Benjamin Tang, PhD

Title(s)Assistant Professor, Institute for Neurodegenerative Diseases
SchoolSchool of Medicine
Address675 Nelson Rising Lane
San Francisco CA 94158
ORCID ORCID Icon0000-0002-3807-0480 Additional info
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    Other Positions
    Title(s)UCSF Weill Institute for Neurosciences

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    Johns Hopkins University, Baltimore, MDPhD06/2009Chemical and Biomolecular Engineering
    University of Delaware, Newark, DEBChE05/2003Chemical Engineering
    University of California, San Francisco, CA2018Diversity, Equity, and Inclusion Champion Training

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. AIEgen-loaded nanofibrous membrane as photodynamic/photothermal antimicrobial surface for sunlight-triggered bioprotection. Biomaterials. 2021 Jul 03; 276:121007. Li M, Wen H, Li H, Yan ZC, Li Y, Wang L, Wang D, Tang BZ. PMID: 34237505.
      View in: PubMed   Mentions:    Fields:    
    2. Visualization and Manipulation of Solid-State Molecular Motions in Cocrystallization Processes. J Am Chem Soc. 2021 Jun 30; 143(25):9468-9477. Wang H, Li Q, Zhang J, Zhang H, Shu Y, Zhao Z, Jiang W, Du L, Phillips DL, Lam JWY, Sung HHY, Williams ID, Lu R, Tang BZ. PMID: 34152134.
      View in: PubMed   Mentions:    Fields:    
    3. Molecular Engineering of High-Performance Aggregation-Induced Emission Photosensitizers to Boost Cancer Theranostics Mediated by Acid-Triggered Nucleus-Targeted Nanovectors. ACS Nano. 2021 06 22; 15(6):10689-10699. Zhang Z, Xu W, Xiao P, Kang M, Yan D, Wen H, Song N, Wang D, Tang BZ. PMID: 34077187.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Cationic Tricyclic AIEgens for Concomitant Bacterial Discrimination and Inhibition. Adv Healthc Mater. 2021 May 21; e2100136. Wang B, Wu H, Hu R, Liu X, Liu Z, Wang Z, Qin A, Tang BZ. PMID: 34019741.
      View in: PubMed   Mentions:    Fields:    
    5. Heteroaromatic Hyperbranched Polyelectrolytes: Multicomponent Polyannulation and Photodynamic Biopatterning. Angew Chem Int Ed Engl. 2021 May 14. Liu X, Xiao M, Xue K, Li M, Liu D, Wang Y, Yang X, Hu Y, Kwok RTK, Qin A, Zhu C, Lam JWY, Tang BZ. PMID: 33991002.
      View in: PubMed   Mentions:    Fields:    
    6. One-for-all phototheranostics: Single component AIE dots as multi-modality theranostic agent for fluorescence-photoacoustic imaging-guided synergistic cancer therapy. Biomaterials. 2021 07; 274:120892. Wen H, Zhang Z, Kang M, Li H, Xu W, Guo H, Li Y, Tan Y, Wen Z, Wu Q, Huang J, Xi L, Li K, Wang L, Wang D, Tang BZ. PMID: 34020267.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    7. Functionalization of Silk by AIEgens through Facile Bioconjugation: Full-Color Fluorescence and Long-Term Bioimaging. Angew Chem Int Ed Engl. 2021 05 25; 60(22):12424-12430. Liu C, Bai H, He B, He X, Zhang J, Chen C, Qiu Y, Hu R, Zhao F, Zhang Y, He W, Chau JHC, Chen S, Lam JWY, Tang BZ. PMID: 33760356.
      View in: PubMed   Mentions:    Fields:    
    8. Association Between Premorbid Beta-Blocker Exposure and Sepsis Outcomes-The Beta-Blockers in European and Australian/American Septic Patients (BEAST) Study. Crit Care Med. 2021 Apr 28. Tan K, Harazim M, Simpson A, Tan YC, Gunawan G, Robledo KP, Whitehead C, Tang B, Mclean A, Nalos M. PMID: 33938711.
