Sergio Baranzini, PhD
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Title(s) | Professor, Neurology |
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School | School of Medicine |
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Address | 675 Nelson Rising Lane San Francisco CA 94158
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Phone | 415-502-6865 |
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vCard | Download vCard |
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Title(s) | UCSF Weill Institute for Neurosciences |
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Biography University of Buenos Aires, Argentina | BS/MS | 1992 | Biochemistry/Biotechnology | University of Buenos Aires, Argentina | PhD | 1997 | Biochemistry | University of California, San Francisco | Postdoctoral Fellow | 2001 | Neurogenetics |
University of Buenos Aires, Argentina | 1992 | | Undergraduate scholarship for research in Molecular Biology | University of Buenos Aires, Argentina | 1993 | | Graduate Fellowship for research in Molecular Biology | University of Buenos Aires, Argentina | 1995 | | Graduate Fellowship for research in Medical Genetics | Argentine Society of Genetics | 1996 | | Best Presentation Award. XXVII Genetics Annual Meeting | National Academy of Medicine, Argentina | 1996 | | Adolfo Noceti and Atilio Tiscornia Award for ophthalmology research | University of Buenos Aires | 1996 | | Advanced Graduate Fellowship for research in Molecular Biology | University of Buenos Aires | 1997 | | Advanced Graduate Fellowship for research in Molecular Biology | National Multiple Sclerosis Society (US) | 2001 | | Advanced Postdoctoral Fellowship | National Multiple Sclerosis Society (US) | 2009
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| 2014 | Harry Weaver Neuroscience Scholar Award | Department of Neurology. UCSF | 2010 | | Endowed Chair in Neurology | National Multiple Sclerosis Society (US) | 2015 | | Stephen C. Reingold award |
Overview Sergio E. Baranzini earned his degree in clinical biochemistry from the University of Buenos Aires, Argentina, in 1992. He graduated from the same institution in 1997 obtaining a PhD with honors in human molecular genetics. The subject of his PhD thesis was the characterization of genetic mutations leading to Duchenne’s muscular dystrophy. Dr. Baranzini then moved to the University of California at San Francisco to specialize in the analysis of complex hereditary diseases, in particular multiple sclerosis. During his postdoctoral stay in UCSF Dr. Baranzini employed state-of-the art methods to explore MS pathogenesis, including immunology, molecular biology, genomics and bioinformatics. Since 2003 Dr. Baranzini is faculty in the Department of Neurology at UCSF, where he currently holds the title of Associate Professor In-Residence. His research involves the large throughout analysis of samples from MS patients to characterize the activity of genes during: i) different stages of the disease (i.e. remission vs. relapse), ii) differential response to treatment (i.e. good responders vs. poor responders), and iii) disease progression (i.e. benign vs. severe). In addition Dr. Baranzini is collaborating with several interdisciplinary teams worldwide to integrate all the available knowledge obtained in different research domains in an approach known as systems biology. Dr Baranzini’s current research involves immunological studies using the EAE model, sequencing of whole genomes and transcriptomes from patients with multiple sclerosis and developing bioinformatics tools to integrate this information with that coming from other high throughput technologies. Dr Baranzini uses a combination of “wet lab” methods including DNA microarrays, proteomics, and laser capture microdissection, in combination with “dry lab” analytical approaches encompassing bioinformatics, complexity theory, and mathematical modeling. Dr. Baranzini has published his research on MS in several top-tier journals like Science, Nature, PNAS, J Immunol, and PLos Biol. He is a member of the American Association of Immunologists, and an elected member of the American Neurological Association. He also serves as an ad-hoc reviewer for many specialized journals.
Research ORNG Applications Bibliographic
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Knowledge Network Embedding of Transcriptomic Data from Spaceflown Mice Uncovers Signs and Symptoms Associated with Terrestrial Diseases. Life (Basel). 2021 Jan 12; 11(1).
Nelson CA, Acuna AU, Paul AM, Scott RT, Butte AJ, Cekanaviciute E, Baranzini SE, Costes SV. PMID: 33445483.
View in: PubMed Mentions:
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Cell type-specific transcriptomics identifies neddylation as a novel therapeutic target in multiple sclerosis. Brain. 2020 Dec 29.
Kim K, Pröbstel AK, Baumann R, Dyckow J, Landefeld J, Kogl E, Madireddy L, Loudermilk R, Eggers EL, Singh S, Caillier SJ, Hauser SL, Cree BAC. PMID: 33374005.
View in: PubMed Mentions: Fields:
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Gut microbiota-specific IgA+ B cells traffic to the CNS in active multiple sclerosis. Sci Immunol. 2020 11 20; 5(53).
Pröbstel AK, Zhou X, Baumann R, Wischnewski S, Kutza M, Rojas OL, Sellrie K, Bischof A, Kim K, Ramesh A, Dandekar R, Greenfield AL, Schubert RD, Bisanz JE, Vistnes S, Khaleghi K, Landefeld J, Kirkish G, Liesche-Starnecker F, Ramaglia V, Singh S, Tran EB, Barba P, Zorn K, Oechtering J, Forsberg K, Shiow LR, Henry RG, Graves J, Cree BAC, Hauser SL, Kuhle J, Gelfand JM, Andersen PM, Schlegel J, Turnbaugh PJ, Seeberger PH, Gommerman JL, Wilson MR, Schirmer L, Baranzini SE. PMID: 33219152.
View in: PubMed Mentions: Fields:
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Mendelian randomization study shows no causal effects of serum urate levels on the risk of MS. Neurol Neuroimmunol Neuroinflamm. 2021 Jan; 8(1).
Harroud A, Richards JB, Baranzini SE. PMID: 33214142.
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Levels of brain-derived neurotrophic factor in patients with multiple sclerosis. Ann Clin Transl Neurol. 2020 11; 7(11):2251-2261.
Naegelin Y, Saeuberli K, Schaedelin S, Dingsdale H, Magon S, Baranzini S, Amann M, Parmar K, Tsagkas C, Calabrese P, Penner IK, Kappos L, Barde YA. PMID: 33031634.
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A pathogenic and clonally expanded B cell transcriptome in active multiple sclerosis. Proc Natl Acad Sci U S A. 2020 09 15; 117(37):22932-22943.
Ramesh A, Schubert RD, Greenfield AL, Dandekar R, Loudermilk R, Sabatino JJ, Koelzer MT, Tran EB, Koshal K, Kim K, Pröbstel AK, Banerji D, Guo CY, Green AJ, Bove RM, DeRisi JL, Gelfand JM, Cree BAC, Zamvil SS, Baranzini SE, Hauser SL, Wilson MR. PMID: 32859762.
View in: PubMed Mentions: 3 Fields: Translation: HumansCells
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SARS-CoV-2 meta-interactome suggests disease-specific, autoimmune pathophysiologies and therapeutic targets. F1000Res. 2020; 9:992.
Bellucci G, Ballerini C, Mechelli R, Bigi R, Rinaldi V, Reniè R, Buscarinu MC, Baranzini SE, Madireddy L, Matarese G, Salvetti M, Ristori G. PMID: 33456761.
View in: PubMed Mentions: Fields: Translation: Humans
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Vitamin D Regulates MerTK-Dependent Phagocytosis in Human Myeloid Cells. J Immunol. 2020 Jul 15; 205(2):398-406.
Clarke J, Yaqubi M, Futhey NC, Sedaghat S, Baufeld C, Blain M, Baranzini S, Butovsky O, Antel J, White JH, Healy LM. PMID: 32540991.
