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Karen Seal, MD

TitleProfessor
SchoolUCSF School of Medicine
DepartmentMedicine
Address4150 Clement St.
San Francisco CA 94121
Phone415-221-4810
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    Collapse Biography 
    Collapse Education and Training
    University of California, San FranciscoResidency Internal Medicine

    Collapse Research 
    Collapse Research Activities and Funding
    Implementation of a Pragmatic Trial of Whole Health Team vs. Primary Care Group Education to Promote Non-Pharmacological Strategies to Improve Pain, Functioning, and Quality of Life in Veterans
    NIH/NCCIH UG3AT009765Sep 20, 2017 - Aug 31, 2019
    Role: Principal Investigator
    Improving Opioid Saftey in Veterans Using Collaborative Care and Decision Support
    NIH/NCCIH R34AT008319Sep 30, 2013 - Jun 30, 2016
    Role: Principal Investigator
    Neuropsychological Screening of OEF/OIF Veterans in VA Primary Care
    VA I01HX000277Oct 1, 2010 - Mar 31, 2015
    Role: Principal Investigator
    RANDOMIZED HEPATITIS B VACCINE DELIVERY TRIAL FOR IDUS
    NIH/NIDA R01DA011860May 15, 1998 - Apr 30, 2001
    Role: Principal Investigator

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Abraham TH, Koenig CJ, Zamora K, Hill C, Uddo M, Kelly AP, Hamilton MF, Curran GM, Pyne JM, Seal K. Situating mental health work in place: Qualitative findings from interviews with Veterans in Southeastern Louisiana and Northern California. Health Place. 2017 Sep; 47:63-70. PMID: 28755653.
      View in: PubMed
    2. Seal K, Bertenthal D, Barnes DE, Byers AL, Strigo I, Yaffe K. Association of Traumatic Brain Injury With Chronic Pain in Iraq and Afghanistan Veterans: Effect of Comorbid Mental Health Conditions. Arch Phys Med Rehabil. 2017 Aug; 98(8):1636-1645. PMID: 28455190.
      View in: PubMed
    3. Metrik J, Jackson K, Bassett SS, Zvolensky MJ, Seal K, Borsari B. The mediating roles of coping, sleep, and anxiety motives in cannabis use and problems among returning veterans with PTSD and MDD. Psychol Addict Behav. 2016 Nov; 30(7):743-754. PMID: 27786514.
      View in: PubMed
    4. Seal K, Maguen S, Bertenthal D, Batki SL, Striebel J, Stein MB, Madden E, Neylan TC. Observational Evidence for Buprenorphine's Impact on Posttraumatic Stress Symptoms in Veterans With Chronic Pain and Opioid Use Disorder. J Clin Psychiatry. 2016 Sep; 77(9):1182-1188. PMID: 27035058.
      View in: PubMed
    5. Koenig CJ, Abraham T, Zamora KA, Hill C, Kelly PA, Uddo M, Hamilton M, Pyne JM, Seal K. Pre-Implementation Strategies to Adapt and Implement a Veteran Peer Coaching Intervention to Improve Mental Health Treatment Engagement Among Rural Veterans. J Rural Health. 2016 Sep; 32(4):418-428. PMID: 27509291.
      View in: PubMed
    6. Breyer BN, Fang SC, Seal K, Ranganathan G, Marx BP, Keane TM, Rosen RC. Sexual Health in Male and Female Iraq and Afghanistan U. S. War Veterans With and Without PTSD: Findings From the VALOR Cohort. J Trauma Stress. 2016 Jun; 29(3):229-36. PMID: 27128485; PMCID: PMC4899252.
    7. Lau KM, Madden E, Neylan TC, Seal K, Maguen S. Assessing for mild TBI among Iraq and Afghanistan veterans: Outcomes of injury severity and neurological factors. Brain Inj. 2016; 30(3):287-94. PMID: 26910483.
      View in: PubMed
    8. Seal K, Bertenthal D, Samuelson K, Maguen S, Kumar S, Vasterling JJ. Association between mild traumatic brain injury and mental health problems and self-reported cognitive dysfunction in Iraq and Afghanistan Veterans. J Rehabil Res Dev. 2016; 53(2):185-98. PMID: 27148692.
      View in: PubMed
    9. Koo KH, Hebenstreit CL, Madden E, Seal K, Maguen S. Race/ethnicity and gender differences in mental health diagnoses among Iraq and Afghanistan veterans. Psychiatry Res. 2015 Oct 30; 229(3):724-31. PMID: 26282226.
