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Mark Pletcher, MD, MPH

TitleProfessor
SchoolUCSF School of Medicine
DepartmentEpidemiology & Biostatistics
Address550 16th. Street
San Francisco CA 94158
Phone415-514-8008
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    Collapse Biography 
    Collapse Education and Training
    University of California, San Francisco Residency School of Medicine
    University of California, San FranciscoM.D.1998School of Medicine

    Collapse Overview 
    Collapse Overview
    As an epidemiologist and a general internal medicine physician, my research is designed to inform clinical decision-making and policy relevant to primary care and prevention. I focus on prevention of cardiovascular disease, and have particular interests in early life causes of atherosclerosis, primordial and primary coronary heart disease and stroke prevention, clinical decision-making regarding use of preventive medications (statins and anti-hypertensive medications) and screening for subclinical cardiovascular disease. I have special expertise in study design, decision and cost-effectiveness analysis, risk prediction, and evaluating the clinical utility of biomarkers, and I currently lead a data coordinating center for a major ongoing multicenter clinical trial, the Health eHeart Study (an online technology-enabled cardiovascular cohort study), and the Health eHeart Alliance, a PCORI-funded Patient-Powered Research Network focused on heart health. My primary appointment is in the Department of Epidemiology and Biostatistics at UCSF, and I see patients in General Internal Medicine at UCSF/Mt. Zion. I also help lead our nationally-recognized clinical research training programs, teach clinical research methods (Course Director for 2 classes), mentor students, fellows and junior faculty members, and direct the UCSF CTSI’s Informatics and Research Innovation Program.


    Collapse Research 
    Collapse Research Activities and Funding
    The Health ePeople Resource for Mobilized Research
    NIH/NIBIB U2CEB021881Sep 30, 2015 - Jul 31, 2020
    Role: Co-Principal Investigator
    An Economic Framework for Evaluating Biomarkers Used to Target CVD Prevention
    NIH/NHLBI R21HL112256Sep 21, 2011 - Jul 31, 2014
    Role: Principal Investigator
    Data Coordinating Center for VEST and PREDICTS
    NIH/NHLBI U01HL089145Sep 1, 2007 - May 31, 2012
    Role: Principal Investigator
    Opioid Prescribing Patterns in the U.S.
    AHRQ R03HS016238Mar 1, 2006 - Feb 28, 2009
    Role: Principal Investigator
    Serum Protemic Patterns Associated With Atherosclerosis
    NIH/NHLBI R21HL079276Jan 1, 2005 - Sep 30, 2008
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Websites
    Collapse In The News
    Collapse Global Health

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Guo X, Vittinghoff E, Vedantham V, Pletcher M, Lee BK. Trends in Hospitalizations for Cardiac Sarcoidosis in the United States, 2005-2011. Circ J. 2017 Sep 13. PMID: 28904267.
      View in: PubMed
    2. Ishida JH, Auer R, Vittinghoff E, Pletcher M, Reis JP, Sidney S, Johansen KL, Bibbins-Domingo K, Peralta CA, Shlipak MG. Marijuana Use and Estimated Glomerular Filtration Rate in Young Adults. Clin J Am Soc Nephrol. 2017 Aug 24. PMID: 28838990.
      View in: PubMed
    3. Heller DJ, Coxson PG, Penko J, Pletcher M, Goldman L, Odden MC, Kazi DS, Bibbins-Domingo K. Evaluating the Impact and Cost-Effectiveness of Statin Use Guidelines for Primary Prevention of Coronary Heart Disease and Stroke. Circulation. 2017 Sep 19; 136(12):1087-1098. PMID: 28687710.
      View in: PubMed
    4. Gelfand AA, Qubty W, Patniyot I, Grimes B, Pletcher M, Goadsby PJ, Cummings SR. Home-Based Trials in Adolescent Migraine: A Randomized Clinical Trial. JAMA Neurol. 2017 Jun 01; 74(6):744-745. PMID: 28437521.
      View in: PubMed
    5. Guo X, Vittinghoff E, Olgin JE, Marcus GM, Pletcher M. Volunteer Participation in the Health eHeart Study: A Comparison with the US Population. Sci Rep. 2017 May 16; 7(1):1956. PMID: 28512303.
      View in: PubMed
    6. Kramer H, Colangelo L, Lewis CE, Jacobs DR, Pletcher M, Bibbins-Domingo K, Chang A, Siscovick D, Shlipak M, Peralta CA, Bansal N, Muntner P, Liu K. Cumulative Exposure to Systolic Blood Pressure During Young Adulthood Through Midlife and the Urine Albumin-to-Creatinine Ratio at Midlife. Am J Hypertens. 2017 May 01; 30(5):502-509. PMID: 28338726.
      View in: PubMed
    7. Pletcher M, McCulloch CE. The Challenges of Generating Evidence to Support Precision Medicine. JAMA Intern Med. 2017 Apr 01; 177(4):561-562. PMID: 28192561.
      View in: PubMed
    8. Nguyen KT, Olgin JE, Pletcher M, Ng M, Kaye L, Moturu S, Gladstone RA, Malladi C, Fann AH, Maguire C, Bettencourt L, Christensen MA, Marcus GM. Smartphone-Based Geofencing to Ascertain Hospitalizations. Circ Cardiovasc Qual Outcomes. 2017 Mar; 10(3). PMID: 28325751.
