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Lamorna Swigart, PhD

Title(s)Associate Professor, Laboratory Medicine
SchoolSchool of Medicine
Address2340 Sutter Street
San Francisco CA 94115
Phone415-476-3461
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. MYC Instructs and Maintains Pancreatic Adenocarcinoma Phenotype. Cancer Discov. 2020 Apr; 10(4):588-607. Sodir NM, Kortlever RM, Barthet VJA, Campos T, Pellegrinet L, Kupczak S, Anastasiou P, Swigart LB, Soucek L, Arends MJ, Littlewood TD, Evan GI. PMID: 31941709.
      View in: PubMed   Mentions: 4     Fields:    
    2. Sall2 is required for proapoptotic Noxa expression and genotoxic stress-induced apoptosis by doxorubicin. Cell Death Dis. 2015 Jul 16; 6:e1816. Escobar D, Hepp MI, Farkas C, Campos T, Sodir NM, Morales M, Álvarez CI, Swigart L, Evan GI, Gutiérrez JL, Nishinakamura R, Castro AF, Pincheira R. PMID: 26181197.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    3. Myc inhibition is effective against glioma and reveals a role for Myc in proficient mitosis. Nat Commun. 2014 Aug 18; 5:4632. Annibali D, Whitfield JR, Favuzzi E, Jauset T, Serrano E, Cuartas I, Redondo-Campos S, Folch G, Gonzàlez-Juncà A, Sodir NM, Massó-Vallés D, Beaulieu ME, Swigart LB, Mc Gee MM, Somma MP, Nasi S, Seoane J, Evan GI, Soucek L. PMID: 25130259.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    4. Using a preclinical mouse model of high-grade astrocytoma to optimize p53 restoration therapy. Proc Natl Acad Sci U S A. 2013 Apr 16; 110(16):E1480-9. Shchors K, Persson AI, Rostker F, Tihan T, Lyubynska N, Li N, Swigart LB, Berger MS, Hanahan D, Weiss WA, Evan GI. PMID: 23542378.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    5. Inhibition of Myc family proteins eradicates KRas-driven lung cancer in mice. Genes Dev. 2013 Mar 01; 27(5):504-13. Soucek L, Whitfield JR, Sodir NM, Massó-Vallés D, Serrano E, Karnezis AN, Swigart LB, Evan GI. PMID: 23475959.
      View in: PubMed   Mentions: 106     Fields:    Translation:Animals
    6. Sequential Cdk1 and Plk1 phosphorylation of protein tyrosine phosphatase 1B promotes mitotic cell death. Cell Death Dis. 2013 Jan 24; 4:e468. O'Donovan DS, MacFhearraigh S, Whitfield J, Swigart LB, Evan GI, Mc Gee MM. PMID: 23348582.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    7. Role of c-MYC in alternative activation of human macrophages and tumor-associated macrophage biology. Blood. 2012 Jan 12; 119(2):411-21. Pello OM, De Pizzol M, Mirolo M, Soucek L, Zammataro L, Amabile A, Doni A, Nebuloni M, Swigart LB, Evan GI, Mantovani A, Locati M. PMID: 22067385.
      View in: PubMed   Mentions: 103     Fields:    Translation:HumansCells
    8. Modeling pharmacological inhibition of mast cell degranulation as a therapy for insulinoma. Neoplasia. 2011 Nov; 13(11):1093-100. Soucek L, Buggy JJ, Kortlever R, Adimoolam S, Monclús HA, Allende MT, Swigart LB, Evan GI. PMID: 22131884.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    9. Endogenous Myc maintains the tumor microenvironment. Genes Dev. 2011 May 01; 25(9):907-16. Sodir NM, Swigart LB, Karnezis AN, Hanahan D, Evan GI, Soucek L. PMID: 21478273.
      View in: PubMed   Mentions: 71     Fields:    Translation:AnimalsCells
    10. Acute overexpression of Myc in intestinal epithelium recapitulates some but not all the changes elicited by Wnt/beta-catenin pathway activation. Mol Cell Biol. 2009 Oct; 29(19):5306-15. Finch AJ, Soucek L, Junttila MR, Swigart LB, Evan GI. PMID: 19635809.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    11. Modelling Myc inhibition as a cancer therapy. Nature. 2008 Oct 02; 455(7213):679-83. Soucek L, Whitfield J, Martins CP, Finch AJ, Murphy DJ, Sodir NM, Karnezis AN, Swigart LB, Nasi S, Evan GI. PMID: 18716624.
      View in: PubMed   Mentions: 301     Fields:    Translation:Animals
    12. Regulated beta-cell regeneration in the adult mouse pancreas. Diabetes. 2008 Apr; 57(4):958-66. Cano DA, Rulifson IC, Heiser PW, Swigart LB, Pelengaris S, German M, Evan GI, Bluestone JA, Hebrok M. PMID: 18083786.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    13. Mast cells are required for angiogenesis and macroscopic expansion of Myc-induced pancreatic islet tumors. Nat Med. 2007 Oct; 13(10):1211-8. Soucek L, Lawlor ER, Soto D, Shchors K, Swigart LB, Evan GI. PMID: 17906636.
      View in: PubMed   Mentions: 164     Fields:    Translation:AnimalsCells
    14. Mdm2 is critically and continuously required to suppress lethal p53 activity in vivo. Cancer Cell. 2006 Dec; 10(6):501-14. Ringshausen I, O'Shea CC, Finch AJ, Swigart LB, Evan GI. PMID: 17157790.
      View in: PubMed   Mentions: 107     Fields:    Translation:AnimalsCells
    15. The pathological response to DNA damage does not contribute to p53-mediated tumour suppression. Nature. 2006 Sep 14; 443(7108):214-7. Christophorou MA, Ringshausen I, Finch AJ, Swigart LB, Evan GI. PMID: 16957739.
      View in: PubMed   Mentions: 162     Fields:    Translation:Animals
    16. Bcl-xL gain of function and p19 ARF loss of function cooperate oncogenically with Myc in vivo by distinct mechanisms. Cancer Cell. 2006 Aug; 10(2):113-20. Finch A, Prescott J, Shchors K, Hunt A, Soucek L, Dansen TB, Swigart LB, Evan GI. PMID: 16904610.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    17. Bid mediates apoptotic synergy between tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and DNA damage. J Biol Chem. 2005 Apr 01; 280(13):12486-93. Broaddus VC, Dansen TB, Abayasiriwardana KS, Wilson SM, Finch AJ, Swigart LB, Hunt AE, Evan GI. PMID: 15615731.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    18. Defining the temporal requirements for Myc in the progression and maintenance of skin neoplasia. Oncogene. 2004 Aug 05; 23(35):5923-30. Flores I, Murphy DJ, Swigart LB, Knies U, Evan GI. PMID: 15208685.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    19. Id2 is dispensable for Myc-induced epidermal neoplasia. Mol Cell Biol. 2004 Mar; 24(5):2083-90. Murphy DJ, Swigart LB, Israel MA, Evan GI. PMID: 14966287.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    20. c-Myc functionally cooperates with Bax to induce apoptosis. Mol Cell Biol. 2002 Sep; 22(17):6158-69. Juin P, Hunt A, Littlewood T, Griffiths B, Swigart LB, Korsmeyer S, Evan G. PMID: 12167710.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells