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Karen Seal, MD

Title(s)Professor, Medicine
SchoolSchool of Medicine
Address4150 Clement St.
San Francisco CA 94121
Phone415-221-4810 ext. 4852
ORCID ORCID Icon0000-0002-6676-9117 Additional info
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    Collapse Biography 
    Collapse Education and Training
    Brown University, Providence, RIBS05/1985Neuroscience
    Stanford University School of Medicine, Stanford, CAMD05/1994Medicine
    University of California, San FranciscoResidency Internal Medicine
    University of California, Berkeley, Berkeley, CAMPH05/1998Epidemiology
    University of California, San Francisco, Center for AIDS Prevention Studies, San FranciscoPost-Doctoral Fellowship05/2003
    Collapse Awards and Honors
    Brown University1981  - 1985Sigma Xi
    Stanford University School of Medicine1991Peninsula Community Scholar's Award for Community Service
    UCSF2010UCSF Excellence in Teaching Award in Medical Education
    VA2016Federal Employee of the Year for Research

    Collapse Overview 
    Collapse Overview
    Dr. Karen Seal is a Professor of Medicine and Psychiatry in Residence at the University of California, San Francisco (UCSF). Based at the San Francisco VA Health Care System (SFVAHCS), she serves as Chief of the Integrative Health Service. In this capacity and as a general internist and integrative medicine physician, she oversees several interdisciplinary clinics including a post-9/11 Integrated Care Clinic for Iraq and Afghanistan veterans, the Integrated Pain Team Clinic, and the Integrative Health and Wellness Clinic which serve high-risk, high-needs veterans. As a health services researcher she conducts randomized controlled trials and observational studies targeting problems common in veterans such as chronic pain, opioid dependence and posttraumatic stress disorder and recently completed a trial testing a virtual worlds educational program to train primary care providers in PTSD assessment and management. She also actively mentors trainees, provides support for their research interests and seeks to involve them in one or more of the funded research studies listed below:

    1. wHOPE Study (Funded by NIH, PI). This is a multi-site pragmatic trial at 5 VA sites across the U.S. to compare a Whole Health Team approach to Primary Care Group Education and both are compared to Usual Care for veterans with chronic pain enrolled in VA healthcare.
    2. VOICE Study: (Funded by PCORI, Co-PI): A pragmatic effectiveness trial across 9 VA sites comparing an integrated pain team approach (modeled after the SFVAHCS Integrated Pain Team Clinic) vs. telephone collaborative management to improve pain and decrease opioid use among veterans.
    3. Virtual Worlds Training in PTSD for Primary Care Providers: A pilot RCT (Funded by DoD, PI): This pilot trial compared a novel Virtual Worlds training for primary care providers in PTSD assessment and management vs. a Web-Based Training
    4. Development of a Dietary Supplement Survey for Veterans (Funded by NIH, PI).We are engaged in participatory research to develop the first ever comprehensive survey of dietary supplement use among U.S. veterans.
    5. Non-funded research involves use of the VA Electronic Health Record to answer relevant and timely questions such as vitamin D deficiency predicting COVID-19-related hospitalization and mortality etc.

    Collapse Research 
    Collapse Research Activities and Funding
    Implementation of a Pragmatic Trial of Whole Health Team vs. Primary Care Group Education to Promote Non-Pharmacological Strategies to Improve Pain, Function and Quality of Life in Veterans
    NIH UH3AT009765Jan 20, 2020 - Dec 31, 2023
    Role: Principal Investigator
    Implementation of a Pragmatic Trial of Whole Health Team vs. Primary Care Group Education to Promote Non-Pharmacological Strategies to Improve Pain, Functioning, and Quality of Life in Veterans
    NIH UG3AT009765Sep 20, 2017 - Dec 31, 2019
    Role: Principal Investigator
    Comparative Effectiveness of Patient-Centered Strategies to Improve Pain Management and Opioid Safety for Veterans
    Patient Centered Outcomes Research Institute OPD-1511-33052Nov 1, 2016 - Oct 31, 2022
    Role: Co-Investigator
    Improving Care for Veterans with PTSD: Comparing Effectiveness of Medications to Augment First-line Pharmacotherapy
    Patient Centered Outcomes Research Institute 2015C2-150-31834Aug 1, 2016 - Jul 31, 2019
    Role: Co-Investigator
    Measurement Science QUERI Program
    NIH IP1HX002002Oct 1, 2015 - Sep 30, 2020
    Role: Co-Principal Investigator
    Evaluating the Implementation of the Integrated Pain Team: A Quality Improvement Project to Inform Scale-Up and Dissemination to Rural CBOCs in VISN 21
    Department of Veterns Affairs QUE 15-283Oct 1, 2015 - Sep 30, 2017
    Role: Principal Investigator
    Improving Access to Care for Warfighters: Virtual Worlds Technology to Enhance Primary Care Training in Posttraumatic Stress and Motivational Interviewing
    Department of Defense JW140067/ W81XWH-15-C-0088Sep 28, 2015 - Sep 27, 2019
    Role: Principal Investigator
    Chronic Effects of Neurotrauma Consortium: Epidemiology Project
    Departmet of Defense and Department of Veteran's Affairs W81XWH-12-PHTBI-CENCJan 1, 2015 - Dec 31, 2018
    Role: Co-Investigator
    Motivational Coaching to Enhance Mental Health Engagement in Rural Veterans
    CRE 12-083Aug 1, 2014 - Sep 30, 2018
    Role: Principal Investigator
    Development and Validation of a Perceived Access Measure
    Department of Veteran's Affairs CRE-12-300Jan 1, 2014 - Dec 31, 2018
    Role: Co-Investigator
    Improving Opioid Saftey in Veterans Using Collaborative Care and Decision Support
    NIH R34AT008319Sep 30, 2013 - Jun 30, 2017
    Role: Principal Investigator
    Neuropsychological Screening of OEF/OIF Veterans in VA Primary Care
    NIH I01HX000277Oct 1, 2010 - Sep 30, 2014
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials
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    Collapse In The News
    Collapse Faculty Mentoring
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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. How VA Whole Health Coaching Can Impact Veterans' Health and Quality of Life: A Mixed-Methods Pilot Program Evaluation. Glob Adv Health Med. 2021; 10:2164956121998283. Purcell N, Zamora K, Bertenthal D, Abadjian L, Tighe J, Seal KH. PMID: 33747639.