      View in: PubMed
    9. Reis JP, Auer R, Bancks MP, Goff DC, Lewis CE, Pletcher M, Rana JS, Shikany JM, Sidney S. Cumulative Lifetime Marijuana Use and Incident Cardiovascular Disease in Middle Age: The Coronary Artery Risk Development in Young Adults (CARDIA) Study. Am J Public Health. 2017 Apr; 107(4):601-606. PMID: 28207342.
      View in: PubMed
    10. Pletcher M, Pignone M, Jarmul JA, Moran AE, Vittinghoff E, Newman T. Population Impact & Efficiency of Benefit-Targeted Versus Risk-Targeted Statin Prescribing for Primary Prevention of Cardiovascular Disease. J Am Heart Assoc. 2017 Feb 10; 6(2). PMID: 28188251.
      View in: PubMed
    11. Block VJ, Lizée A, Crabtree-Hartman E, Bevan CJ, Graves JS, Bove R, Green AJ, Nourbakhsh B, Tremblay M, Gourraud PA, Ng MY, Pletcher M, Olgin JE, Marcus GM, Allen DD, Cree BA, Gelfand JM. Continuous daily assessment of multiple sclerosis disability using remote step count monitoring. J Neurol. 2017 Feb; 264(2):316-326. PMID: 27896433.
      View in: PubMed
    12. Christensen MA, Bettencourt L, Kaye L, Moturu ST, Nguyen KT, Olgin JE, Pletcher M, Marcus GM. Direct Measurements of Smartphone Screen-Time: Relationships with Demographics and Sleep. PLoS One. 2016; 11(11):e0165331. PMID: 27829040.
      View in: PubMed
    13. Jones WS, Roe MT, Antman EM, Pletcher M, Harrington RA, Rothman RL, Oetgen WJ, Rao SV, Krucoff MW, Curtis LH, Hernandez AF, Masoudi FA. The Changing Landscape of Randomized Clinical Trials in Cardiovascular Disease. J Am Coll Cardiol. 2016 Oct 25; 68(17):1898-1907. PMID: 27765193.
      View in: PubMed
    14. Newman TB, Schroeder AR, Pletcher M. Lipid Screening in Children: Low-Value Care. JAMA Intern Med. 2016 Oct 01; 176(10):1437-1438. PMID: 27533131.
      View in: PubMed
    15. Guo X, Li Z, Guo L, Yu S, Li T, Zheng L, Pan G, Yang J, Sun Y, Hui R, Pletcher M. Prevalence of hypokinetic non-dilated cardiomyopathy in a large general Chinese population. Int J Cardiol. 2016 Nov 15; 223:708-710. PMID: 27573592.
      View in: PubMed
    16. Dukes JW, Dewland TA, Vittinghoff E, Olgin JE, Pletcher M, Hahn JA, Gladstone RA, Marcus GM. Access to alcohol and heart disease among patients in hospital: observational cohort study using differences in alcohol sales laws. BMJ. 2016 Jun 14; 353:i2714. PMID: 27301557; PMCID: PMC4908314.
    17. Pletcher M, Vittinghoff E, Thanataveerat A, Bibbins-Domingo K, Moran AE. Young Adult Exposure to Cardiovascular Risk Factors and Risk of Events Later in Life: The Framingham Offspring Study. PLoS One. 2016; 11(5):e0154288. PMID: 27138014; PMCID: PMC4854462.
    18. Brooks GC, Lee BK, Rao R, Lin F, Morin DP, Zweibel SL, Buxton AE, Pletcher M, Vittinghoff E, Olgin JE. Predicting Persistent Left Ventricular Dysfunction Following Myocardial Infarction: The PREDICTS Study. J Am Coll Cardiol. 2016 Mar 15; 67(10):1186-1196. PMID: 26965540; PMCID: PMC4854198 [Available on 03/15/17].
    19. Auer R, Vittinghoff E, Yaffe K, Künzi A, Kertesz SG, Levine DA, Albanese E, Whitmer RA, Jacobs DR, Sidney S, Glymour MM, Pletcher M. Association Between Lifetime Marijuana Use and Cognitive Function in Middle Age: The Coronary Artery Risk Development in Young Adults (CARDIA) Study. JAMA Intern Med. 2016 Mar; 176(3):352-61. PMID: 26831916.
      View in: PubMed
    20. Miedema MD, Petrone A, Shikany JM, Greenland P, Lewis CE, Pletcher M, Gaziano JM, Djousse L. Association of Fruit and Vegetable Consumption During Early Adulthood With the Prevalence of Coronary Artery Calcium After 20 Years of Follow-Up: The Coronary Artery Risk Development in Young Adults (CARDIA) Study. Circulation. 2015 Nov 24; 132(21):1990-8. PMID: 26503880; PMCID: PMC4659718 [Available on 11/24/16].
