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Deborah French, PhD

Title(s)Associate Professor, Laboratory Medicine
SchoolSchool of Medicine
Address185 Berry Street Bldg B
San Francisco CA 94158
Phone415-514-6627
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    Collapse Biography 
    Collapse Education and Training
    University of StrathclydeB.Sc.Biochemistry
    University of StrathclydePh.D.Biochemistry
    St Jude Children's Research HospitalPostdoctoral StudiesPharmaceutical Sciences
    University of California, San FranciscoPostdoctoral StudiesGraduate Division

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Side-effects of COVID-19 on patient care: An INR story. J Appl Lab Med. 2021 Mar 24. Pearson LN, Johnson SA, Greene DN, Chambliss AB, Farnsworth CW, French D, Herman DS, Kavsak PA, Merril AE, Lo SM, Lyon ME, SoRelle JA, Schmidt RL. PMID: 33760097.
      View in: PubMed   Mentions:    Fields:    
    2. RUNX1 haploinsufficiency causes a marked deficiency of megakaryocyte-biased hematopoietic progenitor cells. Blood. 2021 Feb 09. Estevez B, Borst S, Jarocha DJ, Sudunagunta VS, Gonzalez M, Garifallou J, Hakonarson H, Gao P, Tan K, Liu PP, Bagga S, Holdreith N, Tong W, Speck NA, French DL, Gadue P, Poncz M. PMID: 33569577.
      View in: PubMed   Mentions:    Fields:    
    3. Generation of a double insulin and somatostatin reporter line, SCSe001-A-3, for the advancement of stem cell-derived pancreatic islets. Stem Cell Res. 2020 Dec 08; 50:102112. Leavens KF, Liao CM, Gagne AL, Kishore S, Cardenas-Diaz FL, French DL, Gadue P. PMID: 33316598.
      View in: PubMed   Mentions:    Fields:    
    4. Generation of human control iPSC line CHOPi004-A from juvenile foreskin fibroblast cells. Stem Cell Res. 2020 Nov 07; 49:102084. Mukherjee S, Gagne AL, Maguire JA, Jobaliya CD, Mills JA, Gadue P, French DL. PMID: 33202304.
      View in: PubMed   Mentions:    Fields:    
    5. Adding Value to Clinical Toxicology Testing. J Appl Lab Med. 2020 11 01; 5(6):1145-1148. French D. PMID: 33078201.
      View in: PubMed   Mentions:    Fields:    Translation:PHPublic Health
    6. A Non-Coding Disease Modifier of Pancreatic Agenesis Identified by Genetic Correction in a Patient-Derived iPSC Line. Cell Stem Cell. 2020 Jul 02; 27(1):137-146.e6. Kishore S, De Franco E, Cardenas-Diaz FL, Letourneau-Freiberg LR, Sanyoura M, Osorio-Quintero C, French DL, Greeley SAW, Hattersley AT, Gadue P. PMID: 32442395.
      View in: PubMed   Mentions:    Fields:    
    7. The 2018 AACC/SYCL PhD Clinical Chemist Compensation Survey. J Appl Lab Med. 2020 03 01; 5(2):377-387. Bunch DR, El-Khoury JM, Colby J, Colon-Franco J, Hackenmueller SA, Olson KN, Cotten SW, Kampfrath T, Chittiprol S, Suh-Lailam B, French D, Isbell TS, Nerenz RD, Parnas ML, Tolan NV. PMID: 32445390.
      View in: PubMed   Mentions:    Fields:    
    8. Generation of Defined Genomic Modifications Using CRISPR-CAS9 in Human Pluripotent Stem Cells. J Vis Exp. 2019 09 25; (151). Cardenas-Diaz FL, Maguire JA, Gadue P, French DL. PMID: 31609348.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    9. Modeling Monogenic Diabetes using Human ESCs Reveals Developmental and Metabolic Deficiencies Caused by Mutations in HNF1A. Cell Stem Cell. 2019 08 01; 25(2):273-289.e5. Cardenas-Diaz FL, Osorio-Quintero C, Diaz-Miranda MA, Kishore S, Leavens K, Jobaliya C, Stanescu D, Ortiz-Gonzalez X, Yoon C, Chen CS, Haliyur R, Brissova M, Powers AC, French DL, Gadue P. PMID: 31374199.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    10. Serum 25-Hydroxyvitamin D Concentrations from Patient Groups at High Risk for Deficiency. J Appl Lab Med. 2019 07; 4(1):61-68. Wu AHB, Ghosh R, Mei Ong C, French D. PMID: 31639708.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    11. Development and validation of a LC-MS/MS assay for quantification of serum estradiol using calibrators with values assigned by the CDC reference measurement procedure. Clin Chim Acta. 2019 May; 492:45-49. Dowis J, Woroniecki W, French D. PMID: 30731088.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Commentary. Clin Chem. 2019 02; 65(2):241. French D. PMID: 30692137.
