Thomas Hoffmann, PhD, MA

Title(s)Professor, Epidemiology & Biostatistics
SchoolSchool of Medicine
Address513 Parnassus Ave, MSB, #966A
San Francisco CA 94117
Phone415-476-2475
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    Collapse Biography 
    Collapse Education and Training
    University of Wisconsin MadisonBS06/2004Computer Science, Mathematics, Statistics
    Harvard UniversityAM06/2006Biostatistics
    Harvard UniversityPhD06/2009Biostatistics
    University of California San FranciscoPost-doc08/2011Biostatistics and Genetic Epidemiology

    Collapse Overview 
    Collapse Overview
    I have a broad background in statistics, genetics, and computer science, have been involved in a wide variety of theoretical and applied projects. My my applied work encompasses a wide variety of genetic association studies related to human health, including work on age-related hearing impairment, cardiovascular disease, and cancer. Driven by my applied research, my methodological work includes imputation, array design, rare variants, gene-environment interaction, and study design, and I have produced software packages that implement the methodology in these works so other researchers can freely use them.

    Collapse Research 
    Collapse Research Activities and Funding
    Sequencing not required: Imputing rare variants into a cohort of 100,000 on aging
    NIH R21AG046616Sep 30, 2013 - Apr 30, 2017
    Role: Principal Investigator
    Genome-wide Study of Hearing Impairment
    NIH K01DC013300Jul 1, 2013 - Jun 30, 2019
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. The Relationship Between Barriers to Physical Activity and Depressive Symptoms in Community-Dwelling Women. Womens Health Rep (New Rochelle). 2024; 5(1):242-249. Figueroa CA, Aguilera A, Hoffmann TJ, Fukuoka Y. PMID: 38516653; PMCID: PMC10956528.
      View in: PubMed   Mentions:
    2. Sex-specific genetic architecture of blood pressure. Nat Med. 2024 Mar 08. Yang ML, Xu C, Gupte T, Hoffmann TJ, Iribarren C, Zhou X, Ganesh SK. PMID: 38459180.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Prenatal exposure to social adversity and infant cortisol in the first year of life. Stress. 2024 Jan; 27(1):2316042. Keeton VF, Hoffmann TJ, Goodwin KM, Powell B, Tupuola S, Weiss SJ. PMID: 38377153.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Association between water insecurity and antiretroviral therapy adherence among pregnant and postpartum women in Greater Accra region of Ghana. PLOS Glob Public Health. 2024; 4(1):e0002747. Nutor JJ, Okiring J, Yeboah I, Thompson RGA, Agbadi P, Ameyaw EK, Getahun M, Agbadi W, Hoffmann TJ, Weiser SD. PMID: 38190403; PMCID: PMC10773961.
      View in: PubMed   Mentions:
    5. Genetic risk score for Alzheimer's disease predicts brain volume differences in mid and late life in UK biobank participants. Alzheimers Dement. 2024 Mar; 20(3):1978-1987. Buto PT, Wang J, La Joie R, Zimmerman SC, Glymour MM, Ackley SF, Hoffmann TJ, Yaffe K, Zeki Al Hazzouri A, Brenowitz WD. PMID: 38183377.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    6. Multi-ancestry genome-wide meta-analysis identifies novel basal cell carcinoma loci and shared genetic effects with squamous cell carcinoma. Commun Biol. 2024 01 05; 7(1):33. Choquet H, Jiang C, Yin J, Kim Y, Hoffmann TJ, 23andMe Research Team, Jorgenson E, Asgari MM. PMID: 38182794; PMCID: PMC10770328.
      View in: PubMed   Mentions: Translation:Humans
    7. Cataracts are associated with smaller gray matter brain volume among participants in the UK Biobank. Alzheimer's & Dementia. 2023 Dec 25; 19(S23). Ferguson FE, Buto BP, Thoma TM, Wang WJ, Glymour GM, Hoffmann HT, Choquet CH, Andrews AS, Yaffe YK, Casaletto CK, Brenowitz BW. .
      View in: Publisher Site   Mentions:
    8. Understanding Asian American, Native Hawaiian, and Pacific Islander participants' attitudes toward research: CARE research recruitment registry. Alzheimer's & Dementia. 2023 Dec 25; 19(S23). Park PV, Hoffmann HT, Tsoh TJ, Meyer MO, Nam NB, Tzuang TM, Kanaya KA, Hinton HL, Gallagher-Thompson GD, Vuong VQ, Kim KD, Grill GJ. .
      View in: Publisher Site   Mentions:
    9. "It has changed my life": unconditional cash transfers and personalized infant feeding support- a feasibility intervention trial among women living with HIV in western Kenya. Int Breastfeed J. 2023 Nov 27; 18(1):64. Tuthill EL, Maltby AE, Odhiambo BC, Hoffmann TJ, Nyaura M, Shikari R, Cohen CR, Weiser SD. PMID: 38012644; PMCID: PMC10680175.
      View in: PubMed   Mentions: Translation:HumansCTClinical Trials
    10. Genome-wide association study of prostate-specific antigen levels in 392,522 men identifies new loci and improves cross-ancestry prediction. medRxiv. 2023 Oct 30. Hoffmann TJ, Graff RE, Madduri RK, Rodriguez AA, Cario CL, Feng K, Jiang Y, Wang A, Klein RJ, Pierce BL, Eggener S, Tong L, Blot W, Long J, Rebbeck T, Lachance J, Andrews C, Adebiyi AO, Adusei B, Aisuodionoe-Shadrach OI, Fernandez PW, Jalloh M, Janivara R, Chen WC, Mensah JE, Agalliu I, Berndt SI, Shelley JP, Schaffer K, Machiela MJ, Freedman ND, Huang WY, Li SA, Goodman PJ, Till C, Thompson I, Lilja H, Van Den Eeden SK, Chanock SJ, Mosley JD, Conti DV, Haiman CA, Justice AC, Kachuri L, Witte JS. PMID: 37961155; PMCID: PMC10635224.
      View in: PubMed   Mentions:
    11. Low- and High-Density Lipoprotein Cholesterol and Dementia Risk Over 17 Years of Follow-up Among Members of a Large Health Care Plan. Neurology. 2023 Nov 21; 101(21):e2172-e2184. Ferguson EL, Zimmerman SC, Jiang C, Choi M, Swinnerton K, Choudhary V, Meyers TJ, Hoffmann TJ, Gilsanz P, Oni-Orisan A, Whitmer RA, Whitmer RA, Risch N, Krauss RM, Schaefer CA, Glymour MM. PMID: 37793911; PMCID: PMC10663022.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    12. European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation. Nat Commun. 2023 10 04; 14(1):6172. Budu-Aggrey A, Kilanowski A, Sobczyk MK, 23andMe Research Team, Shringarpure SS, Mitchell R, Reis K, Reigo A, Estonian Biobank Research Team, Mägi R, Nelis M, Tanaka N, Brumpton BM, Thomas LF, Sole-Navais P, Flatley C, Espuela-Ortiz A, Herrera-Luis E, Lominchar JVT, Bork-Jensen J, Marenholz I, Arnau-Soler A, Jeong A, Fawcett KA, Baurecht H, Rodriguez E, Alves AC, Kumar A, Sleiman PM, Chang X, Medina-Gomez C, Hu C, Xu CJ, Qi C, El-Heis S, Titcombe P, Antoun E, Fadista J, Wang CA, Thiering E, Wu B, Kress S, Kothalawala DM, Kadalayil L, Duan J, Zhang H, Hadebe S, Hoffmann T, Jorgenson E, Choquet H, Risch N, Njølstad P, Andreassen OA, Johansson S, Almqvist C, Gong T, Ullemar V, Karlsson R, Magnusson PKE, Szwajda A, Burchard EG, Thyssen JP, Hansen T, Kårhus LL, Dantoft TM, Jeanrenaud ACSN, Ghauri A, Arnold A, Homuth G, Lau S, Nöthen MM, Hübner N, Imboden M, Visconti A, Falchi M, Bataille V, Hysi P, Ballardini N, Boomsma DI, Hottenga JJ, Müller-Nurasyid M, Ahluwalia TS, Stokholm J, Chawes B, Schoos AM, Esplugues A, Bustamante M, Raby B, Arshad S, German C, Esko T, Milani LA, Metspalu A, Terao C, Abuabara K, Løset M, Hveem K, Jacobsson B, Pino-Yanes M, Strachan DP, Grarup N, Linneberg A, Lee YA, Probst-Hensch N, Weidinger S, Jarvelin MR, Melén E, Hakonarson H, Irvine AD, Jarvis D, Nijsten T, Duijts L, Vonk JM, Koppelmann GH, Godfrey KM, Barton SJ, Feenstra B, Pennell CE, Sly PD, Holt PG, Williams LK, Bisgaard H, Bønnelykke K, Curtin J, Simpson A, Murray C, Schikowski T, Bunyavanich S, Weiss ST, Holloway JW, Min JL, Brown SJ, Standl M, Paternoster L. PMID: 37794016; PMCID: PMC10550990.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    13. Agreement of Computerized QT and QTc Interval Measurements Between Both Bedside and Expert Nurses Using Electronic Calipers. J Cardiovasc Nurs. 2023 Oct 02. Ho K, Ganesh GK, Prasad S, Hoffmann TJ, Larsen A, Sandoval C, Berger S, Schell-Chaple H, Badilini F, Mackin LA, Pelter MM. PMID: 37787695.
