Jia Yang, PhD

Title(s)Assistant Researcher, Bioengineering
SchoolSchool of Pharmacy
ORCID ORCID Icon0000-0002-3992-4070 Additional info
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. The full spectrum of SLC22 OCT1 mutations illuminates the bridge between drug transporter biophysics and pharmacogenomics. Mol Cell. 2024 May 16; 84(10):1932-1947.e10. Yee SW, Macdonald CB, Mitrovic D, Zhou X, Koleske ML, Yang J, Buitrago Silva D, Rockefeller Grimes P, Trinidad DD, More SS, Kachuri L, Witte JS, Delemotte L, Giacomini KM, Coyote-Maestas W. PMID: 38703769.
      View in: PubMed   Mentions:
    2. Membrane transporters in drug development and as determinants of precision medicine. Nat Rev Drug Discov. 2024 Jan 24. Galetin A, Brouwer KLR, Tweedie D, Yoshida K, Sjöstedt N, Aleksunes L, Chu X, Evers R, Hafey MJ, Lai Y, Matsson P, Riselli A, Shen H, Sparreboom A, Varma MVS, Yang J, Yang X, Yee SW, Zamek-Gliszczynski MJ, Zhang L, Giacomini KM. PMID: 38267543.
      View in: PubMed   Mentions: 2     Fields:    
    3. Genetic Deletion of Thorase Causes Purkinje Cell Loss and Impaired Motor Coordination Behavior. Cells. 2023 08 10; 12(16). Li C, Zhang H, Tong K, Cai M, Gao F, Yang J, Xu Y, Wang H, Chen H, Hu Y, He W, Zhang J. PMID: 37626842; PMCID: PMC10453921.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    4. ATPase Thorase Deficiency Causes α-synucleinopathy and Parkinson’s Disease-Like Behavior by Impairing PINK1/Parkin-Mediated Mitophagy. Cells. 2022; 11(19):2990. Gao F, Zhang H, Yang J, Cai H, Yang Q, Wang H, Xu Y, Chen H, Hu Y, He W, and Zhang J.
    5. Early Differentiation of Irreversible Electroporation Ablation Regions With Radiomics Features of Conventional MRI. Acad Radiol. 2022 09; 29(9):1378-1386. Eresen A, Sun C, Zhou K, Shangguan J, Wang B, Pan L, Hu S, Ma Q, Yang J, Zhang Z, Yaghmai V. PMID: 34933803; PMCID: PMC10029937.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    6. Molecular Characterization of an Aquaporin-2 Mutation Causing Nephrogenic Diabetes Insipidus. Front Endocrinol (Lausanne). 2021; 12:665145. Li Q, Lu B, Yang J, Li C, Li Y, Chen H, Li N, Duan L, Gu F, Zhang J, Xia W. PMID: 34512542; PMCID: PMC8429928.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    7. TSPO deficiency accelerates amyloid pathology and neuroinflammation by impairing microglial phagocytosis. Neurobiol Aging. 2021 10; 106:292-303. Zhang H, Wang H, Gao F, Yang J, Xu Y, Fu Y, Cai M, Zhang X, Yang Q, Tong K, Hu Y, Chen H, Ma C, He W, Zhang J. PMID: 34340010.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    8. Combination of natural killer cell-based immunotherapy and irreversible electroporation for the treatment of hepatocellular carcinoma. Ann Transl Med. 2021 Jul; 9(13):1089. Eresen A, Yang J, Scotti A, Cai K, Yaghmai V, Zhang Z. PMID: 34423001; PMCID: PMC8339821.
      View in: PubMed   Mentions: 5  
    9. Irreversible electroporation ablation overcomes tumor-associated immunosuppression to improve the efficacy of DC vaccination in a mice model of pancreatic cancer. Oncoimmunology. 2021 02 02; 10(1):1875638. Yang J, Eresen A, Shangguan J, Ma Q, Yaghmai V, Zhang Z. PMID: 33643692; PMCID: PMC7872063.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCellsPHPublic Health
    10. Combination of NK-based immunotherapy and sorafenib against hepatocellular carcinoma. Am J Cancer Res. 2021; 11(2):337-349. Yang J, Eresen A, Scotti A, Cai K, Zhang Z. PMID: 33575075; PMCID: PMC7868752.
