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Benjamin Tang, PhD

Title(s)Assistant Professor, Institute for Neurodegenerative Diseases
SchoolSchool of Medicine
Address675 Nelson Rising Lane
San Francisco CA 94158
Phone415-502-7074
ORCID ORCID Icon0000-0002-3807-0480 Additional info
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    Other Positions
    Title(s)UCSF Weill Institute for Neurosciences


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    Johns Hopkins University, Baltimore, MDPhD06/2009Chemical and Biomolecular Engineering
    University of Delaware, Newark, DEBChE05/2003Chemical Engineering
    University of California, San Francisco, CA2018Diversity, Equity, and Inclusion Champion Training

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Targeted Theranostics for Tuberculosis: A Rifampicin-Loaded Aggregation-Induced Emission Carrier for Granulomas Tracking and Anti-Infection. ACS Nano. 2020 Jun 15. Liao Y, Li B, Zhao Z, Fu Y, Tan Q, Li X, Wang W, Yin J, Shan H, Tang BZ, Huang X. PMID: 32401009.
      View in: PubMed   Mentions:    Fields:    
    2. Multifunctional Supramolecular Assemblies with Aggregation-Induced Emission (AIE) for Cell Line Identification, Cell Contamination Evaluation, and Cancer Cell Discrimination. ACS Nano. 2020 Jun 04. Bai H, Liu Z, Zhang T, Du J, Zhou C, He W, Chau JHC, Kwok RTK, Lam JWY, Tang BZ. PMID: 32484332.
      View in: PubMed   Mentions:    Fields:    
    3. Aggregation-Induced Emission: New Vistas at the Aggregate Level. Angew Chem Int Ed Engl. 2020 Jun 15; 59(25):9888-9907. Zhao Z, Zhang H, Lam JWY, Tang BZ. PMID: 32048428.
      View in: PubMed   Mentions: 1     Fields:    
    4. ACQ-to-AIE Transformation: Tuning Molecular Packing by Regioisomerization for Two-Photon NIR Bioimaging. Angew Chem Int Ed Engl. 2020 May 09. Li Y, Liu S, Ni H, Zhang H, Zhang H, Chuah C, Ma C, Wong KS, Lam JWY, Kwok RTK, Qian J, Lu X, Tang BZ. PMID: 32385974.
      View in: PubMed   Mentions:    Fields:    
    5. Dragonfly-shaped near-infrared AIEgen with optimal fluorescence brightness for precise image-guided cancer surgery. Biomaterials. 2020 Jul; 248:120036. Qi J, Duan X, Liu W, Li Y, Cai Y, Lam JWY, Kwok RTK, Ding D, Tang BZ. PMID: 32302802.
      View in: PubMed   Mentions:    Fields:    
    6. Evoking Photothermy by Capturing Intramolecular Bond Stretching Vibration-Induced Dark-State Energy. ACS Nano. 2020 Apr 28; 14(4):4265-4275. Chen M, Zhang X, Liu J, Liu F, Zhang R, Wei P, Feng H, Tu M, Qin A, Lam JWY, Ding D, Tang BZ. PMID: 32160460.
      View in: PubMed   Mentions:    Fields:    
    7. Multifunctional AuI -based AIEgens: Manipulating Molecular Structures and Boosting Specific Cancer Cell Imaging and Theranostics. Angew Chem Int Ed Engl. 2020 Apr 27; 59(18):7097-7105. Zhang J, Zou H, Lei J, He B, He X, Sung HHY, Kwok RTK, Lam JWY, Zheng L, Tang BZ. PMID: 32049411.
      View in: PubMed   Mentions:    Fields:    
    8. Single AIEgen for multiple tasks: Imaging of dual organelles and evaluation of cell viability. Biomaterials. 2020 Feb 27; 242:119924. Zhang R, Niu G, Liu Z, Chau JHC, Su H, Lee MMS, Gu Y, Kwok RTK, Lam JWY, Tang BZ. PMID: 32145509.
      View in: PubMed   Mentions:    Fields:    
    9. A lipophilic AIEgen for lipid droplet imaging and evaluation of the efficacy of HIF-1 targeting drugs. J Mater Chem B. 2020 Feb 19; 8(7):1516-1523. Shi X, Sung SHP, Lee MMS, Kwok RTK, Sung HHY, Liu H, Lam JWY, Williams ID, Liu B, Tang BZ. PMID: 32003399.
      View in: PubMed   Mentions:    Fields:    
    10. Phage-Guided Targeting, Discriminative Imaging, and Synergistic Killing of Bacteria by AIE Bioconjugates. J Am Chem Soc. 2020 Feb 26; 142(8):3959-3969. He X, Yang Y, Guo Y, Lu S, Du Y, Li JJ, Zhang X, Leung NLC, Zhao Z, Niu G, Yang S, Weng Z, Kwok RTK, Lam JWY, Xie G, Tang BZ. PMID: 31999445.