      View in: PubMed   Mentions:
    2. Women Veterans' Experiences with Integrated, Biopsychosocial Pain Care: A Qualitative Study. Pain Med. 2021 Feb 06. Nicosia FM, Gibson CJ, Purcell N, Zamora K, Tighe J, Seal KH. PMID: 33547797.
      View in: PubMed   Mentions:    Fields:    
    3. Menopausal Hormone Therapy and Suicide in a National Sample of Midlife and Older Women Veterans. Med Care. 2021 Feb 01; 59:S70-S76. Gibson CJ, Li Y, Jasuja GK, Self KJ, Seal KH, Byers AL. PMID: 33438886.
      View in: PubMed   Mentions:    Fields:    
    4. A Pilot Trial of Collaborative Care with Motivational Interviewing to Reduce Opioid Risk and Improve Chronic Pain Management. Addiction. 2021 Jan 06. Borsari B, Li Y, Tighe J, Manuel JK, Gökbayrak NS, Delucchi K, Morasco BJ, Abadjian L, Cohen BE, Baxley C, Seal KH. PMID: 33405304.
      View in: PubMed   Mentions:    Fields:    
    5. Whole Health Options and Pain Education (wHOPE): A Pragmatic Trial Comparing Whole Health Team vs Primary Care Group Education to Promote Nonpharmacological Strategies to Improve Pain, Functioning, and Quality of Life in Veterans-Rationale, Methods, and Implementation. Pain Med. 2020 12 12; 21(Suppl 2):S91-S99. Seal KH, Becker WC, Murphy JL, Purcell N, Denneson LM, Morasco BJ, Martin AM, Reddy K, Iseghem TV, Krebs EE, Painter JM, Hagedorn H, Pyne JM, Hixon J, Maguen S, Neylan TC, Borsari B, DeRonne B, Gibson C, Matthias MS, Frank JW, Krishnaswamy A, Li Y, Bertenthal D, Chan A, Nunez A, McCamish N. PMID: 33313734.
      View in: PubMed   Mentions:    Fields:    
    6. Stakeholder Engagement in Pragmatic Clinical Trials: Emphasizing Relationships to Improve Pain Management Delivery and Outcomes. Pain Med. 2020 Dec 12; 21(Supplement_2):S13-S20. Bastian LA, Cohen SP, Katsovich L, Becker WC, Brummett BR, Burgess DJ, Crunkhorn AE, Denneson LM, Frank JW, Goertz C, Ilfeld B, Kanzler KE, Krishnaswamy A, LaChappelle K, Martino S, Mattocks K, McGeary CA, Reznik TE, Rhon DI, Salsbury SA, Seal KH, Semiatin AM, Shin MH, Simon CB, Teyhen DS, Zamora K, Kerns RD. PMID: 33313726.
      View in: PubMed   Mentions:    Fields:    
    7. Determining the median effective dose of prolonged exposure therapy for veterans with posttraumatic stress disorder. Behav Res Ther. 2020 12; 135:103756. Holder N, Shiner B, Li Y, Madden E, Neylan TC, Seal KH, Lujan C, Patterson OV, DuVall SL, Maguen S. PMID: 33157475.
      View in: PubMed   Mentions:    Fields:    
    8. Initial concurrent and convergent validity of the Perceived Access Inventory (PAI) for mental health services. Psychol Serv. 2020 Oct 08. Pyne JM, Kelly PA, Fischer EP, Miller CJ, Connolly SL, Wright P, Zamora K, Koenig CJ, Seal KH, Fortney JC. PMID: 33030947.
      View in: PubMed   Mentions:    Fields:    
    9. Tailored to Fit: How an Implementation Framework Can Support Pragmatic Pain Care Trial Adaptation for Diverse Veterans Affairs Clinical Settings. Med Care. 2020 09; 58 Suppl 2 9S:S80-S87. Purcell N, Becker WC, Zamora KA, McGrath SL, Hagedorn HJ, Fabian ER, McCamish N, Seal KH. PMID: 32826776.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    10. An Integrated Pain Team Model: Impact on Pain-Related Outcomes and Opioid Misuse in Patients with Chronic Pain. Pain Med. 2020 09 01; 21(9):1977-1984. Gibson CJ, Grasso J, Li Y, Purcell N, Tighe J, Zamora K, Nicosia F, Seal KH. PMID: 32100002.
