Jean-Marc Schwarz, PhD

Title(s)Professor, Medicine
SchoolSchool of Medicine
Address2540 23rd Street, #4408
San Francisco CA 94110
Phone628-206-5533
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    1. Effects of Consuming Beverages Sweetened with Fructose, Glucose, High-Fructose Corn Syrup, Sucrose, or Aspartame on OGTT-Derived Indices of Insulin Sensitivity in Young Adults. Nutrients. 2024 Jan 02; 16(1). Hieronimus B, Medici V, Lee V, Nunez MV, Sigala DM, Bremer AA, Cox CL, Keim NL, Schwarz JM, Pacini G, Tura A, Havel PJ, Stanhope KL. PMID: 38201980; PMCID: PMC10780640.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    2. Dolutegravir use over 48 weeks is not associated with worsening insulin resistance and pancreatic beta cell function in a cohort of HIV-infected Ugandan adults. AIDS Res Ther. 2023 09 09; 20(1):65. Mulindwa F, Castelnuovo B, Brusselaers N, Nabwana M, Bollinger R, Buzibye A, Agnes Odongpiny EL, Kiguba R, Schwarz JM. PMID: 37689695; PMCID: PMC10492310.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    3. Dolutegravir use over 48 weeks is not associated with worsening insulin resistance and pancreatic beta cell function in a cohort of HIV-infected Ugandan adults. Res Sq. 2023 Jul 20. Mulindwa F, Castelnuovo B, Brusselaers N, Nabwana M, Bollinger R, Laker E, Kiguba R, Schwarz JM. PMID: 37502917; PMCID: PMC10371155.
      View in: PubMed   Mentions:
    4. Implementation of longitudinal insulin kinetic studies in busy field settings in Uganda: experience from the "glucose metabolism changes in Ugandan HIV patients on dolutegravir based anti-retroviral therapy" (GLUMED study). Pan Afr Med J. 2023; 44:184. Mulindwa F, Schwarz JM, Brusselaers N, Dujanga S, Yendewa G, Castelnuovo B. PMID: 37484585; PMCID: PMC10362648.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Effects of Isocaloric Fructose Restriction on Ceramide Levels in Children with Obesity and Cardiometabolic Risk: Relation to Hepatic De Novo Lipogenesis and Insulin Sensitivity. Nutrients. 2022 Mar 30; 14(7). Olson E, Suh JH, Schwarz JM, Noworolski SM, Jones GM, Barber JR, Erkin-Cakmak A, Mulligan K, Lustig RH, Mietus-Snyder M. PMID: 35406045; PMCID: PMC9002884.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCellsCTClinical Trials
    6. Association between integrase strand transfer inhibitor (INSTIs) use with insulin resistance and incident diabetes mellitus in persons living with HIV: A systematic review and meta-analysis protocol. PLoS One. 2022; 17(3):e0264792. Mulindwa F, Kamal H, Castelnuovo B, Bollinger RC, Schwarz JM, Brussealers N. PMID: 35235607; PMCID: PMC8890726.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    7. Separation of postprandial lipoproteins: improved purification of chylomicrons using an ApoB100 immunoaffinity method. J Lipid Res. 2020 03; 61(3):455-463. Jones GM, Caccavello R, Palii SP, Pullinger CR, Kane JP, Mulligan K, Gugliucci A, Schwarz JM. PMID: 31888979; PMCID: PMC7053834.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    8. Isocaloric Fructose Restriction Reduces Serum d-Lactate Concentration in Children With Obesity and Metabolic Syndrome. J Clin Endocrinol Metab. 2019 07 01; 104(7):3003-3011. Erkin-Cakmak A, Bains Y, Caccavello R, Noworolski SM, Schwarz JM, Mulligan K, Lustig RH, Gugliucci A. PMID: 30869790; PMCID: PMC6553815.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    9. Dietary carbohydrates and fatty liver disease: de novo lipogenesis. Curr Opin Clin Nutr Metab Care. 2018 07; 21(4):277-282. Chiu S, Mulligan K, Schwarz JM. PMID: 29697539.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    10. Conversion of Sugar to Fat: Is Hepatic de Novo Lipogenesis Leading to Metabolic Syndrome and Associated Chronic Diseases? J Am Osteopath Assoc. 2017 Aug 01; 117(8):520-527. Schwarz JM, Clearfield M, Mulligan K. PMID: 28759094.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    11. Effects of Dietary Fructose Restriction on Liver Fat, De Novo Lipogenesis, and Insulin Kinetics in Children With Obesity. Gastroenterology. 2017 09; 153(3):743-752. Schwarz JM, Noworolski SM, Erkin-Cakmak A, Korn NJ, Wen MJ, Tai VW, Jones GM, Palii SP, Velasco-Alin M, Pan K, Patterson BW, Gugliucci A, Lustig RH, Mulligan K. PMID: 28579536; PMCID: PMC5813289.
