
    10. Johnson NP, Hummelshoj L, Adamson GD, Keckstein J, Taylor HS, Abrao MS, Bush D, Kiesel L, Tamimi R, Sharpe-Timms KL, Rombauts L, Giudice L. World Endometriosis Society consensus on the classification of endometriosis. Hum Reprod. 2017 02; 32(2):315-324. PMID: 27920089.
      View in: PubMed
    11. Arora R, Fries A, Oelerich K, Marchuk K, Sabeur K, Giudice L, Laird DJ. Insights from imaging the implanting embryo and the uterine environment in three dimensions. Development. 2016 12 15; 143(24):4749-4754. PMID: 27836961.
      View in: PubMed
    12. Giudice L. Challenging dogma: the endometrium has a microbiome with functional consequences! Am J Obstet Gynecol. 2016 12; 215(6):682-683. PMID: 27725136.
      View in: PubMed
    13. Rogers PA, Adamson GD, Al-Jefout M, Becker CM, D'Hooghe TM, Dunselman GA, Fazleabas A, Giudice L, Horne AW, Hull ML, Hummelshoj L, Missmer SA, Montgomery GW, Stratton P, Taylor RN, Rombauts L, Saunders PT, Vincent K, Zondervan KT. Research Priorities for Endometriosis. Reprod Sci. 2017 02; 24(2):202-226. PMID: 27368878.
      View in: PubMed
    14. Giudice L. Environmental toxicants: hidden players on the reproductive stage. Fertil Steril. 2016 Sep 15; 106(4):791-4. PMID: 27545021.
      View in: PubMed
    15. Houshdaran S, Nezhat CR, Vo KC, Zelenko Z, Irwin JC, Giudice L. Aberrant Endometrial DNA Methylome and Associated Gene Expression in Women with Endometriosis. Biol Reprod. 2016 11; 95(5):93. PMID: 27535958.
      View in: PubMed
    16. Shanmugasundaram U, Hilton JF, Critchfield JW, Greenblatt RM, Giudice L, Averbach S, Seidman D, Shacklett BL, Smith-McCune K. Effects of the levonorgestrel-releasing intrauterine device on the immune microenvironment of the human cervix and endometrium. Am J Reprod Immunol. 2016 08; 76(2):137-48. PMID: 27401588.
      View in: PubMed
    17. Aghajanova L, Altmäe S, Kasvandik S, Salumets A, Stavreus-Evers A, Giudice L. Stanniocalcin-1 expression in normal human endometrium and dysregulation in endometriosis. Fertil Steril. 2016 Sep 01; 106(3):681-691.e1. PMID: 27322879; PMCID: PMC5010972 [Available on 09/01/17].
    18. Herndon CN, Aghajanova L, Balayan S, Erikson D, Barragan F, Goldfien G, Vo KC, Hawkins S, Giudice L. Global Transcriptome Abnormalities of the Eutopic Endometrium From Women With Adenomyosis. Reprod Sci. 2016 10; 23(10):1289-303. PMID: 27233751.
      View in: PubMed
    19. Sutton PM, Giudice L, Woodruff TJ. Moving from awareness to action on preventing patient exposure to toxic environmental chemicals. Am J Obstet Gynecol. 2016 05; 214(5):555-8. PMID: 27126615.
      View in: PubMed
    20. Barragan F, Irwin JC, Balayan S, Erikson DW, Chen JC, Houshdaran S, Piltonen TT, Spitzer TL, George A, Rabban JT, Nezhat C, Giudice L. Human Endometrial Fibroblasts Derived from Mesenchymal Progenitors Inherit Progesterone Resistance and Acquire an Inflammatory Phenotype in the Endometrial Niche in Endometriosis. Biol Reprod. 2016 05; 94(5):118. PMID: 27075616.
      View in: PubMed
    21. Chen JC, Hoffman JR, Arora R, Perrone LA, Gonzalez-Gomez CJ, Vo KC, Laird DJ, Irwin JC, Giudice L. Cryopreservation and recovery of human endometrial epithelial cells with high viability, purity, and functional fidelity. Fertil Steril. 2016 Feb; 105(2):501-10.e1. PMID: 26515378; PMCID: PMC4744114 [Available on 02/01/17].
    22. Di Renzo GC, Conry JA, Blake J, DeFrancesco MS, DeNicola N, Martin JN, McCue KA, Richmond D, Shah A, Sutton P, Woodruff TJ, van der Poel SZ, Giudice L. International Federation of Gynecology and Obstetrics opinion on reproductive health impacts of exposure to toxic environmental chemicals. Int J Gynaecol Obstet. 2015 Dec; 131(3):219-25. PMID: 26433469.
      View in: PubMed
    23. Vannuccini S, Clifton VL, Fraser IS, Taylor HS, Critchley H, Giudice L, Petraglia F. Infertility and reproductive disorders: impact of hormonal and inflammatory mechanisms on pregnancy outcome. Hum Reprod Update. 2016 Jan-Feb; 22(1):104-15. PMID: 26395640.
      View in: PubMed
    24. Bergman Å, Becher G, Blumberg B, Bjerregaard P, Bornman R, Brandt I, Casey SC, Frouin H, Giudice L, Heindel JJ, Iguchi T, Jobling S, Kidd KA, Kortenkamp A, Lind PM, Muir D, Ochieng R, Ropstad E, Ross PS, Skakkebaek NE, Toppari J, Vandenberg LN, Woodruff TJ, Zoeller RT. Manufacturing doubt about endocrine disrupter science--A rebuttal of industry-sponsored critical comments on the UNEP/WHO report "State of the Science of Endocrine Disrupting Chemicals 2012". Regul Toxicol Pharmacol. 2015 Dec; 73(3):1007-17. PMID: 26239693.
      View in: PubMed
    25. Smith-McCune K, Chen JC, Greenblatt RM, Shanmugasundaram U, Shacklett BL, Hilton JF, Johnson B, Irwin JC, Giudice L. Unexpected Inflammatory Effects of Intravaginal Gels (Universal Placebo Gel and Nonoxynol-9) on the Upper Female Reproductive Tract: A Randomized Crossover Study. PLoS One. 2015; 10(7):e0129769. PMID: 26177352; PMCID: PMC4503751.
