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Sergio Baranzini, PhD

Address675 Nelson Rising Lane
San Francisco CA 94158
Phone415-502-6865
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    Collapse Biography 
    Collapse Education and Training
    University of Buenos Aires, ArgentinaBS/MS1992Biochemistry/Biotechnology
    University of Buenos Aires, ArgentinaPhD1997Biochemistry
    University of California, San FranciscoPostdoctoral Fellow2001Neurogenetics

    Collapse Overview 
    Collapse Overview
    Sergio E. Baranzini earned his degree in clinical biochemistry from the University of Buenos Aires, Argentina, in 1992. He graduated from the same institution in 1997 obtaining a PhD with honors in human molecular genetics. The subject of his PhD thesis was the characterization of genetic mutations leading to Duchenne’s muscular dystrophy. Dr. Baranzini then moved to the University of California at San Francisco to specialize in the analysis of complex hereditary diseases, in particular multiple sclerosis. During his postdoctoral stay in UCSF Dr. Baranzini employed state-of-the art methods to explore MS pathogenesis, including immunology, molecular biology, genomics and bioinformatics. Since 2003 Dr. Baranzini is faculty in the Department of Neurology at UCSF, where he currently holds the title of Associate Professor In-Residence. His research involves the large throughout analysis of samples from MS patients to characterize the activity of genes during: i) different stages of the disease (i.e. remission vs. relapse), ii) differential response to treatment (i.e. good responders vs. poor responders), and iii) disease progression (i.e. benign vs. severe). In addition Dr. Baranzini is collaborating with several interdisciplinary teams worldwide to integrate all the available knowledge obtained in different research domains in an approach known as systems biology. Dr Baranzini’s current research involves immunological studies using the EAE model, sequencing of whole genomes and transcriptomes from patients with multiple sclerosis and developing bioinformatics tools to integrate this information with that coming from other high throughput technologies. Dr Baranzini uses a combination of “wet lab” methods including DNA microarrays, proteomics, and laser capture microdissection, in combination with “dry lab” analytical approaches encompassing bioinformatics, complexity theory, and mathematical modeling.
    Dr. Baranzini has published his research on MS in several top-tier journals like Science, Nature, PNAS, J Immunol, and PLos Biol. He is a member of the American Association of Immunologists, and an elected member of the American Neurological Association. He also serves as an ad-hoc reviewer for many specialized journals.


    Collapse Research 
    Collapse Research Activities and Funding
    Post GWAS approach to identify cell-specific genetic pathways underlying MS risk
    NIH R01NS088155Sep 15, 2014 - Jul 31, 2019
    Role: Principal Investigator
    EXTENSIVE SEARCH FOR AN X-LINKED ACC GENE
    NIH F05NS010448Mar 1, 1998
    Role: Principal Investigator

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    Collapse In The News

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Fewings N, Gatt PN, McKay FC, Parnell GP, Schibeci SD, Edwards J, Basuki MA, Goldinger A, Fabis-Pedrini MJ, Kermode AG, Manrique CP, McCauley JL, Nickles D, Baranzini S, Burke T, Vucic S, Stewart GJ, Booth DR. Data characterizing the ZMIZ1 molecular phenotype of multiple sclerosis. Data Brief. 2017 Apr; 11:364-370. PMID: 28275670.
      View in: PubMed
    2. Fewings NL, Gatt PN, McKay FC, Parnell GP, Schibeci SD, Edwards J, Basuki MA, Goldinger A, Fabis-Pedrini MJ, Kermode AG, Manrique CP, McCauley JL, Nickles D, Baranzini S, Burke T, Vucic S, Stewart GJ, Booth DR. The autoimmune risk gene ZMIZ1 is a vitamin D responsive marker of a molecular phenotype of multiple sclerosis. J Autoimmun. 2017 Jan 04. PMID: 28063629.
      View in: PubMed
    3. Ullah E, Wu D, Madireddy L, Lao R, Ling-Fung Tang P, Wan E, Bardakjian T, Kopinsky S, Kwok PY, Schneider A, Baranzini S, Ansar M, Slavotinek A, et al. Two missense mutations in SALL4 in a patient with microphthalmia, coloboma, and optic nerve hypoplasia. Ophthalmic Genet. 2016 Sep 23; 1-5. PMID: 27661448.
      View in: PubMed
    4. Vigo T, Procaccini C, Ferrara G, Baranzini S, Oksenberg JR, Matarese G, Diaspro A, Kerlero de Rosbo N, Uccelli A. IFN-? orchestrates mesenchymal stem cell plasticity through the signal transducer and activator of transcription 1 and 3 and mammalian target of rapamycin pathways. J Allergy Clin Immunol. 2016 Sep 23. PMID: 27670240.
      View in: PubMed
    5. Didonna A, Cekanaviciute E, Oksenberg JR, Baranzini S. Immune cell-specific transcriptional profiling highlights distinct molecular pathways controlled by Tob1 upon experimental autoimmune encephalomyelitis. Sci Rep. 2016; 6:31603. PMID: 27546286.
      View in: PubMed
    6. Cree BA, Spencer CM, Varrin-Doyer M, Baranzini S, Zamvil SS. Gut microbiome analysis in neuromyelitis optica reveals overabundance of Clostridium perfringens. Ann Neurol. 2016 Sep; 80(3):443-7. PMID: 27398819.
      View in: PubMed
    7. Cree B, Gourraud PA, Oksenberg JR, Bevan C, Crabtree-Hartman E, Gelfand JM, Goodin DS, Graves J, Green AJ, Mowry E, Okuda DT, Pelletier D, von Büdingen HC, Zamvil SS, Agrawal A, Caillier S, Ciocca C, Gomez R, Kanner R, Lincoln R, Lizee A, Qualley P, Santaniello A, Suleiman L, Bucci M, Panara V, Papinutto N, Stern WA, Zhu AH, Cutter GR, Baranzini S, Henry RG, Hauser SL, et al. Long-term evolution of multiple sclerosis disability in the treatment era. Ann Neurol. 2016 Jul 27. PMID: 27464262.
      View in: PubMed
    8. Khankhanian P, Cozen W, Himmelstein DS, Madireddy L, Din L, van den Berg A, Matsushita T, Glaser SL, Moré JM, Smedby KE, Baranzini S, Mack TM, Lizée A, de Sanjosé S, Gourraud PA, Nieters A, Hauser SL, Cocco P, Maynadié M, Foretová L, Staines A, Delahaye-Sourdeix M, Li D, Bhatia S, Melbye M, Onel K, Jarrett R, McKay JD, Oksenberg JR, Hjalgrim H. Meta-analysis of genome-wide association studies reveals genetic overlap between Hodgkin lymphoma and multiple sclerosis. Int J Epidemiol. 2016 Jun; 45(3):728-40. PMID: 26971321.
      View in: PubMed
    9. Gustafsson M, Gawel DR, Alfredsson L, Baranzini S, Björkander J, Blomgran R, Hellberg S, Eklund D, Ernerudh J, Kockum I, Konstantinell A, Lahesmaa R, Lentini A, Liljenström HR, Mattson L, Matussek A, Mellergård J, Mendez M, Olsson T, Pujana MA, Rasool O, Serra-Musach J, Stenmarker M, Tripathi S, Viitala M, Wang H, Zhang H, Nestor CE, Benson M. A validated gene regulatory network and GWAS identifies early regulators of T cell-associated diseases. Sci Transl Med. 2015 Nov 11; 7(313):313ra178. PMID: 26560356.
      View in: PubMed
    10. Page CM, Baranzini S, Mevik BH, Bos SD, Harbo HF, Andreassen BK. Assessing the Power of Exome Chips. PLoS One. 2015; 10(10):e0139642. PMID: 26437075; PMCID: PMC4593624.
      View in: PubMed, PubMed Central
    11. Didonna A, Isobe N, Caillier SJ, Li KH, Burlingame AL, Hauser SL, Baranzini S, Patsopoulos NA, Oksenberg JR. A non-synonymous single-nucleotide polymorphism associated with multiple sclerosis risk affects the EVI5 interactome. Hum Mol Genet. 2015 Dec 15; 24(24):7151-8. PMID: 26433934.
      View in: PubMed
    12. Moutsianas L, Jostins L, Beecham AH, Dilthey AT, Xifara DK, Ban M, Shah TS, Patsopoulos NA, Alfredsson L, Anderson CA, Attfield KE, Baranzini S, Barrett J, Binder TM, Booth D, Buck D, Celius EG, Cotsapas C, D'Alfonso S, Dendrou CA, Donnelly P, Dubois B, Fontaine B, Lar Fugger L, Goris A, Gourraud PA, Graetz C, Hemmer B, Hillert J, Kockum I, Leslie S, Lill CM, Martinelli-Boneschi F, Oksenberg JR, Olsson T, Oturai A, Saarela J, Søndergaard HB, Spurkland A, Taylor B, Winkelmann J, Zipp F, Haines JL, Pericak-Vance MA, Spencer CC, Stewart G, Hafler DA, Ivinson AJ, Harbo HF, Hauser SL, De Jager PL, Compston A, McCauley JL, Sawcer S, McVean G. Class II HLA interactions modulate genetic risk for multiple sclerosis. Nat Genet. 2015 Oct; 47(10):1107-13. PMID: 26343388; PMCID: PMC4874245.
      View in: PubMed, PubMed Central
    13. Wang L, Himmelstein DS, Santaniello A, Parvin M, Baranzini S. iCTNet2: integrating heterogeneous biological interactions to understand complex traits. F1000Res. 2015; 4:485. PMID: 26834985.
      View in: PubMed
    14. Khankhanian P, Matsushita T, Madireddy L, Lizée A, Din L, Moré JM, Gourraud PA, Hauser SL, Baranzini S, Oksenberg JR. Genetic contribution to multiple sclerosis risk among Ashkenazi Jews. BMC Med Genet. 2015; 16:55. PMID: 26212423; PMCID: PMC4557862.
      View in: PubMed, PubMed Central
    15. Himmelstein DS, Baranzini S. Heterogeneous Network Edge Prediction: A Data Integration Approach to Prioritize Disease-Associated Genes. PLoS Comput Biol. 2015 Jul; 11(7):e1004259. PMID: 26158728; PMCID: PMC4497619.
      View in: PubMed, PubMed Central
    16. Matsushita T, Madireddy L, Sprenger T, Khankhanian P, Magon S, Naegelin Y, Caverzasi E, Lindberg RL, Kappos L, Hauser SL, Oksenberg JR, Henry R, Pelletier D, Baranzini S. Genetic associations with brain cortical thickness in multiple sclerosis. Genes Brain Behav. 2015 Feb; 14(2):217-27. PMID: 25684059.
      View in: PubMed
    17. Harari D, Orr I, Rotkopf R, Baranzini S, Schreiber G. A robust type I interferon gene signature from blood RNA defines quantitative but not qualitative differences between three major IFNß drugs in the treatment of multiple sclerosis. Hum Mol Genet. 2015 Jun 1; 24(11):3192-205. PMID: 25721402.
      View in: PubMed
    18. Khankhanian P, Din L, Caillier SJ, Gourraud PA, Baranzini S. SNP imputation bias reduces effect size determination. Front Genet. 2015; 6:30. PMID: 25709616; PMCID: PMC4321633.
      View in: PubMed, PubMed Central
    19. Slavotinek AM, Garcia ST, Chandratillake G, Bardakjian T, Ullah E, Wu D, Umeda K, Lao R, Tang PL, Wan E, Madireddy L, Lyalina S, Mendelsohn BA, Dugan S, Tirch J, Tischler R, Harris J, Clark MJ, Chervitz S, Patwardhan A, West JM, Ursell P, de Alba Campomanes A, Schneider A, Kwok PY, Baranzini S, Chen RO. Exome sequencing in 32 patients with anophthalmia/microphthalmia and developmental eye defects. Clin Genet. 2015 Nov; 88(5):468-73. PMID: 25457163; PMCID: PMC4452457 [Available on 11/01/16].
      View in: PubMed, PubMed Central
    20. Wang L, Mousavi P, Baranzini S. iPINBPA: an integrative network-based functional module discovery tool for genome-wide association studies. Pac Symp Biocomput. 2015; 255-66. PMID: 25592586.
      View in: PubMed
    21. Nickles D, Madireddy L, Patel N, Isobe N, Miller BL, Baranzini S, Kramer JH, Oksenberg JR. Whole genome sequences of 2 octogenarians with sustained cognitive abilities. Neurobiol Aging. 2015 Mar; 36(3):1435-8. PMID: 25618617; PMCID: PMC4346472 [Available on 03/01/16].
      View in: PubMed, PubMed Central
    22. Haghikia A, Faissner S, Pappas D, Pula B, Akkad DA, Arning L, Ruhrmann S, Duscha A, Gold R, Baranzini S, Malhotra S, Montalban X, Comabella M, Chan A. Interferon-beta affects mitochondrial activity in CD4+ lymphocytes: Implications for mechanism of action in multiple sclerosis. Mult Scler. 2015 Sep; 21(10):1262-70. PMID: 25480861.
      View in: PubMed
    23. Baranzini S, Madireddy LR, Cromer A, D'Antonio M, Lehr L, Beelke M, Farmer P, Battaglini M, Caillier SJ, Stromillo ML, De Stefano N, Monnet E, Cree BA. Prognostic biomarkers of IFNb therapy in multiple sclerosis patients. Mult Scler. 2015 Jun; 21(7):894-904. PMID: 25392319.
      View in: PubMed
    24. Gustafsson M, Nestor CE, Zhang H, Barabási AL, Baranzini S, Brunak S, Chung KF, Federoff HJ, Gavin AC, Meehan RR, Picotti P, Pujana MÀ, Rajewsky N, Smith KG, Sterk PJ, Villoslada P, Benson M. Modules, networks and systems medicine for understanding disease and aiding diagnosis. Genome Med. 2014; 6(10):82. PMID: 25473422; PMCID: PMC4254417.
