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Michelle Arkin, PhD

Title(s)Professor, Pharmaceutical Chemistry
SchoolSchool of Pharmacy
Address1700 4th St
San Francisco CA 94158
Phone415-514-4313
ORCID ORCID Icon0000-0002-9366-6770 Additional info
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    Collapse Biography 
    Collapse Education and Training
    Bryn Mawr College, Pennsylvania, USAAB06/1990Chemistry
    Caltech, California, USAPhD02/1997Chemistry
    Genentech, California, USA6/1998Protein Engineering
    Collapse Awards and Honors
    Bryn Mawr College1989Shippen Science Scholarship
    Bryn Mawr College1989Dorothy Nepper Marshall Fellowship
    Armed Force1989Armed Forces Communications and Electronics Association Scholarship
    Bryn Mawr College1990  - 1991European Traveling Fellowship
    General Electric Foundation1991  - 1992Blodgett Fellowship
    National Science Foundation 1992  - 1995Predoctoral Fellowship
    National Institutes of Health 1995  - 1997National Institutes of Health Traineeship
    Daymon Runyon – Walter Winchell Cancer Research Foundation 1997  - 1999Daymon Runyon – Walter Winchell Cancer Research Foundation Postdoctoral Fellowship
    SLAS2013Finalist, SLAS Innovation Award

    Collapse Overview 
    Collapse Overview
    Michelle’s lab develops innovative approaches to screen for chemical tools and drug leads, using biophysical approaches like fragment-based drug discovery and biological approaches including high-content imaging with primary cells and organisms. Our goal is to demonstrate ‘druggability’ of new target classes and to use our compounds to discover new targets for drug discovery. Areas of interest include protein-protein interactions, allosteric and scaffolding sites in enzymes, and orphan and neglected diseases. Michelle is Associate Director of the Small Molecule Discovery Center, a collaborative research and core lab that includes a high-throughput screening facility (smdc.ucsf.edu).

    Collapse ORNG Applications 
    Collapse Websites
    Collapse In The News

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Fragment-based Differential Targeting of PPI Stabilizer Interfaces. J Med Chem. 2020 Jun 05. Guillory X, Wolter M, Leysen S, Neves JF, Kuusk A, Genet S, Somsen B, Morrow J, Rivers E, van Beek L, Patel J, Goodnow R, Schoenherr H, Fuller N, Cao Q, Doveston RG, Brunsveld L, Arkin MR, Castaldi MP, Boyd H, Landrieu I, Chen H, Ottmann C. PMID: 32501690.
      View in: PubMed   Mentions:    Fields:    
    2. Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation. Nat Immunol. 2020 05; 21(5):513-524. Mendiola AS, Ryu JK, Bardehle S, Meyer-Franke A, Ang KK, Wilson C, Baeten KM, Hanspers K, Merlini M, Thomas S, Petersen MA, Williams A, Thomas R, Rafalski VA, Meza-Acevedo R, Tognatta R, Yan Z, Pfaff SJ, Machado MR, Bedard C, Rios Coronado PE, Jiang X, Wang J, Pleiss MA, Green AJ, Zamvil SS, Pico AR, Bruneau BG, Arkin MR, Akassoglou K. PMID: 32284594.
      View in: PubMed   Mentions:    Fields:    
    3. Stress Resistance Screen in a Human Primary Cell Line Identifies Small Molecules That Affect Aging Pathways and Extend Caenorhabditis elegans' Lifespan. G3 (Bethesda). 2020 02 06; 10(2):849-862. Zhang P, Zhai Y, Cregg J, Ang KK, Arkin M, Kenyon C. PMID: 31879284.
      View in: PubMed   Mentions:    Fields:    
    4. Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy. Mol Neurodegener. 2020 01 06; 15(1):2. Chen X, Li Y, Wang C, Tang Y, Mok SA, Tsai RM, Rojas JC, Karydas A, Miller BL, Boxer AL, Gestwicki JE, Arkin M, Cuervo AM, Gan L. PMID: 31906970.
      View in: PubMed   Mentions:    Fields:    
    5. Identification of Plasmodium dipeptidyl aminopeptidase allosteric inhibitors by high throughput screening. PLoS One. 2019; 14(12):e0226270. Sanchez MI, de Vries LE, Lehmann C, Lee JT, Ang KK, Wilson C, Chen S, Arkin MR, Bogyo M, Deu E. PMID: 31851699.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    6. A Cell-Based Renilla Luminescence Reporter Plasmid Assay for High-Throughput Screening to Identify Novel FDA-Approved Drug Inhibitors of HPV-16 Infection. SLAS Discov. 2020 01; 25(1):79-86. Walhart T, Isaacson-Wechsler E, Ang KH, Arkin M, Tugizov S, Palefsky JM. PMID: 31361520.
      View in: PubMed   Mentions:    Fields:    
    7. Specificity for latent C termini links the E3 ubiquitin ligase CHIP to caspases. Nat Chem Biol. 2019 08; 15(8):786-794. Ravalin M, Theofilas P, Basu K, Opoku-Nsiah KA, Assimon VA, Medina-Cleghorn D, Chen YF, Bohn MF, Arkin M, Grinberg LT, Craik CS, Gestwicki JE. PMID: 31320752.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    8. TAU-MEDIATED CELL DEATH MECHANISMS IN MAPT V337M IPSC-DERIVED HUMAN NEURONS. Alzheimer's & Dementia. 2019 Jul 1; 15(7):p1006. Panos Theofilas, Mifrah Hayath, Chao Wang, David Butler, Salome McAllen, Michelle Arkin, Jason Gestwicki, Ana Maria Cuervo, Rakez Kayed, Celeste M. Karch, Sally Temple, Li Gan, Lea T. Grinberg. .