    26. Fassbender A, Burney RO, O DF, D'Hooghe T, Giudice L. Update on Biomarkers for the Detection of Endometriosis. Biomed Res Int. 2015; 2015:130854. PMID: 26240814; PMCID: PMC4512573.
    27. Vercellini P, Giudice L, Evers JL, Abrao MS. Reducing low-value care in endometriosis between limited evidence and unresolved issues: a proposal. Hum Reprod. 2015 Sep; 30(9):1996-2004. PMID: 26141710.
      View in: PubMed
    28. Heard ME, Velarde MC, Giudice L, Simmen FA, Simmen RC. Krüppel-Like Factor 13 Deficiency in Uterine Endometrial Cells Contributes to Defective Steroid Hormone Receptor Signaling but Not Lesion Establishment in a Mouse Model of Endometriosis. Biol Reprod. 2015 Jun; 92(6):140. PMID: 25904015; PMCID: PMC4652611.
    29. Goldfien GA, Barragan F, Chen J, Takeda M, Irwin JC, Perry J, Greenblatt RM, Smith-McCune KK, Giudice L. Progestin-Containing Contraceptives Alter Expression of Host Defense-Related Genes of the Endometrium and Cervix. Reprod Sci. 2015 Jul; 22(7):814-28. PMID: 25634912; PMCID: PMC4565478.
    30. Williams KE, Miroshnychenko O, Johansen EB, Niles RK, Sundaram R, Kannan K, Albertolle M, Zhou Y, Prasad N, Drake PM, Giudice L, Hall SC, Witkowska HE, Buck Louis GM, Fisher SJ. Urine, peritoneal fluid and omental fat proteomes of reproductive age women: Endometriosis-related changes and associations with endocrine disrupting chemicals. J Proteomics. 2015 Jan 15; 113:194-205. PMID: 25284053; PMCID: PMC4467531.
    31. Rahmioglu N, Fassbender A, Vitonis AF, Tworoger SS, Hummelshoj L, D'Hooghe TM, Adamson GD, Giudice L, Becker CM, Zondervan KT, Missmer SA. World Endometriosis Research Foundation Endometriosis Phenome and Biobanking Harmonization Project: III. Fluid biospecimen collection, processing, and storage in endometriosis research. Fertil Steril. 2014 Nov; 102(5):1233-43. PMID: 25256929.
      View in: PubMed
    32. Vitonis AF, Vincent K, Rahmioglu N, Fassbender A, Buck Louis GM, Hummelshoj L, Giudice L, Stratton P, Adamson GD, Becker CM, Zondervan KT, Missmer SA. World Endometriosis Research Foundation Endometriosis Phenome and Biobanking Harmonization Project: II. Clinical and covariate phenotype data collection in endometriosis research. Fertil Steril. 2014 Nov; 102(5):1223-32. PMID: 25256930.
      View in: PubMed
    33. Tamaresis JS, Irwin JC, Goldfien GA, Rabban JT, Burney RO, Nezhat C, DePaolo LV, Giudice L. Molecular classification of endometriosis and disease stage using high-dimensional genomic data. Endocrinology. 2014 Dec; 155(12):4986-99. PMID: 25243856; PMCID: PMC4239429.
    34. Fassbender A, Rahmioglu N, Vitonis AF, Viganò P, Giudice L, D'Hooghe TM, Hummelshoj L, Adamson GD, Becker CM, Missmer SA, Zondervan KT. World Endometriosis Research Foundation Endometriosis Phenome and Biobanking Harmonisation Project: IV. Tissue collection, processing, and storage in endometriosis research. Fertil Steril. 2014 Nov; 102(5):1244-53. PMID: 25256928.
      View in: PubMed
    35. Houshdaran S, Zelenko Z, Irwin JC, Giudice L. Human endometrial DNA methylome is cycle-dependent and is associated with gene expression regulation. Mol Endocrinol. 2014 Jul; 28(7):1118-35. PMID: 24877562; PMCID: PMC4075160.
    36. Chen JC, Johnson BA, Erikson DW, Piltonen TT, Barragan F, Chu S, Kohgadai N, Irwin JC, Greene WC, Giudice L, Roan NR. Seminal plasma induces global transcriptomic changes associated with cell migration, proliferation and viability in endometrial epithelial cells and stromal fibroblasts. Hum Reprod. 2014 Jun; 29(6):1255-70. PMID: 24626806; PMCID: PMC4017943.
    37. Shanmugasundaram U, Critchfield JW, Pannell J, Perry J, Giudice L, Smith-McCune K, Greenblatt RM, Shacklett BL. Phenotype and functionality of CD4+ and CD8+ T cells in the upper reproductive tract of healthy premenopausal women. Am J Reprod Immunol. 2014 Feb; 71(2):95-108. PMID: 24313954; PMCID: PMC3947236.
    38. Altmäe S, Esteban FJ, Stavreus-Evers A, Simón C, Giudice L, Lessey BA, Horcajadas JA, Macklon NS, D'Hooghe T, Campoy C, Fauser BC, Salamonsen LA, Salumets A. Guidelines for the design, analysis and interpretation of 'omics' data: focus on human endometrium. Hum Reprod Update. 2014 Jan-Feb; 20(1):12-28. PMID: 24082038; PMCID: PMC3845681.
    39. Bergman Å, Andersson AM, Becher G, van den Berg M, Blumberg B, Bjerregaard P, Bornehag CG, Bornman R, Brandt I, Brian JV, Casey SC, Fowler PA, Frouin H, Giudice L, Iguchi T, Hass U, Jobling S, Juul A, Kidd KA, Kortenkamp A, Lind M, Martin OV, Muir D, Ochieng R, Olea N, Norrgren L, Ropstad E, Ross PS, Rudén C, Scheringer M, Skakkebaek NE, Söder O, Sonnenschein C, Soto A, Swan S, Toppari J, Tyler CR, Vandenberg LN, Vinggaard AM, Wiberg K, Zoeller RT. Science and policy on endocrine disrupters must not be mixed: a reply to a "common sense" intervention by toxicology journal editors. Environ Health. 2013 Aug 27; 12:69. PMID: 23981490; PMCID: PMC3765603.
    40. Chen JC, Erikson DW, Piltonen TT, Meyer MR, Barragan F, McIntire RH, Tamaresis JS, Vo KC, Giudice L, Irwin JC. Coculturing human endometrial epithelial cells and stromal fibroblasts alters cell-specific gene expression and cytokine production. Fertil Steril. 2013 Oct; 100(4):1132-43. PMID: 23849844.
