Joshua Barrios, PhD

Title(s)Assistant Professor, Medicine
SchoolSchool of Medicine
Address675 Nelson Rising Lane, #352
San Francisco CA 94158
ORCID ORCID Icon0000-0003-1618-6244 Additional info
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    University of Utah, Salt Lake CityPh.D.11/2019Neuroscience

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    Dr. Barrios earned his Ph.D. in Neuroscience from the University of Utah, where his work focused on dopaminergic modulation of sensorimotor behavior. His interest in computational and systems neuroscience and love for engineering naturally led him to study artificial deep neural networks. Currently, his work in the Tison lab involves development of deep learning systems for clinical and biomedical applications.

    Research interests: Dr. Barrios brings together expertise in physiology, systems neuroscience, and advanced machine learning algorithms to automate clinical processes, expand diagnostic utility of existing clinical tests, and elucidate mechanisms of disease. He has developed multiple deep learning based systems for automated detection of diseases such as mitral valve prolapse, hypertrophic cardiomyopathy, and pulmonary hypertension from electrocardiograms, echocardiograms, and other clinical data modalities. His work aims to improve the sensitivity of our health system as a whole, increasing early detection of disease and the efficacy of preventative care.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Continuous Atrial Fibrillation Monitoring From Photoplethysmography: Comparison Between Supervised Deep Learning and Heuristic Signal Processing. JACC Clin Electrophysiol. 2024 Feb; 10(2):334-345. Antiperovitch P, Mortara D, Barrios J, Avram R, Yee K, Khaless AN, Cristal A, Tison G, Olgin J. PMID: 38340117.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Patient-Level Artificial Intelligence-Enhanced Electrocardiography in Hypertrophic Cardiomyopathy: Longitudinal Treatment and Clinical Biomarker Correlations. JACC Adv. 2023 Oct; 2(8). Siontis KC, Abreau S, Attia ZI, Barrios JP, Dewland TA, Agarwal P, Balasubramanyam A, Li Y, Lester SJ, Masri A, Wang A, Sehnert AJ, Edelberg JM, Abraham TP, Friedman PA, Olgin JE, Noseworthy PA, Tison GH. PMID: 38076758; PMCID: PMC10702858.
      View in: PubMed   Mentions:
    3. CathAI: fully automated coronary angiography interpretation and stenosis estimation. NPJ Digit Med. 2023 Aug 11; 6(1):142. Avram R, Olgin JE, Ahmed Z, Verreault-Julien L, Wan A, Barrios J, Abreau S, Wan D, Gonzalez JE, Tardif JC, So DY, Soni K, Tison GH. PMID: 37568050; PMCID: PMC10421915.
      View in: PubMed   Mentions: 1  
    4. Identifying Mitral Valve Prolapse at Risk for Arrhythmias and Fibrosis From Electrocardiograms Using Deep Learning. JACC Adv. 2023 Aug; 2(6). Tison GH, Abreau S, Barrios J, Lim LJ, Yang M, Crudo V, Shah DJ, Nguyen T, Hu G, Dixit S, Nah G, Arya F, Bibby D, Lee Y, Delling FN. PMID: 37936601; PMCID: PMC10629907.
      View in: PubMed   Mentions:
    5. Identification of supraventricular tachycardia mechanisms with surface electrocardiograms using a convolutional neural network. Heart Rhythm O2. 2023 Aug; 4(8):491-499. Higuchi S, Li R, Gerstenfeld EP, Liem LB, Im SI, Kalantarian S, Ansari M, Abreau S, Barrios J, Scheinman MM, Tison GH. PMID: 37645266; PMCID: PMC10461210.
      View in: PubMed   Mentions:
    6. Automated Assessment of Cardiac Systolic Function From Coronary Angiograms With Video-Based Artificial Intelligence Algorithms. JAMA Cardiol. 2023 06 01; 8(6):586-594. Avram R, Barrios JP, Abreau S, Goh CY, Ahmed Z, Chung K, So DY, Olgin JE, Tison GH. PMID: 37163297; PMCID: PMC10267763.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    7. Deep learning augmented ECG analysis to identify biomarker-defined myocardial injury. Sci Rep. 2023 02 27; 13(1):3364. Chaudhari GR, Mayfield JJ, Barrios JP, Abreau S, Avram R, Olgin JE, Tison GH. PMID: 36849487; PMCID: PMC9969952.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Electrocardiogram Detection of Pulmonary Hypertension Using Deep Learning. J Card Fail. 2023 07; 29(7):1017-1028. Aras MA, Abreau S, Mills H, Radhakrishnan L, Klein L, Mantri N, Rubin B, Barrios J, Chehoud C, Kogan E, Gitton X, Nnewihe A, Quinn D, Bridges C, Butte AJ, Olgin JE, Tison GH. PMID: 36706977; PMCID: PMC10363571.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    9. Advancing cardiovascular medicine with machine learning: Progress, potential, and perspective. Cell Rep Med. 2022 Dec 20; 3(12):100869. Barrios JP, Tison GH. PMID: 36543095.
