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Proteomics identifies potential immunological drivers of postinfection brain atrophy and cognitive decline. Nat Aging. 2024 Aug 14.
Duggan MR, Peng Z, Sipilä PN, Lindbohm JV, Chen J, Lu Y, Davatzikos C, Erus G, Hohman TJ, Andrews SJ, Candia J, Tanaka T, Joynes CM, Alvarado CX, Nalls MA, Cordon J, Daya GN, An Y, Lewis A, Moghekar A, Palta P, Coresh J, Ferrucci L, Kivimäki M, Walker KA. PMID: 39143319.
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PubMed Mentions:
1 Fields:
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Disentangling the causal effects of education and participation bias on Alzheimer's disease using Mendelian Randomization. medRxiv. 2024 Jul 10.
Chatterjee A, Cavaillès C, Davies NM, Yaffe K, Andrews SJ. PMID: 39040183; PMCID: PMC11261951.
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PubMed Mentions:
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Visual Impairment, Eye Conditions, and Diagnoses of Neurodegeneration and Dementia. JAMA Netw Open. 2024 Jul 01; 7(7):e2424539.
Ferguson EL, Thoma M, Buto PT, Wang J, Glymour MM, Hoffmann TJ, Choquet H, Andrews SJ, Yaffe K, Casaletto K, Brenowitz WD. PMID: 39078629; PMCID: PMC11289698.
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PubMed Mentions: Fields:
Translation:
Humans
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Snoring and risk of dementia: a prospective cohort and Mendelian randomization study. Sleep. 2024 Jun 29.
Gao Y, Andrews S, Daghlas I, Brenowitz WD, Raji CA, Yaffe K, Leng Y. PMID: 38943476.
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PubMed Mentions: Fields:
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The Role of Genomic-Informed Risk Assessments in Predicting Dementia Outcomes. medRxiv. 2024 Apr 30.
Andrews SJ, Jonson C, Fulton-Howard B, Renton AE, Yokoyama JS, Yaffe K, Alzheimer’s Disease Neuroimaging Initiative. PMID: 38903124; PMCID: PMC11188112.
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PubMed Mentions:
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Modifiable risk factors, APOE and risk of Alzheimer disease: one size does not fit all. medRxiv. 2024 Apr 29.
Andrews SJ, Belloy ME, Renton AE, Fulton-Howard B, Brenowitz WD, Yaffe K, Alzheimer’s Disease Neuroimaging Initiative. PMID: 38746455; PMCID: PMC11092714.
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PubMed Mentions:
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Developing Topics. Alzheimers Dement. 2023 Dec; 19 Suppl 24:e082772.
Belloy ME, Andrews SJ, Guen YL, Napolioni V, Greicius MD. PMID: 39120754.
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PubMed Mentions:
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APOE Genotype and Alzheimer Disease Risk Across Age, Sex, and Population Ancestry. JAMA Neurol. 2023 Dec 01; 80(12):1284-1294.
Belloy ME, Andrews SJ, Le Guen Y, Cuccaro M, Farrer LA, Napolioni V, Greicius MD. PMID: 37930705; PMCID: PMC10628838.
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PubMed Mentions:
13 Fields:
Translation:
Humans
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Causal Associations of Sleep Apnea with Alzheimer's Disease and Cardiovascular Disease: a Bidirectional Mendelian Randomization Analysis. medRxiv. 2023 Nov 22.
Cavaillès C, Andrews SJ, Leng Y, Chatterjee A, Daghlas I, Yaffe K. PMID: 38045267; PMCID: PMC10690337.
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PubMed Mentions:
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Snoring and risk of dementia: a prospective cohort and Mendelian randomization study. medRxiv. 2023 Oct 13.
Gao Y, Andrews S, Brenowitz W, Raji CA, Yaffe K, Leng Y. PMID: 37873444; PMCID: PMC10593011.
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PubMed Mentions:
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Blood-Based Transcriptomic Biomarkers Are Predictive of Neurodegeneration Rather Than Alzheimer's Disease. Int J Mol Sci. 2023 Oct 09; 24(19).
Shvetcov A, Thomson S, Spathos J, Cho AN, Wilkins HM, Andrews SJ, Delerue F, Couttas TA, Issar JK, Isik F, Kaur S, Drummond E, Dobson-Stone C, Duffy SL, Rogers NM, Catchpoole D, Gold WA, Swerdlow RH, Brown DA, Finney CA. PMID: 37834458; PMCID: PMC10573468.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Shared genetic risk loci between Alzheimer's disease and related dementias, Parkinson's disease, and amyotrophic lateral sclerosis. Alzheimers Res Ther. 2023 06 16; 15(1):113.
