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Alan Wu, PhD

TitleProfessor
InstitutionUniversity of California San Francisco
DepartmentLaboratory Medicine
Address1001 Potrero Ave, SFGH 5
San Francisco CA 94110
Phone415-206-3540
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    Alan Wu has several areas of expertise. He is chief of the clinical chemistry and toxicology laboratories at San Francisco General Hospital. In this capacity, his clinical and research laboratory conducts testing for routine analytes in blood, urine and cerebral spinal fluid for electrolytes, metabolites, hormones, proteins, and biomarkers. His particular area of interest is in cardiac biomarkers for acute cardiac diseases (troponin, B-type natriuretic peptide, and novel biomarkers of ACS and heart failure).

    The toxicology laboratory has expertise and analytic equipment for quantitation of drugs and other small molecules in biological fluids. Using liquid chromatography (LC) /time-of-flight (TOF) mass spectrometry (MS), this laboratory is able to conduct unknown searches for chemicals in these samples based on high resolution molecular weight (2-5 ppm), enabling the assignment of precise molecular formula. The LC/TOF-MS is ideal for detection of unknown drugs, chemicals and specimens. Recently, this laboratory has expanded its services to include analysis of medications both pharmaceuticals and nutriceuticals (herbals) and street preparations for the presence of adulterants, contaminants, and supplements. Once tentatively identified, the toxicology laboratory has LC-tandem MS capability for quantitation in the pg/mL concentrations.

    Dr. Wu is also chief of the clinical pharmacogenomics laboratory and offers a clinical service and clinical research in pharmacogenomic for genomic targets such as cytochrome p450 2D6, 2C9, 2C19, vitamin K receptor complex, UDP glucuronsyltransferase, kif-6, and HLA-B*5710, 1502, and 5801. These targets for important for certain therapeutic drugs such as tamoxifen, codeine, antidepressants, warfarin, clopidogrel, irinotecan, statins, abacavir, carbamazepine, phenytoin, and allopurinol, respectively.


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Putterman C, Pisetsky DS, Petri M, Caricchio R, Wu A, Sanz I, Oates JC, Wallace S, Sorek R, Gerwien R, Safer P, Jakobi-Brook K, Cohen IR. The SLE-key test serological signature: new insights into the course of lupus. Rheumatology (Oxford). 2018 Jun 04. PMID: 29873771.
      View in: PubMed
    2. Rosenbaum MW, Flood JG, Melanson SEF, Baumann NA, Marzinke MA, Rai AJ, Hayden J, Wu A, Ladror M, Lifshitz MS, Scott MG, Peck-Palmer OM, Bowen R, Babic N, Sobhani K, Giacherio D, Bocsi GT, Herman DS, Wang P, Toffaletti J, Handel E, Kelly KA, Albeiroti S, Wang S, Zimmer M, Driver B, Yi X, Wilburn C, Lewandrowski KB. Quality Control Practices for Chemistry and Immunochemistry in a Cohort of 21 Large Academic Medical Centers. Am J Clin Pathol. 2018 May 29. PMID: 29850771.
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    3. Wu A. The influence of pharmacogenomics on the protective effect of light-to-moderate alcohol use. Per Med. 2018 May 23. PMID: 29790828.
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    4. Beri N, Daniels LB, Jaffe A, Mueller C, Anand I, Peacock WF, Hollander JE, DeFilippi C, Schreiber D, McCord J, Limkakeng AT, Wu A, Apple FS, Diercks DB, Nagurney JT, Nowak RM, Cannon CM, Clopton P, Neath SX, Christenson RH, Hogan C, Vilke G, Maisel A. Copeptin to rule out myocardial infarction in Blacks versus Caucasians. Eur Heart J Acute Cardiovasc Care. 2018 May 01; 2048872618772500. PMID: 29737180.
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    5. Rodda LN, Volk JA, Moffat E, Williams CM, Lynch KL, Wu A. Evaluation of Intraosseous Fluid as an Alternative Biological Specimen in Postmortem Toxicology. J Anal Toxicol. 2018 Apr 01; 42(3):163-169. PMID: 29272445.
