Elias Botvinick, MD

Title(s)Professor, Medicine
SchoolSchool of Medicine
Address505 Parnassus Avenue
San Francisco CA 94117
Phone415-353-3817
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    Collapse Biography 
    Collapse Education and Training
    University of California, San Francisco Clinical Fellowship School of Medicine
    University of California, San FranciscoResidency School of Medicine - Cardiology
    New York UniversityM.D.1967School of Medicine
    Collapse Awards and Honors
    Cardiology & Nuclear Medicine, San Francisco Magazine2000Best Doctor's in California
    American Society of Nuclear Cardiology1998Founding Member ASNC
    Graduation Nuclear Medicine Technology Training Program1994Keynote Speaker
    Society of Nuclear Medicine1992Founder and First President of the Cardiovascular Council
    University of California, San Francisco School of MedicineNominated for UCSF Medical School Kaiser award for Excellence in Teaching
    Society of Nuclear Medicine1991Recipient Herman H. Blumgart Lectureship Award
    United States Army1971Bronze Star Medal Award, Republic of Vietnam

    Collapse Overview 
    Collapse Overview
    Elias H. Botvinick, MD, is now retired and has been "called back". He now works 44% time, all devoted to clinical care, teaching and research in the Cardiovascular Division. Following is a summary of all affiliations, titles achieved, all, publications, funding, memberships and honors while actively working full-time in both the Cardiovascular division and the Nuclear Medicine Section of the Department of radiology.

    A Professor in Residence, Co-Director of the Adult Cardiology Non-Invasive Laboratory, and Director of the Cardiac Stress Testing Laboratory at the University of California, San Francisco. Dr. Botvinick received his medical degree from New York University School of Medicine in 1967, and completed a residency in Medicine at Bellevue Hospital in New York, followed by a fellowship in Nuclear Medicine from UCSF in 1976.

    Dr. Botvinick’s primary research interest has been scintigraphic methods. His research involves recent applications of the scintigraphic imaging agent indicates its ability to map the regional density of sympathetic nerves and support the hypothesis that an altered balance in the relationship of perfusion and innervation can increase vulnerability to life threatening arrhythmias. Overall, Dr. Botvinick’s research has been a collaborative effort to develop non-invasive graphic and imaging methods for the identification and evaluation of cardiac anatomy and pathophysiology, and apply them to the diagnosis, risk stratification and monitoring of clinical disease.

    Dr. Botvinick has written 178 articles, 46 book chapters, 301 abstracts, with 8 significant publications.

    Expertise:
    Nuclear Medicine and Cardiology

    Specialty:
    Nuclear cardiology, scintigraphy, cardiovascular diseases

    Professional Interests:
    Nuclear medicine, nuclear cardiology, PET/CT, MRI, CT, cardiac cardiology, echo cardiology, nuclear magnetic resonance, cardiovascular imaging, stress testing, heart, myocardial perfusion, scintigraphy, coronary, synchrony, synchronization

    Education and Training:
    • Medical School: New York University School of Medicine, New York
    • Internship: Bellevue Hospital, New York - Medicine
    • Internship: United States Army, Hospital, Fort Riley
    • Residency: Bellevue Hospital, New York - Medicine
    • Fellowship: University of California, San Francisco - Nuclear Medicine
    • New York State Medical License
    • Controlled Substance Registration Certificate
    • California State Medical
    • Internal Medicine Boards
    • Nuclear Medicine Boards
    • Cardiovascular Boards
    • Certified, Basic Cardiac Life Support
    • Certified, Advanced Cardiac Life Support

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    Collapse Academic Senate