      View in: PubMed, PubMed Central
    25. Gourraud PA, Henry RG, Cree BA, Crane JC, Lizee A, Olson MP, Santaniello AV, Datta E, Zhu AH, Bevan CJ, Gelfand JM, Graves JS, Goodin DS, Green AJ, von Büdingen HC, Waubant E, Zamvil SS, Crabtree-Hartman E, Nelson S, Baranzini S, Hauser SL. Precision medicine in chronic disease management: The multiple sclerosis BioScreen. Ann Neurol. 2014 Nov; 76(5):633-42. PMID: 25263997; PMCID: PMC4214886.
      View in: PubMed, PubMed Central
    26. Wang L, Matsushita T, Madireddy L, Mousavi P, Baranzini S. PINBPA: cytoscape app for network analysis of GWAS data. Bioinformatics. 2015 Jan 15; 31(2):262-4. PMID: 25260698.
      View in: PubMed
    27. Baranzini S. The role of antiproliferative gene Tob1 in the immune system. Clin Exp Neuroimmunol. 2014 Jun 1; 5(2):132-136. PMID: 25071870.
      View in: PubMed
    28. Muñoz-Culla M, Irizar H, Castillo-Triviño T, Sáenz-Cuesta M, Sepúlveda L, Lopetegi I, de Munain AL, Olascoaga J, Baranzini S, Otaegui D. Blood miRNA expression pattern is a possible risk marker for natalizumab-associated progressive multifocal leukoencephalopathy in multiple sclerosis patients. Mult Scler. 2014 Dec; 20(14):1851-9. PMID: 24852919.
      View in: PubMed
    29. Molofsky AV, Kelley KW, Tsai HH, Redmond SA, Chang SM, Madireddy L, Chan JR, Baranzini S, Ullian EM, Rowitch DH. Astrocyte-encoded positional cues maintain sensorimotor circuit integrity. Nature. 2014 May 8; 509(7499):189-94. PMID: 24776795; PMCID: PMC4057936.
      View in: PubMed, PubMed Central
    30. Fancy SP, Harrington EP, Baranzini S, Silbereis JC, Shiow LR, Yuen TJ, Huang EJ, Lomvardas S, Rowitch DH. Parallel states of pathological Wnt signaling in neonatal brain injury and colon cancer. Nat Neurosci. 2014 Apr; 17(4):506-12. PMID: 24609463; PMCID: PMC3975168.
      View in: PubMed, PubMed Central
    31. Zastepa E, Fitz-Gerald L, Hallett M, Antel J, Bar-Or A, Baranzini S, Lapierre Y, Haegert DG. Naive CD4 T-cell activation identifies MS patients having rapid transition to progressive MS. Neurology. 2014 Feb 25; 82(8):681-90. PMID: 24453076; PMCID: PMC3945666.
      View in: PubMed, PubMed Central
    32. Damotte V, Guillot-Noel L, Patsopoulos NA, Madireddy L, El Behi M, De Jager PL, Baranzini S, Cournu-Rebeix I, Fontaine B. A gene pathway analysis highlights the role of cellular adhesion molecules in multiple sclerosis susceptibility. Genes Immun. 2014 Mar; 15(2):126-32. PMID: 24430173.
      View in: PubMed
    33. Parnell GP, Gatt PN, Krupa M, Nickles D, McKay FC, Schibeci SD, Batten M, Baranzini S, Henderson A, Barnett M, Slee M, Vucic S, Stewart GJ, Booth DR. The autoimmune disease-associated transcription factors EOMES and TBX21 are dysregulated in multiple sclerosis and define a molecular subtype of disease. Clin Immunol. 2014 Mar; 151(1):16-24. PMID: 24495857.
      View in: PubMed
    34. Baranzini S. Symposium 2-1  The autoimmunome: Similarities and differences among genetic susceptibility to common immune-related diseases. Nihon Rinsho Meneki Gakkai Kaishi. 2014; 37(4):261. PMID: 25297131.
      View in: PubMed
    35. Khankhanian P, Baranzini S, Johnson BA, Madireddy L, Nickles D, Croen LA, Wu YW. Sequencing of the IL6 gene in a case-control study of cerebral palsy in children. BMC Med Genet. 2013; 14:126. PMID: 24314052; PMCID: PMC3881497.
      View in: PubMed, PubMed Central
    36. Baranzini S. Gene expression profiling in MS: a fulfilled promise? Mult Scler. 2013 Dec; 19(14):1813-4. PMID: 24277731.
      View in: PubMed
    37. Beecham AH, Patsopoulos NA, Xifara DK, Davis MF, Kemppinen A, Cotsapas C, Shah TS, Spencer C, Booth D, Goris A, Oturai A, Saarela J, Fontaine B, Hemmer B, Martin C, Zipp F, D'Alfonso S, Martinelli-Boneschi F, Taylor B, Harbo HF, Kockum I, Hillert J, Olsson T, Ban M, Oksenberg JR, Hintzen R, Barcellos LF, Agliardi C, Alfredsson L, Alizadeh M, Anderson C, Andrews R, Søndergaard HB, Baker A, Band G, Baranzini S, Barizzone N, Barrett J, Bellenguez C, Bergamaschi L, Bernardinelli L, Berthele A, Biberacher V, Binder TM, Blackburn H, Bomfim IL, Brambilla P, Broadley S, Brochet B, Brundin L, Buck D, Butzkueven H, Caillier SJ, Camu W, Carpentier W, Cavalla P, Celius EG, Coman I, Comi G, Corrado L, Cosemans L, Cournu-Rebeix I, Cree BA, Cusi D, Damotte V, Defer G, Delgado SR, Deloukas P, di Sapio A, Dilthey AT, Donnelly P, Dubois B, Duddy M, Edkins S, Elovaara I, Esposito F, Evangelou N, Fiddes B, Field J, Franke A, Freeman C, Frohlich IY, Galimberti D, Gieger C, Gourraud PA, Graetz C, Graham A, Grummel V, Guaschino C, Hadjixenofontos A, Hakonarson H, Halfpenny C, Hall G, Hall P, Hamsten A, Harley J, Harrower T, Hawkins C, Hellenthal G, Hillier C, Hobart J, Hoshi M, Hunt SE, Jagodic M, Jelcic I, Jochim A, Kendall B, Kermode A, Kilpatrick T, Koivisto K, Konidari I, Korn T, Kronsbein H, Langford C, Larsson M, Lathrop M, Lebrun-Frenay C, Lechner-Scott J, Lee MH, Leone MA, Leppä V, Liberatore G, Lie BA, Lill CM, Lindén M, Link J, Luessi F, Lycke J, Macciardi F, Männistö S, Manrique CP, Martin R, Martinelli V, Mason D, Mazibrada G, McCabe C, Mero IL, Mescheriakova J, Moutsianas L, Myhr KM, Nagels G, Nicholas R, Nilsson P, Piehl F, Pirinen M, Price SE, Quach H, Reunanen M, Robberecht W, Robertson NP, Rodegher M, Rog D, Salvetti M, Schnetz-Boutaud NC, Sellebjerg F, Selter RC, Schaefer C, Shaunak S, Shen L, Shields S, Siffrin V, Slee M, Sorensen PS, Sorosina M, Sospedra M, Spurkland A, Strange A, Sundqvist E, Thijs V, Thorpe J, Ticca A, Tienari P, van Duijn C, Visser EM, Vucic S, Westerlind H, Wiley JS, Wilkins A, Wilson JF, Winkelmann J, Zajicek J, Zindler E, Haines JL, Pericak-Vance MA, Ivinson AJ, Stewart G, Hafler D, Hauser SL, Compston A, McVean G, De Jager P, Sawcer SJ, McCauley JL. Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. Nat Genet. 2013 Nov; 45(11):1353-60. PMID: 24076602; PMCID: PMC3832895.