      View in: PubMed   Mentions:    Fields:    
    11. How do gender and military sexual trauma impact PTSD symptoms in cognitive processing therapy and prolonged exposure? J Psychiatr Res. 2020 Nov; 130:89-96. Khan AJ, Holder N, Li Y, Shiner B, Madden E, Seal K, Neylan TC, Maguen S. PMID: 32798774.
      View in: PubMed   Mentions:    Fields:    
    12. Cognitive Processing Therapy for Veterans with Posttraumatic Stress Disorder: What is the Median Effective Dose? J Affect Disord. 2020 08 01; 273:425-433. Holder N, Shiner B, Li Y, Madden E, Neylan TC, Seal KH, Lujan C, Patterson OV, DuVall SL, Maguen S. PMID: 32560937.
      View in: PubMed   Mentions:    Fields:    
    13. Factors associated with PTSD symptom improvement among Iraq and Afghanistan veterans receiving evidenced-based psychotherapy. J Affect Disord. 2020 08 01; 273:1-7. Maguen S, Holder N, Li Y, Madden E, Neylan TC, Seal KH, Lujan C, Patterson OV, DuVall SL, Shiner B. PMID: 32421589.
      View in: PubMed   Mentions:    Fields:    
    14. Screening for CKD To Improve Processes of Care among Nondiabetic Veterans with Hypertension: A Pragmatic Cluster-Randomized Trial. Clin J Am Soc Nephrol. 2020 02 07; 15(2):174-181. Peralta CA, Frigaard M, Rolon L, Seal K, Tuot D, Senyak J, Lo L, Powe N, Scherzer R, Chao S, Chiao P, Lui K, Shlipak MG, Rubinsky AD. PMID: 32034070.
      View in: PubMed   Mentions:    Fields:    
    15. Evidence-based psychotherapy trends among posttraumatic stress disorder patients in a national healthcare system, 2001-2014. Depress Anxiety. 2020 04; 37(4):356-364. Maguen S, Holder N, Madden E, Li Y, Seal KH, Neylan TC, Lujan C, Patterson OV, DuVall SL, Shiner B. PMID: 31850650.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    16. Opioid Reduction and Risk Mitigation in VA Primary Care: Outcomes from the Integrated Pain Team Initiative. J Gen Intern Med. 2020 Apr; 35(4):1238-1244. Seal KH, Rife T, Li Y, Gibson C, Tighe J. PMID: 31848861.
      View in: PubMed   Mentions:    Fields:    
    17. A national study of TBI and risk of suicide and unintended death by overdose and firearms. Brain Inj. 2020 02 23; 34(3):328-334. Byers AL, Li Y, Barnes DE, Seal KH, Boscardin WJ, Yaffe K. PMID: 31822136.
      View in: PubMed   Mentions: 1     Fields:    
    18. Posttraumatic Stress Disorder Severity and Insomnia-Related Sleep Disturbances: Longitudinal Associations in a Large, Gender-Balanced Cohort of Combat-Exposed Veterans. J Trauma Stress. 2019 12; 32(6):936-945. Rosen RC, Cikesh B, Fang S, Trachtenberg FL, Seal KH, Magnavita AM, Bovin MJ, Green JD, Bliwise DL, Marx BP, Keane TM. PMID: 31800135.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    19. Menopausal Symptoms and Higher Risk Opioid Prescribing in a National Sample of Women Veterans with Chronic Pain. J Gen Intern Med. 2019 10; 34(10):2159-2166. Gibson CJ, Li Y, Huang AJ, Rife T, Seal KH. PMID: 31414358.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    20. Timing of evidence-based psychotherapy for posttraumatic stress disorder initiation among Iraq and Afghanistan war veterans in the Veterans Health Administration. Psychol Trauma. 2020 Mar; 12(3):260-271. Holder N, Shiner B, Li Y, Madden E, Neylan TC, Seal KH, Lujan C, Patterson OV, DuVall SL, Maguen S. PMID: 31343206.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    21. Development of a Perceived Access Inventory for Community Care Mental Healthcare Services for Veterans. Mil Med. 2019 07 01; 184(7-8):e301-e308. Pyne JM, Kelly PA, Fischer EP, Miller CJ, Wright P, Zamora K, Koenig CJ, Stanley R, Seal K, Fortney JC. PMID: 30690462.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    22. Menopause symptoms and chronic pain in a national sample of midlife women veterans. Menopause. 2019 07; 26(7):708-713. Gibson CJ, Li Y, Bertenthal D, Huang AJ, Seal KH. PMID: 30839364.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    23. Beyond the Revolving Door: Long-Term Lived Experience of Eating Disorders and Specialist Service Provision. Qual Health Res. 2019 12; 29(14):2070-2083. Joyce C, Greasley P, Weatherhead S, Seal K. PMID: 31165677.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    24. Patient Experiences With Integrated Pain Care: A Qualitative Evaluation of One VA's Biopsychosocial Approach to Chronic Pain Treatment and Opioid Safety. Glob Adv Health Med. 2019; 8:2164956119838845. Purcell N, Zamora K, Gibson C, Tighe J, Chang J, Grasso J, Seal KH. PMID: 31041143.