    21. Liu K, Colangelo LA, Daviglus ML, Goff DC, Pletcher M, Schreiner PJ, Sibley CT, Burke GL, Post WS, Michos ED, Lloyd-Jones DM. Can Antihypertensive Treatment Restore the Risk of Cardiovascular Disease to Ideal Levels?: The Coronary Artery Risk Development in Young Adults (CARDIA) Study and the Multi-Ethnic Study of Atherosclerosis (MESA). J Am Heart Assoc. 2015 Sep 21; 4(9):e002275. PMID: 26391135; PMCID: PMC4599509.
    22. Pletcher M. Treating elevated LDL cholesterol in patients with low short-term risk: Decision making at the limits of EBM. Evid Based Med. 2015 Oct; 20(5):151-3. PMID: 26378087.
      View in: PubMed
    23. Finkelstein JA, Brickman AL, Capron A, Ford DE, Gombosev A, Greene SM, Iafrate RP, Kolaczkowski L, Pallin SC, Pletcher M, Staman KL, Vazquez MA, Sugarman J. Oversight on the borderline: Quality improvement and pragmatic research. Clin Trials. 2015 Oct; 12(5):457-66. PMID: 26374685; PMCID: PMC4699562 [Available on 10/01/16].
    24. McKinney RE, Beskow LM, Ford DE, Lantos JD, McCall J, Patrick-Lake B, Pletcher M, Rath B, Schmidt H, Weinfurt K. Use of altered informed consent in pragmatic clinical research. Clin Trials. 2015 Oct; 12(5):494-502. PMID: 26374677; PMCID: PMC4688909.
    25. Bancks MP, Pletcher M, Kertesz SG, Sidney S, Rana JS, Schreiner PJ. Marijuana use and risk of prediabetes and diabetes by middle adulthood: the Coronary Artery Risk Development in Young Adults (CARDIA) study. Diabetologia. 2015 Dec; 58(12):2736-44. PMID: 26364621; PMCID: PMC4631659 [Available on 12/01/16].
    26. Dixit S, Pletcher M, Vittinghoff E, Imburgia K, Maguire C, Whitman IR, Glantz SA, Olgin JE, Marcus GM. Secondhand smoke and atrial fibrillation: Data from the Health eHeart Study. Heart Rhythm. 2016 Jan; 13(1):3-9. PMID: 26340844; PMCID: PMC4698178 [Available on 01/01/17].
    27. Jarmul JA, Pignone M, Pletcher M. Interpreting Hemoglobin A1C in Combination With Conventional Risk Factors for Prediction of Cardiovascular Risk. Circ Cardiovasc Qual Outcomes. 2015 Sep; 8(5):501-7. PMID: 26349840; PMCID: PMC4703493.
    28. Brooks GC, Vittinghoff E, Iyer S, Tandon D, Kuhar P, Madsen KA, Marcus GM, Pletcher M, Olgin JE. Accuracy and Usability of a Self-Administered 6-Minute Walk Test Smartphone Application. Circ Heart Fail. 2015 Sep; 8(5):905-13. PMID: 26283292; PMCID: PMC4843495.
    29. Gunderson EP, Quesenberry CP, Ning X, Jacobs DR, Gross M, Goff DC, Pletcher M, Lewis CE. Lactation Duration and Midlife Atherosclerosis. Obstet Gynecol. 2015 Aug; 126(2):381-90. PMID: 26241429.
      View in: PubMed
    30. Whitman IR, Pletcher M, Vittinghoff E, Imburgia KE, Maguire C, Bettencourt L, Sinha T, Parsnick T, Tison GH, Mulvanny CG, Olgin JE, Marcus GM. Perceptions, Information Sources, and Behavior Regarding Alcohol and Heart Health. Am J Cardiol. 2015 Aug 15; 116(4):642-6. PMID: 26092272; PMCID: PMC4522219.
    31. Douglas MP, Ladabaum U, Pletcher M, Marshall DA, Phillips KA. Economic evidence on identifying clinically actionable findings with whole-genome sequencing: a scoping review. Genet Med. 2016 Feb; 18(2):111-6. PMID: 25996638; PMCID: PMC4654986.
    32. Odden MC, Pletcher M, Coxson PG, Thekkethala D, Guzman D, Heller D, Goldman L, Bibbins-Domingo K. Cost-effectiveness and population impact of statins for primary prevention in adults aged 75 years or older in the United States. Ann Intern Med. 2015 Apr 21; 162(8):533-41. PMID: 25894023; PMCID: PMC4476404.
    33. Phillips KA, Ladabaum U, Pletcher M, Marshall DA, Douglas MP. Key emerging themes for assessing the cost-effectiveness of reporting incidental findings. Genet Med. 2015 Apr; 17(4):314-5. PMID: 25835195; PMCID: PMC4395812.
    34. Fontil V, Bibbins-Domingo K, Kazi DS, Sidney S, Coxson PG, Khanna R, Victor RG, Pletcher M. Simulating Strategies for Improving Control of Hypertension Among Patients with Usual Source of Care in the United States: The Blood Pressure Control Model. J Gen Intern Med. 2015 Aug; 30(8):1147-55. PMID: 25749880; PMCID: PMC4510247.
    35. Pletcher M, Lo B, Grady D. Criteria for waiver of informed consent for quality improvement research-reply. JAMA Intern Med. 2015 Jan; 175(1):143. PMID: 25560949.