      View in: PubMed   Mentions:    Fields:    
    11. Less is more: Silver-AIE core@shell nanoparticles for multimodality cancer imaging and synergistic therapy. Biomaterials. 2020 Apr; 238:119834. He X, Peng C, Qiang S, Xiong LH, Zhao Z, Wang Z, Kwok RTK, Lam JWY, Ma N, Tang BZ. PMID: 32058870.
      View in: PubMed   Mentions:    Fields:    
    12. Discovery of 4-Piperazine Isoquinoline Derivatives as Potent and Brain-Permeable Tau Prion Inhibitors with CDK8 Activity. ACS Med Chem Lett. 2020 Feb 13; 11(2):127-132. Grandjean JM, Jiu AY, West JW, Aoyagi A, Droege DG, Elepano M, Hirasawa M, Hirouchi M, Murakami R, Lee J, Sasaki K, Hirano S, Ohyama T, Tang BC, Vaz RJ, Inoue M, Olson SH, Prusiner SB, Conrad J, Paras NA. PMID: 32071678.
      View in: PubMed   Mentions:
    13. Manipulating Solid-State Intramolecular Motion toward Controlled Fluorescence Patterns. ACS Nano. 2020 02 25; 14(2):2090-2098. Liu S, Cheng Y, Li Y, Chen M, Lam JWY, Tang BZ. PMID: 31909986.
      View in: PubMed   Mentions:    Fields:    
    14. Boosting the photodynamic therapy efficiency by using stimuli-responsive and AIE-featured nanoparticles. Biomaterials. 2020 Feb; 232:119749. Li Y, Wu Q, Kang M, Song N, Wang D, Tang BZ. PMID: 31918230.
      View in: PubMed   Mentions:    Fields:    
    15. Dual-Color Emissive AIEgen for Specific and Label-Free Double-Stranded DNA Recognition and Single-Nucleotide Polymorphisms Detection. J Am Chem Soc. 2019 12 26; 141(51):20097-20106. Gao Y, He Z, He X, Zhang H, Weng J, Yang X, Meng F, Luo L, Tang BZ. PMID: 31721575.
      View in: PubMed   Mentions:    Fields:    
    16. Tetraphenylbenzosilole: An AIE Building Block for Deep-Blue Emitters with High Performance in Nondoped Spin-Coating OLEDs. J Org Chem. 2020 Jan 03; 85(1):158-167. Feng W, Su Q, Ma Y, Džolic Z, Huang F, Wang Z, Chen S, Tang BZ. PMID: 31711293.
      View in: PubMed   Mentions: 1     Fields:    
    17. Unusual Through-Space Interactions between Oxygen Atoms that Mediate Inverse Morphochromism of an AIE Luminogen. Angew Chem Int Ed Engl. 2020 May 25; 59(22):8552-8559. Viglianti L, Xie N, Sung HHY, Voityuk AA, Leung NLC, Tu Y, Baldoli C, Williams ID, Kwok RTK, Lam JWY, Licandro E, Blancafort L, Tang BZ. PMID: 31614054.
      View in: PubMed   Mentions:    Fields:    
    18. New Wine in Old Bottles: Prolonging Room-Temperature Phosphorescence of Crown Ethers by Supramolecular Interactions. Angew Chem Int Ed Engl. 2020 Jun 08; 59(24):9293-9298. Wei P, Zhang X, Liu J, Shan GG, Zhang H, Qi J, Zhao W, Sung HH, Williams ID, Lam JWY, Tang BZ. PMID: 31621154.
      View in: PubMed   Mentions:    Fields:    
    19. Ultrafast discrimination of Gram-positive bacteria and highly efficient photodynamic antibacterial therapy using near-infrared photosensitizer with aggregation-induced emission characteristics. Biomaterials. 2020 02; 230:119582. Lee MMS, Xu W, Zheng L, Yu B, Leung ACS, Kwok RTK, Lam JWY, Xu FJ, Wang D, Tang BZ. PMID: 31718884.
      View in: PubMed   Mentions:    Fields:    
    20. Time-Dependent Photodynamic Therapy for Multiple Targets: A Highly Efficient AIE-Active Photosensitizer for Selective Bacterial Elimination and Cancer Cell Ablation. Angew Chem Int Ed Engl. 2020 Jun 08; 59(24):9470-9477. Li Q, Li Y, Min T, Gong J, Du L, Phillips DL, Liu J, Lam JWY, Sung HHY, Williams ID, Kwok RTK, Ho CL, Li K, Wang J, Tang BZ. PMID: 31557385.