      View in: PubMed   Mentions:    Fields:    
    14. Factors associated with mobile medical clinic use: a retrospective cohort study. Int J Equity Health. 2023 09 26; 22(1):195. Coaston A, Lee SJ, Johnson JK, Weiss S, Hoffmann T, Stephens C. PMID: 37749529; PMCID: PMC10521435.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. Maternal mental health after infant discharge: a quasi-experimental clinical trial of family integrated care versus family-centered care for preterm infants in U.S. NICUs. BMC Pediatr. 2023 08 10; 23(1):396. Franck LS, Gay CL, Hoffmann TJ, Kriz RM, Bisgaard R, Cormier DM, Joe P, Lothe B, Sun Y. PMID: 37563722; PMCID: PMC10413600.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    16. Association of Behavioral and Clinical Risk Factors With Cataract: A Two-Sample Mendelian Randomization Study. Invest Ophthalmol Vis Sci. 2023 07 03; 64(10):19. Jiang C, Melles RB, Sangani P, Hoffmann TJ, Hysi PG, Glymour MM, Jorgenson E, Lachke SA, Choquet H. PMID: 37459064; PMCID: PMC10362921.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    17. Influence of depression and interpersonal support on adherence to antiretroviral therapy among people living with HIV. AIDS Res Ther. 2023 06 29; 20(1):42. Nutor JJ, Gyamerah AO, Alhassan RK, Duah HO, Thompson RGA, Wilson N, Harris O, Gutierrez J, Hoffmann TJ, Getahun M, Santos GM. PMID: 37386514; PMCID: PMC10308781.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    18. Evaluating approaches for constructing polygenic risk scores for prostate cancer in men of African and European ancestry. Am J Hum Genet. 2023 07 06; 110(7):1200-1206. Darst BF, Shen J, Madduri RK, Rodriguez AA, Xiao Y, Sheng X, Saunders EJ, Dadaev T, Brook MN, Hoffmann TJ, Muir K, Wan P, Le Marchand L, Wilkens L, Wang Y, Schleutker J, MacInnis RJ, Cybulski C, Neal DE, Nordestgaard BG, Nielsen SF, Batra J, Clements JA, Cancer BioResource AP, Grönberg H, Pashayan N, Travis RC, Park JY, Albanes D, Weinstein S, Mucci LA, Hunter DJ, Penney KL, Tangen CM, Hamilton RJ, Parent MÉ, Stanford JL, Koutros S, Wolk A, Sørensen KD, Blot WJ, Yeboah ED, Mensah JE, Lu YJ, Schaid DJ, Thibodeau SN, West CM, Maier C, Kibel AS, Cancel-Tassin G, Menegaux F, John EM, Grindedal EM, Khaw KT, Ingles SA, Vega A, Rosenstein BS, Teixeira MR, NC-LA PCaP Investigators, Kogevinas M, Cannon-Albright L, Huff C, Multigner L, Kaneva R, Leach RJ, Brenner H, Hsing AW, Kittles RA, Murphy AB, Logothetis CJ, Neuhausen SL, Isaacs WB, Nemesure B, Hennis AJ, Carpten J, Pandha H, De Ruyck K, Xu J, Razack A, Teo SH, Canary PASS Investigators, Newcomb LF, Fowke JH, Neslund-Dudas C, Rybicki BA, Gamulin M, Usmani N, Claessens F, Gago-Dominguez M, Castelao JE, Townsend PA, Crawford DC, Petrovics G, Casey G, Roobol MJ, Hu JF, Berndt SI, Van Den Eeden SK, Easton DF, Chanock SJ, Cook MB, Wiklund F, Witte JS, Eeles RA, Kote-Jarai Z, Watya S, Gaziano JM, Justice AC, Conti DV, Haiman CA. PMID: 37311464; PMCID: PMC10357473.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    19. Transcriptome-wide association study identifies novel candidate susceptibility genes for migraine. HGG Adv. 2023 Jul 13; 4(3):100211. Meyers TJ, Yin J, Herrera VA, Pressman AR, Hoffmann TJ, Schaefer C, Avins AL, Choquet H. PMID: 37415806; PMCID: PMC10319829.
      View in: PubMed   Mentions: Translation:HumansCells
    20. Genetically adjusted PSA levels for prostate cancer screening. Nat Med. 2023 Jun; 29(6):1412-1423. Kachuri L, Hoffmann TJ, Jiang Y, Berndt SI, Shelley JP, Schaffer KR, Machiela MJ, Freedman ND, Huang WY, Li SA, Easterlin R, Goodman PJ, Till C, Thompson I, Lilja H, Van Den Eeden SK, Chanock SJ, Haiman CA, Conti DV, Klein RJ, Mosley JD, Graff RE, Witte JS. PMID: 37264206; PMCID: PMC10287565.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    21. Evaluating Approaches for Constructing Polygenic Risk Scores for Prostate Cancer in Men of African and European Ancestry. medRxiv. 2023 May 15. Darst BF, Shen J, Madduri RK, Rodriguez AA, Xiao Y, Sheng X, Saunders EJ, Dadaev T, Brook MN, Hoffmann TJ, Muir K, Wan P, Le Marchand L, Wilkens L, Wang Y, Schleutker J, MacInnis RJ, Cybulski C, Neal DE, Nordestgaard BG, Nielsen SF, Batra J, Clements JA, Australian Prostate Cancer BioResource, Grönberg H, Pashayan N, Travis RC, Park JY, Albanes D, Weinstein S, Mucci LA, Hunter DJ, Penney KL, Tangen CM, Hamilton RJ, Parent MÉ, Stanford JL, Koutros S, Wolk A, Sørensen KD, Blot WJ, Yeboah ED, Mensah JE, Lu YJ, Schaid DJ, Thibodeau SN, West CM, Maier C, Kibel AS, Cancel-Tassin G, Menegaux F, John EM, Grindedal EM, Khaw KT, Ingles SA, Vega A, Rosenstein BS, Teixeira MR, NC-LA PCaP Investigators, Kogevinas M, Cannon-Albright L, Huff C, Multigner L, Kaneva R, Leach RJ, Brenner H, Hsing AW, Kittles RA, Murphy AB, Logothetis CJ, Neuhausen SL, Isaacs WB, Nemesure B, Hennis AJ, Carpten J, Pandha H, De Ruyck K, Xu J, Razack A, Teo SH, Canary PASS Investigators, Newcomb LF, Fowke JH, Neslund-Dudas C, Rybicki BA, Gamulin M, Usmani N, Claessens F, GagoDominguez M, Castelao JE, Townsend PA, Crawford DC, Petrovics G, Casey G, Roobol MJ, Hu JF, Berndt SI, Van Den Eeden SK, Easton DF, Chanock SJ, Cook MB, Wiklund F, Witte JS, Eeles RA, Kote-Jarai Z, Watya S, Gaziano JM, Justice AC, Conti DV, Haiman CA. PMID: 37292833; PMCID: PMC10246022.
      View in: PubMed   Mentions:
    22. Smartphone-Based Cancer and Obesity Prevention Education Program for Chinese Women (SCOPE): A Pilot RCT. Int J Environ Res Public Health. 2023 05 09; 20(10). Chen JL, Guo J, Zhong Q, Jiang Y, Zhang H, Mao P, Huang Q, Lin CX, Hoffmann TJ. PMID: 37239495; PMCID: PMC10218157.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    23. Transcriptome-Wide Association Analysis Identifies Novel Candidate Susceptibility Genes for Prostate-Specific Antigen Levels in Men Without Prostate Cancer. medRxiv. 2023 May 05. Chen DM, Dong R, Kachuri L, Hoffmann T, Jiang Y, Berndt SI, Shelley JP, Schaffer KR, Machiela MJ, Freedman ND, Huang WY, Li SA, Lilja H, Van Den Eeden SK, Chanock S, Haiman CA, Conti DV, Klein RJ, Mosley JD, Witte JS, Graff RE. PMID: 37205487; PMCID: PMC10187439.
      View in: PubMed   Mentions:
    24. Evaluation of premature ventricular complexes during in-hospital ECG monitoring as a predictor of ventricular tachycardia in an intensive care unit cohort. Res Nurs Health. 2023 08; 46(4):425-435. Suba S, Hoffmann TJ, Fleischmann KE, Schell-Chaple H, Marcus GM, Prasad P, Hu X, Badilini F, Pelter MM. PMID: 37127543; PMCID: PMC10351875.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    25. The impact of a structured onboarding program for newly hired nurse practitioners and physician assistants. J Am Assoc Nurse Pract. 2023 Apr 01; 35(4):265-271. Erickson M, Yee AM, Krauter R, Hoffmann T. PMID: 36857535.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    26. Rapid response nursing triage outcomes for COVID-19: factors associated with patient's participation in triage recommendations. BMC Med Inform Decis Mak. 2023 03 08; 23(1):47. Chen JL, Lin CX, Park M, Nutor JJ, de Lisser R, Hoffmann TJ, Kim HJ. PMID: 36890538; PMCID: PMC9994385.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    27. Evidence of Novel Susceptibility Variants for Prostate Cancer and a Multiancestry Polygenic Risk Score Associated with Aggressive Disease in Men of African Ancestry. Eur Urol. 2023 07; 84(1):13-21. Chen F, Madduri RK, Rodriguez AA, Darst BF, Chou A, Sheng X, Wang A, Shen J, Saunders EJ, Rhie SK, Bensen JT, Ingles SA, Kittles RA, Strom SS, Rybicki BA, Nemesure B, Isaacs WB, Stanford JL, Zheng W, Sanderson M, John EM, Park JY, Xu J, Wang Y, Berndt SI, Huff CD, Yeboah ED, Tettey Y, Lachance J, Tang W, Rentsch CT, Cho K, Mcmahon BH, Biritwum RB, Adjei AA, Tay E, Truelove A, Niwa S, Sellers TA, Yamoah K, Murphy AB, Crawford DC, Patel AV, Bush WS, Aldrich MC, Cussenot O, Petrovics G, Cullen J, Neslund-Dudas CM, Stern MC, Kote-Jarai Z, Govindasami K, Cook MB, Chokkalingam AP, Hsing AW, Goodman PJ, Hoffmann TJ, Drake BF, Hu JJ, Keaton JM, Hellwege JN, Clark PE, Jalloh M, Gueye SM, Niang L, Ogunbiyi O, Idowu MO, Popoola O, Adebiyi AO, Aisuodionoe-Shadrach OI, Ajibola HO, Jamda MA, Oluwole OP, Nwegbu M, Adusei B, Mante S, Darkwa-Abrahams A, Mensah JE, Diop H, Van Den Eeden SK, Blanchet P, Fowke JH, Casey G, Hennis AJ, Lubwama A, Thompson IM, Leach R, Easton DF, Preuss MH, Loos RJ, Gundell SM, Wan P, Mohler JL, Fontham ET, Smith GJ, Taylor JA, Srivastava S, Eeles RA, Carpten JD, Kibel AS, Multigner L, Parent MÉ, Menegaux F, Cancel-Tassin G, Klein EA, Andrews C, Rebbeck TR, Brureau L, Ambs S, Edwards TL, Watya S, Chanock SJ, Witte JS, Blot WJ, Michael Gaziano J, Justice AC, Conti DV, Haiman CA. PMID: 36872133; PMCID: PMC10424812.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    28. A Novel Approach to Assess Weekly Self-efficacy for Meeting Personalized Physical Activity Goals Via a Cellphone: 12-Week Longitudinal Study. JMIR Form Res. 2023 Jan 27; 7:e38877. Oh YJ, Hoffmann TJ, Fukuoka Y. PMID: 36705945; PMCID: PMC9919464.
