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Benjamin Tang, PhD

TitleAssistant Professor
InstitutionUniversity of California San Francisco
DepartmentInstitute for Neurodegenerative Diseases
Address675 Nelson Rising Lane
San Francisco CA 94158
Phone415-502-7074
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    Collapse Biography 
    Collapse Education and Training
    Johns Hopkins University, Baltimore, MDPhD06/2009Chemical and Biomolecular Engineering
    University of Delaware, Newark, DEBChE05/2003Chemical Engineering

    Collapse ORNG Applications 
    Collapse In The News

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Qi J, Sun C, Li D, Zhang H, Yu W, Zebibula A, Lam JWY, Xi W, Zhu L, Cai F, Wei P, Zhu C, Kwok RTK, Streich LL, Prevedel R, Qian J, Tang B. Aggregation-Induced Emission Luminogen with Near-Infrared-II Excitation and Near-Infrared-I Emission for Ultradeep Intravital Two-Photon Microscopy. ACS Nano. 2018 Aug 01. PMID: 30059201.
      View in: PubMed
    2. Qi J, Chen C, Ding D, Tang B. Aggregation-Induced Emission Luminogens: Union Is Strength, Gathering Illuminates Healthcare. Adv Healthc Mater. 2018 Jul 03; e1800477. PMID: 29969201.
      View in: PubMed
    3. Feng X, Qi C, Feng HT, Zhao Z, Sung HHY, Williams ID, Kwok RTK, Lam JWY, Qin A, Tang B. Dual fluorescence of tetraphenylethylene-substituted pyrenes with aggregation-induced emission characteristics for white-light emission. Chem Sci. 2018 Jul 07; 9(25):5679-5687. PMID: 30062002.
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    4. Chen J, Gao M, Wang L, Li S, He J, Qin A, Ren L, Wang Y, Tang B. Aggregation-Induced Emission Probe for Study of the Bactericidal Mechanism of Antimicrobial Peptides. ACS Appl Mater Interfaces. 2018 Apr 11; 10(14):11436-11442. PMID: 29564898.
      View in: PubMed
    5. Li X, Jiang M, Lam JWY, Tang B, Qu JY. Mitochondrial Imaging with Combined Fluorescence and Stimulated Raman Scattering Microscopy Using a Probe of the Aggregation-Induced Emission Characteristic. J Am Chem Soc. 2017 Nov 29; 139(47):17022-17030. PMID: 29111701.
      View in: PubMed
    6. Feng G, Li JLY, Claser C, Balachander A, Tan Y, Goh CC, Kwok IWH, RĂ©nia L, Tang B, Ng LG, Liu B. Dual modal ultra-bright nanodots with aggregation-induced emission and gadolinium-chelation for vascular integrity and leakage detection. Biomaterials. 2018 Jan; 152:77-85. PMID: 29111495.
      View in: PubMed
    7. Gu X, Kwok RTK, Lam JWY, Tang B. AIEgens for biological process monitoring and disease theranostics. Biomaterials. 2017 Nov; 146:115-135. PMID: 28915410.
      View in: PubMed
    8. Qi J, Fang Y, Kwok RTK, Zhang X, Hu X, Lam JWY, Ding D, Tang B. Highly Stable Organic Small Molecular Nanoparticles as an Advanced and Biocompatible Phototheranostic Agent of Tumor in Living Mice. ACS Nano. 2017 Jul 25; 11(7):7177-7188. PMID: 28692799.
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    9. Wu Y, He B, Quan C, Zheng C, Deng H, Hu R, Zhao Z, Huang F, Qin A, Tang B. Metal-Free Poly-Cycloaddition of Activated Azide and Alkynes toward Multifunctional Polytriazoles: Aggregation-Induced Emission, Explosive Detection, Fluorescent Patterning, and Light Refraction. Macromol Rapid Commun. 2017 Sep; 38(18). PMID: 28493513.
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    10. Schneider CS, Xu Q, Boylan NJ, Chisholm J, Tang B, Schuster BS, Henning A, Ensign LM, Lee E, Adstamongkonkul P, Simons BW, Wang SS, Gong X, Yu T, Boyle MP, Suk JS, Hanes J. Nanoparticles that do not adhere to mucus provide uniform and long-lasting drug delivery to airways following inhalation. Sci Adv. 2017 Apr; 3(4):e1601556. PMID: 28435870.
