Natalia Jura, PhD

Title(s)Associate Professor, Cardiovascular Research Inst
SchoolSchool of Medicine
Address555 Mission Bay Blvd South
San Francisco CA 94158
Phone415-514-1133
ORCID ORCID Icon0000-0001-5129-641X Additional info
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    Collapse Research Activities and Funding
    Structural and Functional Studies of HER Receptors
    NIH R35GM139636Jan 1, 2021 - Nov 30, 2025
    Role: Principal Investigator
    Structural and functional investigation of the understudied HIPK1 kinase
    NIH R03TR003400Sep 1, 2020 - Aug 31, 2021
    Role: Principal Investigator
    The structural and functional basis of MET exon 14 activation and acquired drug resistance
    NIH R01CA230263Apr 1, 2019 - Mar 31, 2024
    Role: Principal Investigator
    FASEB SRC Protein Phosphorylation Networks in Health and Disease
    NIH R13CA232438Jul 6, 2018 - Jul 5, 2019
    Role: Principal Investigator
    Structural and Functional Studies of HER Receptor Tyrosine Kinases
    NIH R01GM109176Sep 1, 2014 - Aug 31, 2020
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Evolution of enhanced innate immune evasion by the SARS-CoV-2 B.1.1.7 UK variant. bioRxiv. 2021 Jun 07. Thorne LG, Bouhaddou M, Reuschl AK, Zuliani-Alvarez L, Polacco B, Pelin A, Batra J, Whelan MVX, Ummadi M, Rojc A, Turner J, Obernier K, Braberg H, Soucheray M, Richards A, Chen KH, Harjai B, Memon D, Hosmillo M, Hiatt J, Jahun A, Goodfellow IG, Fabius JM, Shokat K, Jura N, Verba K, Noursadeghi M, Beltrao P, Swaney DL, Garcia-Sastre A, Jolly C, Towers GJ, Krogan NJ. PMID: 34127972.
      View in: PubMed   Mentions:
    2. CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes. Res Sq. 2021 May 19. Verba K, Gupta M, Azumaya C, Moritz M, Pourmal S, Diallo A, Merz G, Jang G, Bouhaddou M, Fossati A, Brilot A, Diwanji D, Hernandez E, Herrera N, Kratochvil H, Lam V, Li F, Li Y, Nguyen H, Nowotny C, Owens T, Peters J, Rizo A, Schulze-Gahmen U, Smith A, Young I, Yu Z, Asarnow D, Billesbølle C, Campbell M, Chen J, Chen KH, Chio US, Dickinson M, Doan L, Jin M, Kim K, Li J, Li YL, Linossi E, Liu Y, Lo M, Lopez J, Lopez K, Mancino A, Iii FM, Paul M, Pawar K, Pelin A, Pospiech T, Puchades C, Remesh S, Safari M, Schaefer K, Sun M, Tabios M, Thwin A, Titus E, Trenker R, Tse E, Tsui TKM, Feng F, Zhang K, Zhang Y, Zhao J, Zhou F, Zhou Y, Zuliani-Alvarez L, Agard D, Cheng Y, Fraser J, Jura N, Kortemme T, Manglik A, Southworth D, Stroud R, Swaney D, Krogan N, Frost A, Rosenberg O. PMID: 34031651.