      View in: PubMed   Mentions:
    29. A large genome-wide association study of QT interval length utilizing electronic health records. Genetics. 2022 11 30; 222(4). Hoffmann TJ, Lu M, Oni-Orisan A, Lee C, Risch N, Iribarren C. PMID: 36271874; PMCID: PMC9713425.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    30. Neonatal outcomes from a quasi-experimental clinical trial of Family Integrated Care versus Family-Centered Care for preterm infants in U.S. NICUs. BMC Pediatr. 2022 11 22; 22(1):674. Franck LS, Gay CL, Hoffmann TJ, Kriz RM, Bisgaard R, Cormier DM, Joe P, Lothe B, Sun Y. PMID: 36418988.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    31. Accurate Identification of Mucinous Pancreatic Cystic Lesions Using Small-Volume Analytes. J Surg Res. 2023 04; 284:322-331. Caiazza F, Conroy PC, Ivry SL, York T, Lin J, Hernandez S, Hoffmann TJ, Francis SS, Park WG, Yip-Schneider MT, Schmidt CM, Brand R, Craik CS, Kirkwood K. PMID: 36369049.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    32. Assessment of genetic susceptibility to multiple primary cancers through whole-exome sequencing in two large multi-ancestry studies. BMC Med. 2022 10 06; 20(1):332. Cavazos TB, Kachuri L, Graff RE, Nierenberg JL, Thai KK, Alexeeff S, Van Den Eeden S, Corley DA, Kushi LH, Regeneron Genetics Center, Hoffmann TJ, Ziv E, Habel LA, Jorgenson E, Sakoda LC, Witte JS. PMID: 36199081; PMCID: PMC9535845.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    33. The augmin complex architecture reveals structural insights into microtubule branching. Nat Commun. 2022 09 26; 13(1):5635. Zupa E, Würtz M, Neuner A, Hoffmann T, Rettel M, Böhler A, Vermeulen BJA, Eustermann S, Schiebel E, Pfeffer S. PMID: 36163468; PMCID: PMC9512787.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    34. Polygenic Risk Score and Statin Relative Risk Reduction for Primary Prevention of Myocardial Infarction in a Real-World Population. Clin Pharmacol Ther. 2022 11; 112(5):1070-1078. Oni-Orisan A, Haldar T, Cayabyab MAS, Ranatunga DK, Hoffmann TJ, Iribarren C, Krauss RM, Risch N. PMID: 35862449; PMCID: PMC10112337.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansPHPublic Health
    35. State-Level Policy Environments, Discrimination, and Victimization among Sexual and Gender Minority People. Int J Environ Res Public Health. 2022 08 11; 19(16). Clark KD, Lunn MR, Lev EM, Trujillo MA, Lubensky ME, Capriotti MR, Hoffmann TJ, Obedin-Maliver J, Flentje A. PMID: 36011548; PMCID: PMC9407724.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    36. 501 Meta-analyses of genome-wide association studies in multiethnic cohorts identify risk loci associated with hidradenitis suppurativa. Journal of Investigative Dermatology. 2022 Aug 1; 142(8):s85. Choquet CH, Yin YJ, Kim KY, Hoffmann HT, Saini SS, Shringarpure SS, Team T, Jorgenson JE, Asgari AM. .
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    37. Modest effect of statins on fasting glucose in a longitudinal electronic health record based cohort. Cardiovasc Diabetol. 2022 07 14; 21(1):132. Haldar T, Oni-Orisan A, Hoffmann TJ, Schaefer C, Iribarren C, Krauss RM, Medina MW, Risch N. PMID: 35836181; PMCID: PMC9284686.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    38. Ancestry- and sex-specific effects underlying inguinal hernia susceptibility identified in a multiethnic genome-wide association study meta-analysis. Hum Mol Genet. 2022 07 07; 31(13):2279-2293. Choquet H, Li W, Yin J, Bradley R, Hoffmann TJ, Nandakumar P, 23 and Me Research Team, Mostaedi R, Tian C, Ahituv N, Jorgenson E. PMID: 35022708; PMCID: PMC9262393.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    39. Session 6: Jos Willems Early Career Investigators CompetitionPremature ventricular complexes measured 24-hours prior to a ventricular tachycardia event are not associated with its occurrence in an intensive care unit cohort. Journal of Electrocardiology. 2022 Jul 1; 73:7-8. Suba SS, Hoffmann HT, Fleischmann FK, Schell-Chaple SH, Marcus MG, Prasad PP, Hu HX, Badilini BF, Pelter PM. .
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    40. Enablers and Barriers to HIV Services for Gay and Bisexual Men in the COVID-19 Era: Fusing Data Sets from Two Global Online Surveys Via File Concatenation With Adjusted Weights. JMIR Public Health Surveill. 2022 06 27; 8(6):e33538. Ayala G, Arreola S, Howell S, Hoffmann TJ, Santos GM. PMID: 35377321; PMCID: PMC9239571.
      View in: PubMed   Mentions: Translation:HumansPHPublic Health
    41. Common genetic variation associated with Mendelian disease severity revealed through cryptic phenotype analysis. Nat Commun. 2022 06 27; 13(1):3675. Blair DR, Hoffmann TJ, Shieh JT. PMID: 35760791; PMCID: PMC9237040.
      View in: PubMed   Mentions: 1     Fields:    
    42. Premature ventricular complexes during continuous electrocardiographic monitoring in the intensive care unit: Occurrence rates and associated patient characteristics. J Clin Nurs. 2023 Jul; 32(13-14):3469-3481. Suba S, Hoffmann TJ, Fleischmann KE, Schell-Chaple H, Prasad P, Marcus GM, Badilini F, Hu X, Pelter MM. PMID: 35712789.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    43. Abstract 1441: Genetic determinants of PSA levels improve prostate cancer screening. Cancer Research. 2022 Jun 15; 82(12_Supplement):1441-1441. Kachuri KL, Graff GR, Berndt BS, Machiela MM, Freedman FN, Chanock CS, Shelley SJ, Schaffer SK, Mosley MJ, Goodman GP, Till TC, Thompson TI, Klein KR, Van Den Eeden VS, Hoffmann HT, Witte WJ. .
      View in: Publisher Site   Mentions:
    44. Abstract 1446: Genetic risk factors for the development of multiple primary cancers. Cancer Research. 2022 Jun 15; 82(12_Supplement):1446-1446. Nierenberg NJ, Kachuri KL, Cavazos CT, Graff GR, Hoffmann HT, Zhang ZJ, Alexeeff AS, Habel HL, Corley CD, Van Den Eeden VS, Ziv ZE, Sakoda SL, Witte WJ. .
      View in: Publisher Site   Mentions:
    45. Association of Genetic Variants Linked to Late-Onset Alzheimer Disease With Cognitive Test Performance by Midlife. JAMA Netw Open. 2022 04 01; 5(4):e225491. Zimmerman SC, Brenowitz WD, Calmasini C, Ackley SF, Graff RE, Asiimwe SB, Staffaroni AM, Hoffmann TJ, Glymour MM. PMID: 35377426; PMCID: PMC8980909.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    46. Water Access and Adherence Intention Among HIV-Positive Pregnant Women and New Mothers Receiving Antiretroviral Therapy in Zambia. Front Public Health. 2022; 10:758447. Nutor JJ, Marquez S, Slaughter-Acey JC, Hoffmann TJ, DiMaria-Ghalili RA, Momplaisir F, Opong E, Jemmott LS. PMID: 35433591; PMCID: PMC9010721.
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    47. Healthcare Professionals' Attitudes toward Rapid Whole Genome Sequencing in Pediatric Acute Care. Children (Basel). 2022 Mar 04; 9(3). Franck LS, Scheurer-Monaghan A, Bupp CP, Fakhoury JD, Hoffmann TJ, Deshpandey M, Arenchild M, Dimmock DP. PMID: 35327729; PMCID: PMC8947383.
      View in: PubMed   Mentions: 1  
    48. Resilience, Physical Activity, and Depression in Women Living With HIV in the San Francisco Bay Area: A Cross-sectional Study. J Assoc Nurses AIDS Care. 2022 Mar-Apr 01; 33(2):202-210. Ambrose PR, Cuca YP, Baguso GN, Hoffmann TJ, Dawson-Rose C. PMID: 35195611.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    49. Agreement between respiratory rate measurement using a combined electrocardiographic derived method versus impedance from pneumography. J Electrocardiol. 2022 Mar-Apr; 71:16-24. Bawua LK, Miaskowski C, Suba S, Badilini F, Mortara D, Hu X, Rodway GW, Hoffmann TJ, Pelter MM. PMID: 35007832.
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    50. The Space in the Middle: Attitudes of Women's Health and Neonatal Nurses in the United States about Abortion. Womens Health Issues. 2022 Mar-Apr; 32(2):130-139. Alspaugh A, Mehra R, Coleman-Minahan K, Hoffmann TJ, Burton CW, Eagen-Torkko M, Bond TM, Franck LS, Olseon LC, Lanshaw N, Rychnovsky JD, McLemore MR. PMID: 34844851.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    51. Extension of Mendelian Randomization to Identify Earliest Manifestations of Alzheimer Disease: Association of Genetic Risk Score for Alzheimer Disease With Lower Body Mass Index by Age 50 Years. Am J Epidemiol. 2021 10 01; 190(10):2163-2171. Brenowitz WD, Zimmerman SC, Filshtein TJ, Yaffe K, Walter S, Hoffmann TJ, Jorgenson E, Whitmer RA, Whitmer RA, Glymour MM. PMID: 33843952; PMCID: PMC8576370.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    52. QT Interval Dynamics and Cardiovascular Outcomes: A Cohort Study in an Integrated Health Care Delivery System. J Am Heart Assoc. 2021 10 05; 10(19):e018513. Mantri N, Lu M, Zaroff JG, Risch N, Hoffmann T, Oni-Orisan A, Lee C, Jorgenson E, Iribarren C. PMID: 34581201; PMCID: PMC8649135.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    53. Torsade de pointes: A nested case-control study in an integrated healthcare delivery system. Ann Noninvasive Electrocardiol. 2022 01; 27(1):e12888. Mantri N, Lu M, Zaroff JG, Risch N, Hoffmann T, Oni-Orisan A, Lee C, Iribarren C. PMID: 34547155; PMCID: PMC8739596.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    54. Coffee Consumption and Incident Tachyarrhythmias: Reported Behavior, Mendelian Randomization, and Their Interactions. JAMA Intern Med. 2021 09 01; 181(9):1185-1193. Kim EJ, Hoffmann TJ, Nah G, Vittinghoff E, Delling F, Marcus GM. PMID: 34279564; PMCID: PMC8290332.
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    55. Effect of SLCO1B1 T521C on Statin-Related Myotoxicity With Use of Lovastatin and Atorvastatin. Clin Pharmacol Ther. 2021 09; 110(3):733-740. Lu B, Sun L, Seraydarian M, Hoffmann TJ, Medina MW, Risch N, Iribarren C, Krauss RM, Oni-Orisan A. PMID: 34114646; PMCID: PMC8376784.
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    56. New and sex-specific migraine susceptibility loci identified from a multiethnic genome-wide meta-analysis. Commun Biol. 2021 07 22; 4(1):864. Choquet H, Yin J, Jacobson AS, Horton BH, Hoffmann TJ, Jorgenson E, Avins AL, Pressman AR. PMID: 34294844; PMCID: PMC8298472.