      View in: PubMed   Mentions:
    25. Factors associated with completing evidence-based psychotherapy for PTSD among veterans in a national healthcare system. Psychiatry Res. 2019 04; 274:112-128. Maguen S, Li Y, Madden E, Seal KH, Neylan TC, Patterson OV, DuVall SL, Lujan C, Shiner B. PMID: 30784780.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    26. Optimizing pain treatment interventions (OPTI): A pilot randomized controlled trial of collaborative care to improve chronic pain management and opioid safety-Rationale, methods, and lessons learned. Contemp Clin Trials. 2019 02; 77:76-85. Seal KH, Borsari B, Tighe J, Cohen BE, Delucchi K, Morasco BJ, Li Y, Sachs E, Abadjian L, Watson EC, Manuel JK, Vella L, Trafton J, Midboe A. PMID: 30572163.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    27. Gender Differences in Cardiovascular Risk Related to Diabetes and Posttraumatic Stress Disorder. Am J Geriatr Psychiatry. 2018 12; 26(12):1268-1272. Gibson CJ, Li Y, Inslicht SS, Seal KH, Byers AL. PMID: 30314941.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    28. Association of Mild Traumatic Brain Injury With and Without Loss of Consciousness With Dementia in US Military Veterans. JAMA Neurol. 2018 09 01; 75(9):1055-1061. Barnes DE, Byers AL, Gardner RC, Seal KH, Boscardin WJ, Yaffe K. PMID: 29801145.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    29. The Integrated Pain Team: A Mixed-Methods Evaluation of the Impact of an Embedded Interdisciplinary Pain Care Intervention on Primary Care Team Satisfaction, Confidence, and Perceptions of Care Effectiveness. Pain Med. 2018 09 01; 19(9):1748-1763. Purcell N, Zamora K, Tighe J, Li Y, Douraghi M, Seal K. PMID: 29040715.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    30. Development of the Perceived Access Inventory: A patient-centered measure of access to mental health care. Psychol Serv. 2020 Feb; 17(1):13-24. Pyne JM, Kelly PA, Fischer EP, Miller CJ, Wright P, Zamora K, Koenig CJ, Stanley R, Seal K, Burgess JF, Fortney JC. PMID: 30024190.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    31. Do postconcussive symptoms from traumatic brain injury in combat veterans predict risk for receiving opioid therapy for chronic pain? Brain Inj. 2018; 32(10):1188-1196. Bertenthal D, Yaffe K, Barnes DE, Byers AL, Gibson CJ, Seal KH. PMID: 29985653.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    32. Traumatic Brain Injury and Receipt of Prescription Opioid Therapy for Chronic Pain in Iraq and Afghanistan Veterans: Do Clinical Practice Guidelines Matter? J Pain. 2018 08; 19(8):931-941. Seal KH, Bertenthal D, Barnes DE, Byers AL, Gibson CJ, Rife TL, Yaffe K, . PMID: 29597083.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    33. Prospective Examination of Early Associations of Iraq War Zone Deployment, Combat Severity, and Posttraumatic Stress Disorder with New Incident Medical Diagnoses. J Trauma Stress. 2018 02; 31(1):102-113. Brailey K, Mills MA, Marx BP, Proctor SP, Seal KH, Spiro A, Ulloa EW, Vasterling JJ. PMID: 29513919.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    34. The Association Between PTSD and Functional Outcome Is Mediated by Perception of Cognitive Problems Rather Than Objective Neuropsychological Test Performance. J Trauma Stress. 2017 10; 30(5):521-530. Samuelson KW, Abadjian L, Jordan JT, Bartel A, Vasterling J, Seal K. PMID: 29030878.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    35. Situating mental health work in place: Qualitative findings from interviews with Veterans in Southeastern Louisiana and Northern California. Health Place. 2017 Sep; 47:63-70. Abraham TH, Koenig CJ, Zamora K, Hill C, Uddo M, Kelly AP, Hamilton MF, Curran GM, Pyne JM, Seal KH. PMID: 28755653.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    36. Association of Traumatic Brain Injury With Chronic Pain in Iraq and Afghanistan Veterans: Effect of Comorbid Mental Health Conditions. Arch Phys Med Rehabil. 2017 08; 98(8):1636-1645. Seal KH, Bertenthal D, Barnes DE, Byers AL, Strigo I, Yaffe K, . PMID: 28455190.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    37. Implementation of a pragmatic randomized trial of screening for chronic kidney disease to improve care among non-diabetic hypertensive veterans. BMC Nephrol. 2017 04 12; 18(1):132. Peralta CA, Frigaard M, Rubinsky AD, Rolon L, Lo L, Voora S, Seal K, Tuot D, Chao S, Lui K, Chiao P, Powe N, Shlipak M. PMID: 28399844.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansPHPublic Health