      View in: Publisher Site   Mentions:
    9. Modulating protein-protein interaction networks in protein homeostasis. Curr Opin Chem Biol. 2019 06; 50:55-65. Zhong M, Lee GM, Sijbesma E, Ottmann C, Arkin MR. PMID: 30913483.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    10. Site-Directed Fragment-Based Screening for the Discovery of Protein-Protein Interaction Stabilizers. J Am Chem Soc. 2019 02 27; 141(8):3524-3531. Sijbesma E, Hallenbeck KK, Leysen S, de Vink PJ, Skóra L, Jahnke W, Brunsveld L, Arkin MR, Ottmann C. PMID: 30707565.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    11. Guidelines for DNA recombination and repair studies: Mechanistic assays of DNA repair processes. Microb Cell. 2019 Jan 07; 6(1):65-101. Klein HL, Ang KKH, Arkin MR, Beckwitt EC, Chang YH, Fan J, Kwon Y, Morten MJ, Mukherjee S, Pambos OJ, El Sayyed H, Thrall ES, Vieira-da-Rocha JP, Wang Q, Wang S, Yeh HY, Biteen JS, Chi P, Heyer WD, Kapanidis AN, Loparo JJ, Strick TR, Sung P, Van Houten B, Niu H, Rothenberg E. PMID: 30652106.
      View in: PubMed   Mentions:
    12. Functional Assessment of 2,177 U.S. and International Drugs Identifies the Quinoline Nitroxoline as a Potent Amoebicidal Agent against the Pathogen Balamuthia mandrillaris. mBio. 2018 10 30; 9(5). Laurie MT, White CV, Retallack H, Wu W, Moser MS, Sakanari JA, Ang K, Wilson C, Arkin MR, DeRisi JL. PMID: 30377287.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    13. Fibrin-targeting immunotherapy protects against neuroinflammation and neurodegeneration. Nat Immunol. 2018 11; 19(11):1212-1223. Ryu JK, Rafalski VA, Meyer-Franke A, Adams RA, Poda SB, Rios Coronado PE, Pedersen LØ, Menon V, Baeten KM, Sikorski SL, Bedard C, Hanspers K, Bardehle S, Mendiola AS, Davalos D, Machado MR, Chan JP, Plastira I, Petersen MA, Pfaff SJ, Ang KK, Hallenbeck KK, Syme C, Hakozaki H, Ellisman MH, Swanson RA, Zamvil SS, Arkin MR, Zorn SH, Pico AR, Mucke L, Freedman SB, Stavenhagen JB, Nelson RB, Akassoglou K. PMID: 30323343.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    14. Optimization of Phenyl Indole Inhibitors of the AAA+ ATPase p97. ACS Med Chem Lett. 2018 Nov 08; 9(11):1075-1081. LaPorte MG, Burnett JC, Colombo R, Bulfer SL, Alverez C, Chou TF, Neitz RJ, Green N, Moore WJ, Yue Z, Li S, Arkin MR, Wipf P, Huryn DM. PMID: 30429948.
      View in: PubMed   Mentions:
    15. A Genetic Interaction Map of Insulin Production Identifies Mfi as an Inhibitor of Mitochondrial Fission. Endocrinology. 2018 09 01; 159(9):3321-3330. Lee J, Pappalardo Z, Chopra DG, Hennings TG, Vaughn I, Lan C, Choe JJ, Ang K, Chen S, Arkin M, McManus MT, German MS, Ku GM. PMID: 30059978.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    16. Octopamine signaling in the metazoan pathogen Schistosoma mansoni: localization, small-molecule screening and opportunities for drug development. Dis Model Mech. 2018 07 30; 11(7). El-Sakkary N, Chen S, Arkin MR, Caffrey CR, Ribeiro P. PMID: 29925529.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    17. Assay Guidance Manual: Quantitative Biology and Pharmacology in Preclinical Drug Discovery. Clin Transl Sci. 2018 09; 11(5):461-470. Coussens NP, Sittampalam GS, Guha R, Brimacombe K, Grossman A, Chung TDY, Weidner JR, Riss T, Trask OJ, Auld D, Dahlin JL, Devanaryan V, Foley TL, McGee J, Kahl SD, Kales SC, Arkin M, Baell J, Bejcek B, Gal-Edd N, Glicksman M, Haas JV, Iversen PW, Hoeppner M, Lathrop S, Sayers E, Liu H, Trawick B, McVey J, Lemmon VP, Li Z, McManus O, Minor L, Napper A, Wildey MJ, Pacifici R, Chin WW, Xia M, Xu X, Lal-Nag M, Hall MD, Michael S, Inglese J, Simeonov A, Austin CP. PMID: 29877628.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    18. Small-Molecule Screening for Genetic Diseases. Annu Rev Genomics Hum Genet. 2018 08 31; 19:263-288. Markossian S, Ang KK, Wilson CG, Arkin MR. PMID: 29799800.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    19. EXTH-55. REPURPOSING THERAPEUTICS IN PATIENT-DERIVED GLIOMAS AND AN IDH1 MUTANT GLIOMA MODEL. Neuro-Oncology. 2017 Nov 6; 19(suppl_6):vi84-vi85. Christin Schmidt, Steven Chen, Shirin IIkhanizadeh, Hanna Sabelstrom, Edith Yuan, Andy Ding, William Weiss, Mitchel S Berger, Michelle Arkin, Anders Persson. .
