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George Carlson, PhD

Address675 Nelson Rising Lane
San Francisco CA 94158
Phone406-454-6001
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    Collapse Research 
    Collapse Research Activities and Funding
    CNS Stem Cells for neurodegenerative disease research
    NIH/NIA R21AG044720Aug 15, 2014 - May 31, 2016
    Role: Principal Investigator
    CNS Stem Cells for Alzheimer's Disease Therapy
    NIH/NIA R41AG022736Sep 30, 2004 - Mar 31, 2006
    Role: Principal Investigator
    24-Capillary Reveal Mutation Discovery System
    NIH/NCRR S10RR017764May 1, 2003 - Apr 30, 2004
    Role: Principal Investigator
    Genetics of Prion Susceptibility in vitro
    NIH/NINDS P01NS041997Sep 30, 2001 - Jun 30, 2013
    Role: Principal Investigator
    ANIMAL FACILITY IMPROVEMENT
    NIH/NCRR G20RR007976Sep 30, 1992 - Sep 29, 1993
    Role: Principal Investigator
    SMALL INSTRUMENTATION GRANT
    NIH/NIA S15AG011109Sep 1, 1992 - Aug 31, 1993
    Role: Principal Investigator
    TRANSGENIC MODELS FOR ALZHEIMERS DISEASE
    NIH/NIA R01AG010681Sep 29, 1991 - Jun 30, 1998
    Role: Principal Investigator
    SMALL INSTRUMENTATION GRANT
    NIH/NCI S15CA056002Sep 1, 1991 - Aug 31, 1992
    Role: Principal Investigator
    SMALL INSTRUMENTATION GRANT
    NIH/NIGMS S15GM045468Jun 1, 1990 - May 31, 1991
    Role: Principal Investigator
    MINORITY HIGH SCHOOL STUDENT RESEARCH APPRENTICE PROGRAM
    NIH/NCRR S03RR003526Mar 1, 1990 - Aug 31, 1994
    Role: Principal Investigator
    BIOMEDICAL RESEARCH SUPPORT GRANT
    NIH/NCRR S07RR006017Apr 1, 1989 - Sep 29, 1992
    Role: Principal Investigator
    MITOTIC RECOMBINATION IN MAMMALIAN CELLS
    NIH/NIGMS R01GM037821Jul 1, 1987 - Jun 30, 1991
    Role: Principal Investigator
    TRANSMISSIBLE AND GENETIC NEURODENGENERATIVE DISEASES
    NIH/NINDS P01NS022786Sep 1, 1985 - Jun 30, 2000
    Role: Co-Principal Investigator
    H-2 ASSOCIATED NATURAL RESISTANCE
    NIH/NCI R01CA028231Jul 1, 1980 - Dec 31, 1991
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Young ZT, Rauch JN, Assimon VA, Jinwal UK, Ahn M, Li X, Dunyak BM, Ahmad A, Carlson G, Srinivasan SR, Zuiderweg ER, Dickey CA, Gestwicki JE. Stabilizing the Hsp70-Tau Complex Promotes Turnover in Models of Tauopathy. Cell Chem Biol. 2016 Aug 18; 23(8):992-1001. PMID: 27499529.
      View in: PubMed
    2. Ahn M, Kalume F, Pitstick R, Oehler A, Carlson G, DeArmond SJ. Brain Aggregates: An Effective In Vitro Cell Culture System Modeling Neurodegenerative Diseases. J Neuropathol Exp Neurol. 2016 Mar; 75(3):256-62. PMID: 26851378.
      View in: PubMed
    3. Silvius D, Pitstick R, Ahn M, Meishery D, Oehler A, Barsh GS, DeArmond SJ, Carlson G, Gunn TM. Levels of the Mahogunin Ring Finger 1 E3 ubiquitin ligase do not influence prion disease. PLoS One. 2013; 8(1):e55575. PMID: 23383230; PMCID: PMC3559536.
    4. Bajsarowicz K, Ahn M, Ackerman L, Dearmond BN, Carlson G, DeArmond SJ. A brain aggregate model gives new insights into the pathobiology and treatment of prion diseases. J Neuropathol Exp Neurol. 2012 May; 71(5):449-66. PMID: 22507918.
      View in: PubMed
    5. Hnasko R, Serban AV, Carlson G, Prusiner SB, Stanker LH. Generation of antisera to purified prions in lipid rafts. Prion. 2010 Apr-Jun; 4(2):94-104. PMID: 20647769; PMCID: PMC2933057.