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Serum antibodies to phosphatidylcholine in MS. Neurol Neuroimmunol Neuroinflamm. 2020 07; 7(4).
Sádaba MC, Rothhammer V, Muñoz Ú, Sebal C, Escudero E, Kivisäkk P, Garcia Sanchez MI, Izquierdo G, Hauser SL, Baranzini SE, Oksenberg JR, Álvarez-Lafuente R, Bakshi R, Weiner HL, Quintana FJ. PMID: 32518205.
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microRNA and exosome profiling in multiple sclerosis. Mult Scler. 2020 04; 26(5):599-604.
Mycko MP, Baranzini SE. PMID: 31965891.
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Early complement genes are associated with visual system degeneration in multiple sclerosis. Brain. 2019 09 01; 142(9):2722-2736.
Fitzgerald KC, Kim K, Smith MD, Aston SA, Fioravante N, Rothman AM, Krieger S, Cofield SS, Kimbrough DJ, Bhargava P, Saidha S, Whartenby KA, Green AJ, Mowry EM, Cutter GR, Lublin FD, Baranzini SE, De Jager PL, Calabresi PA. PMID: 31289819.
View in: PubMed Mentions: 5 Fields: Translation: Humans
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Genetic variation across RNA metabolism and cell death gene networks is implicated in the semantic variant of primary progressive aphasia. Sci Rep. 2019 07 26; 9(1):10854.
Bonham LW, Steele NZR, Karch CM, Broce I, Geier EG, Wen NL, Momeni P, Hardy J, Miller ZA, Gorno-Tempini ML, Hess CP, Lewis P, Miller BL, Seeley WW, Manzoni C, Desikan RS, Baranzini SE, Ferrari R, Yokoyama JS. PMID: 31350420.
View in: PubMed Mentions: Fields: Translation: HumansCells
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Integrating biomedical research and electronic health records to create knowledge-based biologically meaningful machine-readable embeddings. Nat Commun. 2019 07 10; 10(1):3045.
Nelson CA, Butte AJ, Baranzini SE. PMID: 31292438.
View in: PubMed Mentions: 6 Fields:
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Aberrant oligodendroglial-vascular interactions disrupt the blood-brain barrier, triggering CNS inflammation. Nat Neurosci. 2019 05; 22(5):709-718.
Niu J, Tsai HH, Hoi KK, Huang N, Yu G, Kim K, Baranzini SE, Xiao L, Chan JR, Fancy SPJ. PMID: 30988524.
View in: PubMed Mentions: 14 Fields: Translation: HumansAnimalsCells
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Recirculating Intestinal IgA-Producing Cells Regulate Neuroinflammation via IL-10. Cell. 2019 Apr 04; 177(2):492-493.
Rojas OL, Pröbstel AK, Porfilio EA, Wang AA, Charabati M, Sun T, Lee DSW, Galicia G, Ramaglia V, Ward LA, Leung LYT, Najafi G, Khaleghi K, Garcillán B, Li A, Besla R, Naouar I, Cao EY, Chiaranunt P, Burrows K, Robinson HG, Allanach JR, Yam J, Luck H, Campbell DJ, Allman D, Brooks DG, Tomura M, Baumann R, Zamvil SS, Bar-Or A, Horwitz MS, Winer DA, Mortha A, Mackay F, Prat A, Osborne LC, Robbins C, Baranzini SE, Gommerman JL. PMID: 30951673.
View in: PubMed Mentions: 6 Fields:
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Silent progression in disease activity-free relapsing multiple sclerosis. Ann Neurol. 2019 05; 85(5):653-666.
Cree BAC, Hollenbach JA, Bove R, Kirkish G, Sacco S, Caverzasi E, Bischof A, Gundel T, Zhu AH, Papinutto N, Stern WA, Bevan C, Romeo A, Goodin DS, Gelfand JM, Graves J, Green AJ, Wilson MR, Zamvil SS, Zhao C, Gomez R, Ragan NR, Rush GQ, Barba P, Santaniello A, Baranzini SE, Oksenberg JR, Henry RG, Hauser SL. PMID: 30851128.
View in: PubMed Mentions: 13 Fields: Translation: Humans
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Insights into microbiome research 6: The role of consortia in studying the role of microbes in health and disease. Mult Scler. 2019 03; 25(3):336-337.
Baranzini SE. PMID: 30801223.
View in: PubMed Mentions: Fields: Translation: Humans
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Insights into microbiome research 5: Mapping is first but function must come next. Mult Scler. 2019 02; 25(2):193-195.
Baranzini SE. PMID: 30799701.
View in: PubMed Mentions: Fields: Translation: Humans
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Selective Estrogen Receptor Modulators Enhance CNS Remyelination Independent of Estrogen Receptors. J Neurosci. 2019 03 20; 39(12):2184-2194.
Rankin KA, Mei F, Kim K, Shen YA, Mayoral SR, Desponts C, Lorrain DS, Green AJ, Baranzini SE, Chan JR, Bove R. PMID: 30696729.
View in: PubMed Mentions: 4 Fields: Translation: AnimalsCells
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Recirculating Intestinal IgA-Producing Cells Regulate Neuroinflammation via IL-10. Cell. 2019 01 24; 176(3):610-624.e18.
Rojas OL, Pröbstel AK, Porfilio EA, Wang AA, Charabati M, Sun T, Lee DSW, Galicia G, Ramaglia V, Ward LA, Leung LYT, Najafi G, Khaleghi K, Garcillán B, Li A, Besla R, Naouar I, Cao EY, Chiaranunt P, Burrows K, Robinson HG, Allanach JR, Yam J, Luck H, Campbell DJ, Allman D, Brooks DG, Tomura M, Baumann R, Zamvil SS, Bar-Or A, Horwitz MS, Winer DA, Mortha A, Mackay F, Prat A, Osborne LC, Robbins C, Baranzini SE, Gommerman JL. PMID: 30612739.
View in: PubMed Mentions: 23 Fields: Translation: HumansAnimalsCells
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Insights into microbiome research 4: The computational analysis. Mult Scler. 2019 01; 25(1):21-22.
Baranzini SE. PMID: 30799699.
View in: PubMed Mentions: Fields: Translation: Humans
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Multiple Sclerosis-Associated Changes in the Composition and Immune Functions of Spore-Forming Bacteria. mSystems. 2018 Nov-Dec; 3(6).
Cekanaviciute E, Pröbstel AK, Thomann A, Runia TF, Casaccia P, Katz Sand I, Crabtree E, Singh S, Morrissey J, Barba P, Gomez R, Knight R, Mazmanian S, Graves J, Cree BAC, Zamvil SS, Baranzini SE. PMID: 30417113.
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Disease-modifying therapies alter gut microbial composition in MS. Neurol Neuroimmunol Neuroinflamm. 2019 01; 6(1):e517.
Katz Sand I, Zhu Y, Ntranos A, Clemente JC, Cekanaviciute E, Brandstadter R, Crabtree-Hartman E, Singh S, Bencosme Y, Debelius J, Knight R, Cree BAC, Baranzini SE, Casaccia P. PMID: 30568995.
View in: PubMed Mentions: 12 Fields: Translation: HumansCells
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Insights into microbiome research 2: Experimental design, sample collection, and shipment. Mult Scler. 2018 10; 24(11):1419-1420.
Baranzini SE. PMID: 30289379.
View in: PubMed Mentions: Fields: Translation: Humans
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Protein network analysis reveals selectively vulnerable regions and biological processes in FTD. Neurol Genet. 2018 Oct; 4(5):e266.