      View in: PubMed, PubMed Central
    38. Molofsky AV, Glasgow SM, Chaboub LS, Tsai HH, Murnen AT, Kelley KW, Fancy SP, Yuen TJ, Madireddy L, Baranzini S, Deneen B, Rowitch DH, Oldham MC. Expression profiling of Aldh1l1-precursors in the developing spinal cord reveals glial lineage-specific genes and direct Sox9-Nfe2l1 interactions. Glia. 2013 Sep; 61(9):1518-32. PMID: 23840004; PMCID: PMC3909648.
      View in: PubMed, PubMed Central
    39. Schulze-Topphoff U, Casazza S, Varrin-Doyer M, Pekarek K, Sobel RA, Hauser SL, Oksenberg JR, Zamvil SS, Baranzini S. Tob1 plays a critical role in the activation of encephalitogenic T cells in CNS autoimmunity. J Exp Med. 2013 Jul 1; 210(7):1301-9. PMID: 23797093; PMCID: PMC3698524.
      View in: PubMed, PubMed Central
    40. Rossi S, Studer V, Moscatelli A, Motta C, Coghe G, Fenu G, Caillier S, Buttari F, Mori F, Barbieri F, Castelli M, De Chiara V, Monteleone F, Mancino R, Bernardi G, Baranzini S, Marrosu MG, Oksenberg JR, Centonze D. Opposite roles of NMDA receptors in relapsing and primary progressive multiple sclerosis. PLoS One. 2013; 8(6):e67357. PMID: 23840674; PMCID: PMC3696106.
      View in: PubMed, PubMed Central
    41. Nickles D, Chen HP, Li MM, Khankhanian P, Madireddy L, Caillier SJ, Santaniello A, Cree BA, Pelletier D, Hauser SL, Oksenberg JR, Baranzini S. Blood RNA profiling in a large cohort of multiple sclerosis patients and healthy controls. Hum Mol Genet. 2013 Oct 15; 22(20):4194-205. PMID: 23748426; PMCID: PMC3781642.
      View in: PubMed, PubMed Central
    42. Network-based multiple sclerosis pathway analysis with GWAS data from 15,000 cases and 30,000 controls. Am J Hum Genet. 2013 Jun 6; 92(6):854-65. PMID: 23731539; PMCID: PMC3958952.
      View in: PubMed, PubMed Central
    43. Dutta R, Chomyk AM, Chang A, Ribaudo MV, Deckard SA, Doud MK, Edberg DD, Bai B, Li M, Baranzini S, Fox RJ, Staugaitis SM, Macklin WB, Trapp BD. Hippocampal demyelination and memory dysfunction are associated with increased levels of the neuronal microRNA miR-124 and reduced AMPA receptors. Ann Neurol. 2013 May; 73(5):637-45. PMID: 23595422; PMCID: PMC3679350.
      View in: PubMed, PubMed Central
    44. Gourraud PA, Sdika M, Khankhanian P, Henry RG, Beheshtian A, Matthews PM, Hauser SL, Oksenberg JR, Pelletier D, Baranzini S. A genome-wide association study of brain lesion distribution in multiple sclerosis. Brain. 2013 Apr; 136(Pt 4):1012-24. PMID: 23412934; PMCID: PMC3613709.
      View in: PubMed, PubMed Central
    45. Pappas DJ, Gabatto PA, Oksenberg D, Khankhanian P, Baranzini S, Gan L, Oksenberg JR. Transcriptional expression patterns triggered by chemically distinct neuroprotective molecules. Neuroscience. 2012 Dec 13; 226:10-20. PMID: 22986168; PMCID: PMC3489981.
      View in: PubMed, PubMed Central
    46. Nickles D, Madireddy L, Yang S, Khankhanian P, Lincoln S, Hauser SL, Oksenberg JR, Baranzini S. In depth comparison of an individual's DNA and its lymphoblastoid cell line using whole genome sequencing. BMC Genomics. 2012; 13:477. PMID: 22974163; PMCID: PMC3473256.
      View in: PubMed, PubMed Central
    47. Gourraud PA, Harbo HF, Hauser SL, Baranzini S. The genetics of multiple sclerosis: an up-to-date review. Immunol Rev. 2012 Jul; 248(1):87-103. PMID: 22725956.
      View in: PubMed
    48. Han MH, Lundgren DH, Jaiswal S, Chao M, Graham KL, Garris CS, Axtell RC, Ho PP, Lock CB, Woodard JI, Brownell SE, Zoudilova M, Hunt JF, Baranzini S, Butcher EC, Raine CS, Sobel RA, Han DK, Weissman I, Steinman L. Janus-like opposing roles of CD47 in autoimmune brain inflammation in humans and mice. J Exp Med. 2012 Jul 2; 209(7):1325-34. PMID: 22734047; PMCID: PMC3405500.
      View in: PubMed, PubMed Central
    49. Su SY, Kasberger J, Baranzini S, Byerley W, Liao W, Oksenberg J, Sherr E, Jorgenson E. Detection of identity by descent using next-generation whole genome sequencing data. BMC Bioinformatics. 2012; 13:121. PMID: 22672699; PMCID: PMC3403908.
      View in: PubMed, PubMed Central
    50. Baranzini S, Nickles D. Genetics of multiple sclerosis: swimming in an ocean of data. Curr Opin Neurol. 2012 Jun; 25(3):239-45. PMID: 22516854.
      View in: PubMed
    51. Villoslada P, Baranzini S. Data integration and systems biology approaches for biomarker discovery: challenges and opportunities for multiple sclerosis. J Neuroimmunol. 2012 Jul 15; 248(1-2):58-65. PMID: 22281286.
      View in: PubMed
    52. Wang L, Khankhanian P, Baranzini S, Mousavi P. iCTNet: a Cytoscape plugin to produce and analyze integrative complex traits networks. BMC Bioinformatics. 2011; 12:380. PMID: 21943367; PMCID: PMC3190406.