      View in: Publisher Site   Mentions:
    20. USP7 small-molecule inhibitors interfere with ubiquitin binding. Nature. 2017 10 26; 550(7677):534-538. Kategaya L, Di Lello P, Rougé L, Pastor R, Clark KR, Drummond J, Kleinheinz T, Lin E, Upton JP, Prakash S, Heideker J, McCleland M, Ritorto MS, Alessi DR, Trost M, Bainbridge TW, Kwok MCM, Ma TP, Stiffler Z, Brasher B, Tang Y, Jaishankar P, Hearn BR, Renslo AR, Arkin MR, Cohen F, Yu K, Peale F, Gnad F, Chang MT, Klijn C, Blackwood E, Martin SE, Forrest WF, Ernst JA, Ndubaku C, Wang X, Beresini MH, Tsui V, Schwerdtfeger C, Blake RA, Murray J, Maurer T, Wertz IE. PMID: 29045385.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    21. A Liquid Chromatography/Mass Spectrometry Method for Screening Disulfide Tethering Fragments. SLAS Discov. 2018 02; 23(2):183-192. Hallenbeck KK, Davies JL, Merron C, Ogden P, Sijbesma E, Ottmann C, Renslo AR, Wilson C, Arkin MR. PMID: 28945980.
      View in: PubMed   Mentions: 1     Fields:    
    22. Chemical Biology as a Driver of Innovation in Cancer Research and Drug Discovery. Cell Chem Biol. 2017 09 21; 24(9):1057. Kostic M, Arkin M. PMID: 28938086.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    23. Probing the correlation of neuronal loss, neurofibrillary tangles, and cell death markers across the Alzheimer's disease Braak stages: a quantitative study in humans. Neurobiol Aging. 2018 01; 61:1-12. Theofilas P, Ehrenberg AJ, Nguy A, Thackrey JM, Dunlop S, Mejia MB, Alho AT, Paraizo Leite RE, Rodriguez RD, Suemoto CK, Nascimento CF, Chin M, Medina-Cleghorn D, Cuervo AM, Arkin M, Seeley WW, Miller BL, Nitrini R, Pasqualucci CA, Filho WJ, Rueb U, Neuhaus J, Heinsen H, Grinberg LT. PMID: 29031088.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    24. Applying Biophysical and Biochemical Methods to the Discovery of Allosteric Modulators of the AAA ATPase p97. Applied Biophysics for Drug Discovery. 2017 Aug 10; 217-240. Stacie L. Bulfer, Michelle R. Arkin. .
      View in: Publisher Site   Mentions:
    25. Joining Forces: The Chemical Biology-Medicinal Chemistry Continuum. Cell Chem Biol. 2017 Sep 21; 24(9):1058-1065. Plowright AT, Ottmann C, Arkin M, Auberson YP, Timmerman H, Waldmann H. PMID: 28602761.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    26. High-Throughput Screening To Identify Potent and Specific Inhibitors of Microbial Sulfate Reduction. Environ Sci Technol. 2017 Jun 20; 51(12):7278-7285. Carlson HK, Mullan MR, Mosqueda LA, Chen S, Arkin MR, Coates JD. PMID: 28492331.
      View in: PubMed   Mentions: 1     Fields:    Translation:CellsPHPublic Health
    27. A threonine turnstile defines a dynamic amphiphilic binding motif in the AAA ATPase p97 allosteric binding site. Org Biomol Chem. 2017 May 16; 15(19):4096-4114. Burnett JC, Lim C, Peyser BD, Samankumara LP, Kovaliov M, Colombo R, Bulfer SL, LaPorte MG, Hermone AR, McGrath CF, Arkin MR, Gussio R, Huryn DM, Wipf P. PMID: 28352916.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    28. A Whole-Genome RNA Interference Screen Reveals a Role for Spry2 in Insulin Transcription and the Unfolded Protein Response. Diabetes. 2017 06; 66(6):1703-1712. Pappalardo Z, Gambhir Chopra D, Hennings TG, Richards H, Choe J, Yang K, Baeyens L, Ang K, Chen S, Arkin M, German MS, McManus MT, Ku GM. PMID: 28246293.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    29. Targeting Non-Catalytic Cysteine Residues Through Structure-Guided Drug Discovery. Curr Top Med Chem. 2017; 17(1):4-15. Hallenbeck KK, Turner DM, Renslo AR, Arkin MR. PMID: 27449257.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    30. Identification of Inhibitors of the Association of ZAP-70 with the T Cell Receptor by High-Throughput Screen. SLAS Discov. 2017 03; 22(3):324-331. Visperas PR, Wilson CG, Winger JA, Yan Q, Lin K, Arkin MR, Weiss A, Kuriyan J. PMID: 27932698.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    31. A High-Content Larval Zebrafish Brain Imaging Method for Small Molecule Drug Discovery. PLoS One. 2016; 11(10):e0164645. Liu H, Chen S, Huang K, Kim J, Mo H, Iovine R, Gendre J, Pascal P, Li Q, Sun Y, Dong Z, Arkin M, Guo S, Huang B. PMID: 27732643.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    32. Ceapins are a new class of unfolded protein response inhibitors, selectively targeting the ATF6a branch. Elife. 2016 07 20; 5. Gallagher CM, Garri C, Cain EL, Ang KK, Wilson CG, Chen S, Hearn BR, Jaishankar P, Aranda-Diaz A, Arkin MR, Renslo AR, Walter P. PMID: 27435960.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    33. p97 Disease Mutations Modulate Nucleotide-Induced Conformation to Alter Protein-Protein Interactions. ACS Chem Biol. 2016 08 19; 11(8):2112-6. Bulfer SL, Chou TF, Arkin MR. PMID: 27267671.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    34. 2.3 Å resolution cryo-EM structure of human p97 and mechanism of allosteric inhibition. Science. 2016 Feb 19; 351(6275):871-5. Banerjee S, Bartesaghi A, Merk A, Rao P, Bulfer SL, Yan Y, Green N, Mroczkowski B, Neitz RJ, Wipf P, Falconieri V, Deshaies RJ, Milne JL, Huryn D, Arkin M, Subramaniam S. PMID: 26822609.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansCells
    35. Making FBDD Work in Academia. Fragment-based Drug Discovery Lessons and Outlook. 2016 Jan 11; 223-246. Stacie L. Bulfer, Frantz L. Jean-Francois, Michelle R. Arkin. .
