Shauna Farr-Jones, PhD

Title(s)Academic Coordinator, Anesthesia
SchoolSchool of Medicine
Address1001 Potrero Avenue, #3C1
San Francisco CA 94110
ORCID ORCID Icon0000-0003-4130-6332 Additional info
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    Collapse Biography 
    Collapse Education and Training
    Tufts University, Boston, MAPh.D.06/1989Biochemistry
    University of Southampton, Southampton, UKBSc(Hons)6/1980Chemistry

    Collapse Overview 
    Collapse Mentoring

    Collapse Research 
    Collapse Research Activities and Funding
    Antibody Technology Reseach Center
    NIH/NCI P41CA196276Sep 24, 2014 - Aug 31, 2019
    Role: Co-Investigator
    Description: Project Manager
    Trispecific monoclonal antibody for botulinum neurotoxin intoxication therapy
    NIH R33AI101539Jun 20, 2012 - May 31, 2018
    Role: Co-Investigator
    Trispecific monoclonal antibody for botulinum neurotoxin intoxication therapy
    NIH R21AI101539Jun 1, 2012 - May 31, 2014
    Role: Co-Investigator
    NIH 272201100031C-4-0-1Sep 30, 2011 - Sep 30, 2016
    Role: Co-Investigator
    NIH 272201100031C-1-0-1Sep 27, 2011 - Aug 1, 2015
    Role: Co-Investigator
    NIH 272201100031C-0-0-1Sep 27, 2011 - Sep 29, 2014
    Role: Co-Investigator
    Resource for Biocomputing, Visualization, and Informatics
    NIH/NCRR P41RR001081Jun 1, 1976 - Sep 14, 2012
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Featured Publications

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. A Three-Monoclonal Antibody Combination Potently Neutralizes BoNT/G Toxin in Mice. Toxins (Basel). 2023 04 30; 15(5). Fan Y, Lou J, Tam CC, Wen W, Conrad F, Leal da Silva Alves P, Cheng LW, Garcia-Rodriguez C, Farr-Jones S, Marks JD. PMID: 37235351; PMCID: PMC10222606.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    2. Multicolor fluorescence activated cell sorting to generate humanized monoclonal antibody binding seven subtypes of BoNT/F. PLoS One. 2022; 17(9):e0273512. Fan Y, Sun Z, Conrad F, Wen W, Zhao L, Lou J, Zhou Y, Farr-Jones S, Marks JD. PMID: 36048906; PMCID: PMC9436041.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    3. Neutralizing Concentrations of Anti-Botulinum Toxin Antibodies Positively Correlate with Mouse Neutralization Assay Results in a Guinea Pig Model. Toxins (Basel). 2021 09 21; 13(9). Tomic MT, Farr-Jones S, Syar ES, Niemuth N, Kobs D, Hackett MJ, Espinoza Y, Martinez Z, Pham K, Snow DM, Marks JD, Cobb RR. PMID: 34564675; PMCID: PMC8471557.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    4. A Four-Monoclonal Antibody Combination Potently Neutralizes Multiple Botulinum Neurotoxin Serotypes C and D. Toxins (Basel). 2021 09 10; 13(9). Garcia-Rodriguez C, Yan S, Geren IN, Knopp KA, Dong J, Sun Z, Lou J, Conrad F, Wen WH, Farr-Jones S, Smith TJ, Brown JL, Skerry JC, Smith LA, Marks JD. PMID: 34564645; PMCID: PMC8472335.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    5. Identification of recombinant Fabs for structural and functional characterization of HIV-host factor complexes. PLoS One. 2021; 16(5):e0250318. Sevillano N, Green EM, Votteler J, Kim DY, Ren X, Yang B, Liu X, Lourenço AL, Hurley JH, Farr-Jones S, Gross JD, Cheng Y, Craik CS. PMID: 33983947; PMCID: PMC8118348.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    6. A Monoclonal Antibody Combination against both Serotypes A and B Botulinum Toxin Prevents Inhalational Botulism in a Guinea Pig Model. Toxins (Basel). 2021 01 05; 13(1). Snow DM, Cobb RR, Martinez J, Finger-Baker I, Collins L, Terpening S, Syar ES, Niemuth N, Kobs D, Barnewall R, Farr-Jones S, Marks JD, Tomic MT. PMID: 33466411; PMCID: PMC7824882.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    7. Antibody-Drug Conjugates Targeting the Urokinase Receptor (uPAR) as a Possible Treatment of Aggressive Breast Cancer. Antibodies (Basel). 2019 Nov 05; 8(4). Harel ET, Drake PM, Barfield RM, Lui I, Farr-Jones S, Van't Veer L, Gartner ZJ, Green EM, Lourenço AL, Cheng Y, Hann BC, Rabuka D, Craik CS. PMID: 31694242; PMCID: PMC6963874.