      View in: PubMed   Mentions: 110     Fields:    Translation:HumansCells
    12. Short-term isocaloric fructose restriction lowers apoC-III levels and yields less atherogenic lipoprotein profiles in children with obesity and metabolic syndrome. Atherosclerosis. 2016 10; 253:171-177. Gugliucci A, Lustig RH, Caccavello R, Erkin-Cakmak A, Noworolski SM, Tai VW, Wen MJ, Mulligan K, Schwarz JM. PMID: 27451002.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCTClinical Trials
    13. In vivo triglyceride synthesis in subcutaneous adipose tissue of humans correlates with plasma HDL parameters. Atherosclerosis. 2016 08; 251:147-152. Tuvdendorj D, Munoz AO, Ruiz-Barros V, Schwarz JM, Montalto G, Chandalia M, Sowers LC, Rizzo M, Murphy EJ, Abate N. PMID: 27323227; PMCID: PMC4983221.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    14. Isocaloric fructose restriction and metabolic improvement in children with obesity and metabolic syndrome. Obesity (Silver Spring). 2016 Feb; 24(2):453-60. Lustig RH, Mulligan K, Noworolski SM, Tai VW, Wen MJ, Erkin-Cakmak A, Gugliucci A, Schwarz JM. PMID: 26499447; PMCID: PMC4736733.
      View in: PubMed   Mentions: 79     Fields:    Translation:Humans
    15. Effect of a High-Fructose Weight-Maintaining Diet on Lipogenesis and Liver Fat. J Clin Endocrinol Metab. 2015 Jun; 100(6):2434-42. Schwarz JM, Noworolski SM, Wen MJ, Dyachenko A, Prior JL, Weinberg ME, Herraiz LA, Tai VW, Bergeron N, Bersot TP, Rao MN, Schambelan M, Mulligan K. PMID: 25825943; PMCID: PMC4454806.
      View in: PubMed   Mentions: 99     Fields:    Translation:HumansCellsCTClinical Trials
    16. Subchronic sleep restriction causes tissue-specific insulin resistance. J Clin Endocrinol Metab. 2015 Apr; 100(4):1664-71. Rao MN, Neylan TC, Grunfeld C, Mulligan K, Schambelan M, Schwarz JM. PMID: 25658017; PMCID: PMC4399283.
      View in: PubMed   Mentions: 61     Fields:    Translation:Humans
    17. Thermogenic changes after gastric bypass, adjustable gastric banding or diet alone. Surgery. 2014 Oct; 156(4):806-12. Rabl C, Rao MN, Schwarz JM, Mulligan K, Campos GM. PMID: 25239323; PMCID: PMC4171693.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCTClinical Trials
    18. Effects of the absence of apolipoprotein e on lipoproteins, neurocognitive function, and retinal function. JAMA Neurol. 2014 Oct; 71(10):1228-36. Mak AC, Pullinger CR, Tang LF, Wong JS, Deo RC, Schwarz JM, Gugliucci A, Movsesyan I, Ishida BY, Chu C, Poon A, Kim P, Stock EO, Schaefer EJ, Asztalos BF, Castellano JM, Wyss-Coray T, Duncan JL, Miller BL, Kane JP, Kwok PY, Malloy MJ. PMID: 25111166; PMCID: PMC4714860.