    38. Managing Chronic Pain in Primary Care: It Really Does Take a Village. J Gen Intern Med. 2017 Aug; 32(8):931-934. Seal K, Becker W, Tighe J, Li Y, Rife T. PMID: 28337689.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    39. The mediating roles of coping, sleep, and anxiety motives in cannabis use and problems among returning veterans with PTSD and MDD. Psychol Addict Behav. 2016 Nov; 30(7):743-754. Metrik J, Jackson K, Bassett SS, Zvolensky MJ, Seal K, Borsari B. PMID: 27786514.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    40. Observational Evidence for Buprenorphine's Impact on Posttraumatic Stress Symptoms in Veterans With Chronic Pain and Opioid Use Disorder. J Clin Psychiatry. 2016 09; 77(9):1182-1188. Seal KH, Maguen S, Bertenthal D, Batki SL, Striebel J, Stein MB, Madden E, Neylan TC. PMID: 27035058.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    41. Pre-Implementation Strategies to Adapt and Implement a Veteran Peer Coaching Intervention to Improve Mental Health Treatment Engagement Among Rural Veterans. J Rural Health. 2016 09; 32(4):418-428. Koenig CJ, Abraham T, Zamora KA, Hill C, Kelly PA, Uddo M, Hamilton M, Pyne JM, Seal KH. PMID: 27509291.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    42. Sexual Health in Male and Female Iraq and Afghanistan U. S. War Veterans With and Without PTSD: Findings From the VALOR Cohort. J Trauma Stress. 2016 06; 29(3):229-36. Breyer BN, Fang SC, Seal KH, Ranganathan G, Marx BP, Keane TM, Rosen RC. PMID: 27128485.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    43. Assessing for mild TBI among Iraq and Afghanistan veterans: Outcomes of injury severity and neurological factors. Brain Inj. 2016; 30(3):287-94. Lau KM, Madden E, Neylan TC, Seal KH, Maguen S. PMID: 26910483.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    44. Association between mild traumatic brain injury and mental health problems and self-reported cognitive dysfunction in Iraq and Afghanistan Veterans. J Rehabil Res Dev. 2016; 53(2):185-98. Seal KH, Bertenthal D, Samuelson K, Maguen S, Kumar S, Vasterling JJ. PMID: 27148692.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    45. Race/ethnicity and gender differences in mental health diagnoses among Iraq and Afghanistan veterans. Psychiatry Res. 2015 Oct 30; 229(3):724-31. Koo KH, Hebenstreit CL, Madden E, Seal KH, Maguen S. PMID: 26282226.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    46. Suicide risk in Iraq and Afghanistan veterans with mental health problems in VA care. J Psychiatr Res. 2015 Sep; 68:120-4. Maguen S, Madden E, Cohen BE, Bertenthal D, Neylan TC, Seal KH. PMID: 26228410.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    47. Antipsychotic prescriptions in Iraq and Afghanistan veterans with posttraumatic stress disorder in Department of Veterans Affairs healthcare, 2007-2012. J Clin Psychiatry. 2015 Apr; 76(4):406-12. Cohen BE, Shi Y, Neylan TC, Maguen S, Seal KH. PMID: 25845036.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    48. Timing of mental health treatment and PTSD Symptom improvement among Iraq and Afghanistan veterans. Psychiatr Serv. 2014 Dec 01; 65(12):1414-9. Maguen S, Madden E, Neylan TC, Cohen BE, Bertenthal D, Seal KH. PMID: 25082217.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    49. Sex differences in chronic pain management practices for patients receiving opioids from the Veterans Health Administration. Pain Med. 2015 Jan; 16(1):112-8. Oliva EM, Midboe AM, Lewis ET, Henderson PT, Dalton AL, Im JJ, Seal K, Paik MC, Trafton JA. PMID: 25039721.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    50. Elevated risk for autoimmune disorders in iraq and afghanistan veterans with posttraumatic stress disorder. Biol Psychiatry. 2015 Feb 15; 77(4):365-74. O'Donovan A, Cohen BE, Seal KH, Bertenthal D, Margaretten M, Nishimi K, Neylan TC. PMID: 25104173.