Wainberg M, Andrews SJ, Tripathy SJ. PMID: 37328865; PMCID: PMC10273745.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Genetic associations with age at dementia onset in the PSEN1 E280A Colombian kindred. Alzheimers Dement. 2023 09; 19(9):3835-3847.
Cochran JN, Acosta-Uribe J, Esposito BT, Madrigal L, Aguillón D, Giraldo MM, Taylor JW, Bradley J, Fulton-Howard B, Andrews SJ, Acosta-Baena N, Alzate D, Garcia GP, Piedrahita F, Lopez HE, Anderson AG, Rodriguez-Nunez I, Roberts K, Absher D, Myers RM, Beecham GW, Reitz C, Rizzardi LF, Fernandez MV, Goate AM, Cruchaga C, Renton AE, Lopera F, Kosik KS. PMID: 36951251; PMCID: PMC10514237.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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The complex genetic architecture of Alzheimer's disease: novel insights and future directions. EBioMedicine. 2023 Apr; 90:104511.
Andrews SJ, Renton AE, Fulton-Howard B, Podlesny-Drabiniok A, Marcora E, Goate AM. PMID: 36907103; PMCID: PMC10024184.
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PubMed Mentions:
47 Fields:
Translation:
Humans
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Microglial efferocytosis: Diving into the Alzheimer's disease gene pool. Neuron. 2022 11 02; 110(21):3513-3533.
Romero-Molina C, Garretti F, Andrews SJ, Marcora E, Goate AM. PMID: 36327897.
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PubMed Mentions:
19 Fields:
Translation:
HumansCells
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The role of mitochondrial genome abundance in Alzheimer's disease. Alzheimers Dement. 2023 05; 19(5):2069-2083.
Harerimana NV, Paliwali D, Romero-Molina C, Bennett DA, Pa J, Goate A, Swerdlow RH, Andrews SJ. PMID: 36224040.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Sex differences in the genetic architecture of cognitive resilience to Alzheimer's disease. Brain. 2022 07 29; 145(7):2541-2554.
Eissman JM, Dumitrescu L, Mahoney ER, Smith AN, Mukherjee S, Lee ML, Scollard P, Choi SE, Bush WS, Engelman CD, Lu Q, Fardo DW, Trittschuh EH, Mez J, Kaczorowski CC, Hernandez Saucedo H, Widaman KF, Buckley RF, Properzi MJ, Mormino EC, Yang HS, Harrison TM, Hedden T, Nho K, Andrews SJ, Tommet D, Hadad N, Sanders RE, Ruderfer DM, Gifford KA, Zhong X, Raghavan NS, Vardarajan BN, Alzheimer’s Disease Neuroimaging Initiative (ADNI), Alzheimer’s Disease Genetics Consortium (ADGC), A4 Study Team, Pericak-Vance MA, Farrer LA, Wang LS, Cruchaga C, Schellenberg GD, Cox NJ, Haines JL, Keene CD, Saykin AJ, Larson EB, Sperling RA, Mayeux R, Cuccaro ML, Bennett DA, Schneider JA, Crane PK, Jefferson AL, Hohman TJ. PMID: 35552371; PMCID: PMC9337804.
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PubMed Mentions:
23 Fields:
Translation:
Humans
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A Mitochondrial DNA Haplogroup Defines Patterns of Five-Year Cognitive Change. J Alzheimers Dis. 2022; 89(3):913-922.
Watts A, Chalise P, Hu J, Hui D, Pa J, Andrews SJ, Michaelis EK, Swerdlow RH. PMID: 35964186; PMCID: PMC10015634.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Integrative metabolomics-genomics approach reveals key metabolic pathways and regulators of Alzheimer's disease. Alzheimers Dement. 2022 06; 18(6):1260-1278.
Horgusluoglu E, Neff R, Song WM, Wang M, Wang Q, Arnold M, Krumsiek J, Galindo-Prieto B, Ming C, Nho K, Kastenmüller G, Han X, Baillie R, Zeng Q, Andrews S, Cheng H, Hao K, Goate A, Bennett DA, Saykin AJ, Kaddurah-Daouk R, Zhang B, Alzheimer's Disease Neuroimaging Initiative (ADNI), Alzheimer Disease Metabolomics Consortium. PMID: 34757660; PMCID: PMC9085975.
