Sabra Inslicht, PhD
Title(s) | UCSF Weill Institute for Neurosciences |
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Biography University of California, San Francisco, San Francisco, CA | Postdoctoral Studies | 2008 | Graduate Division | Rutgers University, New Brunswick, NJ | BA | 1994 | Psychology | University of Haifa, Haifa, Israel | | 1993 | Psychology Honors Program | University of Pittsburgh, Pittsburgh, PA | MS | 1998 | Clinical and Health Psychology | University of Pittsburgh, Pittsburgh, PA | Ph.D. | 1998 | Clinical and Health Psychology | VA Palo Alto Healthcare System, Palo Alto, CA | Internship | 2002 | Clinical Psychology | Stanford University Medical Center, Stanford, CA | Postdoctoral Studies | 2003 | Child and Adolescent Clinical Psychology |
Overview My research goals include: 1) identifying psychobiological causes and consequences of traumatic stress symptoms; 2) utilizing fear conditioning and extinction models to better understand PTSD; 3) characterizing sex differences in the biology of PTSD; 4) improving measurement techniques in the laboratory and the field such as with mobile health devices; and 5) conducting research that will inform novel interventions for ameliorating prolonged PTSD responses.
Research ORNG Applications Bibliographic
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Richards A, Kanady JC, Huie JR, Straus LD, Inslicht SS, Levihn-Coon A, Metzler TJ, Neylan TC. Work by day and sleep by night, do not sleep too little or too much: Effects of sleep duration, time of day and circadian synchrony on flanker-task performance in internet brain-game users from teens to advanced age. J Sleep Res. 2019 Oct 20; e12919. PMID: 31631467.
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Cowden Hindash AH, Lujan C, Howard M, O'Donovan A, Richards A, Neylan TC, Inslicht SS. Gender Differences in Threat Biases: Trauma Type Matters in Posttraumatic Stress Disorder. J Trauma Stress. 2019 Oct 07. PMID: 31590206.
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Jovanovic T, Duncan EJ, Kaye J, Garza K, Norrholm SD, Inslicht SS, Neylan TC, Mathew SJ, Iosifescu D, Rothbaum BO, Mayberg HS, Dunlop BW. Psychophysiological treatment outcomes: Corticotropin-releasing factor type 1 receptor antagonist increases inhibition of fear-potentiated startle in PTSD patients. Psychophysiology. 2019 Feb 26; e13356. PMID: 30807663.
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Young DA, Neylan TC, Chao LL, O'Donovan A, Metzler TJ, Inslicht SS. Child abuse interacts with hippocampal and corpus callosum volume on psychophysiological response to startling auditory stimuli in a sample of veterans. J Psychiatr Res. 2019 Apr; 111:16-23. PMID: 30660809.
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Küffer A, Straus LD, Prather AA, Inslicht SS, Richards A, Shigenaga JK, Madden E, Metzler TJ, Neylan TC, O'Donovan A. Altered overnight levels of pro-inflammatory cytokines in men and women with posttraumatic stress disorder. Psychoneuroendocrinology. 2019 Apr; 102:114-120. PMID: 30544002.
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Gibson CJ, Li Y, Inslicht SS, Seal KH, Byers AL. Gender Differences in Cardiovascular Risk Related to Diabetes and Posttraumatic Stress Disorder. Am J Geriatr Psychiatry. 2018 12; 26(12):1268-1272. PMID: 30314941.
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Young DA, Chao L, Neylan TC, O'Donovan A, Metzler TJ, Inslicht SS. Association among anterior cingulate cortex volume, psychophysiological response, and PTSD diagnosis in a Veteran sample. Neurobiol Learn Mem. 2018 11; 155:189-196. PMID: 30086395.
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Niles AN, Luxenberg A, Neylan TC, Inslicht SS, Richards A, Metzler TJ, Hlavin J, Deng J, O'Donovan A. Effects of Threat Context, Trauma History, and Posttraumatic Stress Disorder Status on Physiological Startle Reactivity in Gulf War Veterans. J Trauma Stress. 2018 08; 31(4):579-590. PMID: 30058728.
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Inslicht SS, Neylan TC. Patterns of Zolpidem Use in Male and Female Veterans Following Revised FDA Dosing Guidelines. J Clin Sleep Med. 2018 07 15; 14(7):1093-1094. PMID: 29991413.
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Young DA, Neylan TC, O'Donovan A, Metzler T, Richards A, Ross JA, Inslicht SS. The interaction of BDNF Val66Met, PTSD, and child abuse on psychophysiological reactivity and HPA axis function in a sample of Gulf War Veterans. J Affect Disord. 2018 08 01; 235:52-60. PMID: 29649711.
