Dr. Chung completed her MD (2001) at Johns Hopkins University where she was also an intern and resident (2001-04) in Internal Medicine. She was a Rheumatology Clinical Fellow at UCSF (2004-07), and joined the UCSF faculty in 2007. Dr. Chung completed a Master’s Degree in Advanced Studies in Clinical Research at UCSF (2008).
The central goal of Dr. Chung's research program is to discover genetic and epigenetic factors that influence autoimmune disease susceptibility and its manifestations, in order to identify biologic pathways involved in disease pathogenesis and potential targets for therapeutic intervention. Projects focused on systemic lupus erythematosus (SLE) have included genome-wide association studies, more focused investigations of the major histocompatilibity complex, and DNA methylation studies of specific disease manifestations. Her clinical interest is systemic vasculitis, and she directs the UCSF Vasculitis Clinic. Her research interests in vasculitis include genetic, epigenetic, and transcriptional studies of small vessel vasculitides. The UCSF Vasculitis Clinic is a member of the Vasculitis Clinical Research Consortium (VCRC), and the clinic participates in ongoing VCRC studies. Dr. Chung is also the chair of the American College of Rheumatology Vasculitis Guidelines development committee.
With the Immune Tolerance Network, Dr. Chung develops clinical trials that investigate novel approaches to induce immune tolerance in allergy and autoimmune diseases. These clinical trials utilize innovative therapeutic strategies to modulate the immune system, and have accompanying mechanistic studies to characterize the molecular, cellular, and serologic responses to therapy.