Jennifer Fung, PhD

TitleAssociate Professor
InstitutionUniversity of California San Francisco
DepartmentOb/Gyn, Reproductive Sciences
Address600 16th Street
San Francisco CA 94158
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoPh.D.1996 Graduate Division (Biophysics)

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Modeling and Analysis of Meiotic Homolog Pairing
    NIH/NIGMS R01GM116895Jun 8, 2016 - Mar 31, 2020
    Role: Principal Investigator
    Upgrading the OMX microscope for extended live imaging and fast live 3-D structur
    NIH S10OD010673May 15, 2012 - May 14, 2013
    Role: Principal Investigator
    Kinetics of Chromosome Synapsis During Meiosis
    NIH/NIGMS R01GM097213Mar 15, 2011 - Feb 29, 2016
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Websites
    Collapse In The News

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Arter M, Hurtado-Nieves V, Oke A, Zhuge T, Wettstein R, Fung J, Blanco MG, Matos J. Regulated Crossing-Over Requires Inactivation of Yen1/GEN1 Resolvase during Meiotic Prophase I. Dev Cell. 2018 Jun 18; 45(6):785-800.e6. PMID: 29920281.
      View in: PubMed
    2. Fung J. Kinetochores: Importance of Being Fashionably Late. Cell Syst. 2017 Jun 28; 4(6):585-586. PMID: 28662384.
      View in: PubMed
    3. Pollard MG, Fung J. In Vivo Imaging of Budding Yeast Meiosis. Methods Mol Biol. 2017; 1471:175-186. PMID: 28349396.
      View in: PubMed
    4. Marshall WF, Fung J. Modeling meiotic chromosome pairing: nuclear envelope attachment, telomere-led active random motion, and anomalous diffusion. Phys Biol. 2016 Apr 05; 13(2):026003. PMID: 27046097.
      View in: PubMed
    5. Sousa Martins JP, Liu X, Oke A, Arora R, Franciosi F, Viville S, Laird DJ, Fung J, Conti M. DAZL and CPEB1 regulate mRNA translation synergistically during oocyte maturation. J Cell Sci. 2016 Mar 15; 129(6):1271-82. PMID: 26826184; PMCID: PMC4813292 [Available on 03/15/17].
    6. Marshall WM, Fung J. Modeling meiotic chromosome pairing: nuclear envelope attachment, telomere-led active random motion, and anomalous diffusion. Journal of Physical Biology. 2016.
    7. Vincenten N, Kuhl LM, Lam I, Oke A, Kerr AR, Hochwagen A, Fung J, Keeney S, Vader G, Marston AL. The kinetochore prevents centromere-proximal crossover recombination during meiosis. Elife. 2015 Dec 14; 4. PMID: 26653857.
      View in: PubMed
    8. Anderson CM, Oke A, Yam P, Zhuge T, Fung J. Reduced Crossover Interference and Increased ZMM-Independent Recombination in the Absence of Tel1/ATM. PLoS Genet. 2015 Aug; 11(8):e1005478. PMID: 26305689; PMCID: PMC4549261.
    9. Faire M, Skillern A, Arora R, Nguyen DH, Wang J, Chamberlain C, German MS, Fung J, Laird DJ. Follicle dynamics and global organization in the intact mouse ovary. Dev Biol. 2015 Jul 01; 403(1):69-79. PMID: 25889274; PMCID: PMC4469539.
    10. Osman C, Noriega TR, Okreglak V, Fung J, Walter P. Integrity of the yeast mitochondrial genome, but not its distribution and inheritance, relies on mitochondrial fission and fusion. Proc Natl Acad Sci U S A. 2015 Mar 03; 112(9):E947-56. PMID: 25730886; PMCID: PMC4352819.
    11. Oke A, Anderson CM, Yam P, Fung J. Controlling meiotic recombinational repair - specifying the roles of ZMMs, Sgs1 and Mus81/Mms4 in crossover formation. PLoS Genet. 2014 Oct; 10(10):e1004690. PMID: 25329811; PMCID: PMC4199502.