      View in: PubMed   Mentions:
    3. CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes. bioRxiv. 2021 May 11. Gupta M, Azumaya CM, Moritz M, Pourmal S, Diallo A, Merz GE, Jang G, Bouhaddou M, Fossati A, Brilot AF, Diwanji D, Hernandez E, Herrera N, Kratochvil HT, Lam VL, Li F, Li Y, Nguyen HC, Nowotny C, Owens TW, Peters JK, Rizo AN, Schulze-Gahmen U, Smith AM, Young ID, Yu Z, Asarnow D, Billesbølle C, Campbell MG, Chen J, Chen KH, Chio US, Dickinson MS, Doan L, Jin M, Kim K, Li J, Li YL, Linossi E, Liu Y, Lo M, Lopez J, Lopez KE, Mancino A, Moss FR, Paul MD, Pawar KI, Pelin A, Pospiech TH, Puchades C, Remesh SG, Safari M, Schaefer K, Sun M, Tabios MC, Thwin AC, Titus EW, Trenker R, Tse E, Tsui TKM, Wang F, Zhang K, Zhang Y, Zhao J, Zhou F, Zhou Y, Zuliani-Alvarez L, QCRG Structural Biology Consortium , Agard DA, Cheng Y, Fraser JS, Jura N, Kortemme T, Manglik A, Southworth DR, Stroud RM, Swaney DL, Krogan NJ, Frost A, Rosenberg OS, Verba KA. PMID: 34013269.
      View in: PubMed   Mentions:
    4. State of the structure address on MET receptor activation by HGF. Biochem Soc Trans. 2021 Apr 30; 49(2):645-661. Linossi EM, Estevam GO, Oshima M, Fraser JS, Collisson EA, Jura N. PMID: 33860789.
      View in: PubMed   Mentions:    Fields:    
    5. A survey of the kinome pharmacopeia reveals multiple scaffolds and targets for the development of novel anthelmintics. Sci Rep. 2021 Apr 28; 11(1):9161. Knox J, Joly N, Linossi EM, Carmona-Negrón JA, Jura N, Pintard L, Zuercher W, Roy PJ. PMID: 33911106.
      View in: PubMed   Mentions:    Fields:    
    6. Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking. Sci Adv. 2021 04; 7(16). Schuller M, Correy GJ, Gahbauer S, Fearon D, Wu T, Díaz RE, Young ID, Carvalho Martins L, Smith DH, Schulze-Gahmen U, Owens TW, Deshpande I, Merz GE, Thwin AC, Biel JT, Peters JK, Moritz M, Herrera N, Kratochvil HT, QCRG Structural Biology Consortium , Aimon A, Bennett JM, Brandao Neto J, Cohen AE, Dias A, Douangamath A, Dunnett L, Fedorov O, Ferla MP, Fuchs MR, Gorrie-Stone TJ, Holton JM, Johnson MG, Krojer T, Meigs G, Powell AJ, Rack JGM, Rangel VL, Russi S, Skyner RE, Smith CA, Soares AS, Wierman JL, Zhu K, O'Brien P, Jura N, Ashworth A, Irwin JJ, Thompson MC, Gestwicki JE, von Delft F, Shoichet BK, Fraser JS, Ahel I. PMID: 33853786.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    7. Human ACE2 receptor polymorphisms and altered susceptibility to SARS-CoV-2. Commun Biol. 2021 04 12; 4(1):475. Suryamohan K, Diwanji D, Stawiski EW, Gupta R, Miersch S, Liu J, Chen C, Jiang YP, Fellouse FA, Sathirapongsasuti JF, Albers PK, Deepak T, Saberianfar R, Ratan A, Washburn G, Mis M, Santhosh D, Somasekar S, Hiranjith GH, Vargas D, Mohan S, Phalke S, Kuriakose B, Antony A, Ustav M, Schuster SC, Sidhu S, Junutula JR, Jura N, Seshagiri S. PMID: 33846513.
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    8. Drugging the "Undruggable" MYCN Oncogenic Transcription Factor: Overcoming Previous Obstacles to Impact Childhood Cancers. Cancer Res. 2021 Apr 01; 81(7):1627-1632. Wolpaw AJ, Bayliss R, Büchel G, Dang CV, Eilers M, Gustafson WC, Hansen GH, Jura N, Knapp S, Lemmon MA, Levens D, Maris JM, Marmorstein R, Metallo SJ, Park JR, Penn LZ, Rape M, Roussel MF, Shokat KM, Tansey WP, Verba KA, Vos SM, Weiss WA, Wolf E, Mossé YP. PMID: 33509943.