      View in: PubMed   Mentions: 10  
    8. Pharmacokinetics of Human Recombinant Anti-Botulinum Toxin Antibodies in Rats. Toxins (Basel). 2019 06 17; 11(6). Espinoza Y, Wong D, Ahene A, Der K, Martinez Z, Pham J, Cobb RR, Farr-Jones S, Marks JD, Tomic MT. PMID: 31212950; PMCID: PMC6628388.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    9. Monoclonal Antibody Combinations Prevent Serotype A and Serotype B Inhalational Botulism in a Guinea Pig Model. Toxins (Basel). 2019 04 06; 11(4). Tomic MT, Espinoza Y, Martinez Z, Pham K, Cobb RR, Snow DM, Earnhart CG, Pals T, Syar ES, Niemuth N, Kobs DJ, Farr-Jones S, Marks JD. PMID: 30959899; PMCID: PMC6520708.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    10. An ambient temperature-stable antitoxin of nine co-formulated antibodies for botulism caused by serotypes A, B and E. PLoS One. 2018; 13(5):e0197011. Li M, Lee D, Obi CR, Freeberg JK, Farr-Jones S, Tomic MT. PMID: 29746518; PMCID: PMC5944936.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    11. Antibody engineering to improve manufacturability. Protein Expr Purif. 2018 09; 149:75-83. Wijesuriya SD, Pongo E, Tomic M, Zhang F, Garcia-Rodriquez C, Conrad F, Farr-Jones S, Marks JD, Horwitz AH. PMID: 29655788.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    12. A Three Monoclonal Antibody Combination Potently Neutralizes Multiple Botulinum Neurotoxin Serotype E Subtypes. Toxins (Basel). 2018 03 01; 10(3). Garcia-Rodriguez C, Razai A, Geren IN, Lou J, Conrad F, Wen WH, Farr-Jones S, Smith TJ, Brown JL, Skerry JC, Smith LA, Marks JD. PMID: 29494481; PMCID: PMC5869393.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    13. A Single Tri-Epitopic Antibody Virtually Recapitulates the Potency of a Combination of Three Monoclonal Antibodies in Neutralization of Botulinum Neurotoxin Serotype A. Toxins (Basel). 2018 02 15; 10(2). Lou J, Wen W, Conrad F, Meng Q, Dong J, Sun Z, Garcia-Rodriguez C, Farr-Jones S, Cheng LW, Henderson TD, Brown JL, Smith TJ, Smith LA, Cormier A, Marks JD. PMID: 29462889; PMCID: PMC5848185.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    14. Discovery of internalizing antibodies to basal breast cancer cells. Protein Eng Des Sel. 2018 01 01; 31(1):17-28. Zhou Y, Zou H, Yau C, Zhao L, Hall SC, Drummond DC, Farr-Jones S, Park JW, Benz CC, Marks JD. PMID: 29301020; PMCID: PMC6283401.
      View in: PubMed   Mentions: 2     Fields:    
    15. High-throughput screening: update on practices and success. J Biomol Screen. 2006 Oct; 11(7):864-9. Fox S, Farr-Jones S, Sopchak L, Boggs A, Nicely HW, Khoury R, Biros M. PMID: 16973922.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    16. High-throughput screening: searching for higher productivity. J Biomol Screen. 2004 Jun; 9(4):354-8. Fox S, Farr-Jones S, Sopchak L, Boggs A, Comley J. PMID: 15191652.