      View in: PubMed   Mentions:    Fields:    
    13. A Practical First Step Using Needs Assessment and a Survey Approach to Implementing a Clinical Pharmacogenomics Consult Service. J Am Coll Clin Pharm. 2019 Jun; 2(3):214-221. Zakinova A, Long-Boyle JR, French D, Croci R, Wilson L, Phillips KA, Kroetz DL, Shin J, Tamraz B. PMID: 32391517.
      View in: PubMed   Mentions:
    14. The (Sun)Light and Dark of 25-Hydroxyvitamin D Testing. J Appl Lab Med. 2018 Nov 01; 3(3):460-473. French D. PMID: 33636926.
      View in: PubMed   Mentions:    Fields:    
    15. Quantification of Serum Voriconazole, Isavuconazole, and Posaconazole by Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS). Curr Protoc Toxicol. 2018 05; 76(1):e47. Smith A, Dowis J, French D. PMID: 30040225.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    16. A Case of Opioid Overdose? Or Is It? J Appl Lab Med. 2018 Jan 01; 2(4):633-639. French D, Gerona RR. PMID: 33636892.
      View in: PubMed   Mentions:    Fields:    
    17. Advances in Clinical Mass Spectrometry. Adv Clin Chem. 2017; 79:153-198. French D. PMID: 28212711.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    18. Advances in bioanalytical techniques to measure steroid hormones in serum. Bioanalysis. 2016 Jun; 8(11):1203-19. French D. PMID: 27217264.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    19. Population pharmacokinetics of busulfan in pediatric and young adult patients undergoing hematopoietic cell transplant: a model-based dosing algorithm for personalized therapy and implementation into routine clinical use. Ther Drug Monit. 2015 Apr; 37(2):236-45. Long-Boyle JR, Savic R, Yan S, Bartelink I, Musick L, French D, Law J, Horn B, Cowan MJ, Dvorak CC. PMID: 25162216.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    20. Development and validation of a liquid chromatography-tandem mass spectrometry (LC-MS/MS) assay to quantify serum voriconazole. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Apr 01; 986-987:94-9. Mak J, Sujishi KK, French D. PMID: 25725319.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    21. Development and validation of a liquid chromatography-tandem mass spectrometry assay to quantify plasma busulfan. Ther Drug Monit. 2014 Apr; 36(2):169-74. French D, Sujishi KK, Long-Boyle JR, Ritchie JC. PMID: 24625541.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    22. The challenges of LC-MS/MS analysis of opiates and opioids in urine. Bioanalysis. 2013 Nov; 5(22):2803-20. French D. PMID: 24256360.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    23. Interpreting laboratory results in transgender patients on hormone therapy. Am J Med. 2014 Feb; 127(2):159-62. Roberts TK, Kraft CS, French D, Ji W, Wu AH, Tangpricha V, Fantz CR. PMID: 24332725.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    24. The aryl hydrocarbon receptor directs hematopoietic progenitor cell expansion and differentiation. Blood. 2013 Jul 18; 122(3):376-85. PMID: 23723449.
      View in: PubMed   Mentions:
    25. The successful implementation of a licensed data management interface between a Sunquest(®) laboratory information system and an AB SCIEX™ mass spectrometer. J Pathol Inform. 2013; 4:1. French D, Terrazas E. PMID: 23599901.