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    11. Wu Y, He B, Wang J, Hu R, Zhao Z, Huang F, Qin A, Tang B. Efficient and Regioselectivity-Tunable Metal-Free Polycycloaddition of Activated Azide and Alkynes. Macromol Rapid Commun. 2017 Feb; 38(4). PMID: 28045218.
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    12. Jiang S, Huang TY, Wang KM, Tang B, Yu Q. A New Determination Method of the Solubility Parameter of Polymer Based on AIE. Molecules. 2016 Dec 30; 22(1). PMID: 28042835.
      View in: PubMed
    13. Tyagi A, Chu KL, Abidi IH, Cagang AA, Zhang Q, Leung NLC, Zhao E, Tang B, Luo Z. Single-probe multistate detection of DNA via aggregation-induced emission on a graphene oxide platform. Acta Biomater. 2017 03 01; 50:334-343. PMID: 27940196.
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    14. Dong Y, Wang W, Veiseh O, Appel EA, Xue K, Webber MJ, Tang B, Yang XW, Weir GC, Langer R, Anderson DG. Injectable and Glucose-Responsive Hydrogels Based on Boronic Acid-Glucose Complexation. Langmuir. 2016 Aug 30; 32(34):8743-7. PMID: 27455412.
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    15. Gao M, Chen J, Lin G, Li S, Wang L, Qin A, Zhao Z, Ren L, Wang Y, Tang B. Long-Term Tracking of the Osteogenic Differentiation of Mouse BMSCs by Aggregation-Induced Emission Nanoparticles. ACS Appl Mater Interfaces. 2016 Jul 20; 8(28):17878-84. PMID: 27400339.
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    16. Jhunjhunwala S, Alvarez D, Aresta-DaSilva S, Tang K, Tang B, Greiner DL, Newburger PE, von Andrian UH, Langer R, Anderson DG. Frontline Science: Splenic progenitors aid in maintaining high neutrophil numbers at sites of sterile chronic inflammation. J Leukoc Biol. 2016 08; 100(2):253-60. PMID: 26965635; PMCID: PMC4945357 [Available on 08/01/17].
    17. Gao M, Wang L, Chen J, Li S, Lu G, Wang L, Wang Y, Ren L, Qin A, Tang B. Aggregation-Induced Emission Active Probe for Light-Up Detection of Anionic Surfactants and Wash-Free Bacterial Imaging. Chemistry. 2016 Apr 04; 22(15):5107-12. PMID: 26890013.
      View in: PubMed
    18. Dong Y, Dorkin JR, Wang W, Chang PH, Webber MJ, Tang B, Yang J, Abutbul-Ionita I, Danino D, DeRosa F, Heartlein M, Langer R, Anderson DG. Poly(glycoamidoamine) Brushes Formulated Nanomaterials for Systemic siRNA and mRNA Delivery in Vivo. Nano Lett. 2016 Feb 10; 16(2):842-8. PMID: 26727632.
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    19. Leung CW, Wang Z, Zhao E, Hong Y, Chen S, Kwok RT, Leung AC, Wen R, Li B, Lam JW, Tang B. A Lysosome-Targeting AIEgen for Autophagy Visualization. Adv Healthc Mater. 2016 Feb 18; 5(4):427-31. PMID: 26688031.
      View in: PubMed
    20. Feng G, Qin W, Hu Q, Tang B, Liu B. Cellular and Mitochondrial Dual-Targeted Organic Dots with Aggregation-Induced Emission Characteristics for Image-Guided Photodynamic Therapy. Adv Healthc Mater. 2015 Dec 09; 4(17):2667-76. PMID: 26479020.
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    21. Jhunjhunwala S, Aresta-DaSilva S, Tang K, Alvarez D, Webber MJ, Tang B, Lavin DM, Veiseh O, Doloff JC, Bose S, Vegas A, Ma M, Sahay G, Chiu A, Bader A, Langan E, Siebert S, Li J, Greiner DL, Newburger PE, von Andrian UH, Langer R, Anderson DG. Neutrophil Responses to Sterile Implant Materials. PLoS One. 2015; 10(9):e0137550. PMID: 26355958; PMCID: PMC4565661.