      View in: PubMed   Mentions: 1     Fields:    
    9. Fragment Binding to the Nsp3 Macrodomain of SARS-CoV-2 Identified Through Crystallographic Screening and Computational Docking. bioRxiv. 2020 Nov 24. Schuller M, Correy GJ, Gahbauer S, Fearon D, Wu T, Díaz RE, Young ID, Martins LC, Smith DH, Schulze-Gahmen U, Owens TW, Deshpande I, Merz GE, Thwin AC, Biel JT, Peters JK, Moritz M, Herrera N, Kratochvil HT, QCRG Structural Biology Consortium , Aimon A, Bennett JM, Neto JB, Cohen AE, Dias A, Douangamath A, Dunnett L, Fedorov O, Ferla MP, Fuchs M, Gorrie-Stone TJ, Holton JM, Johnson MG, Krojer T, Meigs G, Powell AJ, Johannes Gregor Matthias Rack , Rangel VL, Russi S, Skyner RE, Smith CA, Soares AS, Wierman JL, Zhu K, Jura N, Ashworth A, Irwin J, Thompson MC, Gestwicki JE, von Delft F, Shoichet BK, Fraser JS, Ahel I. PMID: 33269349.
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    10. Expression and purification of active human kinases using Pichia pastoris as a general-purpose host. Protein Expr Purif. 2021 Mar; 179:105780. Abdel Aziz MH, Fan Y, Liu L, Moasser MM, Fu H, Jura N, Arkin MR. PMID: 33115654.
      View in: PubMed   Mentions:    Fields:    
    11. Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms. Science. 2020 12 04; 370(6521). Gordon DE, Hiatt J, Bouhaddou M, Rezelj VV, Ulferts S, Braberg H, Jureka AS, Obernier K, Guo JZ, Batra J, Kaake RM, Weckstein AR, Owens TW, Gupta M, Pourmal S, Titus EW, Cakir M, Soucheray M, McGregor M, Cakir Z, Jang G, O'Meara MJ, Tummino TA, Zhang Z, Foussard H, Rojc A, Zhou Y, Kuchenov D, Hüttenhain R, Xu J, Eckhardt M, Swaney DL, Fabius JM, Ummadi M, Tutuncuoglu B, Rathore U, Modak M, Haas P, Haas KM, Naing ZZC, Pulido EH, Shi Y, Barrio-Hernandez I, Memon D, Petsalaki E, Dunham A, Marrero MC, Burke D, Koh C, Vallet T, Silvas JA, Azumaya CM, Billesbølle C, Brilot AF, Campbell MG, Diallo A, Dickinson MS, Diwanji D, Herrera N, Hoppe N, Kratochvil HT, Liu Y, Merz GE, Moritz M, Nguyen HC, Nowotny C, Puchades C, Rizo AN, Schulze-Gahmen U, Smith AM, Sun M, Young ID, Zhao J, Asarnow D, Biel J, Bowen A, Braxton JR, Chen J, Chio CM, Chio US, Deshpande I, Doan L, Faust B, Flores S, Jin M, Kim K, Lam VL, Li F, Li J, Li YL, Li Y, Liu X, Lo M, Lopez KE, Melo AA, Moss FR, Nguyen P, Paulino J, Pawar KI, Peters JK, Pospiech TH, Safari M, Sangwan S, Schaefer K, Thomas PV, Thwin AC, Trenker R, Tse E, Tsui TKM, Wang F, Whitis N, Yu Z, Zhang K, Zhang Y, Zhou F, Saltzberg D, QCRG Structural Biology Consortium , Hodder AJ, Shun-Shion AS, Williams DM, White KM, Rosales R, Kehrer T, Miorin L, Moreno E, Patel AH, Rihn S, Khalid MM, Vallejo-Gracia A, Fozouni P, Simoneau CR, Roth TL, Wu D, Karim MA, Ghoussaini M, Dunham I, Berardi F, Weigang S, Chazal M, Park J, Logue J, McGrath M, Weston S, Haupt R, Hastie CJ, Elliott M, Brown F, Burness KA, Reid E, Dorward M, Johnson C, Wilkinson SG, Geyer A, Giesel DM, Baillie C, Raggett S, Leech H, Toth R, Goodman N, Keough KC, Lind AL, Zoonomia Consortium , Klesh RJ, Hemphill KR, Carlson-Stevermer J, Oki J, Holden K, Maures T, Pollard KS, Sali A, Agard DA, Cheng Y, Fraser JS, Frost A, Jura N, Kortemme T, Manglik A, Southworth DR, Stroud RM, Alessi DR, Davies P, Frieman MB, Ideker T, Abate C, Jouvenet N, Kochs G, Shoichet B, Ott M, Palmarini M, Shokat KM, García-Sastre A, Rassen JA, Grosse R, Rosenberg OS, Verba KA, Basler CF, Vignuzzi M, Peden AA, Beltrao P, Krogan NJ. PMID: 33060197.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansCells
    12. The structure of a calsequestrin filament reveals mechanisms of familial arrhythmia. Nat Struct Mol Biol. 2020 12; 27(12):1142-1151. Titus EW, Deiter FH, Shi C, Wojciak J, Scheinman M, Jura N, Deo RC. PMID: 33046906.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    13. An International Multicenter Evaluation of Inheritance Patterns, Arrhythmic Risks, and Underlying Mechanisms of CASQ2-Catecholaminergic Polymorphic Ventricular Tachycardia. Circulation. 2020 Sep 08; 142(10):932-947. Ng K, Titus EW, Lieve KV, Roston TM, Mazzanti A, Deiter FH, Denjoy I, Ingles J, Till J, Robyns T, Connors SP, Steinberg C, Abrams DJ, Pang B, Scheinman MM, Bos JM, Duffett SA, van der Werf C, Maltret A, Green MS, Rutberg J, Balaji S, Cadrin-Tourigny J, Orland KM, Knight LM, Brateng C, Wu J, Tang AS, Skanes AC, Manlucu J, Healey JS, January CT, Krahn AD, Collins KK, Maginot KR, Fischbach P, Etheridge SP, Eckhardt LL, Hamilton RM, Ackerman MJ, Noguer FRI, Semsarian C, Jura N, Leenhardt A, Gollob MH, Priori SG, Sanatani S, Wilde AAM, Deo RC, Roberts JD. PMID: 32693635.
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    14. A SARS-CoV-2 protein interaction map reveals targets for drug repurposing. Nature. 2020 07; 583(7816):459-468. Gordon DE, Jang GM, Bouhaddou M, Xu J, Obernier K, White KM, O'Meara MJ, Rezelj VV, Guo JZ, Swaney DL, Tummino TA, Hüttenhain R, Kaake RM, Richards AL, Tutuncuoglu B, Foussard H, Batra J, Haas K, Modak M, Kim M, Haas P, Polacco BJ, Braberg H, Fabius JM, Eckhardt M, Soucheray M, Bennett MJ, Cakir M, McGregor MJ, Li Q, Meyer B, Roesch F, Vallet T, Mac Kain A, Miorin L, Moreno E, Naing ZZC, Zhou Y, Peng S, Shi Y, Zhang Z, Shen W, Kirby IT, Melnyk JE, Chorba JS, Lou K, Dai SA, Barrio-Hernandez I, Memon D, Hernandez-Armenta C, Lyu J, Mathy CJP, Perica T, Pilla KB, Ganesan SJ, Saltzberg DJ, Rakesh R, Liu X, Rosenthal SB, Calviello L, Venkataramanan S, Liboy-Lugo J, Lin Y, Huang XP, Liu Y, Wankowicz SA, Bohn M, Safari M, Ugur FS, Koh C, Savar NS, Tran QD, Shengjuler D, Fletcher SJ, O'Neal MC, Cai Y, Chang JCJ, Broadhurst DJ, Klippsten S, Sharp PP, Wenzell NA, Kuzuoglu-Ozturk D, Wang HY, Trenker R, Young JM, Cavero DA, Hiatt J, Roth TL, Rathore U, Subramanian A, Noack J, Hubert M, Stroud RM, Frankel AD, Rosenberg OS, Verba KA, Agard DA, Ott M, Emerman M, Jura N, von Zastrow M, Verdin E, Ashworth A, Schwartz O, d'Enfert C, Mukherjee S, Jacobson M, Malik HS, Fujimori DG, Ideker T, Craik CS, Floor SN, Fraser JS, Gross JD, Sali A, Roth BL, Ruggero D, Taunton J, Kortemme T, Beltrao P, Vignuzzi M, García-Sastre A, Shokat KM, Shoichet BK, Krogan NJ. PMID: 32353859.