      View in: Publisher Site   Mentions:
    36. Allosteric Indole Amide Inhibitors of p97: Identification of a Novel Probe of the Ubiquitin Pathway. ACS Med Chem Lett. 2016 Feb 11; 7(2):182-7. Alverez C, Bulfer SL, Chakrasali R, Chimenti MS, Deshaies RJ, Green N, Kelly M, LaPorte MG, Lewis TS, Liang M, Moore WJ, Neitz RJ, Peshkov VA, Walters MA, Zhang F, Arkin MR, Wipf P, Huryn DM. PMID: 26985295.
      View in: PubMed   Mentions:
    37. A gene-expression screen identifies a non-toxic sumoylation inhibitor that mimics SUMO-less human LRH-1 in liver. Elife. 2015 Dec 11; 4. Suzawa M, Miranda DA, Ramos KA, Ang KK, Faivre EJ, Wilson CG, Caboni L, Arkin MR, Kim YS, Fletterick RJ, Diaz A, Schneekloth JS, Ingraham HA. PMID: 26653140.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    38. Covalent targeting of acquired cysteines in cancer. Curr Opin Chem Biol. 2016 Feb; 30:61-67. Visscher M, Arkin MR, Dansen TB. PMID: 26629855.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    39. Structure-Activity Study of Bioisosteric Trifluoromethyl and Pentafluorosulfanyl Indole Inhibitors of the AAA ATPase p97. ACS Med Chem Lett. 2015 Dec 10; 6(12):1225-30. Alverez C, Arkin MR, Bulfer SL, Colombo R, Kovaliov M, LaPorte MG, Lim C, Liang M, Moore WJ, Neitz RJ, Yan Y, Yue Z, Huryn DM, Wipf P. PMID: 26713109.
      View in: PubMed   Mentions:
    40. Tackling reproducibility in academic preclinical drug discovery. Nat Rev Drug Discov. 2015 11; 14(11):733-4. Frye SV, Arkin MR, Arrowsmith CH, Conn PJ, Glicksman MA, Hull-Ryde EA, Slusher BS. PMID: 26388229.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimals
    41. Utilizing Chemical Genomics to Identify Cytochrome b as a Novel Drug Target for Chagas Disease. PLoS Pathog. 2015 Jul; 11(7):e1005058. Khare S, Roach SL, Barnes SW, Hoepfner D, Walker JR, Chatterjee AK, Neitz RJ, Arkin MR, McNamara CW, Ballard J, Lai Y, Fu Y, Molteni V, Yeh V, McKerrow JH, Glynne RJ, Supek F. PMID: 26186534.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    42. Machine Learning Models and Pathway Genome Data Base for Trypanosoma cruzi Drug Discovery. PLoS Negl Trop Dis. 2015; 9(6):e0003878. Ekins S, de Siqueira-Neto JL, McCall LI, Sarker M, Yadav M, Ponder EL, Kallel EA, Kellar D, Chen S, Arkin M, Bunin BA, McKerrow JH, Talcott C. PMID: 26114876.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    43. Tetrafluorophenoxymethyl ketone cruzain inhibitors with improved pharmacokinetic properties as therapeutic leads for Chagas' disease. Bioorg Med Chem Lett. 2015 Nov 01; 25(21):4834-4837. Neitz RJ, Bryant C, Chen S, Gut J, Hugo Caselli E, Ponce S, Chowdhury S, Xu H, Arkin MR, Ellman JA, Renslo AR. PMID: 26144347.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    44. Altered cofactor regulation with disease-associated p97/VCP mutations. Proc Natl Acad Sci U S A. 2015 Apr 07; 112(14):E1705-14. Zhang X, Gui L, Zhang X, Bulfer SL, Sanghez V, Wong DE, Lee Y, Lehmann L, Lee JS, Shih PY, Lin HJ, Iacovino M, Weihl CC, Arkin MR, Wang Y, Chou TF. PMID: 25775548.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    45. Tethering in RNA: an RNA-binding fragment discovery tool. Molecules. 2015 Mar 04; 20(3):4148-61. Tran K, Arkin MR, Beal PA. PMID: 25749683.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    46. Repurposing auranofin as a lead candidate for treatment of lymphatic filariasis and onchocerciasis. PLoS Negl Trop Dis. 2015 Feb; 9(2):e0003534. Bulman CA, Bidlow CM, Lustigman S, Cho-Ngwa F, Williams D, Rascón AA, Tricoche N, Samje M, Bell A, Suzuki B, Lim KC, Supakorndej N, Supakorndej P, Wolfe AR, Knudsen GM, Chen S, Wilson C, Ang KH, Arkin M, Gut J, Franklin C, Marcellino C, McKerrow JH, Debnath A, Sakanari JA. PMID: 25700363.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    47. A Fragment-Based Ligand Screen Against Part of a Large Protein Machine: The ND1 Domains of the AAA+ ATPase p97/VCP. J Biomol Screen. 2015 Jul; 20(6):788-800. Chimenti MS, Bulfer SL, Neitz RJ, Renslo AR, Jacobson MP, James TL, Arkin MR, Kelly MJ. PMID: 25690569.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    48. Biophysical methods for identifying fragment-based inhibitors of protein-protein interactions. Methods Mol Biol. 2015; 1278:587-613. Pfaff SJ, Chimenti MS, Kelly MJ, Arkin MR. PMID: 25859978.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    49. Modification by covalent reaction or oxidation of cysteine residues in the tandem-SH2 domains of ZAP-70 and Syk can block phosphopeptide binding. Biochem J. 2015 Jan 01; 465(1):149-61. Visperas PR, Winger JA, Horton TM, Shah NH, Aum DJ, Tao A, Barros T, Yan Q, Wilson CG, Arkin MR, Weiss A, Kuriyan J. PMID: 25287889.