      View in: PubMed
    6. Gartrell RD, Marks DK, Hart TD, Li G, Davari DR, Wu A, Blake Z, Lu Y, Askin KN, Monod A, Esancy CL, Stack EC, Jia DT, Armenta PM, Fu Y, Izaki D, Taback B, Rabadan R, Kaufman HL, Drake CG, Horst BA, Saenger YM. Quantitative Analysis of Immune Infiltrates in Primary Melanoma. Cancer Immunol Res. 2018 Apr; 6(4):481-493. PMID: 29467127.
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    7. Clancy CJ, Pappas PG, Vazquez J, Judson MA, Kontoyiannis DP, Thompson GR, Garey KW, Reboli A, Greenberg RN, Apewokin S, Lyon GM, Ostrosky-Zeichner L, Wu A, Tobin E, Nguyen MH, Caliendo AM. Detecting Infections Rapidly and Easily for Candidemia Trial, Part 2 (DIRECT2): A Prospective, Multicenter Study of the T2Candida Panel. Clin Infect Dis. 2018 Feb 09. PMID: 29438475.
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    8. Wu A. Pharmacogenomic-guided dosing for warfarin: too little too late? Per Med. 2018 Mar; 15(2):71-73. PMID: 29714120.
      View in: PubMed
    9. Wu A, Christenson RH, Greene DN, Jaffe AS, Kavsak PA, Ordonez-Llanos J, Apple FS. Clinical Laboratory Practice Recommendations for the Use of Cardiac Troponin in Acute Coronary Syndrome: Expert Opinion from the Academy of the American Association for Clinical Chemistry and the Task Force on Clinical Applications of Cardiac Bio-Markers of the International Federation of Clinical Chemistry and Laboratory Medicine. Clin Chem. 2018 Apr; 64(4):645-655. PMID: 29343532.
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    10. Madasamy S, Liu D, Lundry J, Alderete B, Kong R, Robinson JP, Wu A, Amento EP. Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles. J Vis Exp. 2017 Nov 10; (129). PMID: 29155776.
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    11. Vo KT, Horng H, Li K, Ho RY, Wu A, Lynch KL, Smollin CG. Cannabis Intoxication Case Series: The Dangers of Edibles Containing Tetrahydrocannabinol. Ann Emerg Med. 2018 Mar; 71(3):306-313. PMID: 29103798.
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    12. Thakar M, Angira F, Pattanapanyasat K, Wu A, O'Gorman M, Zeng H, Qu C, Mahajan B, Sukapirom K, Chen D, Hao Y, Gong Y, Indig MA, Graminske S, Orta D, d'Empaire N, Lu B, Omana-Zapata I, Zeh C. CD4 Lymphocyte Enumeration and Hemoglobin Assessment Aid for Priority Decisions: A Multisite Evaluation of the BD FACSPresto™ System. Open AIDS J. 2017; 11:76-90. PMID: 29290885.
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    13. Estis J, Wu A, Todd J, Bishop J, Sandlund J, Kavsak PA. Comprehensive Age and Sex 99th Percentiles for a High-Sensitivity Cardiac Troponin I Assay. Clin Chem. 2018 Feb; 64(2):398-399. PMID: 29046331.
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    14. Bartelink IH, Prideaux B, Krings G, Wilmes L, Lee PRE, Bo P, Hann B, Coppé JP, Heditsian D, Swigart-Brown L, Jones EF, Magnitsky S, Keizer RJ, de Vries N, Rosing H, Pawlowska N, Thomas S, Dhawan M, Aggarwal R, Munster PN, Esserman LJ, Ruan W, Wu A, Yee D, Dartois V, Savic RM, Wolf DM, van 't Veer L. Heterogeneous drug penetrance of veliparib and carboplatin measured in triple negative breast tumors. Breast Cancer Res. 2017 Sep 11; 19(1):107. PMID: 28893315.
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    15. Miao J, Friedman E, Wu A, Todd JA, Estis J, Xu X, Nolan N, Bishop JJ, Lenihan DJ. Clinical utility of single molecule counting technology for quantification of KIM-1 in patients with heart failure and chronic kidney disease. Clin Biochem. 2017 Nov; 50(16-17):889-895. PMID: 28614696.
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    16. Mishra RK, Judson G, Christenson RH, DeFilippi C, Wu A, Whooley MA. The Association of Five-Year Changes in the Levels of N-Terminal Fragment of the Prohormone Brain-Type Natriuretic Peptide (NT-proBNP) with Subsequent Heart Failure and Death in Patients with Stable Coronary Artery Disease: The Heart and Soul Study. Cardiology. 2017; 137(4):201-206. PMID: 28445886.
