Willow Coyote-Maestas, PhD, MS
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| Title(s) | Assistant Professor, Bioengineering |
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| School | School of Pharmacy |
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| Address | 1700 4th Street, #403E
San Francisco CA 94158
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| Pronouns | He/Him/His |
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ORCID
.gif) | 0000-0001-9614-5340  |
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| vCard | Download vCard |
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Biography
| The Evergreen State College, Olympia, WA | BS | 06/2014 | Chemistry |
| The Evergreen State College, Olympia, WA | BA | 06/2014 | Environmental Studies |
| University of Minnesota, Minneapolis, MN | MS | 11/2019 | Bioinformatics & Computational Biology |
| University of Minnesota, Twin Cities, Minneapolis, MN | PhD | 01/2021 | Biochemistry, Molecular Biology & Biophysics |
| National Science Foundation | 2013
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| 2014 | All Nations Louis Stokes Alliances for Minority Participation in STEM |
| National Science Foundation | 2017
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| 2018 | Graduate Research Fellowship |
| Howard Hughes Medical Institute | 2018
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| 2021 | Gilliam Fellow |
| University of Minnesota, Twin Cities | 2019 | | Ross A. Gortner Research Award |
| University of Minnesota, Twin Cities | 2020 | | Milne-Brandenbrug Research Award |
| Howard Hughes Medical Institute | 2021
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| 2027 | Hanna Gray Fellow |
| Quantitative Biology Institute | 2021
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| 2023 | Fellow |
| Chan Zuckerberg Biohub | 2023
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| 2028 | Investigator |
Overview
Bibliographic
Altmetrics Details
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media.
(Note that publications are often cited in additional ways that are not shown here.)
Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication.
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Mapping kinase domain resistance mechanisms for the MET receptor tyrosine kinase via deep mutational scanning. Elife. 2025 Feb 17; 13.
Estevam GO, Linossi E, Rao J, Macdonald CB, Ravikumar A, Chrispens KM, Capra JA, Coyote-Maestas W, Pimentel H, Collisson EA, Jura N, Fraser JS. PMID: 39960754; PMCID: PMC11832172.
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PubMed Mentions: Fields:
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Molecular basis of proton sensing by G protein-coupled receptors. Cell. 2025 Feb 06; 188(3):671-687.e20.
Howard MK, Hoppe N, Huang XP, Mitrovic D, Billesbølle CB, Macdonald CB, Mehrotra E, Rockefeller Grimes P, Trinidad DD, Delemotte L, English JG, Coyote-Maestas W, Manglik A. PMID: 39753132; PMCID: PMC11849372.
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PubMed Mentions:
2 Fields:
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Using multiplexed functional data to reduce variant classification inequities in underrepresented populations. Genome Med. 2024 Dec 03; 16(1):143.
Dawood M, Fayer S, Pendyala S, Post M, Kalra D, Patterson K, Venner E, Muffley LA, Fowler DM, Rubin AF, Posey JE, Plon SE, Lupski JR, Gibbs RA, Starita LM, Robles-Espinoza CD, Coyote-Maestas W, Gallego Romero I. PMID: 39627863; PMCID: PMC11616159.
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PubMed Mentions: Fields:
Translation:
Humans
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A Suite of Foundation Models Captures the Contextual Interplay Between Codons. bioRxiv. 2024 Oct 13.
Naghipourfar M, Chen S, Howard MK, Macdonald CB, Saberi A, Hagen T, Mofrad MRK, Coyote-Maestas W, Goodarzi H. PMID: 39416097; PMCID: PMC11482952.
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PubMed Mentions:
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Conserved regulatory motifs in the juxtamembrane domain and kinase N-lobe revealed through deep mutational scanning of the MET receptor tyrosine kinase domain. Elife. 2024 Sep 13; 12.
Estevam GO, Linossi EM, Macdonald CB, Espinoza CA, Michaud JM, Coyote-Maestas W, Collisson EA, Jura N, Fraser JS. PMID: 39268701; PMCID: PMC11398868.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Deep mutational scanning of EccD3 reveals the molecular basis of its essentiality in the mycobacterium ESX secretion system. bioRxiv. 2024 Aug 24.
Trinidad DD, Macdonald CB, Rosenberg OS, Fraser JS, Coyote-Maestas W. PMID: 39229178; PMCID: PMC11370616.
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PubMed Mentions:
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Rosace: a robust deep mutational scanning analysis framework employing position and mean-variance shrinkage. Genome Biol. 2024 05 24; 25(1):138.