      View in: PubMed   Mentions: 5  
    11. Functional annotation of genetic associations by transcriptome-wide association analysis provides insights into neutrophil development regulation. Commun Biol. 2020 12 18; 3(1):790. Yao Y, Yang J, Qin Q, Tang C, Li Z, Chen L, Li K, Ren C, Chen L, Rao S. PMID: 33340029; PMCID: PMC7749173.
      View in: PubMed   Mentions: 2  Translation:HumansCells
    12. Intraprocedural Transcatheter Intraarterial Perfusion (TRIP)-MRI for Evaluation of Irreversible Electroporation Therapy Response in a Rabbit Liver Tumor Model. Clin Exp Gastroenterol. 2020; 13:543-553. Shangguan AJ, Zhou K, Yang J, Eresen A, Wang B, Sun C, Pan L, Hu S, Khan AT, Mouli SK, Yaghmai V, Zhang Z. PMID: 33192084; PMCID: PMC7654546.
      View in: PubMed   Mentions: 2  
    13. Effect of route of administration on the efficacy of dendritic cell vaccine in PDAC mice. Am J Cancer Res. 2020; 10(11):3911-3919. Yang J, Eresen A, Shangguan J, Ma Q, Zhang Z, Yaghmai V. PMID: 33294276; PMCID: PMC7716172.
      View in: PubMed   Mentions: 3  
    14. Preoperative prediction of perineural invasion and KRAS mutation in colon cancer using machine learning. J Cancer Res Clin Oncol. 2020 Dec; 146(12):3165-3174. Li Y, Eresen A, Shangguan J, Yang J, Benson AB, Yaghmai V, Zhang Z. PMID: 32779023.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    15. Detection of Immunotherapeutic Response in a Transgenic Mouse Model of Pancreatic Ductal Adenocarcinoma Using Multiparametric MRI Radiomics: A Preliminary Investigation. Acad Radiol. 2021 06; 28(6):e147-e154. Eresen A, Yang J, Shangguan J, Benson AB, Yaghmai V, Zhang Z. PMID: 32499156; PMCID: PMC7704817.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    16. Prediction of therapeutic outcome and survival in a transgenic mouse model of pancreatic ductal adenocarcinoma treated with dendritic cell vaccination or CDK inhibitor using MRI texture: a feasibility study. Am J Transl Res. 2020; 12(5):2201-2211. Eresen A, Yang J, Shangguan J, Li Y, Hu S, Sun C, Yaghmai V, Benson Iii AB, Zhang Z. PMID: 32509212; PMCID: PMC7270001.
      View in: PubMed   Mentions: 2  
    17. Preoperative assessment of lymph node metastasis in Colon Cancer patients using machine learning: a pilot study. Cancer Imaging. 2020 Apr 25; 20(1):30. Eresen A, Li Y, Yang J, Shangguan J, Velichko Y, Yaghmai V, Benson AB, Zhang Z. PMID: 32334635; PMCID: PMC7183701.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    18. No Evidence for Widespread Positive Selection Signatures in Common Risk Alleles Associated with Schizophrenia. Schizophr Bull. 2020 04 10; 46(3):603-611. Yao Y, Yang J, Xie Y, Liao H, Yang B, Xu Q, Rao S. PMID: 31150552; PMCID: PMC7147583.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    19. Dinaciclib prolongs survival in the LSL-KrasG12D/+ ; LSL-Trp53R172H/+ ; Pdx-1-Cre (KPC) transgenic murine models of pancreatic ductal adenocarcinoma. Am J Transl Res. 2020; 12(3):1031-1043. Yang J, Hu S, Shangguan J, Eresen A, Li Y, Ma Q, Yaghmai V, Benson Iii AB, Zhang Z. PMID: 32269732; PMCID: PMC7137051.
