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Sergio Baranzini, PhD

Title(s)Professor, Neurology
SchoolSchool of Medicine
Address675 Nelson Rising Lane
San Francisco CA 94158
Phone415-502-6865
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    Other Positions
    Title(s)UCSF Weill Institute for Neurosciences


    Collapse Biography 
    Collapse Education and Training
    University of Buenos Aires, ArgentinaBS/MS1992Biochemistry/Biotechnology
    University of Buenos Aires, ArgentinaPhD1997Biochemistry
    University of California, San FranciscoPostdoctoral Fellow2001Neurogenetics
    Collapse Awards and Honors
    University of Buenos Aires, Argentina1992Undergraduate scholarship for research in Molecular Biology
    University of Buenos Aires, Argentina1993Graduate Fellowship for research in Molecular Biology
    University of Buenos Aires, Argentina1995Graduate Fellowship for research in Medical Genetics
    Argentine Society of Genetics1996Best Presentation Award. XXVII Genetics Annual Meeting
    National Academy of Medicine, Argentina1996Adolfo Noceti and Atilio Tiscornia Award for ophthalmology research
    University of Buenos Aires1996Advanced Graduate Fellowship for research in Molecular Biology
    University of Buenos Aires1997Advanced Graduate Fellowship for research in Molecular Biology
    National Multiple Sclerosis Society (US)2001Advanced Postdoctoral Fellowship
    National Multiple Sclerosis Society (US)2009  - 2014Harry Weaver Neuroscience Scholar Award
    Department of Neurology. UCSF2010Endowed Chair in Neurology
    National Multiple Sclerosis Society (US)2015Stephen C. Reingold award

    Collapse Overview 
    Collapse Overview
    Sergio E. Baranzini earned his degree in clinical biochemistry from the University of Buenos Aires, Argentina, in 1992. He graduated from the same institution in 1997 obtaining a PhD with honors in human molecular genetics. The subject of his PhD thesis was the characterization of genetic mutations leading to Duchenne’s muscular dystrophy. Dr. Baranzini then moved to the University of California at San Francisco to specialize in the analysis of complex hereditary diseases, in particular multiple sclerosis. During his postdoctoral stay in UCSF Dr. Baranzini employed state-of-the art methods to explore MS pathogenesis, including immunology, molecular biology, genomics and bioinformatics. Since 2003 Dr. Baranzini is faculty in the Department of Neurology at UCSF, where he currently holds the title of Associate Professor In-Residence. His research involves the large throughout analysis of samples from MS patients to characterize the activity of genes during: i) different stages of the disease (i.e. remission vs. relapse), ii) differential response to treatment (i.e. good responders vs. poor responders), and iii) disease progression (i.e. benign vs. severe). In addition Dr. Baranzini is collaborating with several interdisciplinary teams worldwide to integrate all the available knowledge obtained in different research domains in an approach known as systems biology. Dr Baranzini’s current research involves immunological studies using the EAE model, sequencing of whole genomes and transcriptomes from patients with multiple sclerosis and developing bioinformatics tools to integrate this information with that coming from other high throughput technologies. Dr Baranzini uses a combination of “wet lab” methods including DNA microarrays, proteomics, and laser capture microdissection, in combination with “dry lab” analytical approaches encompassing bioinformatics, complexity theory, and mathematical modeling.
    Dr. Baranzini has published his research on MS in several top-tier journals like Science, Nature, PNAS, J Immunol, and PLos Biol. He is a member of the American Association of Immunologists, and an elected member of the American Neurological Association. He also serves as an ad-hoc reviewer for many specialized journals.

    Collapse Research 
    Collapse Research Activities and Funding
    EVIDARA: Automated Evidential Support from Raw Data for relay agents in Biomedical KG Queries
    NIH OT2TR003450Jan 24, 2020 - Jan 23, 2022
    Role: Co-Principal Investigator
    The genetic basis of progression in multiple sclerosis
    NIH R01NS099240Sep 30, 2017 - Dec 31, 2021
    Role: Principal Investigator
    Post GWAS approach to identify cell-specific genetic pathways underlying MS risk
    NIH R01NS088155Sep 15, 2014 - Jul 31, 2019
    Role: Principal Investigator
    EXTENSIVE SEARCH FOR AN X-LINKED ACC GENE
    NIH F05NS010448Mar 1, 1998
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Websites
    Collapse In The News
    Collapse Academic Senate

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Knowledge Network Embedding of Transcriptomic Data from Spaceflown Mice Uncovers Signs and Symptoms Associated with Terrestrial Diseases. Life (Basel). 2021 Jan 12; 11(1). Nelson CA, Acuna AU, Paul AM, Scott RT, Butte AJ, Cekanaviciute E, Baranzini SE, Costes SV. PMID: 33445483.