      View in: PubMed   Mentions: 14  Translation:Humans
    57. A unified framework identifies new links between plasma lipids and diseases from electronic medical records across large-scale cohorts. Nat Genet. 2021 07; 53(7):972-981. Veturi Y, Lucas A, Bradford Y, Hui D, Dudek S, Theusch E, Verma A, Miller JE, Kullo I, Hakonarson H, Sleiman P, Schaid D, Stein CM, Edwards DRV, Feng Q, Wei WQ, Medina MW, Krauss RM, Hoffmann TJ, Risch N, Voight BF, Rader DJ, Ritchie MD. PMID: 34140684; PMCID: PMC8555954.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansPHPublic Health
    58. A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects. Nat Commun. 2021 06 14; 12(1):3595. Choquet H, Melles RB, Anand D, Yin J, Cuellar-Partida G, Wang W, 23andMe Research Team, Hoffmann TJ, Nair KS, Hysi PG, Lachke SA, Jorgenson E. PMID: 34127677; PMCID: PMC8203611.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimals
    59. Examining the relationship between interpersonal support and retention in HIV care among HIV+ nursing mothers in Uganda. BMC Res Notes. 2021 Jun 03; 14(1):224. Nutor JJ, Agbadi P, Hoffmann TJ, Anguyo G, Camlin CS. PMID: 34082834; PMCID: PMC8176692.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansPHPublic Health
    60. The Psychosocial Predictors and Day-Level Correlates of Substance Use Among Participants Recruited via an Online Crowdsourcing Platform in the United States: Daily Diary Study. JMIR Public Health Surveill. 2021 04 27; 7(4):e23872. Jain JP, Offer C, Rowe C, Turner C, Dawson-Rose C, Hoffmann T, Santos GM. PMID: 33904828; PMCID: PMC8114164.
      View in: PubMed   Mentions: Translation:Humans
    61. Mobile Health Intervention Promoting Physical Activity in Adults Post Cardiac Rehabilitation: Pilot Randomized Controlled Trial. JMIR Form Res. 2021 Apr 16; 5(4):e20468. Park LG, Elnaggar A, Lee SJ, Merek S, Hoffmann TJ, Von Oppenfeld J, Ignacio N, Whooley MA. PMID: 33861204; PMCID: PMC8087971.
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    62. Publisher Correction: Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction. Nat Genet. 2021 Mar; 53(3):413. Conti DV, Darst BF, Moss LC, Saunders EJ, Sheng X, Chou A, Schumacher FR, Olama AAA, Benlloch S, Dadaev T, Brook MN, Sahimi A, Hoffmann TJ, Takahashi A, Matsuda K, Momozawa Y, Fujita M, Muir K, Lophatananon A, Wan P, Le Marchand L, Wilkens LR, Stevens VL, Gapstur SM, Carter BD, Schleutker J, Tammela TLJ, Sipeky C, Auvinen A, Giles GG, Southey MC, MacInnis RJ, Cybulski C, Wokolorczyk D, Lubinski J, Neal DE, Donovan JL, Hamdy FC, Martin RM, Nordestgaard BG, Nielsen SF, Weischer M, Bojesen SE, Røder MA, Iversen P, Batra J, Chambers S, Moya L, Horvath L, Clements JA, Tilley W, Risbridger GP, Gronberg H, Aly M, Szulkin R, Eklund M, Nordström T, Pashayan N, Dunning AM, Ghoussaini M, Travis RC, Key TJ, Riboli E, Park JY, Sellers TA, Lin HY, Albanes D, Weinstein SJ, Mucci LA, Giovannucci E, Lindstrom S, Kraft P, Hunter DJ, Penney KL, Turman C, Tangen CM, Goodman PJ, Thompson IM, Hamilton RJ, Fleshner NE, Finelli A, Parent MÉ, Stanford JL, Ostrander EA, Geybels MS, Koutros S, Freeman LEB, Stampfer M, Wolk A, Håkansson N, Andriole GL, Hoover RN, Machiela MJ, Sørensen KD, Borre M, Blot WJ, Zheng W, Yeboah ED, Mensah JE, Lu YJ, Zhang HW, Feng N, Mao X, Wu Y, Zhao SC, Sun Z, Thibodeau SN, McDonnell SK, Schaid DJ, West CML, Burnet N, Barnett G, Maier C, Schnoeller T, Luedeke M, Kibel AS, Drake BF, Cussenot O, Cancel-Tassin G, Menegaux F, Truong T, Koudou YA, John EM, Grindedal EM, Maehle L, Khaw KT, Ingles SA, Stern MC, Vega A, Gómez-Caamaño A, Fachal L, Rosenstein BS, Kerns SL, Ostrer H, Teixeira MR, Paulo P, Brandão A, Watya S, Lubwama A, Bensen JT, Fontham ETH, Mohler J, Taylor JA, Kogevinas M, Llorca J, Castaño-Vinyals G, Cannon-Albright L, Teerlink CC, Huff CD, Strom SS, Multigner L, Blanchet P, Brureau L, Kaneva R, Slavov C, Mitev V, Leach RJ, Weaver B, Brenner H, Cuk K, Holleczek B, Saum KU, Klein EA, Hsing AW, Kittles RA, Murphy AB, Logothetis CJ, Kim J, Neuhausen SL, Steele L, Ding YC, Isaacs WB, Nemesure B, Hennis AJM, Carpten J, Pandha H, Michael A, De Ruyck K, De Meerleer G, Ost P, Xu J, Razack A, Lim J, Teo SH, Newcomb LF, Lin DW, Fowke JH, Neslund-Dudas C, Rybicki BA, Gamulin M, Lessel D, Kulis T, Usmani N, Singhal S, Parliament M, Claessens F, Joniau S, Van den Broeck T, Gago-Dominguez M, Castelao JE, Martinez ME, Larkin S, Townsend PA, Aukim-Hastie C, Bush WS, Aldrich MC, Crawford DC, Srivastava S, Cullen JC, Petrovics G, Casey G, Roobol MJ, Jenster G, van Schaik RHN, Hu JJ, Sanderson M, Varma R, McKean-Cowdin R, Torres M, Mancuso N, Berndt SI, Van Den Eeden SK, Easton DF, Chanock SJ, Cook MB, Wiklund F, Nakagawa H, Witte JS, Eeles RA, Kote-Jarai Z, Haiman CA. PMID: 33473200.
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    63. Cross-cancer evaluation of polygenic risk scores for 16 cancer types in two large cohorts. Nat Commun. 2021 02 12; 12(1):970. Graff RE, Cavazos TB, Thai KK, Kachuri L, Rashkin SR, Hoffman JD, Alexeeff SE, Blatchins M, Meyers TJ, Leong L, Tai CG, Emami NC, Corley DA, Kushi LH, Ziv E, Van Den Eeden SK, Jorgenson E, Hoffmann TJ, Habel LA, Witte JS, Sakoda LC. PMID: 33579919; PMCID: PMC7880989.
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    64. Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction. Nat Genet. 2021 01; 53(1):65-75. Conti DV, Darst BF, Moss LC, Saunders EJ, Sheng X, Chou A, Schumacher FR, Olama AAA, Benlloch S, Dadaev T, Brook MN, Sahimi A, Hoffmann TJ, Takahashi A, Matsuda K, Momozawa Y, Fujita M, Muir K, Lophatananon A, Wan P, Le Marchand L, Wilkens LR, Stevens VL, Gapstur SM, Carter BD, Schleutker J, Tammela TLJ, Sipeky C, Auvinen A, Giles GG, Southey MC, MacInnis RJ, Cybulski C, Wokolorczyk D, Lubinski J, Neal DE, Donovan JL, Hamdy FC, Martin RM, Nordestgaard BG, Nielsen SF, Weischer M, Bojesen SE, Røder MA, Iversen P, Batra J, Chambers S, Moya L, Horvath L, Clements JA, Tilley W, Risbridger GP, Gronberg H, Aly M, Szulkin R, Eklund M, Nordström T, Pashayan N, Dunning AM, Ghoussaini M, Travis RC, Key TJ, Riboli E, Park JY, Sellers TA, Lin HY, Albanes D, Weinstein SJ, Mucci LA, Giovannucci E, Lindstrom S, Kraft P, Hunter DJ, Penney KL, Turman C, Tangen CM, Goodman PJ, Thompson IM, Hamilton RJ, Fleshner NE, Finelli A, Parent MÉ, Stanford JL, Ostrander EA, Geybels MS, Koutros S, Freeman LEB, Stampfer M, Wolk A, Håkansson N, Andriole GL, Hoover RN, Machiela MJ, Sørensen KD, Borre M, Blot WJ, Zheng W, Yeboah ED, Mensah JE, Lu YJ, Zhang HW, Feng N, Mao X, Wu Y, Zhao SC, Sun Z, Thibodeau SN, McDonnell SK, Schaid DJ, West CML, Burnet N, Barnett G, Maier C, Schnoeller T, Luedeke M, Kibel AS, Drake BF, Cussenot O, Cancel-Tassin G, Menegaux F, Truong T, Koudou YA, John EM, Grindedal EM, Maehle L, Khaw KT, Ingles SA, Stern MC, Vega A, Gómez-Caamaño A, Fachal L, Rosenstein BS, Kerns SL, Ostrer H, Teixeira MR, Paulo P, Brandão A, Watya S, Lubwama A, Bensen JT, Fontham ETH, Mohler J, Taylor JA, Kogevinas M, Llorca J, Castaño-Vinyals G, Cannon-Albright L, Teerlink CC, Huff CD, Strom SS, Multigner L, Blanchet P, Brureau L, Kaneva R, Slavov C, Mitev V, Leach RJ, Weaver B, Brenner H, Cuk K, Holleczek B, Saum KU, Klein EA, Hsing AW, Kittles RA, Murphy AB, Logothetis CJ, Kim J, Neuhausen SL, Steele L, Ding YC, Isaacs WB, Nemesure B, Hennis AJM, Carpten J, Pandha H, Michael A, De Ruyck K, De Meerleer G, Ost P, Xu J, Razack A, Lim J, Teo SH, Newcomb LF, Lin DW, Fowke JH, Neslund-Dudas C, Rybicki BA, Gamulin M, Lessel D, Kulis T, Usmani N, Singhal S, Parliament M, Claessens F, Joniau S, Van den Broeck T, Gago-Dominguez M, Castelao JE, Martinez ME, Larkin S, Townsend PA, Aukim-Hastie C, Bush WS, Aldrich MC, Crawford DC, Srivastava S, Cullen JC, Petrovics G, Casey G, Roobol MJ, Jenster G, van Schaik RHN, Hu JJ, Sanderson M, Varma R, McKean-Cowdin R, Torres M, Mancuso N, Berndt SI, Van Den Eeden SK, Easton DF, Chanock SJ, Cook MB, Wiklund F, Nakagawa H, Witte JS, Eeles RA, Kote-Jarai Z, Haiman CA. PMID: 33398198; PMCID: PMC8148035.
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    65. Using Genetic Information to Explore Whether Preclinical Alzheimer’s Disease Affects Hearing Difficulty. Innovation in Aging. 2020 Dec 16; 4(Suppl 1):805-805. Brenowitz BW, Filshtein FT, Yaffe YK, Walter WS, Hoffmann HT, Jorgenson JE, Whitmer WR, Glymour GM. .