      View in: PubMed   Mentions: 2  
    20. MRI radiomics for early prediction of response to vaccine therapy in a transgenic mouse model of pancreatic ductal adenocarcinoma. J Transl Med. 2020 02 10; 18(1):61. Eresen A, Yang J, Shangguan J, Li Y, Hu S, Sun C, Velichko Y, Yaghmai V, Benson AB, Zhang Z. PMID: 32039734; PMCID: PMC7011246.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    21. Transcatheter Intraarterial Perfusion MRI Approaches to Differentiate Reversibly Electroporated Penumbra From Irreversibly Electroporated Zones in Rabbit Liver. Acad Radiol. 2020 12; 27(12):1727-1733. Pan L, Sun C, Zhou K, Figini M, Wang B, Shangguan J, Hu S, Yang J, Xing W, Wang J, Velichko Y, Yaghmai V, Zhang Z. PMID: 32033861; PMCID: PMC9945946.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    22. Contrast-enhanced CT radiomics for predicting lymph node metastasis in pancreatic ductal adenocarcinoma: a pilot study. Cancer Imaging. 2020 Jan 30; 20(1):12. Li K, Yao Q, Xiao J, Li M, Yang J, Hou W, Du M, Chen K, Qu Y, Li L, Li J, Wang X, Luo H, Yang J, Zhang Z, Chen W. PMID: 32000852; PMCID: PMC6993448.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    23. Prophylactic dendritic cell vaccination controls pancreatic cancer growth in a mouse model. Cytotherapy. 2020 01; 22(1):6-15. Shangguan A, Shang N, Figini M, Pan L, Yang J, Ma Q, Hu S, Eresen A, Sun C, Wang B, Velichko Y, Yaghmai V, Zhang Z. PMID: 32005355.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    24. Transcatheter intra-arterial perfusion (TRIP)-MRI biomarkers help detect immediate response to irreversible electroporation of rabbit VX2 liver tumor. Magn Reson Med. 2020 07; 84(1):365-374. Figini M, Zhou K, Pan L, Sun C, Wang B, Hu S, Yang J, Shangguan J, Eresen A, Velichko Y, Yaghmai V, Zhang Z. PMID: 31850550; PMCID: PMC7083687.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    25. Dendritic cell immunotherapy induces anti-tumor effect in a transgenic mouse model of pancreatic ductal adenocarcinoma. Am J Cancer Res. 2019; 9(11):2456-2468. Yang J, Hu S, Shangguan J, Eresen A, Li Y, Pan L, Ma Q, Velichko Y, Wang J, Hu C, Yaghmai V, Zhang Z. PMID: 31815046; PMCID: PMC6895456.
      View in: PubMed   Mentions: 5  
    26. Establishment of a new non-invasive imaging prediction model for liver metastasis in colon cancer. Am J Cancer Res. 2019; 9(11):2482-2492. Li Y, Eresen A, Shangguan J, Yang J, Lu Y, Chen D, Wang J, Velichko Y, Yaghmai V, Zhang Z. PMID: 31815048; PMCID: PMC6895455.
      View in: PubMed   Mentions: 15  
    27. Dendritic cells in pancreatic cancer immunotherapy: Vaccines and combination immunotherapies. Pathol Res Pract. 2019 Dec; 215(12):152691. Yang J, Shangguan J, Eresen A, Li Y, Wang J, Zhang Z. PMID: 31676092.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    28. Diffusion-Weighted MR Imaging to Evaluate Immediate Response to Irreversible Electroporation in a Rabbit VX2 Liver Tumor Model. J Vasc Interv Radiol. 2019 Nov; 30(11):1863-1869. Hu S, Sun C, Wang B, Zhou K, Pan L, Shangguan J, Yang J, Yaghmai V, Figini M, Zhang Z. PMID: 31542271.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    29. DWI and DCE-MRI approaches for differentiating reversibly electroporated penumbra from irreversibly electroporated ablation zones in a rabbit liver model. Am J Cancer Res. 2019; 9(9):1982-1994. Shangguan AJ, Sun C, Wang B, Pan L, Ma Q, Hu S, Yang J, Eresen A, Velichko Y, Yaghmai V, Zhang Z. PMID: 31598399; PMCID: PMC6780669.
      View in: PubMed   Mentions: 3  
    30. Natural killer cell-based adoptive transfer immunotherapy for pancreatic ductal adenocarcinoma in a KrasLSL-G12Dp53LSL-R172HPdx1-Cre mouse model. Am J Cancer Res. 2019; 9(8):1757-1765. Hu S, Yang J, Shangguan J, Eresen A, Li Y, Ma Q, Yaghmai V, Velichko Y, Hu C, Zhang Z. PMID: 31497356; PMCID: PMC6726992.