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Assessment of late-term progression of cardiac allograft vasculopathy in patients with orthotopic heart transplantation using quantitative cardiac 82Rb PET. Int J Cardiovasc Imaging. 2021 Apr; 37(4):1461-1472. Shrestha UM, Sciammarella M, Pampaloni MH, Botvinick EH, Gullberg GT, DeMarco T, Seo Y. PMID: 33123937.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. The beginnings of ASNC. J Nucl Cardiol. 2019 Feb; 26(1):39-41. Botvinick EH. PMID: 30478663.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Comparison of sparse domain approaches for 4D SPECT dynamic image reconstruction. Med Phys. 2018 Oct; 45(10):4493-4509. Mitra D, Abdalah M, Boutchko R, Chang H, Shrestha U, Botvinick E, Seo Y, Gullberg GT. PMID: 30027577.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    4. A combined static-dynamic single-dose imaging protocol to compare quantitative dynamic SPECT with static conventional SPECT. J Nucl Cardiol. 2019 06; 26(3):763-771. Sciammarella M, Shrestha UM, Seo Y, Gullberg GT, Botvinick EH. PMID: 28776314.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    5. Noninvasive PET quantitative myocardial blood flow with regadenoson for assessing cardiac allograft vasculopathy in orthotopic heart transplantation patients. J Nucl Cardiol. 2017 08; 24(4):1134-1144. Pampaloni MH, Shrestha UM, Sciammarella M, Seo Y, Gullberg GT, Botvinick EH. PMID: 28138813.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    6. Utility of Equilibrium Radionuclide Angiogram-Derived Measures of Dyssynchrony to Predict Outcomes in Heart Failure Patients Undergoing Cardiac Resynchronization Therapy. J Nucl Med. 2016 Dec; 57(12):1880-1886. Badhwar N, James J, Hoffmayer KS, O'Connell JW, Green D, De Marco T, Botvinick EH. PMID: 27417646.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    7. Measurement of absolute myocardial blood flow in humans using dynamic cardiac SPECT and 99mTc-tetrofosmin: Method and validation. J Nucl Cardiol. 2017 02; 24(1):268-277. Shrestha U, Sciammarella M, Alhassen F, Yeghiazarians Y, Ellin J, Verdin E, Boyle A, Seo Y, Botvinick EH, Gullberg GT. PMID: 26715603.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    8. Image reconstruction in higher dimensions: myocardial perfusion imaging of tracer dynamics with cardiac motion due to deformation and respiration. Phys Med Biol. 2015 Nov 07; 60(21):8275-301. Shrestha UM, Seo Y, Botvinick EH, Gullberg GT. PMID: 26450115.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    9. Comparison of radionuclide angiographic synchrony analysis to echocardiography and magnetic resonance imaging for the diagnosis of arrhythmogenic right ventricular cardiomyopathy. Heart Rhythm. 2015 Jun; 12(6):1268-75. Johnson CJ, Roberts JD, James JH, Hoffmayer KS, Badhwar N, Ku IA, Zhao S, Naeger DM, Rao RK, O'Connell JW, De Marco T, Botvinick EH, Scheinman MM. PMID: 25744613.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    10. Erratum to: Isolated right ventricular cardiac sarcoidosis demonstrated by (18)FDG positron emission tomography. J Nucl Cardiol. 2015 Feb; 22(1):221. Pampaloni MH, Nazer B, Botvinick E. PMID: 25342216.
      View in: PubMed   Mentions:    Fields:    
    11. Quantitative Signature of Coronary Steal in a Patient with Occluded Coronary Arteries Supported by Collateral Circulation Using Dynamic SPECT. IEEE Nucl Sci Symp Conf Rec (1997). 2014 Nov; 2014. Shrestha U, Botvinick EH, Yeghiazarians Y, Seo Y, Gullberg GT. PMID: 27081301.
      View in: PubMed   Mentions:
    12. Isolated right ventricular cardiac sarcoidosis demonstrated by ¹8FDG positron emission tomography. J Nucl Cardiol. 2014 Jun; 21(3):652-4. Hernandez Pampaloni M, Nazer B, Nazar B, Botvinick E. PMID: 24429936.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    13. Imaging synchrony. J Nucl Cardiol. 2009 Nov-Dec; 16(6):846-8. Botvinick EH, O'Connell JW, Badhwar N. PMID: 19798545.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    14. The variable functional effects of the pacing site in normal and scarred ventricles. J Nucl Cardiol. 2009 Nov-Dec; 16(6):904-13. del Romeral LM, Stillson C, Lesh M, Botvinick E. PMID: 19760474.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    15. The relationship of myocardial contraction and electrical excitation--the correlation between scintigraphic phase image analysis and electrophysiologic mapping. J Nucl Cardiol. 