Rao J, Xin R, Macdonald C, Howard MK, Estevam GO, Yee SW, Wang M, Fraser JS, Coyote-Maestas W, Pimentel H. PMID: 38789982; PMCID: PMC11127319.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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The full spectrum of SLC22 OCT1 mutations illuminates the bridge between drug transporter biophysics and pharmacogenomics. Mol Cell. 2024 May 16; 84(10):1932-1947.e10.
Yee SW, Macdonald CB, Mitrovic D, Zhou X, Koleske ML, Yang J, Buitrago Silva D, Rockefeller Grimes P, Trinidad DD, More SS, Kachuri L, Witte JS, Delemotte L, Giacomini KM, Coyote-Maestas W. PMID: 38703769; PMCID: PMC11382353.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Profiling the proximal proteome of the activated μ-opioid receptor. Nat Chem Biol. 2024 Sep; 20(9):1133-1143.
Polacco BJ, Lobingier BT, Blythe EE, Abreu N, Khare P, Howard MK, Gonzalez-Hernandez AJ, Xu J, Li Q, Novy B, Naing ZZC, Shoichet BK, Coyote-Maestas W, Levitz J, Krogan NJ, Von Zastrow M, Hüttenhain R. PMID: 38528119; PMCID: PMC11365811.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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DIMPLE: deep insertion, deletion, and missense mutation libraries for exploring protein variation in evolution, disease, and biology. Genome Biol. 2023 02 24; 24(1):36.
Macdonald CB, Nedrud D, Grimes PR, Trinidad D, Fraser JS, Coyote-Maestas W. PMID: 36829241; PMCID: PMC9951526.
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PubMed Mentions:
16 Fields:
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Determinants of trafficking, conduction, and disease within a K+ channel revealed through multiparametric deep mutational scanning. Elife. 2022 05 31; 11.
Coyote-Maestas W, Nedrud D, He Y, Schmidt D. PMID: 35639599; PMCID: PMC9273215.
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PubMed Mentions:
20 Fields:
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Probing ion channel functional architecture and domain recombination compatibility by massively parallel domain insertion profiling. Nat Commun. 2021 12 08; 12(1):7114.
Coyote-Maestas W, Nedrud D, Suma A, He Y, Matreyek KA, Fowler DM, Carnevale V, Myers CL, Schmidt D. PMID: 34880224; PMCID: PMC8654947.
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PubMed Mentions:
10 Fields:
Translation:
HumansCells
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ORACLE reveals a bright future to fight bacteria. Elife. 2021 04 15; 10.
Coyote-Maestas W, Fraser JS. PMID: 33856343; PMCID: PMC8049741.
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PubMed Mentions: Fields:
Translation:
HumansCells
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A large-scale survey of pairwise epistasis reveals a mechanism for evolutionary expansion and specialization of PDZ domains. Proteins. 2021 Feb 23.
Nedrud D, Coyote-Maestas W, Schmidt D. PMID: 33620761.
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PubMed Mentions:
7 Fields:
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Targeted insertional mutagenesis libraries for deep domain insertion profiling. Nucleic Acids Res. 2020 01 24; 48(2):e11.
Coyote-Maestas W, Nedrud D, Okorafor S, He Y, Schmidt D. PMID: 31745561; PMCID: PMC6954442.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Targeted insertional mutagenesis libraries for deep domain insertion profiling. Nucleic Acids Res. 2020 Jan 24; 48(2):1010.
Coyote-Maestas W, Nedrud D, Okorafor S, He Y, Schmidt D. PMID: 31799630; PMCID: PMC6954404.
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PubMed Mentions:
2 Fields:
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Domain insertion permissibility-guided engineering of allostery in ion channels. Nat Commun. 2019 01 17; 10(1):290.
Coyote-Maestas W, He Y, Myers CL, Schmidt D. PMID: 30655517; PMCID: PMC6336875.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Two distinct pools of B12 analogs reveal community interdependencies in the ocean. Proc Natl Acad Sci U S A. 2017 01 10; 114(2):364-369.
Heal KR, Qin W, Ribalet F, Bertagnolli AD, Coyote-Maestas W, Hmelo LR, Moffett JW, Devol AH, Armbrust EV, Stahl DA, Ingalls AE. PMID: 28028206; PMCID: PMC5240700.
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PubMed Mentions:
63 Fields:
Translation:
AnimalsCells
This graph shows the total number of publications by year. To see the data as text,
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| Year | Publications |
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| 2016 | 1 |
| 2019 | 1 |
| 2020 | 2 |
| 2021 | 3 |
| 2022 | 1 |
| 2023 | 1 |
| 2024 | 7 |
| 2025 | 2 |
This graph shows the number and percent of publications by field.
Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications.
Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written.
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This graph shows the number and percent of publications by field.
Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications.
Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written.
To see the data as text,
click here.
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