      View in: PubMed   Mentions: 8  
    31. Radiomics signature for the preoperative assessment of stage in advanced colon cancer. Am J Cancer Res. 2019; 9(7):1429-1438. Li Y, Eresen A, Lu Y, Yang J, Shangguan J, Velichko Y, Yaghmai V, Zhang Z. PMID: 31392079; PMCID: PMC6682712.
      View in: PubMed   Mentions: 18  
    32. Magnetic resonance imaging monitoring therapeutic response to dendritic cell vaccine in murine orthotopic pancreatic cancer models. Am J Cancer Res. 2019; 9(3):562-573. Pan L, Shang N, Shangguan J, Figini M, Xing W, Wang B, Sun C, Yang J, Zhang Y, Hu S, Ma Q, Wang J, Velichko Y, Yaghmai V, Benson AB, Zhang Z. PMID: 30949410; PMCID: PMC6448058.
      View in: PubMed   Mentions: 8  
    33. MRI Assessment of Associations between Brown Adipose Tissue and Cachexia in Murine Pancreatic Ductal Adenocarcinoma. Intern Med Open Access. 2019; 9(1). Zhang Y, Hu S, Shangguan J, Pan L, Zhou X, Yaghmai V, Velichko Y, Hu C, Yang J, Zhang Z. PMID: 31073508; PMCID: PMC6502254.
      View in: PubMed   Mentions: 6  
    34. Non-invasive Imaging Methods for Brown Adipose Tissue Detection and Function Evaluation. Intern Med Open Access. 2018; 8(6). Zhang Y, Hu X, Hu S, Scotti A, Cai K, Wang J, Zhou X, Yang D, Figini M, Pan L, Shangguan J, Yang J, Zhang Z. PMID: 31080698; PMCID: PMC6508884.
      View in: PubMed   Mentions: 4  
    35. Non-invasive dynamic monitoring initiation and growth of pancreatic tumor in the LSL-KrasG12D/+;LSL-Trp53R172H/+;Pdx-1-Cre (KPC) transgenic mouse model. J Immunol Methods. 2019 02; 465:1-6. Hu S, Pan L, Shangguan J, Figini M, Eresen A, Sun C, Wang B, Ma Q, Hu C, Yaghmai V, Velichko Y, Yang J, Zhang Z. PMID: 30468734.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    36. The AAA + ATPase Thorase is neuroprotective against ischemic injury. J Cereb Blood Flow Metab. 2019 09; 39(9):1836-1848. Zhang J, Yang J, Wang H, Sherbini O, Keuss MJ, Umanah GK, Pai EL, Chi Z, Paldanius KM, He W, Wang H, Andrabi SA, Dawson TM, Dawson VL. PMID: 29658368; PMCID: PMC6727130.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    37. Mitophagy in Parkinson's Disease: Pathogenic and Therapeutic Implications. Front Neurol. 2017; 8:527. Gao F, Yang J, Wang D, Li C, Fu Y, Wang H, He W, Zhang J. PMID: 29046661; PMCID: PMC5632845.
      View in: PubMed   Mentions: 41  
    38. Global Deletion of TSPO Does Not Affect the Viability and Gene Expression Profile. PLoS One. 2016; 11(12):e0167307. Wang H, Zhai K, Xue Y, Yang J, Yang Q, Fu Y, Hu Y, Liu F, Wang W, Cui L, Chen H, Zhang J, He W. PMID: 27907096; PMCID: PMC5131929.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    39. High-Content Genome-Wide RNAi Screen Reveals CCR3 as a Key Mediator of Neuronal Cell Death. eNeuro. 2016 Sep-Oct; 3(5). Zhang J, Wang H, Sherbini O, Ling-Lin Pai E, Kang SU, Kwon JS, Yang J, He W, Wang H, Eacker SM, Chi Z, Mao X, Xu J, Jiang H, Andrabi SA, Dawson TM, Dawson VL. PMID: 27822494; PMCID: PMC5075945.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
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