      View in: PubMed, PubMed Central
    53. Sawcer S, Hellenthal G, Pirinen M, Spencer CC, Patsopoulos NA, Moutsianas L, Dilthey A, Su Z, Freeman C, Hunt SE, Edkins S, Gray E, Booth DR, Potter SC, Goris A, Band G, Oturai AB, Strange A, Saarela J, Bellenguez C, Fontaine B, Gillman M, Hemmer B, Gwilliam R, Zipp F, Jayakumar A, Martin R, Leslie S, Hawkins S, Giannoulatou E, D'alfonso S, Blackburn H, Martinelli Boneschi F, Liddle J, Harbo HF, Perez ML, Spurkland A, Waller MJ, Mycko MP, Ricketts M, Comabella M, Hammond N, Kockum I, McCann OT, Ban M, Whittaker P, Kemppinen A, Weston P, Hawkins C, Widaa S, Zajicek J, Dronov S, Robertson N, Bumpstead SJ, Barcellos LF, Ravindrarajah R, Abraham R, Alfredsson L, Ardlie K, Aubin C, Baker A, Baker K, Baranzini S, Bergamaschi L, Bergamaschi R, Bernstein A, Berthele A, Boggild M, Bradfield JP, Brassat D, Broadley SA, Buck D, Butzkueven H, Capra R, Carroll WM, Cavalla P, Celius EG, Cepok S, Chiavacci R, Clerget-Darpoux F, Clysters K, Comi G, Cossburn M, Cournu-Rebeix I, Cox MB, Cozen W, Cree BA, Cross AH, Cusi D, Daly MJ, Davis E, de Bakker PI, Debouverie M, D'hooghe MB, Dixon K, Dobosi R, Dubois B, Ellinghaus D, Elovaara I, Esposito F, Fontenille C, Foote S, Franke A, Galimberti D, Ghezzi A, Glessner J, Gomez R, Gout O, Graham C, Grant SF, Guerini FR, Hakonarson H, Hall P, Hamsten A, Hartung HP, Heard RN, Heath S, Hobart J, Hoshi M, Infante-Duarte C, Ingram G, Ingram W, Islam T, Jagodic M, Kabesch M, Kermode AG, Kilpatrick TJ, Kim C, Klopp N, Koivisto K, Larsson M, Lathrop M, Lechner-Scott JS, Leone MA, Leppä V, Liljedahl U, Bomfim IL, Lincoln RR, Link J, Liu J, Lorentzen AR, Lupoli S, Macciardi F, Mack T, Marriott M, Martinelli V, Mason D, McCauley JL, Mentch F, Mero IL, Mihalova T, Montalban X, Mottershead J, Myhr KM, Naldi P, Ollier W, Page A, Palotie A, Pelletier J, Piccio L, Pickersgill T, Piehl F, Pobywajlo S, Quach HL, Ramsay PP, Reunanen M, Reynolds R, Rioux JD, Rodegher M, Roesner S, Rubio JP, Rückert IM, Salvetti M, Salvi E, Santaniello A, Schaefer CA, Schreiber S, Schulze C, Scott RJ, Sellebjerg F, Selmaj KW, Sexton D, Shen L, Simms-Acuna B, Skidmore S, Sleiman PM, Smestad C, Sørensen PS, Søndergaard HB, Stankovich J, Strange RC, Sulonen AM, Sundqvist E, Syvänen AC, Taddeo F, Taylor B, Blackwell JM, Tienari P, Bramon E, Tourbah A, Brown MA, Tronczynska E, Casas JP, Tubridy N, Corvin A, Vickery J, Jankowski J, Villoslada P, Markus HS, Wang K, Mathew CG, Wason J, Palmer CN, Wichmann HE, Plomin R, Willoughby E, Rautanen A, Winkelmann J, Wittig M, Trembath RC, Yaouanq J, Viswanathan AC, Zhang H, Wood NW, Zuvich R, Deloukas P, Langford C, Duncanson A, Oksenberg JR, Pericak-Vance MA, Haines JL, Olsson T, Hillert J, Ivinson AJ, De Jager PL, Peltonen L, Stewart GJ, Hafler DA, Hauser SL, McVean G, Donnelly P, Compston A. Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature. 2011 Aug 11; 476(7359):214-9. PMID: 21833088; PMCID: PMC3182531.
      View in: PubMed, PubMed Central
    54. Fancy SP, Harrington EP, Yuen TJ, Silbereis JC, Zhao C, Baranzini S, Bruce CC, Otero JJ, Huang EJ, Nusse R, Franklin RJ, Rowitch DH. Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination. Nat Neurosci. 2011 Aug; 14(8):1009-16. PMID: 21706018; PMCID: PMC3145042.
      View in: PubMed, PubMed Central
    55. Haghikia A, Perrech M, Pula B, Ruhrmann S, Potthoff A, Brockmeyer NH, Goelz S, Wiendl H, Lindå H, Ziemssen T, Baranzini S, Käll TB, Bengel D, Olsson T, Gold R, Chan A. Functional energetics of CD4+-cellular immunity in monoclonal antibody-associated progressive multifocal leukoencephalopathy in autoimmune disorders. PLoS One. 2011; 6(4):e18506. PMID: 21533133; PMCID: PMC3080364.
      View in: PubMed, PubMed Central
    56. Slavotinek AM, Baranzini S, Schanze D, Labelle-Dumais C, Short KM, Chao R, Yahyavi M, Bijlsma EK, Chu C, Musone S, Wheatley A, Kwok PY, Marles S, Fryns JP, Maga AM, Hassan MG, Gould DB, Madireddy L, Li C, Cox TC, Smyth I, Chudley AE, Zenker M. Manitoba-oculo-tricho-anal (MOTA) syndrome is caused by mutations in FREM1. J Med Genet. 2011 Jun; 48(6):375-82. PMID: 21507892; PMCID: PMC4294942.
      View in: PubMed, PubMed Central
    57. Wang JH, Pappas D, De Jager PL, Pelletier D, de Bakker PI, Kappos L, Polman CH, Chibnik LB, Hafler DA, Matthews PM, Hauser SL, Baranzini S, Oksenberg JR. Modeling the cumulative genetic risk for multiple sclerosis from genome-wide association data. Genome Med. 2011; 3(1):3. PMID: 21244703; PMCID: PMC3092088.
      View in: PubMed, PubMed Central
    58. Baranzini S. Revealing the genetic basis of multiple sclerosis: are we there yet? Curr Opin Genet Dev. 2011 Jun; 21(3):317-24. PMID: 21247752; PMCID: PMC3105160.
      View in: PubMed, PubMed Central
    59. Sorani MD, Manley GT, Claude Hemphill J, Baranzini S. Dynamic, multi-level network models of clinical trials. Pac Symp Biocomput. 2011; 38-49. PMID: 21121031.
      View in: PubMed
    60. Fancy SP, Chan JR, Baranzini S, Franklin RJ, Rowitch DH. Myelin regeneration: a recapitulation of development? Annu Rev Neurosci. 2011; 34:21-43. PMID: 21692657.