      View in: PubMed
    41. Hyman RW, Fukushima M, Jiang H, Fung E, Rand L, Johnson B, Vo KC, Caughey AB, Hilton JF, Davis RW, Giudice L. Diversity of the vaginal microbiome correlates with preterm birth. Reprod Sci. 2014 Jan; 21(1):32-40. PMID: 23715799; PMCID: PMC3857766.
    42. Fisher SJ, Giudice L. Retrospective. Robert G. Edwards (1925-2013). Science. 2013 May 17; 340(6134):825. PMID: 23687039.
      View in: PubMed
    43. Buck Louis GM, Peterson CM, Chen Z, Croughan M, Sundaram R, Stanford J, Varner MW, Kennedy A, Giudice L, Fujimoto VY, Sun L, Wang L, Guo Y, Kannan K. Bisphenol A and phthalates and endometriosis: the Endometriosis: Natural History, Diagnosis and Outcomes Study. Fertil Steril. 2013 Jul; 100(1):162-9.e1-2. PMID: 23579005.
      View in: PubMed
    44. Rogers PA, D'Hooghe TM, Fazleabas A, Giudice L, Montgomery GW, Petraglia F, Taylor RN. Defining future directions for endometriosis research: workshop report from the 2011 World Congress of Endometriosis In Montpellier, France. Reprod Sci. 2013 May; 20(5):483-99. PMID: 23427182; PMCID: PMC3635070.
    45. Louis GM, Peterson CM, Chen Z, Hediger ML, Croughan MS, Sundaram R, Stanford JB, Fujimoto VY, Varner MW, Giudice L, Kennedy A, Sun L, Wu Q, Kannan K. Perfluorochemicals and endometriosis: the ENDO study. Epidemiology. 2012 Nov; 23(6):799-805. PMID: 22992575.
      View in: PubMed
    46. Meldrum DR, Chang RJ, Giudice L, Balasch J, Barbieri RL. Role of decreased androgens in the ovarian response to stimulation in older women. Fertil Steril. 2013 Jan; 99(1):5-11. PMID: 23122826.
      View in: PubMed
    47. Burney RO, Giudice L. Pathogenesis and pathophysiology of endometriosis. Fertil Steril. 2012 Sep; 98(3):511-9. PMID: 22819144; PMCID: PMC3836682.
    48. Buck Louis GM, Chen Z, Peterson CM, Hediger ML, Croughan MS, Sundaram R, Stanford JB, Varner MW, Fujimoto VY, Giudice L, Trumble A, Parsons PJ, Kannan K. Persistent lipophilic environmental chemicals and endometriosis: the ENDO Study. Environ Health Perspect. 2012 Jun; 120(6):811-6. PMID: 22417635; PMCID: PMC3385438.
    49. Hyman RW, St Onge RP, Kim H, Tamaresis JS, Miranda M, Aparicio AM, Fukushima M, Pourmand N, Giudice L, Davis RW. Molecular probe technology detects bacteria without culture. BMC Microbiol. 2012 Mar 09; 12:29. PMID: 22404909; PMCID: PMC3316761.
    50. Sutton P, Woodruff TJ, Perron J, Stotland N, Conry JA, Miller MD, Giudice L. Toxic environmental chemicals: the role of reproductive health professionals in preventing harmful exposures. Am J Obstet Gynecol. 2012 Sep; 207(3):164-73. PMID: 22405527.
      View in: PubMed
    51. Spitzer TL, Rojas A, Zelenko Z, Aghajanova L, Erikson DW, Barragan F, Meyer M, Tamaresis JS, Hamilton AE, Irwin JC, Giudice L. Perivascular human endometrial mesenchymal stem cells express pathways relevant to self-renewal, lineage specification, and functional phenotype. Biol Reprod. 2012 Feb; 86(2):58. PMID: 22075475; PMCID: PMC3290674.
    52. Pabona JM, Simmen FA, Nikiforov MA, Zhuang D, Shankar K, Velarde MC, Zelenko Z, Giudice L, Simmen RC. Krüppel-like factor 9 and progesterone receptor coregulation of decidualizing endometrial stromal cells: implications for the pathogenesis of endometriosis. J Clin Endocrinol Metab. 2012 Mar; 97(3):E376-92. PMID: 22259059; PMCID: PMC3319212.
    53. Aghajanova L, Shen S, Rojas AM, Fisher SJ, Irwin JC, Giudice L. Comparative transcriptome analysis of human trophectoderm and embryonic stem cell-derived trophoblasts reveal key participants in early implantation. Biol Reprod. 2012 Jan; 86(1):1-21. PMID: 21865555.
      View in: PubMed
    54. Hyman RW, Herndon CN, Jiang H, Palm C, Fukushima M, Bernstein D, Vo KC, Zelenko Z, Davis RW, Giudice L. The dynamics of the vaginal microbiome during infertility therapy with in vitro fertilization-embryo transfer. J Assist Reprod Genet. 2012 Feb; 29(2):105-15. PMID: 22222853; PMCID: PMC3270134.
    55. Leach RE, Jessmon P, Coutifaris C, Kruger M, Myers ER, Ali-Fehmi R, Carson SA, Legro RS, Schlaff WD, Carr BR, Steinkampf MP, Silva S, Leppert PC, Giudice L, Diamond MP, Armant DR. High throughput, cell type-specific analysis of key proteins in human endometrial biopsies of women from fertile and infertile couples. Hum Reprod. 2012 Mar; 27(3):814-28. PMID: 22215622; PMCID: PMC3279126.
    56. Zelenko Z, Aghajanova L, Irwin JC, Giudice L. Nuclear receptor, coregulator signaling, and chromatin remodeling pathways suggest involvement of the epigenome in the steroid hormone response of endometrium and abnormalities in endometriosis. Reprod Sci. 2012 Feb; 19(2):152-62. PMID: 22138541; PMCID: PMC3343132.
    57. White WB, Grady D, Giudice L, Berry SM, Zborowski J, Snabes MC. A cardiovascular safety study of LibiGel (testosterone gel) in postmenopausal women with elevated cardiovascular risk and hypoactive sexual desire disorder. Am Heart J. 2012 Jan; 163(1):27-32. PMID: 22172433.