      View in: PubMed   Mentions:
    26. Direct total and free testosterone measurement by liquid chromatography tandem mass spectrometry across two different platforms. Clin Biochem. 2013 May; 46(7-8):656-64. Rhea JM, French D, Molinaro RJ. PMID: 23353132.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    27. Implementation of liquid chromatography/mass spectrometry into the clinical laboratory. Clin Chim Acta. 2013 May; 420:4-10. Wu AH, French D. PMID: 23085380.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    28. Development and validation of a serum total testosterone liquid chromatography-tandem mass spectrometry (LC-MS/MS) assay calibrated to NIST SRM 971. Clin Chim Acta. 2013 Jan 16; 415:109-17. French D. PMID: 23085208.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    29. Role of liquid chromatography-high-resolution mass spectrometry (LC-HR/MS) in clinical toxicology. Clin Toxicol (Phila). 2012 Sep; 50(8):733-42. Wu AH, Gerona R, Armenian P, French D, Petrie M, Lynch KL. PMID: 22888997.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansPHPublic Health
    30. A mixed (long- and medium-chain) triglyceride lipid emulsion extracts local anesthetic from human serum in vitro more effectively than a long-chain emulsion. Anesthesiology. 2012 Feb; 116(2):334-9. Ruan W, French D, Wong A, Drasner K, Wu AH. PMID: 22273855.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    31. Hydrophilic interaction LC-MS/MS analysis of opioids in urine: significance of glucuronide metabolites. Bioanalysis. 2011 Dec; 3(23):2603-12. French D, Wu A, Lynch K. PMID: 22136049.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    32. Partition constant and volume of distribution as predictors of clinical efficacy of lipid rescue for toxicological emergencies. Clin Toxicol (Phila). 2011 Nov; 49(9):801-9. French D, Smollin C, Ruan W, Wong A, Drasner K, Wu AH. PMID: 21981684.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansPHPublic Health
    33. PharmGKB summary: methotrexate pathway. Pharmacogenet Genomics. 2011 Oct; 21(10):679-86. Mikkelsen TS, Thorn CF, Yang JJ, Ulrich CM, French D, Zaza G, Dunnenberger HM, Marsh S, McLeod HL, Giacomini K, Becker ML, Gaedigk R, Leeder JS, Kager L, Relling MV, Evans W, Klein TE, Altman RB. PMID: 21317831.
      View in: PubMed   Mentions: 34     Fields:    Translation:Humans
    34. KRAS mutation detection in colorectal cancer by a commercially available gene chip array compares well with Sanger sequencing. Clin Chim Acta. 2011 Aug 17; 412(17-18):1578-81. French D, Smith A, Powers MP, Wu AH. PMID: 21575616.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    35. Serum verapamil concentrations before and after Intralipid® therapy during treatment of an overdose. Clin Toxicol (Phila). 2011 Apr; 49(4):340-4. French D, Armenian P, Ruan W, Wong A, Drasner K, Olson KR, Wu AH. PMID: 21563913.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    36. A case of a rapid drop in lactate. Am J Emerg Med. 2011 Mar; 29(3):351-3. French D, Branch J, Wu AH, Winston L, Fiebig EW. PMID: 21159468.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    37. Vitamin D status of county hospital patients assessed by the DiaSorin LIAISON® 25-hydroxyvitamin D assay. Clin Chim Acta. 2011 Jan 30; 412(3-4):258-62. French D, Gorgi AW, Ihenetu KU, Weeks MA, Lynch KL, Wu AH. PMID: 20965160.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    38. Lack of gamma-hydroxybutyrate prevalence among an urban emergency department population. J Anal Toxicol. 2010 Mar; 34(2):110-1. Ureda N, Ruan W, French D, Wu AH. PMID: 20223104.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    39. Germline genomic variants associated with childhood acute lymphoblastic leukemia. Nat Genet. 2009 Sep; 41(9):1001-5. Treviño LR, Yang W, French D, Hunger SP, Carroll WL, Devidas M, Willman C, Neale G, Downing J, Raimondi SC, Pui CH, Evans WE, Relling MV. PMID: 19684603.
      View in: PubMed   Mentions: 173     Fields:    Translation:HumansCells
    40. Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia. JAMA. 2009 Jan 28; 301(4):393-403. Yang JJ, Cheng C, Yang W, Pei D, Cao X, Fan Y, Pounds SB, Neale G, Treviño LR, French D, Campana D, Downing JR, Evans WE, Pui CH, Devidas M, Bowman WP, Camitta BM, Willman CL, Davies SM, Borowitz MJ, Carroll WL, Hunger SP, Relling MV. PMID: 19176441.
      View in: PubMed   Mentions: 89     Fields:    Translation:Humans
    41. Lab Medicine. Choosing the right benzodiazepine assay: impact on clinical decision making. 2009; 41(4):196-200. French D, Stone JA, Chang JS and Wu AH.