Bonham LW, Steele NZR, Karch CM, Manzoni C, Geier EG, Wen N, Ofori-Kuragu A, Momeni P, Hardy J, Miller ZA, Hess CP, Lewis P, Miller BL, Seeley WW, Baranzini SE, Desikan RS, Ferrari R, Yokoyama JS. PMID: 30283816.
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Insights into microbiome research 3: Who's there versus what are they doing? Mult Scler. 2018 10; 24(12):1541-1542.
Baranzini SE. PMID: 30332350.
View in: PubMed Mentions: Fields: Translation: Humans
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Insights into microbiome research 1: How to choose appropriate controls for a microbiome study in MS? Mult Scler. 2018 09; 24(10):1278-1279.
Baranzini SE. PMID: 30129894.
View in: PubMed Mentions: Fields: Translation: Humans
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Genome sequencing uncovers phenocopies in primary progressive multiple sclerosis. Ann Neurol. 2018 07; 84(1):51-63.
Jia X, Madireddy L, Caillier S, Santaniello A, Esposito F, Comi G, Stuve O, Zhou Y, Taylor B, Kilpatrick T, Martinelli-Boneschi F, Cree BAC, Oksenberg JR, Hauser SL, Baranzini SE. PMID: 29908077.
View in: PubMed Mentions: 2 Fields: Translation: Humans
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Mononuclear cell transcriptome changes associated with dimethyl fumarate in MS. Neurol Neuroimmunol Neuroinflamm. 2018 Jul; 5(4):e470.
Gafson AR, Kim K, Cencioni MT, van Hecke W, Nicholas R, Baranzini SE, Matthews PM. PMID: 30283812.
View in: PubMed Mentions: 1 Fields:
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Correction: Peroxisome proliferator-activated receptor (PPAR)a expression in T cells mediates gender differences in development of T cell-mediated autoimmunity. J Exp Med. 2018 06 04; 215(6):1765.
Dunn SE, Ousman SS, Sobel RA, Zuniga L, Baranzini SE, Youssef S, Crowell A, Loh J, Oksenberg J, Steinman L. PMID: 29773642.
View in: PubMed Mentions: Fields:
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Multiple sclerosis. Lancet. 2018 04 21; 391(10130):1622-1636.
Thompson AJ, Baranzini SE, Geurts J, Hemmer B, Ciccarelli O. PMID: 29576504.
View in: PubMed Mentions: 124 Fields: Translation: HumansCells
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The microbiome and MS: The influence of the microbiota on MS risk and progression-Session chair summary. Mult Scler. 2018 04; 24(5):587-589.
Katz Sand I, Baranzini SE. PMID: 29498302.
View in: PubMed Mentions: Fields: Translation: Humans
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Harnessing electronic medical records to advance research on multiple sclerosis. Mult Scler. 2019 03; 25(3):408-418.
Damotte V, Lizée A, Tremblay M, Agrawal A, Khankhanian P, Santaniello A, Gomez R, Lincoln R, Tang W, Chen T, Lee N, Villoslada P, Hollenbach JA, Bevan CD, Graves J, Bove R, Goodin DS, Green AJ, Baranzini SE, Cree BA, Henry RG, Hauser SL, Gelfand JM, Gourraud PA. PMID: 29310490.
View in: PubMed Mentions: 2 Fields: Translation: Humans
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The Gut Microbiome in Neuromyelitis Optica. Neurotherapeutics. 2018 01; 15(1):92-101.
Zamvil SS, Spencer CM, Baranzini SE, Cree BAC. PMID: 29280091.
View in: PubMed Mentions: 11 Fields: Translation: HumansAnimalsCells
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The Role of the Gut Microbiome in Multiple Sclerosis Risk and Progression: Towards Characterization of the "MS Microbiome". Neurotherapeutics. 2018 01; 15(1):126-134.
Pröbstel AK, Baranzini SE. PMID: 29147991.
View in: PubMed Mentions: 10 Fields: Translation: HumansAnimalsCells
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The era of GWAS is over - Commentary. Mult Scler. 2018 03; 24(3):260-261.
Baranzini SE. PMID: 29251183.
View in: PubMed Mentions: Fields: Translation: Humans
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The Genetics of Multiple Sclerosis: From 0 to 200 in 50 Years. Trends Genet. 2017 12; 33(12):960-970.
Baranzini SE, Oksenberg JR. PMID: 28987266.
View in: PubMed Mentions: 25 Fields: Translation: Humans
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Systematic integration of biomedical knowledge prioritizes drugs for repurposing. Elife. 2017 09 22; 6.
Himmelstein DS, Lizee A, Hessler C, Brueggeman L, Chen SL, Hadley D, Green A, Khankhanian P, Baranzini SE. PMID: 28936969.
View in: PubMed Mentions: 29 Fields: Translation: Humans
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Gut microbiota from multiple sclerosis patients enables spontaneous autoimmune encephalomyelitis in mice. Proc Natl Acad Sci U S A. 2017 10 03; 114(40):10719-10724.
Berer K, Gerdes LA, Cekanaviciute E, Jia X, Xiao L, Xia Z, Liu C, Klotz L, Stauffer U, Baranzini SE, Kümpfel T, Hohlfeld R, Krishnamoorthy G, Wekerle H. PMID: 28893994.
View in: PubMed Mentions: 119 Fields: Translation: HumansAnimalsCells
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Gut bacteria from multiple sclerosis patients modulate human T cells and exacerbate symptoms in mouse models. Proc Natl Acad Sci U S A. 2017 10 03; 114(40):10713-10718.
Cekanaviciute E, Yoo BB, Runia TF, Debelius JW, Singh S, Nelson CA, Kanner R, Bencosme Y, Lee YK, Hauser SL, Crabtree-Hartman E, Sand IK, Gacias M, Zhu Y, Casaccia P, Cree BAC, Knight R, Mazmanian SK, Baranzini SE. PMID: 28893978.
View in: PubMed Mentions: 125 Fields: Translation: HumansAnimalsCells
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Data characterizing the ZMIZ1 molecular phenotype of multiple sclerosis. Data Brief. 2017 Apr; 11:364-370.
Fewings N, Gatt PN, McKay FC, Parnell GP, Schibeci SD, Edwards J, Basuki MA, Goldinger A, Fabis-Pedrini MJ, Kermode AG, Manrique CP, McCauley JL, Nickles D, Baranzini SE, Burke T, Vucic S, Stewart GJ, Booth DR. PMID: 28275670.
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The autoimmune risk gene ZMIZ1 is a vitamin D responsive marker of a molecular phenotype of multiple sclerosis. J Autoimmun. 2017 03; 78:57-69.
Fewings NL, Gatt PN, McKay FC, Parnell GP, Schibeci SD, Edwards J, Basuki MA, Goldinger A, Fabis-Pedrini MJ, Kermode AG, Manrique CP, McCauley JL, Nickles D, Baranzini SE, Burke T, Vucic S, Stewart GJ, Booth DR. PMID: 28063629.
View in: PubMed Mentions: 7 Fields: Translation: HumansCells
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Two missense mutations in SALL4 in a patient with microphthalmia, coloboma, and optic nerve hypoplasia. Ophthalmic Genet. 2017 Jul-Aug; 38(4):371-375.
Ullah E, Wu D, Madireddy L, Lao R, Ling-Fung Tang P, Wan E, Bardakjian T, Kopinsky S, Kwok PY, Schneider A, Baranzini S, Ansar M, Slavotinek A. PMID: 27661448.