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    58. Fisher SJ, Giudice L. SGK1: a fine balancing act for human pregnancy. Nat Med. 2011 Nov 07; 17(11):1348-9. PMID: 22064410.
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    59. Buck Louis GM, Hediger ML, Peterson CM, Croughan M, Sundaram R, Stanford J, Chen Z, Fujimoto VY, Varner MW, Trumble A, Giudice L. Incidence of endometriosis by study population and diagnostic method: the ENDO study. Fertil Steril. 2011 Aug; 96(2):360-5. PMID: 21719000.
      View in: PubMed
    60. Savaris RF, Groll JM, Young SL, DeMayo FJ, Jeong JW, Hamilton AE, Giudice L, Lessey BA. Progesterone resistance in PCOS endometrium: a microarray analysis in clomiphene citrate-treated and artificial menstrual cycles. J Clin Endocrinol Metab. 2011 Jun; 96(6):1737-46. PMID: 21411543; PMCID: PMC3100753.
    61. Marchand M, Horcajadas JA, Esteban FJ, McElroy SL, Fisher SJ, Giudice L. Transcriptomic signature of trophoblast differentiation in a human embryonic stem cell model. Biol Reprod. 2011 Jun; 84(6):1258-71. PMID: 21368299.
      View in: PubMed
    62. Sheldon E, Vo KC, McIntire RA, Aghajanova L, Zelenko Z, Irwin JC, Giudice L. Biobanking human endometrial tissue and blood specimens: standard operating procedure and importance to reproductive biology research and diagnostic development. Fertil Steril. 2011 May; 95(6):2120-2, 2122.e1-12. PMID: 21371706; PMCID: PMC3080464.
    63. Sutton P, Giudice L, Woodruff TJ. Reproductive environmental health. Curr Opin Obstet Gynecol. 2010 Dec; 22(6):517-24. PMID: 20978443.
      View in: PubMed
    64. Aghajanova L, Giudice L. Molecular evidence for differences in endometrium in severe versus mild endometriosis. Reprod Sci. 2011 Mar; 18(3):229-51. PMID: 21063030; PMCID: PMC3118406.
    65. Salamonsen LA, Giudice L. "The curse": a 21st century perspective of models of its molecular basis. Endocrinology. 2010 Sep; 151(9):4092-5. PMID: 20736404.
      View in: PubMed
    66. Giudice L. Clinical practice. Endometriosis. N Engl J Med. 2010 Jun 24; 362(25):2389-98. PMID: 20573927; PMCID: PMC3108065.
    67. Jacoby VL, Fujimoto VY, Giudice L, Kuppermann M, Washington AE. Racial and ethnic disparities in benign gynecologic conditions and associated surgeries. Am J Obstet Gynecol. 2010 Jun; 202(6):514-21. PMID: 20430357; PMCID: PMC4625911.
    68. Woodruff TJ, Schwartz J, Giudice L. Research agenda for environmental reproductive health in the 21st century. J Epidemiol Community Health. 2010 Apr; 64(4):307-10. PMID: 20348330.
      View in: PubMed
    69. Huddleston HG, Cedars MI, Sohn SH, Giudice L, Fujimoto VY. Racial and ethnic disparities in reproductive endocrinology and infertility. Am J Obstet Gynecol. 2010 May; 202(5):413-9. PMID: 20207341.
      View in: PubMed
    70. Lo B, Parham L, Cedars M, Fisher S, Gates E, Giudice L, Halme DG, Hershon W, Kriegstein A, Rao R, Roberts C, Wagner R. Research ethics. NIH guidelines for stem cell research and gamete donors. Science. 2010 Feb 19; 327(5968):962-3. PMID: 20167773; PMCID: PMC2892655.
    71. Aghajanova L, Horcajadas JA, Esteban FJ, Giudice L. The bone marrow-derived human mesenchymal stem cell: potential progenitor of the endometrial stromal fibroblast. Biol Reprod. 2010 Jun; 82(6):1076-87. PMID: 20147733; PMCID: PMC2874495.
    72. Nyegaard M, Overgaard MT, Su YQ, Hamilton AE, Kwintkiewicz J, Hsieh M, Nayak NR, Conti M, Conover CA, Giudice L. Lack of functional pregnancy-associated plasma protein-A (PAPPA) compromises mouse ovarian steroidogenesis and female fertility. Biol Reprod. 2010 Jun; 82(6):1129-38. PMID: 20130263; PMCID: PMC2874498.
    73. Aghajanova L, Velarde MC, Giudice L. Altered gene expression profiling in endometrium: evidence for progesterone resistance. Semin Reprod Med. 2010 Jan; 28(1):51-8. PMID: 20104428.
      View in: PubMed
    74. Aghajanova L, Horcajadas JA, Weeks JL, Esteban FJ, Nezhat CN, Conti M, Giudice L. The protein kinase A pathway-regulated transcriptome of endometrial stromal fibroblasts reveals compromised differentiation and persistent proliferative potential in endometriosis. Endocrinology. 2010 Mar; 151(3):1341-55. PMID: 20068008; PMCID: PMC2840687.
    75. Lo B, Parham L, Alvarez-Buylla A, Cedars M, Conklin B, Fisher S, Gates E, Giudice L, Halme DG, Hershon W, Kriegstein A, Kwok PY, Wagner R. Cloning mice and men: prohibiting the use of iPS cells for human reproductive cloning. Cell Stem Cell. 2010 Jan 08; 6(1):16-20. PMID: 20085739; PMCID: PMC4035242.
    76. Van Vaerenbergh I, McIntire R, Van Lommel L, Devroey P, Giudice L, Bourgain C. Gene expression during successful implantation in a natural cycle. Fertil Steril. 2010 Jan; 93(1):268.e15-8. PMID: 19880110; PMCID: PMC2812655.
    77. Kwintkiewicz J, Nishi Y, Yanase T, Giudice L. Peroxisome proliferator-activated receptor-gamma mediates bisphenol A inhibition of FSH-stimulated IGF-1, aromatase, and estradiol in human granulosa cells. Environ Health Perspect. 2010 Mar; 118(3):400-6. PMID: 20064783; PMCID: PMC2854770.
    78. Burney RO, Hamilton AE, Aghajanova L, Vo KC, Nezhat CN, Lessey BA, Giudice L. MicroRNA expression profiling of eutopic secretory endometrium in women with versus without endometriosis. Mol Hum Reprod. 2009 Oct; 15(10):625-31. PMID: 19692421; PMCID: PMC2744474.