    22. Geng J, Goh CC, Qin W, Liu R, Tomczak N, Ng LG, Tang B, Liu B. Silica shelled and block copolymer encapsulated red-emissive AIE nanoparticles with 50% quantum yield for two-photon excited vascular imaging. Chem Commun (Camb). 2015 Sep 07; 51(69):13416-9. PMID: 26213866.
      View in: PubMed
    23. Yuan Y, Kwok RT, Tang B, Liu B. Smart Probe for Tracing Cancer Therapy: Selective Cancer Cell Detection, Image-Guided Ablation, and Prediction of Therapeutic Response In Situ. Small. 2015 Sep; 11(36):4682-90. PMID: 26113312.
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    24. Chen L, Wang YH, He B, Nie H, Hu R, Huang F, Qin A, Zhou XS, Zhao Z, Tang B. Multichannel conductance of folded single-molecule wires aided by through-space conjugation. Angew Chem Int Ed Engl. 2015 Mar 27; 54(14):4231-5. PMID: 25694026.
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    25. Chou DH, Webber MJ, Tang B, Lin AB, Thapa LS, Deng D, Truong JV, Cortinas AB, Langer R, Anderson DG. Glucose-responsive insulin activity by covalent modification with aliphatic phenylboronic acid conjugates. Proc Natl Acad Sci U S A. 2015 Feb 24; 112(8):2401-6. PMID: 25675515; PMCID: PMC4345600.
    26. Gao M, Hu Q, Feng G, Tomczak N, Liu R, Xing B, Tang B, Liu B. A multifunctional probe with aggregation-induced emission characteristics for selective fluorescence imaging and photodynamic killing of bacteria over mammalian cells. Adv Healthc Mater. 2015 Apr 02; 4(5):659-63. PMID: 25530179.
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    27. Veiseh O, Tang B, Whitehead KA, Anderson DG, Langer R. Managing diabetes with nanomedicine: challenges and opportunities. Nat Rev Drug Discov. 2015 Jan; 14(1):45-57. PMID: 25430866; PMCID: PMC4751590.
    28. Ding D, Mao D, Li K, Wang X, Qin W, Liu R, Chiam DS, Tomczak N, Yang Z, Tang B, Kong D, Liu B. Precise and long-term tracking of adipose-derived stem cells and their regenerative capacity via superb bright and stable organic nanodots. ACS Nano. 2014 Dec 23; 8(12):12620-31. PMID: 25427294.
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    29. Yuan Y, Kwok RT, Zhang R, Tang B, Liu B. Targeted theranostic prodrugs based on an aggregation-induced emission (AIE) luminogen for real-time dual-drug tracking. Chem Commun (Camb). 2014 Oct 09; 50(78):11465-8. PMID: 25137179.
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    30. Chen L, Jiang Y, Nie H, Hu R, Kwok HS, Huang F, Qin A, Zhao Z, Tang B. Rational design of aggregation-induced emission luminogen with weak electron donor-acceptor interaction to achieve highly efficient undoped bilayer OLEDs. ACS Appl Mater Interfaces. 2014 Oct 08; 6(19):17215-25. PMID: 25254940.
      View in: PubMed
    31. Webber MJ, Khan OF, Sydlik SA, Tang B, Langer R. A perspective on the clinical translation of scaffolds for tissue engineering. Ann Biomed Eng. 2015 Mar; 43(3):641-56. PMID: 25201605; PMCID: PMC4785597.
    32. Feng G, Tay CY, Chui QX, Liu R, Tomczak N, Liu J, Tang B, Leong DT, Liu B. Ultrabright organic dots with aggregation-induced emission characteristics for cell tracking. Biomaterials. 2014 Oct; 35(30):8669-77. PMID: 25002264.
      View in: PubMed
    33. Liang G, Ni H, Bao S, Zhu F, Gao H, Wu Q, Tang B. Amphiphilic nanocapsules entangled with organometallic coordination polymers for controlled cargo release. Langmuir. 2014 Jun 03; 30(21):6294-301. PMID: 24828951.