      View in: PubMed   Mentions:
    2. Cell type-specific transcriptomics identifies neddylation as a novel therapeutic target in multiple sclerosis. Brain. 2020 Dec 29. Kim K, Pröbstel AK, Baumann R, Dyckow J, Landefeld J, Kogl E, Madireddy L, Loudermilk R, Eggers EL, Singh S, Caillier SJ, Hauser SL, Cree BAC. PMID: 33374005.
      View in: PubMed   Mentions:    Fields:    
    3. Gut microbiota-specific IgA+ B cells traffic to the CNS in active multiple sclerosis. Sci Immunol. 2020 11 20; 5(53). Pröbstel AK, Zhou X, Baumann R, Wischnewski S, Kutza M, Rojas OL, Sellrie K, Bischof A, Kim K, Ramesh A, Dandekar R, Greenfield AL, Schubert RD, Bisanz JE, Vistnes S, Khaleghi K, Landefeld J, Kirkish G, Liesche-Starnecker F, Ramaglia V, Singh S, Tran EB, Barba P, Zorn K, Oechtering J, Forsberg K, Shiow LR, Henry RG, Graves J, Cree BAC, Hauser SL, Kuhle J, Gelfand JM, Andersen PM, Schlegel J, Turnbaugh PJ, Seeberger PH, Gommerman JL, Wilson MR, Schirmer L, Baranzini SE. PMID: 33219152.
      View in: PubMed   Mentions:    Fields:    
    4. Mendelian randomization study shows no causal effects of serum urate levels on the risk of MS. Neurol Neuroimmunol Neuroinflamm. 2021 Jan; 8(1). Harroud A, Richards JB, Baranzini SE. PMID: 33214142.
      View in: PubMed   Mentions:    Fields:    
    5. Levels of brain-derived neurotrophic factor in patients with multiple sclerosis. Ann Clin Transl Neurol. 2020 11; 7(11):2251-2261. Naegelin Y, Saeuberli K, Schaedelin S, Dingsdale H, Magon S, Baranzini S, Amann M, Parmar K, Tsagkas C, Calabrese P, Penner IK, Kappos L, Barde YA. PMID: 33031634.
      View in: PubMed   Mentions:    Fields:    
    6. A pathogenic and clonally expanded B cell transcriptome in active multiple sclerosis. Proc Natl Acad Sci U S A. 2020 09 15; 117(37):22932-22943. Ramesh A, Schubert RD, Greenfield AL, Dandekar R, Loudermilk R, Sabatino JJ, Koelzer MT, Tran EB, Koshal K, Kim K, Pröbstel AK, Banerji D, Guo CY, Green AJ, Bove RM, DeRisi JL, Gelfand JM, Cree BAC, Zamvil SS, Baranzini SE, Hauser SL, Wilson MR. PMID: 32859762.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    7. SARS-CoV-2 meta-interactome suggests disease-specific, autoimmune pathophysiologies and therapeutic targets. F1000Res. 2020; 9:992. Bellucci G, Ballerini C, Mechelli R, Bigi R, Rinaldi V, Reniè R, Buscarinu MC, Baranzini SE, Madireddy L, Matarese G, Salvetti M, Ristori G. PMID: 33456761.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Vitamin D Regulates MerTK-Dependent Phagocytosis in Human Myeloid Cells. J Immunol. 2020 Jul 15; 205(2):398-406. Clarke J, Yaqubi M, Futhey NC, Sedaghat S, Baufeld C, Blain M, Baranzini S, Butovsky O, Antel J, White JH, Healy LM. PMID: 32540991.
      View in: PubMed   Mentions:    Fields:    
    9. Serum antibodies to phosphatidylcholine in MS. Neurol Neuroimmunol Neuroinflamm. 2020 07; 7(4). Sádaba MC, Rothhammer V, Muñoz Ú, Sebal C, Escudero E, Kivisäkk P, Garcia Sanchez MI, Izquierdo G, Hauser SL, Baranzini SE, Oksenberg JR, Álvarez-Lafuente R, Bakshi R, Weiner HL, Quintana FJ. PMID: 32518205.
      View in: PubMed   Mentions:    Fields:    
    10. microRNA and exosome profiling in multiple sclerosis. Mult Scler. 2020 04; 26(5):599-604. Mycko MP, Baranzini SE. PMID: 31965891.