    79. Velarde MC, Aghajanova L, Nezhat CR, Giudice L. Increased mitogen-activated protein kinase kinase/extracellularly regulated kinase activity in human endometrial stromal fibroblasts of women with endometriosis reduces 3',5'-cyclic adenosine 5'-monophosphate inhibition of cyclin D1. Endocrinology. 2009 Oct; 150(10):4701-12. PMID: 19589865; PMCID: PMC2754675.
    80. Pagidas K, Carson SA, McGovern PG, Barnhart HX, Myers ER, Legro RS, Diamond MP, Carr BR, Schlaff WD, Coutifaris C, Steinkampf MP, Cataldo NA, Nestler JE, Gosman G, Giudice L. Body mass index and intercourse compliance. Fertil Steril. 2010 Sep; 94(4):1447-50. PMID: 19540480; PMCID: PMC3708655.
    81. Pagidas K, Carson SA, McGovern PG, Barnhart HX, Myers ER, Legro RS, Diamond MP, Carr BR, Schlaff WD, Coutifaris C, Steinkampf MP, Cataldo NA, Nestler JE, Gosman G, Giudice L. Intercourse compliance, ovulation, and treatment success in the National Institute of Child Health and Human Development-Reproductive Medicine Network's Pregnancy in Polycystic Ovary Syndrome (PPCOS) Trial. Fertil Steril. 2010 Sep; 94(4):1444-6. PMID: 19540477; PMCID: PMC2891817.
    82. Rausch ME, Legro RS, Barnhart HX, Schlaff WD, Carr BR, Diamond MP, Carson SA, Steinkampf MP, McGovern PG, Cataldo NA, Gosman GG, Nestler JE, Giudice L, Leppert PC, Myers ER, Coutifaris C. Predictors of pregnancy in women with polycystic ovary syndrome. J Clin Endocrinol Metab. 2009 Sep; 94(9):3458-66. PMID: 19509098; PMCID: PMC2741722.
    83. Diamanti-Kandarakis E, Bourguignon JP, Giudice L, Hauser R, Prins GS, Soto AM, Zoeller RT, Gore AC. Endocrine-disrupting chemicals: an Endocrine Society scientific statement. Endocr Rev. 2009 Jun; 30(4):293-342. PMID: 19502515; PMCID: PMC2726844.
    84. Jeong JW, Lee HS, Lee KY, White LD, Broaddus RR, Zhang YW, Vande Woude GF, Giudice L, Young SL, Lessey BA, Tsai SY, Lydon JP, DeMayo FJ. Mig-6 modulates uterine steroid hormone responsiveness and exhibits altered expression in endometrial disease. Proc Natl Acad Sci U S A. 2009 May 26; 106(21):8677-82. PMID: 19439667; PMCID: PMC2681319.
    85. Robertson RP, Giudice L. Editorial: Update on stem cell research. Endocr Rev. 2009 May; 30(3):203. PMID: 19433633.
      View in: PubMed
    86. Aghajanova L, Velarde MC, Giudice L. The progesterone receptor coactivator Hic-5 is involved in the pathophysiology of endometriosis. Endocrinology. 2009 Aug; 150(8):3863-70. PMID: 19389829; PMCID: PMC2717860.
    87. Lo B, Parham L, Broom C, Cedars M, Gates E, Giudice L, Halme DG, Hershon W, Kriegstein A, Kwok PY, Oberman M, Roberts C, Wagner R. Importing human pluripotent stem cell lines derived at another institution: tailoring review to ethical concerns. Cell Stem Cell. 2009 Feb 06; 4(2):115-23. PMID: 19200800.
      View in: PubMed
    88. Kwintkiewicz J, Giudice L. The interplay of insulin-like growth factors, gonadotropins, and endocrine disruptors in ovarian follicular development and function. Semin Reprod Med. 2009 Jan; 27(1):43-51. PMID: 19197804.
      View in: PubMed
    89. Rogers PA, D'Hooghe TM, Fazleabas A, Gargett CE, Giudice L, Montgomery GW, Rombauts L, Salamonsen LA, Zondervan KT. Priorities for endometriosis research: recommendations from an international consensus workshop. Reprod Sci. 2009 Apr; 16(4):335-46. PMID: 19196878.
      View in: PubMed
    90. Savaris RF, Giudice L. Genomics analysis: endometrium. Methods Mol Biol. 2009; 590:91-113. PMID: 19763499.
      View in: PubMed
    91. Conti M, Giudice L. From stem cells to germ cells and back again. Nat Med. 2008 Nov; 14(11):1188-90. PMID: 18989302.
      View in: PubMed
    92. Crain DA, Janssen SJ, Edwards TM, Heindel J, Ho SM, Hunt P, Iguchi T, Juul A, McLachlan JA, Schwartz J, Skakkebaek N, Soto AM, Swan S, Walker C, Woodruff TK, Woodruff TJ, Giudice L, Guillette LJ. Female reproductive disorders: the roles of endocrine-disrupting compounds and developmental timing. Fertil Steril. 2008 Oct; 90(4):911-40. PMID: 18929049; PMCID: PMC4086418.
    93. Aghajanova L, Hamilton A, Kwintkiewicz J, Vo KC, Giudice L. Steroidogenic enzyme and key decidualization marker dysregulation in endometrial stromal cells from women with versus without endometriosis. Biol Reprod. 2009 Jan; 80(1):105-14. PMID: 18815356; PMCID: PMC2704986.
    94. Stillerman KP, Mattison DR, Giudice L, Woodruff TJ. Environmental exposures and adverse pregnancy outcomes: a review of the science. Reprod Sci. 2008 Sep; 15(7):631-50. PMID: 18836129.
      View in: PubMed
    95. Horcajadas JA, Mínguez P, Dopazo J, Esteban FJ, Domínguez F, Giudice L, Pellicer A, Simón C. Controlled ovarian stimulation induces a functional genomic delay of the endometrium with potential clinical implications. J Clin Endocrinol Metab. 2008 Nov; 93(11):4500-10. PMID: 18697870.
      View in: PubMed
    96. Fan X, Krieg S, Kuo CJ, Wiegand SJ, Rabinovitch M, Druzin ML, Brenner RM, Giudice L, Nayak NR. VEGF blockade inhibits angiogenesis and reepithelialization of endometrium. FASEB J. 2008 Oct; 22(10):3571-80. PMID: 18606863; PMCID: PMC2537439.
