Christian Macdonald, PhD

Title(s)Postdoctoral Scholar, Bioengineering
SchoolSchool of Pharmacy
Address600 16th Street, #S476
San Francisco CA 94158
ORCID ORCID Icon0000-0002-0201-8832 Additional info
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Conserved regulatory motifs in the juxtamembrane domain and kinase N-lobe revealed through deep mutational scanning of the MET receptor tyrosine kinase domain. Elife. 2024 Sep 13; 12. Estevam GO, Linossi EM, Macdonald CB, Espinoza CA, Michaud JM, Coyote-Maestas W, Collisson EA, Jura N, Fraser JS. PMID: 39268701; PMCID: PMC11398868.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    2. Deep mutational scanning of EccD3 reveals the molecular basis of its essentiality in the mycobacterium ESX secretion system. bioRxiv. 2024 Aug 24. Trinidad DD, Macdonald CB, Rosenberg OS, Fraser JS, Coyote-Maestas W. PMID: 39229178; PMCID: PMC11370616.
      View in: PubMed   Mentions:
    3. Mapping kinase domain resistance mechanisms for the MET receptor tyrosine kinase via deep mutational scanning. bioRxiv. 2024 Jul 18. Estevam GO, Linossi EM, Rao J, Macdonald CB, Ravikumar A, Chrispens KM, Capra JA, Coyote-Maestas W, Pimentel H, Collisson EA, Jura N, Fraser JS. PMID: 39071407; PMCID: PMC11275805.
      View in: PubMed   Mentions:
    4. Conserved regulatory motifs in the juxtamembrane domain and kinase N-lobe revealed through deep mutational scanning of the MET receptor tyrosine kinase domain. bioRxiv. 2024 May 06. Estevam GO, Linossi EM, Macdonald CB, Espinoza CA, Michaud JM, Coyote-Maestas W, Collisson EA, Jura N, Fraser JS. PMID: 37577651; PMCID: PMC10418267.
      View in: PubMed   Mentions:
    5. The full spectrum of SLC22 OCT1 mutations illuminates the bridge between drug transporter biophysics and pharmacogenomics. Mol Cell. 2024 May 16; 84(10):1932-1947.e10. Yee SW, Macdonald CB, Mitrovic D, Zhou X, Koleske ML, Yang J, Buitrago Silva D, Rockefeller Grimes P, Trinidad DD, More SS, Kachuri L, Witte JS, Delemotte L, Giacomini KM, Coyote-Maestas W. PMID: 38703769; PMCID: PMC11382353.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    6. Molecular basis of proton-sensing by G protein-coupled receptors. bioRxiv. 2024 Apr 18. Howard MK, Hoppe N, Huang XP, Macdonald CB, Mehrota E, Grimes PR, Zahm A, Trinidad DD, English J, Coyote-Maestas W, Manglik A. PMID: 38659943; PMCID: PMC11042331.
      View in: PubMed   Mentions:
    7. DIMPLE: deep insertion, deletion, and missense mutation libraries for exploring protein variation in evolution, disease, and biology. Genome Biol. 2023 02 24; 24(1):36. Macdonald CB, Nedrud D, Grimes PR, Trinidad D, Fraser JS, Coyote-Maestas W. PMID: 36829241; PMCID: PMC9951526.
      View in: PubMed   Mentions: 17     Fields:    
    8. The structural basis of promiscuity in small multidrug resistance transporters. Nat Commun. 2020 11 27; 11(1):6064. Kermani AA, Macdonald CB, Burata OE, Ben Koff B, Koide A, Denbaum E, Koide S, Stockbridge RB. PMID: 33247110; PMCID: PMC7695847.
      View in: PubMed   Mentions: 21     Fields:    Translation:Cells
    9. Guanidinium export is the primal function of SMR family transporters. Proc Natl Acad Sci U S A. 2018 03 20; 115(12):3060-3065. Kermani AA, Macdonald CB, Gundepudi R, Stockbridge RB. PMID: 29507227; PMCID: PMC5866581.
      View in: PubMed   Mentions: 44     Fields:    Translation:Cells
    10. A topologically diverse family of fluoride channels. Curr Opin Struct Biol. 2017 08; 45:142-149. Macdonald CB, Stockbridge RB. PMID: 28514705; PMCID: PMC5612848.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    11. Antineoplastic agents. 599. Total synthesis of dolastatin 16. J Nat Prod. 2015 Mar 27; 78(3):476-85. Pettit GR, Smith TH, Arce PM, Flahive EJ, Anderson CR, Chapuis JC, Xu JP, Groy TL, Belcher PE, Macdonald CB. PMID: 25689568.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    12. Antineoplastic agents. 600. From the South Pacific Ocean to the silstatins. J Nat Prod. 2015 Mar 27; 78(3):510-23. Pettit GR, Arce PM, Chapuis JC, Macdonald CB. PMID: 25688575.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
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