      View in: PubMed
    36. Phillips KA, Pletcher M, Ladabaum U. Is the ``$1000 Genome'' really $1000? Understanding the full benefits and costs of genomic sequencing. Technol Health Care. 2015; 23(3):373-9. PMID: 25669213; PMCID: PMC4527943.
    37. Phillips KA, Trosman JR, Kelley RK, Pletcher M, Douglas MP, Weldon CB. Genomic sequencing: assessing the health care system, policy, and big-data implications. Health Aff (Millwood). 2014 Jul; 33(7):1246-53. PMID: 25006153; PMCID: PMC4113721.
    38. Auer R, Vittinghoff E, Kiefe C, Reis JP, Rodondi N, Khodneva YA, Kertesz SG, Cornuz J, Pletcher M. Change in physical activity after smoking cessation: the Coronary Artery Risk Development in Young Adults (CARDIA) study. Addiction. 2014 Jul; 109(7):1172-83. PMID: 24690003; PMCID: PMC4088346.
    39. Pletcher M, Lo B, Grady D. Informed consent in randomized quality improvement trials: a critical barrier for learning health systems. JAMA Intern Med. 2014 May; 174(5):668-70. PMID: 24615554.
      View in: PubMed
    40. Yaffe K, Vittinghoff E, Pletcher M, Hoang TD, Launer LJ, Whitmer R, Coker LH, Sidney S. Early adult to midlife cardiovascular risk factors and cognitive function. Circulation. 2014 Apr 15; 129(15):1560-7. PMID: 24687777; PMCID: PMC4700881.
    41. Gunderson EP, Chiang V, Pletcher M, Jacobs DR, Quesenberry CP, Sidney S, Lewis CE. History of gestational diabetes mellitus and future risk of atherosclerosis in mid-life: the Coronary Artery Risk Development in Young Adults study. J Am Heart Assoc. 2014 Mar 12; 3(2):e000490. PMID: 24622610; PMCID: PMC4187501.
    42. Pletcher M, Pignone M, Earnshaw S, McDade C, Phillips KA, Auer R, Zablotska L, Greenland P. Using the coronary artery calcium score to guide statin therapy: a cost-effectiveness analysis. Circ Cardiovasc Qual Outcomes. 2014 Mar; 7(2):276-84. PMID: 24619318; PMCID: PMC4156513.
    43. Fontil V, Pletcher M, Khanna R, Guzman D, Victor R, Bibbins-Domingo K. Physician underutilization of effective medications for resistant hypertension at office visits in the United States: NAMCS 2006-2010. J Gen Intern Med. 2014 Mar; 29(3):468-76. PMID: 24249113; PMCID: PMC3930772.
    44. Grewal SK, Haas AF, Pletcher M, Resneck JS. Compliance by California tanning facilities with the nation's first statewide ban on use before the age of 18 years. J Am Acad Dermatol. 2013 Dec; 69(6):883-889.e4. PMID: 24120564.
      View in: PubMed
    45. Shin J, Pletcher M. Risk of emergent bradycardia associated with the use of carvedilol and metoprolol in routine clinical practice. Am J Med. 2013 Sep; 126(9):805-810.e5. PMID: 23968902.
      View in: PubMed
    46. Raynor LA, Schreiner PJ, Loria CM, Carr JJ, Pletcher M, Shikany JM. Associations of retrospective and concurrent lipid levels with subclinical atherosclerosis prediction after 20 years of follow-up: the Coronary Artery Risk Development in Young Adults (CARDIA) study. Ann Epidemiol. 2013 Aug; 23(8):492-7. PMID: 23889858.
      View in: PubMed
    47. Pletcher M, Sibley CT, Pignone M, Vittinghoff E, Greenland P. Interpretation of the coronary artery calcium score in combination with conventional cardiovascular risk factors: the Multi-Ethnic Study of Atherosclerosis (MESA). Circulation. 2013 Sep 03; 128(10):1076-84. PMID: 23884352; PMCID: PMC3840900.
    48. Shin J, Gonzales M, Pletcher M. Risk of emergent bradycardia associated with initiation of immediate- or slow-release metoprolol. Pharmacotherapy. 2013 Dec; 33(12):1353-61. PMID: 23813768; PMCID: PMC3797244.
    49. Pignone M, Earnshaw S, McDade C, Pletcher M. Effect of including cancer mortality on the cost-effectiveness of aspirin for primary prevention in men. J Gen Intern Med. 2013 Nov; 28(11):1483-91. PMID: 23681842; PMCID: PMC3797356.
    50. Zeki Al Hazzouri A, Haan MN, Neuhaus JM, Pletcher M, Peralta CA, López L, Pérez Stable EJ. Cardiovascular risk score, cognitive decline, and dementia in older Mexican Americans: the role of sex and education. J Am Heart Assoc. 2013 Apr 22; 2(2):e004978. PMID: 23608609; PMCID: PMC3647277.
    51. Newman TB, Pletcher M, Hulley SB. Re: Childhood lipid screening: evidence and conflicts. Pediatrics. 2013 Apr; 131(4):e1385-6. PMID: 23547043.