      View in: PubMed   Mentions: 47     Fields:    Translation:Humans
    19. Effect of 8 weeks of overfeeding on ectopic fat deposition and insulin sensitivity: testing the "adipose tissue expandability" hypothesis. Diabetes Care. 2014 Oct; 37(10):2789-97. Johannsen DL, Tchoukalova Y, Tam CS, Covington JD, Xie W, Schwarz JM, Bajpeyi S, Ravussin E. PMID: 25011943; PMCID: PMC4170127.
      View in: PubMed   Mentions: 78     Fields:    Translation:HumansCellsCTClinical Trials
    20. Effects of Artemisia species on de novo lipogenesis in vivo. Nutrition. 2014 Jul-Aug; 30(7-8 Suppl):S17-20. Rood JC, Schwarz JM, Gettys T, Mynatt RL, Mendoza T, Johnson WD, Cefalu WT. PMID: 24985100; PMCID: PMC4120075.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    21. Ten nights of moderate hypoxia improves insulin sensitivity in obese humans. Diabetes Care. 2013 Dec; 36(12):e197-8. Lecoultre V, Peterson CM, Covington JD, Ebenezer PJ, Frost EA, Schwarz JM, Ravussin E. PMID: 24265370; PMCID: PMC3836149.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimals
    22. Changes in post-prandial glucose and pancreatic hormones, and steady-state insulin and free fatty acids after gastric bypass surgery. Surg Obes Relat Dis. 2014 Jan-Feb; 10(1):1-8. Campos GM, Rabl C, Havel PJ, Rao M, Schwarz JM, Schambelan M, Mulligan K. PMID: 24209879; PMCID: PMC3896512.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    23. Adverse metabolic effects of dietary fructose: results from the recent epidemiological, clinical, and mechanistic studies. Curr Opin Lipidol. 2013 Jun; 24(3):198-206. Stanhope KL, Schwarz JM, Havel PJ. PMID: 23594708; PMCID: PMC4251462.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansCells
    24. Consumption of fructose- but not glucose-sweetened beverages for 10 weeks increases circulating concentrations of uric acid, retinol binding protein-4, and gamma-glutamyl transferase activity in overweight/obese humans. Nutr Metab (Lond). 2012 Jul 24; 9(1):68. Cox CL, Stanhope KL, Schwarz JM, Graham JL, Hatcher B, Griffen SC, Bremer AA, Berglund L, McGahan JP, Keim NL, Havel PJ. PMID: 22828276; PMCID: PMC3463498.
      View in: PubMed   Mentions: 70  
    25. Circulating concentrations of monocyte chemoattractant protein-1, plasminogen activator inhibitor-1, and soluble leukocyte adhesion molecule-1 in overweight/obese men and women consuming fructose- or glucose-sweetened beverages for 10 weeks. J Clin Endocrinol Metab. 2011 Dec; 96(12):E2034-8. Cox CL, Stanhope KL, Schwarz JM, Graham JL, Hatcher B, Griffen SC, Bremer AA, Berglund L, McGahan JP, Keim NL, Havel PJ. PMID: 21956423; PMCID: PMC3232623.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    26. Metabolic responses to prolonged consumption of glucose- and fructose-sweetened beverages are not associated with postprandial or 24-h glucose and insulin excursions. Am J Clin Nutr. 2011 Jul; 94(1):112-9. Stanhope KL, Griffen SC, Bremer AA, Vink RG, Schaefer EJ, Nakajima K, Schwarz JM, Beysen C, Berglund L, Keim NL, Havel PJ. PMID: 21613559; PMCID: PMC3127512.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCTClinical Trials
    27. Boosting dose ritonavir does not alter peripheral insulin sensitivity in healthy HIV-seronegative volunteers. J Acquir Immune Defic Syndr. 2010 Nov; 55(3):361-4. Taylor SA, Lee GA, Pao VY, Anthonypillai J, Aweeka FT, Schwarz JM, Mulligan K, Schambelan M, Grunfeld C. PMID: 20595906; PMCID: PMC3164483.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    28. Effects of insulin-like growth factor (IGF)-I/IGF-binding protein-3 treatment on glucose metabolism and fat distribution in human immunodeficiency virus-infected patients with abdominal obesity and insulin resistance. J Clin Endocrinol Metab. 2010 Sep; 95(9):4361-6. Rao MN, Mulligan K, Tai V, Wen MJ, Dyachenko A, Weinberg M, Li X, Lang T, Grunfeld C, Schwarz JM, Schambelan M. PMID: 20610601; PMCID: PMC2936071.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCellsCTClinical Trials
    29. Reduced oxygenation in human obese adipose tissue is associated with impaired insulin suppression of lipolysis. J Clin Endocrinol Metab. 2010 Aug; 95(8):4052-5. Pasarica M, Rood J, Ravussin E, Schwarz JM, Smith SR, Redman LM. PMID: 20466783; PMCID: PMC2913036.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCellsCTClinical Trials
    30. The role of fructose in the pathogenesis of NAFLD and the metabolic syndrome. Nat Rev Gastroenterol Hepatol. 2010 May; 7(5):251-64. Lim JS, Mietus-Snyder M, Valente A, Schwarz JM, Lustig RH. PMID: 20368739.