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PubMed Mentions:
34 Fields:
Translation:
Humans
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Genome-wide association study and functional validation implicates JADE1 in tauopathy. Acta Neuropathol. 2022 01; 143(1):33-53.
Farrell K, Kim S, Han N, Iida MA, Gonzalez EM, Otero-Garcia M, Walker JM, Richardson TE, Renton AE, Andrews SJ, Fulton-Howard B, Humphrey J, Vialle RA, Bowles KR, de Paiva Lopes K, Whitney K, Dangoor DK, Walsh H, Marcora E, Hefti MM, Casella A, Sissoko CT, Kapoor M, Novikova G, Udine E, Wong G, Tang W, Bhangale T, Hunkapiller J, Ayalon G, Graham RR, Cherry JD, Cortes EP, Borukov VY, McKee AC, Stein TD, Vonsattel JP, Teich AF, Gearing M, Glass J, Troncoso JC, Frosch MP, Hyman BT, Dickson DW, Murray ME, Attems J, Flanagan ME, Mao Q, Mesulam MM, Weintraub S, Woltjer RL, Pham T, Kofler J, Schneider JA, Yu L, Purohit DP, Haroutunian V, Hof PR, Gandy S, Sano M, Beach TG, Poon W, Kawas CH, Corrada MM, Rissman RA, Metcalf J, Shuldberg S, Salehi B, Nelson PT, Trojanowski JQ, Lee EB, Wolk DA, McMillan CT, Keene CD, Latimer CS, Montine TJ, Kovacs GG, Lutz MI, Fischer P, Perrin RJ, Cairns NJ, Franklin EE, Cohen HT, Raj T, Cobos I, Frost B, Goate A, White Iii CL, Crary JF. PMID: 34719765; PMCID: PMC8786260.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimals
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A globally diverse reference alignment and panel for imputation of mitochondrial DNA variants. BMC Bioinformatics. 2021 Sep 01; 22(1):417.
McInerney TW, Fulton-Howard B, Patterson C, Paliwal D, Jermiin LS, Patel HR, Pa J, Swerdlow RH, Goate A, Easteal S, Andrews SJ, for the Alzheimer’s Disease Neuroimaging Initiative. PMID: 34470617; PMCID: PMC8409003.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Mitochondrial pathway polygenic risk scores are associated with Alzheimer's Disease. Neurobiol Aging. 2021 12; 108:213-222.
Paliwal D, McInerney TW, Pa J, Swerdlow RH, Easteal S, Andrews SJ, Alzheimer's Disease Neuroimaging Initiative. PMID: 34521561.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Mapping the human genetic architecture of COVID-19. Nature. 2021 Dec; 600(7889):472-477.
COVID-19 Host Genetics Initiative. PMID: 34237774; PMCID: PMC8674144.
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PubMed Mentions:
391 Fields:
Translation:
HumansCells
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Beyond association: successes and challenges in linking non-coding genetic variation to functional consequences that modulate Alzheimer's disease risk. Mol Neurodegener. 2021 04 21; 16(1):27.
Novikova G, Andrews SJ, Renton AE, Marcora E. PMID: 33882988; PMCID: PMC8061035.
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PubMed Mentions:
13 Fields:
Translation:
HumansCells
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Shared genetic etiology between idiopathic pulmonary fibrosis and COVID-19 severity. EBioMedicine. 2021 Mar; 65:103277.
Fadista J, Kraven LM, Karjalainen J, Andrews SJ, Geller F, COVID-19 Host Genetics Initiative, Baillie JK, Wain LV, Jenkins RG, Feenstra B. PMID: 33714028; PMCID: PMC7946355.
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PubMed Mentions:
39 Fields:
Translation:
HumansCells
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The variant call format provides efficient and robust storage of GWAS summary statistics. Genome Biol. 2021 01 13; 22(1):32.
Lyon MS, Andrews SJ, Elsworth B, Gaunt TR, Hemani G, Marcora E. PMID: 33441155; PMCID: PMC7805039.
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PubMed Mentions:
63 Fields:
Translation:
Humans
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Causal Associations Between Modifiable Risk Factors and the Alzheimer's Phenome. Ann Neurol. 2021 01; 89(1):54-65.
Andrews SJ, Fulton-Howard B, O'Reilly P, Marcora E, Goate AM, collaborators of the Alzheimer's Disease Genetics Consortium. PMID: 32996171; PMCID: PMC8088901.