      View in: PubMed   Mentions:    Fields:    
    21. Tuning Organelle Specificity and Photodynamic Therapy Efficiency by Molecular Function Design. ACS Nano. 2019 10 22; 13(10):11283-11293. Liu Z, Zou H, Zhao Z, Zhang P, Shan GG, Kwok RTK, Lam JWY, Zheng L, Tang BZ. PMID: 31525947.
      View in: PubMed   Mentions:    Fields:    
    22. Aggregation-Induced Nonlinear Optical Effects of AIEgen Nanocrystals for Ultradeep In Vivo Bioimaging. Adv Mater. 2019 Nov; 31(44):e1904799. Zheng Z, Li D, Liu Z, Peng HQ, Sung HHY, Kwok RTK, Williams ID, Lam JWY, Qian J, Tang BZ. PMID: 31523871.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    23. Solvent and Surface/Interface Effect on the Hierarchical Assemblies of Chiral Aggregation-Induced Emitting Molecules. Langmuir. 2019 Mar 12; 35(10):3805-3813. Li BS, Huang X, Li H, Xia W, Xue S, Xia Q, Tang BZ. PMID: 30767500.
      View in: PubMed   Mentions:    Fields:    
    24. In Situ Generation of Red-Emissive AIEgens from Commercial Sources for Nondoped OLEDs. ACS Omega. 2018 Nov 30; 3(11):16347-16356. Yu Y, Xu Z, Zhao Z, Zhang H, Ma D, Lam JWY, Qin A, Tang BZ. PMID: 31458270.
      View in: PubMed   Mentions:
    25. Nanoparticles that do not adhere to mucus provide uniform and long-lasting drug delivery to airways following inhalation. Sci Adv. 2017 Apr; 3(4):e1601556. Schneider CS, Xu Q, Boylan NJ, Chisholm J, Tang BC, Schuster BS, Henning A, Ensign LM, Lee E, Adstamongkonkul P, Simons BW, Wang SS, Gong X, Yu T, Boyle MP, Suk JS, Hanes J. PMID: 28435870.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    26. Injectable and Glucose-Responsive Hydrogels Based on Boronic Acid-Glucose Complexation. Langmuir. 2016 08 30; 32(34):8743-7. Dong Y, Wang W, Veiseh O, Appel EA, Xue K, Webber MJ, Tang BC, Yang XW, Weir GC, Langer R, Anderson DG. PMID: 27455412.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    27. Frontline Science: Splenic progenitors aid in maintaining high neutrophil numbers at sites of sterile chronic inflammation. J Leukoc Biol. 2016 08; 100(2):253-60. Jhunjhunwala S, Alvarez D, Aresta-DaSilva S, Tang K, Tang BC, Greiner DL, Newburger PE, von Andrian UH, Langer R, Anderson DG. PMID: 26965635.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    28. Poly(glycoamidoamine) Brushes Formulated Nanomaterials for Systemic siRNA and mRNA Delivery in Vivo. Nano Lett. 2016 Feb 10; 16(2):842-8. Dong Y, Dorkin JR, Wang W, Chang PH, Webber MJ, Tang BC, Yang J, Abutbul-Ionita I, Danino D, DeRosa F, Heartlein M, Langer R, Anderson DG. PMID: 26727632.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
    29. Neutrophil Responses to Sterile Implant Materials. PLoS One. 2015; 10(9):e0137550. Jhunjhunwala S, Aresta-DaSilva S, Tang K, Alvarez D, Webber MJ, Tang BC, Lavin DM, Veiseh O, Doloff JC, Bose S, Vegas A, Ma M, Sahay G, Chiu A, Bader A, Langan E, Siebert S, Li J, Greiner DL, Newburger PE, von Andrian UH, Langer R, Anderson DG. PMID: 26355958.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    30. Glucose-responsive insulin activity by covalent modification with aliphatic phenylboronic acid conjugates. Proc Natl Acad Sci U S A. 2015 Feb 24; 112(8):2401-6. Chou DH, Webber MJ, Tang BC, Lin AB, Thapa LS, Deng D, Truong JV, Cortinas AB, Langer R, Anderson DG. PMID: 25675515.
      View in: PubMed   Mentions: 30     Fields:    Translation:Animals
    31. Managing diabetes with nanomedicine: challenges and opportunities. Nat Rev Drug Discov. 2015 Jan; 14(1):45-57. Veiseh O, Tang BC, Whitehead KA, Anderson DG, Langer R. PMID: 25430866.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimals
    32. A perspective on the clinical translation of scaffolds for tissue engineering. Ann Biomed Eng. 2015 Mar; 43(3):641-56. Webber MJ, Khan OF, Sydlik SA, Tang BC, Langer R. PMID: 25201605.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    33. Intraperitoneal delivery of paclitaxel by poly(ether-anhydride) microspheres effectively suppresses tumor growth in a murine metastatic ovarian cancer model. Drug Deliv Transl Res. 2014 Apr 01; 4(2):203-9. Yang M, Yu T, Wood J, Wang YY, Tang BC, Zeng Q, Simons BW, Fu J, Chuang CM, Lai SK, Wu TC, Hung CF, Hanes J. PMID: 24816829.