View in: PubMed Mentions: 2 Fields: Translation: Humans
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IFN-? orchestrates mesenchymal stem cell plasticity through the signal transducer and activator of transcription 1 and 3 and mammalian target of rapamycin pathways. J Allergy Clin Immunol. 2017 May; 139(5):1667-1676.
Vigo T, Procaccini C, Ferrara G, Baranzini S, Oksenberg JR, Matarese G, Diaspro A, Kerlero de Rosbo N, Uccelli A. PMID: 27670240.
View in: PubMed Mentions: 6 Fields: Translation: HumansAnimalsCells
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Immune cell-specific transcriptional profiling highlights distinct molecular pathways controlled by Tob1 upon experimental autoimmune encephalomyelitis. Sci Rep. 2016 08 22; 6:31603.
Didonna A, Cekanaviciute E, Oksenberg JR, Baranzini SE. PMID: 27546286.
View in: PubMed Mentions: 7 Fields: Translation: AnimalsCells
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Long-term evolution of multiple sclerosis disability in the treatment era. Ann Neurol. 2016 10; 80(4):499-510.
Cree BA, Gourraud PA, Oksenberg JR, Bevan C, Crabtree-Hartman E, Gelfand JM, Goodin DS, Graves J, Green AJ, Mowry E, Okuda DT, Pelletier D, von Büdingen HC, Zamvil SS, Agrawal A, Caillier S, Ciocca C, Gomez R, Kanner R, Lincoln R, Lizee A, Qualley P, Santaniello A, Suleiman L, Bucci M, Panara V, Papinutto N, Stern WA, Zhu AH, Cutter GR, Baranzini S, Henry RG, Hauser SL. PMID: 27464262.
View in: PubMed Mentions: 54 Fields: Translation: Humans
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Gut microbiome analysis in neuromyelitis optica reveals overabundance of Clostridium perfringens. Ann Neurol. 2016 09; 80(3):443-7.
Cree BA, Spencer CM, Varrin-Doyer M, Baranzini SE, Zamvil SS. PMID: 27398819.
View in: PubMed Mentions: 32 Fields: Translation: HumansCells
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Association of HLA Genetic Risk Burden With Disease Phenotypes in Multiple Sclerosis. JAMA Neurol. 2016 07 01; 73(7):795-802.
Isobe N, Keshavan A, Gourraud PA, Zhu AH, Datta E, Schlaeger R, Caillier SJ, Santaniello A, Lizée A, Himmelstein DS, Baranzini SE, Hollenbach J, Cree BA, Hauser SL, Oksenberg JR, Henry RG. PMID: 27244296.
View in: PubMed Mentions: 15 Fields: Translation: Humans
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Meta-analysis of genome-wide association studies reveals genetic overlap between Hodgkin lymphoma and multiple sclerosis. Int J Epidemiol. 2016 06; 45(3):728-40.
Khankhanian P, Cozen W, Himmelstein DS, Madireddy L, Din L, van den Berg A, Matsushita T, Glaser SL, Moré JM, Smedby KE, Baranzini SE, Mack TM, Lizée A, de Sanjosé S, Gourraud PA, Nieters A, Hauser SL, Cocco P, Maynadié M, Foretová L, Staines A, Delahaye-Sourdeix M, Li D, Bhatia S, Melbye M, Onel K, Jarrett R, McKay JD, Oksenberg JR, Hjalgrim H. PMID: 26971321.
View in: PubMed Mentions: 7 Fields: Translation: Humans
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A validated gene regulatory network and GWAS identifies early regulators of T cell-associated diseases. Sci Transl Med. 2015 Nov 11; 7(313):313ra178.
Gustafsson M, Gawel DR, Alfredsson L, Baranzini S, Björkander J, Blomgran R, Hellberg S, Eklund D, Ernerudh J, Kockum I, Konstantinell A, Lahesmaa R, Lentini A, Liljenström HR, Mattson L, Matussek A, Mellergård J, Mendez M, Olsson T, Pujana MA, Rasool O, Serra-Musach J, Stenmarker M, Tripathi S, Viitala M, Wang H, Zhang H, Nestor CE, Benson M. PMID: 26560356.
View in: PubMed Mentions: 18 Fields: Translation: HumansCells
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Assessing the Power of Exome Chips. PLoS One. 2015; 10(10):e0139642.
Page CM, Baranzini SE, Mevik BH, Bos SD, Harbo HF, Andreassen BK. PMID: 26437075.
View in: PubMed Mentions: 5 Fields: Translation: Humans
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A non-synonymous single-nucleotide polymorphism associated with multiple sclerosis risk affects the EVI5 interactome. Hum Mol Genet. 2015 Dec 15; 24(24):7151-8.
Didonna A, Isobe N, Caillier SJ, Li KH, Burlingame AL, Hauser SL, Baranzini SE, Patsopoulos NA, Oksenberg JR. PMID: 26433934.
View in: PubMed Mentions: 5 Fields: Translation: HumansCells
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Class II HLA interactions modulate genetic risk for multiple sclerosis. Nat Genet. 2015 Oct; 47(10):1107-1113.
Moutsianas L, Jostins L, Beecham AH, Dilthey AT, Xifara DK, Ban M, Shah TS, Patsopoulos NA, Alfredsson L, Anderson CA, Attfield KE, Baranzini SE, Barrett J, Binder TMC, Booth D, Buck D, Celius EG, Cotsapas C, D'Alfonso S, Dendrou CA, Donnelly P, Dubois B, Fontaine B, Fugger L, Goris A, Gourraud PA, Graetz C, Hemmer B, Hillert J, Kockum I, Leslie S, Lill CM, Martinelli-Boneschi F, Oksenberg JR, Olsson T, Oturai A, Saarela J, Søndergaard HB, Spurkland A, Taylor B, Winkelmann J, Zipp F, Haines JL, Pericak-Vance MA, Spencer CCA, Stewart G, Hafler DA, Ivinson AJ, Harbo HF, Hauser SL, De Jager PL, Compston A, McCauley JL, Sawcer S, McVean G. PMID: 26343388.
View in: PubMed Mentions: 72 Fields: Translation: Humans
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iCTNet2: integrating heterogeneous biological interactions to understand complex traits. F1000Res. 2015; 4:485.
Wang L, Himmelstein DS, Santaniello A, Parvin M, Baranzini SE. PMID: 26834985.
View in: PubMed Mentions: 2 Fields:
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Genetic contribution to multiple sclerosis risk among Ashkenazi Jews. BMC Med Genet. 2015 Jul 28; 16:55.
Khankhanian P, Matsushita T, Madireddy L, Lizée A, Din L, Moré JM, Gourraud PA, Hauser SL, Baranzini SE, Oksenberg JR. PMID: 26212423.
View in: PubMed Mentions: 2 Fields: Translation: Humans
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Heterogeneous Network Edge Prediction: A Data Integration Approach to Prioritize Disease-Associated Genes. PLoS Comput Biol. 2015 Jul; 11(7):e1004259.
Himmelstein DS, Baranzini SE. PMID: 26158728.
View in: PubMed Mentions: 16 Fields: Translation: HumansAnimalsCells
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Genetic associations with brain cortical thickness in multiple sclerosis. Genes Brain Behav. 2015 Feb; 14(2):217-27.
Matsushita T, Madireddy L, Sprenger T, Khankhanian P, Magon S, Naegelin Y, Caverzasi E, Lindberg RL, Kappos L, Hauser SL, Oksenberg JR, Henry R, Pelletier D, Baranzini SE. PMID: 25684059.