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Young DA, Inslicht SS, Metzler TJ, Neylan TC, Ross JA. The effects of early trauma and the FKBP5 gene on PTSD and the HPA axis in a clinical sample of Gulf War veterans. Psychiatry Res. 2018 12; 270:961-966. PMID: 29576410.
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McCaslin SE, Herbst ED, Armitage NH, Allen I, Neylan T, Becket-Davenport C, Choucroun G, Best S, Inslicht SS. Deployment Anxiety Reduction Training: A Pilot Study of Acceptability and Feasibility in Current or Recent Active Duty Service Members. Mil Med. 2018 03 01; 183(suppl_1):371-378. PMID: 29635621.
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Gibson CJ, Richards A, Villanueva C, Barrientos M, Neylan TC, Inslicht SS. Subjective Sleep Related to Post Traumatic Stress Disorder Symptoms among Trauma-Exposed Men and Women. Behav Sleep Med. 2019 Jul-Aug; 17(4):492-501. PMID: 29172723.
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Inslicht SS, Rao MN, Richards A, O'Donovan A, Gibson CJ, Baum T, Metzler TJ, Neylan TC. Sleep and hypothalamic pituitary adrenal axis responses to metyrapone in posttraumatic stress disorder. Psychoneuroendocrinology. 2018 02; 88:136-143. PMID: 29268182.
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Strigo IA, Spadoni AD, Inslicht SS, Simmons AN. Repeated Exposure to Experimental Pain Differentiates Combat Traumatic Brain Injury with and without Post-Traumatic Stress Disorder. J Neurotrauma. 2018 01 15; 35(2):297-307. PMID: 28931334.
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Alexandra Kredlow M, Pineles SL, Inslicht SS, Marin MF, Milad MR, Otto MW, Orr SP. Assessment of skin conductance in African American and Non-African American participants in studies of conditioned fear. Psychophysiology. 2017 Nov; 54(11):1741-1754. PMID: 28675471.
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Richards A, Inslicht SS, Metzler TJ, Mohlenhoff BS, Rao MN, O'Donovan A, Neylan TC. Sleep and Cognitive Performance From Teens To Old Age: More Is Not Better. Sleep. 2017 Jan 01; 40(1). PMID: 28364476.
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Talbot LS, Rao MN, Cohen BE, Richards A, Inslicht SS, O'Donovan A, Maguen S, Metzler TJ, Neylan TC. Metabolic risk factors and posttraumatic stress disorder: the role of sleep in young, healthy adults. Psychosom Med. 2015 May; 77(4):383-91. PMID: 25886830.
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Rao MN, Chau A, Madden E, Inslicht S, Talbot L, Richards A, O'Donovan A, Ruoff L, Grunfeld C, Neylan TC. Hyperinsulinemic response to oral glucose challenge in individuals with posttraumatic stress disorder. Psychoneuroendocrinology. 2014 Nov; 49:171-81. PMID: 25108160.
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Meffert SM, Henn-Haase C, Metzler TJ, Qian M, Best S, Hirschfeld A, McCaslin S, Inslicht S, Neylan TC, Marmar CR. Prospective study of police officer spouse/partners: a new pathway to secondary trauma and relationship violence? PLoS One. 2014; 9(7):e100663. PMID: 24987848.
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Inslicht SS, Richards A, Madden E, Rao MN, O'Donovan A, Talbot LS, Rucker E, Metzler TJ, Hauger RL, Neylan TC. Sex differences in neurosteroid and hormonal responses to metyrapone in posttraumatic stress disorder. Psychopharmacology (Berl). 2014 Sep; 231(17):3581-95. PMID: 24952092.
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Galatzer-Levy IR, Steenkamp MM, Brown AD, Qian M, Inslicht S, Henn-Haase C, Otte C, Yehuda R, Neylan TC, Marmar CR. Cortisol response to an experimental stress paradigm prospectively predicts long-term distress and resilience trajectories in response to active police service. J Psychiatr Res. 2014 Sep; 56:36-42. PMID: 24952936.
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Richards A, Metzler TJ, Ruoff LM, Inslicht SS, Rao M, Talbot LS, Neylan TC. Sex differences in objective measures of sleep in post-traumatic stress disorder and healthy control subjects. J Sleep Res. 2013 Dec; 22(6):679-87. PMID: 23763708.
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Inslicht SS, Metzler TJ, Garcia NM, Pineles SL, Milad MR, Orr SP, Marmar CR, Neylan TC. Sex differences in fear conditioning in posttraumatic stress disorder. J Psychiatr Res. 2013 Jan; 47(1):64-71. PMID: 23107307.
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Inslicht SS, Otte C, McCaslin SE, Apfel BA, Henn-Haase C, Metzler T, Yehuda R, Neylan TC, Marmar CR. Cortisol awakening response prospectively predicts peritraumatic and acute stress reactions in police officers. Biol Psychiatry. 2011 Dec 01; 70(11):1055-62. PMID: 21906725.
