Midori Yenari, MD

Title(s)Professor, Neurology
SchoolSchool of Medicine
Address4150 Clement St
San Francisco CA 94121
Phone415-750-2011
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    Other Positions
    Title(s)UCSF Weill Institute for Neurosciences


    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Inflammatory mechanisms in cerebral ischemia
    NIH R01NS106441Mar 15, 2019 - Jan 31, 2024
    Role: Principal Investigator
    Calcium release-activated calcium (CRAC) channel inhibitors in experimental stroke
    NIH R03NS101246Sep 1, 2017 - Mar 31, 2020
    Role: Principal Investigator
    Heat shock proteins in brain ischemia and stroke
    NIH I01BX000589Jan 1, 2011 - Sep 30, 2019
    Role: Principal Investigator
    Inflammatory mechanisms in cerebral ischemia
    NIH R01NS040516Jun 1, 2010 - Oct 31, 2016
    Role: Principal Investigator
    MILD HYPOTHERMIA IN FOCAL CEREBRAL ISCHEMIA
    NIH K08NS001860Sep 30, 1995 - Jul 31, 2001
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Multimodal analysis of gene expression from postmortem brains and blood identifies synaptic vesicle trafficking genes to be associated with Parkinson's disease. Brief Bioinform. 2021 Jul 20; 22(4). Gao X, Huang Z, Feng C, Guan C, Li R, Xie H, Chen J, Li M, Que R, Deng B, Cao P, Li M, Lu J, Huang Y, Li M, Yang W, Yang X, Wen C, Liang X, Yang Q, Chao YX, Chan LL, Yenari MA, Jin K, Chaudhuri KR, Zhang J, Tan EK, Wang Q. PMID: 33079984.
      View in: PubMed   Mentions: 2     Fields:    
    2. Fibrinogen is an Independent Risk Factor for White Matter Hyperintensities in CADASIL but not in Sporadic Cerebral Small Vessel Disease Patients. Aging Dis. 2021 Jun; 12(3):801-811. Guo X, Deng B, Zhong L, Xie F, Qiu Q, Wei X, Wang W, Xu J, Liu G, Hon WPT, Yenari MA, Zhu S, Wang Q. PMID: 34094643.
      View in: PubMed   Mentions:
    3. Clinical perspectives on ischemic stroke. Exp Neurol. 2021 Apr; 338:113599. Mizuma A, Yenari MA. PMID: 33440204.
      View in: PubMed   Mentions: 1     Fields:    
    4. Cystatin C is a potential predictor of unfavorable outcomes for cerebral ischemia with intravenous tissue plasminogen activator treatment: A multicenter prospective nested case-control study. Eur J Neurol. 2021 Apr; 28(4):1265-1274. Chang Z, Zou H, Xie Z, Deng B, Que R, Huang Z, Weng G, Wu Z, Pan Y, Wang Y, Li M, Xie H, Zhu S, Xiong L, Ct Mok V, Jin K, Yenari MA, Wei X, Wang Q. PMID: 33277774.
      View in: PubMed   Mentions: 3     Fields:    
    5. Microglia, the brain's double agent. J Cereb Blood Flow Metab. 2020 12; 40(1_suppl):S3-S5. Yenari MA. PMID: 33208002.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    6. Heat Shock Protein 70 (HSP70) Induction: Chaperonotherapy for Neuroprotection after Brain Injury. Cells. 2020 09 02; 9(9). Kim JY, Barua S, Huang MY, Park J, Yenari MA, Lee JE. PMID: 32887360.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    7. Vascular, inflammatory and metabolic risk factors in relation to dementia in Parkinson's disease patients with type 2 diabetes mellitus. Aging (Albany NY). 2020 08 15; 12(15):15682-15704. Wang T, Yuan F, Chen Z, Zhu S, Chang Z, Yang W, Deng B, Que R, Cao P, Chao Y, Chan L, Pan Y, Wang Y, Xu L, Lyu Q, Chan P, Yenari MA, Tan EK, Wang Q. PMID: 32805719.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    8. Cofilin-actin rod formation in experimental stroke is attenuated by therapeutic hypothermia and overexpression of the inducible 70 kD inducible heat shock protein (Hsp70). Brain Circ. 2019 Oct-Dec; 5(4):225-233. Kurisu K, You J, Zheng Z, Won SJ, Swanson RA, Yenari MA. PMID: 31950099.