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    34. Yang M, Yu T, Wood J, Wang YY, Tang B, Zeng Q, Simons BW, Fu J, Chuang CM, Lai SK, Wu TC, Hung CF, Hanes J. Intraperitoneal delivery of paclitaxel by poly(ether-anhydride) microspheres effectively suppresses tumor growth in a murine metastatic ovarian cancer model. Drug Deliv Transl Res. 2014 Apr 01; 4(2):203-9. PMID: 24816829; PMCID: PMC3956079.
    35. Wang D, Qian J, Qin W, Qin A, Tang B, He S. Biocompatible and photostable AIE dots with red emission for in vivo two-photon bioimaging. Sci Rep. 2014 Mar 17; 4:4279. PMID: 24632722; PMCID: PMC3955920.
    36. Dong Y, Eltoukhy AA, Alabi CA, Khan OF, Veiseh O, Dorkin JR, Sirirungruang S, Yin H, Tang B, Pelet JM, Chen D, Gu Z, Xue Y, Langer R, Anderson DG. Lipid-like nanomaterials for simultaneous gene expression and silencing in vivo. Adv Healthc Mater. 2014 Sep; 3(9):1392-7. PMID: 24623658; PMCID: PMC4160381.
    37. Lou X, Hong Y, Chen S, Leung CW, Zhao N, Situ B, Lam JW, Tang B. A selective glutathione probe based on AIE fluorogen and its application in enzymatic activity assay. Sci Rep. 2014 Mar 07; 4:4272. PMID: 24603274; PMCID: PMC3945925.
    38. Yang M, Yu T, Wang YY, Lai SK, Zeng Q, Miao B, Tang B, Simons BW, Ensign LM, Liu G, Chan KW, Juang CY, Mert O, Wood J, Fu J, McMahon MT, Wu TC, Hung CF, Hanes J. Vaginal delivery of paclitaxel via nanoparticles with non-mucoadhesive surfaces suppresses cervical tumor growth. Adv Healthc Mater. 2014 Jul; 3(7):1044-52. PMID: 24339398; PMCID: PMC4059793.
    39. Invernale MA, Tang B, York RL, Le L, Hou DY, Anderson DG. Microneedle electrodes toward an amperometric glucose-sensing smart patch. Adv Healthc Mater. 2014 Mar; 3(3):338-42. PMID: 24039157.
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    40. Li K, Ding D, Prashant C, Qin W, Yang CT, Tang B, Liu B. Gadolinium-functionalized aggregation-induced emission dots as dual-modality probes for cancer metastasis study. Adv Healthc Mater. 2013 Dec; 2(12):1600-5. PMID: 23836611.
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    41. Gu Z, Dang TT, Ma M, Tang B, Cheng H, Jiang S, Dong Y, Zhang Y, Anderson DG. Glucose-responsive microgels integrated with enzyme nanocapsules for closed-loop insulin delivery. ACS Nano. 2013 Aug 27; 7(8):6758-66. PMID: 23834678.
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    42. Zhao E, Hong Y, Chen S, Leung CW, Chan CY, Kwok RT, Lam JW, Tang B. Highly fluorescent and photostable probe for long-term bacterial viability assay based on aggregation-induced emission. Adv Healthc Mater. 2014 Jan; 3(1):88-96. PMID: 23814037.
      View in: PubMed
    43. Ding D, Li K, Qin W, Zhan R, Hu Y, Liu J, Tang B, Liu B. Conjugated polymer amplified far-red/near-infrared fluorescence from nanoparticles with aggregation-induced emission characteristics for targeted in vivo imaging. Adv Healthc Mater. 2013 Mar; 2(3):500-7. PMID: 23184536.
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    44. Geng J, Li K, Ding D, Zhang X, Qin W, Liu J, Tang B, Liu B. Lipid-PEG-folate encapsulated nanoparticles with aggregation induced emission characteristics: cellular uptake mechanism and two-photon fluorescence imaging. Small. 2012 Dec 07; 8(23):3655-63. PMID: 22893564.
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    45. Ding D, Wang G, Liu J, Li K, Pu KY, Hu Y, Ng JC, Tang B, Liu B. Hyperbranched conjugated polyelectrolyte for dual-modality fluorescence and magnetic resonance cancer imaging. Small. 2012 Nov 19; 8(22):3523-30. PMID: 22893375.