View in: PubMed Mentions: 8 Fields: Translation: Humans
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A robust type I interferon gene signature from blood RNA defines quantitative but not qualitative differences between three major IFNß drugs in the treatment of multiple sclerosis. Hum Mol Genet. 2015 Jun 01; 24(11):3192-205.
Harari D, Orr I, Rotkopf R, Baranzini SE, Schreiber G. PMID: 25721402.
View in: PubMed Mentions: 3 Fields: Translation: HumansCells
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SNP imputation bias reduces effect size determination. Front Genet. 2015; 6:30.
Khankhanian P, Din L, Caillier SJ, Gourraud PA, Baranzini SE. PMID: 25709616.
View in: PubMed Mentions:
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Exome sequencing in 32 patients with anophthalmia/microphthalmia and developmental eye defects. Clin Genet. 2015 Nov; 88(5):468-73.
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iPINBPA: an integrative network-based functional module discovery tool for genome-wide association studies. Pac Symp Biocomput. 2015; 255-66.
Wang L, Mousavi P, Baranzini SE. PMID: 25592586.
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Whole genome sequences of 2 octogenarians with sustained cognitive abilities. Neurobiol Aging. 2015 Mar; 36(3):1435-8.
Nickles D, Madireddy L, Patel N, Isobe N, Miller BL, Baranzini SE, Kramer JH, Oksenberg JR. PMID: 25618617.
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Interferon-beta affects mitochondrial activity in CD4+ lymphocytes: Implications for mechanism of action in multiple sclerosis. Mult Scler. 2015 Sep; 21(10):1262-70.
Haghikia A, Faissner S, Pappas D, Pula B, Akkad DA, Arning L, Ruhrmann S, Duscha A, Gold R, Baranzini SE, Malhotra S, Montalban X, Comabella M, Chan A. PMID: 25480861.
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Prognostic biomarkers of IFNb therapy in multiple sclerosis patients. Mult Scler. 2015 Jun; 21(7):894-904.
Baranzini SE, Madireddy LR, Cromer A, D'Antonio M, Lehr L, Beelke M, Farmer P, Battaglini M, Caillier SJ, Stromillo ML, De Stefano N, Monnet E, Cree BA. PMID: 25392319.
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Modules, networks and systems medicine for understanding disease and aiding diagnosis. Genome Med. 2014; 6(10):82.
Gustafsson M, Nestor CE, Zhang H, Barabási AL, Baranzini S, Brunak S, Chung KF, Federoff HJ, Gavin AC, Meehan RR, Picotti P, Pujana MÀ, Rajewsky N, Smith KG, Sterk PJ, Villoslada P, Benson M. PMID: 25473422.
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Precision medicine in chronic disease management: The multiple sclerosis BioScreen. Ann Neurol. 2014 Nov; 76(5):633-42.
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PINBPA: cytoscape app for network analysis of GWAS data. Bioinformatics. 2015 Jan 15; 31(2):262-4.
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Rituximab efficiently depletes increased CD20-expressing T cells in multiple sclerosis patients. J Immunol. 2014 Jul 15; 193(2):580-586.
Palanichamy A, Jahn S, Nickles D, Derstine M, Abounasr A, Hauser SL, Baranzini SE, Leppert D, von Büdingen HC. PMID: 24928997.
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The role of antiproliferative gene Tob1 in the immune system. Clin Exp Neuroimmunol. 2014 Jun 01; 5(2):132-136.
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Blood miRNA expression pattern is a possible risk marker for natalizumab-associated progressive multifocal leukoencephalopathy in multiple sclerosis patients. Mult Scler. 2014 Dec; 20(14):1851-9.
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Astrocyte-encoded positional cues maintain sensorimotor circuit integrity. Nature. 2014 May 08; 509(7499):189-94.
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Parallel states of pathological Wnt signaling in neonatal brain injury and colon cancer. Nat Neurosci. 2014 Apr; 17(4):506-12.
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Naive CD4 T-cell activation identifies MS patients having rapid transition to progressive MS. Neurology. 2014 Feb 25; 82(8):681-90.
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A gene pathway analysis highlights the role of cellular adhesion molecules in multiple sclerosis susceptibility. Genes Immun. 2014 Mar; 15(2):126-32.
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The autoimmune disease-associated transcription factors EOMES and TBX21 are dysregulated in multiple sclerosis and define a molecular subtype of disease. Clin Immunol. 2014 Mar; 151(1):16-24.
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Symposium 2-1 The autoimmunome: Similarities and differences among genetic susceptibility to common immune-related diseases. Nihon Rinsho Meneki Gakkai Kaishi. 2014; 37(4):261.
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Sequencing of the IL6 gene in a case-control study of cerebral palsy in children. BMC Med Genet. 2013 Dec 07; 14:126.
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Gene expression profiling in MS: a fulfilled promise? Mult Scler. 2013 Dec; 19(14):1813-4.
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Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. Nat Genet. 2013 Nov; 45(11):1353-60.
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Expression profiling of Aldh1l1-precursors in the developing spinal cord reveals glial lineage-specific genes and direct Sox9-Nfe2l1 interactions. Glia. 2013 Sep; 61(9):1518-32.
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Tob1 plays a critical role in the activation of encephalitogenic T cells in CNS autoimmunity. J Exp Med. 2013 Jul 01; 210(7):1301-9.
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Opposite roles of NMDA receptors in relapsing and primary progressive multiple sclerosis. PLoS One. 2013; 8(6):e67357.
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Blood RNA profiling in a large cohort of multiple sclerosis patients and healthy controls. Hum Mol Genet. 2013 Oct 15; 22(20):4194-205.
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Network-based multiple sclerosis pathway analysis with GWAS data from 15,000 cases and 30,000 controls. Am J Hum Genet. 2013 Jun 06; 92(6):854-65.
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Hippocampal demyelination and memory dysfunction are associated with increased levels of the neuronal microRNA miR-124 and reduced AMPA receptors. Ann Neurol. 2013 May; 73(5):637-45.
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A genome-wide association study of brain lesion distribution in multiple sclerosis. Brain. 2013 Apr; 136(Pt 4):1012-24.
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Transcriptional expression patterns triggered by chemically distinct neuroprotective molecules. Neuroscience. 2012 Dec 13; 226:10-20.
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In depth comparison of an individual's DNA and its lymphoblastoid cell line using whole genome sequencing. BMC Genomics. 2012 Sep 14; 13:477.
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The genetics of multiple sclerosis: an up-to-date review. Immunol Rev. 2012 Jul; 248(1):87-103.
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Janus-like opposing roles of CD47 in autoimmune brain inflammation in humans and mice. J Exp Med. 2012 Jul 02; 209(7):1325-34.
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Detection of identity by descent using next-generation whole genome sequencing data. BMC Bioinformatics. 2012 Jun 06; 13:121.
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Genetics of multiple sclerosis: swimming in an ocean of data. Curr Opin Neurol. 2012 Jun; 25(3):239-45.
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Data integration and systems biology approaches for biomarker discovery: challenges and opportunities for multiple sclerosis. J Neuroimmunol. 2012 Jul 15; 248(1-2):58-65.
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iCTNet: a Cytoscape plugin to produce and analyze integrative complex traits networks. BMC Bioinformatics. 2011 Sep 26; 12:380.
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Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature. 2011 Aug 10; 476(7359):214-9.
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Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination. Nat Neurosci. 2011 Jun 26; 14(8):1009-16.