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PubMed Mentions:
47 Fields:
Translation:
HumansCells
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Genetic variants and functional pathways associated with resilience to Alzheimer's disease. Brain. 2020 08 01; 143(8):2561-2575.
Dumitrescu L, Mahoney ER, Mukherjee S, Lee ML, Bush WS, Engelman CD, Lu Q, Fardo DW, Trittschuh EH, Mez J, Kaczorowski C, Hernandez Saucedo H, Widaman KF, Buckley R, Properzi M, Mormino E, Yang HS, Harrison T, Hedden T, Nho K, Andrews SJ, Tommet D, Hadad N, Sanders RE, Ruderfer DM, Gifford KA, Moore AM, Cambronero F, Zhong X, Raghavan NS, Vardarajan B, Alzheimer’s Disease Neuroimaging Initiative (ADNI), Alzheimer’s Disease Genetics Consortium (ADGC), A4 Study Team, Pericak-Vance MA, Farrer LA, Wang LS, Cruchaga C, Schellenberg G, Cox NJ, Haines JL, Keene CD, Saykin AJ, Larson EB, Sperling RA, Mayeux R, Bennett DA, Schneider JA, Crane PK, Jefferson AL, Hohman TJ. PMID: 32844198; PMCID: PMC7447518.
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PubMed Mentions:
64 Fields:
Translation:
HumansCells
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Exploratory analysis of mtDNA haplogroups in two Alzheimer's longitudinal cohorts. Alzheimers Dement. 2020 08; 16(8):1164-1172.
Swerdlow RH, Hui D, Chalise P, Sharma P, Wang X, Andrews SJ, Pa J, Mahnken JD, Morris J, Wilkins HM, Burns JM, Michaelis ML, Michaelis EK, Alzheimer's Disease Neuroimaging Initiative (ADNI). PMID: 32543785; PMCID: PMC9847473.
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PubMed Mentions:
17 Fields:
Translation:
Humans
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Role of apolipoprotein E epsilon 4 (APOE*ε4) as an independent risk factor for incident depression over a 12-year period in cognitively intact adults across the lifespan. BJPsych Open. 2020 May 08; 6(3):e47.
Burns RA, Andrews S, Cherbuin N, Anstey KJ. PMID: 32381152; PMCID: PMC7331079.
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PubMed Mentions:
5
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Interpretation of risk loci from genome-wide association studies of Alzheimer's disease. Lancet Neurol. 2020 04; 19(4):326-335.
Andrews SJ, Fulton-Howard B, Goate A. PMID: 31986256; PMCID: PMC8176461.
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PubMed Mentions:
142 Fields:
Translation:
Humans
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Association between alcohol consumption and Alzheimer's disease: A Mendelian randomization study. Alzheimers Dement. 2020 02; 16(2):345-353.
Andrews SJ, Goate A, Anstey KJ. PMID: 31786126; PMCID: PMC7057166.
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PubMed Mentions:
26 Fields:
Translation:
Humans
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Investigation of antihypertensive class, dementia, and cognitive decline: A meta-analysis. Neurology. 2020 01 21; 94(3):e267-e281.
Peters R, Yasar S, Anderson CS, Andrews S, Antikainen R, Arima H, Beckett N, Beer JC, Bertens AS, Booth A, van Boxtel M, Brayne C, Brodaty H, Carlson MC, Chalmers J, Corrada M, DeKosky S, Derby C, Dixon RA, Forette F, Ganguli M, van Gool WA, Guaita A, Hever AM, Hogan DB, Jagger C, Katz M, Kawas C, Kehoe PG, Keinanen-Kiukaanniemi S, Kenny RA, Köhler S, Kunutsor SK, Laukkanen J, Maxwell C, McFall GP, van Middelaar T, Moll van Charante EP, Ng TP, Peters J, Rawtaer I, Richard E, Rockwood K, Rydén L, Sachdev PS, Skoog I, Skoog J, Staessen JA, Stephan BCM, Sebert S, Thijs L, Trompet S, Tully PJ, Tzourio C, Vaccaro R, Vaaramo E, Walsh E, Warwick J, Anstey KJ. PMID: 31827004; PMCID: PMC7108807.
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PubMed Mentions:
39 Fields:
Translation:
Humans
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Mitonuclear interactions influence Alzheimer's disease risk. Neurobiol Aging. 2020 03; 87:138.e7-138.e14.