      View in: PubMed   Mentions: 44     Fields:    Translation:Humans
    51. Facilitating culture-centered communication between health care providers and veterans transitioning from military deployment to civilian life. Patient Educ Couns. 2014 Jun; 95(3):414-20. Koenig CJ, Maguen S, Monroy JD, Mayott L, Seal KH. PMID: 24742536.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    52. Web-based PTSD training for primary care providers: a pilot study. Psychol Serv. 2014 May; 11(2):153-61. Samuelson KW, Koenig CJ, McCamish N, Choucroun G, Tarasovsky G, Bertenthal D, Seal KH. PMID: 24364595.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    53. Lower urinary tract dysfunction in male Iraq and Afghanistan war veterans: association with mental health disorders: a population-based cohort study. Urology. 2014 Feb; 83(2):312-9. Breyer BN, Cohen BE, Bertenthal D, Rosen RC, Neylan TC, Seal KH. PMID: 24149111.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    54. Follow-up care for alcohol misuse among OEF/OIF veterans with and without alcohol use disorders and posttraumatic stress disorder. J Subst Abuse Treat. 2013 Nov-Dec; 45(5):409-15. Grossbard JR, Hawkins EJ, Lapham GT, Williams EC, Rubinsky AD, Simpson TL, Seal KH, Kivlahan DR, Bradley KA. PMID: 23906670.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    55. Service utilization among Iraq and Afghanistan veterans screening positive for traumatic brain injury. J Neurotrauma. 2013 Jul 01; 30(13):1123-8. Maguen S, Madden E, Lau KM, Seal KH. PMID: 23327186.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    56. The relationship between body mass index and mental health among Iraq and Afghanistan veterans. J Gen Intern Med. 2013 Jul; 28 Suppl 2:S563-70. Maguen S, Madden E, Cohen B, Bertenthal D, Neylan T, Talbot L, Grunfeld C, Seal K. PMID: 23807066.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    57. Preventing the pain of PTSD. Sci Transl Med. 2013 Jun 05; 5(188):188fs22. Seal KH, Stein MB. PMID: 23740896.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    58. Relationships among veteran status, gender, and key health indicators in a national young adult sample. Psychiatr Serv. 2013 Jun; 64(6):547-53. Grossbard JR, Lehavot K, Hoerster KD, Jakupcak M, Seal KH, Simpson TL. PMID: 23450338.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    59. Sexual dysfunction in male Iraq and Afghanistan war veterans: association with posttraumatic stress disorder and other combat-related mental health disorders: a population-based cohort study. J Sex Med. 2014 Jan; 11(1):75-83. Breyer BN, Cohen BE, Bertenthal D, Rosen RC, Neylan TC, Seal KH. PMID: 23679562.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    60. Association of mental health problems with gastrointestinal disorders in Iraq and Afghanistan veterans. Depress Anxiety. 2014 Feb; 31(2):160-5. Maguen S, Madden E, Cohen B, Bertenthal D, Seal K. PMID: 23494973.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    61. Readiness for change predicts VA Mental Healthcare utilization among Iraq and Afghanistan war veterans. J Trauma Stress. 2013 Feb; 26(1):165-8. Jakupcak M, Hoerster KD, Blais RK, Malte CA, Hunt S, Seal K. PMID: 23319359.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansPHPublic Health
    62. Time to treatment among veterans of conflicts in Iraq and Afghanistan with psychiatric diagnoses. Psychiatr Serv. 2012 Dec; 63(12):1206-12. Maguen S, Madden E, Cohen BE, Bertenthal D, Seal KH. PMID: 23070131.
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    63. Reproductive and other health outcomes in Iraq and Afghanistan women veterans using VA health care: association with mental health diagnoses. Womens Health Issues. 2012 Sep; 22(5):e461-71. Cohen BE, Maguen S, Bertenthal D, Shi Y, Jacoby V, Seal KH. PMID: 22944901.
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    64. Passing the baton: a grounded practical theory of handoff communication between multidisciplinary providers in two Department of Veterans Affairs outpatient settings. J Gen Intern Med. 2013 Jan; 28(1):41-50. Koenig CJ, Maguen S, Daley A, Cohen G, Seal KH. PMID: 22868947.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    65. Factors associated with completing comprehensive traumatic brain injury evaluation. Mil Med. 2012 Jul; 177(7):797-803. Maguen S, Lau KM, Madden E, Seal K. PMID: 22808886.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health
    66. Eating disorders and psychiatric comorbidity among Iraq and Afghanistan veterans. Womens Health Issues. 2012 Jul-Aug; 22(4):e403-6. Maguen S, Cohen B, Cohen G, Madden E, Bertenthal D, Seal K. PMID: 22749199.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    67. Post deployment care for returning combat veterans. J Gen Intern Med. 2012 Sep; 27(9):1200-9. Spelman JF, Hunt SC, Seal KH, Burgo-Black AL. PMID: 22648608.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansPHPublic Health
    68. A randomized controlled trial of telephone motivational interviewing to enhance mental health treatment engagement in Iraq and Afghanistan veterans. Gen Hosp Psychiatry. 2012 Sep-Oct; 34(5):450-9. Seal KH, Abadjian L, McCamish N, Shi Y, Tarasovsky G, Weingardt K. PMID: 22632925.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    69. Association of mental health disorders with prescription opioids and high-risk opioid use in US veterans of Iraq and Afghanistan. JAMA. 2012 Mar 07; 307(9):940-7. Seal KH, Shi Y, Cohen G, Cohen BE, Maguen S, Krebs EE, Neylan TC. PMID: 22396516.