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Manitoba-oculo-tricho-anal (MOTA) syndrome is caused by mutations in FREM1. J Med Genet. 2011 Jun; 48(6):375-82.
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Functional energetics of CD4+-cellular immunity in monoclonal antibody-associated progressive multifocal leukoencephalopathy in autoimmune disorders. PLoS One. 2011 Apr 20; 6(4):e18506.
Haghikia A, Perrech M, Pula B, Ruhrmann S, Potthoff A, Brockmeyer NH, Goelz S, Wiendl H, Lindå H, Ziemssen T, Baranzini SE, Käll TB, Bengel D, Olsson T, Gold R, Chan A. PMID: 21533133.
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Modeling the cumulative genetic risk for multiple sclerosis from genome-wide association data. Genome Med. 2011 Jan 18; 3(1):3.
Wang JH, Pappas D, De Jager PL, Pelletier D, de Bakker PI, Kappos L, Polman CH, Chibnik LB, Hafler DA, Matthews PM, Hauser SL, Baranzini SE, Oksenberg JR. PMID: 21244703.
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Revealing the genetic basis of multiple sclerosis: are we there yet? Curr Opin Genet Dev. 2011 Jun; 21(3):317-24.
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Dynamic, multi-level network models of clinical trials. Pac Symp Biocomput. 2011; 38-49.
Sorani MD, Manley GT, Claude Hemphill J, Baranzini SE. PMID: 21121031.
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Myelin regeneration: a recapitulation of development? Annu Rev Neurosci. 2011; 34:21-43.
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Genetic variation in the odorant receptors family 13 and the mhc loci influence mate selection in a multiple sclerosis dataset. BMC Genomics. 2010 Nov 10; 11:626.
Khankhanian P, Gourraud PA, Caillier SJ, Santaniello A, Hauser SL, Baranzini SE, Oksenberg JR. PMID: 21067613.
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Genetic variation influences glutamate concentrations in brains of patients with multiple sclerosis. Brain. 2010 Sep; 133(9):2603-11.
Baranzini SE, Srinivasan R, Khankhanian P, Okuda DT, Nelson SJ, Matthews PM, Hauser SL, Oksenberg JR, Pelletier D. PMID: 20802204.
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Multiple sclerosis genetics--is the glass half full, or half empty? Nat Rev Neurol. 2010 Aug; 6(8):429-37.
Oksenberg JR, Baranzini SE. PMID: 20625377.
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Genome, epigenome and RNA sequences of monozygotic twins discordant for multiple sclerosis. Nature. 2010 Apr 29; 464(7293):1351-6.
Baranzini SE, Mudge J, van Velkinburgh JC, Khankhanian P, Khrebtukova I, Miller NA, Zhang L, Farmer AD, Bell CJ, Kim RW, May GD, Woodward JE, Caillier SJ, McElroy JP, Gomez R, Pando MJ, Clendenen LE, Ganusova EE, Schilkey FD, Ramaraj T, Khan OA, Huntley JJ, Luo S, Kwok PY, Wu TD, Schroth GP, Oksenberg JR, Hauser SL, Kingsmore SF. PMID: 20428171.
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The genetics of autoimmune diseases: a networked perspective. Curr Opin Immunol. 2009 Dec; 21(6):596-605.
Baranzini SE. PMID: 19896815.
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Differential micro RNA expression in PBMC from multiple sclerosis patients. PLoS One. 2009 Jul 20; 4(7):e6309.
Otaegui D, Baranzini SE, Armañanzas R, Calvo B, Muñoz-Culla M, Khankhanian P, Inza I, Lozano JA, Castillo-Triviño T, Asensio A, Olaskoaga J, López de Munain A. PMID: 19617918.
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Longitudinal system-based analysis of transcriptional responses to type I interferons. Physiol Genomics. 2009 Aug 07; 38(3):362-71.
Pappas DJ, Coppola G, Gabatto PA, Gao F, Geschwind DH, Oksenberg JR, Baranzini SE. PMID: 19531577.
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Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. Nat Genet. 2009 Jul; 41(7):776-82.
De Jager PL, Jia X, Wang J, de Bakker PI, Ottoboni L, Aggarwal NT, Piccio L, Raychaudhuri S, Tran D, Aubin C, Briskin R, Romano S, Baranzini SE, McCauley JL, Pericak-Vance MA, Haines JL, Gibson RA, Naeglin Y, Uitdehaag B, Matthews PM, Kappos L, Polman C, McArdle WL, Strachan DP, Evans D, Cross AH, Daly MJ, Compston A, Sawcer SJ, Weiner HL, Hauser SL, Hafler DA, Oksenberg JR. PMID: 19525953.
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Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS. Genes Dev. 2009 Jul 01; 23(13):1571-85.
Fancy SP, Baranzini SE, Zhao C, Yuk DI, Irvine KA, Kaing S, Sanai N, Franklin RJ, Rowitch DH. PMID: 19515974.
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Pathway and network-based analysis of genome-wide association studies in multiple sclerosis. Hum Mol Genet. 2009 Jun 01; 18(11):2078-90.
Baranzini SE, Galwey NW, Wang J, Khankhanian P, Lindberg R, Pelletier D, Wu W, Uitdehaag BM, Kappos L, Polman CH, Matthews PM, Hauser SL, Gibson RA, Oksenberg JR, Barnes MR. PMID: 19286671.
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Systems biology and its application to the understanding of neurological diseases. Ann Neurol. 2009 Feb; 65(2):124-39.
Villoslada P, Steinman L, Baranzini SE. PMID: 19260029.
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Incidental MRI anomalies suggestive of multiple sclerosis: the radiologically isolated syndrome. Neurology. 2009 Mar 03; 72(9):800-5.
Okuda DT, Mowry EM, Beheshtian A, Waubant E, Baranzini SE, Goodin DS, Hauser SL, Pelletier D. PMID: 19073949.
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Genotype-Phenotype correlations in multiple sclerosis: HLA genes influence disease severity inferred by 1HMR spectroscopy and MRI measures. Brain. 2009 Jan; 132(Pt 1):250-9.
Okuda DT, Srinivasan R, Oksenberg JR, Goodin DS, Baranzini SE, Beheshtian A, Waubant E, Zamvil SS, Leppert D, Qualley P, Lincoln R, Gomez R, Caillier S, George M, Wang J, Nelson SJ, Cree BA, Hauser SL, Pelletier D. PMID: 19022862.
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Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. Hum Mol Genet. 2009 Feb 15; 18(4):767-78.
Baranzini SE, Wang J, Gibson RA, Galwey N, Naegelin Y, Barkhof F, Radue EW, Lindberg RL, Uitdehaag BM, Johnson MR, Angelakopoulou A, Hall L, Richardson JC, Prinjha RK, Gass A, Geurts JJ, Kragt J, Sombekke M, Vrenken H, Qualley P, Lincoln RR, Gomez R, Caillier SJ, George MF, Mousavi H, Guerrero R, Okuda DT, Cree BA, Green AJ, Waubant E, Goodin DS, Pelletier D, Matthews PM, Hauser SL, Kappos L, Polman CH, Oksenberg JR. PMID: 19010793.
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Changes in matrix metalloproteinases and their inhibitors during interferon-beta treatment in multiple sclerosis. Clin Immunol. 2009 Feb; 130(2):145-50.
Comabella M, Río J, Espejo C, Ruiz de Villa M, Al-Zayat H, Nos C, Deisenhammer F, Baranzini SE, Nonell L, López C, Julià E, Oksenberg JR, Montalban X. PMID: 18945642.