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    17. Li K, van Wijk XMR, Hayashi S, Lynch KL, Wu A, Smollin CG. Anticholinergic toxicity associated with ingestion of water containing lupini bean extract. Clin Toxicol (Phila). 2017 Aug; 55(7):687-688. PMID: 28443353.
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    18. van Wijk XMR, Vittinghoff E, Wu A, Lynch KL, Riley ED. Cocaine use is associated with a higher prevalence of elevated ST2 concentrations. Clin Biochem. 2017 Sep; 50(13-14):791-793. PMID: 28442257.
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    19. Kavsak PA, Jaffe AS, Greene DN, Christenson RH, Apple FS, Wu A. Total Analytic Error for Low Cardiac Troponin Concentrations (=10 ng/L) by Use of a High-Sensitivity Cardiac Troponin Assay. Clin Chem. 2017 May; 63(5):1043-1045. PMID: 28325814.
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    20. Riley ED, Hsue PY, Vittinghoff E, Wu A, Coffin PO, Moore PK, Lynch KL. Higher prevalence of detectable troponin I among cocaine-users without known cardiovascular disease. Drug Alcohol Depend. 2017 03 01; 172:88-93. PMID: 28157591.
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    21. Wu A. Personalized justice: the potential use of genotyping in wrongful death investigations. Per Med. 2017 Jan; 14(1):9-12. PMID: 29749822.
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    22. Beri N, Marston NA, Daniels LB, Nowak RM, Schreiber D, Mueller C, Jaffe A, Diercks DB, Wettersten N, DeFilippi C, Peacock WF, Limkakeng AT, Anand I, McCord J, Hollander JE, Wu A, Apple FS, Nagurney JT, Berardi C, Cannon CM, Clopton P, Neath SX, Christenson RH, Hogan C, Vilke G, Maisel A. Necessity of hospitalization and stress testing in low risk chest pain patients. Am J Emerg Med. 2017 Feb; 35(2):274-280. PMID: 27847253.
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    23. Meijers WC, van der Velde AR, Muller Kobold AC, Dijck-Brouwer J, Wu A, Jaffe A, de Boer RA. Variability of biomarkers in patients with chronic heart failure and healthy controls. Eur J Heart Fail. 2017 03; 19(3):357-365. PMID: 27766733.
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    24. Vo KT, van Wijk XM, Wu A, Lynch KL, Ho RY. Synthetic agents off the darknet: a case of U-47700 and phenazepam abuse. Clin Toxicol (Phila). 2017 Jan; 55(1):71-72. PMID: 27736261.
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    25. van Wijk XMR, Magee CA, Wu A, Tana MM, Lynch KL. A comparison of methods for evaluation of a case of suspected macro-aspartate aminotransferase. Clin Chim Acta. 2016 Dec 01; 463:1-3. PMID: 27732874.
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    26. Arens AM, van Wijk XM, Vo KT, Lynch KL, Wu A, Smollin CG. Adverse Effects From Counterfeit Alprazolam Tablets. JAMA Intern Med. 2016 Oct 01; 176(10):1554-1555. PMID: 27532131.
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    27. Madasamy S, Shivasubramani U, Villanueva J, Bigos M, Amento EP, Wu A. Nonenzymatic Mechanism of Statins in Modulating Cholesterol Particles Formation. Am J Cardiol. 2016 Oct 15; 118(8):1187-1193. PMID: 27614849.
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    28. Wu A. High-sensitivity cardiac troponin testing for primary care: analytical assay considerations required before widespread implementation. Ann Transl Med. 2016 Jul; 4(13):251. PMID: 27501115; PMCID: PMC4958729.
    29. Ruaño G, Seip R, Windemuth A, Wu A, Thompson PD. Laboratory Medicine in the Clinical Decision Support for Treatment of Hypercholesterolemia: Pharmacogenetics of Statins. Clin Lab Med. 2016 Sep; 36(3):473-91. PMID: 27514463; PMCID: PMC4987540 [Available on 09/01/17].