Andrews SJ, Fulton-Howard B, Patterson C, McFall GP, Gross A, Michaelis EK, Goate A, Swerdlow RH, Pa J, Alzheimer's Disease Neuroimaging Initiative. PMID: 31784277; PMCID: PMC7205324.
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PubMed Mentions:
13 Fields:
Translation:
Humans
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Mendelian randomization indicates that TNF is not causally associated with Alzheimer's disease. Neurobiol Aging. 2019 12; 84:241.e1-241.e3.
Andrews SJ, Goate A. PMID: 31587925.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Mitochondria and Alzheimer's: Is PTCD1 the Smoking Gun? Trends Neurosci. 2019 11; 42(11):759-762.
Pa J, Andrews SJ, Swerdlow RH. PMID: 31421943; PMCID: PMC7086432.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Alzheimer's Environmental and Genetic Risk Scores are Differentially Associated With General Cognitive Ability and Dementia Severity. Alzheimer Dis Assoc Disord. 2019 Apr-Jun; 33(2):95-103.
Andrews SJ, McFall GP, Dixon RA, Cherbuin N, Eramudugolla R, Anstey KJ. PMID: 30681434.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Protective Variants in Alzheimer's Disease. Curr Genet Med Rep. 2019 Mar; 7(1):1-12.
Andrews SJ, Fulton-Howard B, Goate A. PMID: 33117616; PMCID: PMC7591108.
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PubMed Mentions:
9
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Association of Alzheimer's Disease Genetic Risk Loci with Cognitive Performance and Decline: A Systematic Review. J Alzheimers Dis. 2019; 69(4):1109-1136.
Andrews SJ, McFall GP, Booth A, Dixon RA, Anstey KJ. PMID: 31156182.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Association of Alzheimer's genetic loci with mild behavioral impairment. Am J Med Genet B Neuropsychiatr Genet. 2018 12; 177(8):727-735.
Andrews SJ, Ismail Z, Anstey KJ, Mortby M. PMID: 30378268.
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PubMed Mentions:
27 Fields:
Translation:
Humans
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Sex Differences in the Impact of BDNF Genotype on the Longitudinal Relationship between Physical Activity and Cognitive Performance. Gerontology. 2018; 64(4):361-372.
Watts A, Andrews SJ, Anstey KJ. PMID: 29402782.
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PubMed Mentions:
18 Fields:
Translation:
Humans
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Memory Resilience to Alzheimer's Genetic Risk: Sex Effects in Predictor Profiles. J Gerontol B Psychol Sci Soc Sci. 2017 Oct 01; 72(6):937-946.
McDermott KL, McFall GP, Andrews SJ, Anstey KJ, Dixon RA. PMID: 28025282; PMCID: PMC5927155.
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PubMed Mentions:
23 Fields:
Translation:
Humans
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Validating the role of the Australian National University Alzheimer's Disease Risk Index (ANU-ADRI) and a genetic risk score in progression to cognitive impairment in a population-based cohort of older adults followed for 12 years. Alzheimers Res Ther. 2017 Mar 04; 9(1):16.
Andrews SJ, Eramudugolla R, Velez JI, Cherbuin N, Easteal S, Anstey KJ. PMID: 28259165; PMCID: PMC5336661.
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PubMed Mentions:
15 Fields:
Translation:
Humans
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Late Onset Alzheimer's Disease Risk Variants in Cognitive Decline: The PATH Through Life Study. J Alzheimers Dis. 2017; 57(2):423-436.
Andrews SJ, Das D, Anstey KJ, Easteal S. PMID: 28269768.
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PubMed Mentions:
13 Fields:
Translation:
Humans
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Association of genetic risk factors with cognitive decline: the PATH through life project. Neurobiol Aging. 2016 May; 41:150-158.
Andrews SJ, Das D, Cherbuin N, Anstey KJ, Easteal S. PMID: 27103528.
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PubMed Mentions:
25 Fields:
Translation:
Humans
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Interactive effect of APOE genotype and blood pressure on cognitive decline: the PATH through life study. J Alzheimers Dis. 2015; 44(4):1087-98.
Andrews S, Das D, Anstey KJ, Easteal S. PMID: 25672766.
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PubMed Mentions:
12 Fields:
Translation:
Humans
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Emerging evidence for functional peptides encoded by short open reading frames. Nat Rev Genet. 2014 Mar; 15(3):193-204.
Andrews SJ, Rothnagel JA. PMID: 24514441.
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PubMed Mentions:
271 Fields:
Translation:
HumansAnimalsCells