    42. Acquired variation outweighs inherited variation in whole genome analysis of methotrexate polyglutamate accumulation in leukemia. Blood. 2009 May 07; 113(19):4512-20. French D, Yang W, Cheng C, Raimondi SC, Mullighan CG, Downing JR, Evans WE, Pui CH, Relling MV. PMID: 19066393.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    43. Genetic polymorphism of inosine triphosphate pyrophosphatase is a determinant of mercaptopurine metabolism and toxicity during treatment for acute lymphoblastic leukemia. Clin Pharmacol Ther. 2009 Feb; 85(2):164-72. Stocco G, Cheok MH, Crews KR, Dervieux T, French D, Pei D, Yang W, Cheng C, Pui CH, Relling MV, Evans WE. PMID: 18685564.
      View in: PubMed   Mentions: 64     Fields:    Translation:Humans
    44. Concordant gene expression in leukemia cells and normal leukocytes is associated with germline cis-SNPs. PLoS One. 2008 May 14; 3(5):e2144. French D, Yang W, Hamilton LH, Neale G, Fan Y, Downing JR, Cox NJ, Pui CH, Evans WE, Relling MV. PMID: 18478092.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    45. A PAI-1 (SERPINE1) polymorphism predicts osteonecrosis in children with acute lymphoblastic leukemia: a report from the Children's Oncology Group. Blood. 2008 May 01; 111(9):4496-9. French D, Hamilton LH, Mattano LA, Sather HN, Devidas M, Nachman JB, Relling MV. PMID: 18285546.
      View in: PubMed   Mentions: 45     Fields:    Translation:Humans
    46. Ancestry and pharmacogenetics of antileukemic drug toxicity. Blood. 2007 May 15; 109(10):4151-7. Kishi S, Cheng C, French D, Pei D, Das S, Cook EH, Hijiya N, Rizzari C, Rosner GL, Frudakis T, Pui CH, Evans WE, Relling MV. PMID: 17264302.
      View in: PubMed   Mentions: 43     Fields:    Translation:Humans
    47. Genetic studies of a cluster of acute lymphoblastic leukemia cases in Churchill County, Nevada. Environ Health Perspect. 2007 Jan; 115(1):158-64. Steinberg KK, Relling MV, Gallagher ML, Greene CN, Rubin CS, French D, Holmes AK, Carroll WL, Koontz DA, Sampson EJ, Satten GA. PMID: 17366837.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    48. Genome-wide approach to identify risk factors for therapy-related myeloid leukemia. Leukemia. 2006 Feb; 20(2):239-46. Bogni A, Cheng C, Liu W, Yang W, Pfeffer J, Mukatira S, French D, Downing JR, Pui CH, Relling MV. PMID: 16341039.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    49. Global gene expression as a function of germline genetic variation. Hum Mol Genet. 2005 Jun 15; 14(12):1621-9. French D, Wilkinson MR, Yang W, de Chaisemartin L, Cook EH, Das S, Ratain MJ, Evans WE, Downing JR, Pui CH, Relling MV. PMID: 15857854.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    50. A preliminary evaluation of the functional significance of alpha-1-acid glycoprotein glycosylation on wound healing. Biomed Chromatogr. 2002 Sep; 16(6):412-9. French D, Watson J, McCahill B, Taggart I, Smith KD. PMID: 12228899.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    51. Papillary solid and cystic pancreatic tumor. Genetic prediction factors for malignancy: report of three cases. Anticancer Res. 2002 Jul-Aug; 22(4):2341-6. Brozzetti S, French D, Polistena A, Di Marzo L, Pisani T, Marchese R, Mingazzini P, Mascioli G, Vecchione A, Cavallaro A. PMID: 12174924.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    52. A naturally occurring mutation near the amino terminus of alphaIIb defines a new region involved in ligand binding to alphaIIbbeta3. Blood. 2000 Jan 01; 95(1):180-8. PMID: 10607701.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    53. Glycoprotein IIb Leu214Pro mutation produces glanzmann thrombasthenia with both quantitative and qualitative abnormalities in GPIIb/IIIa. Blood. 1998 Mar 01; 91(5):1562-71. PMID: 9473221.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    54. Distinct STAT structure promotes interaction of STAT2 with the p48 subunit of the interferon-alpha-stimulated transcription factor ISGF3. J Biol Chem. 1997 Aug 08; 272(32):20070-6. Martinez-Moczygemba M, Gutch MJ, French DL, Reich NC. PMID: 9242679.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    55. A Cys374Tyr homozygous mutation of platelet glycoprotein IIIa (beta 3) in a Chinese patient with Glanzmann's thrombasthenia. Blood. 1996 Sep 01; 88(5):1666-75. PMID: 8781422.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
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