      View in: PubMed   Mentions: 859     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    15. A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing. bioRxiv. 2020 Mar 22. Gordon DE, Jang GM, Bouhaddou M, Xu J, Obernier K, O'Meara MJ, Guo JZ, Swaney DL, Tummino TA, Hüttenhain R, Kaake RM, Richards AL, Tutuncuoglu B, Foussard H, Batra J, Haas K, Modak M, Kim M, Haas P, Polacco BJ, Braberg H, Fabius JM, Eckhardt M, Soucheray M, Bennett MJ, Cakir M, McGregor MJ, Li Q, Naing ZZC, Zhou Y, Peng S, Kirby IT, Melnyk JE, Chorba JS, Lou K, Dai SA, Shen W, Shi Y, Zhang Z, Barrio-Hernandez I, Memon D, Hernandez-Armenta C, Mathy CJP, Perica T, Pilla KB, Ganesan SJ, Saltzberg DJ, Ramachandran R, Liu X, Rosenthal SB, Calviello L, Venkataramanan S, Lin Y, Wankowicz SA, Bohn M, Trenker R, Young JM, Cavero D, Hiatt J, Roth T, Rathore U, Subramanian A, Noack J, Hubert M, Roesch F, Vallet T, Meyer B, White KM, Miorin L, Agard D, Emerman M, Ruggero D, García-Sastre A, Jura N, von Zastrow M, Taunton J, Schwartz O, Vignuzzi M, d'Enfert C, Mukherjee S, Jacobson M, Malik HS, Fujimori DG, Ideker T, Craik CS, Floor S, Fraser JS, Gross J, Sali A, Kortemme T, Beltrao P, Shokat K, Shoichet BK, Krogan NJ. PMID: 32511329.
      View in: PubMed   Mentions:
    16. Receptor tyrosine kinase activation: From the ligand perspective. Curr Opin Cell Biol. 2020 04; 63:174-185. Trenker R, Jura N. PMID: 32114309.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    17. The crystal structure of the protein kinase HIPK2 reveals a unique architecture of its CMGC-insert region. J Biol Chem. 2019 09 13; 294(37):13545-13559. Agnew C, Liu L, Liu S, Xu W, You L, Yeung W, Kannan N, Jablons D, Jura N. PMID: 31341017.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    18. PEAK3/C19orf35 pseudokinase, a new NFK3 kinase family member, inhibits CrkII through dimerization. Proc Natl Acad Sci U S A. 2019 07 30; 116(31):15495-15504. Lopez ML, Lo M, Kung JE, Dudkiewicz M, Jang GM, Von Dollen J, Johnson JR, Krogan NJ, Pawlowski K, Jura N. PMID: 31311869.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    19. Prospects for pharmacological targeting of pseudokinases. Nat Rev Drug Discov. 2019 07; 18(7):501-526. Kung JE, Jura N. PMID: 30850748.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    20. The structure of a calsequestrin filament reveals mechanisms of familial arrhythmia. bioRxiv. 2019 Jun 15; 672303. Erron W. Titus, Frederick H. Deiter, Chenxu Shi, Julianne Wojciak, Melvin Scheinman, Natalia Jura, Rahul C. Deo. .