    6. Watts JC, Huo H, Bai Y, Ehsani S, Jeon AH, Won AH, Shi T, Daude N, Lau A, Young R, Xu L, Carlson G, Williams D, Westaway D, Schmitt-Ulms G. Interactome analyses identify ties of PrP and its mammalian paralogs to oligomannosidic N-glycans and endoplasmic reticulum-derived chaperones. PLoS Pathog. 2009 Oct; 5(10):e1000608. PMID: 19798432; PMCID: PMC2749441.
    7. Tamgüney G, Giles K, Glidden DV, Lessard P, Wille H, Tremblay P, Groth DF, Yehiely F, Korth C, Moore RC, Tatzelt J, Rubinstein E, Boucheix C, Yang X, Stanley P, Lisanti MP, Dwek RA, Rudd PM, Moskovitz J, Epstein CJ, Cruz TD, Kuziel WA, Maeda N, Sap J, Ashe KH, Carlson G, Tesseur I, Wyss-Coray T, Mucke L, Weisgraber KH, Mahley RW, Cohen FE, Prusiner SB. Genes contributing to prion pathogenesis. J Gen Virol. 2008 Jul; 89(Pt 7):1777-88. PMID: 18559949; PMCID: PMC2828448.
    8. Park L, Zhou P, Pitstick R, Capone C, Anrather J, Norris EH, Younkin L, Younkin S, Carlson G, McEwen BS, Iadecola C. Nox2-derived radicals contribute to neurovascular and behavioral dysfunction in mice overexpressing the amyloid precursor protein. Proc Natl Acad Sci U S A. 2008 Jan 29; 105(4):1347-52. PMID: 18202172; PMCID: PMC2234141.
    9. Watts JC, Drisaldi B, Ng V, Yang J, Strome B, Horne P, Sy MS, Yoong L, Young R, Mastrangelo P, Bergeron C, Fraser PE, Carlson G, Mount HT, Schmitt-Ulms G, Westaway D. The CNS glycoprotein Shadoo has PrP(C)-like protective properties and displays reduced levels in prion infections. EMBO J. 2007 Sep 5; 26(17):4038-50. PMID: 17703189; PMCID: PMC1950727.
    10. Giri RK, Young R, Pitstick R, DeArmond SJ, Prusiner SB, Carlson G. Prion infection of mouse neurospheres. Proc Natl Acad Sci U S A. 2006 Mar 7; 103(10):3875-80. PMID: 16495413; PMCID: PMC1533787.
    11. Yehiely F, Bamborough P, Da Costa M, Perry BJ, Thinakaran G, Cohen FE, Carlson G, Prusiner SB. Identification of candidate proteins binding to prion protein. Neurobiol Dis. 1997; 3(4):339-55. PMID: 9173930.
      View in: PubMed
    12. Westaway D, Carlson G, Prusiner SB. On safari with PrP: prion diseases of animals. Trends Microbiol. 1995 Apr; 3(4):141-7. PMID: 7613755.
      View in: PubMed
    13. Westaway D, Cooper C, Turner S, Da Costa M, Carlson G, Prusiner SB. Structure and polymorphism of the mouse prion protein gene. Proc Natl Acad Sci U S A. 1994 Jul 5; 91(14):6418-22. PMID: 7912827; PMCID: PMC44213.
    14. Westaway D, DeArmond SJ, Cayetano-Canlas J, Groth D, Foster D, Yang SL, Torchia M, Carlson G, Prusiner SB. Degeneration of skeletal muscle, peripheral nerves, and the central nervous system in transgenic mice overexpressing wild-type prion proteins. Cell. 1994 Jan 14; 76(1):117-29. PMID: 8287472.
      View in: PubMed
    15. Prusiner SB, Scott M, Foster D, Pan KM, Groth D, Mirenda C, Torchia M, Yang SL, Serban D, Carlson G. Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication. Cell. 1990 Nov 16; 63(4):673-86. PMID: 1977523.
      View in: PubMed
    16. Scott M, Foster D, Mirenda C, Serban D, Coufal F, Wälchli M, Torchia M, Groth D, Carlson G, DeArmond SJ, Westaway D, Prusiner SB. Transgenic mice expressing hamster prion protein produce species-specific scrapie infectivity and amyloid plaques. Cell. 1989 Dec 1; 59(5):847-57. PMID: 2574076.
      View in: PubMed
    17. Gabizon R, McKinley MP, Groth D, Westaway D, DeArmond SJ, Carlson G, Prusiner SB. Immunoaffinity purification and neutralization of scrapie prions. Prog Clin Biol Res. 1989; 317:583-600. PMID: 2574871.
      View in: PubMed
    18. Westaway D, Goodman PA, Mirenda CA, McKinley MP, Carlson G, Prusiner SB. Distinct prion proteins in short and long scrapie incubation period mice. Cell. 1987 Nov 20; 51(4):651-62. PMID: 2890436.
      View in: PubMed
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