Cassandre Labelle-Dumais, PhD

Title(s)Associate Researcher, Ophthalmology
SchoolSchool of Medicine
Address555 Mission Bay Blvd South, #284
San Francisco CA 94158
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Impaired intracellular Ca2+ signaling contributes to age-related cerebral small vessel disease in Col4a1 mutant mice. Sci Signal. 2023 11 14; 16(811):eadi3966. Yamasaki E, Thakore P, Ali S, Sanchez Solano A, Wang X, Gao X, Labelle-Dumais C, Chaumeil MM, Gould DB, Earley S. PMID: 37963192; PMCID: PMC10726848.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    2. PI3K block restores age-dependent neurovascular coupling defects associated with cerebral small vessel disease. Proc Natl Acad Sci U S A. 2023 08 29; 120(35):e2306479120. Thakore P, Yamasaki E, Ali S, Sanchez Solano A, Labelle-Dumais C, Gao X, Chaumeil MM, Gould DB, Earley S. PMID: 37607233; PMCID: PMC10467353.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    3. PI3K block restores age-dependent neurovascular coupling defects associated with cerebral small vessel disease. bioRxiv. 2023 Mar 06. Thakore P, Yamasaki E, Ali S, Solano AS, Labelle-Dumais C, Gao X, Chaumeil MM, Gould DB, Earley S. PMID: 36945616; PMCID: PMC10028793.
      View in: PubMed   Mentions:
    4. Faulty TRPM4 channels underlie age-dependent cerebral vascular dysfunction in Gould syndrome. Proc Natl Acad Sci U S A. 2023 01 31; 120(5):e2217327120. Yamasaki E, Ali S, Sanchez Solano A, Thakore P, Smith M, Wang X, Labelle-Dumais C, Gould DB, Earley S. PMID: 36693102; PMCID: PMC9945977.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    5. Elevated TGFβ signaling contributes to cerebral small vessel disease in mouse models of Gould syndrome. Matrix Biol. 2023 01; 115:48-70. Branyan K, Labelle-Dumais C, Wang X, Hayashi G, Lee B, Peltz Z, Gorman S, Li BQ, Mao M, Gould DB. PMID: 36435425; PMCID: PMC10393528.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    6. Elevated TGFβ signaling contributes to ocular anterior segment dysgenesis in Col4a1 mutant mice. Matrix Biol. 2022 06; 110:151-173. Mao M, Labelle-Dumais C, Tufa SF, Keene DR, Gould DB. PMID: 35525525; PMCID: PMC10410753.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    7. Identification of MFRP and the secreted serine proteases PRSS56 and ADAMTS19 as part of a molecular network involved in ocular growth regulation. PLoS Genet. 2021 03; 17(3):e1009458. Koli S, Labelle-Dumais C, Zhao Y, Paylakhi S, Nair KS. PMID: 33755662; PMCID: PMC8018652.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    8. Loss of PRSS56 function leads to ocular angle defects and increased susceptibility to high intraocular pressure. Dis Model Mech. 2020 05 29; 13(5). Labelle-Dumais C, Pyatla G, Paylakhi S, Tolman NG, Hameed S, Seymens Y, Dang E, Mandal AK, Senthil S, Khanna RC, Kabra M, Kaur I, John SWM, Chakrabarti S, Nair KS. PMID: 32152063; PMCID: PMC7272341.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    9. COL4A1 Mutations Cause Neuromuscular Disease with Tissue-Specific Mechanistic Heterogeneity. Am J Hum Genet. 2019 05 02; 104(5):847-860. Labelle-Dumais C, Schuitema V, Hayashi G, Hoff K, Gong W, Dao DQ, Ullian EM, Oishi P, Margeta M, Gould DB. PMID: 31051113; PMCID: PMC6506795.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimals
    10. Use of sodium 4-phenylbutyrate to define therapeutic parameters for reducing intracerebral hemorrhage and myopathy in Col4a1 mutant mice. Dis Model Mech. 2018 07 04; 11(7). Hayashi G, Labelle-Dumais C, Gould DB. PMID: 29895609; PMCID: PMC6078406.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    11. Müller glia-derived PRSS56 is required to sustain ocular axial growth and prevent refractive error. PLoS Genet. 2018 03; 14(3):e1007244. Paylakhi S, Labelle-Dumais C, Tolman NG, Sellarole MA, Seymens Y, Saunders J, Lakosha H, deVries WN, Orr AC, Topilko P, John SW, Nair KS. PMID: 29529029; PMCID: PMC5864079.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    12. Type IV Collagens and Basement Membrane Diseases: Cell Biology and Pathogenic Mechanisms. Curr Top Membr. 2015; 76:61-116. Mao M, Alavi MV, Labelle-Dumais C, Gould DB. PMID: 26610912.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimals
    13. Allelic heterogeneity contributes to variability in ocular dysgenesis, myopathy and brain malformations caused by Col4a1 and Col4a2 mutations. Hum Mol Genet. 2014 Apr 01; 23(7):1709-22. Kuo DS, Labelle-Dumais C, Mao M, Jeanne M, Kauffman WB, Allen J, Favor J, Gould DB. PMID: 24203695; PMCID: PMC3943517.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    14. COL4A1 and COL4A2 mutations and disease: insights into pathogenic mechanisms and potential therapeutic targets. Hum Mol Genet. 2012 Oct 15; 21(R1):R97-110. Kuo DS, Labelle-Dumais C, Gould DB. PMID: 22914737; PMCID: PMC3459649.