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    21. More than the sum of the parts: Toward full-length receptor tyrosine kinase structures. IUBMB Life. 2019 06; 71(6):706-720. Diwanji D, Thaker T, Jura N. PMID: 31046201.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    22. Functional role of PGAM5 multimeric assemblies and their polymerization into filaments. Nat Commun. 2019 01 31; 10(1):531. Ruiz K, Thaker TM, Agnew C, Miller-Vedam L, Trenker R, Herrera C, Ingaramo M, Toso D, Frost A, Jura N. PMID: 30705304.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    23. The pseudokinase TRIB1 toggles an intramolecular switch to regulate COP1 nuclear export. EMBO J. 2019 02 15; 38(4). Kung JE, Jura N. PMID: 30692133.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    24. Overexpression-mediated activation of MET in the Golgi promotes HER3/ERBB3 phosphorylation. Oncogene. 2019 03; 38(11):1936-1950. Frazier NM, Brand T, Gordan JD, Grandis J, Jura N. PMID: 30390071.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    25. Actionable Activating Oncogenic ERBB2/HER2 Transmembrane and Juxtamembrane Domain Mutations. Cancer Cell. 2018 11 12; 34(5):792-806.e5. Pahuja KB, Nguyen TT, Jaiswal BS, Prabhash K, Thaker TM, Senger K, Chaudhuri S, Kljavin NM, Antony A, Phalke S, Kumar P, Mravic M, Stawiski EW, Vargas D, Durinck S, Gupta R, Khanna-Gupta A, Trabucco SE, Sokol ES, Hartmaier RJ, Singh A, Chougule A, Trivedi V, Dutt A, Patil V, Joshi A, Noronha V, Ziai J, Banavali SD, Ramprasad V, DeGrado WF, Bueno R, Jura N, Seshagiri S. PMID: 30449325.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    26. Activating HER3 mutations in breast cancer. Oncotarget. 2018 Jun 12; 9(45):27773-27788. Mishra R, Alanazi S, Yuan L, Solomon T, Thaker TM, Jura N, Garrett JT. PMID: 29963236.
      View in: PubMed   Mentions: 6     Fields:    
    27. Phosphorylated EGFR Dimers Are Not Sufficient to Activate Ras. Cell Rep. 2018 03 06; 22(10):2593-2600. Liang SI, van Lengerich B, Eichel K, Cha M, Patterson DM, Yoon TY, von Zastrow M, Jura N, Gartner ZJ. PMID: 29514089.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    28. Regulation of Kinase Activity in the Caenorhabditis elegans EGF Receptor, LET-23. Structure. 2018 02 06; 26(2):270-281.e4. Liu L, Thaker TM, Freed DM, Frazier N, Malhotra K, Lemmon MA, Jura N. PMID: 29358026.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    29. Feedback regulation of RTK signaling in development. Dev Biol. 2019 03 01; 447(1):71-89. Neben CL, Lo M, Jura N, Klein OD. PMID: 29079424.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    30. Switching on BTK-One Domain at a Time. Structure. 2017 10 03; 25(10):1469-1470. Agnew C, Jura N. PMID: 28978404.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    31. EGF and NRG induce phosphorylation of HER3/ERBB3 by EGFR using distinct oligomeric mechanisms. Proc Natl Acad Sci U S A. 2017 04 04; 114(14):E2836-E2845. van Lengerich B, Agnew C, Puchner EM, Huang B, Jura N. PMID: 28320942.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    32. Structural Basis for the Non-catalytic Functions of Protein Kinases. Structure. 2016 Jan 05; 24(1):7-24. Kung JE, Jura N. PMID: 26745528.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    33. Src defines a new pool of EGFR substrates. Nat Struct Mol Biol. 2015 Dec; 22(12):945-7. Michael N, Jura N. PMID: 26643845.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    34. Analysis of the Role of the C-Terminal Tail in the Regulation of the Epidermal Growth Factor Receptor. Mol Cell Biol. 2015 Sep 01; 35(17):3083-102. Kovacs E, Das R, Wang Q, Collier TS, Cantor A, Huang Y, Wong K, Mirza A, Barros T, Grob P, Jura N, Bose R, Kuriyan J. PMID: 26124280.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    35. Structural Features of the Kinase Domain. Receptor Tyrosine Kinases: Structure, Functions and Role in Human Disease. 2015 Jan 1; 195-223. Dániel Süveges, Natalia Jura. .
