Shauna Farr-Jones • UCSF Profiles

Shauna Farr-Jones, PhD

Title(s)	Academic Coordinator, Anesthesia
School	School of Medicine
Address	2540 23rd Street, #3C1 San Francisco CA 94110
Phone	415-754-8091
ORCID	0000-0003-4130-6332
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Biography

Education and Training

Tufts University, Boston, MA	Ph.D.	06/1989	Biochemistry
University of Southampton, Southampton, UK	BSc(Hons)	6/1980	Chemistry

Research

Research Activities and Funding

Antibody Technology Reseach Center
NIH/NCI P41CA196276Sep 24, 2014 - Aug 31, 2019
Role: Co-Investigator
Description: Project Manager

Trispecific monoclonal antibody for botulinum neurotoxin intoxication therapy
NIH R33AI101539Jun 20, 2012 - May 31, 2018
Role: Co-Investigator

Trispecific monoclonal antibody for botulinum neurotoxin intoxication therapy
NIH R21AI101539Jun 1, 2012 - May 31, 2014
Role: Co-Investigator

BROAD SPECTRUM MONOCLONAL ANTIBODY-BASED THERAPEUTIC FOR BOTULISM
NIH 272201100031C-4-0-1Sep 30, 2011 - Sep 30, 2016
Role: Co-Investigator

BROAD SPECTRUM MONOCLONAL ANTIBODY-BASED THERAPEUTIC FOR BOTULISM
NIH 272201100031C-1-0-1Sep 27, 2011 - Aug 1, 2015
Role: Co-Investigator

BROAD SPECTRUM MONOCLONAL ANTIBODY-BASED THERAPEUTIC FOR BOTULISM
NIH 272201100031C-0-0-1Sep 27, 2011 - Sep 29, 2014
Role: Co-Investigator

Resource for Biocomputing, Visualization, and Informatics
NIH/NCRR P41RR001081Jun 1, 1976 - Sep 14, 2012
Role: Co-Investigator

ORNG Applications

Featured Publications

Faculty Mentoring

Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

A Three-Monoclonal Antibody Combination Potently Neutralizes BoNT/G Toxin in Mice. Toxins (Basel). 2023 04 30; 15(5). Fan Y, Lou J, Tam CC, Wen W, Conrad F, Leal da Silva Alves P, Cheng LW, Garcia-Rodriguez C, Farr-Jones S, Marks JD. PMID: 37235351; PMCID: PMC10222606.

View in: PubMed Mentions: Fields:
Tox Toxicology
Translation:Animals
Multicolor fluorescence activated cell sorting to generate humanized monoclonal antibody binding seven subtypes of BoNT/F. PLoS One. 2022; 17(9):e0273512. Fan Y, Sun Z, Conrad F, Wen W, Zhao L, Lou J, Zhou Y, Farr-Jones S, Marks JD. PMID: 36048906; PMCID: PMC9436041.

View in: PubMed Mentions: 2 Fields:
Med Medicine (General)Sci Science
Translation:Humans Animals Cells
Neutralizing Concentrations of Anti-Botulinum Toxin Antibodies Positively Correlate with Mouse Neutralization Assay Results in a Guinea Pig Model. Toxins (Basel). 2021 09 21; 13(9). Tomic MT, Farr-Jones S, Syar ES, Niemuth N, Kobs D, Hackett MJ, Espinoza Y, Martinez Z, Pham K, Snow DM, Marks JD, Cobb RR. PMID: 34564675; PMCID: PMC8471557.

View in: PubMed Mentions: 3 Fields:
Tox Toxicology
Translation:Animals Cells
A Four-Monoclonal Antibody Combination Potently Neutralizes Multiple Botulinum Neurotoxin Serotypes C and D. Toxins (Basel). 2021 09 10; 13(9). Garcia-Rodriguez C, Yan S, Geren IN, Knopp KA, Dong J, Sun Z, Lou J, Conrad F, Wen WH, Farr-Jones S, Smith TJ, Brown JL, Skerry JC, Smith LA, Marks JD. PMID: 34564645; PMCID: PMC8472335.

View in: PubMed Mentions: 5 Fields:
Tox Toxicology
Translation:Humans Animals
Identification of recombinant Fabs for structural and functional characterization of HIV-host factor complexes. PLoS One. 2021; 16(5):e0250318. Sevillano N, Green EM, Votteler J, Kim DY, Ren X, Yang B, Liu X, Lourenço AL, Hurley JH, Farr-Jones S, Gross JD, Cheng Y, Craik CS. PMID: 33983947; PMCID: PMC8118348.

View in: PubMed Mentions: Fields:
Med Medicine (General)Sci Science
Translation:Humans Cells
A Monoclonal Antibody Combination against both Serotypes A and B Botulinum Toxin Prevents Inhalational Botulism in a Guinea Pig Model. Toxins (Basel). 2021 01 05; 13(1). Snow DM, Cobb RR, Martinez J, Finger-Baker I, Collins L, Terpening S, Syar ES, Niemuth N, Kobs D, Barnewall R, Farr-Jones S, Marks JD, Tomic MT. PMID: 33466411; PMCID: PMC7824882.