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    66. Genetic ancestry, skin pigmentation, and the risk of cutaneous squamous cell carcinoma in Hispanic/Latino and non-Hispanic white populations. Commun Biol. 2020 12 14; 3(1):765. Jorgenson E, Choquet H, Yin J, Hoffmann TJ, Banda Y, Kvale MN, Risch N, Schaefer C, Asgari MM. PMID: 33318654; PMCID: PMC7736583.
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    67. A Large-Scale Association Study Detects Novel Rare Variants, Risk Genes, Functional Elements, and Polygenic Architecture of Prostate Cancer Susceptibility. Cancer Res. 2021 04 01; 81(7):1695-1703. Emami NC, Cavazos TB, Rashkin SR, Cario CL, Graff RE, Tai CG, Mefford JA, Kachuri L, Wan E, Wong S, Aaronson D, Presti J, Habel LA, Shan J, Ranatunga DK, Chao CR, Ghai NR, Jorgenson E, Sakoda LC, Kvale MN, Kwok PY, Schaefer C, Risch N, Hoffmann TJ, Van Den Eeden SK, Witte JS. PMID: 33293427; PMCID: PMC8137514.
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    68. Functional hearing loss as a marker for early Alzheimer’s disease and dementia: Exploring the potential for reverse causation. Alzheimer's & Dementia. 2020 Dec 7; 16(S10). Brenowitz BW, Filshtein FT, Yaffe YK, Walter WS, Ackley AS, Hoffmann HT, Jorgenson JE, Whitmer WR, Glymour GM. .
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    69. ASSOCIATION OF HIV INFECTION WITH CLINICAL AND LABORATORY CHARACTERISTICS OF SICKLE CELL DISEASE. Hematology Transfusion and Cell Therapy. 2020 Nov 1; 42:36. Belisário BA, Blatyta BP, Vivanco VD, Oliveira OC, Carneiro-Proietti CA, Sabino SE, Almeida-Neto AC, Loureiro LP, Máximo MC, Mateos MS, Flor-Park FM, Rodrigues RD, Mota MR, Gonçalez GT, Hoffmann HT, Kelly KS, Custer CB. .
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    70. Nintedanib plus mFOLFOX6 as second-line treatment of metastatic, chemorefractory colorectal cancer: The randomised, placebo-controlled, phase II TRICC-C study (AIO-KRK-0111). Int J Cancer. 2021 03 15; 148(6):1428-1437. Ettrich TJ, Perkhofer L, Decker T, Hofheinz RD, Heinemann V, Hoffmann T, Hebart HF, Herrmann T, Hannig CV, Büchner-Steudel P, Güthle M, Hermann PC, Berger AW, Seufferlein T. PMID: 32930387.
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    71. Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts. Nat Commun. 2020 09 04; 11(1):4423. Rashkin SR, Graff RE, Kachuri L, Thai KK, Alexeeff SE, Blatchins MA, Cavazos TB, Corley DA, Emami NC, Hoffman JD, Jorgenson E, Kushi LH, Meyers TJ, Van Den Eeden SK, Ziv E, Habel LA, Hoffmann TJ, Sakoda LC, Witte JS. PMID: 32887889; PMCID: PMC7473862.
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    72. Association of genetic risk for Alzheimer disease and hearing impairment. Neurology. 2020 10 20; 95(16):e2225-e2234. Brenowitz WD, Filshtein TJ, Yaffe K, Walter S, Ackley SF, Hoffmann TJ, Jorgenson E, Whitmer RA, Whitmer RA, Glymour MM. PMID: 32878991; PMCID: PMC7713783.
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    73. Association of HIV infection with clinical and laboratory characteristics of sickle cell disease. BMC Infect Dis. 2020 Aug 27; 20(1):638. Belisário AR, Blatyta PF, Vivanco D, Oliveira CDL, Carneiro-Proietti AB, Sabino EC, de Almeida-Neto C, Loureiro P, Máximo C, de Oliveira Garcia Mateos S, Flor-Park MV, de Oliveira Werneck Rodrigues D, Afonso Mota R, Gonçalez TT, Hoffmann TJ, Kelly S, Custer B, Recipient Epidemiology and Donor Evaluation Study-III (REDS-III) International Component Brazil. PMID: 32854639; PMCID: PMC7457248.
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    74. Attitudes of California Registered Nurses About Abortion. J Obstet Gynecol Neonatal Nurs. 2020 09; 49(5):475-486. Swartz A, Hoffmann TJ, Cretti E, Burton CW, Eagen-Torkko M, Levi AJ, Aztlan EA, McLemore MR. PMID: 32783889.
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    75. Analysis of putative cis-regulatory elements regulating blood pressure variation. Hum Mol Genet. 2020 07 21; 29(11):1922-1932. Nandakumar P, Lee D, Hoffmann TJ, Ehret GB, Arking D, Ranatunga D, Li M, Grove ML, Boerwinkle E, Schaefer C, Kwok PY, Iribarren C, Risch N, Chakravarti A. PMID: 32436959; PMCID: PMC7372556.
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    76. Meta-Analysis of 26 638 Individuals Identifies Two Genetic Loci Associated With Left Ventricular Ejection Fraction. Circ Genom Precis Med. 2020 08; 13(4):e002804. Choquet H, Thai KK, Jiang C, Ranatunga DK, Hoffmann TJ, Go AS, Lindsay AC, Ehm MG, Waterworth DM, Risch N, Schaefer C. PMID: 32605384; PMCID: PMC7446727.
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    77. A multiethnic genome-wide analysis of 44,039 individuals identifies 41 new loci associated with central corneal thickness. Commun Biol. 2020 06 11; 3(1):301. Choquet H, Melles RB, Yin J, Hoffmann TJ, Thai KK, Kvale MN, Banda Y, Hardcastle AJ, Tuft SJ, Glymour MM, Schaefer C, Risch N, Nair KS, Hysi PG, Jorgenson E. PMID: 32528159; PMCID: PMC7289804.
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    78. The impact of adjusting for baseline in pharmacogenomic genome-wide association studies of quantitative change. NPJ Genom Med. 2020; 5:1. Oni-Orisan A, Haldar T, Ranatunga DK, Medina MW, Schaefer C, Krauss RM, Iribarren C, Risch N, Hoffmann TJ. PMID: 31969989; PMCID: PMC6965183.
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    79. Using a genetic risk score to estimate the earliest age of Alzheimer's disease-related physiologic change in Body Mass Index. medRxiv. 2019 Dec 4; 19013441. Brenowitz BW, Zimmerman ZS, Filshtein FT, Yaffe YK, Walter WS, Hoffmann HT, Jorgenson JE, Whitmer WR, Glymour GM. .
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    80. Association of Genetic Variants With Primary Open-Angle Glaucoma Among Individuals With African Ancestry. JAMA. 2019 11 05; 322(17):1682-1691. Genetics of Glaucoma in People of African Descent (GGLAD) Consortium, Hauser MA, Allingham RR, Aung T, Van Der Heide CJ, Taylor KD, Rotter JI, Wang SJ, Bonnemaijer PWM, Williams SE, Abdullahi SM, Abu-Amero KK, Anderson MG, Akafo S, Alhassan MB, Asimadu I, Ayyagari R, Bakayoko S, Nyamsi PB, Bowden DW, Bromley WC, Budenz DL, Carmichael TR, Challa P, Chen YI, Chuka-Okosa CM, Cooke Bailey JN, Costa VP, Cruz DA, DuBiner H, Ervin JF, Feldman RM, Flamme-Wiese M, Gaasterland DE, Garnai SJ, Girkin CA, Guirou N, Guo X, Haines JL, Hammond CJ, Herndon L, Hoffmann TJ, Hulette CM, Hydara A, Igo RP, Jorgenson E, Kabwe J, Kilangalanga NJ, Kizor-Akaraiwe N, Kuchtey RW, Lamari H, Li Z, Liebmann JM, Liu Y, Loos RJF, Melo MB, Moroi SE, Msosa JM, Mullins RF, Nadkarni G, Napo A, Ng MCY, Nunes HF, Obeng-Nyarkoh E, Okeke A, Okeke S, Olaniyi O, Olawoye O, Oliveira MB, Pasquale LR, Perez-Grossmann RA, Pericak-Vance MA, Qin X, Ramsay M, Resnikoff S, Richards JE, Schimiti RB, Sim KS, Sponsel WE, Svidnicki PV, Thiadens AAHJ, Uche NJ, van Duijn CM, de Vasconcellos JPC, Wiggs JL, Zangwill LM, Risch N, Milea D, Ashaye A, Klaver CCW, Weinreb RN, Ashley Koch AE, Fingert JH, Khor CC. PMID: 31688885; PMCID: PMC6865235.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    81. Rare Protein-Altering Telomere-related Gene Variants in Patients with Chronic Hypersensitivity Pneumonitis. Am J Respir Crit Care Med. 2019 11 01; 200(9):1154-1163. Ley B, Torgerson DG, Oldham JM, Adegunsoye A, Liu S, Li J, Elicker BM, Henry TS, Golden JA, Jones KD, Dressen A, Yaspan BL, Arron JR, Noth I, Hoffmann TJ, Wolters PJ. PMID: 31268371; PMCID: PMC6888660.
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    82. Author Correction: Association of imputed prostate cancer transcriptome with disease risk reveals novel mechanisms. Nat Commun. 2019 Aug 28; 10(1):3948. Emami NC, Kachuri L, Meyers TJ, Das R, Hoffman JD, Hoffmann TJ, Hu D, Shan J, Feng FY, Ziv E, Van Den Eeden SK, Witte JS. PMID: 31462633; PMCID: PMC6713745.
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    83. Genetic ancestry does not explain increased atopic dermatitis susceptibility or worse disease control among African American subjects in 2 large US cohorts. J Allergy Clin Immunol. 2020 01; 145(1):192-198.e11. Abuabara K, You Y, Margolis DJ, Hoffmann TJ, Risch N, Jorgenson E. PMID: 31369801; PMCID: PMC6949407.
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    84. Association of imputed prostate cancer transcriptome with disease risk reveals novel mechanisms. Nat Commun. 2019 07 15; 10(1):3107. Emami NC, Kachuri L, Meyers TJ, Das R, Hoffman JD, Hoffmann TJ, Hu D, Shan J, Feng FY, Ziv E, Van Den Eeden SK, Witte JS. PMID: 31308362; PMCID: PMC6629701.
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    85. A genome-wide association study of prostate cancer in Latinos. Int J Cancer. 2020 04 01; 146(7):1819-1826. Du Z, Hopp H, Ingles SA, Huff C, Sheng X, Weaver B, Stern M, Hoffmann TJ, John EM, Van Den Eeden SK, Strom S, Leach RJ, Thompson IM, Witte JS, Conti DV, Haiman CA. PMID: 31226226; PMCID: PMC7028127.