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    36. Science Signaling Podcast: 2 December 2014. Science Signaling. 2014 Dec 2; 7(354):pc31-pc31. N. Jura, P. Littlefield, A. M. VanHook. .
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    37. Structural analysis of the EGFR/HER3 heterodimer reveals the molecular basis for activating HER3 mutations. Sci Signal. 2014 Dec 02; 7(354):ra114. Littlefield P, Liu L, Mysore V, Shan Y, Shaw DE, Jura N. PMID: 25468994.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    38. A robust methodology to subclassify pseudokinases based on their nucleotide-binding properties. Biochem J. 2014 Jan 15; 457(2):323-34. Murphy JM, Zhang Q, Young SN, Reese ML, Bailey FP, Eyers PA, Ungureanu D, Hammaren H, Silvennoinen O, Varghese LN, Chen K, Tripaydonis A, Jura N, Fukuda K, Qin J, Nimchuk Z, Mudgett MB, Elowe S, Gee CL, Liu L, Daly RJ, Manning G, Babon JJ, Lucet IS. PMID: 24107129.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansAnimalsCells
    39. Regulation of the HER3/ErbB3 Pseudokinase Domain by an ATP-Competitive Inhibitor. Biophysical Journal. 2014 Jan 1; 106(2):523a. Peter Littlefield, Mark M. Moasser, Natalia Jura. .
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    40. Single Molecule Imaging of Human Epidermal Growth Factor Receptors. Biophysical Journal. 2014 Jan 1; 106(2):239a. Bettina van Lengerich, Bo Huang, Natalia Jura. .
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    41. EGFR phosphorylates tumor-derived EGFRvIII driving STAT3/5 and progression in glioblastoma. Cancer Cell. 2013 Oct 14; 24(4):438-49. Fan QW, Cheng CK, Gustafson WC, Charron E, Zipper P, Wong RA, Chen J, Lau J, Knobbe-Thomsen C, Weller M, Jura N, Reifenberger G, Shokat KM, Weiss WA. PMID: 24135280.
      View in: PubMed   Mentions: 109     Fields:    Translation:HumansCells
    42. EGFR lung cancer mutants get specialized. Proc Natl Acad Sci U S A. 2013 Sep 17; 110(38):15169-70. Littlefield P, Jura N. PMID: 24023066.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    43. Catalytic control in the EGF receptor and its connection to general kinase regulatory mechanisms. Mol Cell. 2011 Apr 08; 42(1):9-22. Jura N, Zhang X, Endres NF, Seeliger MA, Schindler T, Kuriyan J. PMID: 21474065.
      View in: PubMed   Mentions: 137     Fields:    Translation:HumansCells
    44. Structural analysis of the catalytically inactive kinase domain of the human EGF receptor 3. Proc Natl Acad Sci U S A. 2009 Dec 22; 106(51):21608-13. Jura N, Shan Y, Cao X, Shaw DE, Kuriyan J. PMID: 20007378.
      View in: PubMed   Mentions: 140     Fields:    Translation:HumansCells
    45. Mechanism for Activation of the EGF Receptor Catalytic Domain by the Juxtamembrane Segment. Journal of End-to-End-testing. 2009 Aug 7; 138(3):604-604. Natalia Jura, Nicholas F. Endres, Kate Engel, Sebastian Deindl, Rahul Das, Meindert H. Lamers, David E. Wemmer, Xuewu Zhang, John Kuriyan. .