      View in: PubMed
    52. Khanna RR, Victor RG, Bibbins-Domingo K, Shapiro MF, Pletcher M. Missed opportunities for treatment of uncontrolled hypertension at physician office visits in the United States, 2005 through 2009. Arch Intern Med. 2012 Sep 24; 172(17):1344-5. PMID: 22869238.
      View in: PubMed
    53. Newman TB, Pletcher M, Hulley SB. Overly aggressive new guidelines for lipid screening in children: evidence of a broken process. Pediatrics. 2012 Aug; 130(2):349-52. PMID: 22826571.
      View in: PubMed
    54. He H, Zhao Z, Chen J, Ni Y, Zhong J, Yan Z, Li Y, Liu D, Pletcher M, Zhu Z. Metformin-based treatment for obesity-related hypertension: a randomized, double-blind, placebo-controlled trial. J Hypertens. 2012 Jul; 30(7):1430-9. PMID: 22525206.
      View in: PubMed
    55. Viera AJ, Lin FC, Hinderliter AL, Shimbo D, Person SD, Pletcher M, Jacobs DR. Nighttime blood pressure dipping in young adults and coronary artery calcium 10-15 years later: the coronary artery risk development in young adults study. Hypertension. 2012 Jun; 59(6):1157-63. PMID: 22547435; PMCID: PMC3369268.
    56. Rodondi N, Locatelli I, Aujesky D, Butler J, Vittinghoff E, Simonsick E, Satterfield S, Newman AB, Wilson PW, Pletcher M, Bauer DC. Framingham risk score and alternatives for prediction of coronary heart disease in older adults. PLoS One. 2012; 7(3):e34287. PMID: 22470551; PMCID: PMC3314613.
    57. Kertesz SG, Khodneva Y, Richman J, Tucker JA, Safford MM, Jones B, Schumacher J, Pletcher M. Trajectories of drug use and mortality outcomes among adults followed over 18 years. J Gen Intern Med. 2012 Jul; 27(7):808-16. PMID: 22274889; PMCID: PMC3378735.
    58. Pletcher M, Vittinghoff E, Kalhan R, Richman J, Safford M, Sidney S, Lin F, Kertesz S. Association between marijuana exposure and pulmonary function over 20 years. JAMA. 2012 Jan 11; 307(2):173-81. PMID: 22235088; PMCID: PMC3840897.
    59. Galper BZ, Moran A, Coxson PG, Pletcher M, Heidenreich P, Lazar LD, Rodondi N, Wang YC, Goldman L. Using stress testing to guide primary prevention of coronary heart disease among intermediate-risk patients: a cost-effectiveness analysis. Circulation. 2012 Jan 17; 125(2):260-70. PMID: 22144567; PMCID: PMC3265963.
    60. Bibbins-Domingo K, Pletcher M. Blood pressure matters, even during young adulthood. J Am Coll Cardiol. 2011 Nov 29; 58(23):2404-5. PMID: 22115647.
      View in: PubMed
    61. Hamidovic A, Goodloe RJ, Bergen AW, Benowitz NL, Styn MA, Kasberger JL, Choquet H, Young TR, Meng Y, Palmer C, Pletcher M, Kertesz S, Hitsman B, Spring B, Jorgenson E. Gene-centric analysis of serum cotinine levels in African and European American populations. Neuropsychopharmacology. 2012 Mar; 37(4):968-74. PMID: 22089314; PMCID: PMC3280653.
    62. Kroenke CH, Pletcher M, Lin J, Blackburn E, Adler N, Matthews K, Epel E. Telomerase, telomere length, and coronary artery calcium in black and white men in the CARDIA study. Atherosclerosis. 2012 Feb; 220(2):506-12. PMID: 22178426.
      View in: PubMed
    63. Eisenberg ML, Park Y, Hollenbeck AR, Lipshultz LI, Schatzkin A, Pletcher M. Fatherhood and the risk of cardiovascular mortality in the NIH-AARP Diet and Health Study. Hum Reprod. 2011 Dec; 26(12):3479-85. PMID: 21946940; PMCID: PMC3212876.
    64. Pletcher M. Cardiovascular risk stratification, hemoglobin a1c, and the tempo of translation: comment on "Cardiovascular risk prediction in diabetic men and women using hemoglobin A1c vs diabetes as a high-risk equivalent". Arch Intern Med. 2011 Oct 24; 171(19):1718-20. PMID: 21788536.
      View in: PubMed
    65. Lazar LD, Pletcher M, Coxson PG, Bibbins-Domingo K, Goldman L. Cost-effectiveness of statin therapy for primary prevention in a low-cost statin era. Circulation. 2011 Jul 12; 124(2):146-53. PMID: 21709063.
      View in: PubMed
    66. Pletcher M, Pignone M. Evaluating the clinical utility of a biomarker: a review of methods for estimating health impact. Circulation. 2011 Mar 15; 123(10):1116-24. PMID: 21403122; PMCID: PMC3138723.
    67. Gillum LA, Gouveia C, Dorsey ER, Pletcher M, Mathers CD, McCulloch CE, Johnston SC. NIH disease funding levels and burden of disease. PLoS One. 2011 02 24; 6(2):e16837. PMID: 21383981; PMCID: PMC3044706.