View in: PubMed Mentions: 1 Fields:
Tox Toxicology
Translation:Humans Animals
Antibody-Drug Conjugates Targeting the Urokinase Receptor (uPAR) as a Possible Treatment of Aggressive Breast Cancer. Antibodies (Basel). 2019 Nov 05; 8(4). Harel ET, Drake PM, Barfield RM, Lui I, Farr-Jones S, Van't Veer L, Gartner ZJ, Green EM, Lourenço AL, Cheng Y, Hann BC, Rabuka D, Craik CS. PMID: 31694242; PMCID: PMC6963874.

View in: PubMed Mentions: 10
Pharmacokinetics of Human Recombinant Anti-Botulinum Toxin Antibodies in Rats. Toxins (Basel). 2019 06 17; 11(6). Espinoza Y, Wong D, Ahene A, Der K, Martinez Z, Pham J, Cobb RR, Farr-Jones S, Marks JD, Tomic MT. PMID: 31212950; PMCID: PMC6628388.

View in: PubMed Mentions: 6 Fields:
Tox Toxicology
Translation:Humans Animals
Monoclonal Antibody Combinations Prevent Serotype A and Serotype B Inhalational Botulism in a Guinea Pig Model. Toxins (Basel). 2019 04 06; 11(4). Tomic MT, Espinoza Y, Martinez Z, Pham K, Cobb RR, Snow DM, Earnhart CG, Pals T, Syar ES, Niemuth N, Kobs DJ, Farr-Jones S, Marks JD. PMID: 30959899; PMCID: PMC6520708.

View in: PubMed Mentions: 14 Fields:
Tox Toxicology
Translation:Animals
An ambient temperature-stable antitoxin of nine co-formulated antibodies for botulism caused by serotypes A, B and E. PLoS One. 2018; 13(5):e0197011. Li M, Lee D, Obi CR, Freeberg JK, Farr-Jones S, Tomic MT. PMID: 29746518; PMCID: PMC5944936.

View in: PubMed Mentions: 6 Fields:
Med Medicine (General)Sci Science
Translation:Humans
Antibody engineering to improve manufacturability. Protein Expr Purif. 2018 09; 149:75-83. Wijesuriya SD, Pongo E, Tomic M, Zhang F, Garcia-Rodriquez C, Conrad F, Farr-Jones S, Marks JD, Horwitz AH. PMID: 29655788.

View in: PubMed Mentions: 3 Fields:
Mol Molecular Biology
Translation:Humans Animals Cells
A Three Monoclonal Antibody Combination Potently Neutralizes Multiple Botulinum Neurotoxin Serotype E Subtypes. Toxins (Basel). 2018 03 01; 10(3). Garcia-Rodriguez C, Razai A, Geren IN, Lou J, Conrad F, Wen WH, Farr-Jones S, Smith TJ, Brown JL, Skerry JC, Smith LA, Marks JD. PMID: 29494481; PMCID: PMC5869393.

View in: PubMed Mentions: 24 Fields:
Tox Toxicology
Translation:Humans
A Single Tri-Epitopic Antibody Virtually Recapitulates the Potency of a Combination of Three Monoclonal Antibodies in Neutralization of Botulinum Neurotoxin Serotype A. Toxins (Basel). 2018 02 15; 10(2). Lou J, Wen W, Conrad F, Meng Q, Dong J, Sun Z, Garcia-Rodriguez C, Farr-Jones S, Cheng LW, Henderson TD, Brown JL, Smith TJ, Smith LA, Cormier A, Marks JD. PMID: 29462889; PMCID: PMC5848185.

View in: PubMed Mentions: 5 Fields:
Tox Toxicology
Translation:Animals Cells
Discovery of internalizing antibodies to basal breast cancer cells. Protein Eng Des Sel. 2018 01 01; 31(1):17-28. Zhou Y, Zou H, Yau C, Zhao L, Hall SC, Drummond DC, Farr-Jones S, Park JW, Benz CC, Marks JD. PMID: 29301020; PMCID: PMC6283401.

View in: PubMed Mentions: 2 Fields:
Bio Biochemistry Bio Biotechnology
Translation:Humans Cells
High-throughput screening: update on practices and success. J Biomol Screen. 2006 Oct; 11(7):864-9. Fox S, Farr-Jones S, Sopchak L, Boggs A, Nicely HW, Khoury R, Biros M. PMID: 16973922.

View in: PubMed Mentions: 40 Fields:
Mol Molecular Biology
Translation:Humans Cells
High-throughput screening: searching for higher productivity. J Biomol Screen. 2004 Jun; 9(4):354-8. Fox S, Farr-Jones S, Sopchak L, Boggs A, Comley J. PMID: 15191652.