      View in: PubMed
    61. Khankhanian P, Gourraud PA, Caillier SJ, Santaniello A, Hauser SL, Baranzini S, Oksenberg JR. Genetic variation in the odorant receptors family 13 and the mhc loci influence mate selection in a multiple sclerosis dataset. BMC Genomics. 2010; 11:626. PMID: 21067613; PMCID: PMC3091764.
      View in: PubMed, PubMed Central
    62. Baranzini S, Srinivasan R, Khankhanian P, Okuda DT, Nelson SJ, Matthews PM, Hauser SL, Oksenberg JR, Pelletier D. Genetic variation influences glutamate concentrations in brains of patients with multiple sclerosis. Brain. 2010 Sep; 133(9):2603-11. PMID: 20802204; PMCID: PMC2929334.
      View in: PubMed, PubMed Central
    63. Oksenberg JR, Baranzini S. Multiple sclerosis genetics--is the glass half full, or half empty? Nat Rev Neurol. 2010 Aug; 6(8):429-37. PMID: 20625377.
      View in: PubMed
    64. Baranzini S, Mudge J, van Velkinburgh JC, Khankhanian P, Khrebtukova I, Miller NA, Zhang L, Farmer AD, Bell CJ, Kim RW, May GD, Woodward JE, Caillier SJ, McElroy JP, Gomez R, Pando MJ, Clendenen LE, Ganusova EE, Schilkey FD, Ramaraj T, Khan OA, Huntley JJ, Luo S, Kwok PY, Wu TD, Schroth GP, Oksenberg JR, Hauser SL, Kingsmore SF. Genome, epigenome and RNA sequences of monozygotic twins discordant for multiple sclerosis. Nature. 2010 Apr 29; 464(7293):1351-6. PMID: 20428171; PMCID: PMC2862593.
      View in: PubMed, PubMed Central
    65. Baranzini S. The genetics of autoimmune diseases: a networked perspective. Curr Opin Immunol. 2009 Dec; 21(6):596-605. PMID: 19896815.
      View in: PubMed
    66. Otaegui D, Baranzini S, Armañanzas R, Calvo B, Muñoz-Culla M, Khankhanian P, Inza I, Lozano JA, Castillo-Triviño T, Asensio A, Olaskoaga J, López de Munain A. Differential micro RNA expression in PBMC from multiple sclerosis patients. PLoS One. 2009; 4(7):e6309. PMID: 19617918; PMCID: PMC2708922.
      View in: PubMed, PubMed Central
    67. Pappas DJ, Coppola G, Gabatto PA, Gao F, Geschwind DH, Oksenberg JR, Baranzini S. Longitudinal system-based analysis of transcriptional responses to type I interferons. Physiol Genomics. 2009 Aug 7; 38(3):362-71. PMID: 19531577.
      View in: PubMed
    68. De Jager PL, Jia X, Wang J, de Bakker PI, Ottoboni L, Aggarwal NT, Piccio L, Raychaudhuri S, Tran D, Aubin C, Briskin R, Romano S, Baranzini S, McCauley JL, Pericak-Vance MA, Haines JL, Gibson RA, Naeglin Y, Uitdehaag B, Matthews PM, Kappos L, Polman C, McArdle WL, Strachan DP, Evans D, Cross AH, Daly MJ, Compston A, Sawcer SJ, Weiner HL, Hauser SL, Hafler DA, Oksenberg JR. Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. Nat Genet. 2009 Jul; 41(7):776-82. PMID: 19525953; PMCID: PMC2757648.
      View in: PubMed, PubMed Central
    69. Fancy SP, Baranzini S, Zhao C, Yuk DI, Irvine KA, Kaing S, Sanai N, Franklin RJ, Rowitch DH. Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS. Genes Dev. 2009 Jul 1; 23(13):1571-85. PMID: 19515974; PMCID: PMC2704469.
      View in: PubMed, PubMed Central
    70. Baranzini S, Galwey NW, Wang J, Khankhanian P, Lindberg R, Pelletier D, Wu W, Uitdehaag BM, Kappos L, Polman CH, Matthews PM, Hauser SL, Gibson RA, Oksenberg JR, Barnes MR. Pathway and network-based analysis of genome-wide association studies in multiple sclerosis. Hum Mol Genet. 2009 Jun 1; 18(11):2078-90. PMID: 19286671; PMCID: PMC2678928.
      View in: PubMed, PubMed Central
    71. Villoslada P, Steinman L, Baranzini S. Systems biology and its application to the understanding of neurological diseases. Ann Neurol. 2009 Feb; 65(2):124-39. PMID: 19260029.
      View in: PubMed
    72. Okuda DT, Mowry EM, Beheshtian A, Waubant E, Baranzini S, Goodin DS, Hauser SL, Pelletier D. Incidental MRI anomalies suggestive of multiple sclerosis: the radiologically isolated syndrome. Neurology. 2009 Mar 3; 72(9):800-5. PMID: 19073949.
      View in: PubMed
    73. Okuda DT, Srinivasan R, Oksenberg JR, Goodin DS, Baranzini S, Beheshtian A, Waubant E, Zamvil SS, Leppert D, Qualley P, Lincoln R, Gomez R, Caillier S, George M, Wang J, Nelson SJ, Cree BA, Hauser SL, Pelletier D. Genotype-Phenotype correlations in multiple sclerosis: HLA genes influence disease severity inferred by 1HMR spectroscopy and MRI measures. Brain. 2009 Jan; 132(Pt 1):250-9. PMID: 19022862; PMCID: PMC2638695.
      View in: PubMed, PubMed Central
    74. Baranzini S, Wang J, Gibson RA, Galwey N, Naegelin Y, Barkhof F, Radue EW, Lindberg RL, Uitdehaag BM, Johnson MR, Angelakopoulou A, Hall L, Richardson JC, Prinjha RK, Gass A, Geurts JJ, Kragt J, Sombekke M, Vrenken H, Qualley P, Lincoln RR, Gomez R, Caillier SJ, George MF, Mousavi H, Guerrero R, Okuda DT, Cree BA, Green AJ, Waubant E, Goodin DS, Pelletier D, Matthews PM, Hauser SL, Kappos L, Polman CH, Oksenberg JR. Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. Hum Mol Genet. 2009 Feb 15; 18(4):767-78. PMID: 19010793; PMCID: PMC4334814.
      View in: PubMed, PubMed Central
    75. Comabella M, Río J, Espejo C, Ruiz de Villa M, Al-Zayat H, Nos C, Deisenhammer F, Baranzini S, Nonell L, López C, Julià E, Oksenberg JR, Montalban X. Changes in matrix metalloproteinases and their inhibitors during interferon-beta treatment in multiple sclerosis. Clin Immunol. 2009 Feb; 130(2):145-50. PMID: 18945642.
      View in: PubMed
    76. Caillier SJ, Briggs F, Cree BA, Baranzini S, Fernandez-Viña M, Ramsay PP, Khan O, Royal W, Hauser SL, Barcellos LF, Oksenberg JR. Uncoupling the roles of HLA-DRB1 and HLA-DRB5 genes in multiple sclerosis. J Immunol. 2008 Oct 15; 181(8):5473-80. PMID: 18832704; PMCID: PMC4346327.
