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Deborah French, PhD

Title(s)Associate Professor, Laboratory Medicine
SchoolSchool of Medicine
Phone415-514-6627
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    Collapse Biography 
    Collapse Education and Training
    University of StrathclydeB.Sc.Biochemistry
    University of StrathclydePh.D.Biochemistry
    St Jude Children's Research HospitalPostdoctoral StudiesPharmaceutical Sciences
    University of California, San FranciscoPostdoctoral StudiesGraduate Division

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Cardenas-Diaz FL, Maguire JA, Gadue P, French DL. Generation of Defined Genomic Modifications Using CRISPR-CAS9 in Human Pluripotent Stem Cells. J Vis Exp. 2019 Sep 25; (151). PMID: 31609348.
      View in: PubMed
    2. Cardenas-Diaz FL, Osorio-Quintero C, Diaz-Miranda MA, Kishore S, Leavens K, Jobaliya C, Stanescu D, Ortiz-Gonzalez X, Yoon C, Chen CS, Haliyur R, Brissova M, Powers AC, French DL, Gadue P. Modeling Monogenic Diabetes using Human ESCs Reveals Developmental and Metabolic Deficiencies Caused by Mutations in HNF1A. Cell Stem Cell. 2019 Aug 01; 25(2):273-289.e5. PMID: 31374199.
      View in: PubMed
    3. Wu AHB, Ghosh R, Mei Ong C, French D. Serum 25-Hydroxyvitamin D Concentrations from Patient Groups at High Risk for Deficiency. J Appl Lab Med. 2019 07; 4(1):61-68. PMID: 31639708.
      View in: PubMed
    4. Dowis J, Woroniecki W, French D. Development and validation of a LC-MS/MS assay for quantification of serum estradiol using calibrators with values assigned by the CDC reference measurement procedure. Clin Chim Acta. 2019 May; 492:45-49. PMID: 30731088.
      View in: PubMed
    5. French D. Commentary. Clin Chem. 2019 Feb; 65(2):241. PMID: 30692137.
      View in: PubMed
    6. Smith A, Dowis J, French D. Quantification of Serum Voriconazole, Isavuconazole, and Posaconazole by Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS). Curr Protoc Toxicol. 2018 05; 76(1):e47. PMID: 30040225.
      View in: PubMed
    7. French D. Advances in Clinical Mass Spectrometry. Adv Clin Chem. 2017; 79:153-198. PMID: 28212711.
      View in: PubMed
    8. French D. Advances in bioanalytical techniques to measure steroid hormones in serum. Bioanalysis. 2016 Jun; 8(11):1203-19. PMID: 27217264.
      View in: PubMed
    9. Long-Boyle JR, Savic R, Yan S, Bartelink I, Musick L, French D, Law J, Horn B, Cowan MJ, Dvorak CC. Population pharmacokinetics of busulfan in pediatric and young adult patients undergoing hematopoietic cell transplant: a model-based dosing algorithm for personalized therapy and implementation into routine clinical use. Ther Drug Monit. 2015 Apr; 37(2):236-45. PMID: 25162216.
      View in: PubMed
    10. Mak J, Sujishi KK, French D. Development and validation of a liquid chromatography-tandem mass spectrometry (LC-MS/MS) assay to quantify serum voriconazole. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Apr 01; 986-987:94-9. PMID: 25725319.
      View in: PubMed
    11. French D, Sujishi KK, Long-Boyle JR, Ritchie JC. Development and validation of a liquid chromatography-tandem mass spectrometry assay to quantify plasma busulfan. Ther Drug Monit. 2014 Apr; 36(2):169-74. PMID: 24625541.
      View in: PubMed
    12. French D. The challenges of LC-MS/MS analysis of opiates and opioids in urine. Bioanalysis. 2013 Nov; 5(22):2803-20. PMID: 24256360.
      View in: PubMed
    13. Roberts TK, Kraft CS, French D, Ji W, Wu AH, Tangpricha V, Fantz CR. Interpreting laboratory results in transgender patients on hormone therapy. Am J Med. 2014 Feb; 127(2):159-62. PMID: 24332725.
      View in: PubMed
    14. French D, Terrazas E. The successful implementation of a licensed data management interface between a Sunquest(®) laboratory information system and an AB SCIEX™ mass spectrometer. J Pathol Inform. 2013; 4:1. PMID: 23599901.