      View in: PubMed   Mentions: 309     Fields:    Translation:Humans
    31. The protease inhibitor combination lopinavir/ritonavir does not decrease insulin secretion in healthy, HIV-seronegative volunteers. AIDS. 2010 Jan 16; 24(2):265-70. Pao VY, Lee GA, Taylor S, Aweeka FT, Schwarz JM, Mulligan K, Schambelan M, Grunfeld C. PMID: 19890203.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    32. Improvement in peripheral glucose uptake after gastric bypass surgery is observed only after substantial weight loss has occurred and correlates with the magnitude of weight lost. J Gastrointest Surg. 2010 Jan; 14(1):15-23. Campos GM, Rabl C, Peeva S, Ciovica R, Rao M, Schwarz JM, Havel P, Schambelan M, Mulligan K. PMID: 19838759; PMCID: PMC2793380.
      View in: PubMed   Mentions: 87     Fields:    Translation:Humans
    33. The acute effects of HIV protease inhibitors on insulin suppression of glucose production in healthy HIV-negative men. J Acquir Immune Defic Syndr. 2009 Oct 01; 52(2):246-8. Lee GA, Schwarz JM, Patzek S, Kim S, Dyachenko A, Wen M, Mulligan K, Schambelan M, Grunfeld C. PMID: 19680131; PMCID: PMC3164488.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    34. Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans. J Clin Invest. 2009 May; 119(5):1322-34. Stanhope KL, Schwarz JM, Keim NL, Griffen SC, Bremer AA, Graham JL, Hatcher B, Cox CL, Dyachenko A, Zhang W, McGahan JP, Seibert A, Krauss RM, Chiu S, Schaefer EJ, Ai M, Otokozawa S, Nakajima K, Nakano T, Beysen C, Hellerstein MK, Berglund L, Havel PJ. PMID: 19381015; PMCID: PMC2673878.
      View in: PubMed   Mentions: 658     Fields:    Translation:Humans
    35. The effects of recombinant human leptin on visceral fat, dyslipidemia, and insulin resistance in patients with human immunodeficiency virus-associated lipoatrophy and hypoleptinemia. J Clin Endocrinol Metab. 2009 Apr; 94(4):1137-44. Mulligan K, Khatami H, Schwarz JM, Sakkas GK, DePaoli AM, Tai VW, Wen MJ, Lee GA, Grunfeld C, Schambelan M. PMID: 19174500; PMCID: PMC2682465.