    97. Savaris RF, Hamilton AE, Lessey BA, Giudice L. Endometrial gene expression in early pregnancy: lessons from human ectopic pregnancy. Reprod Sci. 2008 Oct; 15(8):797-816. PMID: 18591649; PMCID: PMC2882188.
    98. Cataldo NA, Barnhart HX, Legro RS, Myers ER, Schlaff WD, Carr BR, Diamond MP, Carson SA, Steinkampf MP, Coutifaris C, McGovern PG, Gosman G, Nestler JE, Giudice L. Extended-release metformin does not reduce the clomiphene citrate dose required to induce ovulation in polycystic ovary syndrome. J Clin Endocrinol Metab. 2008 Aug; 93(8):3124-7. PMID: 18505764; PMCID: PMC2515084.
    99. McElroy SL, Kee K, Tran N, Menses J, Giudice L, Reijo Pera RA. Developmental competence of immature and failed/abnormally fertilized human oocytes in nuclear transfer. Reprod Biomed Online. 2008 May; 16(5):684-93. PMID: 18492373.
      View in: PubMed
    100. Macklon NS, van der Gaast MH, Hamilton A, Fauser BC, Giudice L. The impact of ovarian stimulation with recombinant FSH in combination with GnRH antagonist on the endometrial transcriptome in the window of implantation. Reprod Sci. 2008 Apr; 15(4):357-65. PMID: 18497344.
      View in: PubMed
    101. Woodruff TJ, Carlson A, Schwartz JM, Giudice L. Proceedings of the Summit on Environmental Challenges to Reproductive Health and Fertility: executive summary. Fertil Steril. 2008 Feb; 89(2):281-300. PMID: 18275883; PMCID: PMC2440710.
    102. Woodruff TJ, Carlson A, Schwartz JM, Giudice L. Proceedings of the Summit on Environmental Challenges to Reproductive Health and Fertility: executive summary. Fertil Steril. 2008 Feb; 89(2 Suppl):e1-e20. PMID: 18308046.
      View in: PubMed
    103. McGovern PG, Carson SA, Barnhart HX, Myers ER, Legro RS, Diamond MP, Carr BR, Schlaff WD, Coutifaris C, Cataldo NA, Steinkampf MP, Nestler JE, Gosman G, Leppert PC, Giudice L. Medication adherence and treatment success in the National Institute of Child Health and Human Development-Reproductive Medicine Network's Pregnancy in Polycystic Ovary Syndrome Trial. Fertil Steril. 2008 Oct; 90(4):1283-6. PMID: 18082737; PMCID: PMC2570771.
    104. Legro RS, Barnhart HX, Schlaff WD, Carr BR, Diamond MP, Carson SA, Steinkampf MP, Coutifaris C, McGovern PG, Cataldo NA, Gosman GG, Nestler JE, Giudice L, Ewens KG, Spielman RS, Leppert PC, Myers ER. Ovulatory response to treatment of polycystic ovary syndrome is associated with a polymorphism in the STK11 gene. J Clin Endocrinol Metab. 2008 Mar; 93(3):792-800. PMID: 18000088; PMCID: PMC2266955.
    105. Savaris RF, Giudice L. The influence of hydrosalpinx on markers of endometrial receptivity. Semin Reprod Med. 2007 Nov; 25(6):476-82. PMID: 17960532.
      View in: PubMed
    106. Burney RO, Talbi S, Hamilton AE, Vo KC, Nyegaard M, Nezhat CR, Lessey BA, Giudice L. Gene expression analysis of endometrium reveals progesterone resistance and candidate susceptibility genes in women with endometriosis. Endocrinology. 2007 Aug; 148(8):3814-26. PMID: 17510236.
      View in: PubMed
    107. Legro RS, Barnhart HX, Schlaff WD, Carr BR, Diamond MP, Carson SA, Steinkampf MP, Coutifaris C, McGovern PG, Cataldo NA, Gosman GG, Nestler JE, Giudice L, Leppert PC, Myers ER. Clomiphene, metformin, or both for infertility in the polycystic ovary syndrome. N Engl J Med. 2007 Feb 08; 356(6):551-66. PMID: 17287476.
      View in: PubMed
    108. McGovern PG, Legro RS, Myers ER, Barnhart HX, Carson SA, Diamond MP, Carr BR, Schlaff WD, Coutifaris C, Steinkampf MP, Nestler JE, Gosman G, Leppert PC, Giudice L. Utility of screening for other causes of infertility in women with "known" polycystic ovary syndrome. Fertil Steril. 2007 Feb; 87(2):442-4. PMID: 17141768; PMCID: PMC1813322.
    109. Red-Horse K, Rivera J, Schanz A, Zhou Y, Winn V, Kapidzic M, Maltepe E, Okazaki K, Kochman R, Vo KC, Giudice L, Erlebacher A, McCune JM, Stoddart CA, Fisher SJ. Cytotrophoblast induction of arterial apoptosis and lymphangiogenesis in an in vivo model of human placentation. J Clin Invest. 2006 Oct; 116(10):2643-52. PMID: 16998586; PMCID: PMC1570373.
    110. Su YQ, Nyegaard M, Overgaard MT, Qiao J, Giudice L. Participation of mitogen-activated protein kinase in luteinizing hormone-induced differential regulation of steroidogenesis and steroidogenic gene expression in mural and cumulus granulosa cells of mouse preovulatory follicles. Biol Reprod. 2006 Dec; 75(6):859-67. PMID: 16943367.
      View in: PubMed
    111. Giudice L. Infertility and the environment: the medical context. Semin Reprod Med. 2006 Jul; 24(3):129-33. PMID: 16804810.
      View in: PubMed
    112. Legro RS, Azziz R, Giudice L. A twenty-first century research agenda for polycystic ovary syndrome. Best Pract Res Clin Endocrinol Metab. 2006 Jun; 20(2):331-6. PMID: 16772161.
      View in: PubMed
    113. Giudice L. Endometrium in PCOS: Implantation and predisposition to endocrine CA. Best Pract Res Clin Endocrinol Metab. 2006 Jun; 20(2):235-44. PMID: 16772154.