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    46. Ensign LM, Tang B, Wang YY, Tse TA, Hoen T, Cone R, Hanes J. Mucus-penetrating nanoparticles for vaginal drug delivery protect against herpes simplex virus. Sci Transl Med. 2012 Jun 13; 4(138):138ra79. PMID: 22700955; PMCID: PMC3817739.
    47. Suh J, An Y, Tang B, Dempsey C, Huang F, Hanes J. Real-time gene delivery vector tracking in the endo-lysosomal pathway of live cells. Microsc Res Tech. 2012 May; 75(5):691-7. PMID: 22095650; PMCID: PMC3305830.
    48. Suk JS, Boylan NJ, Trehan K, Tang B, Schneider CS, Lin JM, Boyle MP, Zeitlin PL, Lai SK, Cooper MJ, Hanes J. N-acetylcysteine enhances cystic fibrosis sputum penetration and airway gene transfer by highly compacted DNA nanoparticles. Mol Ther. 2011 Nov; 19(11):1981-9. PMID: 21829177; PMCID: PMC3222526.
    49. Aich U, Meledeo MA, Sampathkumar SG, Fu J, Jones MB, Weier CA, Chung SY, Tang B, Yang M, Hanes J, Yarema KJ. Development of delivery methods for carbohydrate-based drugs: controlled release of biologically-active short chain fatty acid-hexosamine analogs. Glycoconj J. 2010 May; 27(4):445-59. PMID: 20458533; PMCID: PMC3038847.
    50. Koskimaki JE, Karagiannis ED, Tang B, Hammers H, Watkins DN, Pili R, Popel AS. Pentastatin-1, a collagen IV derived 20-mer peptide, suppresses tumor growth in a small cell lung cancer xenograft model. BMC Cancer. 2010 Feb 01; 10:29. PMID: 20122172; PMCID: PMC2824711.
    51. Tang B, Dawson M, Lai SK, Wang YY, Suk JS, Yang M, Zeitlin P, Boyle MP, Fu J, Hanes J. Biodegradable polymer nanoparticles that rapidly penetrate the human mucus barrier. Proc Natl Acad Sci U S A. 2009 Nov 17; 106(46):19268-73. PMID: 19901335; PMCID: PMC2780804.
    52. Tang B, Fu J, Watkins DN, Hanes J. Enhanced efficacy of local etoposide delivery by poly(ether-anhydride) particles against small cell lung cancer in vivo. Biomaterials. 2010 Jan; 31(2):339-44. PMID: 19796810; PMCID: PMC2784125.
    53. Zeng Q, Jim CK, Lam JW, Dong Y, Li Z, Qin J, Tang B. A New Disubstituted Polyacetylene for the Detection of a-Amino Acids. Macromol Rapid Commun. 2009 Feb 02; 30(3):170-5. PMID: 21706594.
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    54. Zeng Q, Cai P, Li Z, Qin J, Tang B. An imidazole-functionalized polyacetylene: convenient synthesis and selective chemosensor for metal ions and cyanide. Chem Commun (Camb). 2008 Mar 07; (9):1094-6. PMID: 18292901.
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    55. Suh J, Choy KL, Lai SK, Suk JS, Tang B, Prabhu S, Hanes J. PEGylation of nanoparticles improves their cytoplasmic transport. Int J Nanomedicine. 2007; 2(4):735-41. PMID: 18203439; PMCID: PMC2676827.
    56. Zeng Q, Li Z, Dong Y, Di C, Qin A, Hong Y, Ji L, Zhu Z, Jim CK, Yu G, Li Q, Li Z, Liu Y, Qin J, Tang B. Fluorescence enhancements of benzene-cored luminophors by restricted intramolecular rotations: AIE and AIEE effects. Chem Commun (Camb). 2007 Jan 07; (1):70-2. PMID: 17279264.
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    57. Smith JD, Tang B, Robinson AS. Protein disulfide isomerase, but not binding protein, overexpression enhances secretion of a non-disulfide-bonded protein in yeast. Biotechnol Bioeng. 2004 Feb 05; 85(3):340-50. PMID: 14748090.
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