2009 Sep-Oct; 16(5):792-800. del Romeral LM, Stillson C, Lesh M, Dae M, Botvinick E. PMID: 19636652.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    16. A pilot study of changes in (18)F-FDG uptake, calcification and global metabolic activity of the aorta with aging. Hell J Nucl Med. 2009 May-Aug; 12(2):123-8. Bural GG, Torigian DA, Botvinick E, Houseni M, Basu S, Chen W, Alavi A. PMID: 19675864.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    17. Current methods of pharmacologic stress testing and the potential advantages of new agents. J Nucl Med Technol. 2009 Mar; 37(1):14-25. Botvinick EH. PMID: 19258260.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    18. Localization of ventricular tachycardia exit site and subsequent contraction sequence and functional effects with bedside radionuclide angiography. JACC Cardiovasc Imaging. 2008 Sep; 1(5):605-13. Botvinick E, Davis J, Dae M, O'Connell J, Schechtmann N, Abbott J, Morady F, Lanzer P, Iskikian J, Scheinman M. PMID: 19356489.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    19. Age-related decrease in cardiopulmonary adrenergic neuronal function in children as assessed by I-123 metaiodobenzylguanidine imaging. J Nucl Cardiol. 2008 Jan-Feb; 15(1):73-9. Chen W, Botvinick EH, Alavi A, Zhang Y, Yang S, Perini R, Zhuang H. PMID: 18242482.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    20. Myocardial perfusion and function: single photon emission computed tomography. J Nucl Cardiol. 2007 Nov-Dec; 14(6):e39-60. Hansen CL, Goldstein RA, Akinboboye OO, Berman DS, Botvinick EH, Churchwell KB, Cooke CD, Corbett JR, Cullom SJ, Dahlberg ST, Druz RS, Ficaro EP, Galt JR, Garg RK, Germano G, Heller GV, Henzlova MJ, Hyun MC, Johnson LL, Mann A, McCallister BD, Quaife RA, Ruddy TD, Sundaram SN, Taillefer R, Ward RP, Mahmarian JJ, American Society of Nuclear Cardiology . PMID: 18022099.
      View in: PubMed   Mentions: 80     Fields:    Translation:Humans
    21. The aging of the heart and blood vessels: a consideration of anatomy and physiology in the era of computed tomography, magnetic resonance imaging, and positron emission tomographic imaging methods with special consideration of atherogenesis. Semin Nucl Med. 2007 Mar; 37(2):120-43. Botvinick EH, Perini R, Bural G, Chen W, Chryssikos T, Houseni M, Hernandez-Pampaloni M, Torigian DA, Alavi A. PMID: 17289459.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    22. Equilibrium radionuclide angiocardiography. J Nucl Cardiol. 2006 Nov; 13(6):e56-79. Corbett JR, Akinboboye OO, Bacharach SL, Borer JS, Botvinick EH, DePuey EG, Ficaro EP, Hansen CL, Henzlova MJ, Van Kriekinge S, Quality Assurance Committee of the American Society of Nuclear Cardiology . PMID: 17174797.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    23. A novel approach to multipinhole SPECT for myocardial perfusion imaging. J Nucl Med. 2006 Apr; 47(4):595-602. Funk T, Kirch DL, Koss JE, Botvinick E, Hasegawa BH. PMID: 16595492.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    24. A unique method by which to quantitate synchrony with equilibrium radionuclide angiography. J Nucl Cardiol. 2005 Jul-Aug; 12(4):441-50. O'Connell JW, Schreck C, Moles M, Badwar N, DeMarco T, Olgin J, Lee B, Tseng Z, Kumar U, Botvinick EH. PMID: 16084433.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCTClinical Trials
    25. Clinical value of attenuation correction in stress-only Tc-99m sestamibi SPECT imaging. J Nucl Cardiol. 2004 May-Jun; 11(3):273-81. Heller GV, Bateman TM, Johnson LL, Cullom SJ, Case JA, Galt JR, Garcia EV, Haddock K, Moutray KL, Poston C, Botvinick EH, Fish MB, Follansbee WP, Hayes S, Iskandrian AE, Mahmarian JJ, Vandecker W. PMID: 15173774.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansCTClinical Trials
    26. Increased right ventricular activity: artifact of camera head misalignment. J Nucl Cardiol. 2003 Sep-Oct; 10(5):575-6. Pham KH, Botvinick EH. PMID: 14569251.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    27. Scintigraphic blood pool and phase image analysis: the optimal tool for the evaluation of resynchronization therapy. J Nucl Cardiol. 2003 Jul-Aug; 10(4):424-8. Botvinick EH. PMID: 12900747.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    28. Unique contraction pattern in patients after coronary bypass graft surgery by gated SPECT myocardial perfusion imaging. Clin Nucl Med. 2003 Jan; 28(1):18-24. Yun JH, Block M, Botvinick EH. PMID: 12493955.
      View in: PubMed   Mentions:    Fields:    Translation:Humans