      View in: PubMed
    10. Maguen S, Madden E, Cohen BE, Bertenthal D, Neylan TC, Seal K. Suicide risk in Iraq and Afghanistan veterans with mental health problems in VA care. J Psychiatr Res. 2015 Sep; 68:120-4. PMID: 26228410.
      View in: PubMed
    11. Cohen BE, Shi Y, Neylan TC, Maguen S, Seal K. Antipsychotic prescriptions in Iraq and Afghanistan veterans with posttraumatic stress disorder in Department of Veterans Affairs healthcare, 2007-2012. J Clin Psychiatry. 2015 Apr; 76(4):406-12. PMID: 25845036.
      View in: PubMed
    12. Maguen S, Madden E, Neylan TC, Cohen BE, Bertenthal D, Seal K. Timing of mental health treatment and PTSD Symptom improvement among Iraq and Afghanistan veterans. Psychiatr Serv. 2014 Dec 01; 65(12):1414-9. PMID: 25082217.
      View in: PubMed
    13. Oliva EM, Midboe AM, Lewis ET, Henderson PT, Dalton AL, Im JJ, Seal K, Paik MC, Trafton JA. Sex differences in chronic pain management practices for patients receiving opioids from the Veterans Health Administration. Pain Med. 2015 Jan; 16(1):112-8. PMID: 25039721.
      View in: PubMed
    14. O'Donovan A, Cohen BE, Seal K, Bertenthal D, Margaretten M, Nishimi K, Neylan TC. Elevated risk for autoimmune disorders in iraq and afghanistan veterans with posttraumatic stress disorder. Biol Psychiatry. 2015 Feb 15; 77(4):365-74. PMID: 25104173; PMCID: PMC4277929.
    15. Koenig CJ, Maguen S, Monroy JD, Mayott L, Seal K. Facilitating culture-centered communication between health care providers and veterans transitioning from military deployment to civilian life. Patient Educ Couns. 2014 Jun; 95(3):414-20. PMID: 24742536.
      View in: PubMed
    16. Samuelson KW, Koenig CJ, McCamish N, Choucroun G, Tarasovsky G, Bertenthal D, Seal K. Web-based PTSD training for primary care providers: a pilot study. Psychol Serv. 2014 May; 11(2):153-61. PMID: 24364595.
      View in: PubMed
    17. Breyer BN, Cohen BE, Bertenthal D, Rosen RC, Neylan TC, Seal K. Lower urinary tract dysfunction in male Iraq and Afghanistan war veterans: association with mental health disorders: a population-based cohort study. Urology. 2014 Feb; 83(2):312-9. PMID: 24149111; PMCID: PMC4123450.
    18. Grossbard JR, Hawkins EJ, Lapham GT, Williams EC, Rubinsky AD, Simpson TL, Seal K, Kivlahan DR, Bradley KA. Follow-up care for alcohol misuse among OEF/OIF veterans with and without alcohol use disorders and posttraumatic stress disorder. J Subst Abuse Treat. 2013 Nov-Dec; 45(5):409-15. PMID: 23906670.
      View in: PubMed
    19. Maguen S, Madden E, Lau KM, Seal K. Service utilization among Iraq and Afghanistan veterans screening positive for traumatic brain injury. J Neurotrauma. 2013 Jul 01; 30(13):1123-8. PMID: 23327186.
      View in: PubMed
    20. Maguen S, Madden E, Cohen B, Bertenthal D, Neylan T, Talbot L, Grunfeld C, Seal K. The relationship between body mass index and mental health among Iraq and Afghanistan veterans. J Gen Intern Med. 2013 Jul; 28 Suppl 2:S563-70. PMID: 23807066; PMCID: PMC3695271.
    21. Seal K, Stein MB. Preventing the pain of PTSD. Sci Transl Med. 2013 Jun 05; 5(188):188fs22. PMID: 23740896.
      View in: PubMed
    22. Grossbard JR, Lehavot K, Hoerster KD, Jakupcak M, Seal K, Simpson TL. Relationships among veteran status, gender, and key health indicators in a national young adult sample. Psychiatr Serv. 2013 Jun; 64(6):547-53. PMID: 23450338.
      View in: PubMed
    23. Breyer BN, Cohen BE, Bertenthal D, Rosen RC, Neylan TC, Seal K. Sexual dysfunction in male Iraq and Afghanistan war veterans: association with posttraumatic stress disorder and other combat-related mental health disorders: a population-based cohort study. J Sex Med. 2014 Jan; 11(1):75-83. PMID: 23679562; PMCID: PMC4081408.