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    50. A small-molecule mimic of a peptide docking motif inhibits the protein kinase PDK1. Proc Natl Acad Sci U S A. 2014 Dec 30; 111(52):18590-5. Rettenmaier TJ, Sadowsky JD, Thomsen ND, Chen SC, Doak AK, Arkin MR, Wells JA. PMID: 25518860.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    51. Lead identification to clinical candidate selection: drugs for Chagas disease. J Biomol Screen. 2015 Jan; 20(1):101-11. Neitz RJ, Chen S, Supek F, Yeh V, Kellar D, Gut J, Bryant C, Gallardo-Godoy A, Molteni V, Roach SL, Khare S, Stinson M, Chatterjee AK, Robertson S, Renslo AR, Arkin M, Glynne R, McKerrow J, Siqueira-Neto JL. PMID: 25281737.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    52. Small-molecule inhibitors of protein-protein interactions: progressing toward the reality. Chem Biol. 2014 Sep 18; 21(9):1102-14. Arkin MR, Tang Y, Wells JA. PMID: 25237857.
      View in: PubMed   Mentions: 176     Fields:    Translation:HumansCells
    53. Screening for noise in gene expression identifies drug synergies. Science. 2014 Jun 20; 344(6190):1392-6. Dar RD, Hosmane NN, Arkin MR, Siliciano RF, Weinberger LS. PMID: 24903562.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansCells
    54. Specific inhibition of p97/VCP ATPase and kinetic analysis demonstrate interaction between D1 and D2 ATPase domains. J Mol Biol. 2014 Jul 29; 426(15):2886-99. Chou TF, Bulfer SL, Weihl CC, Li K, Lis LG, Walters MA, Schoenen FJ, Lin HJ, Deshaies RJ, Arkin MR. PMID: 24878061.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    55. UCSF Small Molecule Discovery Center: innovation, collaboration and chemical biology in the Bay Area. Comb Chem High Throughput Screen. 2014 May; 17(4):333-42. Arkin MR, Ang KK, Chen S, Davies J, Merron C, Tang Y, Wilson CG, Renslo AR. PMID: 24661212.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    56. Inhibiting caspase-6 activation and catalytic activity for neurodegenerative diseases. Curr Top Med Chem. 2014; 14(3):319-25. Flygare JA, Arkin MR. PMID: 24283214.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    57. Inside Cover: Tailoring Small Molecules for an Allosteric Site on Procaspase-6 (ChemMedChem 1/2014). ChemMedChem. 2014 Jan 1; 9(1):2-2. Jeremy Murray, Anthony M. Giannetti, Micah Steffek, Paul Gibbons, Brian R. Hearn, Frederick Cohen, Christine Tam, Christine Pozniak, Brandon Bravo, Joe Lewcock, Priyadarshini Jaishankar, Cuong Q. Ly, Xianrui Zhao, Yinyan Tang, Preeti Chugha, Michelle R. Arkin, John Flygare, Adam R. Renslo. .
      View in: Publisher Site   Mentions:
    58. Probing structural adaptivity at PPI interfaces with small molecules. Drug Discov Today Technol. 2013 Dec; 10(4):e501-8. Wilson CG, Arkin MR. PMID: 24451641.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    59. Tailoring small molecules for an allosteric site on procaspase-6. ChemMedChem. 2014 Jan; 9(1):73-7, 2. Murray J, Giannetti AM, Steffek M, Gibbons P, Hearn BR, Cohen F, Tam C, Pozniak C, Bravo B, Lewcock J, Jaishankar P, Ly CQ, Zhao X, Tang Y, Chugha P, Arkin MR, Flygare J, Renslo AR. PMID: 24259468.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    60. Bringing together the academic drug discovery community. Nat Rev Drug Discov. 2013 Nov; 12(11):811-2. Slusher BS, Conn PJ, Frye S, Glicksman M, Arkin M. PMID: 24172316.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    61. Imaging-based chemical screening reveals activity-dependent neural differentiation of pluripotent stem cells. Elife. 2013 Sep 10; 2:e00508. Sun Y, Dong Z, Jin T, Ang KH, Huang M, Haston KM, Peng J, Zhong TP, Finkbeiner S, Weiss WA, Arkin MR, Jan LY, Guo S. PMID: 24040509.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    62. A high-throughput functional screen identifies small molecule regulators of temperature- and mechano-sensitive K2P channels. ACS Chem Biol. 2013 Aug 16; 8(8):1841-51. Bagriantsev SN, Ang KH, Gallardo-Godoy A, Clark KA, Arkin MR, Renslo AR, Minor DL. PMID: 23738709.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    63. Pharmacological brake-release of mRNA translation enhances cognitive memory. Elife. 2013 May 28; 2:e00498. Sidrauski C, Acosta-Alvear D, Khoutorsky A, Vedantham P, Hearn BR, Li H, Gamache K, Gallagher CM, Ang KK, Wilson C, Okreglak V, Ashkenazi A, Hann B, Nader K, Arkin MR, Renslo AR, Sonenberg N, Walter P. PMID: 23741617.