      View in: PubMed   Mentions:    Fields:    
    9. Patient-derived microvesicles/AIE luminogen hybrid system for personalized sonodynamic cancer therapy in patient-derived xenograft models. Biomaterials. 2021 05; 272:120755. Duo Y, Zhu D, Sun X, Suo M, Zheng Z, Jiang W, Tang BZ. PMID: 33819814.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. BioAIEgens derived from rosin: how does molecular motion affect their photophysical processes in solid state? Nat Commun. 2021 03 19; 12(1):1773. Cai XM, Lin Y, Li Y, Chen X, Wang Z, Zhao X, Huang S, Zhao Z, Tang BZ. PMID: 33741995.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    11. Facilitation of molecular motion to develop turn-on photoacoustic bioprobe for detecting nitric oxide in encephalitis. Nat Commun. 2021 02 11; 12(1):960. Qi J, Feng L, Zhang X, Zhang H, Huang L, Zhou Y, Zhao Z, Duan X, Xu F, Kwok RTK, Lam JWY, Ding D, Xue X, Tang BZ. PMID: 33574252.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    12. Robust Supramolecular Nano-Tunnels Built from Molecular Bricks*. Angew Chem Int Ed Engl. 2021 Mar 22; 60(13):7148-7154. Wei P, He X, Zheng Z, He D, Li Q, Gong J, Zhang J, Sung HHY, Williams ID, Lam JWY, Liu M, Tang BZ. PMID: 33300645.
      View in: PubMed   Mentions:    Fields:    
    13. NIR-II AIEgens: A Win-Win Integration towards Bioapplications. Angew Chem Int Ed Engl. 2021 03 29; 60(14):7476-7487. Xu W, Wang D, Tang BZ. PMID: 32515530.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    14. AIEgens for microbial detection and antimicrobial therapy. Biomaterials. 2021 01; 268:120598. Bai H, He W, Chau JHC, Zheng Z, Kwok RTK, Lam JWY, Tang BZ. PMID: 33321291.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. Enantiomeric Switching of the Circularly Polarized Luminescence Processes in a Hierarchical Biomimetic System by Film Tilting. ACS Nano. 2021 01 26; 15(1):1397-1406. Khorloo M, Yu X, Cheng Y, Zhang H, Yu S, Lam JWY, Zhu M, Tang BZ. PMID: 33275400.
      View in: PubMed   Mentions:    Fields:    
    16. Unusual light-driven amplification through unexpected regioselective photogeneration of five-membered azaheterocyclic AIEgen. Chem Sci. 2020 Oct 19; 12(2):709-717. Li Q, Gong J, Li Y, Zhang R, Wang H, Zhang J, Yan H, Lam JWY, Sung HHY, Williams ID, Kwok RTK, Li MH, Wang J, Tang BZ. PMID: 34163804.
      View in: PubMed   Mentions:
    17. Exosome-Mimetic Supramolecular Vesicles with Reversible and Controllable Fusion and Fission*. Angew Chem Int Ed Engl. 2020 11 23; 59(48):21510-21514. Li J, Peng K, Li Y, Wang J, Huang J, Yan Y, Wang D, Tang BZ. PMID: 32779357.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    18. Simultaneously boosting the conjugation, brightness and solubility of organic fluorophores by using AIEgens. Chem Sci. 2020 Jul 27; 11(32):8438-8447. Qi J, Duan X, Cai Y, Jia S, Chen C, Zhao Z, Li Y, Peng HQ, Kwok RTK, Lam JWY, Ding D, Tang BZ. PMID: 34123103.
      View in: PubMed   Mentions:
    19. Structural and process controls of AIEgens for NIR-II theranostics. Chem Sci. 2020 Jun 12; 12(10):3427-3436. Liu S, Li Y, Kwok RTK, Lam JWY, Tang BZ. PMID: 34163616.
      View in: PubMed   Mentions:
    20. Cancer cell discrimination and dynamic viability monitoring through wash-free bioimaging using AIEgens. Chem Sci. 2020 Apr 30; 11(29):7676-7684. Zhang R, Niu G, Lu Q, Huang X, Chau JHC, Kwok RTK, Yu X, Li MH, Lam JWY, Tang BZ. PMID: 34094146.