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    86. USING GENETIC INFORMATION TO IDENTIFY THE EARLIEST MANIFESTATIONS OF ALZHEIMER’S DISEASE: GENETIC RISK SCORE FOR ALZHEIMER’S DISEASE PREDICTS LOWER BMI BY AGE 58. Alzheimer's & Dementia. 2019 Jul 1; 15(7):p903. Brenowitz BW, Filshtein FT, Yaffe YK, Walter WS, Hoffmann HT, Jorgenson JE, Whitmer WR, Glymour GM. .
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    87. Telomere length and socioeconomic status at neighborhood and individual levels among 80,000 adults in the Genetic Epidemiology Research on Adult Health and Aging cohort. Environ Epidemiol. 2019 Jun; 3(3):e049. Alexeeff SE, Schaefer CA, Kvale MN, Shan J, Blackburn EH, Risch N, Ranatunga DK, Jorgenson E, Hoffmann TJ, Sakoda LC, Quesenberry CP, Van Den Eeden SK. PMID: 33778338; PMCID: PMC7939422.
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    88. Reply to Liu et al.: Tissue specificity of SIM1 gene expression and erectile dysfunction. Proc Natl Acad Sci U S A. 2019 02 26; 116(9):3349-3350. Jorgenson E, Matharu N, Palmer MR, Yin J, Shan J, Hoffmann TJ, Thai KK, Zhou X, Hotaling JM, Jarvik GP, Ahituv N, Wessells H, Van Den Eeden SK. PMID: 30755537; PMCID: PMC6397520.
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    89. SU23 ASSOCIATIONS OF POLYGENIC RISK OF SCHIZOPHRENIA AND MAJOR DEPRESSION IN STUDIES OF BIPOLAR DISORDER AND MAJOR DEPRESSION. European Neuropsychopharmacology. 2019 Jan 1; 29:s899-s900. Schaefer SC, Thai TK, Jorgenson JE, Banda BY, Hoffmann HT, Kvale KM, Risch RN. .
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    90. Genetic variation in the SIM1 locus is associated with erectile dysfunction. Proc Natl Acad Sci U S A. 2018 10 23; 115(43):11018-11023. Jorgenson E, Matharu N, Palmer MR, Yin J, Shan J, Hoffmann TJ, Thai KK, Zhou X, Hotaling JM, Jarvik GP, Ahituv N, Wessells H, Van Den Eeden SK. PMID: 30297428; PMCID: PMC6205494.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    91. Characterization of Statin Low-Density Lipoprotein Cholesterol Dose-Response Using Electronic Health Records in a Large Population-Based Cohort. Circ Genom Precis Med. 2018 09; 11(9):e002043. Oni-Orisan A, Hoffmann TJ, Ranatunga D, Medina MW, Jorgenson E, Schaefer C, Krauss RM, Iribarren C, Risch N. PMID: 30354326; PMCID: PMC6214660.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    92. A Large Multiethnic Genome-Wide Association Study of Adult Body Mass Index Identifies Novel Loci. Genetics. 2018 10; 210(2):499-515. Hoffmann TJ, Choquet H, Yin J, Banda Y, Kvale MN, Glymour M, Schaefer C, Risch N, Jorgenson E. PMID: 30108127; PMCID: PMC6216593.
      View in: PubMed   Mentions: 77     Fields:    Translation:Humans
    93. EVALUATING REVERSE CAUSATION BETWEEN DEMENTIA AND HEARING IMPAIRMENT USING A GENETIC RISK SCORE FOR ALZHEIMER’S DISEASE. Alzheimer's & Dementia. 2018 Jul 1; 14(7):p1012-p1013. Brenowitz BW, Filshtein FT, Hoffmann HT, Yaffe YK, Jorgenson JE, Whitmer WR, Glymour GM. .
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    94. A multiethnic genome-wide association study of primary open-angle glaucoma identifies novel risk loci. Nat Commun. 2018 06 11; 9(1):2278. Choquet H, Paylakhi S, Kneeland SC, Thai KK, Hoffmann TJ, Yin J, Kvale MN, Banda Y, Tolman NG, Williams PA, Schaefer C, Melles RB, Risch N, John SWM, Nair KS, Jorgenson E. PMID: 29891935; PMCID: PMC5995837.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansAnimalsCells
    95. A large electronic-health-record-based genome-wide study of serum lipids. Nat Genet. 2018 03; 50(3):401-413. Hoffmann TJ, Theusch E, Haldar T, Ranatunga DK, Jorgenson E, Medina MW, Kvale MN, Kwok PY, Schaefer C, Krauss RM, Iribarren C, Risch N. PMID: 29507422; PMCID: PMC5942247.
      View in: PubMed   Mentions: 133     Fields:    Translation:Humans
    96. A large multi-ethnic genome-wide association study identifies novel genetic loci for intraocular pressure. Nat Commun. 2017 12 13; 8(1):2108. Choquet H, Thai KK, Yin J, Hoffmann TJ, Kvale MN, Banda Y, Schaefer C, Risch N, Nair KS, Melles R, Jorgenson E. PMID: 29235454; PMCID: PMC5727399.
      View in: PubMed   Mentions: 45     Fields:    Translation:Humans
    97. Identification of Pleiotropic Cancer Susceptibility Variants from Genome-Wide Association Studies Reveals Functional Characteristics. Cancer Epidemiol Biomarkers Prev. 2018 01; 27(1):75-85. Wu YH, Graff RE, Passarelli MN, Hoffman JD, Ziv E, Hoffmann TJ, Witte JS. PMID: 29150481; PMCID: PMC5760292.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    98. Two Novel Susceptibility Loci for Prostate Cancer in Men of African Ancestry. J Natl Cancer Inst. 2017 08 01; 109(8). Conti DV, Wang K, Sheng X, Bensen JT, Hazelett DJ, Cook MB, Ingles SA, Kittles RA, Strom SS, Rybicki BA, Nemesure B, Isaacs WB, Stanford JL, Zheng W, Sanderson M, John EM, Park JY, Xu J, Stevens VL, Berndt SI, Huff CD, Wang Z, Yeboah ED, Tettey Y, Biritwum RB, Adjei AA, Tay E, Truelove A, Niwa S, Sellers TA, Yamoah K, Murphy AB, Crawford DC, Gapstur SM, Bush WS, Aldrich MC, Cussenot O, Petrovics G, Cullen J, Neslund-Dudas C, Stern MC, Jarai ZK, Govindasami K, Chokkalingam AP, Hsing AW, Goodman PJ, Hoffmann T, Drake BF, Hu JJ, Clark PE, Van Den Eeden SK, Blanchet P, Fowke JH, Casey G, Hennis AJM, Han Y, Lubwama A, Thompson IM, Leach R, Easton DF, Schumacher F, Van den Berg DJ, Gundell SM, Stram A, Wan P, Xia L, Pooler LC, Mohler JL, Fontham ETH, Smith GJ, Taylor JA, Srivastava S, Eeles RA, Carpten J, Kibel AS, Multigner L, Parent ME, Menegaux F, Cancel-Tassin G, Klein EA, Brureau L, Stram DO, Watya S, Chanock SJ, Witte JS, Blot WJ, Henderson BE, Haiman CA, PRACTICAL/ELLIPSE Consortium. PMID: 29117387; PMCID: PMC5448553.
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    99. Abstract 1316: Germline genetic signals across multiple aggressive prostate cancer phenotypes. Epidemiology. 2017 Jul 1; 1316-1316. Tai TC, Emami EN, Hoffmann HT, Sakoda SL, Jorgenson JE, Habel HL, Shan SJ, Ranatunga RD, Chao CC, Ghai GN, Aaronson AD, Presti PJ, Schaefer SC, Risch RN, Eeden ES, Witte WJ. .
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    100. Abstract 1310: Identification of pleiotropic cancer susceptibility variants from genome-wide association studies reveals functional characteristics. Epidemiology. 2017 Jul 1; 1310-1310. Wu WY, Graff GR, Passarelli PM, Hoffmann HT, Ziv ZE, Witte WJ. .
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    101. Birth weight interacts with a functional variant of the oxytocin receptor gene (OXTR) to predict executive functioning in children. Dev Psychopathol. 2018 02; 30(1):203-211. Wade M, Prime H, Hoffmann TJ, Schmidt LA, O'Connor TG, Jenkins JM. PMID: 28511728.
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    102. Genetic contributors to variation in alcohol consumption vary by race/ethnicity in a large multi-ethnic genome-wide association study. Mol Psychiatry. 2017 09; 22(9):1359-1367. Jorgenson E, Thai KK, Hoffmann TJ, Sakoda LC, Kvale MN, Banda Y, Schaefer C, Risch N, Mertens J, Weisner C, Choquet H. PMID: 28485404; PMCID: PMC5568932.
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    103. Validation of Electronic Health Records for the Assessment of Statin Dosing In Research. Journal of Clinical Lipidology. 2017 May 1; 11(3):836-837. Oni-Orisan OA, Hoffmann HT, Medina MM, Jorgenson JE, Schaefer SC, Krauss KR, Iribarren IC, Risch RN. .
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    104. Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer. Nat Commun. 2017 01 31; 8:14248. Hoffmann TJ, Passarelli MN, Graff RE, Emami NC, Sakoda LC, Jorgenson E, Habel LA, Shan J, Ranatunga DK, Quesenberry CP, Chao CR, Ghai NR, Aaronson D, Presti J, Nordström T, Wang Z, Berndt SI, Chanock SJ, Mosley JD, Klein RJ, Middha M, Lilja H, Melander O, Kvale MN, Kwok PY, Schaefer C, Risch N, Van Den Eeden SK, Witte JS. PMID: 28139693; PMCID: PMC5290311.
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    105. Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation. Nat Genet. 2017 01; 49(1):54-64. Hoffmann TJ, Ehret GB, Nandakumar P, Ranatunga D, Schaefer C, Kwok PY, Iribarren C, Chakravarti A, Risch N. PMID: 27841878; PMCID: PMC5370207.
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    106. A Large Genome-Wide Association Study of Age-Related Hearing Impairment Using Electronic Health Records. PLoS Genet. 2016 Oct; 12(10):e1006371. Hoffmann TJ, Keats BJ, Yoshikawa N, Schaefer C, Risch N, Lustig LR. PMID: 27764096; PMCID: PMC5072625.
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    107. Evaluation of a novel point-of-care test for active matrix metalloproteinase-8: agreement between qualitative and quantitative measurements and relation to periodontal inflammation. J Periodontal Res. 2017 Apr; 52(2):277-284. Lorenz K, Keller T, Noack B, Freitag A, Netuschil L, Hoffmann T. PMID: 27214099.
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    108. Oxytocin and vasopressin hormone genes in children's externalizing problems: A cognitive endophenotype approach. Horm Behav. 2016 06; 82:78-86. Wade M, Hoffmann TJ, Knafo-Noam A, O'Connor TG, Jenkins JM. PMID: 27155104.