      View in: PubMed   Mentions: 138     Fields:    Translation:HumansAnimalsCells
    64. Chemical-biological characterization of a cruzain inhibitor reveals a second target and a mammalian off-target. Beilstein J Org Chem. 2013; 9:15-25. Choy JW, Bryant C, Calvet CM, Doyle PS, Gunatilleke SS, Leung SS, Ang KK, Chen S, Gut J, Oses-Prieto JA, Johnston JB, Arkin MR, Burlingame AL, Taunton J, Jacobson MP, McKerrow JM, Podust LM, Renslo AR. PMID: 23400640.
      View in: PubMed   Mentions:
    65. Protein–Protein Interactions – Inhibition. Encyclopedia of Biophysics. 2013 Jan 1; 2093-2098. Preeti Chugha, Michelle Arkin. .
      View in: Publisher Site   Mentions:
    66. Mechanistic and structural understanding of uncompetitive inhibitors of caspase-6. PLoS One. 2012; 7(12):e50864. Heise CE, Murray J, Augustyn KE, Bravo B, Chugha P, Cohen F, Giannetti AM, Gibbons P, Hannoush RN, Hearn BR, Jaishankar P, Ly CQ, Shah K, Stanger K, Steffek M, Tang Y, Zhao X, Lewcock JW, Renslo AR, Flygare J, Arkin MR. PMID: 23227217.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    67. Small molecule inhibitors of Smoothened ciliary localization and ciliogenesis. Proc Natl Acad Sci U S A. 2012 Aug 21; 109(34):13644-9. Wu VM, Chen SC, Arkin MR, Reiter JF. PMID: 22864913.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    68. Diverse inhibitor chemotypes targeting Trypanosoma cruzi CYP51. PLoS Negl Trop Dis. 2012; 6(7):e1736. Gunatilleke SS, Calvet CM, Johnston JB, Chen CK, Erenburg G, Gut J, Engel JC, Ang KK, Mulvaney J, Chen S, Arkin MR, McKerrow JH, Podust LM. PMID: 22860142.
      View in: PubMed   Mentions: 25     Fields:    Translation:Cells
    69. Analysis of high-throughput screening assays using cluster enrichment. Stat Med. 2012 Dec 30; 31(30):4175-89. Pu M, Hayashi T, Cottam H, Mulvaney J, Arkin M, Corr M, Carson D, Messer K. PMID: 22763983.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    70. Novel cruzain inhibitors for the treatment of Chagas' disease. Chem Biol Drug Des. 2012 Sep; 80(3):398-405. Rogers KE, Keränen H, Durrant JD, Ratnam J, Doak A, Arkin MR, McCammon JA. PMID: 22613098.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    71. A high-throughput drug screen for Entamoeba histolytica identifies a new lead and target. Nat Med. 2012 Jun; 18(6):956-60. Debnath A, Parsonage D, Andrade RM, He C, Cobo ER, Hirata K, Chen S, García-Rivera G, Orozco E, Martínez MB, Gunatilleke SS, Barrios AM, Arkin MR, Poole LB, McKerrow JH, Reed SL. PMID: 22610278.
      View in: PubMed   Mentions: 86     Fields:    Translation:Animals
    72. Discovery and Development of Potent LFA-1/ICAM-1 Antagonist SAR 1118 as an Ophthalmic Solution for Treating Dry Eye. ACS Med Chem Lett. 2012 Mar 08; 3(3):203-6. Zhong M, Gadek TR, Bui M, Shen W, Burnier J, Barr KJ, Hanan EJ, Oslob JD, Yu CH, Zhu J, Arkin MR, Evanchik MJ, Flanagan WM, Hoch U, Hyde J, Prabhu S, Silverman JA, Wright J. PMID: 24900456.
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    73. Quantification and clustering of phenotypic screening data using time-series analysis for chemotherapy of schistosomiasis. BMC Genomics. 2012; 13 Suppl 1:S4. Lee H, Moody-Davis A, Saha U, Suzuki BM, Asarnow D, Chen S, Arkin M, Caffrey CR, Singh R. PMID: 22369037.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    74. Structural and enzymatic insights into caspase-2 protein substrate recognition and catalysis. J Biol Chem. 2011 Sep 30; 286(39):34147-54. Tang Y, Wells JA, Arkin MR. PMID: 21828056.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    75. A screen against Leishmania intracellular amastigotes: comparison to a promastigote screen and identification of a host cell-specific hit. PLoS Negl Trop Dis. 2011 Jul; 5(7):e1253. De Muylder G, Ang KK, Chen S, Arkin MR, Engel JC, McKerrow JH. PMID: 21811648.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    76. Mining a cathepsin inhibitor library for new antiparasitic drug leads. PLoS Negl Trop Dis. 2011 May 03; 5(5):e1023. Ang KK, Ratnam J, Gut J, Legac J, Hansell E, Mackey ZB, Skrzypczynska KM, Debnath A, Engel JC, Rosenthal PJ, McKerrow JH, Arkin MR, Renslo AR. PMID: 21572521.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    77. A high-throughput turbidometric assay for screening inhibitors of Leishmania major protein disulfide isomerase. J Biomol Screen. 2011 Jun; 16(5):545-51. Ben Khalaf N, De Muylder G, Ratnam J, Kean-Hooi Ang K, Arkin M, McKerrow J, Chenik M. PMID: 21441416.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    78. An image-based assay for high throughput screening of Giardia lamblia. J Microbiol Methods. 2011 Mar; 84(3):398-405. Gut J, Ang KK, Legac J, Arkin MR, Rosenthal PJ, McKerrow JH. PMID: 21262276.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    79. Small-molecule inhibitors of IL-2/IL-2R: lessons learned and applied. Curr Top Microbiol Immunol. 2011; 348:25-59. Wilson CG, Arkin MR. PMID: 20703966.