      View in: PubMed   Mentions:
    9. Heat shock protein signaling in brain ischemia and injury. Neurosci Lett. 2020 01 10; 715:134642. Kim JY, Kim JW, Yenari MA. PMID: 31759081.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    10. Models of poststroke depression and assessments of core depressive symptoms in rodents: How to choose? Exp Neurol. 2019 12; 322:113060. Tao X, Yang W, Zhu S, Que R, Liu C, Fan T, Wang J, Mo D, Zhang Z, Tan J, Jin K, Yenari MA, Song T, Wang Q. PMID: 31505162.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    11. Plasma Lipoprotein-associated Phospholipase A2 and Superoxide Dismutase are Independent Predicators of Cognitive Impairment in Cerebral Small Vessel Disease Patients: Diagnosis and Assessment. Aging Dis. 2019 Aug; 10(4):834-846. Zhu S, Wei X, Yang X, Huang Z, Chang Z, Xie F, Yang Q, Ding C, Xiang W, Yang H, Xia Y, Feng ZP, Sun HS, Yenari MA, Shi L, Mok VC, Wang Q. PMID: 31440388.
      View in: PubMed   Mentions:
    12. The role of NOX inhibitors in neurodegenerative diseases. IBRO Rep. 2019 Dec; 7:59-69. Barua S, Kim JY, Yenari MA, Lee JE. PMID: 31463415.
      View in: PubMed   Mentions:
    13. Therapeutic Hypothermia and Neuroprotection in Acute Neurological Disease. Curr Med Chem. 2019; 26(29):5430-5455. Kurisu K, Kim JY, You J, Yenari MA. PMID: 31057103.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    14. Triggering receptor expressed on myeloid cells-2 expression in the brain is required for maximal phagocytic activity and improved neurological outcomes following experimental stroke. J Cereb Blood Flow Metab. 2019 10; 39(10):1906-1918. Kurisu K, Zheng Z, Kim JY, Shi J, Kanoke A, Liu J, Hsieh CL, Yenari MA. PMID: 30523715.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    15. Microglial Calcium Release-Activated Calcium Channel Inhibition Improves Outcome from Experimental Traumatic Brain Injury and Microglia-Induced Neuronal Death. J Neurotrauma. 2019 04 01; 36(7):996-1007. Mizuma A, Kim JY, Kacimi R, Stauderman K, Dunn M, Hebbar S, Yenari MA. PMID: 30351197.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    16. Targeting Reperfusion Injury in the Age of Mechanical Thrombectomy. Stroke. 2018 07; 49(7):1796-1802. Mizuma A, You JS, Yenari MA. PMID: 29760275.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    17. Advances in Stroke 2017. Stroke. 2018 05; 49(5):e174-e199. Bernhardt J, Zorowitz RD, Becker KJ, Keller E, Saposnik G, Strbian D, Dichgans M, Woo D, Reeves M, Thrift A, Kidwell CS, Olivot JM, Goyal M, Pierot L, Bennett DA, Howard G, Ford GA, Goldstein LB, Planas AM, Yenari MA, Greenberg SM, Pantoni L, Amin-Hanjani S, Tymianski M. PMID: 29669874.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    18. The 70-kDa heat shock protein (Hsp70) as a therapeutic target for stroke. Expert Opin Ther Targets. 2018 03; 22(3):191-199. Kim JY, Han Y, Lee JE, Yenari MA. PMID: 29421932.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    19. Reconsidering Neuroprotection in the Reperfusion Era. Stroke. 2017 12; 48(12):3413-3419. Savitz SI, Baron JC, Yenari MA, Sanossian N, Fisher M. PMID: 29146878.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimals
    20. Anti-Inflammatory Targets for the Treatment of Reperfusion Injury in Stroke. Front Neurol. 2017; 8:467. Mizuma A, Yenari MA. PMID: 28936196.
      View in: PubMed   Mentions:
    21. NOX Inhibitors - A Promising Avenue for Ischemic Stroke. Exp Neurobiol. 2017 Aug; 26(4):195-205. Kim JY, Park J, Lee JE, Yenari MA. PMID: 28912642.
      View in: PubMed   Mentions:
    22. Therapeutic hypothermia for ischemic stroke; pathophysiology and future promise. Neuropharmacology. 2018 05 15; 134(Pt B):302-309. Kurisu K, Yenari MA. PMID: 28830757.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimals
    23. Hypothermia Identifies Dynamin as a Potential Therapeutic Target in Experimental Stroke. Ther Hypothermia Temp Manag. 2017 Sep; 7(3):171-177. Kim JY, Kim N, Lee JE, Yenari MA. PMID: 28665255.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    24. Activated complement protein C5a does not affect brain-derived endothelial cell viability and zonula occludens-1 levels following oxygen-glucose deprivation. Brain Circ. 2017 Jan-Mar; 3(1):14-20. Khoyetsyan A, Kacimi R, Tsakanova G, Boyajyan A, Arakelyan A, Yenari MA. PMID: 30276299.