    30. Vo KT, van Wijk XM, Lynch KL, Wu A, Smollin CG. Counterfeit Norco Poisoning Outbreak - San Francisco Bay Area, California, March 25-April 5, 2016. MMWR Morb Mortal Wkly Rep. 2016 Apr 29; 65(16):420-3. PMID: 27123589.
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    31. Yang HS, Wu A, Lynch KL. Development and Validation of a Novel LC-MS/MS Opioid Confirmation Assay: Evaluation of ß-glucuronidase Enzymes and Sample Cleanup Methods. J Anal Toxicol. 2016 Jun; 40(5):323-9. PMID: 27121711.
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    32. Sandoval Y, Herzog CA, Love SA, Cao J, Hu Y, Wu A, Gilbertson D, Brunelli SM, Young A, Ler R, Apple FS. Prognostic Value of Serial Changes in High-Sensitivity Cardiac Troponin I and T over 3 Months Using Reference Change Values in Hemodialysis Patients. Clin Chem. 2016 Apr; 62(4):631-8. PMID: 26847217.
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    33. Wu A, Christenson RH. The standards for reporting diagnostic accuracy studies 2015 update: is there a missing link to the triumvirate? Ann Transl Med. 2016 Feb; 4(3):44. PMID: 26904566; PMCID: PMC4739997.
    34. Yang HS, Wu A, Johnson-Davis KL, Lynch KL. Development and validation of an LC-MS/MS sulfonylurea assay for hypoglycemia cases in the emergency department. Clin Chim Acta. 2016 Feb 15; 454:130-4. PMID: 26790752.
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    35. Wu A, Colby J. High-Resolution Mass Spectrometry for Untargeted Drug Screening. Methods Mol Biol. 2016; 1383:153-66. PMID: 26660184.
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    36. Oh SS, Galanter J, Thakur N, Pino-Yanes M, Barcelo NE, White MJ, de Bruin DM, Greenblatt RM, Bibbins-Domingo K, Wu A, Borrell LN, Gunter C, Powe NR, Burchard EG. Diversity in Clinical and Biomedical Research: A Promise Yet to Be Fulfilled. PLoS Med. 2015 Dec; 12(12):e1001918. PMID: 26671224; PMCID: PMC4679830.
    37. Putterman C, Wu A, Reiner-Benaim A, Batty DS, Sanz I, Oates J, Jakobi K, Petri M, Safer P, Gerwien R, Sorek R, Blumenstein Y, Cohen IR. SLE-key(®) rule-out serologic test for excluding the diagnosis of systemic lupus erythematosus: Developing the ImmunArray iCHIP(®). J Immunol Methods. 2016 Feb; 429:1-6. PMID: 26678162; PMCID: PMC4824168 [Available on 02/01/17].
    38. Thoren KL, Colby JM, Shugarts SB, Wu A, Lynch KL. Comparison of Information-Dependent Acquisition on a Tandem Quadrupole TOF vs a Triple Quadrupole Linear Ion Trap Mass Spectrometer for Broad-Spectrum Drug Screening. Clin Chem. 2016 Jan; 62(1):170-8. PMID: 26453698.
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    39. Korley FK, Diaz-Arrastia R, Wu A, Yue JK, Manley GT, Sair HI, Van Eyk J, Everett AD. Circulating Brain-Derived Neurotrophic Factor Has Diagnostic and Prognostic Value in Traumatic Brain Injury. J Neurotrauma. 2016 Jan 15; 33(2):215-25. PMID: 26159676; PMCID: PMC4722554 [Available on 01/15/17].
    40. Secemsky EA, Scherzer R, Nitta E, Wu A, Lange DC, Deeks SG, Martin JN, Snider J, Ganz P, Hsue PY. Novel Biomarkers of Cardiac Stress, Cardiovascular Dysfunction, and Outcomes in HIV-Infected Individuals. JACC Heart Fail. 2015 Aug; 3(8):591-9. PMID: 26164679; PMCID: PMC4529774.
    41. Marston NA, Shah KS, Mueller C, Neath SX, Christenson RH, McCord J, Nowak RM, Daniels LB, Hollander JE, Apple F, Nagurney J, Schreiber D, deFilippi C, Diercks D, Limkakeng A, Anand IS, Wu A, Jaffe AS, Peacock WF, Maisel AS. Serial sampling of copeptin levels improves diagnosis and risk stratification in patients presenting with chest pain: results from the CHOPIN trial. Emerg Med J. 2016 Jan; 33(1):23-9. PMID: 26105583.