      View in: PubMed
    15. Rhea JM, French D, Molinaro RJ. Direct total and free testosterone measurement by liquid chromatography tandem mass spectrometry across two different platforms. Clin Biochem. 2013 May; 46(7-8):656-64. PMID: 23353132.
      View in: PubMed
    16. Wu AH, French D. Implementation of liquid chromatography/mass spectrometry into the clinical laboratory. Clin Chim Acta. 2013 May; 420:4-10. PMID: 23085380.
      View in: PubMed
    17. French D. Development and validation of a serum total testosterone liquid chromatography-tandem mass spectrometry (LC-MS/MS) assay calibrated to NIST SRM 971. Clin Chim Acta. 2013 Jan 16; 415:109-17. PMID: 23085208.
      View in: PubMed
    18. Wu AH, Gerona R, Armenian P, French D, Petrie M, Lynch KL. Role of liquid chromatography-high-resolution mass spectrometry (LC-HR/MS) in clinical toxicology. Clin Toxicol (Phila). 2012 Sep; 50(8):733-42. PMID: 22888997.
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    19. Ruan W, French D, Wong A, Drasner K, Wu AH. A mixed (long- and medium-chain) triglyceride lipid emulsion extracts local anesthetic from human serum in vitro more effectively than a long-chain emulsion. Anesthesiology. 2012 Feb; 116(2):334-9. PMID: 22273855.
      View in: PubMed
    20. French D, Wu A, Lynch K. Hydrophilic interaction LC-MS/MS analysis of opioids in urine: significance of glucuronide metabolites. Bioanalysis. 2011 Dec; 3(23):2603-12. PMID: 22136049.
      View in: PubMed
    21. French D, Smollin C, Ruan W, Wong A, Drasner K, Wu AH. Partition constant and volume of distribution as predictors of clinical efficacy of lipid rescue for toxicological emergencies. Clin Toxicol (Phila). 2011 Nov; 49(9):801-9. PMID: 21981684.
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    22. Mikkelsen TS, Thorn CF, Yang JJ, Ulrich CM, French D, Zaza G, Dunnenberger HM, Marsh S, McLeod HL, Giacomini K, Becker ML, Gaedigk R, Leeder JS, Kager L, Relling MV, Evans W, Klein TE, Altman RB. PharmGKB summary: methotrexate pathway. Pharmacogenet Genomics. 2011 Oct; 21(10):679-86. PMID: 21317831.
      View in: PubMed
    23. French D, Smith A, Powers MP, Wu AH. KRAS mutation detection in colorectal cancer by a commercially available gene chip array compares well with Sanger sequencing. Clin Chim Acta. 2011 Aug 17; 412(17-18):1578-81. PMID: 21575616.
      View in: PubMed
    24. French D, Armenian P, Ruan W, Wong A, Drasner K, Olson KR, Wu AH. Serum verapamil concentrations before and after Intralipid® therapy during treatment of an overdose. Clin Toxicol (Phila). 2011 Apr; 49(4):340-4. PMID: 21563913.
      View in: PubMed
    25. French D, Branch J, Wu AH, Winston L, Fiebig EW. A case of a rapid drop in lactate. Am J Emerg Med. 2011 Mar; 29(3):351-3. PMID: 21159468.
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    26. French D, Gorgi AW, Ihenetu KU, Weeks MA, Lynch KL, Wu AH. Vitamin D status of county hospital patients assessed by the DiaSorin LIAISON® 25-hydroxyvitamin D assay. Clin Chim Acta. 2011 Jan 30; 412(3-4):258-62. PMID: 20965160.
      View in: PubMed
    27. Ureda N, Ruan W, French D, Wu AH. Lack of gamma-hydroxybutyrate prevalence among an urban emergency department population. J Anal Toxicol. 2010 Mar; 34(2):110-1. PMID: 20223104.
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    28. Treviño LR, Yang W, French D, Hunger SP, Carroll WL, Devidas M, Willman C, Neale G, Downing J, Raimondi SC, Pui CH, Evans WE, Relling MV. Germline genomic variants associated with childhood acute lymphoblastic leukemia. Nat Genet. 2009 Sep; 41(9):1001-5. PMID: 19684603.