      View in: PubMed   Mentions:
    25. 70-kDa Heat Shock Protein Downregulates Dynamin in Experimental Stroke: A New Therapeutic Target? Stroke. 2016 08; 47(8):2103-11. Kim JY, Kim N, Zheng Z, Lee JE, Yenari MA. PMID: 27387989.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    26. Postinjury Neuroplasticity in Central Neural Networks. Neural Plast. 2015; 2015:857085. Lee BH, Lim TH, Yoon YW, Yenari MA, Jeong Y. PMID: 26557389.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    27. Pharmacologic heat shock protein 70 induction confers cytoprotection against inflammation in gliovascular cells. Glia. 2015 Jul; 63(7):1200-12. Kacimi R, Yenari MA. PMID: 25802219.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    28. Triggering receptor expressed on myeloid cells 2 (TREM2) deficiency attenuates phagocytic activities of microglia and exacerbates ischemic damage in experimental stroke. J Neurosci. 2015 Feb 25; 35(8):3384-96. Kawabori M, Kacimi R, Kauppinen T, Calosing C, Kim JY, Hsieh CL, Nakamura MC, Yenari MA. PMID: 25716838.
      View in: PubMed   Mentions: 94     Fields:    Translation:AnimalsCells
    29. Inflammatory responses in brain ischemia. Curr Med Chem. 2015; 22(10):1258-77. Kawabori M, Yenari MA. PMID: 25666795.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansAnimalsCells
    30. Mechanisms and potential therapeutic applications of microglial activation after brain injury. CNS Neurosci Ther. 2015 Apr; 21(4):309-19. Kim JY, Kim N, Yenari MA. PMID: 25475659.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    31. Calcium-sensing receptor (CaSR) as a novel target for ischemic neuroprotection. Ann Clin Transl Neurol. 2014 Nov; 1(11):851-66. Kim JY, Ho H, Kim N, Liu J, Tu CL, Yenari MA, Chang W. PMID: 25540800.
      View in: PubMed   Mentions: 18     Fields:    
    32. The role of the microglia in acute CNS injury. Metab Brain Dis. 2015 Apr; 30(2):381-92. Kawabori M, Yenari MA. PMID: 24682762.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    33. Triggering Receptor Expressed on Myeloid Cells-2 Correlates to Hypothermic Neuroprotection in Ischemic Stroke. Ther Hypothermia Temp Manag. 2013 Dec 01; 3(4):189-198. Kawabori M, Hokari M, Zheng Z, Kim JY, Calosing C, Hsieh CL, Nakamura MC, Yenari MA. PMID: 24380032.
      View in: PubMed   Mentions: 15     Fields:    
    34. Microglial P2Y12 deficiency/inhibition protects against brain ischemia. PLoS One. 2013; 8(8):e70927. Webster CM, Hokari M, McManus A, Tang XN, Ma H, Kacimi R, Yenari MA. PMID: 23940669.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    35. Hypothermia and pharmacological regimens that prevent overexpression and overactivity of the extracellular calcium-sensing receptor protect neurons against traumatic brain injury. J Neurotrauma. 2013 Jul 01; 30(13):1170-6. Kim JY, Kim N, Yenari MA, Chang W. PMID: 23360235.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    36. The 70 kDa heat shock protein protects against experimental traumatic brain injury. Neurobiol Dis. 2013 Oct; 58:289-95. Kim JY, Kim N, Zheng Z, Lee JE, Yenari MA. PMID: 23816752.
      View in: PubMed   Mentions: 24     Fields:    Translation:Animals
    37. Mild hypothermia reduces tissue plasminogen activator-related hemorrhage and blood brain barrier disruption after experimental stroke. Ther Hypothermia Temp Manag. 2013 Jun; 3(2):74-83. Tang XN, Liu L, Koike MA, Yenari MA. PMID: 23781399.
      View in: PubMed   Mentions: 16     Fields:    
    38. Sphingolipids in cardiovascular and cerebrovascular systems: Pathological implications and potential therapeutic targets. World J Cardiol. 2013 Apr 26; 5(4):75-86. Kawabori M, Kacimi R, Karliner JS, Yenari MA. PMID: 23675553.
      View in: PubMed   Mentions:
    39. The immune modulating properties of the heat shock proteins after brain injury. Anat Cell Biol. 2013 Mar; 46(1):1-7. Kim JY, Yenari MA. PMID: 23560231.