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    42. Wu A, White MJ, Oh S, Burchard E. The Hawaii clopidogrel lawsuit: the possible effect on clinical laboratory testing. Per Med. 2015 Jun; 12(3):179-181. PMID: 29771642.
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    43. Shah KS, Marston NA, Mueller C, Neath SX, Christenson RH, McCord J, Nowak RM, Vilke GM, Daniels LB, Hollander JE, Apple FS, Cannon CM, Nagurney J, Schreiber D, deFilippi C, Hogan CJ, Diercks DB, Limkakeng A, Anand IS, Wu A, Clopton P, Jaffe AS, Peacock WF, Maisel AS. Midregional proadrenomedullin predicts mortality and major adverse cardiac events in patients presenting with chest pain: results from the CHOPIN trial. Acad Emerg Med. 2015 May; 22(5):554-63. PMID: 25908114.
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    44. Maxwell NM, Nevin RL, Stahl S, Block J, Shugarts S, Wu A, Dominy S, Solano-Blanco MA, Kappelman-Culver S, Lee-Messer C, Maldonado J, Maxwell AJ. Prolonged neuropsychiatric effects following management of chloroquine intoxication with psychotropic polypharmacy. Clin Case Rep. 2015 Jun; 3(6):379-87. PMID: 26185633; PMCID: PMC4498847.
    45. Aw TC, van Wijk XM, Wu A, Jaffe AS. Release of cardiac troponin using a high sensitivity assay after exercise: Type 2 acute myocardial infarction? Clin Chim Acta. 2015 Jun 15; 446:6-8. PMID: 25862921.
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    46. Colby JM, Wu A, Lynch KL. Analysis of codeine positivity in urine of pain management patients. J Anal Toxicol. 2015 Jun; 39(5):407-10. PMID: 25840440.
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    47. Wu A. Pharmacogenomic testing and response to warfarin. Lancet. 2015 Jun 06; 385(9984):2231-2. PMID: 25769360.
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    48. Wu A, Khalili M. The birth and potential death of IL28B genotyping for hepatitis C therapy. Per Med. 2015 Mar; 12(2):55-57. PMID: 29754535.
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    49. Wu A. Analytical validation of novel cardiac biomarkers used in clinical trials. Am Heart J. 2015 May; 169(5):674-83. PMID: 25965715.
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    50. Wu A, Hamilton R, Middleberg R, Kacinko S, Kearney T. Investigation of postmortem absorption and redistribution after the application of a fentanyl patch. J Forensic Sci. 2015 Mar; 60(2):532-5. PMID: 25676881.
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    51. Wu A, Hale K. Predicting mortality after elective open-heart surgery using midregional-proadrenomedullin: is it time to scalp Acute Physiology and Chronic Health Evaluation IV? Crit Care Med. 2015 Feb; 43(2):494-5. PMID: 25599481.
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    52. Madasamy S, Chaudhuri V, Kong R, Alderete B, Adams CM, Knaak TD, Ruan W, Wu A, Bigos M, Amento EP. Plaque array method and proteomics-based identification of biomarkers from Alzheimer's disease serum. Clin Chim Acta. 2015 Feb 20; 441:79-85. PMID: 25532947.
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    53. Hussan JR, Hunter PJ, Gladding PA, Greenberg N, Christie R, Wu A, Sorby H, Thomas JD. ICMA: an integrated cardiac modeling and analysis platform. Bioinformatics. 2015 Apr 15; 31(8):1331-3. PMID: 25481009; PMCID: PMC4393521.
    54. Wu A, van Wijk XM. A new ultra-high sensitivity troponin I assay for chest pain patients with no evidence of troponin I using a conventional assay. Clin Biochem. 2015 Mar; 48(4-5):358-9. PMID: 25482854.
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    55. Lipinski MJ, Baker NC, Escárcega RO, Torguson R, Chen F, Aldous SJ, Christ M, Collinson PO, Goodacre SW, Mair J, Inoue K, Lotze U, Sebbane M, Cristol JP, Freund Y, Chenevier-Gobeaux C, Meune C, Eggers KM, Pracon R, Schreiber DH, Wu A, Ordoñez-Llanos J, Jaffe AS, Twerenbold R, Mueller C, Waksman R. Comparison of conventional and high-sensitivity troponin in patients with chest pain: a collaborative meta-analysis. Am Heart J. 2015 Jan; 169(1):6-16.e6. PMID: 25497242.