    68. Simon LJ, Bizamcer AN, Lidz CW, Stefan S, Pletcher M. Disparities in opioid prescribing for patients with psychiatric diagnoses presenting with pain to the emergency department. Emerg Med J. 2012 Mar; 29(3):201-4. PMID: 21335578.
      View in: PubMed
    69. Reiner AP, Kahn A, Eisner BH, Pletcher M, Sadetsky N, Williams OD, Polak JF, Jacobs DR, Stoller ML. Kidney stones and subclinical atherosclerosis in young adults: the CARDIA study. J Urol. 2011 Mar; 185(3):920-5. PMID: 21251678; PMCID: PMC3827917.
    70. Nanchen D, Pletcher M, Cornuz J, Marques-Vidal PM, Paccaud F, Waeber G, Vollenweider P, Rodondi N. Public health impact of statin prescribing strategies based on JUPITER. Prev Med. 2011 Feb; 52(2):159-63. PMID: 21130802.
      View in: PubMed
    71. Foulds J, Hooper MW, Pletcher M, Okuyemi KS. Do smokers of menthol cigarettes find it harder to quit smoking? Nicotine Tob Res. 2010 Dec; 12 Suppl 2:S102-9. PMID: 21177366; PMCID: PMC3145377.
    72. Victor RG, Ravenell JE, Freeman A, Leonard D, Bhat DG, Shafiq M, Knowles P, Storm JS, Adhikari E, Bibbins-Domingo K, Coxson PG, Pletcher M, Hannan P, Haley RW. Effectiveness of a barber-based intervention for improving hypertension control in black men: the BARBER-1 study: a cluster randomized trial. Arch Intern Med. 2011 Feb 28; 171(4):342-50. PMID: 20975012; PMCID: PMC3365537.
    73. Pletcher M, Hulley SB. Statin therapy in young adults: ready for prime time? J Am Coll Cardiol. 2010 Aug 17; 56(8):637-40. PMID: 20705221.
      View in: PubMed
    74. Pletcher M, Bibbins-Domingo K, Liu K, Sidney S, Lin F, Vittinghoff E, Hulley SB. Nonoptimal lipids commonly present in young adults and coronary calcium later in life: the CARDIA (Coronary Artery Risk Development in Young Adults) study. Ann Intern Med. 2010 Aug 03; 153(3):137-46. PMID: 20679558; PMCID: PMC3468943.
    75. Friedlander Y, Li G, Fornage M, Williams OD, Lewis CE, Schreiner P, Pletcher M, Enquobahrie D, Williams M, Siscovick DS. Candidate molecular pathway genes related to appetite regulatory neural network, adipocyte homeostasis and obesity: results from the CARDIA Study. Ann Hum Genet. 2010 Sep 01; 74(5):387-98. PMID: 20642810; PMCID: PMC2945878.
    76. Flower K, Post A, Sussman J, Tangherlini N, Mendelson J, Pletcher M. Validation of triage criteria for deciding which apparently inebriated persons require emergency department care. Emerg Med J. 2011 Jul; 28(7):579-84. PMID: 20616108; PMCID: PMC4687738.
    77. Pletcher M, Coxson PG. Does age modify effectiveness of statin therapy in coronary artery disease? Ann Intern Med. 2010 Jun 15; 152(12):825; author reply 825-6. PMID: 20547915.
      View in: PubMed
    78. Tangherlini N, Pletcher M, Covec MA, Brown JF. Frequent use of emergency medical services by the elderly: a case-control study using paramedic records. Prehosp Disaster Med. 2010 May-Jun; 25(3):258-64. PMID: 20586020.
      View in: PubMed
    79. Pletcher M, Tice JA, Pignone M. Modeling cardiovascular disease prevention. JAMA. 2010 Mar 03; 303(9):835; author reply 835. PMID: 20197528.
      View in: PubMed
    80. Halanych JH, Safford MM, Kertesz SG, Pletcher M, Kim YI, Person SD, Lewis CE, Kiefe CI. Alcohol consumption in young adults and incident hypertension: 20-year follow-up from the Coronary Artery Risk Development in Young Adults Study. Am J Epidemiol. 2010 Mar 01; 171(5):532-9. PMID: 20118194; PMCID: PMC2842215.
    81. Bibbins-Domingo K, Chertow GM, Coxson PG, Moran A, Lightwood JM, Pletcher M, Goldman L. Projected effect of dietary salt reductions on future cardiovascular disease. N Engl J Med. 2010 Feb 18; 362(7):590-9. PMID: 20089957; PMCID: PMC3066566.
    82. Newman TB, Pletcher M. Coronary calcium screening. N Engl J Med. 2009 Dec 17; 361(25):2491; author reply 2491-2. PMID: 20050217.
      View in: PubMed
    83. Wang EA, Pletcher M, Lin F, Vittinghoff E, Kertesz SG, Kiefe CI, Bibbins-Domingo K. Incarceration, incident hypertension, and access to health care: findings from the coronary artery risk development in young adults (CARDIA) study. Arch Intern Med. 2009 Apr 13; 169(7):687-93. PMID: 19364998; PMCID: PMC2829673.