      View in: PubMed   Mentions:    Fields:    
    11. Early complement genes are associated with visual system degeneration in multiple sclerosis. Brain. 2019 09 01; 142(9):2722-2736. Fitzgerald KC, Kim K, Smith MD, Aston SA, Fioravante N, Rothman AM, Krieger S, Cofield SS, Kimbrough DJ, Bhargava P, Saidha S, Whartenby KA, Green AJ, Mowry EM, Cutter GR, Lublin FD, Baranzini SE, De Jager PL, Calabresi PA. PMID: 31289819.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    12. Genetic variation across RNA metabolism and cell death gene networks is implicated in the semantic variant of primary progressive aphasia. Sci Rep. 2019 07 26; 9(1):10854. Bonham LW, Steele NZR, Karch CM, Broce I, Geier EG, Wen NL, Momeni P, Hardy J, Miller ZA, Gorno-Tempini ML, Hess CP, Lewis P, Miller BL, Seeley WW, Manzoni C, Desikan RS, Baranzini SE, Ferrari R, Yokoyama JS. PMID: 31350420.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    13. Integrating biomedical research and electronic health records to create knowledge-based biologically meaningful machine-readable embeddings. Nat Commun. 2019 07 10; 10(1):3045. Nelson CA, Butte AJ, Baranzini SE. PMID: 31292438.
      View in: PubMed   Mentions: 6     Fields:    
    14. Aberrant oligodendroglial-vascular interactions disrupt the blood-brain barrier, triggering CNS inflammation. Nat Neurosci. 2019 05; 22(5):709-718. Niu J, Tsai HH, Hoi KK, Huang N, Yu G, Kim K, Baranzini SE, Xiao L, Chan JR, Fancy SPJ. PMID: 30988524.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    15. Recirculating Intestinal IgA-Producing Cells Regulate Neuroinflammation via IL-10. Cell. 2019 Apr 04; 177(2):492-493. Rojas OL, Pröbstel AK, Porfilio EA, Wang AA, Charabati M, Sun T, Lee DSW, Galicia G, Ramaglia V, Ward LA, Leung LYT, Najafi G, Khaleghi K, Garcillán B, Li A, Besla R, Naouar I, Cao EY, Chiaranunt P, Burrows K, Robinson HG, Allanach JR, Yam J, Luck H, Campbell DJ, Allman D, Brooks DG, Tomura M, Baumann R, Zamvil SS, Bar-Or A, Horwitz MS, Winer DA, Mortha A, Mackay F, Prat A, Osborne LC, Robbins C, Baranzini SE, Gommerman JL. PMID: 30951673.
      View in: PubMed   Mentions: 6     Fields:    
    16. Silent progression in disease activity-free relapsing multiple sclerosis. Ann Neurol. 2019 05; 85(5):653-666. Cree BAC, Hollenbach JA, Bove R, Kirkish G, Sacco S, Caverzasi E, Bischof A, Gundel T, Zhu AH, Papinutto N, Stern WA, Bevan C, Romeo A, Goodin DS, Gelfand JM, Graves J, Green AJ, Wilson MR, Zamvil SS, Zhao C, Gomez R, Ragan NR, Rush GQ, Barba P, Santaniello A, Baranzini SE, Oksenberg JR, Henry RG, Hauser SL. PMID: 30851128.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    17. Insights into microbiome research 6: The role of consortia in studying the role of microbes in health and disease. Mult Scler. 2019 03; 25(3):336-337. Baranzini SE. PMID: 30801223.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    18. Insights into microbiome research 5: Mapping is first but function must come next. Mult Scler. 2019 02; 25(2):193-195. Baranzini SE. PMID: 30799701.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    19. Selective Estrogen Receptor Modulators Enhance CNS Remyelination Independent of Estrogen Receptors. J Neurosci. 2019 03 20; 39(12):2184-2194. Rankin KA, Mei F, Kim K, Shen YA, Mayoral SR, Desponts C, Lorrain DS, Green AJ, Baranzini SE, Chan JR, Bove R. PMID: 30696729.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    20. Recirculating Intestinal IgA-Producing Cells Regulate Neuroinflammation via IL-10. Cell. 2019 01 24; 176(3):610-624.e18. Rojas OL, Pröbstel AK, Porfilio EA, Wang AA, Charabati M, Sun T, Lee DSW, Galicia G, Ramaglia V, Ward LA, Leung LYT, Najafi G, Khaleghi K, Garcillán B, Li A, Besla R, Naouar I, Cao EY, Chiaranunt P, Burrows K, Robinson HG, Allanach JR, Yam J, Luck H, Campbell DJ, Allman D, Brooks DG, Tomura M, Baumann R, Zamvil SS, Bar-Or A, Horwitz MS, Winer DA, Mortha A, Mackay F, Prat A, Osborne LC, Robbins C, Baranzini SE, Gommerman JL. PMID: 30612739.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    21. Insights into microbiome research 4: The computational analysis. Mult Scler. 2019 01; 25(1):21-22. Baranzini SE. PMID: 30799699.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    22. Multiple Sclerosis-Associated Changes in the Composition and Immune Functions of Spore-Forming Bacteria. mSystems. 2018 Nov-Dec; 3(6). Cekanaviciute E, Pröbstel AK, Thomann A, Runia TF, Casaccia P, Katz Sand I, Crabtree E, Singh S, Morrissey J, Barba P, Gomez R, Knight R, Mazmanian S, Graves J, Cree BAC, Zamvil SS, Baranzini SE. PMID: 30417113.