      View in: PubMed   Mentions:
    40. Neuroprotection after cerebral ischemia. Ann N Y Acad Sci. 2013 Mar; 1278:25-32. Namura S, Ooboshi H, Liu J, Yenari MA. PMID: 23488559.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    41. The multifaceted effects of agmatine on functional recovery after spinal cord injury through Modulations of BMP-2/4/7 expressions in neurons and glial cells. PLoS One. 2013; 8(1):e53911. Park YM, Lee WT, Bokara KK, Seo SK, Park SH, Kim JH, Yenari MA, Park KA, Lee JE. PMID: 23349763.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    42. Temperature affects thrombolytic efficacy using rt-Pa and eptifibatide, an in vitro study: editorial commentary on Meunier et al., 2012. Ther Hypothermia Temp Manag. 2012 Dec; 2(4):166. Yenari MA. PMID: 23667779.
      View in: PubMed   Mentions: 1     Fields:    
    43. Bone marrow chimeras in the study of experimental stroke. Transl Stroke Res. 2012 Sep; 3(3):341-7. Tang XN, Zheng Z, Yenari MA. PMID: 24323809.
      View in: PubMed   Mentions: 7     Fields:    
    44. NADPH oxidase in stroke and cerebrovascular disease. Neurol Res. 2012 May; 34(4):338-45. Tang XN, Cairns B, Kim JY, Yenari MA. PMID: 22643077.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimals
    45. Neuroprotective mechanisms of hypothermia in brain ischaemia. Nat Rev Neurosci. 2012 Feb 22; 13(4):267-78. Yenari MA, Han HS. PMID: 22353781.
      View in: PubMed   Mentions: 167     Fields:    Translation:Humans
    46. NOX inhibitors as a therapeutic strategy for stroke and neurodegenerative disease. Curr Drug Targets. 2012 Feb; 13(2):199-206. Cairns B, Kim JY, Tang XN, Yenari MA. PMID: 22204319.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    47. Therapeutic hypothermia in stroke. Stroke Res Treat. 2011; 2011:157969. Yenari MA, Colbourne F, Hemmen TM, Han HS, Krieger D. PMID: 22315703.
      View in: PubMed   Mentions:
    48. Anti-inflammatory properties and pharmacological induction of Hsp70 after brain injury. Inflammopharmacology. 2012 Jun; 20(3):177-85. Kim N, Kim JY, Yenari MA. PMID: 22246599.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimals
    49. Hyperglycemia promotes tissue plasminogen activator-induced hemorrhage by Increasing superoxide production. Ann Neurol. 2011 Oct; 70(4):583-90. Won SJ, Tang XN, Suh SW, Yenari MA, Swanson RA. PMID: 22002675.
      View in: PubMed   Mentions: 58     Fields:    Translation:Animals
    50. Significance of marrow-derived nicotinamide adenine dinucleotide phosphate oxidase in experimental ischemic stroke. Ann Neurol. 2011 Oct; 70(4):606-15. Tang XN, Zheng Z, Giffard RG, Yenari MA. PMID: 22028221.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    51. Brain 11: what's new in stroke research? Expert Rev Neurother. 2011 Sep; 11(9):1235-7. Yenari MA, Lee JE. PMID: 21864067.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    52. Therapeutic hypothermia after cardiac arrest: experience at an academically affiliated community-based veterans affairs medical center. Stroke Res Treat. 2011; 2011:791639. Shah MP, Zimmerman L, Bullard J, Yenari MA. PMID: 21822471.
      View in: PubMed   Mentions:
    53. Simvastatin prevents dopaminergic neurodegeneration in experimental parkinsonian models: the association with anti-inflammatory responses. PLoS One. 2011; 6(6):e20945. Yan J, Xu Y, Zhu C, Zhang L, Wu A, Yang Y, Xiong Z, Deng C, Huang XF, Yenari MA, Yang YG, Ying W, Wang Q. PMID: 21731633.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    54. Mild Hypothermia Suppresses Calcium-Sensing Receptor (CaSR) Induction Following Forebrain Ischemia While Increasing GABA-B Receptor 1 (GABA-B-R1) Expression. Transl Stroke Res. 2011 Jun 01; 2(2):195-201. Kim JY, Kim N, Yenari MA, Chang W. PMID: 21731589.
      View in: PubMed   Mentions: 18     Fields:    
    55. Endotoxin-activated microglia injure brain derived endothelial cells via NF-?B, JAK-STAT and JNK stress kinase pathways. J Inflamm (Lond). 2011 Mar 07; 8:7. Kacimi R, Giffard RG, Yenari MA. PMID: 21385378.