    84. Bibbins-Domingo K, Pletcher M, Lin F, Vittinghoff E, Gardin JM, Arynchyn A, Lewis CE, Williams OD, Hulley SB. Racial differences in incident heart failure among young adults. N Engl J Med. 2009 Mar 19; 360(12):1179-90. PMID: 19297571; PMCID: PMC2829671.
    85. Pletcher M, Lazar L, Bibbins-Domingo K, Moran A, Rodondi N, Coxson P, Lightwood J, Williams L, Goldman L. Comparing impact and cost-effectiveness of primary prevention strategies for lipid-lowering. Ann Intern Med. 2009 Feb 17; 150(4):243-54. PMID: 19221376.
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    86. Epel ES, Merkin SS, Cawthon R, Blackburn EH, Adler NE, Pletcher M, Seeman TE. The rate of leukocyte telomere shortening predicts mortality from cardiovascular disease in elderly men. Aging (Albany NY). 2008 Dec 04; 1(1):81-8. PMID: 20195384; PMCID: PMC2830080.
    87. Mendelson J, Flower K, Pletcher M, Galloway GP. Addiction to prescription opioids: characteristics of the emerging epidemic and treatment with buprenorphine. Exp Clin Psychopharmacol. 2008 Oct; 16(5):435-41. PMID: 18837640; PMCID: PMC4687728.
    88. Pletcher M, Bibbins-Domingo K, Lewis CE, Wei GS, Sidney S, Carr JJ, Vittinghoff E, McCulloch CE, Hulley SB. Prehypertension during young adulthood and coronary calcium later in life. Ann Intern Med. 2008 Jul 15; 149(2):91-9. PMID: 18626048; PMCID: PMC2587255.
    89. Pletcher M, Greenland P. Coronary calcium scoring and cardiovascular risk: the SHAPE of things to come. Arch Intern Med. 2008 May 26; 168(10):1027-8. PMID: 18504328.
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    90. Pletcher M, Kertesz SG, Kohn MA, Gonzales R. Trends in opioid prescribing by race/ethnicity for patients seeking care in US emergency departments. JAMA. 2008 Jan 02; 299(1):70-8. PMID: 18167408.
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    91. Bibbins-Domingo K, Coxson P, Pletcher M, Lightwood J, Goldman L. Adolescent overweight and future adult coronary heart disease. N Engl J Med. 2007 Dec 06; 357(23):2371-9. PMID: 18057339.
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    92. Costanzo PR, Malone PS, Belsky D, Kertesz S, Pletcher M, Sloan FA. Longitudinal differences in alcohol use in early adulthood. J Stud Alcohol Drugs. 2007 Sep; 68(5):727-37. PMID: 17690807.
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    93. Resneck JS, Lipton S, Pletcher M. Short wait times for patients seeking cosmetic botulinum toxin appointments with dermatologists. J Am Acad Dermatol. 2007 Dec; 57(6):985-9. PMID: 17720277.
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    94. Borrell LN, Jacobs DR, Williams DR, Pletcher M, Houston TK, Kiefe CI. Self-reported racial discrimination and substance use in the Coronary Artery Risk Development in Adults Study. Am J Epidemiol. 2007 Nov 01; 166(9):1068-79. PMID: 17698506.
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    95. Pignone M, Earnshaw S, Pletcher M, Tice JA. Aspirin for the primary prevention of cardiovascular disease in women: a cost-utility analysis. Arch Intern Med. 2007 Feb 12; 167(3):290-5. PMID: 17296886.
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    96. Kertesz SG, Pletcher M, Safford M, Halanych J, Kirk K, Schumacher J, Sidney S, Kiefe CI. Illicit drug use in young adults and subsequent decline in general health: the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Drug Alcohol Depend. 2007 May 11; 88(2-3):224-33. PMID: 17137732; PMCID: PMC1885466.
    97. Pletcher M, Hulley BJ, Houston T, Kiefe CI, Benowitz N, Sidney S. Menthol cigarettes, smoking cessation, atherosclerosis, and pulmonary function: the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Arch Intern Med. 2006 Sep 25; 166(17):1915-22. PMID: 17000950.
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    98. Pletcher M. What about other causes of death? Arch Intern Med. 2006 Jul 24; 166(14):1528; author reply 1528-9. PMID: 16864768.
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    99. Rodondi N, Pletcher M, Liu K, Hulley SB, Sidney S. Marijuana use, diet, body mass index, and cardiovascular risk factors (from the CARDIA study). Am J Cardiol. 2006 Aug 15; 98(4):478-84. PMID: 16893701.
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    100. Pletcher M, Kertesz SG, Sidney S, Kiefe CI, Hulley SB. Incidence and antecedents of nonmedical prescription opioid use in four US communities. The Coronary Artery Risk Development in Young Adults (CARDIA) prospective cohort study. Drug Alcohol Depend. 2006 Nov 08; 85(2):171-6. PMID: 16723193.
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    101. Houston TK, Person SD, Pletcher M, Liu K, Iribarren C, Kiefe CI. Active and passive smoking and development of glucose intolerance among young adults in a prospective cohort: CARDIA study. BMJ. 2006 May 06; 332(7549):1064-9. PMID: 16603565; PMCID: PMC1458534.