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    46. Mechanism for Activation of the EGF Receptor Catalytic Domain by the Juxtamembrane Segment. Journal of End-to-End-testing. 2009 Aug 7; 138(33):604-604. Natalia Jura, Nicholas F. Endres, Kate Engel, Sebastian Deindl, Rahul Das, Meindert H. Lamers, David E. Wemmer, Xuewu Zhang, John Kuriyan. .
      View in: Publisher Site   Mentions:
    47. Mechanism for Activation of the EGF Receptor Catalytic Domain by the Juxtamembrane Segment. Cell. 2009 Aug 1; 138(3):604. Natalia Jura, Nicholas F. Endres, Kate Engel, Sebastian Deindl, Rahul Das, Meindert H. Lamers, David E. Wemmer, Xuewu Zhang, John Kuriyan. .
      View in: Publisher Site   Mentions:
    48. Mechanism for activation of the EGF receptor catalytic domain by the juxtamembrane segment. Cell. 2009 Jun 26; 137(7):1293-307. Jura N, Endres NF, Engel K, Deindl S, Das R, Lamers MH, Wemmer DE, Zhang X, Kuriyan J. PMID: 19563760.
      View in: PubMed   Mentions: 239     Fields:    Translation:Cells
    49. Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface. Nature. 2007 Nov 29; 450(7170):741-4. Zhang X, Pickin KA, Bose R, Jura N, Cole PA, Kuriyan J. PMID: 18046415.
      View in: PubMed   Mentions: 147     Fields:    Translation:HumansAnimalsCells
    50. Mapping cellular routes of Ras: a ubiquitin trail. . 2006 Dec; 5(23):2744-7. Jura N, Bar-Sagi D. PMID: 17172849.
      View in: PubMed   Mentions:
    51. A mouse model of hereditary pancreatitis generated by transgenic expression of R122H trypsinogen. Gastroenterology. 2006 Dec; 131(6):1844-55. Archer H, Jura N, Keller J, Jacobson M, Bar-Sagi D. PMID: 17087933.
      View in: PubMed   Mentions: 35     Fields:    Translation:Animals
    52. Differential modification of Ras proteins by ubiquitination. Mol Cell. 2006 Mar 03; 21(5):679-87. Jura N, Scotto-Lavino E, Sobczyk A, Bar-Sagi D. PMID: 16507365.
      View in: PubMed   Mentions: 90     Fields:    Translation:AnimalsCells
    53. An ex vivo model for functional studies of myofibroblasts. Lab Invest. 2005 May; 85(5):643-54. Kilarski WW, Jura N, Gerwins P. PMID: 15723087.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    54. Inactivation of membrane tumor necrosis factor alpha by gingipains from Porphyromonas gingivalis. Infect Immun. 2005 Mar; 73(3):1506-14. Mezyk-Kopec R, Bzowska M, Potempa J, Bzowska M, Jura N, Sroka A, Black RA, Bereta J. PMID: 15731048.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    55. Chronic pancreatitis, pancreatic adenocarcinoma and the black box in-between. Cell Res. 2005 Jan; 15(1):72-7. Jura N, Archer H, Bar-Sagi D. PMID: 15686632.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimals
    56. Tumour necrosis factor-alpha stimulates expression of TNF-alpha converting enzyme in endothelial cells. Eur J Biochem. 2004 Jul; 271(13):2808-20. Bzowska M, Jura N, Lassak A, Black RA, Bereta J. PMID: 15206946.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    57. Inactivation of Src family kinases inhibits angiogenesis in vivo: implications for a mechanism involving organization of the actin cytoskeleton. Exp Cell Res. 2003 Nov 15; 291(1):70-82. Kilarski WW, Jura N, Gerwins P. PMID: 14597409.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    58. hSpry2 is targeted to the ubiquitin-dependent proteasome pathway by c-Cbl. Curr Biol. 2003 Feb 18; 13(4):308-14. Hall AB, Jura N, DaSilva J, Jang YJ, Gong D, Bar-Sagi D. PMID: 12593796.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansAnimalsCells
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