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    29. Yang JJ, Cheng C, Yang W, Pei D, Cao X, Fan Y, Pounds SB, Neale G, Treviño LR, French D, Campana D, Downing JR, Evans WE, Pui CH, Devidas M, Bowman WP, Camitta BM, Willman CL, Davies SM, Borowitz MJ, Carroll WL, Hunger SP, Relling MV. Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia. JAMA. 2009 Jan 28; 301(4):393-403. PMID: 19176441.
      View in: PubMed
    30. French D, Stone JA, Chang JS and Wu AH.Lab Medicine. Choosing the right benzodiazepine assay: impact on clinical decision making. 2009; 41(4):196-200.
    31. French D, Yang W, Cheng C, Raimondi SC, Mullighan CG, Downing JR, Evans WE, Pui CH, Relling MV. Acquired variation outweighs inherited variation in whole genome analysis of methotrexate polyglutamate accumulation in leukemia. Blood. 2009 May 07; 113(19):4512-20. PMID: 19066393.
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    32. Stocco G, Cheok MH, Crews KR, Dervieux T, French D, Pei D, Yang W, Cheng C, Pui CH, Relling MV, Evans WE. Genetic polymorphism of inosine triphosphate pyrophosphatase is a determinant of mercaptopurine metabolism and toxicity during treatment for acute lymphoblastic leukemia. Clin Pharmacol Ther. 2009 Feb; 85(2):164-72. PMID: 18685564.
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    33. French D, Yang W, Hamilton LH, Neale G, Fan Y, Downing JR, Cox NJ, Pui CH, Evans WE, Relling MV. Concordant gene expression in leukemia cells and normal leukocytes is associated with germline cis-SNPs. PLoS One. 2008 May 14; 3(5):e2144. PMID: 18478092.
      View in: PubMed
    34. French D, Hamilton LH, Mattano LA, Sather HN, Devidas M, Nachman JB, Relling MV. A PAI-1 (SERPINE1) polymorphism predicts osteonecrosis in children with acute lymphoblastic leukemia: a report from the Children's Oncology Group. Blood. 2008 May 01; 111(9):4496-9. PMID: 18285546.
      View in: PubMed
    35. Kishi S, Cheng C, French D, Pei D, Das S, Cook EH, Hijiya N, Rizzari C, Rosner GL, Frudakis T, Pui CH, Evans WE, Relling MV. Ancestry and pharmacogenetics of antileukemic drug toxicity. Blood. 2007 May 15; 109(10):4151-7. PMID: 17264302.
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    36. Steinberg KK, Relling MV, Gallagher ML, Greene CN, Rubin CS, French D, Holmes AK, Carroll WL, Koontz DA, Sampson EJ, Satten GA. Genetic studies of a cluster of acute lymphoblastic leukemia cases in Churchill County, Nevada. Environ Health Perspect. 2007 Jan; 115(1):158-64. PMID: 17366837.
      View in: PubMed
    37. Bogni A, Cheng C, Liu W, Yang W, Pfeffer J, Mukatira S, French D, Downing JR, Pui CH, Relling MV. Genome-wide approach to identify risk factors for therapy-related myeloid leukemia. Leukemia. 2006 Feb; 20(2):239-46. PMID: 16341039.
      View in: PubMed
    38. French D, Wilkinson MR, Yang W, de Chaisemartin L, Cook EH, Das S, Ratain MJ, Evans WE, Downing JR, Pui CH, Relling MV. Global gene expression as a function of germline genetic variation. Hum Mol Genet. 2005 Jun 15; 14(12):1621-9. PMID: 15857854.
      View in: PubMed
    39. French D, Watson J, McCahill B, Taggart I, Smith KD. A preliminary evaluation of the functional significance of alpha-1-acid glycoprotein glycosylation on wound healing. Biomed Chromatogr. 2002 Sep; 16(6):412-9. PMID: 12228899.
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    40. Martinez-Moczygemba M, Gutch MJ, French DL, Reich NC. Distinct STAT structure promotes interaction of STAT2 with the p48 subunit of the interferon-alpha-stimulated transcription factor ISGF3. J Biol Chem. 1997 Aug 08; 272(32):20070-6. PMID: 9242679.
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