      View in: PubMed   Mentions:
    23. Disease-modifying therapies alter gut microbial composition in MS. Neurol Neuroimmunol Neuroinflamm. 2019 01; 6(1):e517. Katz Sand I, Zhu Y, Ntranos A, Clemente JC, Cekanaviciute E, Brandstadter R, Crabtree-Hartman E, Singh S, Bencosme Y, Debelius J, Knight R, Cree BAC, Baranzini SE, Casaccia P. PMID: 30568995.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    24. Insights into microbiome research 2: Experimental design, sample collection, and shipment. Mult Scler. 2018 10; 24(11):1419-1420. Baranzini SE. PMID: 30289379.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    25. Protein network analysis reveals selectively vulnerable regions and biological processes in FTD. Neurol Genet. 2018 Oct; 4(5):e266. Bonham LW, Steele NZR, Karch CM, Manzoni C, Geier EG, Wen N, Ofori-Kuragu A, Momeni P, Hardy J, Miller ZA, Hess CP, Lewis P, Miller BL, Seeley WW, Baranzini SE, Desikan RS, Ferrari R, Yokoyama JS. PMID: 30283816.
      View in: PubMed   Mentions:
    26. Insights into microbiome research 3: Who's there versus what are they doing? Mult Scler. 2018 10; 24(12):1541-1542. Baranzini SE. PMID: 30332350.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    27. Insights into microbiome research 1: How to choose appropriate controls for a microbiome study in MS? Mult Scler. 2018 09; 24(10):1278-1279. Baranzini SE. PMID: 30129894.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    28. Genome sequencing uncovers phenocopies in primary progressive multiple sclerosis. Ann Neurol. 2018 07; 84(1):51-63. Jia X, Madireddy L, Caillier S, Santaniello A, Esposito F, Comi G, Stuve O, Zhou Y, Taylor B, Kilpatrick T, Martinelli-Boneschi F, Cree BAC, Oksenberg JR, Hauser SL, Baranzini SE. PMID: 29908077.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    29. Mononuclear cell transcriptome changes associated with dimethyl fumarate in MS. Neurol Neuroimmunol Neuroinflamm. 2018 Jul; 5(4):e470. Gafson AR, Kim K, Cencioni MT, van Hecke W, Nicholas R, Baranzini SE, Matthews PM. PMID: 30283812.
      View in: PubMed   Mentions: 1     Fields:    
    30. Correction: Peroxisome proliferator-activated receptor (PPAR)a expression in T cells mediates gender differences in development of T cell-mediated autoimmunity. J Exp Med. 2018 06 04; 215(6):1765. Dunn SE, Ousman SS, Sobel RA, Zuniga L, Baranzini SE, Youssef S, Crowell A, Loh J, Oksenberg J, Steinman L. PMID: 29773642.
      View in: PubMed   Mentions:    Fields:    
    31. Multiple sclerosis. Lancet. 2018 04 21; 391(10130):1622-1636. Thompson AJ, Baranzini SE, Geurts J, Hemmer B, Ciccarelli O. PMID: 29576504.