    24. Maguen S, Madden E, Cohen B, Bertenthal D, Seal K. Association of mental health problems with gastrointestinal disorders in Iraq and Afghanistan veterans. Depress Anxiety. 2014 Feb; 31(2):160-5. PMID: 23494973.
      View in: PubMed
    25. Jakupcak M, Hoerster KD, Blais RK, Malte CA, Hunt S, Seal K. Readiness for change predicts VA Mental Healthcare utilization among Iraq and Afghanistan war veterans. J Trauma Stress. 2013 Feb; 26(1):165-8. PMID: 23319359.
      View in: PubMed
    26. Maguen S, Madden E, Cohen BE, Bertenthal D, Seal K. Time to treatment among veterans of conflicts in Iraq and Afghanistan with psychiatric diagnoses. Psychiatr Serv. 2012 Dec; 63(12):1206-12. PMID: 23070131.
      View in: PubMed
    27. Cohen BE, Maguen S, Bertenthal D, Shi Y, Jacoby V, Seal K. Reproductive and other health outcomes in Iraq and Afghanistan women veterans using VA health care: association with mental health diagnoses. Womens Health Issues. 2012 Sep; 22(5):e461-71. PMID: 22944901; PMCID: PMC4631402.
    28. Koenig CJ, Maguen S, Daley A, Cohen G, Seal K. Passing the baton: a grounded practical theory of handoff communication between multidisciplinary providers in two Department of Veterans Affairs outpatient settings. J Gen Intern Med. 2013 Jan; 28(1):41-50. PMID: 22868947; PMCID: PMC3539021.
    29. Maguen S, Lau KM, Madden E, Seal K. Factors associated with completing comprehensive traumatic brain injury evaluation. Mil Med. 2012 Jul; 177(7):797-803. PMID: 22808886.
      View in: PubMed
    30. Maguen S, Cohen B, Cohen G, Madden E, Bertenthal D, Seal K. Eating disorders and psychiatric comorbidity among Iraq and Afghanistan veterans. Womens Health Issues. 2012 Jul-Aug; 22(4):e403-6. PMID: 22749199.
      View in: PubMed
    31. Spelman JF, Hunt SC, Seal K, Burgo-Black AL. Post deployment care for returning combat veterans. J Gen Intern Med. 2012 Sep; 27(9):1200-9. PMID: 22648608; PMCID: PMC3514997.
    32. Seal K, Abadjian L, McCamish N, Shi Y, Tarasovsky G, Weingardt K. A randomized controlled trial of telephone motivational interviewing to enhance mental health treatment engagement in Iraq and Afghanistan veterans. Gen Hosp Psychiatry. 2012 Sep-Oct; 34(5):450-9. PMID: 22632925.
      View in: PubMed
    33. Seal K, Shi Y, Cohen G, Cohen BE, Maguen S, Krebs EE, Neylan TC. Association of mental health disorders with prescription opioids and high-risk opioid use in US veterans of Iraq and Afghanistan. JAMA. 2012 Mar 07; 307(9):940-7. PMID: 22396516.
      View in: PubMed
    34. Maguen S, Cohen B, Cohen G, Madden E, Bertenthal D, Seal K. Gender differences in health service utilization among Iraq and Afghanistan veterans with posttraumatic stress disorder. J Womens Health (Larchmt). 2012 Jun; 21(6):666-73. PMID: 22313026; PMCID: PMC3366102.
    35. Maguen S, Madden E, Lau KM, Seal K. The impact of head injury mechanism on mental health symptoms in veterans: do number and type of exposures matter? J Trauma Stress. 2012 Feb; 25(1):3-9. PMID: 22354503.
      View in: PubMed
    36. Maguen S, Lau KM, Madden E, Seal K. Relationship of screen-based symptoms for mild traumatic brain injury and mental health problems in Iraq and Afghanistan veterans: Distinct or overlapping symptoms? J Rehabil Res Dev. 2012; 49(7):1115-26. PMID: 23341283.
      View in: PubMed
    37. Maguen S, Cohen B, Ren L, Bosch J, Kimerling R, Seal K. Gender differences in military sexual trauma and mental health diagnoses among Iraq and Afghanistan veterans with posttraumatic stress disorder. Womens Health Issues. 2012 Jan-Feb; 22(1):e61-6. PMID: 21907590.
      View in: PubMed
    38. Seal K, Cohen G, Bertenthal D, Cohen BE, Maguen S, Daley A. Reducing barriers to mental health and social services for Iraq and Afghanistan veterans: outcomes of an integrated primary care clinic. J Gen Intern Med. 2011 Oct; 26(10):1160-7. PMID: 21647750; PMCID: PMC3181313.