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    56. Wu A. Folate testing: time to retire your VCR. JAMA Intern Med. 2014 Oct; 174(10):1697-8. PMID: 25111459.
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    57. Storrow AB, Nowak RM, Diercks DB, Singer AJ, Wu A, Kulstad E, LoVecchio F, Fromm C, Headden G, Potis T, Hogan CJ, Schrock JW, Zelinski DP, Greenberg MR, Christenson RH, Ritchie JC, Chamberlin JS, Bray KR, Rhodes DW, Trainor D, Southwick PC. Absolute and relative changes (delta) in troponin I for early diagnosis of myocardial infarction: Results of a prospective multicenter trial. Clin Biochem. 2015 Mar; 48(4-5):260-7. PMID: 25261587.
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    58. Wang BT, Colby JM, Wu A, Lynch KL. Cross-reactivity of acetylfentanyl and risperidone with a fentanyl immunoassay. J Anal Toxicol. 2014 Nov-Dec; 38(9):672-5. PMID: 25248490.
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    59. Storrow AB, Christenson RH, Nowak RM, Diercks DB, Singer AJ, Wu A, Kulstad E, LoVecchio F, Fromm C, Headden G, Potis T, Hogan CJ, Schrock JW, Zelinski DP, Greenberg MR, Ritchie JC, Chamberlin JS, Bray KR, Rhodes DW, Trainor D, Holmes D, Southwick PC. Diagnostic performance of cardiac Troponin I for early rule-in and rule-out of acute myocardial infarction: Results of a prospective multicenter trial. Clin Biochem. 2015 Mar; 48(4-5):254-9. PMID: 25195101.
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    60. Wu A, Yang HS, Thoren K. Biological variation of the osmolality and the osmolal gap. Clin Biochem. 2014 Oct; 47(15):130-1. PMID: 25130958.
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    61. Apple FS, Hollander J, Wu A, Jaffe AS. Improving the 510(k) FDA process for cardiac troponin assays: in search of common ground. Clin Chem. 2014 Oct; 60(10):1273-5. PMID: 25114274.
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    62. Mishra RK, Beatty AL, Jaganath R, Regan M, Wu A, Whooley MA. B-type natriuretic peptides for the prediction of cardiovascular events in patients with stable coronary heart disease: the Heart and Soul Study. J Am Heart Assoc. 2014 Jul 22; 3(4). PMID: 25053234; PMCID: PMC4310375.
    63. Finlay JA, Wu A. Biological variation of immunoglobulin heavy chain-light chain pairs in serum. Clin Chim Acta. 2014 Sep 25; 436:68-71. PMID: 24824555.
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    64. Wu A, Superko HR. The pharmacogenomics of warfarin from the COAG and EU-PACT: where do we go from here? Per Med. 2014 May; 11(3):247-249. PMID: 29764060.
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    65. Wu A. Biomarkers for cholesterol absorption and synthesis in hyperlipidemic patients: role for therapeutic selection. Clin Lab Med. 2014 Mar; 34(1):157-66, viii. PMID: 24507794.
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    66. Wu A, Ruan W, Todd J, Lynch KL. Biological variation of ß-sitosterol, campesterol, and lathosterol as cholesterol absorption and synthesis biomarkers. Clin Chim Acta. 2014 Mar 20; 430:43-7. PMID: 24394292.
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    67. Neath SX, Jefferies JL, Berger JS, Wu A, McConnell JP, Boone JL, McCullough PA, Jesse RL, Maisel AS. The current and future landscape of urinary thromboxane testing to evaluate atherothrombotic risk. Rev Cardiovasc Med. 2014; 15(2):119-30. PMID: 25051129.
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    68. Wu A. Biological and analytical variation of clinical biomarker testing: implications for biomarker-guided therapy. Curr Heart Fail Rep. 2013 Dec; 10(4):434-40. PMID: 24037380.
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    69. Roberts TK, Kraft CS, French D, Ji W, Wu A, Tangpricha V, Fantz CR. Interpreting laboratory results in transgender patients on hormone therapy. Am J Med. 2014 Feb; 127(2):159-62. PMID: 24332725.