      View in: PubMed, PubMed Central
    77. Corvol JC, Pelletier D, Henry RG, Caillier SJ, Wang J, Pappas D, Casazza S, Okuda DT, Hauser SL, Oksenberg JR, Baranzini S. Abrogation of T cell quiescence characterizes patients at high risk for multiple sclerosis after the initial neurological event. Proc Natl Acad Sci U S A. 2008 Aug 19; 105(33):11839-44. PMID: 18689680; PMCID: PMC2504481.
      View in: PubMed, PubMed Central
    78. Oksenberg JR, Baranzini S, Sawcer S, Hauser SL. The genetics of multiple sclerosis: SNPs to pathways to pathogenesis. Nat Rev Genet. 2008 Jul; 9(7):516-26. PMID: 18542080.
      View in: PubMed
    79. Hunt CA, Baranzini S, Matthay MA, Park S. A framework and mechanistically focused, in silico method for enabling rational translational research. Summit on Translat Bioinforma. 2008; 2008:46-50. PMID: 21347126; PMCID: PMC3041517.
      View in: PubMed, PubMed Central
    80. Han MH, Hwang SI, Roy DB, Lundgren DH, Price JV, Ousman SS, Fernald GH, Gerlitz B, Robinson WH, Baranzini S, Grinnell BW, Raine CS, Sobel RA, Han DK, Steinman L. Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets. Nature. 2008 Feb 28; 451(7182):1076-81. PMID: 18278032.
      View in: PubMed
    81. Goertsches R, Baranzini S, Morcillo C, Nos C, Camiña M, Oksenberg JR, Montalban X, Comabella M. Evidence for association of chromosome 10 open reading frame (C10orf27) gene polymorphisms and multiple sclerosis. Mult Scler. 2008 Apr; 14(3):412-4. PMID: 18208870.
      View in: PubMed
    82. Byun E, Caillier SJ, Montalban X, Villoslada P, Fernández O, Brassat D, Comabella M, Wang J, Barcellos LF, Baranzini S, Oksenberg JR. Genome-wide pharmacogenomic analysis of the response to interferon beta therapy in multiple sclerosis. Arch Neurol. 2008 Mar; 65(3):337-44. PMID: 18195134.
      View in: PubMed
    83. Otaegui D, Mostafavi S, Bernard CC, Lopez de Munain A, Mousavi P, Oksenberg JR, Baranzini S. Increased transcriptional activity of milk-related genes following the active phase of experimental autoimmune encephalomyelitis and multiple sclerosis. J Immunol. 2007 Sep 15; 179(6):4074-82. PMID: 17785846.
      View in: PubMed
    84. Sriram U, Wong M, Caillier SJ, Hecht FM, Elkins MK, Levy JA, Oksenberg JR, Baranzini S. Quantitative longitudinal analysis of T cell receptor repertoire expression in HIV-infected patients on antiretroviral and interleukin-2 therapy. AIDS Res Hum Retroviruses. 2007 May; 23(5):741-7. PMID: 17531001.
      View in: PubMed
    85. Fernald GH, Knott S, Pachner A, Caillier SJ, Narayan K, Oksenberg JR, Mousavi P, Baranzini S. Genome-wide network analysis reveals the global properties of IFN-beta immediate transcriptional effects in humans. J Immunol. 2007 Apr 15; 178(8):5076-85. PMID: 17404290.
      View in: PubMed
    86. Pedemonte E, Benvenuto F, Casazza S, Mancardi G, Oksenberg JR, Uccelli A, Baranzini S. The molecular signature of therapeutic mesenchymal stem cells exposes the architecture of the hematopoietic stem cell niche synapse. BMC Genomics. 2007; 8:65. PMID: 17341312; PMCID: PMC1821333.
      View in: PubMed, PubMed Central
    87. Dunn SE, Ousman SS, Sobel RA, Zuniga L, Baranzini S, Youssef S, Crowell A, Loh J, Oksenberg J, Steinman L. Peroxisome proliferator-activated receptor (PPAR)alpha expression in T cells mediates gender differences in development of T cell-mediated autoimmunity. J Exp Med. 2007 Feb 19; 204(2):321-30. PMID: 17261635; PMCID: PMC2118721.
      View in: PubMed, PubMed Central
    88. Baranzini S. Systems-based medicine approaches to understand and treat complex diseases. The example of multiple sclerosis. Autoimmunity. 2006 Dec; 39(8):651-62. PMID: 17178562.
      View in: PubMed
    89. Barcellos LF, Sawcer S, Ramsay PP, Baranzini S, Thomson G, Briggs F, Cree BC, Begovich AB, Villoslada P, Montalban X, Uccelli A, Savettieri G, Lincoln RR, DeLoa C, Haines JL, Pericak-Vance MA, Compston A, Hauser SL, Oksenberg JR. Heterogeneity at the HLA-DRB1 locus and risk for multiple sclerosis. Hum Mol Genet. 2006 Sep 15; 15(18):2813-24. PMID: 16905561.
      View in: PubMed
    90. Mostafavi S, Baranzini S, Oksernberg J, Mousavi P. Predictive modeling of therapy response in multiple sclerosis using gene expression data. Conf Proc IEEE Eng Med Biol Soc. 2006; 1:5519-22. PMID: 17946311.
      View in: PubMed
    91. Fernald GH, Yeh RF, Hauser SL, Oksenberg JR, Baranzini S. Mapping gene activity in complex disorders: Integration of expression and genomic scans for multiple sclerosis. J Neuroimmunol. 2005 Oct; 167(1-2):157-69. PMID: 16129498.
      View in: PubMed
    92. Baranzini S, Bernard CC, Oksenberg JR. Modular transcriptional activity characterizes the initiation and progression of autoimmune encephalomyelitis. J Immunol. 2005 Jun 1; 174(11):7412-22. PMID: 15905590.
      View in: PubMed
    93. Baranzini S, Oksenberg JR. Genomics and new targets for multiple sclerosis. Pharmacogenomics. 2005 Mar; 6(2):151-61. PMID: 15882133.
      View in: PubMed
    94. Elkins MK, Vittinghoff E, Baranzini S, Hecht FM, Sriram U, Busch MP, Levy JA, Oksenberg JR. Longitudinal analysis of B cell repertoire and antibody gene rearrangements during early HIV infection. Genes Immun. 2005 Feb; 6(1):66-9. PMID: 15538390.
      View in: PubMed
    95. Baranzini S, Mousavi P, Rio J, Caillier SJ, Stillman A, Villoslada P, Wyatt MM, Comabella M, Greller LD, Somogyi R, Montalban X, Oksenberg JR. Transcription-based prediction of response to IFNbeta using supervised computational methods. PLoS Biol. 2005 Jan; 3(1):e2. PMID: 15630474; PMCID: PMC539058.
      View in: PubMed, PubMed Central
    96. Baranzini S. Gene expression profiling in neurological disorders: toward a systems-level understanding of the brain. Neuromolecular Med. 2004; 6(1):31-51. PMID: 15781975.