      View in: PubMed   Mentions:
    21. Two Are Better Than One: A Design Principle for Ultralong-Persistent Luminescence of Pure Organics. . 2020 Jun; 32(22):e2001026. Alam P, Leung NLC, Liu J, Cheung TS, Zhang X, He Z, Kwok RTK, Lam JWY, Sung HHY, Williams ID, Chan CCS, Wong KS, Peng Q, Tang BZ. PMID: 32323364.
      View in: PubMed   Mentions:
    22. One stone, three birds: one AIEgen with three colors for fast differentiation of three pathogens. Chem Sci. 2020 Apr 14; 11(18):4730-4740. Zhou C, Jiang M, Du J, Bai H, Shan G, Kwok RTK, Chau JHC, Zhang J, Lam JWY, Huang P, Tang BZ. PMID: 34122928.
      View in: PubMed   Mentions:
    23. Three-Pronged Attack by Homologous Far-red/NIR AIEgens to Achieve 1+1+1>3 Synergistic Enhanced Photodynamic Therapy. Angew Chem Int Ed Engl. 2020 06 08; 59(24):9610-9616. Xu W, Lee MMS, Nie JJ, Zhang Z, Kwok RTK, Lam JWY, Xu FJ, Wang D, Tang BZ. PMID: 32119182.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    24. Design of AIEgens for near-infrared IIb imaging through structural modulation at molecular and morphological levels. Nat Commun. 2020 03 09; 11(1):1255. Li Y, Cai Z, Liu S, Zhang H, Wong STH, Lam JWY, Kwok RTK, Qian J, Tang BZ. PMID: 32152288.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    25. Bioinspired Simultaneous Changes in Fluorescence Color, Brightness, and Shape of Hydrogels Enabled by AIEgens. Adv Mater. 2020 Mar; 32(11):e1906493. Li Z, Liu P, Ji X, Gong J, Hu Y, Wu W, Wang X, Peng HQ, Kwok RTK, Lam JWY, Lu J, Tang BZ. PMID: 32022969.
      View in: PubMed   Mentions: 1     Fields:    
    26. Discovery of 4-Piperazine Isoquinoline Derivatives as Potent and Brain-Permeable Tau Prion Inhibitors with CDK8 Activity. ACS Med Chem Lett. 2020 Feb 13; 11(2):127-132. Grandjean JM, Jiu AY, West JW, Aoyagi A, Droege DG, Elepano M, Hirasawa M, Hirouchi M, Murakami R, Lee J, Sasaki K, Hirano S, Ohyama T, Tang BC, Vaz RJ, Inoue M, Olson SH, Prusiner SB, Conrad J, Paras NA. PMID: 32071678.
      View in: PubMed   Mentions:
    27. Highly efficient singlet oxygen generation, two-photon photodynamic therapy and melanoma ablation by rationally designed mitochondria-specific near-infrared AIEgens. Chem Sci. 2020 Jan 21; 11(9):2494-2503. Zheng Z, Liu H, Zhai S, Zhang H, Shan G, Kwok RTK, Ma C, Sung HHY, Williams ID, Lam JWY, Wong KS, Hu X, Tang BZ. PMID: 34084415.
      View in: PubMed   Mentions:
    28. Efficient Near-Infrared Photosensitizer with Aggregation-Induced Emission for Imaging-Guided Photodynamic Therapy in Multiple Xenograft Tumor Models. ACS Nano. 2020 01 28; 14(1):854-866. Dai J, Li Y, Long Z, Jiang R, Zhuang Z, Wang Z, Zhao Z, Lou X, Xia F, Tang BZ. PMID: 31820925.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    29. Polymorph selectivity of an AIE luminogen under nano-confinement to visualize polymer microstructures. Chem Sci. 2019 Nov 22; 11(4):997-1005. Khorloo M, Cheng Y, Zhang H, Chen M, Sung HHY, Williams ID, Lam JWY, Tang BZ. PMID: 34084354.