      View in: PubMed   Mentions:
    56. Direct protection of cultured neurons from ischemia-like injury by minocycline. Anat Cell Biol. 2010 Dec; 43(4):325-31. Huang WC, Qiao Y, Xu L, Kacimi R, Sun X, Giffard RG, Yenari MA. PMID: 21267407.
      View in: PubMed   Mentions:
    57. Therapeutic hypothermia for brain ischemia: where have we come and where do we go? Stroke. 2010 Oct; 41(10 Suppl):S72-4. Yenari MA, Hemmen TM. PMID: 20876510.
      View in: PubMed   Mentions: 48     Fields:    Translation:Humans
    58. Microglial activation in stroke: therapeutic targets. Neurotherapeutics. 2010 Oct; 7(4):378-91. Yenari MA, Kauppinen TM, Swanson RA. PMID: 20880502.
      View in: PubMed   Mentions: 148     Fields:    Translation:HumansAnimalsCells
    59. Endogenous agmatine inhibits cerebral vascular matrix metalloproteinases expression by regulating activating transcription factor 3 and endothelial nitric oxide synthesis. Curr Neurovasc Res. 2010 Aug; 7(3):201-12. Jung HJ, Yang MZ, Kwon KH, Yenari MA, Choi YJ, Lee WT, Park KA, Lee JE. PMID: 20560878.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    60. Digitally quantifying cerebral hemorrhage using Photoshop and Image J. J Neurosci Methods. 2010 Jul 15; 190(2):240-3. Tang XN, Berman AE, Swanson RA, Yenari MA. PMID: 20452374.
      View in: PubMed   Mentions: 29     Fields:    Translation:Animals
    61. Statins: multiple neuroprotective mechanisms in neurodegenerative diseases. Exp Neurol. 2011 Jul; 230(1):27-34. Wang Q, Yan J, Chen X, Li J, Yang Y, Weng J, Deng C, Yenari MA. PMID: 20406638.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    62. Alterations in 5-HT2A receptor binding in various brain regions among 6-hydroxydopamine-induced Parkinsonian rats. Synapse. 2010 Mar; 64(3):224-30. Li Y, Huang XF, Deng C, Meyer B, Wu A, Yu Y, Ying W, Yang GY, Yenari MA, Wang Q. PMID: 19862688.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    63. Hypothermia as a cytoprotective strategy in ischemic tissue injury. Ageing Res Rev. 2010 Jan; 9(1):61-8. Tang XN, Yenari MA. PMID: 19833233.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    64. Does inflammation after stroke affect the developing brain differently than adult brain? Dev Neurosci. 2009; 31(5):378-93. Vexler ZS, Yenari MA. PMID: 19672067.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    65. Pyruvate protects against experimental stroke via an anti-inflammatory mechanism. Neurobiol Dis. 2009 Oct; 36(1):223-31. Wang Q, van Hoecke M, Tang XN, Lee H, Zheng Z, Swanson RA, Yenari MA. PMID: 19635562.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    66. Clinical application of therapeutic hypothermia in stroke. Neurol Res. 2009 May; 31(4):331-5. Liu L, Yenari MA. PMID: 19508813.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    67. A role for TREM2 ligands in the phagocytosis of apoptotic neuronal cells by microglia. J Neurochem. 2009 May; 109(4):1144-56. Hsieh CL, Koike M, Spusta SC, Niemi EC, Yenari M, Nakamura MC, Seaman WE. PMID: 19302484.
      View in: PubMed   Mentions: 165     Fields:    Translation:AnimalsCells
    68. Combination therapy with hypothermia for treatment of cerebral ischemia. J Neurotrauma. 2009 Mar; 26(3):325-31. Tang XN, Liu L, Yenari MA. PMID: 19216635.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    69. Glucose and NADPH oxidase drive neuronal superoxide formation in stroke. Ann Neurol. 2008 Dec; 64(6):654-63. Suh SW, Shin BS, Ma H, Van Hoecke M, Brennan AM, Yenari MA, Swanson RA. PMID: 19107988.