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    70. Wu A, Kearney T. Lack of impairment due to confirmed codeine use prior to a motor vehicle accident: role of pharmacogenomics. J Forensic Leg Med. 2013 Nov; 20(8):1024-7. PMID: 24237812.
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    71. Ruddy KJ, Desantis SD, Gelman RS, Wu A, Punglia RS, Mayer EL, Tolaney SM, Winer EP, Partridge AH, Burstein HJ. Personalized medicine in breast cancer: tamoxifen, endoxifen, and CYP2D6 in clinical practice. Breast Cancer Res Treat. 2013 Oct; 141(3):421-7. PMID: 24062210.
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    72. Wu A. Genotype and phenotype concordance for pharmacogenetic tests through proficiency survey testing. Arch Pathol Lab Med. 2013 Sep; 137(9):1232-6. PMID: 23991737.
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    73. Lung DD, Scott BJ, Wu A, Gerona RR. Prolonged ventilatory failure and flaccid quadriparesis after ingestion of poison hemlock. Muscle Nerve. 2013 Nov; 48(5):823-7. PMID: 23733387.
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    74. Kim Y, Smith A, Wu A. C3435T polymorphism of MDR1 gene with warfarin resistance. Clin Chim Acta. 2013 Oct 21; 425:34-6. PMID: 23872171.
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    75. Lung DD, Wu A, Gerona RR. Cardiotoxicity in a citalopram and olanzapine overdose. J Emerg Med. 2013 Oct; 45(4):554-8. PMID: 23871479.
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    76. Smith A, Wu A, Lynch KL, Ko N, Grenache DG. Multi-wavelength spectrophotometric analysis for detection of xanthochromia in cerebrospinal fluid and accuracy for the diagnosis of subarachnoid hemorrhage. Clin Chim Acta. 2013 Sep 23; 424:231-6. PMID: 23800427.
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    77. Perera MA, Cavallari LH, Limdi NA, Gamazon ER, Konkashbaev A, Daneshjou R, Pluzhnikov A, Crawford DC, Wang J, Liu N, Tatonetti N, Bourgeois S, Takahashi H, Bradford Y, Burkley BM, Desnick RJ, Halperin JL, Khalifa SI, Langaee TY, Lubitz SA, Nutescu EA, Oetjens M, Shahin MH, Patel SR, Sagreiya H, Tector M, Weck KE, Rieder MJ, Scott SA, Wu A, Burmester JK, Wadelius M, Deloukas P, Wagner MJ, Mushiroda T, Kubo M, Roden DM, Cox NJ, Altman RB, Klein TE, Nakamura Y, Johnson JA. Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study. Lancet. 2013 Aug 31; 382(9894):790-6. PMID: 23755828; PMCID: PMC3759580.
    78. Richards M, Di Somma S, Mueller C, Nowak R, Peacock WF, Ponikowski P, Mockel M, Hogan C, Wu A, Clopton P, Filippatos GS, Anand I, Ng L, Daniels LB, Neath SX, Shah K, Christenson R, Hartmann O, Anker SD, Maisel A. Atrial fibrillation impairs the diagnostic performance of cardiac natriuretic peptides in dyspneic patients: results from the BACH Study (Biomarkers in ACute Heart Failure). JACC Heart Fail. 2013 Jun; 1(3):192-9. PMID: 24621869.
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    79. Maisel A, Mueller C, Neath SX, Christenson RH, Morgenthaler NG, McCord J, Nowak RM, Vilke G, Daniels LB, Hollander JE, Apple FS, Cannon C, Nagurney JT, Schreiber D, deFilippi C, Hogan C, Diercks DB, Stein JC, Headden G, Limkakeng AT, Anand I, Wu A, Papassotiriou J, Hartmann O, Ebmeyer S, Clopton P, Jaffe AS, Peacock WF. Copeptin helps in the early detection of patients with acute myocardial infarction: primary results of the CHOPIN trial (Copeptin Helps in the early detection Of Patients with acute myocardial INfarction). J Am Coll Cardiol. 2013 Jul 09; 62(2):150-160. PMID: 23643595.
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    80. Wu A, Christenson RH. Analytical and assay issues for use of cardiac troponin testing for risk stratification in primary care. Clin Biochem. 2013 Aug; 46(12):969-78. PMID: 23623945.
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