      View in: PubMed   Mentions: 124     Fields:    Translation:HumansCells
    32. The microbiome and MS: The influence of the microbiota on MS risk and progression-Session chair summary. Mult Scler. 2018 04; 24(5):587-589. Katz Sand I, Baranzini SE. PMID: 29498302.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    33. Harnessing electronic medical records to advance research on multiple sclerosis. Mult Scler. 2019 03; 25(3):408-418. Damotte V, Lizée A, Tremblay M, Agrawal A, Khankhanian P, Santaniello A, Gomez R, Lincoln R, Tang W, Chen T, Lee N, Villoslada P, Hollenbach JA, Bevan CD, Graves J, Bove R, Goodin DS, Green AJ, Baranzini SE, Cree BA, Henry RG, Hauser SL, Gelfand JM, Gourraud PA. PMID: 29310490.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    34. The Gut Microbiome in Neuromyelitis Optica. Neurotherapeutics. 2018 01; 15(1):92-101. Zamvil SS, Spencer CM, Baranzini SE, Cree BAC. PMID: 29280091.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    35. The Role of the Gut Microbiome in Multiple Sclerosis Risk and Progression: Towards Characterization of the "MS Microbiome". Neurotherapeutics. 2018 01; 15(1):126-134. Pröbstel AK, Baranzini SE. PMID: 29147991.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    36. The era of GWAS is over - Commentary. Mult Scler. 2018 03; 24(3):260-261. Baranzini SE. PMID: 29251183.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    37. The Genetics of Multiple Sclerosis: From 0 to 200 in 50 Years. Trends Genet. 2017 12; 33(12):960-970. Baranzini SE, Oksenberg JR. PMID: 28987266.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    38. Systematic integration of biomedical knowledge prioritizes drugs for repurposing. Elife. 2017 09 22; 6. Himmelstein DS, Lizee A, Hessler C, Brueggeman L, Chen SL, Hadley D, Green A, Khankhanian P, Baranzini SE. PMID: 28936969.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    39. Gut microbiota from multiple sclerosis patients enables spontaneous autoimmune encephalomyelitis in mice. Proc Natl Acad Sci U S A. 2017 10 03; 114(40):10719-10724. Berer K, Gerdes LA, Cekanaviciute E, Jia X, Xiao L, Xia Z, Liu C, Klotz L, Stauffer U, Baranzini SE, Kümpfel T, Hohlfeld R, Krishnamoorthy G, Wekerle H. PMID: 28893994.
      View in: PubMed   Mentions: 119     Fields:    Translation:HumansAnimalsCells
    40. Gut bacteria from multiple sclerosis patients modulate human T cells and exacerbate symptoms in mouse models. Proc Natl Acad Sci U S A. 2017 10 03; 114(40):10713-10718. Cekanaviciute E, Yoo BB, Runia TF, Debelius JW, Singh S, Nelson CA, Kanner R, Bencosme Y, Lee YK, Hauser SL, Crabtree-Hartman E, Sand IK, Gacias M, Zhu Y, Casaccia P, Cree BAC, Knight R, Mazmanian SK, Baranzini SE. PMID: 28893978.
      View in: PubMed   Mentions: 125     Fields:    Translation:HumansAnimalsCells
    41. Data characterizing the ZMIZ1 molecular phenotype of multiple sclerosis. Data Brief. 2017 Apr; 11:364-370. Fewings N, Gatt PN, McKay FC, Parnell GP, Schibeci SD, Edwards J, Basuki MA, Goldinger A, Fabis-Pedrini MJ, Kermode AG, Manrique CP, McCauley JL, Nickles D, Baranzini SE, Burke T, Vucic S, Stewart GJ, Booth DR. PMID: 28275670.
      View in: PubMed   Mentions:
    42. The autoimmune risk gene ZMIZ1 is a vitamin D responsive marker of a molecular phenotype of multiple sclerosis. J Autoimmun. 2017 03; 78:57-69. Fewings NL, Gatt PN, McKay FC, Parnell GP, Schibeci SD, Edwards J, Basuki MA, Goldinger A, Fabis-Pedrini MJ, Kermode AG, Manrique CP, McCauley JL, Nickles D, Baranzini SE, Burke T, Vucic S, Stewart GJ, Booth DR. PMID: 28063629.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    43. Two missense mutations in SALL4 in a patient with microphthalmia, coloboma, and optic nerve hypoplasia. Ophthalmic Genet. 2017 Jul-Aug; 38(4):371-375. Ullah E, Wu D, Madireddy L, Lao R, Ling-Fung Tang P, Wan E, Bardakjian T, Kopinsky S, Kwok PY, Schneider A, Baranzini S, Ansar M, Slavotinek A. PMID: 27661448.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    44. IFN-? orchestrates mesenchymal stem cell plasticity through the signal transducer and activator of transcription 1 and 3 and mammalian target of rapamycin pathways. J Allergy Clin Immunol. 2017 May; 139(5):1667-1676. Vigo T, Procaccini C, Ferrara G, Baranzini S, Oksenberg JR, Matarese G, Diaspro A, Kerlero de Rosbo N, Uccelli A. PMID: 27670240.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    45. Immune cell-specific transcriptional profiling highlights distinct molecular pathways controlled by Tob1 upon experimental autoimmune encephalomyelitis. Sci Rep. 2016 08 22; 6:31603. Didonna A, Cekanaviciute E, Oksenberg JR, Baranzini SE. PMID: 27546286.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    46. Long-term evolution of multiple sclerosis disability in the treatment era. Ann Neurol. 2016 10; 80(4):499-510. Cree BA, Gourraud PA, Oksenberg JR, Bevan C, Crabtree-Hartman E, Gelfand JM, Goodin DS, Graves J, Green AJ, Mowry E, Okuda DT, Pelletier D, von Büdingen HC, Zamvil SS, Agrawal A, Caillier S, Ciocca C, Gomez R, Kanner R, Lincoln R, Lizee A, Qualley P, Santaniello A, Suleiman L, Bucci M, Panara V, Papinutto N, Stern WA, Zhu AH, Cutter GR, Baranzini S, Henry RG, Hauser SL. PMID: 27464262.