      View in: PubMed   Mentions: 114     Fields:    Translation:AnimalsCells
    70. Inflammation and NFkappaB activation is decreased by hypothermia following global cerebral ischemia. Neurobiol Dis. 2009 Feb; 33(2):301-12. Webster CM, Kelly S, Koike MA, Chock VY, Giffard RG, Yenari MA. PMID: 19063968.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    71. Metabolic downregulation: a key to successful neuroprotection? Stroke. 2008 Oct; 39(10):2910-7. Yenari M, Kitagawa K, Lyden P, Perez-Pinzon M. PMID: 18658035.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimalsCells
    72. epsilonPKC confers acute tolerance to cerebral ischemic reperfusion injury. Neurosci Lett. 2008 Aug 15; 441(1):120-4. Bright R, Sun GH, Yenari MA, Steinberg GK, Mochly-Rosen D. PMID: 18586397.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    73. FasL shedding is reduced by hypothermia in experimental stroke. J Neurochem. 2008 Jul; 106(2):541-50. Liu L, Kim JY, Koike MA, Yoon YJ, Tang XN, Ma H, Lee H, Steinberg GK, Lee JE, Yenari MA. PMID: 18410517.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    74. Monitoring the protective effects of minocycline treatment with radiolabeled annexin V in an experimental model of focal cerebral ischemia. J Nucl Med. 2007 Nov; 48(11):1822-8. Tang XN, Wang Q, Koike MA, Cheng D, Goris ML, Blankenberg FG, Yenari MA. PMID: 17942809.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    75. Conditions of protection by hypothermia and effects on apoptotic pathways in a rat model of permanent middle cerebral artery occlusion. J Neurosurg. 2007 Sep; 107(3):636-41. Zhao H, Wang JQ, Shimohata T, Sun G, Yenari MA, Sapolsky RM, Steinberg GK. PMID: 17886565.
      View in: PubMed   Mentions: 24     Fields:    Translation:Animals
    76. Anti-inflammatory effects of the 70 kDa heat shock protein in experimental stroke. J Cereb Blood Flow Metab. 2008 Jan; 28(1):53-63. Zheng Z, Kim JY, Ma H, Lee JE, Yenari MA. PMID: 17473852.
      View in: PubMed   Mentions: 97     Fields:    Translation:AnimalsCells
    77. Subclinical embolization after carotid artery stenting: new lesions on diffusion-weighted magnetic resonance imaging occur postprocedure. J Vasc Surg. 2007 May; 45(5):867-72; discussion 872-4. Rapp JH, Wakil L, Sawhney R, Pan XM, Yenari MA, Glastonbury C, Coogan S, Wintermark M. PMID: 17376643.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    78. Therapeutic hypothermia: neuroprotective mechanisms. Front Biosci. 2007 Jan 01; 12:816-25. Liu L, Yenari MA. PMID: 17127332.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansCells
    79. The inflammatory response in stroke. J Neuroimmunol. 2007 Mar; 184(1-2):53-68. Wang Q, Tang XN, Yenari MA. PMID: 17188755.
      View in: PubMed   Mentions: 432     Fields:    Translation:HumansAnimals
    80. INTRODUCTION: Immune mechanisms of neurodegeneration. Clin Neurosci Res. 2006 Dec; 6(5):225. Yenari MA, Swanson RA. PMID: 17464366.
      View in: PubMed   Mentions:
    81. Inflammation in adult and neonatal stroke. Clin Neurosci Res. 2006 Dec 01; 6(5):293-313. Vexler ZS, Tang XN, Yenari MA. PMID: 20300490.
      View in: PubMed   Mentions:
    82. Effects of high dose of simvastatin on levels of dopamine and its reuptake in prefrontal cortex and striatum among SD rats. Neurosci Lett. 2006 Nov 20; 408(3):189-93. Wang Q, Tang XN, Wang L, Yenari MA, Ying W, Goh BC, Lee HS, Wilder-Smith EP, Wong PT. PMID: 16996211.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    83. Influence of hypothermia on post-ischemic inflammation: role of nuclear factor kappa B (NFkappaB). Neurochem Int. 2006 Jul; 49(2):164-9. Yenari MA, Han HS. PMID: 16750872.
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    84. Microglia potentiate damage to blood-brain barrier constituents: improvement by minocycline in vivo and in vitro. Stroke. 2006 Apr; 37(4):1087-93. Yenari MA, Xu L, Tang XN, Qiao Y, Giffard RG. PMID: 16497985.
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    85. 99mTc-HYNIC-annexin V SPECT imaging of acute stroke and its response to neuroprotective therapy with anti-Fas ligand antibody. Eur J Nucl Med Mol Imaging. 2006 May; 33(5):566-74. Blankenberg FG, Kalinyak J, Liu L, Koike M, Cheng D, Goris ML, Green A, Vanderheyden JL, Tong DC, Yenari MA. PMID: 16477433.
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    86. Therapeutic hypothermia for acute stroke. Int J Stroke. 2006 Feb; 1(1):9-19. Lyden PD, Krieger D, Yenari M, Dietrich WD. PMID: 18706063.
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    87. The application of HSP70 as a target for gene therapy. Front Biosci. 2006 Jan 01; 11:699-707. Zheng Z, Yenari MA. PMID: 16146762.