      View in: PubMed   Mentions: 18     Fields:    Translation:Cells
    80. Structure-activity relationship (SAR) of the a-amino acid residue of potent tetrahydroisoquinoline (THIQ)-derived LFA-1/ICAM-1 antagonists. Bioorg Med Chem Lett. 2011 Jan 01; 21(1):307-10. Zhong M, Hanan EJ, Shen W, Bui M, Arkin MR, Barr KJ, Evanchik MJ, Hoch U, Hyde J, Martell JR, Oslob JD, Paulvannan K, Prabhu S, Silverman JA, Wright J, Yu CH, Zhu J, Flanagan WM. PMID: 21109434.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    81. Discovery of tetrahydroisoquinoline (THIQ) derivatives as potent and orally bioavailable LFA-1/ICAM-1 antagonists. Bioorg Med Chem Lett. 2010 Sep 01; 20(17):5269-73. Zhong M, Shen W, Barr KJ, Arbitrario JP, Arkin MR, Bui M, Chen T, Cunningham BC, Evanchik MJ, Hanan EJ, Hoch U, Huen K, Hyde J, Kumer JL, Lac T, Lawrence CE, Martell JR, Oslob JD, Paulvannan K, Prabhu S, Silverman JA, Wright J, Yu CH, Zhu J, Flanagan WM. PMID: 20655213.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    82. Image-based high-throughput drug screening targeting the intracellular stage of Trypanosoma cruzi, the agent of Chagas' disease. Antimicrob Agents Chemother. 2010 Aug; 54(8):3326-34. Engel JC, Ang KK, Chen S, Arkin MR, McKerrow JH, Doyle PS. PMID: 20547819.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    83. Voreloxin is an anticancer quinolone derivative that intercalates DNA and poisons topoisomerase II. PLoS One. 2010 Apr 15; 5(4):e10186. Hawtin RE, Stockett DE, Byl JA, McDowell RS, Nguyen T, Arkin MR, Conroy A, Yang W, Osheroff N, Fox JA. PMID: 20419121.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansCells
    84. Identification and optimization of inhibitors of Trypanosomal cysteine proteases: cruzain, rhodesain, and TbCatB. J Med Chem. 2010 Jan 14; 53(1):52-60. Mott BT, Ferreira RS, Simeonov A, Jadhav A, Ang KK, Leister W, Shen M, Silveira JT, Doyle PS, Arkin MR, McKerrow JH, Inglese J, Austin CP, Thomas CJ, Shoichet BK, Maloney DJ. PMID: 19908842.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    85. Novel non-peptidic vinylsulfones targeting the S2 and S3 subsites of parasite cysteine proteases. Bioorg Med Chem Lett. 2009 Nov 01; 19(21):6218-21. Bryant C, Kerr ID, Debnath M, Ang KK, Ratnam J, Ferreira RS, Jaishankar P, Zhao D, Arkin MR, McKerrow JH, Brinen LS, Renslo AR. PMID: 19773167.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    86. Two approaches to discovering and developing new drugs for Chagas disease. Mem Inst Oswaldo Cruz. 2009 Jul; 104 Suppl 1:263-9. McKerrow JH, Doyle PS, Engel JC, Podust LM, Robertson SA, Ferreira R, Saxton T, Arkin M, Kerr ID, Brinen LS, Craik CS. PMID: 19753483.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimals
    87. The road less traveled: modulating signal transduction enzymes by inhibiting their protein-protein interactions. Curr Opin Chem Biol. 2009 Jun; 13(3):284-90. Arkin MR, Whitty A. PMID: 19553156.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansAnimalsCells
    88. The marine sponge Diacarnus bismarckensis as a source of peroxiterpene inhibitors of Trypanosoma brucei, the causative agent of sleeping sickness. J Nat Prod. 2009 Feb 27; 72(2):218-22. Rubio BK, Tenney K, Ang KH, Abdulla M, Arkin M, McKerrow JH, Crews P. PMID: 19159277.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    89. SNS-032 is a potent and selective CDK 2, 7 and 9 inhibitor that drives target modulation in patient samples. Cancer Chemother Pharmacol. 2009 Sep; 64(4):723-32. Conroy A, Stockett DE, Walker D, Arkin MR, Hoch U, Fox JA, Hawtin RE. PMID: 19169685.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCellsCTClinical Trials
    90. HER-2-directed, small-molecule antagonists. Curr Opin Investig Drugs. 2008 Dec; 9(12):1264-76. Arkin M, Moasser MM. PMID: 19037833.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    91. A diaminocyclohexyl analog of SNS-032 with improved permeability and bioavailability properties. Bioorg Med Chem Lett. 2008 Nov 01; 18(21):5763-5. Choong IC, Serafimova I, Fan J, Stockett D, Chan E, Cheeti S, Lu Y, Fahr B, Pham P, Arkin MR, Walker DH, Hoch U. PMID: 18842409.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    92. Identification of Nonpeptidic Small-Molecule Inhibitors of Interleukin-2. ChemInform. 2005 Jul 5; 36(27). Nathan D. Waal, Wenjin Yang, Johan D. Oslob, Michelle R. Arkin, Jennifer Hyde, Wanli Lu, Robert S. McDowell, Chul H. Yu, Brian C. Raimundo. .