      View in: PubMed   Mentions: 134     Fields:    Translation:HumansAnimalsCells
    15. COL4A1 mutations in patients with sporadic late-onset intracerebral hemorrhage. Ann Neurol. 2012 Apr; 71(4):470-7. Weng YC, Sonni A, Labelle-Dumais C, de Leau M, Kauffman WB, Jeanne M, Biffi A, Greenberg SM, Rosand J, Gould DB. PMID: 22522439; PMCID: PMC3335762.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    16. COL4A2 mutations impair COL4A1 and COL4A2 secretion and cause hemorrhagic stroke. Am J Hum Genet. 2012 Jan 13; 90(1):91-101. Jeanne M, Labelle-Dumais C, Jorgensen J, Kauffman WB, Mancini GM, Favor J, Valant V, Greenberg SM, Rosand J, Gould DB. PMID: 22209247; PMCID: PMC3257894.
      View in: PubMed   Mentions: 93     Fields:    Translation:HumansAnimalsCells
    17. COL4A1 mutations cause ocular dysgenesis, neuronal localization defects, and myopathy in mice and Walker-Warburg syndrome in humans. PLoS Genet. 2011 May; 7(5):e1002062. Labelle-Dumais C, Dilworth DJ, Harrington EP, de Leau M, Lyons D, Kabaeva Z, Manzini MC, Dobyns WB, Walsh CA, Michele DE, Gould DB. PMID: 21625620; PMCID: PMC3098190.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimalsCells
    18. Manitoba-oculo-tricho-anal (MOTA) syndrome is caused by mutations in FREM1. J Med Genet. 2011 Jun; 48(6):375-82. Slavotinek AM, Baranzini SE, Schanze D, Labelle-Dumais C, Short KM, Chao R, Yahyavi M, Bijlsma EK, Chu C, Musone S, Wheatley A, Kwok PY, Marles S, Fryns JP, Maga AM, Hassan MG, Gould DB, Madireddy L, Li C, Cox TC, Smyth I, Chudley AE, Zenker M. PMID: 21507892; PMCID: PMC4294942.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    19. Peri-pubertal emergence of UNC-5 homologue expression by dopamine neurons in rodents. PLoS One. 2010 Jul 08; 5(7):e11463. Manitt C, Labelle-Dumais C, Eng C, Grant A, Mimee A, Stroh T, Flores C. PMID: 20628609; PMCID: PMC2900213.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    20. Post-pubertal emergence of a dopamine phenotype in netrin-1 receptor-deficient mice. Eur J Neurosci. 2009 Oct; 30(7):1318-28. Grant A, Speed Z, Labelle-Dumais C, Flores C. PMID: 19788579.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    21. Altered netrin-1 receptor expression in dopamine terminal regions following neonatal ventral hippocampal lesions in the rat. Synapse. 2009 Jan; 63(1):54-60. Flores C, Bhardwaj SK, Labelle-Dumais C, Srivastava LK. PMID: 18932228.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    22. Chronic phencyclidine treatment increases dendritic spine density in prefrontal cortex and nucleus accumbens neurons. Synapse. 2007 Dec; 61(12):978-84. Flores C, Wen X, Labelle-Dumais C, Kolb B. PMID: 17879264.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    23. Netrin-1 receptor-deficient mice show enhanced mesocortical dopamine transmission and blunted behavioural responses to amphetamine. Eur J Neurosci. 2007 Dec; 26(11):3215-28. Grant A, Hoops D, Labelle-Dumais C, Prévost M, Rajabi H, Kolb B, Stewart J, Arvanitogiannis A, Flores C. PMID: 18005074.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    24. Regulation of netrin-1 receptors by amphetamine in the adult brain. Neuroscience. 2007 Dec 19; 150(4):764-73. Yetnikoff L, Labelle-Dumais C, Flores C. PMID: 17996376; PMCID: PMC4880477.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    25. Impaired progesterone production in Nr5a2+/- mice leads to a reduction in female reproductive function. Biol Reprod. 2007 Aug; 77(2):217-25. Labelle-Dumais C, Paré JF, Bélanger L, Farookhi R, Dufort D. PMID: 17409375.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    26. Nuclear receptor NR5A2 is required for proper primitive streak morphogenesis. Dev Dyn. 2006 Dec; 235(12):3359-69. Labelle-Dumais C, Jacob-Wagner M, Paré JF, Bélanger L, Dufort D. PMID: 17075876.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    27. Uterine Wnt/beta-catenin signaling is required for implantation. Proc Natl Acad Sci U S A. 2005 Jun 14; 102(24):8579-84. Mohamed OA, Jonnaert M, Labelle-Dumais C, Kuroda K, Clarke HJ, Dufort D. PMID: 15930138; PMCID: PMC1150820.
      View in: PubMed   Mentions: 89     Fields:    Translation:AnimalsCells
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