      View in: PubMed   Mentions: 54     Fields:    Translation:Humans
    47. Gut microbiome analysis in neuromyelitis optica reveals overabundance of Clostridium perfringens. Ann Neurol. 2016 09; 80(3):443-7. Cree BA, Spencer CM, Varrin-Doyer M, Baranzini SE, Zamvil SS. PMID: 27398819.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    48. Association of HLA Genetic Risk Burden With Disease Phenotypes in Multiple Sclerosis. JAMA Neurol. 2016 07 01; 73(7):795-802. Isobe N, Keshavan A, Gourraud PA, Zhu AH, Datta E, Schlaeger R, Caillier SJ, Santaniello A, Lizée A, Himmelstein DS, Baranzini SE, Hollenbach J, Cree BA, Hauser SL, Oksenberg JR, Henry RG. PMID: 27244296.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    49. Meta-analysis of genome-wide association studies reveals genetic overlap between Hodgkin lymphoma and multiple sclerosis. Int J Epidemiol. 2016 06; 45(3):728-40. Khankhanian P, Cozen W, Himmelstein DS, Madireddy L, Din L, van den Berg A, Matsushita T, Glaser SL, Moré JM, Smedby KE, Baranzini SE, Mack TM, Lizée A, de Sanjosé S, Gourraud PA, Nieters A, Hauser SL, Cocco P, Maynadié M, Foretová L, Staines A, Delahaye-Sourdeix M, Li D, Bhatia S, Melbye M, Onel K, Jarrett R, McKay JD, Oksenberg JR, Hjalgrim H. PMID: 26971321.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    50. A validated gene regulatory network and GWAS identifies early regulators of T cell-associated diseases. Sci Transl Med. 2015 Nov 11; 7(313):313ra178. Gustafsson M, Gawel DR, Alfredsson L, Baranzini S, Björkander J, Blomgran R, Hellberg S, Eklund D, Ernerudh J, Kockum I, Konstantinell A, Lahesmaa R, Lentini A, Liljenström HR, Mattson L, Matussek A, Mellergård J, Mendez M, Olsson T, Pujana MA, Rasool O, Serra-Musach J, Stenmarker M, Tripathi S, Viitala M, Wang H, Zhang H, Nestor CE, Benson M. PMID: 26560356.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    51. Assessing the Power of Exome Chips. PLoS One. 2015; 10(10):e0139642. Page CM, Baranzini SE, Mevik BH, Bos SD, Harbo HF, Andreassen BK. PMID: 26437075.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    52. A non-synonymous single-nucleotide polymorphism associated with multiple sclerosis risk affects the EVI5 interactome. Hum Mol Genet. 2015 Dec 15; 24(24):7151-8. Didonna A, Isobe N, Caillier SJ, Li KH, Burlingame AL, Hauser SL, Baranzini SE, Patsopoulos NA, Oksenberg JR. PMID: 26433934.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    53. Class II HLA interactions modulate genetic risk for multiple sclerosis. Nat Genet. 2015 Oct; 47(10):1107-1113. Moutsianas L, Jostins L, Beecham AH, Dilthey AT, Xifara DK, Ban M, Shah TS, Patsopoulos NA, Alfredsson L, Anderson CA, Attfield KE, Baranzini SE, Barrett J, Binder TMC, Booth D, Buck D, Celius EG, Cotsapas C, D'Alfonso S, Dendrou CA, Donnelly P, Dubois B, Fontaine B, Fugger L, Goris A, Gourraud PA, Graetz C, Hemmer B, Hillert J, Kockum I, Leslie S, Lill CM, Martinelli-Boneschi F, Oksenberg JR, Olsson T, Oturai A, Saarela J, Søndergaard HB, Spurkland A, Taylor B, Winkelmann J, Zipp F, Haines JL, Pericak-Vance MA, Spencer CCA, Stewart G, Hafler DA, Ivinson AJ, Harbo HF, Hauser SL, De Jager PL, Compston A, McCauley JL, Sawcer S, McVean G. PMID: 26343388.