      View in: PubMed
    114. Tulac S, Overgaard MT, Hamilton AE, Jumbe NL, Suchanek E, Giudice L. Dickkopf-1, an inhibitor of Wnt signaling, is regulated by progesterone in human endometrial stromal cells. J Clin Endocrinol Metab. 2006 Apr; 91(4):1453-61. PMID: 16449346.
      View in: PubMed
    115. Macklon NS, Stouffer RL, Giudice L, Fauser BC. The science behind 25 years of ovarian stimulation for in vitro fertilization. Endocr Rev. 2006 Apr; 27(2):170-207. PMID: 16434510.
      View in: PubMed
    116. Nayak NR, Kuo CJ, Desai TA, Wiegand SJ, Lasley BL, Giudice L, Brenner RM. Expression, localization and hormonal control of angiopoietin-1 in the rhesus macaque endometrium: potential role in spiral artery growth. Mol Hum Reprod. 2005 Nov; 11(11):791-9. PMID: 16390855.
      View in: PubMed
    117. Giudice L. Application of functional genomics to primate endometrium: insights into biological processes. Reprod Biol Endocrinol. 2006; 4 Suppl 1:S4. PMID: 17118168; PMCID: PMC1775064.
    118. Littman E, Giudice L, Lathi R, Berker B, Milki A, Nezhat C. Role of laparoscopic treatment of endometriosis in patients with failed in vitro fertilization cycles. Fertil Steril. 2005 Dec; 84(6):1574-8. PMID: 16359945.
      View in: PubMed
    119. Nezhat C, Littman ED, Lathi RB, Berker B, Westphal LM, Giudice L, Milki AA. The dilemma of endometriosis: is consensus possible with an enigma? Fertil Steril. 2005 Dec; 84(6):1587-8. PMID: 16359950.
      View in: PubMed
    120. Li T, Vu TH, Ulaner GA, Littman E, Ling JQ, Chen HL, Hu JF, Behr B, Giudice L, Hoffman AR. IVF results in de novo DNA methylation and histone methylation at an Igf2-H19 imprinting epigenetic switch. Mol Hum Reprod. 2005 Sep; 11(9):631-40. PMID: 16219628.
      View in: PubMed
    121. Cataldo NA, Abbasi F, McLaughlin TL, Basina M, Fechner PY, Giudice L, Reaven GM. Metabolic and ovarian effects of rosiglitazone treatment for 12 weeks in insulin-resistant women with polycystic ovary syndrome. Hum Reprod. 2006 Jan; 21(1):109-20. PMID: 16155076.
      View in: PubMed
    122. Tang M, Mikhailik A, Pauli I, Giudice L, Fazelabas AT, Tulac S, Carson DD, Kaufman DG, Barbier C, Creemers JW, Tabibzadeh S. Decidual differentiation of stromal cells promotes Proprotein Convertase 5/6 expression and lefty processing. Endocrinology. 2005 Dec; 146(12):5313-20. PMID: 16141390.
      View in: PubMed
    123. Hyman RW, Fukushima M, Diamond L, Kumm J, Giudice L, Davis RW. Microbes on the human vaginal epithelium. Proc Natl Acad Sci U S A. 2005 May 31; 102(22):7952-7. PMID: 15911771; PMCID: PMC1142396.
    124. Dosiou C, Giudice L. Natural killer cells in pregnancy and recurrent pregnancy loss: endocrine and immunologic perspectives. Endocr Rev. 2005 Feb; 26(1):44-62. PMID: 15689572.
      View in: PubMed
    125. Glerup S, Boldt HB, Overgaard MT, Sottrup-Jensen L, Giudice L, Oxvig C. Proteinase inhibition by proform of eosinophil major basic protein (pro-MBP) is a multistep process of intra- and intermolecular disulfide rearrangements. J Biol Chem. 2005 Mar 18; 280(11):9823-32. PMID: 15647258.
      View in: PubMed
    126. Germeyer A, Hamilton AE, Laughlin LS, Lasley BL, Brenner RM, Giudice L, Nayak NR. Cellular expression and hormonal regulation of neuropilin-1 and -2 messenger ribonucleic Acid in the human and rhesus macaque endometrium. J Clin Endocrinol Metab. 2005 Mar; 90(3):1783-90. PMID: 15613413.
      View in: PubMed
    127. Giudice L, Kao LC. Endometriosis. Lancet. 2004 Nov 13-19; 364(9447):1789-99. PMID: 15541453.
      View in: PubMed
    128. McGovern PG, Myers ER, Silva S, Coutifaris C, Carson SA, Legro RS, Schlaff WD, Carr BR, Steinkampf MP, Giudice L, Leppert PC, Diamond MP. Absence of secretory endometrium after false-positive home urine luteinizing hormone testing. Fertil Steril. 2004 Nov; 82(5):1273-7. PMID: 15533341.
      View in: PubMed
    129. Lobo SC, Huang ST, Germeyer A, Dosiou C, Vo KC, Tulac S, Nayak NR, Giudice L. The immune environment in human endometrium during the window of implantation. Am J Reprod Immunol. 2004 Oct; 52(4):244-51. PMID: 15494045.
      View in: PubMed
    130. Tulac S, Dosiou C, Suchanek E, Giudice L. Silencing lamin A/C in human endometrial stromal cells: a model to investigate endometrial gene function and regulation. Mol Hum Reprod. 2004 Oct; 10(10):705-11. PMID: 15347737.
      View in: PubMed
    131. Huang ST, Vo KC, Lyell DJ, Faessen GH, Tulac S, Tibshirani R, Giaccia AJ, Giudice L. Developmental response to hypoxia. FASEB J. 2004 Sep; 18(12):1348-65. PMID: 15333578.
      View in: PubMed
    132. Boldt HB, Kjaer-Sorensen K, Overgaard MT, Weyer K, Poulsen CB, Sottrup-Jensen L, Conover CA, Giudice L, Oxvig C. The Lin12-notch repeats of pregnancy-associated plasma protein-A bind calcium and determine its proteolytic specificity. J Biol Chem. 2004 Sep 10; 279(37):38525-31. PMID: 15262980.
      View in: PubMed
    133. Dosiou C, Lathi RB, Tulac S, Huang ST, Giudice L. Interferon-related and other immune genes are downregulated in peripheral blood leukocytes in the luteal phase of the menstrual cycle. J Clin Endocrinol Metab. 2004 May; 89(5):2501-4. PMID: 15126584.