      View in: PubMed   Mentions: 138     Fields:    Translation:Humans
    70. Gender differences in health service utilization among Iraq and Afghanistan veterans with posttraumatic stress disorder. J Womens Health (Larchmt). 2012 Jun; 21(6):666-73. Maguen S, Cohen B, Cohen G, Madden E, Bertenthal D, Seal K. PMID: 22313026.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    71. The impact of head injury mechanism on mental health symptoms in veterans: do number and type of exposures matter? J Trauma Stress. 2012 Feb; 25(1):3-9. Maguen S, Madden E, Lau KM, Seal K. PMID: 22354503.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansPHPublic Health
    72. Relationship of screen-based symptoms for mild traumatic brain injury and mental health problems in Iraq and Afghanistan veterans: Distinct or overlapping symptoms? J Rehabil Res Dev. 2012; 49(7):1115-26. Maguen S, Lau KM, Madden E, Seal K. PMID: 23341283.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansPHPublic Health
    73. Gender differences in military sexual trauma and mental health diagnoses among Iraq and Afghanistan veterans with posttraumatic stress disorder. Womens Health Issues. 2012 Jan-Feb; 22(1):e61-6. Maguen S, Cohen B, Ren L, Bosch J, Kimerling R, Seal K. PMID: 21907590.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    74. Reducing barriers to mental health and social services for Iraq and Afghanistan veterans: outcomes of an integrated primary care clinic. J Gen Intern Med. 2011 Oct; 26(10):1160-7. Seal KH, Cohen G, Bertenthal D, Cohen BE, Maguen S, Daley A. PMID: 21647750.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    75. Substance use disorders in Iraq and Afghanistan veterans in VA healthcare, 2001-2010: Implications for screening, diagnosis and treatment. Drug Alcohol Depend. 2011 Jul 01; 116(1-3):93-101. Seal KH, Cohen G, Waldrop A, Cohen BE, Maguen S, Ren L. PMID: 21277712.
      View in: PubMed   Mentions: 107     Fields:    Translation:Humans
    76. Gender differences in mental health diagnoses among Iraq and Afghanistan veterans enrolled in veterans affairs health care. Am J Public Health. 2010 Dec; 100(12):2450-6. Maguen S, Ren L, Bosch JO, Marmar CR, Seal KH. PMID: 20966380.
      View in: PubMed   Mentions: 39     Fields:    Translation:Humans
    77. The impact of reported direct and indirect killing on mental health symptoms in Iraq war veterans. J Trauma Stress. 2010 Feb; 23(1):86-90. Maguen S, Lucenko BA, Reger MA, Gahm GA, Litz BT, Seal KH, Knight SJ, Marmar CR. PMID: 20104592.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansPHPublic Health
    78. VA mental health services utilization in Iraq and Afghanistan veterans in the first year of receiving new mental health diagnoses. J Trauma Stress. 2010 Feb; 23(1):5-16. Seal KH, Maguen S, Cohen B, Gima KS, Metzler TJ, Ren L, Bertenthal D, Marmar CR. PMID: 20146392.
      View in: PubMed   Mentions: 83     Fields:    Translation:Humans
    79. The impact of killing in war on mental health symptoms and related functioning. J Trauma Stress. 2009 Oct; 22(5):435-43. Maguen S, Metzler TJ, Litz BT, Seal KH, Knight SJ, Marmar CR. PMID: 19842160.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    80. Mental health diagnoses and utilization of VA non-mental health medical services among returning Iraq and Afghanistan veterans. J Gen Intern Med. 2010 Jan; 25(1):18-24. Cohen BE, Gima K, Bertenthal D, Kim S, Marmar CR, Seal KH. PMID: 19787409.
      View in: PubMed   Mentions: 47     Fields:    Translation:Humans
    81. Association of cardiovascular risk factors with mental health diagnoses in Iraq and Afghanistan war veterans using VA health care. JAMA. 2009 Aug 05; 302(5):489-92. Cohen BE, Marmar C, Ren L, Bertenthal D, Seal KH. PMID: 19654382.
      View in: PubMed   Mentions: 48     Fields:    Translation:Humans
    82. Trends and risk factors for mental health diagnoses among Iraq and Afghanistan veterans using Department of Veterans Affairs health care, 2002-2008. Am J Public Health. 2009 Sep; 99(9):1651-8. Seal KH, Metzler TJ, Gima KS, Bertenthal D, Maguen S, Marmar CR. PMID: 19608954.
      View in: PubMed   Mentions: 148     Fields:    Translation:Humans
    83. Association of hepatitis C virus seropositivity with inflammatory markers and heart failure in persons with coronary heart disease: data from the Heart and Soul study. J Card Fail. 2009 Jun; 15(5):451-6. Tsui JI, Whooley MA, Monto A, Seal K, Tien PC, Shlipak M. PMID: 19477406.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    84. Economic evaluation of delivering hepatitis B vaccine to injection drug users. Am J Prev Med. 2008 Jul; 35(1):25-32. Hu Y, Grau LE, Scott G, Seal KH, Marshall PA, Singer M, Heimer R. PMID: 18541174.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    85. What lies between hypomania and bipolar disorder? A qualitative analysis of 12 non-treatment-seeking people with a history of hypomanic experiences and no history of major depression. Psychol Psychother. 2008 Mar; 81(Pt 1):33-53. Seal K, Mansell W, Mannion H. PMID: 18396518.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    86. Getting beyond "Don't ask; don't tell": an evaluation of US Veterans Administration postdeployment mental health screening of veterans returning from Iraq and Afghanistan. Am J Public Health. 2008 Apr; 98(4):714-20. Seal KH, Bertenthal D, Maguen S, Gima K, Chu A, Marmar CR. PMID: 18309130.