    102. Pignone M, Earnshaw S, Tice JA, Pletcher M. Aspirin, statins, or both drugs for the primary prevention of coronary heart disease events in men: a cost-utility analysis. Ann Intern Med. 2006 Mar 07; 144(5):326-36. PMID: 16520473.
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    103. Hozawa A, Houston T, Steffes MW, Widome R, Williams OD, Iribarren C, Pletcher M, Daviglus ML, Carr JJ, Jacobs DR. The association of cigarette smoking with self-reported disease before middle age: the Coronary Artery Risk Development in Young Adults (CARDIA) study. Prev Med. 2006 Mar; 42(3):193-9. PMID: 16480762.
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    104. Sporer KA, Tabas JA, Tam RK, Sellers KL, Rosenson J, Barton CW, Pletcher M. Do medications affect vital signs in the prehospital treatment of acute decompensated heart failure? Prehosp Emerg Care. 2006 Jan-Mar; 10(1):41-5. PMID: 16418090.
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    105. Pletcher M, McCulloch C. Nomogram for exercise capacity in women. N Engl J Med. 2005 Nov 24; 353(21):2301-3; author reply 2301-3. PMID: 16312065.
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    106. Pletcher M, Kiefe CI, Sidney S, Carr JJ, Lewis CE, Hulley SB. Cocaine and coronary calcification in young adults: the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Am Heart J. 2005 Nov; 150(5):921-6. PMID: 16290964.
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    107. Tsui JI, Pletcher M, Vittinghoff E, Seal K, Gonzales R. Hepatitis C and hospital outcomes in patients admitted with alcohol-related problems. J Hepatol. 2006 Feb; 44(2):262-6. PMID: 16226823.
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    108. Pletcher M, Fernandez A, May TA, Westphal JR, Gamez CA, Hersh DF, Gonzales R. Unintended consequences of a quality improvement program designed to improve treatment of alcohol withdrawal in hospitalized patients. Jt Comm J Qual Patient Saf. 2005 Mar; 31(3):148-57. PMID: 15828598.
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    109. Pletcher M, Varosy P, Kiefe CI, Lewis CE, Sidney S, Hulley SB. Alcohol consumption, binge drinking, and early coronary calcification: findings from the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Am J Epidemiol. 2005 Mar 01; 161(5):423-33. PMID: 15718478.
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    110. Pletcher M, Maselli J, Gonzales R. Uncomplicated alcohol intoxication in the emergency department: an analysis of the National Hospital Ambulatory Medical Care Survey. Am J Med. 2004 Dec 01; 117(11):863-7. PMID: 15589492.
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    111. Resneck JS, Van Beek M, Furmanski L, Oyugi J, LeBoit PE, Katabira E, Kambugu F, Maurer T, Berger T, Pletcher M, Machtinger EL. Etiology of pruritic papular eruption with HIV infection in Uganda. JAMA. 2004 Dec 01; 292(21):2614-21. PMID: 15572719.
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    112. Pletcher M, Tice JA, Pignone M, McCulloch C, Callister TQ, Browner WS. What does my patient's coronary artery calcium score mean? Combining information from the coronary artery calcium score with information from conventional risk factors to estimate coronary heart disease risk. BMC Med. 2004 Aug 24; 2:31. PMID: 15327691; PMCID: PMC515311.
    113. Pletcher M, Tice JA, Pignone M, Browner WS. Using the coronary artery calcium score to predict coronary heart disease events: a systematic review and meta-analysis. Arch Intern Med. 2004 Jun 28; 164(12):1285-92. PMID: 15226161.
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    114. Pletcher M, Tice JA, Pignone M. Use of coronary calcification scores to predict coronary heart disease. JAMA. 2004 Apr 21; 291(15):1831-2; author reply 1832-3. PMID: 15100194.
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    115. Fowler-Brown A, Pignone M, Pletcher M, Tice JA, Sutton SF, Lohr KN. Exercise tolerance testing to screen for coronary heart disease: a systematic review for the technical support for the U.S. Preventive Services Task Force. Ann Intern Med. 2004 Apr 06; 140(7):W9-24. PMID: 15069009.
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    116. Resneck J, Pletcher M, Lozano N. Medicare, Medicaid, and access to dermatologists: the effect of patient insurance on appointment access and wait times. J Am Acad Dermatol. 2004 Jan; 50(1):85-92. PMID: 14699371.
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    117. Galil K, Pletcher M, Wallace BJ, Seward J, Meyer PA, Baughman AL, Wharton M. Tracking varicella deaths: accuracy and completeness of death certificates and hospital discharge records, New York State, 1989-1995. Am J Public Health. 2002 Aug; 92(8):1248-50. PMID: 12144978; PMCID: PMC1447224.
    118. Bloch KC, Zwerling L, Pletcher M, Hahn JA, Gerberding JL, Ostroff SM, Vugia DJ, Reingold AL. Incidence and clinical implications of isolation of Mycobacterium kansasii: results of a 5-year, population-based study. Ann Intern Med. 1998 Nov 01; 129(9):698-704. PMID: 9841601.
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