      View in: PubMed   Mentions: 2     Fields:    
    10. Worldwide physical activity trends since COVID-19 onset. Lancet Glob Health. 2022 10; 10(10):e1381-e1382. Tison GH, Barrios J, Avram R, Kuhar P, Bostjancic B, Marcus GM, Pletcher MJ, Olgin JE. PMID: 36057269; PMCID: PMC9432866.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    11. Deep Learning Electrocardiographic Analysis for Detection of Left-Sided Valvular Heart Disease. J Am Coll Cardiol. 2022 08 09; 80(6):613-626. Elias P, Poterucha TJ, Rajaram V, Moller LM, Rodriguez V, Bhave S, Hahn RT, Tison G, Abreau SA, Barrios J, Torres JN, Hughes JW, Perez MV, Finer J, Kodali S, Khalique O, Hamid N, Schwartz A, Homma S, Kumaraiah D, Cohen DJ, Maurer MS, Einstein AJ, Nazif T, Leon MB, Perotte AJ. PMID: 35926935.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    12. Regenerated interneurons integrate into locomotor circuitry following spinal cord injury. Exp Neurol. 2021 08; 342:113737. Vasudevan D, Liu YC, Barrios JP, Wheeler MK, Douglass AD, Dorsky RI. PMID: 33957107.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    13. Hypothalamic Dopamine Neurons Control Sensorimotor Behavior by Modulating Brainstem Premotor Nuclei in Zebrafish. Curr Biol. 2020 12 07; 30(23):4606-4618.e4. Barrios JP, Wang WC, England R, Reifenberg E, Douglass AD. PMID: 33007241; PMCID: PMC7726012.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    14. Zebrafish oxytocin neurons drive nocifensive behavior via brainstem premotor targets. Nat Neurosci. 2019 09; 22(9):1477-1492. Wee CL, Nikitchenko M, Wang WC, Luks-Morgan SJ, Song E, Gagnon JA, Randlett O, Bianco IH, Lacoste AMB, Glushenkova E, Barrios JP, Schier AF, Kunes S, Engert F, Douglass AD. PMID: 31358991; PMCID: PMC6820349.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    15. Zebrafish expression reporters and mutants reveal that the IgSF cell adhesion molecule Dscamb is required for feeding and survival. J Neurogenet. 2018 12; 32(4):336-352. Julien DP, Chan AW, Barrios J, Mathiaparanam J, Douglass A, Wolman MA, Sagasti A. PMID: 30204029; PMCID: PMC6464818.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    16. The Midline Axon Crossing Decision Is Regulated through an Activity-Dependent Mechanism by the NMDA Receptor. eNeuro. 2018 Mar-Apr; 5(2). Gao J, Stevenson TJ, Douglass AD, Barrios JP, Bonkowsky JL. PMID: 29766040; PMCID: PMC5952305.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    17. Motor Behavior Mediated by Continuously Generated Dopaminergic Neurons in the Zebrafish Hypothalamus Recovers after Cell Ablation. Curr Biol. 2016 Jan 25; 26(2):263-269. McPherson AD, Barrios JP, Luks-Morgan SJ, Manfredi JP, Bonkowsky JL, Douglass AD, Dorsky RI. PMID: 26774784; PMCID: PMC4864152.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    18. Transgenic FingRs for Live Mapping of Synaptic Dynamics in Genetically-Defined Neurons. Sci Rep. 2016 Jan 05; 6:18734. Son JH, Keefe MD, Stevenson TJ, Barrios JP, Anjewierden S, Newton JB, Douglass AD, Bonkowsky JL. PMID: 26728131; PMCID: PMC4700522.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    19. Chromatin insulator bodies are nuclear structures that form in response to osmotic stress and cell death. J Cell Biol. 2013 Jul 22; 202(2):261-76. Schoborg T, Rickels R, Barrios J, Labrador M. PMID: 23878275; PMCID: PMC3718971.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
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