      View in: PubMed   Mentions: 8     Fields:    
    17. High throughput screening 2002: moving toward increased success rates. J Biomol Screen. 2002 Aug; 7(4):313-6. Fox S, Wang H, Sopchak L, Farr-Jones S. PMID: 12230884.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    18. Business and science of proteomics--third annual event. Next-generation technologies for high-throughput proteomics. IDrugs. 2001 Nov; 4(11):1235-6. Farr-Jones S. PMID: 15942822.
      View in: PubMed   Mentions:    Fields:    
    19. The Internet for nuclear magnetic resonance spectroscopists. Methods Enzymol. 2001; 338:247-57. Avizonis D, Farr-Jones S. PMID: 11460551.
      View in: PubMed   Mentions:    Fields:    
    20. Chemokine antagonists as anti-inflammatory and antiviral agents II. IDrugs. 2000 Jun; 3(6):584-5. Farr-Jones S. PMID: 16096911.
      View in: PubMed   Mentions:    Fields:    
    21. Solution structure of Syrian hamster prion protein rPrP(90-231). Biochemistry. 1999 Apr 27; 38(17):5362-77. Liu H, Farr-Jones S, Ulyanov NB, Llinas M, Marqusee S, Groth D, Cohen FE, Prusiner SB, James TL. PMID: 10220323.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCells
    22. High Throughput Screening for Drug Discovery: Continually Transitioning into New Technology. J Biomol Screen. 1999; 4(4):183-186. Fox S, Farr-Jones S, Yund MA. PMID: 10838437.
      View in: PubMed   Mentions: 10     Fields:    
    23. NMR determination of the major solution conformation of a peptoid pentamer with chiral side chains. Proc Natl Acad Sci U S A. 1998 Apr 14; 95(8):4309-14. Armand P, Kirshenbaum K, Goldsmith RA, Farr-Jones S, Barron AE, Truong KT, Dill KA, Mierke DF, Cohen FE, Zuckermann RN, Bradley EK. PMID: 9539733; PMCID: PMC22485.
      View in: PubMed   Mentions: 47     Fields:    Translation:Cells
    24. Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform. Proc Natl Acad Sci U S A. 1997 Sep 16; 94(19):10086-91. James TL, Liu H, Ulyanov NB, Farr-Jones S, Zhang H, Donne DG, Kaneko K, Groth D, Mehlhorn I, Prusiner SB, Cohen FE. PMID: 9294167; PMCID: PMC23313.
      View in: PubMed   Mentions: 132     Fields:    Translation:HumansAnimalsCells
    25. Solution structure of omega-conotoxin MVIIC, a high affinity ligand of P-type calcium channels, using 1H NMR spectroscopy and complete relaxation matrix analysis. J Mol Biol. 1995 Apr 21; 248(1):106-24. Farr-Jones S, Miljanich GP, Nadasdi L, Ramachandran J, Basus VJ. PMID: 7731037.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    26. Converting trypsin to chymotrypsin: ground-state binding does not determine substrate specificity. Biochemistry. 1994 Jul 26; 33(29):8764-9. Hedstrom L, Farr-Jones S, Kettner CA, Rutter WJ. PMID: 8038166.
      View in: PubMed   Mentions: 14     Fields:    Translation:Cells
    27. Crystal versus solution structure of enzymes: NMR spectroscopy of a peptide boronic acid-serine protease complex in the crystalline state. Proc Natl Acad Sci U S A. 1989 Sep; 86(18):6922-4. Farr-Jones S, Smith SO, Kettner CA, Griffin RG, Bachovchin WW. PMID: 2780549; PMCID: PMC297962.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    28. Crystal versus solution structures of enzymes: NMR spectroscopy of a crystalline serine protease. Science. 1989 May 26; 244(4907):961-4. Smith SO, Farr-Jones S, Griffin RG, Bachovchin WW. PMID: 2499045.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    29. Nitrogen-15 NMR spectroscopy of the catalytic-triad histidine of a serine protease in peptide boronic acid inhibitor complexes. Biochemistry. 1988 Oct 04; 27(20):7689-97. Bachovchin WW, Wong WY, Farr-Jones S, Shenvi AB, Kettner CA. PMID: 3207700.
      View in: PubMed   Mentions: 19     Fields:    Translation:Cells
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