      View in: PubMed
    134. Weyer K, Overgaard MT, Laursen LS, Nielsen CG, Schmitz A, Christiansen M, Sottrup-Jensen L, Giudice L, Oxvig C. Cell surface adhesion of pregnancy-associated plasma protein-A is mediated by four clusters of basic residues located in its third and fourth CCP module. Eur J Biochem. 2004 Apr; 271(8):1525-35. PMID: 15066178.
      View in: PubMed
    135. Tierney EP, Giudice L. Role of activin A as a mediator of in vitro endometrial stromal cell decidualization via the cyclic adenosine monophosphate pathway. Fertil Steril. 2004 Mar; 81 Suppl 1:899-903. PMID: 15019827.
      View in: PubMed
    136. Overgaard MT, Glerup S, Boldt HB, Rodacker V, Olsen IM, Christiansen M, Sottrup-Jensen L, Giudice L, Oxvig C. Inhibition of proteolysis by the proform of eosinophil major basic protein (proMBP) requires covalent binding to its target proteinase. FEBS Lett. 2004 Feb 27; 560(1-3):147-52. PMID: 14988014.
      View in: PubMed
    137. Giudice L. Microarray expression profiling reveals candidate genes for human uterine receptivity. Am J Pharmacogenomics. 2004; 4(5):299-312. PMID: 15462608.
      View in: PubMed
    138. Tierney EP, Tulac S, Huang ST, Giudice L. Activation of the protein kinase A pathway in human endometrial stromal cells reveals sequential categorical gene regulation. Physiol Genomics. 2003 Dec 16; 16(1):47-66. PMID: 14532334.
      View in: PubMed
    139. Milki AA, Jun SH, Hinckley MD, Westphal LW, Giudice L, Behr B. Comparison of the sex ratio with blastocyst transfer and cleavage stage transfer. J Assist Reprod Genet. 2003 Aug; 20(8):323-6. PMID: 12948095; PMCID: PMC3455273.
    140. Lyell DJ, Lambert-Messerlian GM, Giudice L. Prenatal screening, epidemiology, diagnosis, and management of preeclampsia. Clin Lab Med. 2003 Jun; 23(2):413-42. PMID: 12848452.
      View in: PubMed
    141. Giudice L. Elucidating endometrial function in the post-genomic era. Hum Reprod Update. 2003 May-Jun; 9(3):223-35. PMID: 12859044.
      View in: PubMed
    142. Giudice L. Genomics' role in understanding the pathogenesis of endometriosis. Semin Reprod Med. 2003 May; 21(2):119-24. PMID: 12917781.
      View in: PubMed
    143. Milki AA, Jun SH, Hinckley MD, Behr B, Giudice L, Westphal LM. Incidence of monozygotic twinning with blastocyst transfer compared to cleavage-stage transfer. Fertil Steril. 2003 Mar; 79(3):503-6. PMID: 12620430.
      View in: PubMed
    144. Verhaeghe J, Van Herck E, Billen J, Moerman P, Van Assche FA, Giudice L. Regulation of insulin-like growth factor-I and insulin-like growth factor binding protein-1 concentrations in preterm fetuses. Am J Obstet Gynecol. 2003 Feb; 188(2):485-91. PMID: 12592260.
      View in: PubMed
    145. Morrell MJ, Giudice L, Flynn KL, Seale CG, Paulson AJ, Doñe S, Flaster E, Ferin M, Sauer MV. Predictors of ovulatory failure in women with epilepsy. Ann Neurol. 2002 Dec; 52(6):704-11. PMID: 12447923.
      View in: PubMed
    146. Sun IY, Overgaard MT, Oxvig C, Giudice L. Pregnancy-associated plasma protein A proteolytic activity is associated with the human placental trophoblast cell membrane. J Clin Endocrinol Metab. 2002 Nov; 87(11):5235-40. PMID: 12414897.
      View in: PubMed
    147. Laursen LS, Overgaard MT, Weyer K, Boldt HB, Ebbesen P, Christiansen M, Sottrup-Jensen L, Giudice L, Oxvig C. Cell surface targeting of pregnancy-associated plasma protein A proteolytic activity. Reversible adhesion is mediated by two neighboring short consensus repeats. J Biol Chem. 2002 Dec 06; 277(49):47225-34. PMID: 12370176.
      View in: PubMed
    148. Taylor RN, Lundeen SG, Giudice L. Emerging role of genomics in endometriosis research. Fertil Steril. 2002 Oct; 78(4):694-8. PMID: 12372442.
      View in: PubMed
    149. Laursen LS, Overgaard MT, Nielsen CG, Boldt HB, Hopmann KH, Conover CA, Sottrup-Jensen L, Giudice L, Oxvig C. Substrate specificity of the metalloproteinase pregnancy-associated plasma protein-A (PAPP-A) assessed by mutagenesis and analysis of synthetic peptides: substrate residues distant from the scissile bond are critical for proteolysis. Biochem J. 2002 Oct 01; 367(Pt 1):31-40. PMID: 12241545; PMCID: PMC1222882.
    150. Giudice L. Maternal-fetal conflict--lessons from a transgene. J Clin Invest. 2002 Aug; 110(3):307-9. PMID: 12163449; PMCID: PMC151099.
    151. Søe R, Overgaard MT, Thomsen AR, Laursen LS, Olsen IM, Sottrup-Jensen L, Haaning J, Giudice L, Conover CA, Oxvig C. Expression of recombinant murine pregnancy-associated plasma protein-A (PAPP-A) and a novel variant (PAPP-Ai) with differential proteolytic activity. Eur J Biochem. 2002 Apr; 269(8):2247-56. PMID: 11985604.
      View in: PubMed
    152. Giudice L, Telles TL, Lobo S, Kao L. The molecular basis for implantation failure in endometriosis: on the road to discovery. Ann N Y Acad Sci. 2002 Mar; 955:252-64; discussion 293-5, 396-406. PMID: 11949953.
      View in: PubMed
    153. Imani B, Eijkemans MJ, Faessen GH, Bouchard P, Giudice L, Fauser BC. Prediction of the individual follicle-stimulating hormone threshold for gonadotropin induction of ovulation in normogonadotropic anovulatory infertility: an approach to increase safety and efficiency. Fertil Steril. 2002 Jan; 77(1):83-90. PMID: 11779595.
      View in: PubMed
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