View in: PubMed Mentions: 8 Fields:
Mol Molecular Biology
High throughput screening 2002: moving toward increased success rates. J Biomol Screen. 2002 Aug; 7(4):313-6. Fox S, Wang H, Sopchak L, Farr-Jones S. PMID: 12230884.

View in: PubMed Mentions: 1 Fields:
Mol Molecular Biology
Translation:Humans
Business and science of proteomics--third annual event. Next-generation technologies for high-throughput proteomics. IDrugs. 2001 Nov; 4(11):1235-6. Farr-Jones S. PMID: 15942822.

View in: PubMed Mentions: Fields:
Pha Pharmacology
The Internet for nuclear magnetic resonance spectroscopists. Methods Enzymol. 2001; 338:247-57. Avizonis D, Farr-Jones S. PMID: 11460551.

View in: PubMed Mentions: Fields:
Bio Biochemistry
Chemokine antagonists as anti-inflammatory and antiviral agents II. IDrugs. 2000 Jun; 3(6):584-5. Farr-Jones S. PMID: 16096911.

View in: PubMed Mentions: Fields:
Pha Pharmacology
Solution structure of Syrian hamster prion protein rPrP(90-231). Biochemistry. 1999 Apr 27; 38(17):5362-77. Liu H, Farr-Jones S, Ulyanov NB, Llinas M, Marqusee S, Groth D, Cohen FE, Prusiner SB, James TL. PMID: 10220323.

View in: PubMed Mentions: 58 Fields:
Bio Biochemistry
Translation:Animals Cells
High Throughput Screening for Drug Discovery: Continually Transitioning into New Technology. J Biomol Screen. 1999; 4(4):183-186. Fox S, Farr-Jones S, Yund MA. PMID: 10838437.

View in: PubMed Mentions: 9 Fields:
Mol Molecular Biology
NMR determination of the major solution conformation of a peptoid pentamer with chiral side chains. Proc Natl Acad Sci U S A. 1998 Apr 14; 95(8):4309-14. Armand P, Kirshenbaum K, Goldsmith RA, Farr-Jones S, Barron AE, Truong KT, Dill KA, Mierke DF, Cohen FE, Zuckermann RN, Bradley EK. PMID: 9539733; PMCID: PMC22485.

View in: PubMed Mentions: 47 Fields:
Sci Science
Translation:Cells
Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform. Proc Natl Acad Sci U S A. 1997 Sep 16; 94(19):10086-91. James TL, Liu H, Ulyanov NB, Farr-Jones S, Zhang H, Donne DG, Kaneko K, Groth D, Mehlhorn I, Prusiner SB, Cohen FE. PMID: 9294167; PMCID: PMC23313.

View in: PubMed Mentions: 132 Fields:
Sci Science
Translation:Humans Animals Cells
Solution structure of omega-conotoxin MVIIC, a high affinity ligand of P-type calcium channels, using 1H NMR spectroscopy and complete relaxation matrix analysis. J Mol Biol. 1995 Apr 21; 248(1):106-24. Farr-Jones S, Miljanich GP, Nadasdi L, Ramachandran J, Basus VJ. PMID: 7731037.

View in: PubMed Mentions: 6 Fields:
Mol Molecular Biology
Translation:Animals Cells
Converting trypsin to chymotrypsin: ground-state binding does not determine substrate specificity. Biochemistry. 1994 Jul 26; 33(29):8764-9. Hedstrom L, Farr-Jones S, Kettner CA, Rutter WJ. PMID: 8038166.

View in: PubMed Mentions: 13 Fields:
Bio Biochemistry
Translation:Cells
Crystal versus solution structure of enzymes: NMR spectroscopy of a peptide boronic acid-serine protease complex in the crystalline state. Proc Natl Acad Sci U S A. 1989 Sep; 86(18):6922-4. Farr-Jones S, Smith SO, Kettner CA, Griffin RG, Bachovchin WW. PMID: 2780549; PMCID: PMC297962.

View in: PubMed Mentions: 7 Fields:
Sci Science
Translation:Cells
Crystal versus solution structures of enzymes: NMR spectroscopy of a crystalline serine protease. Science. 1989 May 26; 244(4907):961-4. Smith SO, Farr-Jones S, Griffin RG, Bachovchin WW. PMID: 2499045.

View in: PubMed Mentions: 11 Fields:
Sci Science
Translation:Cells
Nitrogen-15 NMR spectroscopy of the catalytic-triad histidine of a serine protease in peptide boronic acid inhibitor complexes. Biochemistry. 1988 Oct 04; 27(20):7689-97. Bachovchin WW, Wong WY, Farr-Jones S, Shenvi AB, Kettner CA. PMID: 3207700.

View in: PubMed Mentions: 19 Fields:
Bio Biochemistry
Translation:Cells