      View in: PubMed
    97. Oksenberg JR, Barcellos LF, Cree BA, Baranzini S, Bugawan TL, Khan O, Lincoln RR, Swerdlin A, Mignot E, Lin L, Goodin D, Erlich HA, Schmidt S, Thomson G, Reich DE, Pericak-Vance MA, Haines JL, Hauser SL. Mapping multiple sclerosis susceptibility to the HLA-DR locus in African Americans. Am J Hum Genet. 2004 Jan; 74(1):160-7. PMID: 14669136; PMCID: PMC1181903.
      View in: PubMed, PubMed Central
    98. Huuskonen J, Abedin M, Vishnu M, Pullinger CR, Baranzini S, Kane JP, Fielding PE, Fielding CJ. Dynamic regulation of alternative ATP-binding cassette transporter A1 transcripts. Biochem Biophys Res Commun. 2003 Jun 27; 306(2):463-8. PMID: 12804586.
      View in: PubMed
    99. Caillier S, Barcellos LF, Baranzini S, Swerdlin A, Lincoln RR, Steinman L, Martin E, Haines JL, Pericak-Vance M, Hauser SL, Oksenberg JR. Osteopontin polymorphisms and disease course in multiple sclerosis. Genes Immun. 2003 Jun; 4(4):312-5. PMID: 12761568.
      View in: PubMed
    100. Giliberto F, Ferreiro V, Dalamón V, Surace E, Cotignola J, Esperante S, Borelina D, Baranzini S, Szijan I. Direct deletion analysis in two Duchenne muscular dystrophy symptomatic females using polymorphic dinucleotide (CA)n loci within the dystrophin gene. J Biochem Mol Biol. 2003 Mar 31; 36(2):179-84. PMID: 12689516.
      View in: PubMed
    101. Sriram U, Barcellos LF, Villoslada P, Rio J, Baranzini S, Caillier S, Stillman A, Hauser SL, Montalban X, Oksenberg JR. Pharmacogenomic analysis of interferon receptor polymorphisms in multiple sclerosis. Genes Immun. 2003 Mar; 4(2):147-52. PMID: 12618863.
      View in: PubMed
    102. Baranzini S, Hauser SL. Large-scale gene-expression studies and the challenge of multiple sclerosis. Genome Biol. 2002 Sep 16; 3(10):reviews1027. PMID: 12372148; PMCID: PMC244911.
      View in: PubMed, PubMed Central
    103. Villoslada P, Barcellos LF, Rio J, Begovich AB, Tintore M, Sastre-Garriga J, Baranzini S, Casquero P, Hauser SL, Montalban X, Oksenberg JR. The HLA locus and multiple sclerosis in Spain. Role in disease susceptibility, clinical course and response to interferon-beta. J Neuroimmunol. 2002 Sep; 130(1-2):194-201. PMID: 12225902.
      View in: PubMed
    104. Baranzini S, Laxer K, Bollen A, Oksenberg JR. Gene expression analysis reveals altered brain transcription of glutamate receptors and inflammatory genes in a patient with chronic focal (Rasmussen's) encephalitis. J Neuroimmunol. 2002 Jul; 128(1-2):9-15. PMID: 12098505.
      View in: PubMed
    105. Baranzini S, Laxer K, Saketkhoo R, Elkins MK, Parent JM, Mantegazza R, Oksenberg JR. Analysis of antibody gene rearrangement, usage, and specificity in chronic focal encephalitis. Neurology. 2002 Mar 12; 58(5):709-16. PMID: 11889232.
      View in: PubMed
    106. Baranzini S, Oksenberg JR, Hauser SL. New insights into the genetics of multiple sclerosis. J Rehabil Res Dev. 2002 Mar-Apr; 39(2):201-9. PMID: 12051464.
      View in: PubMed
    107. Chabas D, Baranzini S, Mitchell D, Bernard CC, Rittling SR, Denhardt DT, Sobel RA, Lock C, Karpuj M, Pedotti R, Heller R, Oksenberg JR, Steinman L. The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease. Science. 2001 Nov 23; 294(5547):1731-5. PMID: 11721059.
      View in: PubMed
    108. Oksenberg JR, Baranzini S, Barcellos LF, Hauser SL. Multiple sclerosis: genomic rewards. J Neuroimmunol. 2001 Feb 15; 113(2):171-84. PMID: 11164900.
      View in: PubMed
    109. Baranzini S, Elfstrom C, Chang SY, Butunoi C, Murray R, Higuchi R, Oksenberg JR. Transcriptional analysis of multiple sclerosis brain lesions reveals a complex pattern of cytokine expression. J Immunol. 2000 Dec 1; 165(11):6576-82. PMID: 11086101.
      View in: PubMed
    110. Baranzini S, Jeong MC, Butunoi C, Murray RS, Bernard CC, Oksenberg JR. B cell repertoire diversity and clonal expansion in multiple sclerosis brain lesions. J Immunol. 1999 Nov 1; 163(9):5133-44. PMID: 10528220.
      View in: PubMed
    111. Baranzini S, Giliberto F, Dalamon V, Barreiro C, García-Erro M, Grippo J, Szijan I. Carrier detection in Duchenne and Becker muscular dystrophy Argentine families. Clin Genet. 1998 Dec; 54(6):503-11. PMID: 9894797.
      View in: PubMed
    112. Baranzini S, Giliberto F, Herrera M, Bernath V, Barreiro C, Garcia Erro M, Grippo J, Szijan I. Deletion patterns in Argentine patients with Duchenne and Becker muscular dystrophy. Neurol Res. 1998 Jul; 20(5):409-414. PMID: 9664586.
      View in: PubMed
    113. Arbetman A, Abdala M, Fandiño A, Herrera J, Baranzini S, Borelina D, Parma D, Manzitti J, Barreiro C, Giliberto F, Szijan I. Clinical, cytogenetic, and molecular testing of Argentine patients with retinoblastoma. J AAPOS. 1998 Apr; 2(2):102-7. PMID: 10530971.
      View in: PubMed
    114. Baranzini S, Lenk U, Szijan I, Speer A. Four new polymorphisms in the human dystrophin gene from an Argentinian population. Muscle Nerve. 1997 Nov; 20(11):1451-3. PMID: 9342163.
      View in: PubMed
    115. Baranzini S, del Rey G, Nigro N, Szijan I, Chamoles N, Cresto JC. Patient with an Xp21 contiguous gene deletion syndrome in association with agenesis of the corpus callosum. Am J Med Genet. 1997 Jun 13; 70(3):216-21. PMID: 9188656.
      View in: PubMed
    116. di Fulvio M, Chiesa AE, Baranzini S, Gruñiero-Papendieck L, Masini-Repiso AM, Targovnik HM. A new point mutation (M313T) in the thyroid hormone receptor beta gene in a patient with resistance to thyroid hormone. Thyroid. 1997 Feb; 7(1):43-4. PMID: 9086569.
      View in: PubMed
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