    39. Seal K, Cohen G, Waldrop A, Cohen BE, Maguen S, Ren L. Substance use disorders in Iraq and Afghanistan veterans in VA healthcare, 2001-2010: Implications for screening, diagnosis and treatment. Drug Alcohol Depend. 2011 Jul 01; 116(1-3):93-101. PMID: 21277712.
      View in: PubMed
    40. Maguen S, Ren L, Bosch JO, Marmar CR, Seal K. Gender differences in mental health diagnoses among Iraq and Afghanistan veterans enrolled in veterans affairs health care. Am J Public Health. 2010 Dec; 100(12):2450-6. PMID: 20966380; PMCID: PMC2978175.
    41. Maguen S, Lucenko BA, Reger MA, Gahm GA, Litz BT, Seal K, Knight SJ, Marmar CR. The impact of reported direct and indirect killing on mental health symptoms in Iraq war veterans. J Trauma Stress. 2010 Feb; 23(1):86-90. PMID: 20104592.
      View in: PubMed
    42. Seal K, Maguen S, Cohen B, Gima KS, Metzler TJ, Ren L, Bertenthal D, Marmar CR. VA mental health services utilization in Iraq and Afghanistan veterans in the first year of receiving new mental health diagnoses. J Trauma Stress. 2010 Feb; 23(1):5-16. PMID: 20146392.
      View in: PubMed
    43. Maguen S, Metzler TJ, Litz BT, Seal K, Knight SJ, Marmar CR. The impact of killing in war on mental health symptoms and related functioning. J Trauma Stress. 2009 Oct; 22(5):435-43. PMID: 19842160.
      View in: PubMed
    44. Cohen BE, Gima K, Bertenthal D, Kim S, Marmar CR, Seal K. Mental health diagnoses and utilization of VA non-mental health medical services among returning Iraq and Afghanistan veterans. J Gen Intern Med. 2010 Jan; 25(1):18-24. PMID: 19787409; PMCID: PMC2811589.
    45. Cohen BE, Marmar C, Ren L, Bertenthal D, Seal K. Association of cardiovascular risk factors with mental health diagnoses in Iraq and Afghanistan war veterans using VA health care. JAMA. 2009 Aug 05; 302(5):489-92. PMID: 19654382.
      View in: PubMed
    46. Seal K, Metzler TJ, Gima KS, Bertenthal D, Maguen S, Marmar CR. Trends and risk factors for mental health diagnoses among Iraq and Afghanistan veterans using Department of Veterans Affairs health care, 2002-2008. Am J Public Health. 2009 Sep; 99(9):1651-8. PMID: 19608954; PMCID: PMC2724454.
    47. Tsui JI, Whooley MA, Monto A, Seal K, Tien PC, Shlipak M. Association of hepatitis C virus seropositivity with inflammatory markers and heart failure in persons with coronary heart disease: data from the Heart and Soul study. J Card Fail. 2009 Jun; 15(5):451-6. PMID: 19477406; PMCID: PMC2782758.
    48. Hu Y, Grau LE, Scott G, Seal K, Marshall PA, Singer M, Heimer R. Economic evaluation of delivering hepatitis B vaccine to injection drug users. Am J Prev Med. 2008 Jul; 35(1):25-32. PMID: 18541174; PMCID: PMC2483306.
    49. Seal K, Mansell W, Mannion H. What lies between hypomania and bipolar disorder? A qualitative analysis of 12 non-treatment-seeking people with a history of hypomanic experiences and no history of major depression. Psychol Psychother. 2008 Mar; 81(Pt 1):33-53. PMID: 18396518.
      View in: PubMed
    50. Seal K, Bertenthal D, Maguen S, Gima K, Chu A, Marmar CR. Getting beyond "Don't ask; don't tell": an evaluation of US Veterans Administration postdeployment mental health screening of veterans returning from Iraq and Afghanistan. Am J Public Health. 2008 Apr; 98(4):714-20. PMID: 18309130; PMCID: PMC2377001.
    51. Seal K, Monto A, Dove L, Shen H, Vittinghoff E, Tracy D, Miller E, Lau E, Wright TL. The association of human immunodeficiency virus infection with spontaneously resolved hepatitis C virus infection and level of viremia among injection drug users. Dig Dis Sci. 2007 Dec; 52(12):3423-30. PMID: 17443407.
      View in: PubMed
    52. Seal K, Bertenthal D, Miner CR, Sen S, Marmar C. Bringing the war back home: mental health disorders among 103,788 US veterans returning from Iraq and Afghanistan seen at Department of Veterans Affairs facilities. Arch Intern Med. 2007 Mar 12; 167(5):476-82. PMID: 17353495.