      View in: Publisher Site   Mentions:
    93. Protein-protein interactions and cancer: small molecules going in for the kill. Curr Opin Chem Biol. 2005 Jun; 9(3):317-24. Arkin M. PMID: 15939335.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    94. Identification of nonpeptidic small-molecule inhibitors of interleukin-2. Bioorg Med Chem Lett. 2005 Feb 15; 15(4):983-7. Waal ND, Yang W, Oslob JD, Arkin MR, Hyde J, Lu W, McDowell RS, Yu CH, Raimundo BC. PMID: 15686897.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    95. Integrating fragment assembly and biophysical methods in the chemical advancement of small-molecule antagonists of IL-2: an approach for inhibiting protein-protein interactions. J Med Chem. 2004 Jun 03; 47(12):3111-30. Raimundo BC, Oslob JD, Braisted AC, Hyde J, McDowell RS, Randal M, Waal ND, Wilkinson J, Yu CH, Arkin MR. PMID: 15163192.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    96. Small-molecule inhibitors of protein-protein interactions: progressing towards the dream. Nat Rev Drug Discov. 2004 Apr; 3(4):301-17. Arkin MR, Wells JA. PMID: 15060526.
      View in: PubMed   Mentions: 414     Fields:    Translation:HumansAnimalsCells
    97. Discovery and characterization of cooperative ligand binding in the adaptive region of interleukin-2. Biochemistry. 2003 Jun 03; 42(21):6475-83. Hyde J, Braisted AC, Randal M, Arkin MR. PMID: 12767230.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    98. Discovery of a potent small molecule IL-2 inhibitor through fragment assembly. J Am Chem Soc. 2003 Apr 02; 125(13):3714-5. Braisted AC, Oslob JD, Delano WL, Hyde J, McDowell RS, Waal N, Yu C, Arkin MR, Raimundo BC. PMID: 12656598.
      View in: PubMed   Mentions: 31     Fields:    Translation:Cells
    99. Binding of small molecules to an adaptive protein-protein interface. Proc Natl Acad Sci U S A. 2003 Feb 18; 100(4):1603-8. Arkin MR, Randal M, DeLano WL, Hyde J, Luong TN, Oslob JD, Raphael DR, Taylor L, Wang J, McDowell RS, Wells JA, Braisted AC. PMID: 12582206.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansCells
    100. Drug discovery at signaling interfaces. Ernst Schering Res Found Workshop. 2003; (42):19-27. Wells J, Arkin M, Braisted A, DeLano W, McDowell B, Oslob J, Raimundo B, Randal M. PMID: 12664533.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    101. Drug Discovery at Signaling Interfaces. Small Molecule — Protein Interactions. 2003 Jan 1; 19-27. J. Wells, M. Arkin, A. Braisted, W. DeLano, B. McDowell, J. Oslob, B. Raimundo, M. Randal. .
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    102. A new data analysis method to determine binding constants of small molecules to proteins using equilibrium analytical ultracentrifugation with absorption optics. Anal Biochem. 2001 Dec 01; 299(1):98-107. Arkin M, Lear JD. PMID: 11726190.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    103. In Vitro Mutagenesis. Brenner\u0027s Encyclopedia of Genetics. 2001 Jan 1; (Proceedings of the National Academy of Sciences of the United States of America901993):46-50. M. Arkin. .
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    104. In vitro Mutagenesis. Encyclopedia of Genetics. 2001 Jan 1; (Proceedings of the National Academy of Sciences, USA901993):1010-1014. M. Arkin. .
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    105. Mutational Analysis. Encyclopedia of Genetics. 2001 Jan 1; (Biochemistry351996):1279-1284. M. Arkin. .
      View in: Publisher Site   Mentions:
    106. Probing the importance of second sphere residues in an esterolytic antibody by phage display. J Mol Biol. 1998 Dec 11; 284(4):1083-94. Arkin MR, Wells JA. PMID: 9837728.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    107. Long-range oxidation of guanine by Ru(III) in duplex DNA. Chem Biol. 1997 May; 4(5):389-400. Arkin MR, Stemp ED, Pulver SC, Barton JK. PMID: 9195873.
      View in: PubMed   Mentions: 22     Fields:    Translation:Cells
    108. Rates of DNA-mediated electron transfer between metallointercalators. Science. 1996 Jul 26; 273(5274):475-80. Arkin MR, Stemp ED, Holmlin RE, Barton JK, Hörmann A, Olson EJ, Barbara PF. PMID: 8662532.
      View in: PubMed   Mentions: 20     Fields:    Translation:Cells
    109. Fast photoinduced electron transfer through DNA intercalation. Proc Natl Acad Sci U S A. 1994 Jun 07; 91(12):5315-9. Murphy CJ, Arkin MR, Ghatlia ND, Bossmann S, Turro NJ, Barton JK. PMID: 8202486.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    110. Long-range photoinduced electron transfer through a DNA helix. Science. 1993 Nov 12; 262(5136):1025-9. Murphy CJ, Arkin MR, Jenkins Y, Ghatlia ND, Bossmann SH, Turro NJ, Barton JK. PMID: 7802858.
      View in: PubMed   Mentions: 64     Fields:    Translation:Cells
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