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Uncoupling the roles of HLA-DRB1 and HLA-DRB5 genes in multiple sclerosis. J Immunol. 2008 Oct 15; 181(8):5473-80.
Caillier SJ, Briggs F, Cree BA, Baranzini SE, Fernandez-Viña M, Ramsay PP, Khan O, Royal W, Hauser SL, Barcellos LF, Oksenberg JR. PMID: 18832704.
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Abrogation of T cell quiescence characterizes patients at high risk for multiple sclerosis after the initial neurological event. Proc Natl Acad Sci U S A. 2008 Aug 19; 105(33):11839-44.
Corvol JC, Pelletier D, Henry RG, Caillier SJ, Wang J, Pappas D, Casazza S, Okuda DT, Hauser SL, Oksenberg JR, Baranzini SE. PMID: 18689680.
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The genetics of multiple sclerosis: SNPs to pathways to pathogenesis. Nat Rev Genet. 2008 Jul; 9(7):516-26.
Oksenberg JR, Baranzini SE, Sawcer S, Hauser SL. PMID: 18542080.
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A framework and mechanistically focused, in silico method for enabling rational translational research. Summit Transl Bioinform. 2008 Mar 01; 2008:46-50.
Hunt CA, Baranzini S, Matthay MA, Park S. PMID: 21347126.
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Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets. Nature. 2008 Feb 28; 451(7182):1076-81.
Han MH, Hwang SI, Roy DB, Lundgren DH, Price JV, Ousman SS, Fernald GH, Gerlitz B, Robinson WH, Baranzini SE, Grinnell BW, Raine CS, Sobel RA, Han DK, Steinman L. PMID: 18278032.
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Evidence for association of chromosome 10 open reading frame (C10orf27) gene polymorphisms and multiple sclerosis. Mult Scler. 2008 Apr; 14(3):412-4.
Goertsches R, Baranzini SE, Morcillo C, Nos C, Camiña M, Oksenberg JR, Montalban X, Comabella M. PMID: 18208870.
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Genome-wide pharmacogenomic analysis of the response to interferon beta therapy in multiple sclerosis. Arch Neurol. 2008 Mar; 65(3):337-44.
Byun E, Caillier SJ, Montalban X, Villoslada P, Fernández O, Brassat D, Comabella M, Wang J, Barcellos LF, Baranzini SE, Oksenberg JR. PMID: 18195134.
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Increased transcriptional activity of milk-related genes following the active phase of experimental autoimmune encephalomyelitis and multiple sclerosis. J Immunol. 2007 Sep 15; 179(6):4074-82.
Otaegui D, Mostafavi S, Bernard CC, Lopez de Munain A, Mousavi P, Oksenberg JR, Baranzini SE. PMID: 17785846.
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Quantitative longitudinal analysis of T cell receptor repertoire expression in HIV-infected patients on antiretroviral and interleukin-2 therapy. AIDS Res Hum Retroviruses. 2007 May; 23(5):741-7.
Sriram U, Wong M, Caillier SJ, Hecht FM, Elkins MK, Levy JA, Oksenberg JR, Baranzini SE. PMID: 17531001.
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Genome-wide network analysis reveals the global properties of IFN-beta immediate transcriptional effects in humans. J Immunol. 2007 Apr 15; 178(8):5076-85.
Fernald GH, Knott S, Pachner A, Caillier SJ, Narayan K, Oksenberg JR, Mousavi P, Baranzini SE. PMID: 17404290.
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The molecular signature of therapeutic mesenchymal stem cells exposes the architecture of the hematopoietic stem cell niche synapse. BMC Genomics. 2007 Mar 06; 8:65.
Pedemonte E, Benvenuto F, Casazza S, Mancardi G, Oksenberg JR, Uccelli A, Baranzini SE. PMID: 17341312.
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Peroxisome proliferator-activated receptor (PPAR)alpha expression in T cells mediates gender differences in development of T cell-mediated autoimmunity. J Exp Med. 2007 Feb 19; 204(2):321-30.
Dunn SE, Ousman SS, Sobel RA, Zuniga L, Baranzini SE, Youssef S, Crowell A, Loh J, Oksenberg J, Steinman L. PMID: 17261635.
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Systems-based medicine approaches to understand and treat complex diseases. The example of multiple sclerosis. Autoimmunity. 2006 Dec; 39(8):651-62.
Baranzini SE. PMID: 17178562.
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Heterogeneity at the HLA-DRB1 locus and risk for multiple sclerosis. Hum Mol Genet. 2006 Sep 15; 15(18):2813-24.
Barcellos LF, Sawcer S, Ramsay PP, Baranzini SE, Thomson G, Briggs F, Cree BC, Begovich AB, Villoslada P, Montalban X, Uccelli A, Savettieri G, Lincoln RR, DeLoa C, Haines JL, Pericak-Vance MA, Compston A, Hauser SL, Oksenberg JR. PMID: 16905561.
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Predictive modeling of therapy response in multiple sclerosis using gene expression data. Conf Proc IEEE Eng Med Biol Soc. 2006; 2006:5519-22.
Mostafavi S, Baranzini S, Oksernberg J, Mousavi P. PMID: 17946311.
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Mapping gene activity in complex disorders: Integration of expression and genomic scans for multiple sclerosis. J Neuroimmunol. 2005 Oct; 167(1-2):157-69.
Fernald GH, Yeh RF, Hauser SL, Oksenberg JR, Baranzini SE. PMID: 16129498.
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Modular transcriptional activity characterizes the initiation and progression of autoimmune encephalomyelitis. J Immunol. 2005 Jun 01; 174(11):7412-22.
Baranzini SE, Bernard CC, Oksenberg JR. PMID: 15905590.
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Genomics and new targets for multiple sclerosis. Pharmacogenomics. 2005 Mar; 6(2):151-61.
Baranzini SE, Oksenberg JR. PMID: 15882133.
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Longitudinal analysis of B cell repertoire and antibody gene rearrangements during early HIV infection. Genes Immun. 2005 Feb; 6(1):66-9.
Elkins MK, Vittinghoff E, Baranzini SE, Hecht FM, Sriram U, Busch MP, Levy JA, Oksenberg JR. PMID: 15538390.
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Transcription-based prediction of response to IFNbeta using supervised computational methods. PLoS Biol. 2005 Jan; 3(1):e2.
Baranzini SE, Mousavi P, Rio J, Caillier SJ, Stillman A, Villoslada P, Wyatt MM, Comabella M, Greller LD, Somogyi R, Montalban X, Oksenberg JR. PMID: 15630474.
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Gene expression profiling in neurological disorders: toward a systems-level understanding of the brain. Neuromolecular Med. 2004; 6(1):31-51.
Baranzini SE. PMID: 15781975.
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Mapping multiple sclerosis susceptibility to the HLA-DR locus in African Americans. Am J Hum Genet. 2004 Jan; 74(1):160-7.
Oksenberg JR, Barcellos LF, Cree BA, Baranzini SE, Bugawan TL, Khan O, Lincoln RR, Swerdlin A, Mignot E, Lin L, Goodin D, Erlich HA, Schmidt S, Thomson G, Reich DE, Pericak-Vance MA, Haines JL, Hauser SL. PMID: 14669136.
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Dynamic regulation of alternative ATP-binding cassette transporter A1 transcripts. Biochem Biophys Res Commun. 2003 Jun 27; 306(2):463-8.