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    88. Biphasic cytochrome c release after transient global ischemia and its inhibition by hypothermia. J Cereb Blood Flow Metab. 2005 Sep; 25(9):1119-29. Zhao H, Yenari MA, Cheng D, Sapolsky RM, Steinberg GK. PMID: 15789032.
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    89. Reduction in levels of matrix metalloproteinases and increased expression of tissue inhibitor of metalloproteinase-2 in response to mild hypothermia therapy in experimental stroke. J Neurosurg. 2005 Aug; 103(2):289-97. Lee JE, Yoon YJ, Moseley ME, Yenari MA. PMID: 16175859.
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    90. Antiapoptotic and anti-inflammatory mechanisms of heat-shock protein protection. Ann N Y Acad Sci. 2005 Aug; 1053:74-83. Yenari MA, Liu J, Zheng Z, Vexler ZS, Lee JE, Giffard RG. PMID: 16179510.
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    91. Mild hypothermia decreases GSK3beta expression following global cerebral ischemia. Neurocrit Care. 2005; 2(2):212-7. Kelly S, Cheng D, Steinberg GK, Yenari MA. PMID: 16159068.
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    92. Gene therapy in neurological disease. Methods Mol Med. 2005; 104:75-88. Yenari MA, Sapolsky RM. PMID: 15454665.
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    93. Post-ischemic inflammation: molecular mechanisms and therapeutic implications. Neurol Res. 2004 Dec; 26(8):884-92. Zheng Z, Yenari MA. PMID: 15727272.
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    94. Protein kinase C delta mediates cerebral reperfusion injury in vivo. J Neurosci. 2004 Aug 04; 24(31):6880-8. Bright R, Raval AP, Dembner JM, Pérez-Pinzón MA, Steinberg GK, Yenari MA, Mochly-Rosen D. PMID: 15295022.
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    95. Chaperones, protein aggregation, and brain protection from hypoxic/ischemic injury. J Exp Biol. 2004 Aug; 207(Pt 18):3213-20. Giffard RG, Xu L, Zhao H, Carrico W, Ouyang Y, Qiao Y, Sapolsky R, Steinberg G, Hu B, Yenari MA. PMID: 15299042.
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    96. Glycogen synthase kinase 3beta inhibitor Chir025 reduces neuronal death resulting from oxygen-glucose deprivation, glutamate excitotoxicity, and cerebral ischemia. Exp Neurol. 2004 Aug; 188(2):378-86. Kelly S, Zhao H, Hua Sun G, Cheng D, Qiao Y, Luo J, Martin K, Steinberg GK, Harrison SD, Yenari MA. PMID: 15246837.
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    97. Bcl-2 transfection via herpes simplex virus blocks apoptosis-inducing factor translocation after focal ischemia in the rat. J Cereb Blood Flow Metab. 2004 Jun; 24(6):681-92. Zhao H, Yenari MA, Cheng D, Barreto-Chang OL, Sapolsky RM, Steinberg GK. PMID: 15181376.
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    98. Therapeutic hypothermia for acute ischemic stroke: what do laboratory studies teach us? Stroke. 2004 Jun; 35(6):1482-9. Krieger DW, Yenari MA. PMID: 15073396.
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    99. The 70 kDa heat shock protein suppresses matrix metalloproteinases in astrocytes. Neuroreport. 2004 Mar 01; 15(3):499-502. Lee JE, Kim YJ, Kim JY, Lee WT, Yenari MA, Giffard RG. PMID: 15094511.
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    100. Catalase over-expression protects striatal neurons from transient focal cerebral ischemia. Neuroreport. 2004 Mar 01; 15(3):413-6. Gu W, Zhao H, Yenari MA, Sapolsky RM, Steinberg GK. PMID: 15094494.
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    101. Detection of focal hypoxic-ischemic injury and neuronal stress in a rodent model of unilateral MCA occlusion/reperfusion using radiolabeled annexin V. Eur J Nucl Med Mol Imaging. 2004 May; 31(5):733-9. Mari C, Karabiyikoglu M, Goris ML, Tait JF, Yenari MA, Blankenberg FG. PMID: 14985868.
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    102. Mild postischemic hypothermia prolongs the time window for gene therapy by inhibiting cytochrome C release. Stroke. 2004 Feb; 35(2):572-7. Zhao H, Yenari MA, Sapolsky RM, Steinberg GK. PMID: 14726551.
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    103. Pathophysiology of acute ischemic stroke. Cleve Clin J Med. 2004 Jan; 71 Suppl 1:S25-7. Yenari MA. PMID: 14964478.