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Apfel BA, Otte C, Inslicht SS, McCaslin SE, Henn-Haase C, Metzler TJ, Makotkine I, Yehuda R, Neylan TC, Marmar CR. Pretraumatic prolonged elevation of salivary MHPG predicts peritraumatic distress and symptoms of post-traumatic stress disorder. J Psychiatr Res. 2011 Jun; 45(6):735-41. PMID: 21196013.
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Yuan C, Wang Z, Inslicht SS, McCaslin SE, Metzler TJ, Henn-Haase C, Apfel BA, Tong H, Neylan TC, Fang Y, Marmar CR. Protective factors for posttraumatic stress disorder symptoms in a prospective study of police officers. Psychiatry Res. 2011 Jun 30; 188(1):45-50. PMID: 21095622.
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Herbst E, Metzler TJ, Lenoci M, McCaslin SE, Inslicht S, Marmar CR, Neylan TC. Adaptation effects to sleep studies in participants with and without chronic posttraumatic stress disorder. Psychophysiology. 2010 Nov; 47(6):1127-33. PMID: 20456661.
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Wang Z, Inslicht SS, Metzler TJ, Henn-Haase C, McCaslin SE, Tong H, Neylan TC, Marmar CR. A prospective study of predictors of depression symptoms in police. Psychiatry Res. 2010 Feb 28; 175(3):211-6. PMID: 20044144.
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Maguen S, Metzler TJ, McCaslin SE, Inslicht SS, Henn-Haase C, Neylan TC, Marmar CR. Routine work environment stress and PTSD symptoms in police officers. J Nerv Ment Dis. 2009 Oct; 197(10):754-60. PMID: 19829204.
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Inslicht SS, McCaslin SE, Metzler TJ, Henn-Haase C, Hart SL, Maguen S, Neylan TC, Marmar CR. Family psychiatric history, peritraumatic reactivity, and posttraumatic stress symptoms: a prospective study of police. J Psychiatr Res. 2010 Jan; 44(1):22-31. PMID: 19683259.
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Wang Z, Xiao Z, Inslicht SS, Tong H, Jiang W, Wang X, Metzler T, Marmar CR, Jiang S. Low expression of catecholamine-O-methyl-transferase gene in obsessive-compulsive disorder. J Anxiety Disord. 2009 Jun; 23(5):660-4. PMID: 19269131.
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McCaslin SE, Inslicht SS, Metzler TJ, Henn-Haase C, Maguen S, Neylan TC, Choucroun G, Marmar CR. Trait dissociation predicts posttraumatic stress disorder symptoms in a prospective study of urban police officers. J Nerv Ment Dis. 2008 Dec; 196(12):912-8. PMID: 19077859.
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Meffert SM, Metzler TJ, Henn-Haase C, McCaslin S, Inslicht S, Chemtob C, Neylan T, Marmar CR. A prospective study of trait anger and PTSD symptoms in police. J Trauma Stress. 2008 Aug; 21(4):410-6. PMID: 18720397.
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McCaslin SE, Inslicht SS, Neylan TC, Metzler TJ, Otte C, Lenoci M, Henn-Haase C, Best S, Yehuda R, Marmar CR. Association between alexithymia and neuroendocrine response to psychological stress in police academy recruits. Ann N Y Acad Sci. 2006 Jul; 1071:425-7. PMID: 16891590.
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Inslicht SS, Marmar CR, Neylan TC, Metzler TJ, Hart SL, Otte C, McCaslin SE, Larkin GL, Hyman KB, Baum A. Increased cortisol in women with intimate partner violence-related posttraumatic stress disorder. Ann N Y Acad Sci. 2006 Jul; 1071:428-9. PMID: 16891591.
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Inslicht SS, Marmar CR, Neylan TC, Metzler TJ, Hart SL, Otte C, McCaslin SE, Larkin GL, Hyman KB, Baum A. Increased cortisol in women with intimate partner violence-related posttraumatic stress disorder. Psychoneuroendocrinology. 2006 Aug; 31(7):825-38. PMID: 16716530.
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Hamann HA, Somers TJ, Smith AW, Inslicht SS, Baum A. Posttraumatic stress associated with cancer history and BRCA1/2 genetic testing. Psychosom Med. 2005 Sep-Oct; 67(5):766-72. PMID: 16204436.
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Dougall AL, Herberman HB, Delahanty DL, Inslicht SS, Baum A. Similarity of prior trauma exposure as a determinant of chronic stress responding to an airline disaster. J Consult Clin Psychol. 2000 Apr; 68(2):290-5. PMID: 10780129.
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