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    87. The association of human immunodeficiency virus infection with spontaneously resolved hepatitis C virus infection and level of viremia among injection drug users. Dig Dis Sci. 2007 Dec; 52(12):3423-30. Seal KH, Monto A, Dove L, Shen H, Vittinghoff E, Tracy D, Miller E, Lau E, Wright TL. PMID: 17443407.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    88. Bringing the war back home: mental health disorders among 103,788 US veterans returning from Iraq and Afghanistan seen at Department of Veterans Affairs facilities. Arch Intern Med. 2007 Mar 12; 167(5):476-82. Seal KH, Bertenthal D, Miner CR, Sen S, Marmar C. PMID: 17353495.
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    89. Hepatitis C treatment candidacy and outcomes among 4318 US veterans with chronic hepatitis C virus infection: does a history of injection drug use matter? J Clin Gastroenterol. 2007 Feb; 41(2):199-205. Seal KH, Currie SL, Shen H, Anand BS, Bini EJ, Brau N, Jeffers L, Wright TL. PMID: 17245220.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    90. Hepatitis C and hospital outcomes in patients admitted with alcohol-related problems. J Hepatol. 2006 Feb; 44(2):262-6. Tsui JI, Pletcher MJ, Vittinghoff E, Seal K, Gonzales R. PMID: 16226823.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    91. Naloxone distribution and cardiopulmonary resuscitation training for injection drug users to prevent heroin overdose death: a pilot intervention study. J Urban Health. 2005 Jun; 82(2):303-11. Seal KH, Thawley R, Gee L, Bamberger J, Kral AH, Ciccarone D, Downing M, Edlin BR. PMID: 15872192.
      View in: PubMed   Mentions: 77     Fields:    Translation:Humans
    92. A randomized controlled trial of monetary incentives vs. outreach to enhance adherence to the hepatitis B vaccine series among injection drug users. Drug Alcohol Depend. 2003 Aug 20; 71(2):127-31. Seal KH, Kral AH, Lorvick J, McNees A, Gee L, Edlin BR. PMID: 12927650.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCTClinical Trials
    93. Prevalence of SEN viruses among injection drug users in the San Francisco Bay area. J Infect Dis. 2003 Jul 01; 188(1):13-8. Pfeiffer RM, Tanaka Y, Yeo AE, Umemura T, Seal KH, Shih JW, Alter HJ, Edlin BR, O'Brien TR. PMID: 12825166.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    94. Attitudes about prescribing take-home naloxone to injection drug users for the management of heroin overdose: a survey of street-recruited injectors in the San Francisco Bay Area. J Urban Health. 2003 Jun; 80(2):291-301. Seal KH, Downing M, Kral AH, Singleton-Banks S, Hammond JP, Lorvick J, Ciccarone D, Edlin BR. PMID: 12791805.
      View in: PubMed   Mentions: 34     Fields:    Translation:Humans
    95. Seroprevalence of human herpesvirus 8 among injection drug users in San Francisco. J Infect Dis. 2003 Mar 15; 187(6):974-81. Atkinson J, Edlin BR, Engels EA, Kral AH, Seal K, Gamache CJ, Whitby D, O'Brien TR. PMID: 12660944.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    96. Predictors and prevention of nonfatal overdose among street-recruited injection heroin users in the San Francisco Bay Area, 1998-1999. Am J Public Health. 2001 Nov; 91(11):1842-6. Seal KH, Kral AH, Gee L, Moore LD, Bluthenthal RN, Lorvick J, Edlin BR. PMID: 11684613.
      View in: PubMed   Mentions: 78     Fields:    Translation:Humans
    97. Trends in HIV seroprevalence and risk among gay and bisexual men who inject drugs in San Francisco, 1988 to 2000. . 2001 Nov 01; 28(3):264-9. Bluthenthal RN, Kral AH, Gee L, Lorvick J, Moore L, Seal K, Edlin BR. PMID: 11694834.
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    98. Is it justifiable to withhold treatment for hepatitis C from illicit-drug users? N Engl J Med. 2001 Jul 19; 345(3):211-5. Edlin BR, Seal KH, Lorvick J, Kral AH, Ciccarone DH, Moore LD, Lo B. PMID: 11463019.
      View in: PubMed   Mentions: 54     Fields:    Translation:Humans
    99. Overdosing among young injection drug users in San Francisco. Addict Behav. 2001 May-Jun; 26(3):453-60. Ochoa KC, Hahn JA, Seal KH, Moss AR. PMID: 11436937.
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    100. Prevalence and duration of hepatitis C among injection drug users in San Francisco, Calif. Am J Public Health. 2001 Jan; 91(1):46-7. Lorvick J, Kral AH, Seal K, Gee L, Edlin BR. PMID: 11189823.
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    101. Risk of hepatitis B infection among young injection drug users in San Francisco: opportunities for intervention. West J Med. 2000 Jan; 172(1):16-20. Seal KH, Ochoa KC, Hahn JA, Tulsky JP, Edlin BR, Moss AR. PMID: 10695436.
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    102. Prospective examination of early associations of Iraq warzone deployment, combat severity, and PTSD with new incident medical diagnoses. Journal of Traumatic Stress. Brailey, K, Mills, MA, Marx, BP, Proctor, SP, Seal, KH, Spiro, A, III, Ulloa, E. W., & Vasterling, J. J. View Publication.
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