    12. Liu Y, Gaines WA, Callender T, Busygina V, Oke A, Sung P, Fung J, Hollingsworth NM. Down-regulation of Rad51 activity during meiosis in yeast prevents competition with Dmc1 for repair of double-strand breaks. PLoS Genet. 2014 Jan; 10(1):e1004005. PMID: 24465215; PMCID: PMC3900393.
    13. Rockmill B, Lefran├žois P, Voelkel-Meiman K, Oke A, Roeder GS, Fung J. High throughput sequencing reveals alterations in the recombination signatures with diminishing Spo11 activity. PLoS Genet. 2013 Oct; 9(10):e1003932. PMID: 24204324; PMCID: PMC3814317.
    14. Arigovindan M, Fung J, Elnatan D, Mennella V, Chan YH, Pollard M, Branlund E, Sedat JW, Agard DA. High-resolution restoration of 3D structures from widefield images with extreme low signal-to-noise-ratio. Proc Natl Acad Sci U S A. 2013 Oct 22; 110(43):17344-9. PMID: 24106307; PMCID: PMC3808589.
    15. Rafelski SM, Viana MP, Zhang Y, Chan YH, Thorn KS, Yam P, Fung J, Li H, Costa Lda F, Marshall WF. Mitochondrial network size scaling in budding yeast. Science. 2012 Nov 09; 338(6108):822-4. PMID: 23139336; PMCID: PMC3602416.
    16. Anderson CM, Chen SY, Dimon MT, Oke A, DeRisi JL, Fung J. ReCombine: a suite of programs for detection and analysis of meiotic recombination in whole-genome datasets. PLoS One. 2011; 6(10):e25509. PMID: 22046241; PMCID: PMC3201961.
    17. Chen SY, Fung J. Mapping of crossover sites using DNA microarrays. Methods Mol Biol. 2011; 745:117-34. PMID: 21660692.
      View in: PubMed
    18. Costanzo V, Chaudhuri J, Fung J, Moran JV. Dealing with dangerous accidents: DNA double-strand breaks take centre stage. Symposium on Genome Instability and DNA Repair. EMBO Rep. 2009 Aug; 10(8):837-42. PMID: 19609319; PMCID: PMC2726687.
    19. Chen SY, Tsubouchi T, Rockmill B, Sandler JS, Richards DR, Vader G, Hochwagen A, Roeder GS, Fung J. Global analysis of the meiotic crossover landscape. Dev Cell. 2008 Sep; 15(3):401-15. PMID: 18691940; PMCID: PMC2628562.
    20. Fung J, Rockmill B, Odell M, Roeder GS. Imposition of crossover interference through the nonrandom distribution of synapsis initiation complexes. Cell. 2004 Mar 19; 116(6):795-802. PMID: 15035982.
      View in: PubMed
    21. Rockmill B, Fung J, Branda SS, Roeder GS. The Sgs1 helicase regulates chromosome synapsis and meiotic crossing over. Curr Biol. 2003 Nov 11; 13(22):1954-62. PMID: 14614820.
      View in: PubMed
    22. Fung J, Marshall WF, Dernburg A, Agard DA, Sedat JW. Homologous chromosome pairing in Drosophila melanogaster proceeds through multiple independent initiations. J Cell Biol. 1998 Apr 06; 141(1):5-20. PMID: 9531544; PMCID: PMC2132734.
    23. Marshall WF, Fung J, Sedat JW. Deconstructing the nucleus: global architecture from local interactions. Curr Opin Genet Dev. 1997 Apr; 7(2):259-63. PMID: 9115425.
      View in: PubMed
    24. Dernburg AF, Broman KW, Fung J, Marshall WF, Philips J, Agard DA, Sedat JW. Perturbation of nuclear architecture by long-distance chromosome interactions. Cell. 1996 May 31; 85(5):745-59. PMID: 8646782.
      View in: PubMed
    25. Fung J, Liu W, de Ruijter WJ, Chen H, Abbey CK, Sedat JW, Agard DA .Toward fully automated high-resolution electron tomography. Journal of Structural Biology. 1996; 116(1):181-9.
    26. Moritz M, Braunfeld MB, Fung J, Sedat JW, Alberts BM, Agard DA. Three-dimensional structural characterization of centrosomes from early Drosophila embryos. J Cell Biol. 1995 Sep; 130(5):1149-59. PMID: 7657699; PMCID: PMC2120545.