      View in: PubMed   Mentions: 4     Fields:    
    34. Lipid-like nanomaterials for simultaneous gene expression and silencing in vivo. Adv Healthc Mater. 2014 Sep; 3(9):1392-7. Dong Y, Eltoukhy AA, Alabi CA, Khan OF, Veiseh O, Dorkin JR, Sirirungruang S, Yin H, Tang BC, Pelet JM, Chen D, Gu Z, Xue Y, Langer R, Anderson DG. PMID: 24623658.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    35. Vaginal delivery of paclitaxel via nanoparticles with non-mucoadhesive surfaces suppresses cervical tumor growth. Adv Healthc Mater. 2014 Jul; 3(7):1044-52. Yang M, Yu T, Wang YY, Lai SK, Zeng Q, Miao B, Tang BC, Simons BW, Ensign LM, Liu G, Chan KW, Juang CY, Mert O, Wood J, Fu J, McMahon MT, Wu TC, Hung CF, Hanes J. PMID: 24339398.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    36. Microneedle electrodes toward an amperometric glucose-sensing smart patch. Adv Healthc Mater. 2014 Mar; 3(3):338-42. Invernale MA, Tang BC, York RL, Le L, Hou DY, Anderson DG. PMID: 24039157.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    37. Glucose-responsive microgels integrated with enzyme nanocapsules for closed-loop insulin delivery. ACS Nano. 2013 Aug 27; 7(8):6758-66. Gu Z, Dang TT, Ma M, Tang BC, Cheng H, Jiang S, Dong Y, Zhang Y, Anderson DG. PMID: 23834678.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    38. Mucus-penetrating nanoparticles for vaginal drug delivery protect against herpes simplex virus. Sci Transl Med. 2012 Jun 13; 4(138):138ra79. Ensign LM, Tang BC, Wang YY, Tse TA, Hoen T, Cone R, Hanes J. PMID: 22700955.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansAnimalsCells
    39. Real-time gene delivery vector tracking in the endo-lysosomal pathway of live cells. Microsc Res Tech. 2012 May; 75(5):691-7. Suh J, An Y, Tang BC, Dempsey C, Huang F, Hanes J. PMID: 22095650.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    40. N-acetylcysteine enhances cystic fibrosis sputum penetration and airway gene transfer by highly compacted DNA nanoparticles. Mol Ther. 2011 Nov; 19(11):1981-9. Suk JS, Boylan NJ, Trehan K, Tang BC, Schneider CS, Lin JM, Boyle MP, Zeitlin PL, Lai SK, Cooper MJ, Hanes J. PMID: 21829177.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    41. Development of delivery methods for carbohydrate-based drugs: controlled release of biologically-active short chain fatty acid-hexosamine analogs. Glycoconj J. 2010 May; 27(4):445-59. Aich U, Meledeo MA, Sampathkumar SG, Fu J, Jones MB, Weier CA, Chung SY, Tang BC, Yang M, Hanes J, Yarema KJ. PMID: 20458533.
      View in: PubMed   Mentions: 5     Fields:    
    42. Pentastatin-1, a collagen IV derived 20-mer peptide, suppresses tumor growth in a small cell lung cancer xenograft model. BMC Cancer. 2010 Feb 01; 10:29. Koskimaki JE, Karagiannis ED, Tang BC, Hammers H, Watkins DN, Pili R, Popel AS. PMID: 20122172.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    43. Biodegradable polymer nanoparticles that rapidly penetrate the human mucus barrier. Proc Natl Acad Sci U S A. 2009 Nov 17; 106(46):19268-73. Tang BC, Dawson M, Lai SK, Wang YY, Suk JS, Yang M, Zeitlin P, Boyle MP, Fu J, Hanes J. PMID: 19901335.
      View in: PubMed   Mentions: 86     Fields:    Translation:Humans
    44. Enhanced efficacy of local etoposide delivery by poly(ether-anhydride) particles against small cell lung cancer in vivo. Biomaterials. 2010 Jan; 31(2):339-44. Tang BC, Fu J, Watkins DN, Hanes J. PMID: 19796810.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    45. PEGylation of nanoparticles improves their cytoplasmic transport. Int J Nanomedicine. 2007; 2(4):735-41. Suh J, Choy KL, Lai SK, Suk JS, Tang BC, Prabhu S, Hanes J. PMID: 18203439.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    46. Protein disulfide isomerase, but not binding protein, overexpression enhances secretion of a non-disulfide-bonded protein in yeast. Biotechnol Bioeng. 2004 Feb 05; 85(3):340-50. Smith JD, Tang BC, Robinson AS. PMID: 14748090.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
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