      View in: PubMed
    53. Seal K, Currie SL, Shen H, Anand BS, Bini EJ, Brau N, Jeffers L, Wright TL. Hepatitis C treatment candidacy and outcomes among 4318 US veterans with chronic hepatitis C virus infection: does a history of injection drug use matter? J Clin Gastroenterol. 2007 Feb; 41(2):199-205. PMID: 17245220.
      View in: PubMed
    54. Tsui JI, Pletcher MJ, Vittinghoff E, Seal K, Gonzales R. Hepatitis C and hospital outcomes in patients admitted with alcohol-related problems. J Hepatol. 2006 Feb; 44(2):262-6. PMID: 16226823.
      View in: PubMed
    55. Seal K, Thawley R, Gee L, Bamberger J, Kral AH, Ciccarone D, Downing M, Edlin BR. Naloxone distribution and cardiopulmonary resuscitation training for injection drug users to prevent heroin overdose death: a pilot intervention study. J Urban Health. 2005 Jun; 82(2):303-11. PMID: 15872192; PMCID: PMC2570543.
    56. Seal K, Kral AH, Lorvick J, McNees A, Gee L, Edlin BR. A randomized controlled trial of monetary incentives vs. outreach to enhance adherence to the hepatitis B vaccine series among injection drug users. Drug Alcohol Depend. 2003 Aug 20; 71(2):127-31. PMID: 12927650.
      View in: PubMed
    57. Pfeiffer RM, Tanaka Y, Yeo AE, Umemura T, Seal K, Shih JW, Alter HJ, Edlin BR, O'Brien TR. Prevalence of SEN viruses among injection drug users in the San Francisco Bay area. J Infect Dis. 2003 Jul 01; 188(1):13-8. PMID: 12825166.
      View in: PubMed
    58. Seal K, Downing M, Kral AH, Singleton-Banks S, Hammond JP, Lorvick J, Ciccarone D, Edlin BR. Attitudes about prescribing take-home naloxone to injection drug users for the management of heroin overdose: a survey of street-recruited injectors in the San Francisco Bay Area. J Urban Health. 2003 Jun; 80(2):291-301. PMID: 12791805; PMCID: PMC3456285.
    59. Atkinson J, Edlin BR, Engels EA, Kral AH, Seal K, Gamache CJ, Whitby D, O'Brien TR. Seroprevalence of human herpesvirus 8 among injection drug users in San Francisco. J Infect Dis. 2003 Mar 15; 187(6):974-81. PMID: 12660944.
      View in: PubMed
    60. Seal K, Kral AH, Gee L, Moore LD, Bluthenthal RN, Lorvick J, Edlin BR. Predictors and prevention of nonfatal overdose among street-recruited injection heroin users in the San Francisco Bay Area, 1998-1999. Am J Public Health. 2001 Nov; 91(11):1842-6. PMID: 11684613; PMCID: PMC1446888.
    61. Bluthenthal RN, Kral AH, Gee L, Lorvick J, Moore L, Seal K, Edlin BR. Trends in HIV seroprevalence and risk among gay and bisexual men who inject drugs in San Francisco, 1988 to 2000. J Acquir Immune Defic Syndr. 2001 Nov 01; 28(3):264-9. PMID: 11694834.
      View in: PubMed
    62. Edlin BR, Seal K, Lorvick J, Kral AH, Ciccarone DH, Moore LD, Lo B. Is it justifiable to withhold treatment for hepatitis C from illicit-drug users? N Engl J Med. 2001 Jul 19; 345(3):211-5. PMID: 11463019; PMCID: PMC1510901.
    63. Ochoa KC, Hahn JA, Seal K, Moss AR. Overdosing among young injection drug users in San Francisco. Addict Behav. 2001 May-Jun; 26(3):453-60. PMID: 11436937.
      View in: PubMed
    64. Lorvick J, Kral AH, Seal K, Gee L, Edlin BR. Prevalence and duration of hepatitis C among injection drug users in San Francisco, Calif. Am J Public Health. 2001 Jan; 91(1):46-7. PMID: 11189823; PMCID: PMC1446502.
    65. Seal K, Ochoa KC, Hahn JA, Tulsky JP, Edlin BR, Moss AR. Risk of hepatitis B infection among young injection drug users in San Francisco: opportunities for intervention. West J Med. 2000 Jan; 172(1):16-20. PMID: 10695436; PMCID: PMC1070710.
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