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    109. Mutational Landscape of Aggressive Prostate Tumors in African American Men. Cancer Res. 2016 04 01; 76(7):1860-8. Lindquist KJ, Paris PL, Hoffmann TJ, Cardin NJ, Kazma R, Mefford JA, Simko JP, Ngo V, Chen Y, Levin AM, Chitale D, Helfand BT, Catalona WJ, Rybicki BA, Witte JS. PMID: 26921337; PMCID: PMC4772140.
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    110. Impact of genetic variants on the upstream efficacy of renin-angiotensin system inhibitors for the prevention of atrial fibrillation. Am Heart J. 2016 05; 175:9-17. Roberts JD, Dewland TA, Glidden DV, Hoffmann TJ, Arking DE, Chen LY, Psaty BM, Olgin JE, Alonso A, Heckbert SR, Marcus GM. PMID: 27179719; PMCID: PMC4873713.
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    111. Identification of Susceptibility Loci for Cutaneous Squamous Cell Carcinoma. J Invest Dermatol. 2016 05; 136(5):930-937. Asgari MM, Wang W, Ioannidis NM, Itnyre J, Hoffmann T, Jorgenson E, Whittemore AS. PMID: 26829030; PMCID: PMC4842155.
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    112. Common coding variants in the HLA-DQB1 region confer susceptibility to age-related macular degeneration. Eur J Hum Genet. 2016 07; 24(7):1049-55. Jorgenson E, Melles RB, Hoffmann TJ, Jia X, Sakoda LC, Kvale MN, Banda Y, Schaefer C, Risch N, Shen L. PMID: 26733291; PMCID: PMC5070898.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    113. Genome-Wide Estimates of Heritability for Social Demographic Outcomes. Biodemography Soc Biol. 2016; 62(1):1-18. Domingue BW, Wedow R, Conley D, McQueen M, Hoffmann TJ, Boardman JD. PMID: 27050030; PMCID: PMC4918078.
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    114. Strategies for Imputing and Analyzing Rare Variants in Association Studies. Trends Genet. 2015 Oct; 31(10):556-563. Hoffmann TJ, Witte JS. PMID: 26450338; PMCID: PMC4600126.
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    115. Homogeneous matrix deposition on dried agar for MALDI imaging mass spectrometry of microbial cultures. J Am Soc Mass Spectrom. 2015 Nov; 26(11):1959-62. Hoffmann T, Dorrestein PC. PMID: 26297185.
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    116. Differences in the Genetic Susceptibility to Age-Related Macular Degeneration Clinical Subtypes. Invest Ophthalmol Vis Sci. 2015 Jul; 56(8):4290-9. Shen L, Hoffmann TJ, Melles RB, Sakoda LC, Kvale MN, Banda Y, Schaefer C, Risch N, Jorgenson E. PMID: 26176866; PMCID: PMC4509058.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    117. Characterizing Race/Ethnicity and Genetic Ancestry for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort. Genetics. 2015 Aug; 200(4):1285-95. Banda Y, Kvale MN, Hoffmann TJ, Hesselson SE, Ranatunga D, Tang H, Sabatti C, Croen LA, Dispensa BP, Henderson M, Iribarren C, Jorgenson E, Kushi LH, Ludwig D, Olberg D, Quesenberry CP, Rowell S, Sadler M, Sakoda LC, Sciortino S, Shen L, Smethurst D, Somkin CP, Van Den Eeden SK, Walter L, Whitmer RA, Whitmer RA, Kwok PY, Schaefer C, Risch N. PMID: 26092716; PMCID: PMC4574246.
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    118. Automated Assay of Telomere Length Measurement and Informatics for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort. Genetics. 2015 Aug; 200(4):1061-72. Lapham K, Kvale MN, Lin J, Connell S, Croen LA, Dispensa BP, Fang L, Hesselson S, Hoffmann TJ, Iribarren C, Jorgenson E, Kushi LH, Ludwig D, Matsuguchi T, McGuire WB, Miles S, Quesenberry CP, Rowell S, Sadler M, Sakoda LC, Smethurst D, Somkin CP, Van Den Eeden SK, Walter L, Whitmer RA, Whitmer RA, Kwok PY, Risch N, Schaefer C, Blackburn EH. PMID: 26092717; PMCID: PMC4574243.
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    119. Genotyping Informatics and Quality Control for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort. Genetics. 2015 Aug; 200(4):1051-60. Kvale MN, Hesselson S, Hoffmann TJ, Cao Y, Chan D, Connell S, Croen LA, Dispensa BP, Eshragh J, Finn A, Gollub J, Iribarren C, Jorgenson E, Kushi LH, Lao R, Lu Y, Ludwig D, Mathauda GK, McGuire WB, Mei G, Miles S, Mittman M, Patil M, Quesenberry CP, Ranatunga D, Rowell S, Sadler M, Sakoda LC, Shapero M, Shen L, Shenoy T, Smethurst D, Somkin CP, Van Den Eeden SK, Walter L, Wan E, Webster T, Whitmer RA, Whitmer RA, Wong S, Zau C, Zhan Y, Schaefer C, Kwok PY, Risch N. PMID: 26092718; PMCID: PMC4574249.
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    120. A large multiethnic genome-wide association study of prostate cancer identifies novel risk variants and substantial ethnic differences. Cancer Discov. 2015 Aug; 5(8):878-91. Hoffmann TJ, Van Den Eeden SK, Sakoda LC, Jorgenson E, Habel LA, Graff RE, Passarelli MN, Cario CL, Emami NC, Chao CR, Ghai NR, Shan J, Ranatunga DK, Quesenberry CP, Aaronson D, Presti J, Wang Z, Berndt SI, Chanock SJ, McDonnell SK, French AJ, Schaid DJ, Thibodeau SN, Li Q, Freedman ML, Penney KL, Mucci LA, Haiman CA, Henderson BE, Seminara D, Kvale MN, Kwok PY, Schaefer C, Risch N, Witte JS. PMID: 26034056; PMCID: PMC4527942.
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    121. Detecting gene-environment interactions in human birth defects: Study designs and statistical methods. Birth Defects Res A Clin Mol Teratol. 2015 Aug; 103(8):692-702. Tai CG, Graff RE, Liu J, Passarelli MN, Mefford JA, Shaw GM, Hoffmann TJ, Witte JS. PMID: 26010994; PMCID: PMC4537677.
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    122. Gene-environment interaction between the oxytocin receptor (OXTR) gene and parenting behaviour on children's theory of mind. Soc Cogn Affect Neurosci. 2015 Dec; 10(12):1749-57. Wade M, Hoffmann TJ, Jenkins JM. PMID: 25977357; PMCID: PMC4666114.
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    123. Genome-wide association study identifies ABCG2 (BCRP) as an allopurinol transporter and a determinant of drug response. Clin Pharmacol Ther. 2015 May; 97(5):518-25. Wen CC, Yee SW, Liang X, Hoffmann TJ, Kvale MN, Banda Y, Jorgenson E, Schaefer C, Risch N, Giacomini KM. PMID: 25676789; PMCID: PMC4479153.
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    124. Replication and heritability of prostate cancer risk variants: impact of population-specific factors. Cancer Epidemiol Biomarkers Prev. 2015 Jun; 24(6):938-43. Virlogeux V, Graff RE, Hoffmann TJ, Witte JS. PMID: 25809866.
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    125. Imputation of the rare HOXB13 G84E mutation and cancer risk in a large population-based cohort. PLoS Genet. 2015 Jan; 11(1):e1004930. Hoffmann TJ, Sakoda LC, Shen L, Jorgenson E, Habel LA, Liu J, Kvale MN, Asgari MM, Banda Y, Corley D, Kushi LH, Quesenberry CP, Schaefer C, Van Den Eeden SK, Risch N, Witte JS. PMID: 25629170; PMCID: PMC4309593.
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    126. Familial recurrence of autism spectrum disorder: evaluating genetic and environmental contributions. Am J Psychiatry. 2014 Nov 01; 171(11):1206-13. Risch N, Hoffmann TJ, Anderson M, Croen LA, Grether JK, Windham GC. PMID: 24969362.
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    127. Genome-wide discovery of drug-dependent human liver regulatory elements. PLoS Genet. 2014 Oct; 10(10):e1004648. Smith RP, Eckalbar WL, Morrissey KM, Luizon MR, Hoffmann TJ, Sun X, Jones SL, Force Aldred S, Ramamoorthy A, Desta Z, Liu Y, Skaar TC, Trinklein ND, Giacomini KM, Ahituv N. PMID: 25275310; PMCID: PMC4183418.
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    128. Evidence of reproductive stoppage in families with autism spectrum disorder: a large, population-based cohort study. JAMA Psychiatry. 2014 Aug; 71(8):943-51. Hoffmann TJ, Windham GC, Anderson M, Croen LA, Grether JK, Risch N. PMID: 24942798.
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    129. Association between the oxytocin receptor (OXTR) gene and children's social cognition at 18 months. Genes Brain Behav. 2014 Sep; 13(7):603-10. Wade M, Hoffmann TJ, Wigg K, Jenkins JM. PMID: 24916666.
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    130. Genome-wide association and admixture analysis of glaucoma in the Women's Health Initiative. Hum Mol Genet. 2014 Dec 15; 23(24):6634-43. Hoffmann TJ, Tang H, Thornton TA, Caan B, Haan M, Millen AE, Thomas F, Risch N. PMID: 25027321; PMCID: PMC4240199.
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    131. Association between the arginine vasopressin receptor 1A (AVPR1A) gene and preschoolers' executive functioning. Brain Cogn. 2014 Oct; 90:116-23. Wade M, Hoffmann TJ, Jenkins JM. PMID: 25016245.
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    132. Comparison of periodontal conditions among three elderly populations in Japan and Germany. J Clin Periodontol. 2014 Jul; 41(7):633-42. Hirotomi T, Kocher T, Yoshihara A, Biffar R, Micheelis W, Hoffmann T, Miyazaki H, Holtfreter B. PMID: 24797068.
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    133. Copy number variation in bronchopulmonary dysplasia. Am J Med Genet A. 2014 Oct; 164A(10):2672-5. Hoffmann TJ, Shaw GM, Stevenson DK, Wang H, Quaintance CC, Oehlert J, Jelliffe-Pawlowski LL, Gould JB, Witte JS, O'Brodovich HM. PMID: 24975634; PMCID: PMC4167221.
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    134. Maternal smoking, xenobiotic metabolizing enzyme gene variants, and gastroschisis risk. Am J Med Genet A. 2014 Jun; 164A(6):1454-63. Jenkins MM, Reefhuis J, Gallagher ML, Mulle JG, Hoffmann TJ, Koontz DA, Sturchio C, Rasmussen SA, Witte JS, Richter P, Honein MA, National Birth Defects Prevention Study. PMID: 24668907; PMCID: PMC4382863.