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    132. Predictive modeling of therapy response in multiple sclerosis using gene expression data. Conf Proc IEEE Eng Med Biol Soc. 2006; 2006:5519-22. Mostafavi S, Baranzini S, Oksernberg J, Mousavi P. PMID: 17946311.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    133. Mapping gene activity in complex disorders: Integration of expression and genomic scans for multiple sclerosis. J Neuroimmunol. 2005 Oct; 167(1-2):157-69. Fernald GH, Yeh RF, Hauser SL, Oksenberg JR, Baranzini SE. PMID: 16129498.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    134. Modular transcriptional activity characterizes the initiation and progression of autoimmune encephalomyelitis. J Immunol. 2005 Jun 01; 174(11):7412-22. Baranzini SE, Bernard CC, Oksenberg JR. PMID: 15905590.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    135. Genomics and new targets for multiple sclerosis. Pharmacogenomics. 2005 Mar; 6(2):151-61. Baranzini SE, Oksenberg JR. PMID: 15882133.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    136. Longitudinal analysis of B cell repertoire and antibody gene rearrangements during early HIV infection. Genes Immun. 2005 Feb; 6(1):66-9. Elkins MK, Vittinghoff E, Baranzini SE, Hecht FM, Sriram U, Busch MP, Levy JA, Oksenberg JR. PMID: 15538390.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    137. Transcription-based prediction of response to IFNbeta using supervised computational methods. PLoS Biol. 2005 Jan; 3(1):e2. Baranzini SE, Mousavi P, Rio J, Caillier SJ, Stillman A, Villoslada P, Wyatt MM, Comabella M, Greller LD, Somogyi R, Montalban X, Oksenberg JR. PMID: 15630474.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    138. Gene expression profiling in neurological disorders: toward a systems-level understanding of the brain. Neuromolecular Med. 2004; 6(1):31-51. Baranzini SE. PMID: 15781975.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    139. Mapping multiple sclerosis susceptibility to the HLA-DR locus in African Americans. Am J Hum Genet. 2004 Jan; 74(1):160-7. Oksenberg JR, Barcellos LF, Cree BA, Baranzini SE, Bugawan TL, Khan O, Lincoln RR, Swerdlin A, Mignot E, Lin L, Goodin D, Erlich HA, Schmidt S, Thomson G, Reich DE, Pericak-Vance MA, Haines JL, Hauser SL. PMID: 14669136.
      View in: PubMed   Mentions: 114     Fields:    Translation:Humans
    140. Dynamic regulation of alternative ATP-binding cassette transporter A1 transcripts. Biochem Biophys Res Commun. 2003 Jun 27; 306(2):463-8. Huuskonen J, Abedin M, Vishnu M, Pullinger CR, Baranzini SE, Kane JP, Fielding PE, Fielding CJ. PMID: 12804586.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    141. Osteopontin polymorphisms and disease course in multiple sclerosis. Genes Immun. 2003 Jun; 4(4):312-5. Caillier S, Barcellos LF, Baranzini SE, Swerdlin A, Lincoln RR, Steinman L, Martin E, Haines JL, Pericak-Vance M, Hauser SL, Oksenberg JR. PMID: 12761568.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    142. Direct deletion analysis in two Duchenne muscular dystrophy symptomatic females using polymorphic dinucleotide (CA)n loci within the dystrophin gene. J Biochem Mol Biol. 2003 Mar 31; 36(2):179-84. Giliberto F, Ferreiro V, Dalamón V, Surace E, Cotignola J, Esperante S, Borelina D, Baranzini S, Szijan I. PMID: 12689516.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    143. Pharmacogenomic analysis of interferon receptor polymorphisms in multiple sclerosis. Genes Immun. 2003 Mar; 4(2):147-52. Sriram U, Barcellos LF, Villoslada P, Rio J, Baranzini SE, Caillier S, Stillman A, Hauser SL, Montalban X, Oksenberg JR. PMID: 12618863.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCellsCTClinical Trials
    144. Large-scale gene-expression studies and the challenge of multiple sclerosis. Genome Biol. 2002 Sep 16; 3(10):reviews1027. Baranzini SE, Hauser SL. PMID: 12372148.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    145. The HLA locus and multiple sclerosis in Spain. Role in disease susceptibility, clinical course and response to interferon-beta. J Neuroimmunol. 2002 Sep; 130(1-2):194-201. Villoslada P, Barcellos LF, Rio J, Begovich AB, Tintore M, Sastre-Garriga J, Baranzini SE, Casquero P, Hauser SL, Montalban X, Oksenberg JR. PMID: 12225902.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCellsCTClinical Trials