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    104. Many mechanisms for hsp70 protection from cerebral ischemia. J Neurosurg Anesthesiol. 2004 Jan; 16(1):53-61. Giffard RG, Yenari MA. PMID: 14676570.
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    105. Cellular and molecular events underlying ischemia-induced neuronal apoptosis. Drug News Perspect. 2003 Oct; 16(8):497-503. Zheng Z, Zhao H, Steinberg GK, Yenari MA. PMID: 14668947.
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    106. Mild hypothermia inhibits inflammation after experimental stroke and brain inflammation. Stroke. 2003 Oct; 34(10):2495-501. Deng H, Han HS, Cheng D, Sun GH, Yenari MA. PMID: 12970518.
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    107. Attenuation of nitric oxide synthase isoform expression by mild hypothermia after focal cerebral ischemia: variations depending on timing of cooling. J Neurosurg. 2003 Jun; 98(6):1271-6. Karabiyikoglu M, Han HS, Yenari MA, Steinberg GK. PMID: 12816275.
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    108. Mild hypothermia inhibits nuclear factor-kappaB translocation in experimental stroke. J Cereb Blood Flow Metab. 2003 May; 23(5):589-98. Han HS, Karabiyikoglu M, Kelly S, Sobel RA, Yenari MA. PMID: 12771574.
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    109. Gene therapy and hypothermia for stroke treatment. Ann N Y Acad Sci. 2003 May; 993:54-68; discussion 79-81. Yenari MA, Zhao H, Giffard RG, Sobel RA, Sapolsky RM, Steinberg GK. PMID: 12853295.
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    110. Bcl-2 overexpression protects against neuron loss within the ischemic margin following experimental stroke and inhibits cytochrome c translocation and caspase-3 activity. J Neurochem. 2003 May; 85(4):1026-36. Zhao H, Yenari MA, Cheng D, Sapolsky RM, Steinberg GK. PMID: 12716434.
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    111. Prospects for the treatment of stroke using gene therapy. Expert Rev Neurother. 2003 May; 3(3):357-72. Zhao H, Yenari MA, Sapolsky RM, Steinberg GK. PMID: 19810903.
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    112. Cellular targets of brain inflammation in stroke. Curr Opin Investig Drugs. 2003 May; 4(5):522-9. Han HS, Yenari MA. PMID: 12833644.
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    113. Effects of mild hypothermia on superoxide anion production, superoxide dismutase expression, and activity following transient focal cerebral ischemia. Neurobiol Dis. 2002 Oct; 11(1):28-42. Maier CM, Sun GH, Cheng D, Yenari MA, Chan PH, Steinberg GK. PMID: 12460544.
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    114. Gene transfer of HSP72 protects cornu ammonis 1 region of the hippocampus neurons from global ischemia: influence of Bcl-2. Ann Neurol. 2002 Aug; 52(2):160-7. Kelly S, Zhang ZJ, Zhao H, Xu L, Giffard RG, Sapolsky RM, Yenari MA, Steinberg GK. PMID: 12210785.
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    115. Use of diffusion weighted MRI to predict the occurrence and severity of hemorrhagic transformation in a rabbit model of embolic stroke. Brain Res. 2002 Jul 19; 944(1-2):32-9. Adami A, Thijs V, Tong DC, Beaulieu C, Moseley ME, Yenari MA. PMID: 12106663.
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    116. Influence of mild hypothermia on inducible nitric oxide synthase expression and reactive nitrogen production in experimental stroke and inflammation. J Neurosci. 2002 May 15; 22(10):3921-8. Han HS, Qiao Y, Karabiyikoglu M, Giffard RG, Yenari MA. PMID: 12019311.
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    117. Neuroprotection: heat shock proteins. Curr Med Res Opin. 2002; 18 Suppl 2:s55-60. Kelly S, Yenari MA. PMID: 12365831.
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    118. Mild hypothermia reduces apoptosis of mouse neurons in vitro early in the cascade. J Cereb Blood Flow Metab. 2002 Jan; 22(1):21-8. Xu L, Yenari MA, Steinberg GK, Giffard RG. PMID: 11807390.
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    119. Mild hypothermia attenuates cytochrome c release but does not alter Bcl-2 expression or caspase activation after experimental stroke. J Cereb Blood Flow Metab. 2002 Jan; 22(1):29-38. Yenari MA, Iwayama S, Cheng D, Sun GH, Fujimura M, Morita-Fujimura Y, Chan PH, Steinberg GK. PMID: 11807391.
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    120. Heat shock proteins and neuroprotection. Adv Exp Med Biol. 2002; 513:281-99. Yenari MA. PMID: 12575825.
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