Huuskonen J, Abedin M, Vishnu M, Pullinger CR, Baranzini SE, Kane JP, Fielding PE, Fielding CJ. PMID: 12804586.
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Osteopontin polymorphisms and disease course in multiple sclerosis. Genes Immun. 2003 Jun; 4(4):312-5.
Caillier S, Barcellos LF, Baranzini SE, Swerdlin A, Lincoln RR, Steinman L, Martin E, Haines JL, Pericak-Vance M, Hauser SL, Oksenberg JR. PMID: 12761568.
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Direct deletion analysis in two Duchenne muscular dystrophy symptomatic females using polymorphic dinucleotide (CA)n loci within the dystrophin gene. J Biochem Mol Biol. 2003 Mar 31; 36(2):179-84.
Giliberto F, Ferreiro V, Dalamón V, Surace E, Cotignola J, Esperante S, Borelina D, Baranzini S, Szijan I. PMID: 12689516.
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Pharmacogenomic analysis of interferon receptor polymorphisms in multiple sclerosis. Genes Immun. 2003 Mar; 4(2):147-52.
Sriram U, Barcellos LF, Villoslada P, Rio J, Baranzini SE, Caillier S, Stillman A, Hauser SL, Montalban X, Oksenberg JR. PMID: 12618863.
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Large-scale gene-expression studies and the challenge of multiple sclerosis. Genome Biol. 2002 Sep 16; 3(10):reviews1027.
Baranzini SE, Hauser SL. PMID: 12372148.
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The HLA locus and multiple sclerosis in Spain. Role in disease susceptibility, clinical course and response to interferon-beta. J Neuroimmunol. 2002 Sep; 130(1-2):194-201.
Villoslada P, Barcellos LF, Rio J, Begovich AB, Tintore M, Sastre-Garriga J, Baranzini SE, Casquero P, Hauser SL, Montalban X, Oksenberg JR. PMID: 12225902.
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Gene expression analysis reveals altered brain transcription of glutamate receptors and inflammatory genes in a patient with chronic focal (Rasmussen's) encephalitis. J Neuroimmunol. 2002 Jul; 128(1-2):9-15.
Baranzini SE, Laxer K, Bollen A, Oksenberg JR. PMID: 12098505.
View in: PubMed Mentions: 6 Fields: Translation: HumansCells
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Analysis of antibody gene rearrangement, usage, and specificity in chronic focal encephalitis. Neurology. 2002 Mar 12; 58(5):709-16.
Baranzini SE, Laxer K, Saketkhoo R, Elkins MK, Parent JM, Mantegazza R, Oksenberg JR. PMID: 11889232.
View in: PubMed Mentions: 6 Fields: Translation: HumansAnimalsCells
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New insights into the genetics of multiple sclerosis. J Rehabil Res Dev. 2002 Mar-Apr; 39(2):201-9.
Baranzini SE, Oksenberg JR, Hauser SL. PMID: 12051464.
View in: PubMed Mentions: 2 Fields: Translation: Humans
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The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease. Science. 2001 Nov 23; 294(5547):1731-5.
Chabas D, Baranzini SE, Mitchell D, Bernard CC, Rittling SR, Denhardt DT, Sobel RA, Lock C, Karpuj M, Pedotti R, Heller R, Oksenberg JR, Steinman L. PMID: 11721059.
View in: PubMed Mentions: 226 Fields: Translation: HumansAnimalsCells
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Multiple sclerosis: genomic rewards. J Neuroimmunol. 2001 Feb 15; 113(2):171-84.
Oksenberg JR, Baranzini SE, Barcellos LF, Hauser SL. PMID: 11164900.
View in: PubMed Mentions: 17 Fields: Translation: Humans
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Transcriptional analysis of multiple sclerosis brain lesions reveals a complex pattern of cytokine expression. J Immunol. 2000 Dec 01; 165(11):6576-82.
Baranzini SE, Elfstrom C, Chang SY, Butunoi C, Murray R, Higuchi R, Oksenberg JR. PMID: 11086101.
View in: PubMed Mentions: 26 Fields: Translation: HumansCells
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B cell repertoire diversity and clonal expansion in multiple sclerosis brain lesions. J Immunol. 1999 Nov 01; 163(9):5133-44.
Baranzini SE, Jeong MC, Butunoi C, Murray RS, Bernard CC, Oksenberg JR. PMID: 10528220.
View in: PubMed Mentions: 85 Fields: Translation: HumansCells
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Carrier detection in Duchenne and Becker muscular dystrophy Argentine families. Clin Genet. 1998 Dec; 54(6):503-11.
Baranzini SE, Giliberto F, Dalamon V, Barreiro C, García-Erro M, Grippo J, Szijan I. PMID: 9894797.
View in: PubMed Mentions: Fields: Translation: HumansCells
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Deletion patterns in Argentine patients with Duchenne and Becker muscular dystrophy. Neurol Res. 1998 Jul; 20(5):409-414.
Baranzini SE, Giliberto F, Herrera M, Bernath V, Barreiro C, Garcia Erro M, Grippo J, Szijan I. PMID: 9664586.
View in: PubMed Mentions: Fields: Translation: HumansCTClinical Trials
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Clinical, cytogenetic, and molecular testing of Argentine patients with retinoblastoma. J AAPOS. 1998 Apr; 2(2):102-7.
Arbetman A, Abdala M, Fandiño A, Herrera J, Baranzini S, Borelina D, Parma D, Manzitti J, Barreiro C, Giliberto F, Szijan I. PMID: 10530971.
View in: PubMed Mentions: 2 Fields: Translation: HumansCells
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Four new polymorphisms in the human dystrophin gene from an Argentinian population. Muscle Nerve. 1997 Nov; 20(11):1451-3.
Baranzini SE, Lenk U, Szijan I, Speer A. PMID: 9342163.
View in: PubMed Mentions: Fields: Translation: HumansCells
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Patient with an Xp21 contiguous gene deletion syndrome in association with agenesis of the corpus callosum. Am J Med Genet. 1997 Jun 13; 70(3):216-21.
Baranzini SE, del Rey G, Nigro N, Szijan I, Chamoles N, Cresto JC. PMID: 9188656.
View in: PubMed Mentions: 1 Fields: Translation: HumansCells
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A new point mutation (M313T) in the thyroid hormone receptor beta gene in a patient with resistance to thyroid hormone. Thyroid. 1997 Feb; 7(1):43-4.
di Fulvio M, Chiesa AE, Baranzini SE, Gruñiero-Papendieck L, Masini-Repiso AM, Targovnik HM. PMID: 9086569.
View in: PubMed Mentions: 4 Fields: Translation: Humans
This graph shows the total number of publications by year. To see the data as text, click here.
This graph shows the total number of publications by year. To return to the graph, click here.
Year | Publications |
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1997 | 3 | 1998 | 3 | 1999 | 1 | 2000 | 1 | 2001 | 2 | 2002 | 5 | 2003 | 5 | 2004 | 2 | 2005 | 4 | 2006 | 3 | 2007 | 5 | 2008 | 11 | 2009 | 7 | 2010 | 4 | 2011 | 9 | 2012 | 7 | 2013 | 10 | 2014 | 15 | 2015 | 12 | 2016 | 7 | 2017 | 7 | 2018 | 14 | 2019 | 11 | 2020 | 9 | 2021 | 1 |
This graph shows the number and percent of publications by field.
Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications.
Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written.
To see the data as text, click here.
This graph shows the number and percent of publications by field.
Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications.
Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written.
To see the data as text, click here.
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