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    135. Prediction of periodontal disease: modelling and validation in different general German populations. J Clin Periodontol. 2014 Mar; 41(3):224-31. Zhan Y, Holtfreter B, Meisel P, Hoffmann T, Micheelis W, Dietrich T, Kocher T. PMID: 24313816.
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    136. Functional characterization of SIM1-associated enhancers. Hum Mol Genet. 2014 Apr 01; 23(7):1700-8. Kim MJ, Oksenberg N, Hoffmann TJ, Vaisse C, Ahituv N. PMID: 24203700; PMCID: PMC3943516.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    137. B4-4: Genome-Wide Association Study of Macular Degeneration: Early Results from the Kaiser Permanente Research Program on Genes, Environment, and Health (RPGEH). Clinical Medicine & Research. 2013 Sep 1; 11(3):146-147. Jorgenson JE, Sciortino SS, Shen SL, Ranatunga RD, Hoffmann HT, Kvale KM, Banda BY, Kwok KP, Walter WL, Risch RN, Schaefer SC. .
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    138. PS3-15: Genome-Wide Association Study of Anxiety Disorders: Early Results from Kaiser Permanente’s Research Program on Genes, Environment, and Health (RPGEH). Clinical Medicine & Research. 2013 Sep 1; 11(3):149-149. Shen SL, Hoffmann HT, Kvale KM, Sakoda SL, Banda BY, Kwok KP, Risch RN, Jorgenson JE, Schaefer SC. .
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    139. African American race but not genome-wide ancestry is negatively associated with atrial fibrillation among postmenopausal women in the Women's Health Initiative. Am Heart J. 2013 Sep; 166(3):566-72. Perez MV, Hoffmann TJ, Tang H, Thornton T, Stefanick ML, Larson JC, Kooperberg C, Reiner AP, Caan B, Iribarren C, Risch N. PMID: 24016508.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    140. A genome-wide association study (GWAS) for bronchopulmonary dysplasia. Pediatrics. 2013 Aug; 132(2):290-7. Wang H, St Julien KR, Stevenson DK, Hoffmann TJ, Witte JS, Lazzeroni LC, Krasnow MA, Quaintance CC, Oehlert JW, Jelliffe-Pawlowski LL, Gould JB, Shaw GM, O'Brodovich HM. PMID: 23897914; PMCID: PMC3727675.
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    141. Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations. Am J Hum Genet. 2013 Jun 06; 92(6):904-16. Coram MA, Duan Q, Hoffmann TJ, Thornton T, Knowles JW, Johnson NA, Ochs-Balcom HM, Donlon TA, Martin LW, Eaton CB, Robinson JG, Risch NJ, Zhu X, Kooperberg C, Li Y, Reiner AP, Tang H. PMID: 23726366; PMCID: PMC3675231.
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    142. Adiponectin pathway polymorphisms and risk of breast cancer in African Americans and Hispanics in the Women's Health Initiative. Breast Cancer Res Treat. 2013 Jun; 139(2):461-8. Kaklamani VG, Hoffmann TJ, Thornton TA, Hayes G, Chlebowski R, Van Horn L, Mantzoros C. PMID: 23624817; PMCID: PMC3773607.
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    143. The impact of improved microarray coverage and larger sample sizes on future genome-wide association studies. Genet Epidemiol. 2013 May; 37(4):383-92. Lindquist KJ, Jorgenson E, Hoffmann TJ, Witte JS. PMID: 23529720; PMCID: PMC4291231.
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    144. Association of DXA-derived bone mineral density and fat mass with African ancestry. J Clin Endocrinol Metab. 2013 Apr; 98(4):E713-7. Ochs-Balcom HM, Preus L, Wactawski-Wende J, Nie J, Johnson NA, Zakharia F, Tang H, Carlson C, Carty C, Chen Z, Hoffman T, Hutter CM, Jackson RD, Kaplan RC, Li L, Liu S, Neuhouser ML, Peters U, Robbins J, Seldin MF, Thornton TA, Thompson CL, Kooperberg C, Sucheston LE. PMID: 23436924; PMCID: PMC3615193.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    145. Estimating kinship in admixed populations. Am J Hum Genet. 2012 Jul 13; 91(1):122-38. Thornton T, Tang H, Hoffmann TJ, Ochs-Balcom HM, Caan BJ, Risch N. PMID: 22748210; PMCID: PMC3397261.
      View in: PubMed   Mentions: 109     Fields:    Translation:Humans
    146. A genetic signature of spina bifida risk from pathway-informed comprehensive gene-variant analysis. PLoS One. 2011; 6(11):e28408. Marini NJ, Hoffmann TJ, Lammer EJ, Hardin J, Lazaruk K, Stein JB, Gilbert DA, Wright C, Lipzen A, Pennacchio LA, Carmichael SL, Witte JS, Shaw GM, Rine J. PMID: 22140583; PMCID: PMC3227667.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    147. Use of principal components to aggregate rare variants in case-control and family-based association studies in the presence of multiple covariates. BMC Proc. 2011 Nov 29; 5 Suppl 9:S29. Kazma R, Hoffmann TJ, Witte JS. PMID: 22373382; PMCID: PMC3287864.
      View in: PubMed   Mentions: 3  
    148. Design and coverage of high throughput genotyping arrays optimized for individuals of East Asian, African American, and Latino race/ethnicity using imputation and a novel hybrid SNP selection algorithm. Genomics. 2011 Dec; 98(6):422-30. Hoffmann TJ, Zhan Y, Kvale MN, Hesselson SE, Gollub J, Iribarren C, Lu Y, Mei G, Purdy MM, Quesenberry C, Rowell S, Shapero MH, Smethurst D, Somkin CP, Van den Eeden SK, Walter L, Webster T, Whitmer RA, Whitmer RA, Finn A, Schaefer C, Kwok PY, Risch N. PMID: 21903159; PMCID: PMC3502750.
      View in: PubMed   Mentions: 103     Fields:    Translation:Humans
    149. Next generation genome-wide association tool: design and coverage of a high-throughput European-optimized SNP array. Genomics. 2011 Aug; 98(2):79-89. Hoffmann TJ, Kvale MN, Hesselson SE, Zhan Y, Aquino C, Cao Y, Cawley S, Chung E, Connell S, Eshragh J, Ewing M, Gollub J, Henderson M, Hubbell E, Iribarren C, Kaufman J, Lao RZ, Lu Y, Ludwig D, Mathauda GK, McGuire W, Mei G, Miles S, Purdy MM, Quesenberry C, Ranatunga D, Rowell S, Sadler M, Shapero MH, Shen L, Shenoy TR, Smethurst D, Van den Eeden SK, Walter L, Wan E, Wearley R, Webster T, Wen CC, Weng L, Whitmer RA, Whitmer RA, Williams A, Wong SC, Zau C, Finn A, Schaefer C, Kwok PY, Risch N. PMID: 21565264; PMCID: PMC3146553.
      View in: PubMed   Mentions: 120     Fields:    Translation:Humans
    150. Parallel biocomputing. Source Code Biol Med. 2011 Mar 18; 6:4. Kompass KS, Hoffmann TJ, Witte JS. PMID: 21418580; PMCID: PMC3068083.
      View in: PubMed   Mentions:
    151. Combining disease models to test for gene-environment interaction in nuclear families. Biometrics. 2011 Dec; 67(4):1260-70. Hoffmann TJ, Vansteelandt S, Lange C, Silverman EK, DeMeo DL, Laird NM. PMID: 21401569; PMCID: PMC3120904.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    152. J Stat Softw. Parsing in command line arguments and parallel cluster/multicore batching in R with batch. 2011; 39. Hoffmann TJ.
    153. Passing in Command Line Arguments and Parallel Cluster/Multicore Batching in R with batch. J Stat Softw. 2011 Mar; 39. Hoffmann TJ. PMID: 25431538; PMCID: PMC4243301.
      View in: PubMed   Mentions: 1  
    154. Polygenic modeling of genome-wide association studies: an application to prostate and breast cancer. OMICS. 2011 Jun; 15(6):393-8. Witte JS, Hoffmann TJ. PMID: 21348634; PMCID: PMC3125548.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    155. Comprehensive approach to analyzing rare genetic variants. PLoS One. 2010 Nov 03; 5(11):e13584. Hoffmann TJ, Marini NJ, Witte JS. PMID: 21072163; PMCID: PMC2972202.
      View in: PubMed   Mentions: 90     Fields:    Translation:Humans
    156. Testing for non-random mating: evidence for ancestry-related assortative mating in the Framingham heart study. Genet Epidemiol. 2010 Nov; 34(7):674-9. Sebro R, Hoffman TJ, Lange C, Rogus JJ, Risch NJ. PMID: 20842694; PMCID: PMC3775670.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    157. Cluster analysis in severe emphysema subjects using phenotype and genotype data: an exploratory investigation. Respir Res. 2010 Mar 16; 11:30. Cho MH, Washko GR, Hoffmann TJ, Criner GJ, Hoffman EA, Martinez FJ, Laird N, Reilly JJ, Silverman EK. PMID: 20233420; PMCID: PMC2850331.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    158. Parsing the effects of individual SNPs in candidate genes with family data. Hum Hered. 2010; 69(2):91-103. Hoffmann TJ, Lange C, Vansteelandt S, Raby BA, DeMeo DL, Silverman EK, Weiss ST, Laird NM. PMID: 19996607; PMCID: PMC2956011.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    159. Gene-environment interaction tests for dichotomous traits in trios and sibships. Genet Epidemiol. 2009 Dec; 33(8):691-9. Hoffmann TJ, Lange C, Vansteelandt S, Laird NM. PMID: 19365860; PMCID: PMC3082448.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    160. More to learn about: periodontitis-related knowledge and its relationship with periodontal health behaviour. J Clin Periodontol. 2009 Sep; 36(9):756-64. Deinzer R, Micheelis W, Granrath N, Hoffmann T. PMID: 19659893.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansPHPublic Health
    161. fgui: A Method for Automatically Creating Graphical User Interfaces for Command-Line R Packages. J Stat Softw. 2009 Apr 01; 30(2). Hoffmann TJ, Laird NM. PMID: 21625291; PMCID: PMC3103229.
      View in: PubMed   Mentions: 5  
    162. P2BAT: a massive parallel implementation of PBAT for genome-wide association studies in R. Bioinformatics. 2006 Dec 15; 22(24):3103-5. Hoffmann T, Lange C. PMID: 17021156.
      View in: PubMed   Mentions: 10     Fields:    
    163. A randomized clinical trial comparing enamel matrix derivative and membrane treatment of buccal Class II furcation involvement in mandibular molars. Part I: Study design and results for primary outcomes. J Periodontol. 2004 Aug; 75(8):1150-60. Jepsen S, Heinz B, Jepsen K, Arjomand M, Hoffmann T, Richter S, Reich E, Sculean A, Gonzales JR, Bödeker RH, Meyle J. PMID: 15455745.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
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