      View in: PubMed   Mentions: 47     Fields:    Translation:Humans
    36. Effects of ritonavir and amprenavir on insulin sensitivity in healthy volunteers. AIDS. 2007 Oct 18; 21(16):2183-90. Lee GA, Rao M, Mulligan K, Lo JC, Aweeka F, Schwarz JM, Schambelan M, Grunfeld C. PMID: 18090045; PMCID: PMC3167072.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    37. Single-dose lopinavir-ritonavir acutely inhibits insulin-mediated glucose disposal in healthy volunteers. Clin Infect Dis. 2006 Sep 01; 43(5):658-60. Lee GA, Lo JC, Aweeka F, Schwarz JM, Mulligan K, Schambelan M, Grunfeld C. PMID: 16886163; PMCID: PMC3205942.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    38. Metabolic effects of parenteral nutrition enriched with n-3 polyunsaturated fatty acids in critically ill patients. Clin Nutr. 2006 Aug; 25(4):588-95. Tappy L, Berger MM, Schwarz JM, Schneiter P, Kim S, Revelly JP, Chioléro R. PMID: 16697496.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    39. Effect of fructose overfeeding and fish oil administration on hepatic de novo lipogenesis and insulin sensitivity in healthy men. Diabetes. 2005 Jul; 54(7):1907-13. Faeh D, Minehira K, Schwarz JM, Periasamy R, Periasami R, Park S, Seongsu P, Tappy L. PMID: 15983189.
      View in: PubMed   Mentions: 133     Fields:    Translation:Humans
    40. Indinavir increases glucose production in healthy HIV-negative men. AIDS. 2004 Sep 03; 18(13):1852-4. Schwarz JM, Lee GA, Park S, Noor MA, Lee J, Wen M, Lo JC, Mulligan K, Schambelan M, Grunfeld C. PMID: 15316349.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    41. The effects of low-dose growth hormone in HIV-infected men with fat accumulation: a pilot study. Clin Infect Dis. 2004 Sep 01; 39(5):732-5. Lo JC, Mulligan K, Noor MA, Lee GA, Schwarz JM, Grunfeld C, Schambelan M. PMID: 15356790; PMCID: PMC3170406.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    42. HIV protease inhibitors increase adiponectin levels in HIV-negative men. J Acquir Immune Defic Syndr. 2004 May 01; 36(1):645-7. Lee GA, Mafong DD, Noor MA, Lo JC, Mulligan K, Schwarz JM, Schambelan M, Grunfeld C. PMID: 15097312.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    43. The metabolic effects of lopinavir/ritonavir in HIV-negative men. AIDS. 2004 Mar 05; 18(4):641-9. Lee GA, Seneviratne T, Noor MA, Lo JC, Schwarz JM, Aweeka FT, Mulligan K, Schambelan M, Grunfeld C. PMID: 15090769; PMCID: PMC3166345.
      View in: PubMed   Mentions: 48     Fields:    Translation:Humans
    44. Hepatic de novo lipogenesis in normoinsulinemic and hyperinsulinemic subjects consuming high-fat, low-carbohydrate and low-fat, high-carbohydrate isoenergetic diets. Am J Clin Nutr. 2003 Jan; 77(1):43-50. Schwarz JM, Linfoot P, Dare D, Aghajanian K. PMID: 12499321.
      View in: PubMed   Mentions: 176     Fields:    Translation:HumansCTClinical Trials
    45. Measurement of gluconeogenesis in exercising men by mass isotopomer distribution analysis. J Appl Physiol (1985). 2002 Jul; 93(1):233-41. Trimmer JK, Schwarz JM, Casazza GA, Horning MA, Rodriguez N, Brooks GA. PMID: 12070210.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCellsCTClinical Trials
    46. Indinavir acutely inhibits insulin-stimulated glucose disposal in humans: a randomized, placebo-controlled study. AIDS. 2002 Mar 29; 16(5):F1-8. Noor MA, Seneviratne T, Aweeka FT, Lo JC, Schwarz JM, Mulligan K, Schambelan M, Grunfeld C. PMID: 11964551; PMCID: PMC3166537.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCTClinical Trials
    47. Effects of recombinant human growth hormone on hepatic lipid and carbohydrate metabolism in HIV-infected patients with fat accumulation. J Clin Endocrinol Metab. 2002 Feb; 87(2):942. Schwarz JM, Mulligan K, Lee J, Lo JC, Wen M, Noor MA, Grunfeld C, Schambelan M. PMID: 11836345.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
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