    146. Gene expression analysis reveals altered brain transcription of glutamate receptors and inflammatory genes in a patient with chronic focal (Rasmussen's) encephalitis. J Neuroimmunol. 2002 Jul; 128(1-2):9-15. Baranzini SE, Laxer K, Bollen A, Oksenberg JR. PMID: 12098505.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    147. Analysis of antibody gene rearrangement, usage, and specificity in chronic focal encephalitis. Neurology. 2002 Mar 12; 58(5):709-16. Baranzini SE, Laxer K, Saketkhoo R, Elkins MK, Parent JM, Mantegazza R, Oksenberg JR. PMID: 11889232.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    148. New insights into the genetics of multiple sclerosis. J Rehabil Res Dev. 2002 Mar-Apr; 39(2):201-9. Baranzini SE, Oksenberg JR, Hauser SL. PMID: 12051464.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    149. The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease. Science. 2001 Nov 23; 294(5547):1731-5. Chabas D, Baranzini SE, Mitchell D, Bernard CC, Rittling SR, Denhardt DT, Sobel RA, Lock C, Karpuj M, Pedotti R, Heller R, Oksenberg JR, Steinman L. PMID: 11721059.
      View in: PubMed   Mentions: 226     Fields:    Translation:HumansAnimalsCells
    150. Multiple sclerosis: genomic rewards. J Neuroimmunol. 2001 Feb 15; 113(2):171-84. Oksenberg JR, Baranzini SE, Barcellos LF, Hauser SL. PMID: 11164900.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    151. Transcriptional analysis of multiple sclerosis brain lesions reveals a complex pattern of cytokine expression. J Immunol. 2000 Dec 01; 165(11):6576-82. Baranzini SE, Elfstrom C, Chang SY, Butunoi C, Murray R, Higuchi R, Oksenberg JR. PMID: 11086101.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    152. B cell repertoire diversity and clonal expansion in multiple sclerosis brain lesions. J Immunol. 1999 Nov 01; 163(9):5133-44. Baranzini SE, Jeong MC, Butunoi C, Murray RS, Bernard CC, Oksenberg JR. PMID: 10528220.
      View in: PubMed   Mentions: 85     Fields:    Translation:HumansCells
    153. Carrier detection in Duchenne and Becker muscular dystrophy Argentine families. Clin Genet. 1998 Dec; 54(6):503-11. Baranzini SE, Giliberto F, Dalamon V, Barreiro C, García-Erro M, Grippo J, Szijan I. PMID: 9894797.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    154. Deletion patterns in Argentine patients with Duchenne and Becker muscular dystrophy. Neurol Res. 1998 Jul; 20(5):409-414. Baranzini SE, Giliberto F, Herrera M, Bernath V, Barreiro C, Garcia Erro M, Grippo J, Szijan I. PMID: 9664586.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    155. Clinical, cytogenetic, and molecular testing of Argentine patients with retinoblastoma. J AAPOS. 1998 Apr; 2(2):102-7. Arbetman A, Abdala M, Fandiño A, Herrera J, Baranzini S, Borelina D, Parma D, Manzitti J, Barreiro C, Giliberto F, Szijan I. PMID: 10530971.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    156. Four new polymorphisms in the human dystrophin gene from an Argentinian population. Muscle Nerve. 1997 Nov; 20(11):1451-3. Baranzini SE, Lenk U, Szijan I, Speer A. PMID: 9342163.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    157. Patient with an Xp21 contiguous gene deletion syndrome in association with agenesis of the corpus callosum. Am J Med Genet. 1997 Jun 13; 70(3):216-21. Baranzini SE, del Rey G, Nigro N, Szijan I, Chamoles N, Cresto JC. PMID: 9188656.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    158. A new point mutation (M313T) in the thyroid hormone receptor beta gene in a patient with resistance to thyroid hormone. Thyroid. 1997 Feb; 7(1):43-4. di Fulvio M, Chiesa AE, Baranzini SE, Gruñiero-Papendieck L, Masini-Repiso AM, Targovnik HM. PMID: 9086569.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
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