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    30. Nanoparticles that do not adhere to mucus provide uniform and long-lasting drug delivery to airways following inhalation. Sci Adv. 2017 Apr; 3(4):e1601556. Schneider CS, Xu Q, Boylan NJ, Chisholm J, Tang BC, Schuster BS, Henning A, Ensign LM, Lee E, Adstamongkonkul P, Simons BW, Wang SS, Gong X, Yu T, Boyle MP, Suk JS, Hanes J. PMID: 28435870.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimals
    31. Injectable and Glucose-Responsive Hydrogels Based on Boronic Acid-Glucose Complexation. Langmuir. 2016 08 30; 32(34):8743-7. Dong Y, Wang W, Veiseh O, Appel EA, Xue K, Webber MJ, Tang BC, Yang XW, Weir GC, Langer R, Anderson DG. PMID: 27455412.
      View in: PubMed   Mentions: 18     Fields:    Translation:Cells
    32. Frontline Science: Splenic progenitors aid in maintaining high neutrophil numbers at sites of sterile chronic inflammation. J Leukoc Biol. 2016 08; 100(2):253-60. Jhunjhunwala S, Alvarez D, Aresta-DaSilva S, Tang K, Tang BC, Greiner DL, Newburger PE, von Andrian UH, Langer R, Anderson DG. PMID: 26965635.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    33. Poly(glycoamidoamine) Brushes Formulated Nanomaterials for Systemic siRNA and mRNA Delivery in Vivo. . 2016 Feb 10; 16(2):842-8. Dong Y, Dorkin JR, Wang W, Chang PH, Webber MJ, Tang BC, Yang J, Abutbul-Ionita I, Danino D, DeRosa F, Heartlein M, Langer R, Anderson DG. PMID: 26727632.
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    34. Neutrophil Responses to Sterile Implant Materials. PLoS One. 2015; 10(9):e0137550. Jhunjhunwala S, Aresta-DaSilva S, Tang K, Alvarez D, Webber MJ, Tang BC, Lavin DM, Veiseh O, Doloff JC, Bose S, Vegas A, Ma M, Sahay G, Chiu A, Bader A, Langan E, Siebert S, Li J, Greiner DL, Newburger PE, von Andrian UH, Langer R, Anderson DG. PMID: 26355958.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    35. Glucose-responsive insulin activity by covalent modification with aliphatic phenylboronic acid conjugates. Proc Natl Acad Sci U S A. 2015 Feb 24; 112(8):2401-6. Chou DH, Webber MJ, Tang BC, Lin AB, Thapa LS, Deng D, Truong JV, Cortinas AB, Langer R, Anderson DG. PMID: 25675515.
      View in: PubMed   Mentions: 43     Fields:    Translation:Animals
    36. Managing diabetes with nanomedicine: challenges and opportunities. Nat Rev Drug Discov. 2015 Jan; 14(1):45-57. Veiseh O, Tang BC, Whitehead KA, Anderson DG, Langer R. PMID: 25430866.
      View in: PubMed   Mentions: 85     Fields:    Translation:HumansAnimals
    37. A perspective on the clinical translation of scaffolds for tissue engineering. Ann Biomed Eng. 2015 Mar; 43(3):641-56. Webber MJ, Khan OF, Sydlik SA, Tang BC, Langer R. PMID: 25201605.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimals
    38. Intraperitoneal delivery of paclitaxel by poly(ether-anhydride) microspheres effectively suppresses tumor growth in a murine metastatic ovarian cancer model. Drug Deliv Transl Res. 2014 Apr 01; 4(2):203-9. Yang M, Yu T, Wood J, Wang YY, Tang BC, Zeng Q, Simons BW, Fu J, Chuang CM, Lai SK, Wu TC, Hung CF, Hanes J. PMID: 24816829.
      View in: PubMed   Mentions: 4     Fields:    
    39. Lipid-like nanomaterials for simultaneous gene expression and silencing in vivo. Adv Healthc Mater. 2014 Sep; 3(9):1392-7. Dong Y, Eltoukhy AA, Alabi CA, Khan OF, Veiseh O, Dorkin JR, Sirirungruang S, Yin H, Tang BC, Pelet JM, Chen D, Gu Z, Xue Y, Langer R, Anderson DG. PMID: 24623658.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    40. Vaginal delivery of paclitaxel via nanoparticles with non-mucoadhesive surfaces suppresses cervical tumor growth. Adv Healthc Mater. 2014 Jul; 3(7):1044-52. Yang M, Yu T, Wang YY, Lai SK, Zeng Q, Miao B, Tang BC, Simons BW, Ensign LM, Liu G, Chan KW, Juang CY, Mert O, Wood J, Fu J, McMahon MT, Wu TC, Hung CF, Hanes J. PMID: 24339398.
      View in: PubMed   Mentions: 26     Fields:    Translation:Animals
    41. Microneedle electrodes toward an amperometric glucose-sensing smart patch. Adv Healthc Mater. 2014 Mar; 3(3):338-42. Invernale MA, Tang BC, York RL, Le L, Hou DY, Anderson DG. PMID: 24039157.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    42. Glucose-responsive microgels integrated with enzyme nanocapsules for closed-loop insulin delivery. ACS Nano. 2013 Aug 27; 7(8):6758-66. Gu Z, Dang TT, Ma M, Tang BC, Cheng H, Jiang S, Dong Y, Zhang Y, Anderson DG. PMID: 23834678.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
    43. Mucus-penetrating nanoparticles for vaginal drug delivery protect against herpes simplex virus. Sci Transl Med. 2012 Jun 13; 4(138):138ra79. Ensign LM, Tang BC, Wang YY, Tse TA, Hoen T, Cone R, Hanes J. PMID: 22700955.
      View in: PubMed   Mentions: 95     Fields:    Translation:HumansAnimalsCells
    44. Real-time gene delivery vector tracking in the endo-lysosomal pathway of live cells. Microsc Res Tech. 2012 May; 75(5):691-7. Suh J, An Y, Tang BC, Dempsey C, Huang F, Hanes J. PMID: 22095650.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    45. N-acetylcysteine enhances cystic fibrosis sputum penetration and airway gene transfer by highly compacted DNA nanoparticles. Mol Ther. 2011 Nov; 19(11):1981-9. Suk JS, Boylan NJ, Trehan K, Tang BC, Schneider CS, Lin JM, Boyle MP, Zeitlin PL, Lai SK, Cooper MJ, Hanes J. PMID: 21829177.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    46. Development of delivery methods for carbohydrate-based drugs: controlled release of biologically-active short chain fatty acid-hexosamine analogs. Glycoconj J. 2010 May; 27(4):445-59. Aich U, Meledeo MA, Sampathkumar SG, Fu J, Jones MB, Weier CA, Chung SY, Tang BC, Yang M, Hanes J, Yarema KJ. PMID: 20458533.
      View in: PubMed   Mentions: 6     Fields:    
    47. Pentastatin-1, a collagen IV derived 20-mer peptide, suppresses tumor growth in a small cell lung cancer xenograft model. BMC Cancer. 2010 Feb 01; 10:29. Koskimaki JE, Karagiannis ED, Tang BC, Hammers H, Watkins DN, Pili R, Popel AS. PMID: 20122172.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    48. Biodegradable polymer nanoparticles that rapidly penetrate the human mucus barrier. Proc Natl Acad Sci U S A. 2009 Nov 17; 106(46):19268-73. Tang BC, Dawson M, Lai SK, Wang YY, Suk JS, Yang M, Zeitlin P, Boyle MP, Fu J, Hanes J. PMID: 19901335.
      View in: PubMed   Mentions: 103     Fields:    Translation:Humans
    49. Enhanced efficacy of local etoposide delivery by poly(ether-anhydride) particles against small cell lung cancer in vivo. Biomaterials. 2010 Jan; 31(2):339-44. Tang BC, Fu J, Watkins DN, Hanes J. PMID: 19796810.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    50. PEGylation of nanoparticles improves their cytoplasmic transport. Int J Nanomedicine. 2007; 2(4):735-41. Suh J, Choy KL, Lai SK, Suk JS, Tang BC, Prabhu S, Hanes J. PMID: 18203439.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    51. Protein disulfide isomerase, but not binding protein, overexpression enhances secretion of a non-disulfide-bonded protein in yeast. Biotechnol Bioeng. 2004 Feb 05; 85(3):340-50. Smith JD, Tang BC, Robinson AS. PMID: 14748090.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
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